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Disease on EC 3.4.21.B42 - hippostasin

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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Adenocarcinoma
KLK11 mRNA expression predicts poor disease-free and overall survival in colorectal adenocarcinoma patients.
Adenoma
Human kallikrein gene 11 (KLK11) mRNA overexpression is associated with poor prognosis in patients with epithelial ovarian cancer.
beta-Thalassemia
Demonstration of kallikrein-like protease activity in nonactivated plasma of patients with Cooley's anemia.
Brain Neoplasms
Immunoreactivity, ultrastructural localization, and transcript expression of prostate-specific antigen in human neuroblastoma cell lines.
Breast Neoplasms
Bioregulation of kallikrein-related peptidases 6, 10 and 11 by the kinin B? receptor in breast cancer cells.
Intracellular signaling pathways regulate hormone-dependent kallikrein gene expression.
Kallikrein 11 expressed in human breast cancer cells releases insulin-like growth factor through degradation of IGFBP-3.
Novel Biomarkers Aim at Detecting Metastatic Sentinel Lymph Nodes in Breast Cancer
Carcinogenesis
KLK11 suppresses cellular proliferation via inhibition of Wnt/?-catenin signaling pathway in esophageal squamous cell carcinoma.
Carcinoma
Diagnostic and prognostic biomarker potential of kallikrein family genes in different cancer types.
Favorable prognostic value of tissue human kallikrein 11 (hK11) in patients with ovarian carcinoma.
Human kallikrein 11: a new biomarker of prostate and ovarian carcinoma.
Human kallikrein gene 11 (KLK11) mRNA overexpression is associated with poor prognosis in patients with epithelial ovarian cancer.
KLK11 acts as a tumor-inhibitor in laryngeal squamous cell carcinoma through the inactivation of Akt/Wnt/?-catenin signaling.
KLK11 suppresses cellular proliferation via inhibition of Wnt/?-catenin signaling pathway in esophageal squamous cell carcinoma.
Over-expression of human kallikrein 11 is associated with poor prognosis in patients with low rectal carcinoma.
Pentraxin-3 is a Novel Biomarker of Lung Carcinoma.
Prognostic significance of human tissue kallikrein-related peptidases 11 and 15 in gastric cancer.
Validation and characterization of human kallikrein 11 as a serum marker for diagnosis of ovarian carcinoma.
Carcinoma, Hepatocellular
Diagnostic and prognostic biomarker potential of kallikrein family genes in different cancer types.
Carcinoma, Non-Small-Cell Lung
Is Human Kallikrein 11 in Non-small Cell Lung Cancer Treated Chemoradiotherapy Associated with Survival?
Carcinoma, Renal Cell
Diagnostic and prognostic biomarker potential of kallikrein family genes in different cancer types.
Cardiomegaly
KLK11 promotes the activation of mTOR and protein synthesis to facilitate cardiac hypertrophy.
Colonic Neoplasms
The use of kallikrein-related peptidases as adjuvant prognostic markers in colorectal cancer.
Colorectal Neoplasms
KLK11 mRNA expression predicts poor disease-free and overall survival in colorectal adenocarcinoma patients.
Knockdown of KLK11 inhibits cell proliferation and increases oxaliplatin sensitivity in human colorectal cancer.
Knockdown of KLK11 reverses oxaliplatin resistance by inhibiting proliferation and activating apoptosis via suppressing the PI3K/AKT signal pathway in colorectal cancer cell.
Dermatitis, Atopic
Human tissue kallikrein expression in the stratum corneum and serum of atopic dermatitis patients.
Dry Eye Syndromes
Elevated Immunoglobulin to Tissue KLK11 in Patients With Sjögren Syndrome.
Esophageal Squamous Cell Carcinoma
KLK11 suppresses cellular proliferation via inhibition of Wnt/?-catenin signaling pathway in esophageal squamous cell carcinoma.
hippostasin deficiency
KLK11 suppresses cellular proliferation via inhibition of Wnt/?-catenin signaling pathway in esophageal squamous cell carcinoma.
Laryngeal Neoplasms
Diagnostic and prognostic significance of human kallikrein 11 (KLK11) mRNA expression levels in patients with laryngeal cancer.
Lung Neoplasms
Decreased kallikrein 11 messenger RNA expression in lung cancer.
Expression of the human kallikrein genes 10 (KLK10) and 11 (KLK11) in cancerous and non-cancerous lung tissues.
Is Human Kallikrein 11 in Non-small Cell Lung Cancer Treated Chemoradiotherapy Associated with Survival?
Pentraxin-3 is a Novel Biomarker of Lung Carcinoma.
Lymphatic Metastasis
Kallikrein-11, in Association with Coiled-Coil Domain Containing 25, as a Potential Prognostic Marker for Cholangiocarcinoma with Lymph Node Metastasis.
Prognostic significance of human tissue kallikrein-related peptidases 11 and 15 in gastric cancer.
Mesothelioma
Global Gene Expression Profiling of Pleural Mesotheliomas: Overexpression of Aurora Kinases and P16/CDKN2A Deletion as Prognostic Factors and Critical Evaluation of Microarray-Based Prognostic Prediction.
Nasopharyngeal Carcinoma
Diagnostic and prognostic values of KLK11 in nasopharyngeal carcinoma.
Neoplasm Metastasis
Development of a survival prediction model for gastric cancer using serine proteases and their inhibitors.
Identification and validation of Kallikrein-ralated peptidase 11 as a novel prognostic marker of gastric cancer based on immunohistochemistry.
Kallikrein-11, in Association with Coiled-Coil Domain Containing 25, as a Potential Prognostic Marker for Cholangiocarcinoma with Lymph Node Metastasis.
Prognostic significance of human tissue kallikrein-related peptidases 11 and 15 in gastric cancer.
The diagnostic and prognostic value of serum human kallikrein-related peptidases 11 in non-small cell lung cancer.
Neoplasm, Residual
Clinical relevance of kallikrein-related peptidase 9, 10, 11, and 15 mRNA expression in advanced high-grade serous ovarian cancer.
Neoplasms
Association of TMPRSS2 and KLK11 gene expression levels with clinical progression of human prostate cancer.
Cancer-associated fibroblast stimulates cancer cell invasion in an interleukin-1 receptor (IL-1R)-dependent manner.
Development of a survival prediction model for gastric cancer using serine proteases and their inhibitors.
Diagnostic and prognostic significance of human kallikrein 11 (KLK11) mRNA expression levels in patients with laryngeal cancer.
Elevated tumor tissue protein expression levels of kallikrein-related peptidases KLK10 and KLK11 are associated with a better prognosis in advanced high-grade serous ovarian cancer patients.
Expression analysis and prognostic significance of human kallikrein 11 in prostate cancer.
Human kallikrein gene 11 (KLK11) mRNA overexpression is associated with poor prognosis in patients with epithelial ovarian cancer.
Identification and validation of Kallikrein-ralated peptidase 11 as a novel prognostic marker of gastric cancer based on immunohistochemistry.
Immunohistochemical localization and analysis of kallikrein-related peptidase 7 and 11 expression in paired cancer and benign foci in prostate cancer patients.
Kallikrein 11 expressed in human breast cancer cells releases insulin-like growth factor through degradation of IGFBP-3.
Kallikrein-11, in Association with Coiled-Coil Domain Containing 25, as a Potential Prognostic Marker for Cholangiocarcinoma with Lymph Node Metastasis.
KLK11 acts as a tumor-inhibitor in laryngeal squamous cell carcinoma through the inactivation of Akt/Wnt/?-catenin signaling.
KLK11 mRNA expression predicts poor disease-free and overall survival in colorectal adenocarcinoma patients.
Knockdown of KLK11 inhibits cell proliferation and increases oxaliplatin sensitivity in human colorectal cancer.
Normal prostate-derived stromal cells stimulate prostate cancer development.
Novel Biomarkers Aim at Detecting Metastatic Sentinel Lymph Nodes in Breast Cancer
Novel splice variants of the human kallikrein-related peptidases 11 (KLK11) and 12 (KLK12), unraveled by next-generation sequencing technology.
Pentraxin-3 is a Novel Biomarker of Lung Carcinoma.
Prognostic significance of human tissue kallikrein-related peptidases 11 and 15 in gastric cancer.
Quantitative analysis of hippostasin/KLK11 gene expression in cancerous and noncancerous prostatic tissues.
Neuroblastoma
Immunoreactivity, ultrastructural localization, and transcript expression of prostate-specific antigen in human neuroblastoma cell lines.
Ovarian Neoplasms
Clinical relevance of kallikrein-related peptidase 9, 10, 11, and 15 mRNA expression in advanced high-grade serous ovarian cancer.
Elevated tumor tissue protein expression levels of kallikrein-related peptidases KLK10 and KLK11 are associated with a better prognosis in advanced high-grade serous ovarian cancer patients.
Human kallikrein 11: an indicator of favorable prognosis in ovarian cancer patients.
Human kallikrein gene 11 (KLK11) mRNA overexpression is associated with poor prognosis in patients with epithelial ovarian cancer.
Parallel overexpression of seven kallikrein genes in ovarian cancer.
Purification and characterization of human kallikrein 11, a candidate prostate and ovarian cancer biomarker, from seminal plasma.
Validation and characterization of human kallikrein 11 as a serum marker for diagnosis of ovarian carcinoma.
Pancreatic Neoplasms
Kallikrein-Related Peptidase 6 Is Associated with the Tumour Microenvironment of Pancreatic Ductal Adenocarcinoma.
Prostatic Hyperplasia
mRNA expression analysis of human kallikrein 11 (KLK11) may be useful in the discrimination of benign prostatic hyperplasia from prostate cancer after needle prostate biopsy.
The usefulness of serum human kallikrein 11 for discriminating between prostate cancer and benign prostatic hyperplasia.
Prostatic Neoplasms
Alternative splicing isoforms of hippostasin (PRSS20/KLK11) in prostate cancer cell lines.
Association of TMPRSS2 and KLK11 gene expression levels with clinical progression of human prostate cancer.
Expression analysis and prognostic significance of human kallikrein 11 in prostate cancer.
Immunohistochemical localization and analysis of kallikrein-related peptidase 7 and 11 expression in paired cancer and benign foci in prostate cancer patients.
Improved prostate cancer detection with a human kallikrein 11 and percentage free PSA-based artificial neural network.
Is there a role for serum human tissue kallikrein in detection of prostate cancer?
Molecular cloning and expression of a variant form of hippostasin/KLK11 in prostate.
mRNA expression analysis of human kallikrein 11 (KLK11) may be useful in the discrimination of benign prostatic hyperplasia from prostate cancer after needle prostate biopsy.
Quantitative analysis of hippostasin/KLK11 gene expression in cancerous and noncancerous prostatic tissues.
The usefulness of serum human kallikrein 11 for discriminating between prostate cancer and benign prostatic hyperplasia.
Treatment of PC3 prostate cancer cells with mitoxantrone, etoposide, doxorubicin and carboplatin induces distinct alterations in the expression of kallikreins 5 and 11.
Psoriasis
Aberrant human tissue kallikrein levels in the stratum corneum and serum of patients with psoriasis: dependence on phenotype, severity and therapy.
Seizures
Nerve agent poisoning in primates: antilethal, anti-epileptic and neuroprotective effects of GK-11.
Squamous Cell Carcinoma of Head and Neck
KLK11 acts as a tumor-inhibitor in laryngeal squamous cell carcinoma through the inactivation of Akt/Wnt/?-catenin signaling.
Stomach Neoplasms
Identification and validation of Kallikrein-ralated peptidase 11 as a novel prognostic marker of gastric cancer based on immunohistochemistry.