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Information on EC 3.4.21.B26 - proprotein convertase 5

for references in articles please use BRENDA:EC3.4.21.B26
preliminary BRENDA-supplied EC number
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EC Tree
     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.21 Serine endopeptidases
                3.4.21.B26 proprotein convertase 5
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Word Map
The enzyme appears in viruses and cellular organisms
Reaction Schemes
cleavage at the RX(K/R)R consensus motif. Release of mature proteins from their proproteins by cleavage of Arg-Xaa-Yaa-Arg-/-Zaa bonds, where Xaa can be any amino acid and Yaa is Arg or Lys.
Synonyms
pc5/6, pcsk5, pc5/6a, pc5-a, proprotein convertase 5/6, prohormone convertase 5, pc5-b, proprotein convertase subtilisin/kexin type 5, proprotein convertase pc5/6, subtilisin/kexin type 5, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
cleavage at the RX(K/R)R consensus motif. Release of mature proteins from their proproteins by cleavage of Arg-Xaa-Yaa-Arg-/-Zaa bonds, where Xaa can be any amino acid and Yaa is Arg or Lys.
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