Disease on EC 3.4.21.53 - Endopeptidase La
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Abdominal Abscess
Crystal structure of hemoglobin protease, a heme binding autotransporter protein from pathogenic Escherichia coli.
Aberrant Crypt Foci
LonP1 Differently Modulates Mitochondrial Function and Bioenergetics of Primary Versus Metastatic Colon Cancer Cells.
Abnormalities, Multiple
Metabolic Abnormalities Associated with the Use of Protease Inhibitors and Non-nucleoside Reverse Transcriptase Inhibitors.
Abortion, Habitual
Association of the R67X and W303X non-sense polymorphisms in the protein Z-dependent protease inhibitor gene with idiopathic recurrent miscarriage.
Abortion, Habitual
Increase in the plasma levels of protein Z-dependent protease inhibitor in normal pregnancies but not in non-pregnant patients with unexplained recurrent miscarriage.
Abortion, Spontaneous
Miscarriage among women in the United States Women's Interagency HIV Study, 1994-2017.
Abortion, Spontaneous
Role of cathepsin E in decidual macrophage of patients with recurrent miscarriage.
Abortion, Spontaneous
The expression of cathepsin D, oestrogen receptor and progestogen receptor in hydatidiform mole--an immunohistochemical study.
Abscess
Alteration of proteins reacting with antibody to toxic shock syndrome toxin 1 by endogenous proteases of Staphylococcus aureus.
Abscess
Characterization of volatile sulphur production by pathogenic and non-pathogenic strains of oral Bacteroides.
Abscess
Diagnosis of Corynebacterium pyogenes infection in pigs by immunodiffusion test with protease antigen.
Abscess
Escherichia coli hemoglobin protease autotransporter contributes to synergistic abscess formation and heme-dependent growth of Bacteroides fragilis.
Abscess
Profiling of Candida albicans Gene Expression During Intra-abdominal Candidiasis Identifies Biologic Processes Involved in Pathogenesis.
Abscess
The role of Pseudomonas aeruginosa elastase in corneal ring abscess formation in pseudomonal keratitis.
Acanthamoeba Keratitis
Characterization of a plasminogen activator produced by Acanthamoeba castellanii.
Acanthamoeba Keratitis
Protease-activated receptor 2 (PAR2) is upregulated by Acanthamoeba plasminogen activator (aPA) and induces proinflammatory cytokine in human corneal epithelial cells.
Acanthamoeba Keratitis
Role of contact lens wear, bacterial flora, and mannose-induced pathogenic protease in the pathogenesis of amoebic keratitis.
Acantholysis
Cantharide acantholysis: endogenous protease activation leading to desmosomal plaque dissolution.
Acantholysis
Cantharidin-induced acantholysis: adhesion molecules, proteases, and related proteins.
Acantholysis
Effects of steroid, retinoid, and protease inhibitors on the formation of acantholysis induced in organ culture of skins from patients with benign familial chronic pemphigus.
Acantholysis
Pemphigus can be induced by topical phenol as well as by foods and drugs that contain phenols or thiols.
Acantholysis
Protease inhibitors prevent plasminogen-mediated, but not pemphigus vulgaris-induced, acantholysis in human epidermis.
Acantholysis
Urokinase plasminogen activator mRNA is induced by IL-1alpha and TNF-alpha in in vitro acantholysis.
Acanthosis Nigricans
Acanthosis nigricans: a new manifestation of insulin resistance in patients receiving treatment with protease inhibitors.
Achlorhydria
Protease inhibitors in patients with HIV disease. Clinically important pharmacokinetic considerations.
Acidosis
A review of nanoparticle drug delivery systems responsive to endogenous breast cancer microenvironment.
Acidosis
Lung Protection Strategies during Cardiopulmonary Bypass Affect the Composition of Bronchoalveolar Fluid and Lung Tissue in Cardiac Surgery Patients.
Acidosis
[Role of hemosorption in the therapy of infectious toxic shock and the multiple-organ failure syndrome in a fulminating form of meningococcemia]
Acidosis, Lactic
Defective mitochondrial protease LonP1 can cause classical mitochondrial disease.
Acidosis, Lactic
Highly active antiretroviral therapy (HAART)-associated lactic acidosis: in vitro effects of combination of nucleoside analogues and protease inhibitors on mitochondrial function and lactic acid production.
Acidosis, Lactic
Identification of proteasome gene regulation in a rat model for HIV protease inhibitor-induced hyperlipidemia.
Acne Vulgaris
Anti Propionibacterium acnes activity of rhodomyrtone, an effective compound from Rhodomyrtus tomentosa (Aiton) Hassk. leaves.
Acne Vulgaris
Bioengineering a humanized acne microenvironment model: proteomics analysis of host responses to Propionibacterium acnes infection in vivo.
Acne Vulgaris
Developing an in vitro artificial sebum model to study Propionibacterium acnes biofilms.
Acne Vulgaris
Enzyme production of propionibacteria from patients with acne vulgaris and healthy persons.
Acne Vulgaris
Lipase, protease, and biofilm as the major virulence factors in staphylococci isolated from acne lesions.
Acne Vulgaris
Protease-activated receptor-2 mediates the expression of inflammatory cytokines, antimicrobial peptides, and matrix metalloproteinases in keratinocytes in response to Propionibacterium acnes.
Acquired Immunodeficiency Syndrome
A 'second life' agenda. Psychiatric research issues raised by protease inhibitor treatments for people with the human immunodeficiency virus or the acquired immunodeficiency syndrome.
Acquired Immunodeficiency Syndrome
A case-control study of HIV-associated pancreatic abnormalities during HAART era. Focus on emerging risk factors and specific management.
Acquired Immunodeficiency Syndrome
A conserved hydrogen-bonding network of P2 bis-tetrahydrofuran-containing HIV-1 protease inhibitors (PIs) with a protease active-site amino acid backbone aids in their activity against PI-resistant HIV.
Acquired Immunodeficiency Syndrome
A mimic of HIV-1 nucleocapsid protein impairs reverse transcription and displays antiviral activity.
Acquired Immunodeficiency Syndrome
A multistep approach to structure-based drug design: studying ligand binding at the human neutrophil elastase.
Acquired Immunodeficiency Syndrome
A new serine-protease fold revealed by the crystal structure of human cytomegalovirus protease.
Acquired Immunodeficiency Syndrome
A New, Rapid and Simple RP-HPLC Method for Stability Quantification of a Protease Inhibitor in Tablets.
Acquired Immunodeficiency Syndrome
Aboriginal status is a prognostic factor for mortality among antiretroviral naïve HIV-positive individuals first initiating HAART.
Acquired Immunodeficiency Syndrome
ABT-538 is a potent inhibitor of human immunodeficiency virus protease and has high oral bioavailability in humans.
Acquired Immunodeficiency Syndrome
Active site mutagenesis of the AIDS virus protease and its alleviation by trans complementation.
Acquired Immunodeficiency Syndrome
Acute cytomegalovirus infection in AIDS patients with CD4 counts above 100 x 10(6) cells/l following combination antiretroviral therapy including protease inhibitors.
Acquired Immunodeficiency Syndrome
AIDS and cancer in the era of highly active antiretroviral therapy (HAART).
Acquired Immunodeficiency Syndrome
AIDS task force grapples with faster access to protease drugs.
Acquired Immunodeficiency Syndrome
Amino acid substitutions in Gag protein at non-cleavage sites are indispensable for the development of a high multitude of HIV-1 resistance against protease inhibitors.
Acquired Immunodeficiency Syndrome
An Increased Risk of Osteoporosis during Acquired Immunodeficiency Syndrome.
Acquired Immunodeficiency Syndrome
An inhibitor of HIV-1 protease modulates proteasome activity, antigen presentation, and T cell responses.
Acquired Immunodeficiency Syndrome
Anti-HIV effect of iron chelators: different mechanisms involved.
Acquired Immunodeficiency Syndrome
Antibody response to human immunodeficiency virus type 1 protease according to risk group and disease stage.
Acquired Immunodeficiency Syndrome
Antiretroviral medication adherence and class- specific resistance in a large prospective clinical trial.
Acquired Immunodeficiency Syndrome
Are there gender differences in starting protease inhibitors, HAART, and disease progression despite equal access to care?
Acquired Immunodeficiency Syndrome
Atherosclerosis and central adiposity in a pediatric patient with AIDS treated with HAART: autopsy findings.
Acquired Immunodeficiency Syndrome
Back to a Future: One Man's AIDS Tale Shows How Quickly Epidemic Has Turned.
Acquired Immunodeficiency Syndrome
Beneficial effects of protease inhibitors on body composition and energy expenditure: a comparison between HIV-infected and AIDS patients.
Acquired Immunodeficiency Syndrome
Biochemical and genetic definition of the cellular protease required for HIV-1 gp160 processing.
Acquired Immunodeficiency Syndrome
Biochemical Manifestation of HIV Lipodystrophy Syndrome.
Acquired Immunodeficiency Syndrome
Biological and biochemical inhibitors of the NF-kappa B/Rel proteins and cytokine synthesis.
Acquired Immunodeficiency Syndrome
Bioprospecting endophytic fungi from Fusarium genus as sources of bioactive metabolites.
Acquired Immunodeficiency Syndrome
Carrier rate of zidovudine-resistant HIV-1: the impact of failing therapy on transmission of resistant strains.
Acquired Immunodeficiency Syndrome
Case report of long-term survival in a patient with acquired immunodeficiency syndrome and cryptococcal meningitis.
Acquired Immunodeficiency Syndrome
CC3-02: Risk Factors for Short-term Virologic Outcomes Among HIV-infected Patients Undergoing Regimen Switch of Combination Antiretroviral Therapy.
Acquired Immunodeficiency Syndrome
Cell-based fluorescence assay for human immunodeficiency virus type 1 protease activity.
Acquired Immunodeficiency Syndrome
Cellular entry of HIV: Evaluation of therapeutic targets.
Acquired Immunodeficiency Syndrome
Changes in CD4+ cell count and the risk of opportunistic infection or death after highly active antiretroviral treatment. Groupe d'Epidémiologie Clinique du SIDA en Aquitaine.
Acquired Immunodeficiency Syndrome
Changes in Insulin Resistance After Initiation of Raltegravir or Protease Inhibitors With Tenofovir-Emtricitabine: AIDS Clinical Trials Group A5260s.
Acquired Immunodeficiency Syndrome
Characterization of specificity of subtilisin Carlsberg towards peptide T by high-performance liquid chromatography and electrospray mass spectrometry.
Acquired Immunodeficiency Syndrome
Chemotherapeutic agents for human immunodeficiency virus infection: mechanism of action, pharmacokinetics, metabolism, and adverse reactions.
Acquired Immunodeficiency Syndrome
Clinical validation and applicability of different tipranavir/ritonavir genotypic scores in HIV-1 protease inhibitor-experienced patients.
Acquired Immunodeficiency Syndrome
Coevolution and subsite decomposition for the design of resistance-evading HIV-1 protease inhibitors.
Acquired Immunodeficiency Syndrome
Combination antiretroviral therapy improves psychomotor speed performance in HIV-seropositive homosexual men. Multicenter AIDS Cohort Study (MACS).
Acquired Immunodeficiency Syndrome
Combination therapy of resistant warts in a patient with AIDS.
Acquired Immunodeficiency Syndrome
Comparative studies on retroviral proteases: substrate specificity.
Acquired Immunodeficiency Syndrome
Comparison of algorithms that interpret genotypic HIV-1 drug resistance to determine the prevalence of transmitted drug resistance.
Acquired Immunodeficiency Syndrome
Comparison of antiretroviral drug resistance among treatment-naive and treated HIV-infected individuals in Shiraz, Iran.
Acquired Immunodeficiency Syndrome
Comparison of prognostic importance of latest CD4+ cell count and HIV RNA levels in patients with advanced HIV infection on highly active antiretroviral therapy.
Acquired Immunodeficiency Syndrome
Comprehensive bioinformatic analysis of the specificity of human immunodeficiency virus type 1 protease.
Acquired Immunodeficiency Syndrome
Computational studies on HIV-1 protease inhibitors: influence of calculated inhibitor-enzyme binding affinities on the statistical quality of 3D-QSAR CoMFA models.
Acquired Immunodeficiency Syndrome
Computational studies reveal Fluorine based quinolines to be potent inhibitors for proteins involved in SARS-CoV-2 assembly.
Acquired Immunodeficiency Syndrome
Computer simulations of slow progression of human immunodeficiency virus infection and relapse during anti-HIV treatment with reverse transcriptase inhibitors and protease inhibitors.
Acquired Immunodeficiency Syndrome
Conformational flexibility of the catalytic Asp dyad in HIV-1 protease: An ab initio study on the free enzyme.
Acquired Immunodeficiency Syndrome
Contribution of antibody response to recombinant HIV-1 gene-encoded products nef, rev, tat, and protease in predicting development of AIDS in HIV-1-infected individuals.
Acquired Immunodeficiency Syndrome
Cord blood lipids in infants born to HIV-1-infected women treated with combination antiretroviral therapy.
Acquired Immunodeficiency Syndrome
Curling of flap tips in HIV-1 protease as a mechanism for substrate entry and tolerance of drug resistance.
Acquired Immunodeficiency Syndrome
Current and future antiretroviral treatment options in paediatric HIV infection.
Acquired Immunodeficiency Syndrome
Cystoid macular edema in a patient with acquired immunodeficiency syndrome and past ocular history of cytomegalovirus retinitis after initiation of protease inhibitors.
Acquired Immunodeficiency Syndrome
Declining incidence of AIDS and increasing prevalence of AIDS presenters among AIDS patients in Italy.
Acquired Immunodeficiency Syndrome
Design, synthesis and biological evaluation of heteroaryl diketohexenoic and diketobutanoic acids as HIV-1 integrase inhibitors endowed with antiretroviral activity.
Acquired Immunodeficiency Syndrome
Designed multiple ligands: an emerging anti-HIV drug discovery paradigm.
Acquired Immunodeficiency Syndrome
Designing HIV integrase inhibitors--shooting the last arrow.
Acquired Immunodeficiency Syndrome
Dietary fat alters HIV protease inhibitor-induced metabolic changes in mice.
Acquired Immunodeficiency Syndrome
Differential adherence to combination antiretroviral therapy is associated with virological failure with resistance.
Acquired Immunodeficiency Syndrome
Differential impact of combination antiretroviral therapy in preventing Kaposi's sarcoma with and without visceral involvement.
Acquired Immunodeficiency Syndrome
Discordant Associations Between SLCO1B1 521T?C and Plasma Levels of Ritonavir-boosted Protease Inhibitors in AIDS Clinical Trials Group Study A5146.
Acquired Immunodeficiency Syndrome
Discovery and Development of anti-HIV Therapeutic Agents: Progress Towards Improved HIV Medication.
Acquired Immunodeficiency Syndrome
Discovery of a small molecule Tat-trans-activation-responsive RNA antagonist that potently inhibits human immunodeficiency virus-1 replication.
Acquired Immunodeficiency Syndrome
Disposition of indinavir, a potent HIV-1 protease inhibitor, after an oral dose in humans.
Acquired Immunodeficiency Syndrome
Economic impact of delaying or preventing AIDS in persons with HIV.
Acquired Immunodeficiency Syndrome
Effect of antiretroviral protease inhibitors alone, and in combination with paromomycin, on the excystation, invasion and in vitro development of Cryptosporidium parvum.
Acquired Immunodeficiency Syndrome
Effect of highly active antiretroviral therapy on survival in patients with AIDS-associated pulmonary Kaposi's sarcoma treated with chemotherapy.
Acquired Immunodeficiency Syndrome
Effect of HIV aspartyl protease inhibitors on experimental infection with a cystogenic Me49 strain of Toxoplasma gondii.
Acquired Immunodeficiency Syndrome
Effectiveness of potent antiretroviral therapy on time to AIDS and death in men with known HIV infection duration. Multicenter AIDS Cohort Study Investigators.
Acquired Immunodeficiency Syndrome
Effects of HIV protease, nucleoside/non-nucleoside reverse transcriptase inhibitors on Bax, Bcl-2 and apoptosis in two cervical cell lines.
Acquired Immunodeficiency Syndrome
Effects of protease inhibitors on the course of CMV retinitis in relation to CD4+ lymphocyte responses in HIV+ patients.
Acquired Immunodeficiency Syndrome
Efficacy of once-daily darunavir/ritonavir 800/100 mg in HIV-infected, treatment-experienced patients with no baseline resistance-associated mutations to darunavir.
Acquired Immunodeficiency Syndrome
Electronic transduction of HIV-1 drug resistance in AIDS patients.
Acquired Immunodeficiency Syndrome
Emergence of uncommon HIV-1 non-B subtypes and circulating recombinant forms and trends in transmission of antiretroviral drug resistance in patients with primary infection during the 2013-2015 period in Marseille, Southeastern France.
Acquired Immunodeficiency Syndrome
Endoplasmic reticulum stress links dyslipidemia to inhibition of proteasome activity and glucose transport by HIV protease inhibitors.
Acquired Immunodeficiency Syndrome
Estimating the population impact in Australia of improved antiretroviral treatment for HIV infection.
Acquired Immunodeficiency Syndrome
Evaluation of HIV protease and nucleoside reverse transcriptase inhibitors on proliferation, necrosis, apoptosis in intestinal epithelial cells and electrolyte and water transport and epithelial barrier function in mice.
Acquired Immunodeficiency Syndrome
Exercise-induced pulmonary hypertension in HIV patients: Association with poor clinical and immunological status.
Acquired Immunodeficiency Syndrome
Expression of secretory leukocyte proteinase inhibitor in the submandibular glands of AIDS patients.
Acquired Immunodeficiency Syndrome
Extracellular enzymatic activity and serotype of Cryptococcus neoformans strains isolated from AIDS patients in Brazil.
Acquired Immunodeficiency Syndrome
Extracorporeal whole body hyperthermia treatments for HIV infection and AIDS.
Acquired Immunodeficiency Syndrome
FDA approvals include two new AIDS drugs, pediatric labeling for two protease inhibitors.
Acquired Immunodeficiency Syndrome
Finding the structural requirements of diverse HIV-1 protease inhibitors using multiple QSAR modelling for lead identification.
Acquired Immunodeficiency Syndrome
Finding, Conducting, and Nurturing Science: A Virologist's Memoir.
Acquired Immunodeficiency Syndrome
Four-limb acute ischemia induced by ergotamine in an AIDS patient treated with protease inhibitors.
Acquired Immunodeficiency Syndrome
Fragment-Based QSAR and Structural Analysis of a Series of Hydroxyethylamine Derivatives as HIV-1 Protease Inhibitors.
Acquired Immunodeficiency Syndrome
Gender differences in health-related quality of life in patients with HIV/AIDS.
Acquired Immunodeficiency Syndrome
Genotypic resistance profile and clinical progression of treatment-experienced HIV type 1-infected patients with virological failure.
Acquired Immunodeficiency Syndrome
Hepatotoxicity associated with antiretroviral therapy containing HIV-1 protease inhibitors.
Acquired Immunodeficiency Syndrome
Herpes zoster as an immune restoration disease in AIDS patients during therapy including protease inhibitors.
Acquired Immunodeficiency Syndrome
High incidence of herpes zoster in patients with AIDS soon after therapy with protease inhibitors.
Acquired Immunodeficiency Syndrome
High prevalence of genotypic and phenotypic HIV-1 drug-resistant strains among patients receiving antiretroviral therapy in Abidjan, Côte d'Ivoire.
Acquired Immunodeficiency Syndrome
High throughput screening and characterization of HIV-1 entry inhibitors targeting gp41: theories and techniques.
Acquired Immunodeficiency Syndrome
Highly resistant HIV-1 proteases and strategies for their inhibition.
Acquired Immunodeficiency Syndrome
HIV infection and the pancreas: risk factors and potential management guidelines.
Acquired Immunodeficiency Syndrome
HIV Infection Is Associated with Greater Left Ventricular Mass in the Multicenter AIDS Cohort Study.
Acquired Immunodeficiency Syndrome
HIV protease inhibitors as new treatment options for Kaposi's sarcoma.
Acquired Immunodeficiency Syndrome
HIV protease inhibitors inhibit FACE1/ZMPSTE24: a mechanism for acquired lipodystrophy in patients on highly active antiretroviral therapy?
Acquired Immunodeficiency Syndrome
HIV protease inhibitors: a review of molecular selectivity and toxicity.
Acquired Immunodeficiency Syndrome
HIV RNA and CD4 cell count response to protease inhibitor therapy in an urban AIDS clinic: response to both initial and salvage therapy.
Acquired Immunodeficiency Syndrome
HIV-1 integrase inhibitors: a decade of research and two drugs in clinical trial.
Acquired Immunodeficiency Syndrome
HIV-1 NCp7 as a target for the design of novel antiviral agents.
Acquired Immunodeficiency Syndrome
HIV-1 PROTEASE SUBSTRATE CO-EVOLUTION IN NELFINAVIR RESISTANCE.
Acquired Immunodeficiency Syndrome
HIV-1-resistant strains during 8-week on 8-week off intermittent therapy and their effect on CD4+ T-cell counts and antiviral response.
Acquired Immunodeficiency Syndrome
HIV-Protease inhibitors reduce cell adherence of Candida albicans strains by inhibition of yeast secreted aspartic proteases.
Acquired Immunodeficiency Syndrome
HIV-related lipodystrophy: a clinical syndrome with implications for nursing practice.
Acquired Immunodeficiency Syndrome
HIV-related morbidity and mortality in patients starting protease inhibitors in very advanced HIV disease (CD4 count of < 50 cells/microL): an analysis of 338 clinical events from a randomized clinical trial.
Acquired Immunodeficiency Syndrome
HIVcleave: a web-server for predicting human immunodeficiency virus protease cleavage sites in proteins.
Acquired Immunodeficiency Syndrome
Homology modeling and molecular interaction field studies of alpha-glucosidases as a guide to structure-based design of novel proposed anti-HIV inhibitors.
Acquired Immunodeficiency Syndrome
How Mutations Can Resist Drug Binding yet Keep HIV-1 Protease Functional.
Acquired Immunodeficiency Syndrome
How to prolong the effects of combination therapy for HIV.
Acquired Immunodeficiency Syndrome
Hyperlipidaemia a risk factor for femoral head osteonecrosis (Legg-Calv -Perthes-like disease) in children with AIDS: case report.
Acquired Immunodeficiency Syndrome
Identification of inhibitors of the HIV-1 gp41 six-helix bundle formation from extracts of Chinese medicinal herbs Prunella vulgaris and Rhizoma cibotte.
Acquired Immunodeficiency Syndrome
Identification of new genotypic cut-off levels to predict the efficacy of lopinavir/ritonavir and darunavir/ritonavir in the TITAN trial.
Acquired Immunodeficiency Syndrome
Illinois cancels 82 AIDS drugs to pay for one protease inhibitor.
Acquired Immunodeficiency Syndrome
Imaging of Mycobacterium avium-intracellulare infection in AIDS patients on highly active antiretroviral therapy: reversal syndrome.
Acquired Immunodeficiency Syndrome
Immunologic effects of combined protease inhibitor and reverse transcriptase inhibitor therapy in previously treated chronic HIV-1 infection.
Acquired Immunodeficiency Syndrome
Impact of new developments in antiretroviral treatment on AIDS prevention and care in resource-poor countries.
Acquired Immunodeficiency Syndrome
Impact of PI and NNRTI HAART-based therapy on oral lesions of Brazilian HIV-infected patients.
Acquired Immunodeficiency Syndrome
Impact of protease inhibitors and other antiretroviral treatments on acquired immunodeficiency syndrome survival in San Francisco, California, 1987-1996.
Acquired Immunodeficiency Syndrome
Impact of protease inhibitors on AIDS-defining events and hospitalizations in 10 French AIDS reference centres. Fédération National des Centres de Lutte contre le SIDA.
Acquired Immunodeficiency Syndrome
Implications of HIV treatment advances for behavioral research on AIDS: protease inhibitors and new challenges in HIV secondary prevention.
Acquired Immunodeficiency Syndrome
Improved outcome of cytomegalovirus retinitis in AIDS patients after introduction of protease inhibitors.
Acquired Immunodeficiency Syndrome
Improved prognosis in patients with acquired immunodeficiency syndrome-related lymphoma.
Acquired Immunodeficiency Syndrome
Improved survival among HIV-infected patients after initiation of triple-drug antiretroviral regimens.
Acquired Immunodeficiency Syndrome
In vitro inhibition of human immunodeficiency virus type 1 by a combination of delavirdine (U-90152) with protease inhibitor U-75875 or interferon-alpha.
Acquired Immunodeficiency Syndrome
In vitro selection and characterization of human immunodeficiency virus type 1 variants with increased resistance to ABT-378, a novel protease inhibitor.
Acquired Immunodeficiency Syndrome
Inhibition of human immunodeficiency virus-1 protease by a C2-symmetric phosphinate. Synthesis and crystallographic analysis.
Acquired Immunodeficiency Syndrome
Inhibition Profiling of Retroviral Protease Inhibitors Using an HIV-2 Modular System.
Acquired Immunodeficiency Syndrome
Inhibitors of HIV-1 reverse transcriptase and integrase: classical and emerging therapeutical approaches.
Acquired Immunodeficiency Syndrome
Insertions and deletions in HIV-1 reverse transcriptase: consequences for drug resistance and viral fitness.
Acquired Immunodeficiency Syndrome
Interferon-alpha2b With Protease Inhibitor-Based Antiretroviral Therapy in Patients With AIDS-Associated Kaposi Sarcoma: An AIDS Malignancy Consortium Phase I Trial.
Acquired Immunodeficiency Syndrome
Investigation of oral bioavailability and brain distribution of the Ind(8)-Val conjugate of indinavir in rodents.
Acquired Immunodeficiency Syndrome
Involvement of HIV-1 protease in virus-induced cell killing.
Acquired Immunodeficiency Syndrome
Issues in the treatment of active tuberculosis in human immunodeficiency virus-infected patients.
Acquired Immunodeficiency Syndrome
Kaposi's sarcoma and non-Hodgkin's lymphoma incidence trends in AIDS Clinical Trial Group study participants.
Acquired Immunodeficiency Syndrome
L-chicoric acid, an inhibitor of human immunodeficiency virus type 1 (HIV-1) integrase, improves on the in vitro anti-HIV-1 effect of Zidovudine plus a protease inhibitor (AG1350).
Acquired Immunodeficiency Syndrome
Lack of reactivation of cytomegalovirus (CMV) retinitis after stopping CMV maintenance therapy in AIDS patients with sustained elevations in CD4 T cells in response to highly active antiretroviral therapy.
Acquired Immunodeficiency Syndrome
LC determination of indinavir in biological matrices with electrochemical detection.
Acquired Immunodeficiency Syndrome
Leisure time physical activity prevents accumulation of central fat in HIV/AIDS subjects on highly active antiretroviral therapy.
Acquired Immunodeficiency Syndrome
Lipemia retinalis in acquired immunodeficiency syndrome treated with protease inhibitors.
Acquired Immunodeficiency Syndrome
Lipid abnormalities in a healthcare worker receiving HIV prophylaxis.
Acquired Immunodeficiency Syndrome
Lipid Architectonics for Superior Oral Bioavailability of Nelfinavir Mesylate: Comparative in vitro and in vivo Assessment.
Acquired Immunodeficiency Syndrome
Locally Efficient Estimation of Marginal Treatment Effects When Outcomes Are Correlated: Is the Prize Worth the Chase?
Acquired Immunodeficiency Syndrome
Long-lasting remission of cytomegalovirus retinitis without maintenance therapy in human immunodeficiency virus-infected patients.
Acquired Immunodeficiency Syndrome
Long-term cardiovascular risk with protease inhibitors and management of the dyslipidemia.
Acquired Immunodeficiency Syndrome
Long-term protease inhibitor-containing therapy results in limited improvement in T cell function but not restoration of interleukin-12 production in pediatric patients with AIDS.
Acquired Immunodeficiency Syndrome
Long-term weight gain after initiating combination antiretroviral therapy in treatment-naïve Asian people living with human immunodeficiency virus.
Acquired Immunodeficiency Syndrome
LOSS OF DARUNAVIR'S PROTEASE DIMERIZATION INHIBITION ACTIVITY IS ASSOCIATED WITH HIV-1 ACQUISITION OF RESISTANCE TO DARUNAVIR.
Acquired Immunodeficiency Syndrome
Mapping of the active site of proteases in the 1960s and rational design of inhibitors/drugs in the 1990s.
Acquired Immunodeficiency Syndrome
Metabolic Abnormalities Associated with the Use of Protease Inhibitors and Non-nucleoside Reverse Transcriptase Inhibitors.
Acquired Immunodeficiency Syndrome
Metabolic dysfunctions in non-antiretroviral treated HIV/AIDS patients.
Acquired Immunodeficiency Syndrome
Metabolic effects associated to the highly active antiretroviral therapy (HAART) in AIDS patients.
Acquired Immunodeficiency Syndrome
Micellar electrokinetic chromatography method development for determination of impurities in Ritonavir.
Acquired Immunodeficiency Syndrome
Microbial conversion of indene to indandiol: a key intermediate in the synthesis of CRIXIVAN.
Acquired Immunodeficiency Syndrome
Minireview: weapons of lean body mass destruction: the role of ectopic lipids in the metabolic syndrome.
Acquired Immunodeficiency Syndrome
Model for simulation of HIV/AIDS and cost-effectiveness of preventing non-tuberculous mycobacterial (MAC)-disease.
Acquired Immunodeficiency Syndrome
Model system for high-throughput screening of novel human immunodeficiency virus protease inhibitors in Escherichia coli.
Acquired Immunodeficiency Syndrome
Modern diets and diseases: NO-zinc balance. Under Th1, zinc and nitrogen monoxide (NO) collectively protect against viruses, AIDS, autoimmunity, diabetes, allergies, asthma, infectious diseases, atherosclerosis and cancer.
Acquired Immunodeficiency Syndrome
Molecular Characteristics of HIV Type 1 Infection Among Prisoners from Central Western Brazil.
Acquired Immunodeficiency Syndrome
Multimorbidity among people with HIV in regional New South Wales, Australia.
Acquired Immunodeficiency Syndrome
Multiple drug class-wide resistance associated with poorer survival after treatment failure in a cohort of HIV-infected patients.
Acquired Immunodeficiency Syndrome
Newly approved integrase inhibitors for clinical treatment of AIDS.
Acquired Immunodeficiency Syndrome
Non-active site changes elicit broad-based cross-resistance of the HIV-1 protease to inhibitors.
Acquired Immunodeficiency Syndrome
Nonprogressive CMV retinitis in AIDS patients with protease inhibitors therapy for AIDS.
Acquired Immunodeficiency Syndrome
Novel fluorogenic substrates for assaying retroviral proteases by resonance energy transfer.
Acquired Immunodeficiency Syndrome
Novel innate immune functions of the whey acidic protein family.
Acquired Immunodeficiency Syndrome
On the role of the R configuration of the reaction-intermediate isostere in HIV-1 protease-inhibitor binding: X-ray structure at 2.0 A resolution.
Acquired Immunodeficiency Syndrome
Optimized dialysis and protease inhibition of sputum dithiothreitol supernatants.
Acquired Immunodeficiency Syndrome
Oral and dental care and treatment protocols for the management of HIV-infected patients.
Acquired Immunodeficiency Syndrome
Osteopenia in HIV-infected women prior to highly active antiretroviral therapy.
Acquired Immunodeficiency Syndrome
Overcoming drug resistance in HIV-1 chemotherapy: the binding thermodynamics of Amprenavir and TMC-126 to wild-type and drug-resistant mutants of the HIV-1 protease.
Acquired Immunodeficiency Syndrome
Oxidized lipoproteins are associated with markers of inflammation andimmune activation in HIV-1 infection.
Acquired Immunodeficiency Syndrome
Partial purification and substrate analysis of bacterially expressed HIV protease by means of monoclonal antibody.
Acquired Immunodeficiency Syndrome
Peptide inhibition of HIV-1: current status and future potential.
Acquired Immunodeficiency Syndrome
Peptidomimetic therapeutic agents targeting the protease enzyme of the human immunodeficiency virus and hepatitis C virus.
Acquired Immunodeficiency Syndrome
Pharmacokinetic interaction between ritonavir and clarithromycin.
Acquired Immunodeficiency Syndrome
Pilot study evaluating the interaction between paclitaxel and protease inhibitors in patients with human immunodeficiency virus-associated Kaposi's sarcoma: an Eastern Cooperative Oncology Group (ECOG) and AIDS Malignancy Consortium (AMC) trial.
Acquired Immunodeficiency Syndrome
Population pharmacokinetics and pharmacodynamics of efavirenz, nelfinavir, and indinavir: Adult AIDS Clinical Trial Group Study 398.
Acquired Immunodeficiency Syndrome
Positive impact of protease inhibitors on body composition and energy expenditure in HIV-infected and AIDS patients.
Acquired Immunodeficiency Syndrome
Positive selection detection in 40,000 human immunodeficiency virus (HIV) type 1 sequences automatically identifies drug resistance and positive fitness mutations in HIV protease and reverse transcriptase.
Acquired Immunodeficiency Syndrome
Potential of carbohydrate-binding agents as therapeutics against enveloped viruses.
Acquired Immunodeficiency Syndrome
Prediction of HIV-1 protease inhibitory activity of 4-hydroxy-5,6-dihydropyran-2-ones: QSAR study.
Acquired Immunodeficiency Syndrome
Predictive factors of renal impairment in HIV-infected patients on antiretroviral therapy: Results from the VACH longitudinal cohort study.
Acquired Immunodeficiency Syndrome
Prevalence and pattern of drug resistance mutations among antiretroviral-treated HIV-1 patients with suboptimal virological response in Malaysia.
Acquired Immunodeficiency Syndrome
Prevalence and Risk Factors for Significant Liver Fibrosis in Patients with HIV Infection.
Acquired Immunodeficiency Syndrome
Prevalence of factor V Leiden in a population of patients with congenital heart disease.
Acquired Immunodeficiency Syndrome
Prevalence of resistance mutations in antiretroviral-naive chronically HIV-infected patients in 1998: a French nationwide study.
Acquired Immunodeficiency Syndrome
Progression to AIDS or death as endpoints in HIV clinical trials.
Acquired Immunodeficiency Syndrome
Protease gene structure and env gene variability of the AIDS virus.
Acquired Immunodeficiency Syndrome
Protease inhibitor and triple-drug therapy: cellular immune parameters are not restored in pediatric AIDS patients after 6 months of treatment.
Acquired Immunodeficiency Syndrome
Protease inhibitor combination therapies and perceptions of gay men regarding AIDS severity and the need to maintain safer sex.
Acquired Immunodeficiency Syndrome
Protease inhibitor effects on triglyceride synthesis and adipokine secretion in human omental and subcutaneous adipose tissue.
Acquired Immunodeficiency Syndrome
Protease inhibitor resistance analysis in the MONARK trial comparing first-line lopinavir-ritonavir monotherapy to lopinavir-ritonavir plus zidovudine and lamivudine triple therapy.
Acquired Immunodeficiency Syndrome
Protease inhibitor therapy is associated with markedly prolonged time to relapse and improved survival in AIDS patients with cytomegalovirus retinitis.
Acquired Immunodeficiency Syndrome
Protease inhibitor use among a community sample of people with HIV disease.
Acquired Immunodeficiency Syndrome
Protease inhibitor-based antiretroviral therapy and glucose tolerance in pregnancy: AIDS Clinical Trials Group A5084.
Acquired Immunodeficiency Syndrome
Protease inhibitors as potential therapeutic agents for AIDS.
Acquired Immunodeficiency Syndrome
Protease inhibitors: changing the way AIDS case management does business.
Acquired Immunodeficiency Syndrome
Protease released from sea urchin eggs at fertilization alters the vitelline layer and aids in preventing polyspermy.
Acquired Immunodeficiency Syndrome
QSAR studies on HIV-1 protease inhibitors using non-linearly transformed descriptors.
Acquired Immunodeficiency Syndrome
Race/Ethnicity and Protease Inhibitor Use Influence Plasma Tenofovir Exposure in Adults Living with HIV-1 in AIDS Clinical Trials Group Study A5202.
Acquired Immunodeficiency Syndrome
Rates of disease progression according to initial highly active antiretroviral therapy regimen: a collaborative analysis of 12 prospective cohort studies.
Acquired Immunodeficiency Syndrome
Rates of disease progression by baseline CD4 cell count and viral load after initiating triple-drug therapy.
Acquired Immunodeficiency Syndrome
Rational approach to AIDS drug design through structural biology.
Acquired Immunodeficiency Syndrome
Reappraisal of the aetiology and prognostic factors of severe acute respiratory failure in HIV patients.
Acquired Immunodeficiency Syndrome
Recent progress in the development of inhibitors of human immunodeficiency virus (hiv) integrase for the management of hiv infection.
Acquired Immunodeficiency Syndrome
Recovery of the wild type atomic flexibility in the HIV-1 protease double mutants.
Acquired Immunodeficiency Syndrome
Reduction in hospitalization costs, morbidity, disability, and mortality in patients with aids treated with protease inhibitors.
Acquired Immunodeficiency Syndrome
Regression of cytomegalovirus retinitis associated with protease-inhibitor treatment in patients with AIDS.
Acquired Immunodeficiency Syndrome
Regression of HIV encephalopathy and basal ganglia signal intensity abnormality at MR imaging in patients with AIDS after the initiation of protease inhibitor therapy.
Acquired Immunodeficiency Syndrome
Relative preservation of natural killer cell cytotoxicity and number in healthy AIDS patients with low CD4 cell counts.
Acquired Immunodeficiency Syndrome
Resistance of HIV-1 to multiple antiretroviral drugs in France: a 6-year survey (1997-2002) based on an analysis of over 7000 genotypes.
Acquired Immunodeficiency Syndrome
Resistance profiles of cyclic and linear inhibitors of HIV-1 protease.
Acquired Immunodeficiency Syndrome
Resolution of Kaposi's sarcoma associated with undetectable level of human herpesvirus 8 DNA in a patient with AIDS after protease inhibitor therapy.
Acquired Immunodeficiency Syndrome
Restructuring life to face the future: the perspective of men after a positive response to protease inhibitor therapy.
Acquired Immunodeficiency Syndrome
Review: thromboses among HIV-infected patients during the highly active antiretroviral therapy era.
Acquired Immunodeficiency Syndrome
Ritonavir (Abbott protease inhibitor) proves survival benefit in late-stage AIDS.
Acquired Immunodeficiency Syndrome
Role of protease inhibitors and acylation stimulating protein in the adipogenesis in 3T3-L1 cells.
Acquired Immunodeficiency Syndrome
Scutellaria baicalensis and a constituent flavonoid, baicalein, attenuate ritonavir-induced gastrointestinal side-effects.
Acquired Immunodeficiency Syndrome
Secretases as therapeutic targets for Alzheimer's disease.
Acquired Immunodeficiency Syndrome
Self-reported antiretroviral therapy in injection drug users.
Acquired Immunodeficiency Syndrome
Sensitive and simultaneous determination of HIV protease inhibitors in rat biological samples by liquid chromatography-mass spectrometry.
Acquired Immunodeficiency Syndrome
Sexual transmission of HIV-1 isolate showing G-->A hypermutation.
Acquired Immunodeficiency Syndrome
Short Communication: Low Prevalence of Genotypic Drug Resistance Mutations among Antiretroviral-Naive HIV Type 1 Patients in Malaysia.
Acquired Immunodeficiency Syndrome
Simple and rapid high-performance liquid chromatographic method for nelfinavir, M8 nelfinavir metabolite, ritonavir and saquinavir assay in plasma.
Acquired Immunodeficiency Syndrome
Simple high-performance liquid chromatographic determination of the protease inhibitor indinavir in human plasma.
Acquired Immunodeficiency Syndrome
Single-dose pharmacokinetics of indinavir and the effect of food.
Acquired Immunodeficiency Syndrome
Site-directed mutagenesis of the P2 residue of human antithrombin.
Acquired Immunodeficiency Syndrome
Ste24: An Integral Membrane Protein Zinc Metalloprotease with Provocative Structure and Emergent Biology.
Acquired Immunodeficiency Syndrome
Structure of HOE/BAY 793 complexed to human immunodeficiency virus (HIV-1) protease in two different crystal forms--structure/function relationship and influence of crystal packing.
Acquired Immunodeficiency Syndrome
Structure-assisted design of nonpeptide human immunodeficiency virus-1 protease inhibitors.
Acquired Immunodeficiency Syndrome
Structure-based design of AIDS drugs and the development of resistance.
Acquired Immunodeficiency Syndrome
Structure-based design of symmetric inhibitors of HIV-1 protease.
Acquired Immunodeficiency Syndrome
Studies on the characterization and polymorphic stability of Fosamprenavir.
Acquired Immunodeficiency Syndrome
Subtype polymorphisms among HIV-1 protease variants confer altered flap conformations and flexibility.
Acquired Immunodeficiency Syndrome
Surveillance of HIV drug resistance in children receiving antiretroviral therapy: a pilot study of the World Health Organization's generic protocol in Maputo, Mozambique.
Acquired Immunodeficiency Syndrome
Survival after diagnosis of AIDS among adults resident in the United Kingdom in the era of multiple therapies.
Acquired Immunodeficiency Syndrome
Survival of AIDS patients in Croatia prior to the introduction of combined antiretroviral therapy with protease inhibitors.
Acquired Immunodeficiency Syndrome
Survival time of AIDS patients in Bamrasnaradura Institute.
Acquired Immunodeficiency Syndrome
Synergistic binding of inhibitors to the protease from HIV type 1.
Acquired Immunodeficiency Syndrome
Targeting cysteine residues of human immunodeficiency virus type 1 protease by reactive free radical species.
Acquired Immunodeficiency Syndrome
Targeting HIV: antiretroviral therapy and development of drug resistance.
Acquired Immunodeficiency Syndrome
The AIDS autopsy spleen: a comparison of the pre-anti-retroviral and highly active anti-retroviral therapy eras.
Acquired Immunodeficiency Syndrome
The Anti-Cancer Properties of the HIV Protease Inhibitor Nelfinavir.
Acquired Immunodeficiency Syndrome
The Continuing Evolution of HIV-1 Therapy: Identification and Development of Novel Antiretroviral Agents Targeting Viral and Cellular Targets.
Acquired Immunodeficiency Syndrome
The crystal structure of an essential high-temperature requirement protein HtrA1 (Rv1223) from Mycobacterium tuberculosis reveals its unique features.
Acquired Immunodeficiency Syndrome
The Current Recommended Drugs and Strategies for the Treatment of Coronavirus Disease (COVID-19).
Acquired Immunodeficiency Syndrome
The dangerous financial politics of AIDS "cocktail" therapies.
Acquired Immunodeficiency Syndrome
The design and implementation of A5146, a prospective trial assessing the utility of therapeutic drug monitoring using an inhibitory quotient in antiretroviral-experienced HIV-infected patients.
Acquired Immunodeficiency Syndrome
The effect of treatment with a protease inhibitor on mycobacterial infection.
Acquired Immunodeficiency Syndrome
The failure of HAART to cure the HIV-1/AIDS complex. Suggestions to add integrase inhibitors as complementary virostatics, and to replace their continuous long combination applications by short sequences differing by drug rotations.
Acquired Immunodeficiency Syndrome
The human immunodeficiency virus (HIV) protease inhibitor indinavir directly affects the opportunistic fungal pathogen Cryptococcus neoformans.
Acquired Immunodeficiency Syndrome
The impact of Hayward green kiwifruit on dietary protein digestion and protein metabolism.
Acquired Immunodeficiency Syndrome
The insulin-like growth factor system in human immunodeficiency virus infection: relations to immunological parameters, disease progression, and antiretroviral therapy.
Acquired Immunodeficiency Syndrome
The urological management of the patient with acquired immunodeficiency syndrome.
Acquired Immunodeficiency Syndrome
The use of highly active antiretroviral therapy (HAART) in patients with advanced HIV infection: impact on medical, palliative care, and quality of life outcomes.
Acquired Immunodeficiency Syndrome
The yeast HtrA orthologue Ynm3 is a protease with chaperone activity that aids survival under heat stress.
Acquired Immunodeficiency Syndrome
Thermal stability and hydration behavior of ritonavir sulfate: A vibrational spectroscopic approach.
Acquired Immunodeficiency Syndrome
Three-year clinical outcomes of resistance genotyping and expert advice: extended follow-up of the Argenta trial.
Acquired Immunodeficiency Syndrome
Time on antiretroviral therapy is a protective factor for liver fibrosis in HIV and hepatitis C virus (HCV) co-infected patients.
Acquired Immunodeficiency Syndrome
Time to AIDS from 1992 to 1999 in HIV-1-infected subjects with known date of infection.
Acquired Immunodeficiency Syndrome
Transient vitreous inflammatory reactions associated with combination antiretroviral therapy in patients with AIDS and cytomegalovirus retinitis.
Acquired Immunodeficiency Syndrome
Treatment history and baseline viral load, but not viral tropism or CCR-5 genotype, influence prolonged antiviral efficacy of highly active antiretroviral treatment.
Acquired Immunodeficiency Syndrome
Trends of AIDS in Guadeloupe (French West Indies) a longitudinal survey from 1988 to 1997.
Acquired Immunodeficiency Syndrome
Trimethoprim-sulfamethoxazole (TMP/SMX) potentiates indinavir nephrotoxicity.
Acquired Immunodeficiency Syndrome
Triple-class antiretroviral drug resistance: risk and predictors among HIV-1-infected patients.
Acquired Immunodeficiency Syndrome
Two orthogonal approaches to overcome multi-drug resistant HIV-1s: development of protease inhibitors and entry inhibitors based on CXCR4 antagonists.
Acquired Immunodeficiency Syndrome
Understanding the basis of I50V-induced affinity decrease in HIV-1 protease via molecular dynamics simulations using polarized force field.
Acquired Immunodeficiency Syndrome
Unfolding kinetics of tryptophan side chains in the dimerization and hinge regions of HIV-I protease tethered dimer by real time NMR spectroscopy.
Acquired Immunodeficiency Syndrome
US cost effectiveness of darunavir/ritonavir 600/100 mg bid in treatment-experienced, HIV-infected adults with evidence of protease inhibitor resistance included in the TITAN Trial.
Acquired Immunodeficiency Syndrome
Use of observational databases to evaluate the effectiveness of antiretroviral therapy for HIV infection: comparison of cohort studies with randomized trials. EuroSIDA, the French Hospital Database on HIV and the Swiss HIV Cohort Study Groups.
Acquired Immunodeficiency Syndrome
Use of protease inhibitors among persons with AIDS in Los Angeles County.
Acquired Immunodeficiency Syndrome
Use of protease inhibitors and non-nucleoside reverse transcriptase inhibitors among Medicaid beneficiaries with AIDS.
Acquired Immunodeficiency Syndrome
Usefulness of route of transmission, absolute CD8+ T-cell counts, and levels of serum tumor necrosis factor alpha as predictors of survival of HIV-1-infected patients with very low CD4 + T-cell counts.
Acquired Immunodeficiency Syndrome
Uveitis following administration of the protease inhibitor indinavir to a patient with AIDS.
Acquired Immunodeficiency Syndrome
Vasodilator agents protect against indinavir nephrotoxicity.
Acquired Immunodeficiency Syndrome
Viral and immunologic follow up of 4 to 9 years of AIDS treatments by quadruple combinations of virostatics including integrase inhibitors applied in short sequences differing by drug rotation.
Acquired Immunodeficiency Syndrome
Viral load outcome of non-nucleoside reverse transcriptase inhibitor regimens for 2203 mainly antiretroviral-experienced patients.
Acquired Immunodeficiency Syndrome
Virological responses to atazanavir-ritonavir-based regimens: resistance-substitutions score and pharmacokinetic parameters (Reyaphar study).
Acquired Immunodeficiency Syndrome
Virological responses to lamivudine or emtricitabine when combined with tenofovir and a protease inhibitor in treatment-naïve HIV-1-infected patients in the Dutch AIDS Therapy Evaluation in the Netherlands (ATHENA) cohort.
Acquired Immunodeficiency Syndrome
Visceral adiposity, C-peptide levels, and low lipase activities predict HIV-dyslipidemia.
Acquired Immunodeficiency Syndrome
[Acute myocardial infarct in HIV-positive patients in treatment with protease inhibitors]
Acquired Immunodeficiency Syndrome
[An important point of attach in AIDS treatment. HIV protease inhibitors: state of the art]
Acquired Immunodeficiency Syndrome
[Attitude of the clinican toward adverse effects of protease inhibitors]
Acquired Immunodeficiency Syndrome
[Control of the AIDS virus. The protease inhibitor Saquinavir apparently controls the disease course significantly and decreases death rate]
Acquired Immunodeficiency Syndrome
[Course of cytomegalovirus retinitis in HIV positive patients treated with triple antiretroviral therapy]
Acquired Immunodeficiency Syndrome
[Evolution of AIDS survival in Spain: effect of the inclusion of pulmonary tuberculosis for case definition in the protease inhibitors era]
Acquired Immunodeficiency Syndrome
[Factors associated with an abnormal ankle-braquial index in a cohort of patients with HIV-1 infection.]
Acquired Immunodeficiency Syndrome
[Factors predictive of early virologic response after a first treatment with an protease inhibitor in the course of HIV infection]
Acquired Immunodeficiency Syndrome
[Genes participating in the maturation of AIDS viruses; retrovirus protease]
Acquired Immunodeficiency Syndrome
[Genotypic antiretroviral resistance testing and phylogenetic analysis of protease and reverse transcriptase in antiretroviral drug-naïve AIDS patients in Henan province]
Acquired Immunodeficiency Syndrome
[Granular lymphocyte-proliferative disorder following initiation of protease inhibitor therapy in a patient with acquired immunodeficiency syndrome]
Acquired Immunodeficiency Syndrome
[HIV protease inhibitors (new possibilities in the treatment of HIV infection and AIDS)]
Acquired Immunodeficiency Syndrome
[Human immunodeficiency virus infection: physiopathological approach to specific therapeutic strategies]
Acquired Immunodeficiency Syndrome
[Impact of anti-retroviral treatment with protease inhibitors on the evolution of cytomegalovirus retinitis in the patient carrying acquired immunodeficiency syndrome]
Acquired Immunodeficiency Syndrome
[Inhibitors of HIV-1 reverse transcriptase and protease as chemotherapeutics for AIDS]
Acquired Immunodeficiency Syndrome
[Initial administration of a protease inhibitor delays the progression of AIDS by half time]
Acquired Immunodeficiency Syndrome
[Modern methods of detection of HIV resistance to the action of anti-retroviral agents]
Acquired Immunodeficiency Syndrome
[Molecular modeling in the battle against AIDS. Drugs design in the development of substrate-like HIV protease inhibitors]
Acquired Immunodeficiency Syndrome
[New AIDS study confirms: triple combination therapy with the protease inhibitor indinavir lowers the risk of mortality by 50%]
Acquired Immunodeficiency Syndrome
[Protease inhibitor Kaletra (Lopinavir/Ritonavir): significance and role in antiretroviral therapy of HIV infection and AIDS]
Acquired Immunodeficiency Syndrome
[Pulmonary thromboembolism in HIV infected admitted patients under 50 years old.]
Acquired Immunodeficiency Syndrome
[Recent development of novel reverse transcriptase inhibitors and protease inhibitors against HIV-1 infection]
Acquired Immunodeficiency Syndrome
[Survival of patients with AIDS treated with protease inhibitors]
Acquired Immunodeficiency Syndrome
[Treatment of HIV infections and AIDS with protease inhibitor and two nucleoside analogs]
ACTH-Secreting Pituitary Adenoma
Inhibition of Ubiquitin-specific Peptidase 8 Suppresses Adrenocorticotropic Hormone Production and Tumorous Corticotroph Cell Growth in AtT20 Cells.
ACTH-Secreting Pituitary Adenoma
Lack of Ubiquitin Specific Protease 8 (USP8) Mutations in Canine Corticotroph Pituitary Adenomas.
ACTH-Secreting Pituitary Adenoma
Recent advances in understanding corticotroph pituitary tumor initiation and progression.
ACTH-Secreting Pituitary Adenoma
The Immune Profile of Pituitary Adenomas and a Novel Immune Classification for Predicting Immunotherapy Responsiveness.
Acute Coronary Syndrome
Acute Coronary Syndromes in Treatment-Naïve Black South Africans with Human Immunodeficiency Virus Infection.
Acute Coronary Syndrome
Effect of PCSK9 E670G and R46L Polymorphisms on Major Adverse Cardio-Cerebrovascular Events in Patients with ST-Segment Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention.
Acute Coronary Syndrome
Effects of genetic variation in protease activated receptor 4 after an acute coronary syndrome: Analysis from the TRACER trial.
Acute Coronary Syndrome
Human neutrophil elastase: mediator and therapeutic target in atherosclerosis.
Acute Coronary Syndrome
Protease activated receptor-1 (PAR-1) mediated platelet aggregation is dependant on clopidogrel response.
Acute Coronary Syndrome
[Correlation of serum ADAMTS13 and TSP1 levels with myocardial injury and prognosis in patients with acute coronary syndrome].
Acute Coronary Syndrome
[The frequency of allelic polymorphism of genes encoding immunoproteasome catalytic subunits in acute coronary syndrome patients]
Acute Generalized Exanthematous Pustulosis
Acute generalized exanthematous pustulosis: a cutaneous adverse effect due to prophylactic antiviral therapy with protease inhibitor.
Acute Generalized Exanthematous Pustulosis
Life-threatening acute generalized exanthematous pustulosis induced by two different protease inhibitors in an HIV-1-infected patient.
Acute Kidney Injury
Evidence for intrarenal kallikrein storage during chromate-induced acute renal failure in rat.
Acute Kidney Injury
Evidence for the participation of proteases on protein catabolism during hypercatabolic renal failure.
Acute Kidney Injury
Hemolytic uremic syndrome-associated Shiga toxins promote endothelial-cell secretion and impair ADAMTS13 cleavage of unusually large von Willebrand factor multimers.
Acute Kidney Injury
Heparin-binding protein as a novel biomarker for sepsis-related acute kidney injury.
Acute Kidney Injury
Lysosomal protease cathepsin D; a new driver of apoptosis during acute kidney injury.
Acute Kidney Injury
Omi/HtrA2 protease is associated with tubular cell apoptosis and fibrosis induced by unilateral ureteral obstruction.
Acute Kidney Injury
Renal effects of the serine protease inhibitor aprotinin in healthy conscious mice.
Acute Kidney Injury
Secretory Leukocyte Protease Inhibitor (SLPI)-A Novel Predictive Biomarker of Acute Kidney Injury after Cardiac Surgery: A Prospective Observational Study.
Acute Kidney Injury
[Pathophysiological mechanism of ischemic acute renal failure: protective effect of coenzyme Q10, Ca channel blocker, superoxide dismutase and protease inhibitor against ischemic acute renal failure]
Acute Kidney Injury
[Protective effect of recombinant adult serine protease inhibitor from Trichinella spiralis on sepsis-associated acute kidney injury in mice].
Acute Lung Injury
Activity-based Near-Infrared Fluorogenic Probe Enables In Vitro and In Vivo Profiling of Neutrophil Elastase.
Acute Lung Injury
Acute lung injury induced by whole gastric fluid: hepatic acute phase response contributes to increase lung antiprotease protection.
Acute Lung Injury
Antithrombin plus alpha-1 protease inhibitor does not affect coagulation and inflammation in two murine models of acute lung injury.
Acute Lung Injury
Calpain inhibition ameliorates scald burn-induced acute lung injury in rats.
Acute Lung Injury
Detection of human neutrophil elastase by aptamer affinity capillary electrophoresis coupled with laser-induced fluorescence using specified site fluorescently labeled aptamer.
Acute Lung Injury
Evidence of increased matrix metalloproteinase-9 concentration in patients following cardiopulmonary bypass.
Acute Lung Injury
Functions of pulmonary epithelial integrins: from development to disease.
Acute Lung Injury
Hypothesis: Alpha-1-antitrypsin is a promising treatment option for COVID-19.
Acute Lung Injury
Inhibition of NF-kappaB activation and augmentation of IkappaBbeta by secretory leukocyte protease inhibitor during lung inflammation.
Acute Lung Injury
Lard-based high-fat diet increases secretory leukocyte protease inhibitor expression and attenuates the inflammatory response of acute lung injury in endotoxemic rats.
Acute Lung Injury
N-Arylacyl O-sulfonated aminoglycosides as novel inhibitors of human neutrophil elastase, cathepsin G and proteinase 3.
Acute Lung Injury
Neutrophil proteinases in hydrochloric acid- and endotoxin-induced acute lung injury: evaluation of interstitial protease activity by in situ zymography.
Acute Lung Injury
Role of protease activated receptor 2 in experimental acute lung injury and lung fibrosis.
Acute Lung Injury
Serine protease inhibitor MDSPI16 ameliorates LPS-induced acute lung injury through its anti-inflammatory activity.
Acute Lung Injury
The Protective Effects of Protease Inhibitor MG-132 on Sepsis-Induced Acute Lung Rats and Its Possible Mechanisms.
Acute Lung Injury
Tissue factor-dependent coagulation protease signaling in acute lung injury.
Acute Lung Injury
Ulinastatin post-treatment attenuates lipopolysaccharide-induced acute lung injury in rats and human alveolar epithelial cells.
Acute Lung Injury
[Experimental study on effect and mechanism of soybean protease inhibitor on endotoxin-induced acute lung injury]
Acute Lung Injury
[Inhibitory effects of protease inhibitor on endotoxin-induced acute lung injury in rats]
Acute Lung Injury
[Pharmacological profile of a specific neutrophil elastase inhibitor, Sivelestat sodium hydrate]
Acute Lung Injury
[Protective effect of a protease inhibitor on acute lung injury after hepatic ischemia/reperfusion in the rat]
adam 17 endopeptidase deficiency
Structural and Functional Analyses of the Shedding Protease ADAM17 in HoxB8-Immortalized Macrophages and Dendritic-like Cells.
adamts13 endopeptidase deficiency
An update on pathogenesis and diagnosis of thrombotic thrombocytopenic purpura.
adamts13 endopeptidase deficiency
Preserved Expression of mRNA Coding von Willebrand Factor-Cleaving Protease ADAMTS13 by Selenite and Activated Protein C.
adamts13 endopeptidase deficiency
Refractory thrombotic thrombocytopenic purpura associated with oral contraceptives and factor V Leiden: a case report.
adamts13 endopeptidase deficiency
Thrombotic thrombocytopenic purpura: proposal of a new pathogenic mechanism involving Helicobacter pylori infection.
adamts13 endopeptidase deficiency
Von Willebrand factor cleaving protease (ADAMTS-13) in 123 patients with connective tissue diseases (systemic lupus erythematosus and systemic sclerosis).
adamts13 endopeptidase deficiency
von Willebrand factor, von Willebrand factor-cleaving protease, and shear stress.
Adenocarcinoma
A Bowman-Birk inhibitor induces apoptosis in human breast adenocarcinoma through mitochondrial impairment and oxidative damage following proteasome 20S inhibition.
Adenocarcinoma
A serine protease extracted from Trichosanthes kirilowii induces apoptosis via the PI3K/AKT-mediated mitochondrial pathway in human colorectal adenocarcinoma cells.
Adenocarcinoma
Alpha 1-antitrypsin, alpha 1-antichymotrypsin, and alpha 2-macroglobulin in human gastric carcinomas: a retrospective immunohistochemical study.
Adenocarcinoma
Antitumor effects of Nafamostat mesilate on head and neck squamous cell carcinoma.
Adenocarcinoma
Cathepsin B promotes the progression of pancreatic ductal adenocarcinoma in mice.
Adenocarcinoma
Comparative quantitative immunohistochemical and immunoradiometric determinations of cathepsin D in endometrial adenocarcinoma: predictors of tumor aggressiveness.
Adenocarcinoma
Correlation of tumor cytosol cathepsin D with differentiation and invasiveness of endometrial adenocarcinoma.
Adenocarcinoma
Different Cell Cycle Modulation in SKOV-3 Ovarian Cancer Cell Line by Anti-HIV Drugs.
Adenocarcinoma
Differential response of premalignant epithelial cell classes to phorbol ester tumor promoters and to deoxycholic acid.
Adenocarcinoma
Effects of media conditioned by a non-metastasizing human salivary gland adenocarcinoma cell clone and metastasizing clones from salivary gland and various other tissues on the proliferation, migration and protease production of bovine aortic endothelial cells in vitro.
Adenocarcinoma
Epigenetic silencing of the PRSS3 putative tumor suppressor gene in non-small cell lung cancer.
Adenocarcinoma
Expression of the serine protease inhibitor serpinA3 in human colorectal adenocarcinomas.
Adenocarcinoma
Hypoxia augments gelatinase activity in a variety of adenocarcinomas in vitro.
Adenocarcinoma
Immunohistochemical evaluation of tissue-specific proteolytic enzymes in adenomas containing foci of early carcinoma: correlations with cathepsin D expression and other malignant features.
Adenocarcinoma
Inhibition of LONP1 protects against erastin-induced ferroptosis in Pancreatic ductal adenocarcinoma PANC1 cells.
Adenocarcinoma
Inhibitory effect of nafamostat mesilate on metastasis into the livers of mice and on invasion of the extracellular matrix by cancer cells.
Adenocarcinoma
Interleukin-6 increases expression of serine protease inhibitor Kazal type 1 through STAT3 in colorectal adenocarcinoma.
Adenocarcinoma
Involvement of plasminogen activator production with tumor metastasis in a rat model.
Adenocarcinoma
Laminin-111 derived peptides AG73 and C16 regulate invadopodia activity of a human adenoid cystic carcinoma cell line.
Adenocarcinoma
MOC31 immunoreactivity in primary and metastatic carcinoma of the liver. Report of findings and review of other utilized markers.
Adenocarcinoma
Pea (Pisum sativum L.) protease inhibitors from the Bowman-Birk class influence the growth of human colorectal adenocarcinoma HT29 cells in vitro.
Adenocarcinoma
Plasminogen-induced aggregation of PANC-1 cells requires conversion to plasmin and is inhibited by endogenous plasminogen activator inhibitor-1.
Adenocarcinoma
Production and characterization of monoclonal antibody to a 60-kD glycoprotein in ovarian carcinoma.
Adenocarcinoma
Protease inhibitor suppression of colon and anal gland carcinogenesis induced by dimethylhydrazine.
Adenocarcinoma
Re: Protease nexin 1 inhibits hedgehog signaling in prostate adenocarcinoma.
Adenocarcinoma
Serine protease inhibitor Kazal type 1 and epidermal growth factor receptor are expressed in pancreatic tubular adenocarcinoma, intraductal papillary mucinous neoplasm, and pancreatic intraepithelial neoplasia.
Adenocarcinoma
Significance of effector protease receptor-1 expression and its relationship with proliferation and apoptotic index in patients with primary advanced gastric adenocarcinoma.
Adenocarcinoma
Simultaneous fluorescence imaging of protease expression and vascularity during murine colonoscopy for colonic lesion characterization.
Adenocarcinoma
Soybean Bowman-Birk Protease Inhibitor (BBI): Identification of the Mechanisms of BBI Suppressive Effect on Growth of Two Adenocarcinoma Cell Lines: AGS and HT29.
Adenocarcinoma
Stability of the antigen expression in the spontaneous mammary adenocarcinoma during cultivation and absorbtion with immune serum.
Adenocarcinoma
The androgen-regulated type II serine protease TMPRSS2 is differentially expressed and mislocalized in prostate adenocarcinoma.
Adenocarcinoma
The extracellular matrix protein fibronectin is a substrate for kallikrein 7.
Adenocarcinoma
The overexpression of maspin increases the sensitivity of lung adenocarcinoma drug-resistant cells to docetaxel in vitro and in vivo.
Adenocarcinoma
The promoter and the enhancer region of the KLK 3 (prostate specific antigen) gene is frequently mutated in breast tumours and in breast carcinoma cell lines.
Adenocarcinoma
TKP, a serine protease extracted from Trichosanthes kirilowii, inhibits the migration and invasion of colorectal adenocarcinoma cells by targeting Wnt/?-catenin and Hedgehog/Gli1 signalings.
Adenocarcinoma
Ubiquitin-specific protease 14 (USP14) promotes proliferation and metastasis in pancreatic ductal adenocarcinoma.
Adenocarcinoma
[5-fluorouracil inhibits the collagenolytic activity of invasive colonic adenocarcinomas in vitro]
Adenocarcinoma
[Collagenolytic activity of neoplastic and rapidly proliferating normal tissue]
Adenocarcinoma of Lung
Cathepsin A knockdown decreases the proliferation and invasion of A549 lung adenocarcinoma cells.
Adenocarcinoma of Lung
Glucocorticoids regulate arrestin gene expression and redirect the signaling profile of G protein-coupled receptors.
Adenocarcinoma of Lung
HAI-2 as a novel inhibitor of plasmin represses lung cancer cell invasion and metastasis.
Adenocarcinoma of Lung
Integrated analysis reveals candidate genes and transcription factors in lung adenocarcinoma.
Adenocarcinoma of Lung
Stratifin regulates stabilization of receptor tyrosine kinases via interaction with ubiquitin-specific protease 8 in lung adenocarcinoma.
Adenocarcinoma of Lung
Ubiquitin-specific protease 4 controls metastatic potential through ?-catenin stabilization in brain metastatic lung adenocarcinoma.
Adenocarcinoma of Lung
Ubiquitin-specific protease 8 is a novel prognostic marker in early-stage lung adenocarcinoma.
Adenocarcinoma of Lung
USP22 promotes development of lung adenocarcinoma through ubiquitination and immunosuppression.
Adenocarcinoma of Lung
[Analysis of the correlation between the expression of WFDC2 in B cells of lung adenocarcinoma tissue and the survival rate of patients].
Adenoma
A comparative study of E-cadherin and stromelysin-3 expression in de novo and ex adenoma carcinoma of the colorectum.
Adenoma
Autocrine induction of invasion and metastasis by tumor-associated trypsin inhibitor in human colon cancer cells.
Adenoma
Changes in cyclic adenosine 3':5'-monophosphate-dependent protein kinases during the progression of urethan-induced mouse lung tumors.
Adenoma
LonP1 Differently Modulates Mitochondrial Function and Bioenergetics of Primary Versus Metastatic Colon Cancer Cells.
Adenoma
Simultaneous fluorescence imaging of protease expression and vascularity during murine colonoscopy for colonic lesion characterization.
Adenoma
The Gene of the Ubiquitin-Specific Protease 8 Is Frequently Mutated in Adenomas Causing Cushing's Disease.
Adenoma
Tumor marker utility and prognostic relevance of cathepsin B, cathepsin L, urokinase-type plasminogen activator, plasminogen activator inhibitor type-1, CEA and CA 19-9 in colorectal cancer.
Adenoma
Tumor-promoter-enhanced destruction of noninvasive human benign colon tumor cells by cocultivated carcinoma cells.
Adenoma
Urinary protease inhibitor Serpin B3 is higher in women and is further increased in female patients affected by aldosterone producing adenoma.
Adenomatous Polyposis Coli
Therapeutic Targeting of Nuclear Export Inhibition in Lung Cancer.
Adenomatous Polyposis Coli
Three Female Familial Cases of Solid Pseudopapillary Tumors With a Protease Serine 1 Gene Mutation.
Adrenal Insufficiency
High frequency of hypothalamic-pituitary-adrenal axis dysfunction after local corticosteroid injection in HIV-infected patients on protease inhibitor therapy.
Adrenoleukodystrophy
Protease inhibitors suppress the degradation of mutant adrenoleukodystrophy proteins but do not correct impairment of very long chain fatty acid metabolism in adrenoleukodystrophy fibroblasts.
African Swine Fever
African swine fever virus protease, a new viral member of the SUMO-1-specific protease family.
African Swine Fever
Crystal structure of the African swine fever virus pS273R protease and implications for inhibitor design.
African Swine Fever
Inhibition of African swine fever virus protease by myricetin and myricitrin.
African Swine Fever
Membrane association facilitates the correct processing of pp220 during production of the major matrix proteins of African swine fever virus.
African Swine Fever
Polyprotein processing protease of African swine fever virus: purification and biochemical characterization.
Aggressive Periodontitis
Concentrations of serum protease inhibitors and immunoglobulins in juvenile periodontitis.
Aggressive Periodontitis
Dermatologic, periodontal, and skeletal manifestations of Haim-Munk syndrome in two siblings.
Aggressive Periodontitis
Periodontal pathogens affect the level of protease inhibitors in gingival crevicular fluid.
Agranulocytosis
Continuous regional arterial infusion effective for children with acute necrotizing pancreatitis even under neutropenia.
AIDS Dementia Complex
Cocaine potentiates cathepsin B secretion and neuronal apoptosis from HIV-infected macrophages.
AIDS Dementia Complex
Regression of HIV encephalopathy and basal ganglia signal intensity abnormality at MR imaging in patients with AIDS after the initiation of protease inhibitor therapy.
AIDS Dementia Complex
The impact of pharmacologic and genetic knockout of P-glycoprotein on nelfinavir levels in the brain and other tissues in mice.
Airway Obstruction
Ageing and smoking contribute to plasma surfactant proteins and protease imbalance with correlations to airway obstruction.
Airway Obstruction
Interrelationships between neutrophil elastase, serum alpha, -antitrypsin, lung function and chest radiography in patients with chronic airflow obstruction.
Albuminuria
Antiserum against tumor necrosis factor-alpha and a protease inhibitor reduce immune glomerular injury.
Albuminuria
Impact of protease inhibitors on the evolution of urinary markers: Subanalyses from an observational cross-sectional study.
Albuminuria
Proteases and protease inhibitors of urinary extracellular vesicles in diabetic nephropathy.
Albuminuria
Urinary albumin excretion within the normal range is an independent risk for near-term development of kidney disease in HIV-infected patients.
Alopecia
Dermatologic adverse effects of antiretroviral therapy: recognition and management.
Alopecia
Malt1 Protease Is Critical in Maintaining Function of Regulatory T Cells and May Be a Therapeutic Target for Antitumor Immunity.
Alopecia
The mRNA for protease nexin-1 is expressed in human dermal papilla cells and its level is affected by androgen.
alpha 1-Antitrypsin Deficiency
Alpha 1-antitrypsin deficiency in a child with X-linked lymphoproliferative disease.
alpha 1-Antitrypsin Deficiency
Analysis of two common alpha 1-antitrypsin deficiency alleles (PI*Z and PI*S) in subjects with periodontitis.
alpha 1-Antitrypsin Deficiency
Inhaled recombinant alpha 1-antitrypsin ameliorates cigarette smoke-induced emphysema in the mouse.
alpha 1-Antitrypsin Deficiency
PCR-Based Screening for the Most Prevalent Alpha 1 Antitrypsin Deficiency Mutations (PI S, Z, and Mmalton) in COPD Patients from Eastern Tunisia.
alpha 1-Antitrypsin Deficiency
Protease-Specific Biomarkers to Analyse Protease Inhibitors for Emphysema Associated with Alpha 1-Antitrypsin Deficiency. An Overview of Current Approaches.
alpha 1-Antitrypsin Deficiency
Pulmonary function in heterozygotes for alpha,-antitrypsin deficiency: a case-control study.
alpha 1-Antitrypsin Deficiency
The protease inhibitor PI*S allele and COPD: a meta-analysis.
alpha 1-Antitrypsin Deficiency
[Early childhood oligoarthritis (antinuclear antibody positive) in alpha 1-antitrypsin deficiency of the PiIZ type]
alpha 1-Antitrypsin Deficiency
[Mucous membrane specific protease inhibitors in bronchial mucus in severe chronic obstructive bronchitis and in alpha 1-antitrypsin deficiency syndrome]
Alveolitis, Extrinsic Allergic
Intracellular protease changes in acute experimental hypersensitivity pneumonitis.
Alzheimer Disease
4-substituted cyclohexyl sulfones as potent, orally active gamma-secretase inhibitors.
Alzheimer Disease
?-Secretase Activity Is Required for Regulated Intramembrane Proteolysis of Tumor Necrosis Factor (TNF) Receptor 1 and TNF-mediated Pro-apoptotic Signaling.
Alzheimer Disease
?-Secretase in microglia - Implications for neurodegeneration and neuroinflammation.
Alzheimer Disease
?-secretase inhibitory activity of phenolic acid conjugated chitooligosaccharides.
Alzheimer Disease
?-Secretase-cleaved Tau stimulates A? production via upregulating STAT1-BACE1 signaling in Alzheimer's disease.
Alzheimer Disease
?-Secretase-Regulated Mechanisms Similar to Notch Signaling May Play a Role in Signaling Events, Including APP Signaling, Which Leads to Alzheimer's Disease.
Alzheimer Disease
A calcium-activated protease from Alzheimer's disease brain cleaves at the N-terminus of the amyloid beta-protein.
Alzheimer Disease
A Canine Model to Evaluate Efficacy and Safety of ?-Secretase Inhibitors and Modulators.
Alzheimer Disease
A common genetic system for functional studies of pitrilysin and related M16A proteases.
Alzheimer Disease
A new promoter polymorphism in the alpha-1-antichymotrypsin gene is a disease modifier of Alzheimer's disease.
Alzheimer Disease
A noncompetitive BACE1 inhibitor TAK-070 ameliorates Abeta pathology and behavioral deficits in a mouse model of Alzheimer's disease.
Alzheimer Disease
A Novel 2-DE-Based Proteomic Analysis to Identify Multiple Substrates for Specific Protease in Neuronal Cells.
Alzheimer Disease
A protease activity associated with acetylcholinesterase releases the membrane-bound form of the amyloid protein precursor of Alzheimer's disease.
Alzheimer Disease
A protease is recovered with a dimeric form of acetylcholinesterase in fetal bovine serum.
Alzheimer Disease
A role for apoE in regulating the levels of alpha-1-antichymotrypsin in the aging mouse brain and in Alzheimer's disease.
Alzheimer Disease
A serine protease in Alzheimer's disease cells cleaves a 16K-peptide with flanking residues upstream to beta-amyloid-N-terminus as natural substrate.
Alzheimer Disease
Activation and enzymatic characterization of recombinant human kallikrein 8.
Alzheimer Disease
Activation of ?-Secretase Trimming Activity by Topological Changes of Transmembrane Domain 1 of Presenilin 1.
Alzheimer Disease
Activity-dependent isolation of the presenilin- gamma -secretase complex reveals nicastrin and a gamma substrate.
Alzheimer Disease
Addition of protease inhibitors to culture medium of neuroblastoma cells induces both neurite outgrowth and phosphorylation of microtubule-associated protein MAP-1B.
Alzheimer Disease
Age-related increase in a cathepsin D like protease that degrades brain microtubule-associated proteins.
Alzheimer Disease
Aging and Alzheimer's disease: protease inhibitors in cerebrospinal fluid.
Alzheimer Disease
Alpha 1-antichymotrypsin binding to Alzheimer A beta peptides is sequence specific and induces fibril disaggregation in vitro.
Alzheimer Disease
Alpha 1-antichymotrypsin is associated solely with amyloid deposits containing the beta-protein. Amyloid and cell localization of alpha 1-antichymotrypsin.
Alzheimer Disease
Alpha 1-antichymotrypsin is present together with the beta-protein in monkey brain amyloid deposits.
Alzheimer Disease
Alzheimer's beta-secretase cleaves a glycosyltransferase as a physiological substrate.
Alzheimer Disease
Alzheimer's therapy targeting the ?-secretase enzyme BACE1: Benefits and potential limitations from the perspective of animal model studies.
Alzheimer Disease
Amylin and its analogs: a friend or foe for the treatment of Alzheimer's disease?
Alzheimer Disease
Amyloid beta protein precursor with Kunitz-type protease inhibitor domains (APPI) in cerebrospinal fluid and APPI mRNAs in cultured skin fibroblasts of patients with Alzheimer's disease.
Alzheimer Disease
Amyloid protein precursor messenger RNAs: differential expression in Alzheimer's disease.
Alzheimer Disease
Amyloid-associated proteins alpha 1-antichymotrypsin and apolipoprotein E promote assembly of Alzheimer beta-protein into filaments.
Alzheimer Disease
An aberrant sugar modification of BACE1 blocks its lysosomal targeting in Alzheimer's disease.
Alzheimer Disease
An exo-cell assay for examining real-time gamma-secretase activity and inhibition.
Alzheimer Disease
APP with Kunitz type protease inhibitor domain (KPI) correlates with neuritic plaque density but not with cortical synaptophysin immunoreactivity in Alzheimer's disease and non-demented aged subjects: a multifactorial analysis.
Alzheimer Disease
Application of a Bioinformatics-Based Approach to Identify Novel Putative in vivo BACE1 Substrates.
Alzheimer Disease
Archaeal proteasomes effectively degrade aggregation-prone proteins and reduce cellular toxicities in mammalian cells.
Alzheimer Disease
Asparagine Endopeptidase (? Secretase), an Enzyme Implicated in Alzheimer's Disease Pathology, Is an Inhibitor of Axon Regeneration in Peripheral Nerves.
Alzheimer Disease
Association of serum AACT levels and AACT signal polymorphism with late-onset Alzheimer's disease in Northern Ireland.
Alzheimer Disease
Astrocytes in Alzheimer's disease gray matter express alpha 1-antichymotrypsin mRNA.
Alzheimer Disease
BACE-1 inhibitory activities of new substituted phenyl-piperazine coupled to various heterocycles: Chromene, coumarin and quinoline.
Alzheimer Disease
Bace1 and Neuregulin-1 cooperate to control formation and maintenance of muscle spindles.
Alzheimer Disease
BACE1 inhibition more effectively suppresses initiation than progression of ?-amyloid pathology.
Alzheimer Disease
BACE1 Inhibitor MK-8931 Alters Formation but Not Stability of Dendritic Spines.
Alzheimer Disease
BACE1 Physiological Functions May Limit Its Use as Therapeutic Target for Alzheimer's Disease.
Alzheimer Disease
BACE1 SUMOylation increases its stability and escalates the protease activity in Alzheimer's disease.
Alzheimer Disease
BACE2 is stored in secretory granules of mouse and rat pancreatic beta cells.
Alzheimer Disease
Biochemical Differentiation of Cholinesterases from Normal and Alzheimer's Disease Cortex.
Alzheimer Disease
Bisecting GlcNAc modification stabilizes BACE1 protein under oxidative stress conditions.
Alzheimer Disease
Brain membrane serine protease activity in human cortex compared with rat: implication for Alzheimer's disease.
Alzheimer Disease
Ca(2+)-dependent 68-kilodalton protease in familial Alzheimer's disease cells cleaves the N-terminus of beta-amyloid.
Alzheimer Disease
Calcicludine, a venom peptide of the Kunitz-type protease inhibitor family, is a potent blocker of high-threshold Ca2+ channels with a high affinity for L-type channels in cerebellar granule neurons.
Alzheimer Disease
Caspase vinyl sulfone small molecule inhibitors prevent axonal degeneration in human neurons and reverse cognitive impairment in Caspase-6-overexpressing mice.
Alzheimer Disease
Caspase-3 cleaved spectrin colocalizes with neurofilament-immunoreactive neurons in Alzheimer's disease.
Alzheimer Disease
Caspase-6 activity predicts lower episodic memory ability in aged individuals.
Alzheimer Disease
Cathepsin D regulates cerebral A?42/40 ratios via differential degradation of A?42 and A?40.
Alzheimer Disease
Cathepsin D: screening for new polymorphisms using single-strand conformation polymorphism analysis.
Alzheimer Disease
Cellular localization and enzymatic activity of cathepsin B after spinal cord injury in the rat.
Alzheimer Disease
Cerebrospinal fluid of patients with senile dementia of Alzheimer's type shows an increased inhibition of alpha-chymotrypsin.
Alzheimer Disease
Characterization of a novel positive transcription regulatory element that differentially regulates the alpha-2-macroglobulin gene in replicative senescence.
Alzheimer Disease
Characterization of the serpin, alpha 1-antichymotrypsin, in normal human cerebrospinal fluid.
Alzheimer Disease
Click Chemistry-mediated Biotinylation Reveals a Function for the Protease BACE1 in Modulating the Neuronal Surface Glycoproteome.
Alzheimer Disease
Clipsin, a chymotrypsin-like protease in rat brain which is irreversibly inhibited by alpha-1-antichymotrypsin.
Alzheimer Disease
Comparison of cathepsin protease activities in brain tissue from normal cases and cases with Alzheimer's disease, Lewy body dementia, Parkinson's disease and Huntington's disease.
Alzheimer Disease
Complex translational regulation of BACE1 involves upstream AUGs and stimulatory elements within the 5' untranslated region.
Alzheimer Disease
Conformational transition in the substrate binding domain of ?-secretase exploited by NMA and its implication in inhibitor recognition: BACE1-myricetin a case study.
Alzheimer Disease
Consecutive Analysis of BACE1 Function on Developing and Developed Neuronal Cells.
Alzheimer Disease
Contribution of a metal-peroxide adduct to neurodegeneration is due to its oxidative protease activity.
Alzheimer Disease
Cooperative Roles of Hydrophilic Loop 1 and the C-Terminus of Presenilin 1 in the Substrate-Gating Mechanism of ?-Secretase.
Alzheimer Disease
Correction for Bao et al., BACE1 SUMOylation increases its stability and escalates the protease activity in Alzheimer's disease.
Alzheimer Disease
Cryoelectron microscopy structure of purified gamma-secretase at 12 A resolution.
Alzheimer Disease
Curcumin inhibits BACE1 expression through the interaction between ER? and NF?B signaling pathway in SH-SY5Y cells.
Alzheimer Disease
Decrease in catalytic capacity of ?-secretase can facilitate pathogenesis in sporadic and Familial Alzheimer's disease.
Alzheimer Disease
Decreased cerebrospinal fluid levels of neurosin (KLK6), an aging-related protease, as a possible new risk factor for Alzheimer's disease.
Alzheimer Disease
Deletion of the fission yeast homologue of human insulinase reveals a TORC1-dependent pathway mediating resistance to proteotoxic stress.
Alzheimer Disease
Demonstration by FRET of BACE interaction with the amyloid precursor protein at the cell surface and in early endosomes.
Alzheimer Disease
Demonstration of an active component of inter-alpha-trypsin inhibitor in the brains of Alzheimer type dementia.
Alzheimer Disease
Demonstration of puromycin-sensitive alanyl aminopeptidase in Alzheimer disease brain.
Alzheimer Disease
Detection of interleukin-6 and alpha 2-macroglobulin immunoreactivity in cortex and hippocampus of Alzheimer's disease patients.
Alzheimer Disease
Development and Mechanism of ?-Secretase Modulators for Alzheimer's Disease.
Alzheimer Disease
Developmental expression of alpha 1-antichymotrypsin in brain may be related to astrogliosis.
Alzheimer Disease
Differential deregulation of NGF and BDNF neurotrophins in a transgenic rat model of Alzheimer's disease.
Alzheimer Disease
Differential involvement of caspase-6 in amyloid-?-induced fragmentation of lamin A and B.
Alzheimer Disease
Distribution pattern and functional state of alpha 1-antichymotrypsin in plaques and vascular amyloid in Alzheimer's disease. A immunohistochemical study with monoclonal antibodies against native and inactivated alpha 1-antichymotrypsin.
Alzheimer Disease
Dual Signal Amplification Electrochemical Biosensor for Monitoring the Activity and Inhibition of the Alzheimer's Related Protease ?-Secretase.
Alzheimer Disease
Ectodomain shedding of the amyloid precursor protein: cellular control mechanisms and novel modifiers.
Alzheimer Disease
Effect of neurotoxic metal ions in vitro on proteolytic enzyme activities in human cerebral cortex.
Alzheimer Disease
Effects of HNE-modification induced by Abeta on neprilysin expression and activity in SH-SY5Y cells.
Alzheimer Disease
Electron microscopic structure of purified, active gamma-secretase reveals an aqueous intramembrane chamber and two pores.
Alzheimer Disease
Encompassing receptor flexibility in virtual screening using ensemble docking-based hybrid QSAR: discovery of novel phytochemicals for BACE1 inhibition.
Alzheimer Disease
Enhanced plasmin inhibition by a reactive center lysine mutant of the Kunitz-type protease inhibitor domain of the amyloid beta-protein precursor.
Alzheimer Disease
Enzyme specificity of proteinase inhibitor region in amyloid precursor protein of Alzheimer's disease: different properties compared with protease nexin I.
Alzheimer Disease
ERK1/2 is an endogenous negative regulator of the gamma-secretase activity.
Alzheimer Disease
Excessive urokinase-type plasminogen activator activity in the euglobulin fraction of patients with Alzheimer-type dementia.
Alzheimer Disease
Expression analysis of beta-secretase 1 (BACE1) and its naturally occurring antisense (BACE1-AS) in blood of epileptic patients.
Alzheimer Disease
Expression and cellular localization of amyloid beta-protein precursor transcripts in normal human brain and in Alzheimer's disease.
Alzheimer Disease
Expression of the Alzheimer amyloid-promoting factor antichymotrypsin is induced in human astrocytes by IL-1.
Alzheimer Disease
Femtomolar Detection of Thrombin in Serum and Cerebrospinal Fluid via Direct Electrocatalysis of Oxygen Reduction by the Covalent G4-Hemin-Aptamer Complex.
Alzheimer Disease
Fibrillar amyloid beta-protein inhibits the activity of high molecular weight brain protease and trypsin.
Alzheimer Disease
Functions of the Alzheimer's Disease Protease BACE1 at the Synapse in the Central Nervous System.
Alzheimer Disease
Gamma-secretase subunit composition and distribution in the presenilin wild-type and mutant mouse brain.
Alzheimer Disease
Gamma-secretase: a catalyst of Alzheimer disease and signal transduction.
Alzheimer Disease
gamma-Secretase: characterization and implication for Alzheimer disease therapy.
Alzheimer Disease
Genetic analysis of the alpha2-macroglobulin gene in early- and late-onset Parkinson's disease.
Alzheimer Disease
Genetic knockdown of Klk8 has sex-specific multi-targeted therapeutic effects on Alzheimer's pathology in mice.
Alzheimer Disease
Got RIP? Presenilin-dependent intramembrane proteolysis in growth factor receptor signaling.
Alzheimer Disease
High expression on Kunitz-type protease inhibitor-containing substances in the cerebral vessels of patients with Down syndrome.
Alzheimer Disease
Human brain proteins showing neuron-specific interactions with ?-secretase.
Alzheimer Disease
Hybrid approach to sieve out natural compounds against dual targets in Alzheimer's Disease.
Alzheimer Disease
Identification of a chymotrypsin-like mast cell protease in rat brain capable of generating the N-terminus of the Alzheimer amyloid beta-protein.
Alzheimer Disease
Identification of a metalloprotease from Alzheimer's disease brain able to degrade the beta-amyloid precursor protein and generate amyloidogenic fragments.
Alzheimer Disease
Identification of different ? amyloid cDNAs cloned from the brain of a patient with sporadic alzheimer's disease.
Alzheimer Disease
Identification of human presequence protease (hPreP) agonists for the treatment of Alzheimer's disease.
Alzheimer Disease
Identification of novel ?-secretase associated proteins in detergent resistant membranes from brain.
Alzheimer Disease
Identification of Novel BACE1 Inhibitors by Combination of Pharmacophore Modeling, Structure-Based Design and In Vitro Assay.
Alzheimer Disease
Immunochemical identification of the serine protease inhibitor alpha 1-antichymotrypsin in the brain amyloid deposits of Alzheimer's disease.
Alzheimer Disease
In-silico analysis and QSAR studies of tacrine hybrids with ubiquitin ligase on Alzheimer's disease.
Alzheimer Disease
Increased cross-linking micelle retention in the brain of Alzheimer's disease mice by elevated asparagine endopeptidase protease responsive aggregation.
Alzheimer Disease
Increased neuronal endocytosis and protease delivery to early endosomes in sporadic Alzheimer's disease: neuropathologic evidence for a mechanism of increased beta-amyloidogenesis.
Alzheimer Disease
Increased tissue factor pathway inhibitor and homocysteine in Alzheimer's disease.
Alzheimer Disease
Inhibition of BACE2 counteracts hIAPP-induced insulin secretory defects in pancreatic ?-cells.
Alzheimer Disease
Insulin degrading enzyme (IDE) genetic variants and risk of Alzheimer's disease: evidence of effect modification by apolipoprotein E (APOE).
Alzheimer Disease
Interleukin-1 beta and tumor necrosis factor-alpha induce expression of alpha 1-antichymotrypsin in human astrocytoma cells by activation of nuclear factor-kappa B.
Alzheimer Disease
Internalization of exogenously added memapsin 2 (beta-secretase) ectodomain by cells is mediated by amyloid precursor protein.
Alzheimer Disease
Kallikrein-related peptidase 6 in Alzheimer's disease and vascular dementia.
Alzheimer Disease
Kunitz protease inhibitor-containing amyloid beta protein precursor immunoreactivity in Alzheimer's disease.
Alzheimer Disease
Label-free Quantitative Proteomics of Mouse Cerebrospinal Fluid Detects ?-Site APP Cleaving Enzyme (BACE1) Protease Substrates In Vivo.
Alzheimer Disease
Lack of association between angiotensin-converting enzyme and dementia of the Alzheimer's type in an elderly Arab population in Wadi Ara, Israel.
Alzheimer Disease
Localization of HtrA2/Omi immunoreactivity in brains affected by Alzheimer's disease.
Alzheimer Disease
Loss of spr-5 bypasses the requirement for the C.elegans presenilin sel-12 by derepressing hop-1.
Alzheimer Disease
LRP1 Downregulates the Alzheimer's ?-Secretase BACE1 by Modulating Its Intraneuronal Trafficking(1,2,3).
Alzheimer Disease
Lysosomal protease inhibitors induce meganeurites and tangle-like structures in entorhinohippocampal regions vulnerable to Alzheimer's disease.
Alzheimer Disease
Membrane dynamics of ?-secretase with the anterior pharynx-defective 1B subunit.
Alzheimer Disease
Mitochondria and Alzheimer's disease: amyloid-beta peptide uptake and degradation by the presequence protease, hPreP.
Alzheimer Disease
Modulation of ?-secretase activity by multiple enzyme-substrate interactions: implications in pathogenesis of Alzheimer's disease.
Alzheimer Disease
Molecular characterization and temporal expression profiling of presenilins in the developing porcine brain.
Alzheimer Disease
Molecular characterization of the minimal protease resistant tau unit of the Alzheimer's disease paired helical filament.
Alzheimer Disease
Molecular cloning of human cDNA with a sequence highly similar to that of the dihydrofolate reductase gene in brain libraries derived from Alzheimer's disease patients.
Alzheimer Disease
Molecular docking and 3D-QSAR studies on the binding mechanism of statine-based peptidomimetics with beta-secretase.
Alzheimer Disease
Molecular dynamics of C99-bound ?-secretase reveal two binding modes with distinct compactness, stability, and active-site retention: implications for A? production.
Alzheimer Disease
Molecular evolution of serine protease and its inhibitor with special reference to domain evolution.
Alzheimer Disease
Molecular studies define the primary structure of alpha1-antichymotrypsin (ACT) protease inhibitor in Alzheimer's disease brains. Comparison of act in hippocampus and liver.
Alzheimer Disease
Monoamine oxidase B is elevated in Alzheimer disease neurons, is associated with ?-secretase and regulates neuronal amyloid ?-peptide levels.
Alzheimer Disease
Neprilysin Inhibits Coagulation through Proteolytic Inactivation of Fibrinogen.
Alzheimer Disease
No association between high temperature requirement 1 (HTRA1) gene polymorphisms and Alzheimer's disease.
Alzheimer Disease
Novel precursor of Alzheimer's disease amyloid protein shows protease inhibitory activity.
Alzheimer Disease
One round of SELEX for the generation of DNA aptamers directed against KLK6.
Alzheimer Disease
Parkinson's Disease: A Systemic Inflammatory Disease Accompanied by Bacterial Inflammagens.
Alzheimer Disease
Partial rescue of the p35-/- brain phenotype by low expression of a neuronal-specific enolase p25 transgene.
Alzheimer Disease
Pathological activity of familial Alzheimer's disease-associated mutant presenilin can be executed by six different gamma-secretase complexes.
Alzheimer Disease
Pharmacological Inhibition of BACE1 Impairs Synaptic Plasticity and Cognitive Functions.
Alzheimer Disease
Plasma and CSF serpins in Alzheimer disease and dementia with Lewy bodies.
Alzheimer Disease
Polymorphic SERPINA3-R124C reduces pathogenesis of its wild type by shortening the lifetime of oligomeric A?.
Alzheimer Disease
Post-treatment with the GLP-1 analogue liraglutide alleviate chronic inflammation and mitochondrial stress induced by Status epilepticus.
Alzheimer Disease
PPARgamma transcriptionally regulates the expression of insulin-degrading enzyme in primary neurons.
Alzheimer Disease
Predicted three-dimensional structure of the protease inhibitor domain of the Alzheimer's disease beta-amyloid precursor.
Alzheimer Disease
Presenilin-1 mutations of leucine 166 equally affect the generation of the Notch and APP intracellular domains independent of their effect on Abeta 42 production.
Alzheimer Disease
Probing Mechanisms and Therapeutic Potential of ?-Secretase in Alzheimer's Disease.
Alzheimer Disease
Processing of cdk5 activator p35 to its truncated form (p25) by calpain in acutely injured neuronal cells.
Alzheimer Disease
Prolonged In Vivo Retention of a Cathepsin D Targeted Optical Contrast Agent in a Mouse Model of Alzheimer's Disease.
Alzheimer Disease
Prostaglandin E2 induced polymerization of human alpha-1-antichymotrypsin and suppressed its protease inhibitory activity: implications for Alzheimer's disease.
Alzheimer Disease
Protease inhibition causes some manifestations of aging and Alzheimer's disease in rodent and primate brain.
Alzheimer Disease
Protease inhibitor domain encoded by an amyloid protein precursor mRNA associated with Alzheimer's disease.
Alzheimer Disease
Protease inhibitors and indolamines selectively inhibit cholinesterases in the histopathologic structures of Alzheimer's disease.
Alzheimer Disease
Protease inhibitors and indoleamines selectively inhibit cholinesterases in the histopathologic structures of Alzheimer disease.
Alzheimer Disease
Protease inhibitors as potential disease-modifying therapeutics for Alzheimer's disease.
Alzheimer Disease
Protease nexin-1 protects against Alzheimer's disease by regulating the sonic hedgehog signaling pathway.
Alzheimer Disease
Protease nexin-1, a potent thrombin inhibitor, is reduced around cerebral blood vessels in Alzheimer's disease.
Alzheimer Disease
Protease nexin-1, an antithrombin with neurite outgrowth activity, is reduced in Alzheimer disease.
Alzheimer Disease
Protease nexin-II (amyloid beta-protein precursor): a platelet alpha-granule protein.
Alzheimer Disease
Proteases and Protease Inhibitors in Alzheimer's Disease Pathogenesis. Proceedings of a conference. Bethesda, Maryland, December 16-18, 1991.
Alzheimer Disease
Proteolysis of calcineurin is increased in human hippocampus during mild cognitive impairment and is stimulated by oligomeric Abeta.
Alzheimer Disease
Proton myo-inositol cotransporter is a novel ?-secretase associated protein that regulates A? production without affecting Notch cleavage.
Alzheimer Disease
Purification of a trypsin-type protease from human umbilical vein endothelial cells which is highly sensitive to the Kunitz inhibitor domain peptide of Alzheimer's disease amyloid protein precursor.
Alzheimer Disease
Quantification of APP and APLP2 mRNA in APOE genotyped Alzheimer's disease brains.
Alzheimer Disease
Quantitative changes in the amyloid beta A4 precursor protein in Alzheimer cerebrospinal fluid.
Alzheimer Disease
Raft disorganization leads to reduced plasmin activity in Alzheimer's disease brains.
Alzheimer Disease
Rapid purification of active gamma-secretase, an intramembrane protease implicated in Alzheimer's disease.
Alzheimer Disease
Reduced A? secretion by human neurons under conditions of strongly increased BACE activity.
Alzheimer Disease
Regulation of Alzheimer's disease amyloid-beta formation by casein kinase I.
Alzheimer Disease
Regulation of serine protease activity by aluminum: implications for Alzheimer disease.
Alzheimer Disease
Relative increase in Alzheimer's disease of soluble forms of cerebral Abeta amyloid protein precursor containing the Kunitz protease inhibitory domain.
Alzheimer Disease
Requirement for small side chain residues within the GxGD-motif of presenilin for gamma-secretase substrate cleavage.
Alzheimer Disease
Screening and Characterization Strategies for Nanobodies Targeting Membrane Proteins.
Alzheimer Disease
Secretase inhibitors for Alzheimer's disease: challenges of a promiscuous protease.
Alzheimer Disease
Seizure protein 6 and its homolog seizure 6-like protein are physiological substrates of BACE1 in neurons.
Alzheimer Disease
Seizure protein 6 controls glycosylation and trafficking of kainate receptor subunits GluK2 and GluK3.
Alzheimer Disease
Sequential NMR resonance assignment and structure determination of the Kunitz-type inhibitor domain of the Alzheimer's beta-amyloid precursor protein.
Alzheimer Disease
Serine protease inhibitor antithrombin III and its messenger RNA in the pathogenesis of Alzheimer's disease.
Alzheimer Disease
Serological alpha 1-antichymotrypsin in Down's syndrome and Alzheimer's disease.
Alzheimer Disease
Serum concentration of alpha 1-antichymotrypsin is elevated in patients with senile dementia of the Alzheimer type.
Alzheimer Disease
Single-entity heparan sulfate glycomimetic clusters for therapeutic applications.
Alzheimer Disease
Sprouting and abnormal contacts of nonmedullated axons, and deposition of extracellular material induced by the amyloid precursor protein (APP) and other protease inhibitors.
Alzheimer Disease
Statins induce insulin-degrading enzyme secretion from astrocytes via an autophagy-based unconventional secretory pathway.
Alzheimer Disease
Structural Characterization of the Amyloid Precursor Protein Transmembrane Domain and Its ?-Cleavage Site.
Alzheimer Disease
Structure prediction of protease inhibitor region in amyloid precursor protein of Alzheimer's disease.
Alzheimer Disease
Structure-activity relationship of presenilin in ?-secretase-mediated intramembrane cleavage.
Alzheimer Disease
Synthesis and secretion of active alpha 1-antichymotrypsin by murine primary astrocytes.
Alzheimer Disease
Synthesis of a targeted library of heparan sulfate hexa- to dodecasaccharides as inhibitors of ?-secretase: potential therapeutics for Alzheimer's disease.
Alzheimer Disease
Tau deletion reduces plaque-associated BACE1 accumulation and decelerates plaque formation in a mouse model of Alzheimer's disease.
Alzheimer Disease
Tensor decomposition of stimulated monocyte and macrophage gene expression profiles identifies neurodegenerative disease-specific trans-eQTLs.
Alzheimer Disease
The Alzheimer's plaques, tangles and memory deficits may have a common origin. Part IV: can calpain act as alpha-secretase?
Alzheimer Disease
The amyloid beta-protein precursor of Alzheimer's disease is degraded extracellularly by a Kunitz protease inhibitor domain-sensitive trypsin-like serine protease in cultures of chick sympathetic neurons.
Alzheimer Disease
The antioxidant xanthorrhizol prevents amyloid-?-induced oxidative modification and inactivation of neprilysin.
Alzheimer Disease
The APMAP interactome reveals new modulators of APP processing and beta-amyloid production that are altered in Alzheimer's disease.
Alzheimer Disease
The beta amyloid protein precursor: mRNAs, membrane-associated forms, and soluble derivatives.
Alzheimer Disease
The cathepsin D (224C/T) polymorphism confers an increased risk to develop Alzheimer's disease in men.
Alzheimer Disease
The cathepsin D rs17571 polymorphism: effects on CSF tau concentrations in Alzheimer disease.
Alzheimer Disease
The inhibition of trypsin and alpha-chymotrypsin proteolytic activity by aluminum(III).
Alzheimer Disease
The involvement of proteases, protease inhibitors, and an acute phase response in Alzheimer's disease.
Alzheimer Disease
The kunitz protease inhibitor form of the amyloid precursor protein (KPI/APP) inhibits the proneuropeptide processing enzyme prohormone thiol protease (PTP). Colocalization of KPI/APP and PTP in secretory vesicles.
Alzheimer Disease
The lipidome associated with the ?-secretase complex is required for its integrity and activity.
Alzheimer Disease
The organellar peptidasome, PreP: A journey from Arabidopsis to Alzheimer's disease.
Alzheimer Disease
The potent BACE1 inhibitor LY2886721 elicits robust central A? pharmacodynamic responses in mice, dogs, and humans.
Alzheimer Disease
The predominant form of the amyloid beta-protein precursor in human brain is protease nexin 2.
Alzheimer Disease
The protease inhibitor, alpha 1-antichymotrypsin, is a component of the brain amyloid deposits in normal aging and Alzheimer's disease.
Alzheimer Disease
The regulatory mechanism of the caspase 6 pro-domain revealed by crystal structure and biochemical assays.
Alzheimer Disease
The serine protease HtrA1 cleaves misfolded transforming growth factor ?-induced protein (TGFBIp) and induces amyloid formation.
Alzheimer Disease
Three SNPs in the GSTO1, GSTO2 and PRSS11 genes on chromosome 10 are not associated with age-at-onset of Alzheimer's disease.
Alzheimer Disease
Thrombin receptor activation induces secretion and nonamyloidogenic processing of amyloid beta-protein precursor.
Alzheimer Disease
Tissue Plasminogen Activator Expression Is Restricted to Subsets of Excitatory Pyramidal Glutamatergic Neurons.
Alzheimer Disease
Tissue-specific expression of three types of beta-protein precursor mRNA: enhancement of protease inhibitor-harboring types in Alzheimer's disease brain.
Alzheimer Disease
TRPC6 specifically interacts with APP to inhibit its cleavage by ?-secretase and reduce A? production.
Alzheimer Disease
Ubiquitin Specific Protease 13 Regulates Tau Accumulation and Clearance in Models of Alzheimer's Disease.
Alzheimer Disease
Understanding BACE1: essential protease for amyloid-beta production in Alzheimer's disease.
Alzheimer Disease
Versatile Functionalization of Poly(methacrylic acid) Brushes with Series of Proteolytically Cleavable Peptides for Highly Sensitive Protease Assay.
Alzheimer Disease
Visualizing protein-ligand binding with chemical energy-wise decomposition (CHEWD): application to ligand binding in the kallikrein-8 S1 Site.
Alzheimer Disease
[The significance of measurement of contents of serum serine protease inhibitors in senile dementia of the Alzheimer type]
Alzheimer Disease
[Therapeutic strategy by manipulating some protease activities for Alzheimer's disease]
Alzheimer Disease
[Understanding of molecular pathogenesis of Alzheimer's disease: implications for drug development]
Amyloidosis
Alpha 2-macroglobulin protects some of the protein constituents of dialysis-associated amyloidosis from protease degradation.
Amyloidosis
Biochemical nature and cellular origin of amyloid enhancing factor (AEF) as determined by anti-AEF antibody.
Amyloidosis
Cathepsin protease activity modulates amyloid load in extracerebral amyloidosis.
Amyloidosis
Identification of fibronectin type I domains as amyloid-binding modules on tissue-type plasminogen activator and three homologs.
Amyloidosis
Molecular imaging of amyloidosis: will the heart be the next target after the brain?
Amyloidosis
Serine protease inhibitor antithrombin III and its messenger RNA in the pathogenesis of Alzheimer's disease.
Amyotrophic Lateral Sclerosis
Abnormal expression of a serine protease in human dystrophic muscle.
Amyotrophic Lateral Sclerosis
Archaeal proteasomes effectively degrade aggregation-prone proteins and reduce cellular toxicities in mammalian cells.
Amyotrophic Lateral Sclerosis
Brain Protease Activated Receptor 1 Pathway: A Therapeutic Target in the Superoxide Dismutase 1 (SOD1) Mouse Model of Amyotrophic Lateral Sclerosis.
Amyotrophic Lateral Sclerosis
Cellular localization and enzymatic activity of cathepsin B after spinal cord injury in the rat.
Amyotrophic Lateral Sclerosis
Contribution of a metal-peroxide adduct to neurodegeneration is due to its oxidative protease activity.
Amyotrophic Lateral Sclerosis
Cytoplasmic, lysosomal and matrix protease activities in spinal cord tissue from amyotrophic lateral sclerosis (ALS) and control patients.
Amyotrophic Lateral Sclerosis
HtrA2/Omi-immunoreactive intraneuronal inclusions in the anterior horn of patients with sporadic and SOD1 mutant amyotrophic lateral sclerosis.
Amyotrophic Lateral Sclerosis
Occurrence of reduced alpha 2-macroglobulin and lowered protease inhibiting capacity in plasma of amyotrophic lateral sclerosis patients.
Amyotrophic Lateral Sclerosis
Related Endogenous Retrovirus-K Elements Harbor Distinct Protease Active Site Motifs.
Amyotrophic Lateral Sclerosis
Studies of protease inhibitors in the sera of patients with amyotrophic lateral sclerosis.
Anaphylaxis
Anaphylactoid reaction induced by a protease inhibitor, nafamostat mesilate, following nine administrations in a hemodialysis patient.
Anaphylaxis
Basal secretion and anaphylactic release of rat mast cell protease-II (RMCP-II) from ex vivo perfused rat jejunum: translocation of RMCP-II into the gut lumen and its relation to mucosal histology.
Anaphylaxis
IgE Sensitization to the Nonspecific Lipid-Transfer Protein Ara h 9 and Peanut-Associated Bronchospasm.
Anaphylaxis
Inhibition of rat endotoxin-induced lethality by BN 52021 and BN 52063, compounds with PAF-acether antagonistic effect and protease-inhibitory activity.
Anaphylaxis
Mast cell protease release and mucosal ultrastructure during intestinal anaphylaxis in the rat.
Anaphylaxis
Mechanism of anaphylaxis in the rabbit; further evidence against plasma protease mechanism.
Anaphylaxis
Plasma contact system activation drives anaphylaxis in severe mast cell-mediated allergic reactions.
Anaphylaxis
Plasma protease inhibitor and anaphylatoxin inactivator levels in chronic urticaria/angioedema and in patients experiencing anaphylactoid reactions to radiographic contrast media.
Anaphylaxis
Studies on tissue protease. V. Protease activity of tissues under anaphylactic shock state.
Anaphylaxis
[Correction with zaditen of impaired activity of pancreatic digestive enzymes in sensitization and anaphylactic shock]
Ancylostomiasis
Isolation and characterization of a proteolytic enzyme from the adult hookworm Ancylostoma caninum.
Androgen-Insensitivity Syndrome
Induction of androgen-dependent protease and serous-like granules by tri-iodothyronine in the submandibular gland of mice with testicular feminization.
Anemia
A mutation in the TMPRSS6 gene, encoding a transmembrane serine protease that suppresses hepcidin production, in familial iron deficiency anemia refractory to oral iron.
Anemia
A novel splice site mutation c.2278 (-1) G>C in the TMPRSS6 gene causes deletion of the substrate binding site of the serine protease resulting in refractory iron deficiency anaemia.
Anemia
Administration of recombinant erythropoietin alone does not improve the phenotype in iron refractory iron deficiency anemia patients.
Anemia
Anemia during treatment with peginterferon Alfa-2b/ribavirin and boceprevir: Analysis from the serine protease inhibitor therapy 2 (SPRINT-2) trial.
Anemia
Anemia in people on second line antiretroviral treatment in Lilongwe, Malawi: a cross-sectional study.
Anemia
Antigenic reactivity of the major glycoprotein of equine infectious anemia virus, a retrovirus.
Anemia
Antiretroviral drug class and anaemia risk in the current treatment era among people living with HIV in the USA: a clinical cohort study.
Anemia
Antiviral effects of peginterferon alpha-2b and ribavirin following 24-week monotherapy of telaprevir in Japanese hepatitis C patients.
Anemia
Combination antiretroviral therapy including a protease inhibitor eliminated the transfusion requirements of HIV-infected individuals with anemia of chronic disease.
Anemia
Common Variants in the TMPRSS6 Gene Alter Hepcidin but not Plasma Iron in Response to Oral Iron in Healthy Gambian Adults: A Recall-by-Genotype Study.
Anemia
delta-Aminolevulinic acid synthetase in erythroblasts of patients with pyridoxine-responsive anemia. Hypercatabolism caused by the increased susceptibility to the controlling protease.
Anemia
Dual Mutation Events in the Haemagglutinin-Esterase and Fusion Protein from an Infectious Salmon Anaemia Virus HPR0 Genotype Promote Viral Fusion and Activation by an Ubiquitous Host Protease.
Anemia
Effects of switching to protease inhibitor monotherapy on nucleoside analogue-related adverse events.
Anemia
Expression of functional protease and subviral particles by vaccinia virus containing equine infectious anaemia virus gag and 5' pol genes.
Anemia
Expression of the protease gene of equine infectious anemia virus in Escherichia coli: formation of the mature processed enzyme and specific cleavage of the gag precursor.
Anemia
Genetic analysis of TMPRSS6 gene in Saudi female patients with iron deficiency anemia.
Anemia
Increased plasma glycosidase and protease activity in uraemia: possible role in the aetiology of the anaemia of chronic renal failure.
Anemia
Liver HFE protein content is posttranscriptionally decreased in iron-deficient mice and rats.
Anemia
Management of anemia induced by triple therapy in patients with chronic hepatitis C: Challenges, opportunities and recommendations.
Anemia
Matriptase-2 mutations in iron-refractory iron deficiency anemia patients provide new insights into protease activation mechanisms.
Anemia
New triple therapy for chronic hepatitis C: real life clinical experience in a community setting.
Anemia
Prasugrel and Acquired Thrombotic Thrombocytopenic Purpura Associated with ADAMTS13 Activity Deficiency.
Anemia
Predictors of early treatment discontinuation and severe anemia in a Brazilian cohort of hepatitis C patients treated with first-generation protease inhibitors.
Anemia
Protease inhibitors-based therapy induces acquired spherocytic-like anaemia and ineffective erythropoiesis in chronic hepatitis C virus patients.
Anemia
Regulation of pregnancy-associated plasma protein A2 (PAPPA2) in a human placental trophoblast cell line (BeWo).
Anemia
Risk factors for anaemia in human immunodeficiency virus/hepatitis C virus-coinfected patients treated with interferon plus ribavirin.
Anemia
Role of ITPA and SLC28A2 genes in the prediction of anaemia associated with protease inhibitor plus ribavirin and peginterferon in hepatitis C treatment.
Anemia
The Association of TMPRSS6 Gene Polymorphism and Iron Intake with Iron Status among Under-Two-Year-Old Children in Lombok, Indonesia.
Anemia
Two nonsense mutations in the TMPRSS6 gene in a patient with microcytic anemia and iron deficiency.
Anemia
[Anaemia and neutropenia in a cohort of non-infected children of HIV-positive mothers]
Anemia
[Paediatric case report of an acquired autoimmune thrombotic thrombocytopenic purpura]
Anemia, Dyserythropoietic, Congenital
Defect in glycosylation of erythrocyte membrane proteins in congenital dyserythropoietic anaemia type II (HEMPAS).
Anemia, Dyserythropoietic, Congenital
Red cell membrane protein anomalies in congenital dyserythropoietic anaemia, type II (HEMP AS).
Anemia, Hemolytic
Congenital microangiopathic hemolytic anemia and thrombocytopenia with unusually large von Willebrand factor multimers and von Willebrand factor-cleaving protease.
Anemia, Hemolytic
Goodpasture's syndrome associated with thrombotic thrombocytopenic purpura secondary to an ADAMTS-13 deficit.
Anemia, Hemolytic
Hemolytic uremic syndrome-associated Shiga toxins promote endothelial-cell secretion and impair ADAMTS13 cleavage of unusually large von Willebrand factor multimers.
Anemia, Hemolytic
Rituximab for chronic recurring thrombotic thrombocytopenic purpura: a case report and review of the literature.
Anemia, Hemolytic
von Willebrand factor-cleaving protease (ADAMTS-13) activity determination in the diagnosis of thrombotic microangiopathies: the Swiss experience.
Anemia, Hemolytic
von Willebrand factor-cleaving protease inhibitor in a patient with human immunodeficiency syndrome-associated thrombotic thrombocytopenic purpura.
Anemia, Hemolytic
[Accessory use of protease-inhibiting agents for disease remission in a patient with autoimmune hemolytic anemia associated with B-CLL]
Anemia, Hemolytic, Autoimmune
[Accessory use of protease-inhibiting agents for disease remission in a patient with autoimmune hemolytic anemia associated with B-CLL]
Anemia, Hemolytic, Autoimmune
[Flow cytometry detection of erythrocyte antigens and antibodies. Technical aspects and new clinical applications]
Anemia, Hypochromic
Deciphering the molecular mechanism behind stimulated co-uptake of arsenic and fluoride from soil, associated toxicity, defence and glyoxalase machineries in arsenic-tolerant rice.
Anemia, Hypochromic
Multiple origins of green coloration in frogs mediated by a novel biliverdin-binding serpin.
Anemia, Iron-Deficiency
A mutation in the TMPRSS6 gene, encoding a transmembrane serine protease that suppresses hepcidin production, in familial iron deficiency anemia refractory to oral iron.
Anemia, Iron-Deficiency
A novel splice site mutation c.2278 (-1) G>C in the TMPRSS6 gene causes deletion of the substrate binding site of the serine protease resulting in refractory iron deficiency anaemia.
Anemia, Iron-Deficiency
Administration of recombinant erythropoietin alone does not improve the phenotype in iron refractory iron deficiency anemia patients.
Anemia, Iron-Deficiency
Genetic analysis of TMPRSS6 gene in Saudi female patients with iron deficiency anemia.
Anemia, Iron-Deficiency
Genetic variability of TMPRSS6 and its association with iron deficiency anaemia.
Anemia, Iron-Deficiency
Liver HFE protein content is posttranscriptionally decreased in iron-deficient mice and rats.
Anemia, Iron-Deficiency
Matriptase-2 mutations in iron-refractory iron deficiency anemia patients provide new insights into protease activation mechanisms.
Anemia, Iron-Deficiency
Tmprss6 is a genetic modifier of the Hfe-hemochromatosis phenotype in mice.
Anemia, Iron-Deficiency
Two nonsense mutations in the TMPRSS6 gene in a patient with microcytic anemia and iron deficiency.
Anemia, Sickle Cell
Relationship of Thrombospondin 1 to von Willebrand Factor and ADAMTS-13 in Sickle Cell Disease Patients of Arab Ethnicity.
Anemia, Sideroblastic
Ferritin and sideroblastic anaemias: inhibition of protein synthesis by protease contaminants in commercial preparations of ferritin.
Aneurysm
Alpha 1-antitrypsin deficiency in intracranial aneurysms and cervical artery dissection.
Aneurysm
Association of the 4G/5G polymorphism in the promoter region of plasminogen activator inhibitor-1 with abdominal aortic aneurysms.
Aneurysm
Cigarette Smoke Extract Activates Tartrate-Resistant Acid Phosphatase-Positive Macrophage.
Aneurysm
Difference in matrix-degrading protease expression and activity between thrombus-free and thrombus-covered wall of abdominal aortic aneurysm.
Aneurysm
Enhanced matrix-degrading proteolytic activity within the thin thrombus-covered wall of human abdominal aortic aneurysms.
Aneurysm
Localization of matrix metalloproteinase 2 within the aneurysmal and normal aortic wall.
Aneurysm
Mast cells modulate the pathogenesis of elastase-induced abdominal aortic aneurysms in mice.
Aneurysm
Multimodality imaging reveals a gradual increase in matrix metalloproteinase activity at aneurysmal lesions in live fibulin-4 mice.
Aneurysm
Osteoclastogenic Differentiation of Macrophages in the Development of Abdominal Aortic Aneurysms.
Aneurysm
Smad2-Dependent Protease Nexin-1 Overexpression Differentiates Chronic Aneurysms From Acute Dissections of Human Ascending Aorta.
Aneurysm, Ruptured
Intracranial Aneurysm Biomarker Candidates Identified by a Proteome-Wide Study.
Angina, Unstable
Pregnancy associated plasma protein-A: ultrasensitive immunoassay and determination in coronary heart disease.
Angioedema
AANA journal course. Update for nurse anesthetists--part 4--life in the balance: the role of serpins in disease genesis and prevention.
Angioedemas, Hereditary
A mutation unique in serine protease inhibitors (serpins) identified in a family with type II hereditary angioneurotic edema.
Angioedemas, Hereditary
Defective glycosylation of coagulation factor XII underlies hereditary angioedema type III.
Angioedemas, Hereditary
Generation of plasmin during acute attacks of hereditary angioedema.
Angioedemas, Hereditary
Hereditary angioedema complicated with chronic renal failure: report of sibling cases.
Angioedemas, Hereditary
Patterns of C1-Inhibitor/Plasma Serine Protease Complexes in Healthy Humans and in Hereditary Angioedema Patients.
Angioedemas, Hereditary
Peptide Macrocycle Inhibitor of Coagulation Factor XII with Subnanomolar Affinity and High Target Selectivity.
Angioedemas, Hereditary
Presence of C1-inhibitor polymers in a subset of patients suffering from hereditary angioedema.
Angioedemas, Hereditary
Studies of four Japanese families with hereditary angioneurotic edema: simultaneous activation of plasma protease systems and exogenous triggering stimuli.
Angioedemas, Hereditary
The autoimmune side of hereditary angioedema: insights on the pathogenesis.
Angioedemas, Hereditary
The Levels of the Lectin Pathway Serine Protease MASP-1 and Its Complex Formation with C1 Inhibitor Are Linked to the Severity of Hereditary Angioedema.
Aniridia
Expression of retinoic acid signaling components ADH7 and ALDH1A1 is reduced in aniridia limbal epithelial cells and a siRNA primary cell based aniridia model.
Anisakiasis
Differential Cleaving of Specific Substrates for Cathepsin-Like Activity Shows Cysteine and Serine Protease Activities and a Differential Profile Between Anisakis simplex s.s. and Anisakis pegreffii, Sibling Species Major Etiologic Agents of Anisakiasis.
Ankylosis
Treatment of collagen induced arthritis by proteolytic enzymes: immunomodulatory and disease modifying effects.
Anthrax
Activation of plasminogen activator inhibitor implicates protease InhA in the acute-phase response to Bacillus anthracis infection.
Anthrax
Anthrax lethal factor cleaves mouse nlrp1b in both toxin-sensitive and toxin-resistant macrophages.
Anthrax
Anthrax lethal toxin disrupts the endothelial permeability barrier through blocking p38 signaling.
Anthrax
Anthrax lethal toxin has direct and potent inhibitory effects on B cell proliferation and immunoglobulin production.
Anthrax
Anthrax lethal toxin promotes dephosphorylation of TTP and formation of processing bodies.
Anthrax
Anthrax toxin requires ZDHHC5-mediated palmitoylation of its surface-processing host enzymes.
Anthrax
Chemical screening by mass spectrometry to identify inhibitors of anthrax lethal factor.
Anthrax
Cross-Reactivity of Anthrax and C2 Toxin: Protective Antigen Promotes the Uptake of Botulinum C2I Toxin into Human Endothelial Cells.
Anthrax
Development of a cell-based fluorescence resonance energy transfer reporter for Bacillus anthracis lethal factor protease.
Anthrax
Direct proteolytic cleavage of NLRP1B is necessary and sufficient for inflammasome activation by anthrax lethal factor.
Anthrax
Dissecting the urokinase activation pathway using urokinase-activated anthrax toxin.
Anthrax
Distinct Contribution of the HtrA Protease and PDZ Domains to Its Function in Stress Resilience and Virulence of Bacillus anthracis.
Anthrax
Diverse mechanisms for inflammasome sensing of cytosolic bacteria and bacterial virulence.
Anthrax
Erk1/2 inactivation promotes a rapid redistribution of COP1 and degradation of COP1 substrates.
Anthrax
Fine structure analysis of the amino acid sequence recognized by the eukaryotic cell protease that activates anthrax toxin.
Anthrax
Frontline Science: Anthrax lethal toxin-induced, NLRP1-mediated IL-1? release is a neutrophil and PAD4-dependent event.
Anthrax
Full Sequence Amino Acid Scanning of ?-Defensin RTD-1 Yields a Potent Anthrax Lethal Factor Protease Inhibitor.
Anthrax
Functional degradation: A mechanism of NLRP1 inflammasome activation by diverse pathogen enzymes.
Anthrax
Identification of inhibitors using a cell-based assay for monitoring Golgi-resident protease activity.
Anthrax
Interaction of the 20 kDa and 63 kDa fragments of anthrax protective antigen: kinetics and thermodynamics.
Anthrax
MEK2 is sufficient but not necessary for proliferation and anchorage-independent growth of SK-MEL-28 melanoma cells.
Anthrax
Mixed-type noncompetitive inhibition of anthrax lethal factor protease by aminoglycosides.
Anthrax
Modulation of the Bacillus anthracis secretome by the immune inhibitor A1 protease.
Anthrax
Proteomics reveals that proteins expressed during the early stage of Bacillus anthracis infection are potential targets for the development of vaccines and drugs.
Anthrax
Purification and Biophysical Characterization of the Core Protease Domain of Anthrax Lethal Factor.
Anthrax
Purified Bacillus anthracis lethal toxin complex formed in vitro and during infection exhibits functional and biological activity.
Anthrax
QSAR and molecular docking studies of lethal factor protease inhibitors against Bacillus anthracis.
Anthrax
Selectively guanidinylated derivatives of neamine. Syntheses and inhibition of anthrax lethal factor protease.
Anthrax
Small-Molecule Inhibitors of Lethal Factor Protease Activity Protect against Anthrax Infection.
Anthrax
Substrate recognition of anthrax lethal factor examined by combinatorial and pre-steady-state kinetic approaches.
Anthrax
Targeting the membrane-anchored serine protease testisin with a novel engineered anthrax toxin prodrug to kill tumor cells and reduce tumor burden.
Anthrax
Ultrasensitive detection of protease activity of anthrax and botulinum toxins by a new PCR-based assay.
Anthrax
Xp38gamma/SAPK3 promotes meiotic G(2)/M transition in Xenopus oocytes and activates Cdc25C.
Anti-Glomerular Basement Membrane Disease
Apheresis in cryoglobulinemia complicating hepatitis C and in other renal diseases.
Anti-Glomerular Basement Membrane Disease
Urine proteome scans uncover total urinary protease, prostaglandin D synthase, serum amyloid P, and superoxide dismutase as potential markers of lupus nephritis.
Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis
Proteinase 3 Interferes With C1q-Mediated Clearance of Apoptotic Cells.
Anus Neoplasms
Performance of the marginal structural cox model for estimating individual and joined effects of treatments given in combination.
Anus Neoplasms
The association between protease inhibitors and anal cancer outcomes in veterans living with HIV treated with definitive chemoradiation: a retrospective study.
Aortic Aneurysm
Interleukin-3 is required for thoracic aneurysm and dissection in a mouse model.
Aortic Aneurysm
Involvement of the mural thrombus as a site of protease release and activation in human aortic aneurysms.
Aortic Aneurysm
Molecular imaging of macrophage protease activity in cardiovascular inflammation in vivo.
Aortic Aneurysm
Relationship Between ?1-Antitrypsin Deficiency and Ascending Aortic Distention.
Aortic Aneurysm, Abdominal
Altered aortic protease and antiprotease activity in patients with ruptured abdominal aortic aneurysms.
Aortic Aneurysm, Abdominal
Assessing the targeting and fate of cathepsin k antibody-modified nanoparticles in a rat abdominal aortic aneurysm model.
Aortic Aneurysm, Abdominal
Cathepsin G deficiency reduces periaortic calcium chloride injury-induced abdominal aortic aneurysms in mice.
Aortic Aneurysm, Abdominal
Chemokine (C-C motif) receptor 2 mediates mast cell migration to abdominal aortic aneurysm lesions in mice.
Aortic Aneurysm, Abdominal
Critical role of mast cell chymase in mouse abdominal aortic aneurysm formation.
Aortic Aneurysm, Abdominal
Difference in matrix-degrading protease expression and activity between thrombus-free and thrombus-covered wall of abdominal aortic aneurysm.
Aortic Aneurysm, Abdominal
Involvement of the mural thrombus as a site of protease release and activation in human aortic aneurysms.
Aortic Aneurysm, Abdominal
Protease activity in the multi-layered intra-luminal thrombus of abdominal aortic aneurysms.
Aortic Aneurysm, Abdominal
Reduced protease inhibitory capacity in patients with abdominal aortic aneurysms is reversed with surgical repair.
Aortic Aneurysm, Abdominal
The calcium messenger system and the kinetics of elastase release from human neutrophils in patients with abdominal aortic aneurysms.
Aortic Aneurysm, Abdominal
The role of inflammation in nonspecific abdominal aortic aneurysm disease.
Aortic Aneurysm, Thoracic
[Effective use of camostat mesilate for chronic disseminated intravascular coagulation complicated by thoracoabdominal aortic aneurysm]
Aortic Diseases
A single nucleotide polymorphism in the matrix metalloproteinase 9 gene (-8202A/G) is associated with thoracic aortic aneurysms and thoracic aortic dissection.
Aortic Valve Insufficiency
Association of mannose-binding lectin gene polymorphism but not of mannose-binding serine protease 2 with chronic severe aortic regurgitation of rheumatic etiology.
Aortic Valve Stenosis
Ubiquitin-specific protease as the underlying gene biomarker for aortic stenosis.
Arenaviridae Infections
A Molecular Sensor To Characterize Arenavirus Envelope Glycoprotein Cleavage by Subtilisin Kexin Isozyme 1/Site 1 Protease.
Arenaviridae Infections
Targeting the proteolytic processing of the viral glycoprotein precursor is a promising novel anti-viral strategy against arenaviruses.
Arrhythmias, Cardiac
Monomorphic ventricular tachycardia due to protease inhibitor intoxication by atazanavir.
Arteriosclerosis
Beneficial effect of proteases on allograft arteriosclerosis in a rat aortic model.
Arteriosclerosis
Impact of treatment with protease inhibitors on aortic stiffness in adult patients with human immunodeficiency virus infection.
Arteriosclerosis
Prospective single-arm observational study of human chymase inhibitor Polygonum hydropiper L in subjects with hypertension.
Arteriosclerosis
PROTEOLYTIC ENZYMES : II. THE PHYSIOLOGICAL SIGNIFICANCE OF THE CONTROL OF THEIR ACTIVITY, ESPECIALLY WITH RESPECT TO BACTERIAL GROWTH.
Arteriovenous Fistula
Matrix-Metalloproteinase-2 Predicts Arteriovenous Fistula Failure in Hemodialysis Patients.
Arteriovenous Malformations
Matrix metalloproteinase-9 inhibition attenuates vascular endothelial growth factor-induced intracerebral hemorrhage.
Arteritis
Alternative proteolytic processing of the arterivirus replicase ORF1a polyprotein: evidence that NSP2 acts as a cofactor for the NSP4 serine protease.
Arteritis
Structure and cleavage specificity of the chymotrypsin-like serine protease (3CLSP/nsp4) of Porcine Reproductive and Respiratory Syndrome Virus (PRRSV).
Arthralgia
Arthralgias and cryoglobulinemia during protease inhibitor therapy in a patient infected with human immunodeficiency virus and hepatitis C virus.
Arthralgia
Rheumatological complications associated with the use of indinavir and other protease inhibitors.
Arthritis
6-sulphanilamidoindazole arthritis of rats: relation between acute-phase proteins, degree of arthritis and treatment with soybean trypsin inhibitor.
Arthritis
A correlation between knee cartilage degradation observed by arthroscopy and synovial proteinases activities.
Arthritis
A novel approach to measure the contribution of matrix metalloproteinase in the overall net proteolytic activity present in synovial fluids of patients with arthritis.
Arthritis
Abrogation of antibody-induced arthritis in mice by a self-activating viridin prodrug and association with impaired neutrophil and endothelial cell function.
Arthritis
Adamts5 (aggrecanase-2) is widely expressed in the mouse musculoskeletal system and is induced in specific regions of knee joint explants by inflammatory cytokines.
Arthritis
Amelioration of antigen induced arthritis in rabbits treated with a secreted viral serine proteinase inhibitor.
Arthritis
Association of osteoarthritis with homozygosity for a 5.8 kb Taq I fragment of the alpha 1-antichymotrypsin gene.
Arthritis
Deconstructing the Lectin Pathway in the Pathogenesis of Experimental Inflammatory Arthritis: Essential Role of the Lectin Ficolin B and Mannose-Binding Protein-Associated Serine Protease 2.
Arthritis
Decreased arthritis severity in cathepsin L-deficient mice is attributed to an impaired T helper cell compartment.
Arthritis
Detection of human neutrophil elastase by aptamer affinity capillary electrophoresis coupled with laser-induced fluorescence using specified site fluorescently labeled aptamer.
Arthritis
Development of selective protease inhibitors via engineering of the bait region of human ?2-macroglobulin.
Arthritis
Developmental regulation of synthesis and dimerization of the amyloidogenic protease inhibitor cystatin C in the hematopoietic system.
Arthritis
Discovery and characterization of a novel inhibitor of matrix metalloprotease-13 that reduces cartilage damage in vivo without joint fibroplasia side effects.
Arthritis
Effect of Cervus korean TEMMINCK var. mantchuricus Swinhoe on protease activities, antioxidant and free radical damages in rheumatis arthritis rats.
Arthritis
Essential role of platelet activation via protease activated receptor 4 in tissue factor-initiated inflammation.
Arthritis
Expression of mouse HtrA1 serine protease in normal bone and cartilage and its upregulation in joint cartilage damaged by experimental arthritis.
Arthritis
Fibroblast activation protein-?: a key modulator of the microenvironment in multiple pathologies.
Arthritis
In vivo imaging of protease activity in arthritis: a novel approach for monitoring treatment response.
Arthritis
Increases in mast cells and chymase in fibroproliferative paws of collagen-induced arthritic mice.
Arthritis
Interleukin-1 stimulates the secretion of proteoglycan- and collagen-degrading proteases by rabbit articular chondrocytes.
Arthritis
It is All About Proteases: From Drug Delivery to In Vivo Imaging and Photomedicine.
Arthritis
Liposomal targeting of glucocorticoids to the inflamed synovium inhibits cartilage matrix destruction during murine antigen-induced arthritis.
Arthritis
MALT1 protease activity is required for Fc?R-induced arthritis but not Fc?R-mediated platelet elimination in mice.
Arthritis
Migration inhibition factor-like activity in inflammatory synovial fluids might be due to proteases.
Arthritis
Nafamostat mesylate, a serine protease inhibitor, demonstrates novel antimicrobial properties and effectiveness in Chlamydia-induced arthritis.
Arthritis
Purification and cloning of aggrecanase-1: a member of the ADAMTS family of proteins.
Arthritis
Secretory leukocyte protease inhibitor suppresses the inflammation and joint damage of bacterial cell wall-induced arthritis.
Arthritis
Selective Homogeneous Assay for Circulating Endopeptidase Fibroblast Activation Protein (FAP).
Arthritis
Suppression of streptococcal cell wall-induced arthritis by a potent protease inhibitor, bis(5-amidino-2-benzimidazolyl)methane.
Arthritis
Toxic uveitis caused by pharmacodynamic interactions of Rifabutin and protease inhibitors: a case report.
Arthritis
Treatment of collagen induced arthritis by proteolytic enzymes: immunomodulatory and disease modifying effects.
Arthritis
[Early childhood oligoarthritis (antinuclear antibody positive) in alpha 1-antitrypsin deficiency of the PiIZ type]
Arthritis
[Modification of the adjuvans arthritis by carrageenin, compound 48/80, histamine- and serotonin antagonists, non-steroid antiphlogistics as well as protease inhibitors and their possible relations to inflammation mediators]
Arthritis
[Radioisotope evaluation with Tc 99m of the anti-inflammatory effect of a protease inhibitor in arthritis due to immune complexes and micro-crystals]
Arthritis, Experimental
An antagonist of human protease activated receptor-2 attenuates PAR2 signaling, macrophage activation, mast cell degranulation, and collagen-induced arthritis in rats.
Arthritis, Experimental
An inhibitor of cathepsin K, icariin suppresses cartilage and bone degradation in mice of collagen-induced arthritis.
Arthritis, Experimental
Effects of FUT-175, a novel synthetic protease inhibitor, on the development of adjuvant arthritis in rats and some biological reactions dependent on complement activation.
Arthritis, Experimental
LPS increases the incidence of collagen-induced arthritis in mice through induction of protease HTRA1 expression.
Arthritis, Experimental
Proteins of rat serum V: adjuvant arthritis and its modulation by nonsteroidal anti-inflammatory drugs.
Arthritis, Experimental
[Changes of mucopolysaccharase, protease and collagenolytic activities in rats with adjuvant arthritis and the effects of various anti-inflammatory drugs]
Arthritis, Gouty
NLRP3 inflammasome inhibitor cucurbitacin B suppresses gout arthritis in mice.
Arthritis, Gouty
Rhein, An Anthraquinone Drug, Suppresses the NLRP3 Inflammasome and Macrophage Activation in Urate Crystal-Induced Gouty Inflammation.
Arthritis, Infectious
Impact of staphylococcal protease expression on the outcome of infectious arthritis.
Arthritis, Juvenile
Intraarticular alpha 2-macroglobulin complexes and proteolytic activity in children with juvenile rheumatoid arthritis.
Arthritis, Juvenile
The protease systems and their pathogenic role in juvenile idiopathic arthritis.
Arthritis, Psoriatic
Association of osteoarthritis with homozygosity for a 5.8 kb Taq I fragment of the alpha 1-antichymotrypsin gene.
Arthritis, Psoriatic
Perturbation of protease inhibitors and substrates in inflammatory arthritis.
Arthritis, Reactive
Perturbation of protease inhibitors and substrates in inflammatory arthritis.
Arthritis, Rheumatoid
Association of HLA-DR4, protease inhibitor phenotypes and keratoconjunctivitis sicca with pulmonary abnormalities in rheumatoid arthritis.
Arthritis, Rheumatoid
Association of osteoarthritis with homozygosity for a 5.8 kb Taq I fragment of the alpha 1-antichymotrypsin gene.
Arthritis, Rheumatoid
Characteristics of the protease activity in synovial fluid from patients with rheumatoid arthritis and osteoarthritis.
Arthritis, Rheumatoid
Circulating fibroblast activation protein and dipeptidyl peptidase 4 in rheumatoid arthritis and systemic sclerosis.
Arthritis, Rheumatoid
Demonstration of granzyme A and perforin messenger RNA in the synovium of patients with rheumatoid arthritis.
Arthritis, Rheumatoid
Disease-specific expression patterns of proteases in synovial tissues.
Arthritis, Rheumatoid
Distinct expression of mast cell tryptase and protease activated receptor-2 in synovia of rheumatoid arthritis and osteoarthritis.
Arthritis, Rheumatoid
Effect of a cathepsin K inhibitor on arthritis and bone mineral density in ovariectomized rats with collagen-induced arthritis.
Arthritis, Rheumatoid
Effect of Cervus korean TEMMINCK var. mantchuricus Swinhoe on protease activities, antioxidant and free radical damages in rheumatis arthritis rats.
Arthritis, Rheumatoid
Effects of bee venom on protease activities and free radical damages in synovial fluid from type II collagen-induced rheumatoid arthritis rats.
Arthritis, Rheumatoid
Elevation of activated protein C in synovial joints in rheumatoid arthritis and its correlation with matrix metalloproteinase 2.
Arthritis, Rheumatoid
Expression and activity profiling of selected cysteine cathepsins and matrix metalloproteinases in synovial fluids from patients with rheumatoid arthritis and osteoarthritis.
Arthritis, Rheumatoid
Human gelatinase B, a marker enzyme in rheumatoid arthritis, is inhibited by D-penicillamine: anti-rheumatic activity by protease inhibition.
Arthritis, Rheumatoid
Impaired activity of protease inhibitors towards neutrophil elastase bound to human articular cartilage.
Arthritis, Rheumatoid
Interstitial matrix proteins determine hyaluronan reflection and fluid retention in rabbit joints: effect of protease.
Arthritis, Rheumatoid
LPS increases the incidence of collagen-induced arthritis in mice through induction of protease HTRA1 expression.
Arthritis, Rheumatoid
Lysis of fibrillar collagen by neutrophils in synovial fluid. A role for surface-bound immunoglobulins.
Arthritis, Rheumatoid
Microparticle-induced release of B-lymphocyte regulators by rheumatoid synoviocytes.
Arthritis, Rheumatoid
Nitric oxide-driven hypoxia initiates synovial angiogenesis, hyperplasia and inflammatory lesions in mice.
Arthritis, Rheumatoid
Phosphonic pseudopeptides as human neutrophil elastase inhibitors--a combinatorial approach.
Arthritis, Rheumatoid
Proinflammatory Effects of Ubiquitin-Specific Protease 5 (USP5) in Rheumatoid Arthritis Fibroblast-Like Synoviocytes.
Arthritis, Rheumatoid
Protease inhibitors in rheumatoid synovial fluid. Analyses of electrophoretic homogeneity and protease inhibitory capacity.
Arthritis, Rheumatoid
Proteinase 3 Interferes With C1q-Mediated Clearance of Apoptotic Cells.
Arthritis, Rheumatoid
Regulatory polymorphisms in extracellular matrix protease genes and susceptibility to rheumatoid arthritis: a case-control study.
Arthritis, Rheumatoid
Suppressive effects of Stephania tetrandra on the neutrophil function in patients with rheumatoid arthritis.
Arthritis, Rheumatoid
Synovial tissue protease gene expression and joint erosions in early rheumatoid arthritis.
Arthritis, Rheumatoid
Targeting cathepsin L (CL) by specific ribozymes decreases CL protein synthesis and cartilage destruction in rheumatoid arthritis.
Arthritis, Rheumatoid
The effect of protease inhibitors on the polyclonal B cell activator from the serum of patients with rheumatoid arthritis.
Arthritis, Rheumatoid
The inhibitory effect of IFN-? on protease HTRA1 expression in rheumatoid arthritis.
Arthritis, Rheumatoid
The role of alpha-1-protease inhibitor (A1PI) in the inhibition of protease activity in human knee osteoarthritis.
Arthritis, Rheumatoid
Thrombin-induced expression of RANTES mRNA through protease activated receptor-1 in human synovial fibroblasts.
Arthritis, Rheumatoid
Thrombin-sensitive dual fluorescence imaging and therapeutic agent for detection and treatment of synovial inflammation in murine rheumatoid arthritis.
Arthritis, Rheumatoid
Thrombin-sensitive photodynamic agents: a novel strategy for selective synovectomy in rheumatoid arthritis.
Arthritis, Rheumatoid
Tissue IGFBP-3 proteolysis: contrasting pathophysiology to that in the circulation.
Arthritis, Rheumatoid
[Information value of indices of the protease inhibitor system in diagnosing the early stage of rheumatoid arthritis]
Arthritis, Rheumatoid
[Protease inhibitors in the complex treatment of rheumatoid arthritis]
Arthritis, Rheumatoid
[The possibilities of an individual approach to intra-articular drug administration in rheumatoid arthritis patients]
Arthritis, Rheumatoid
[The status of various indicators of the protease inhibitor system in blood and synovial fluid in rheumatoid arthritis]
Arthus Reaction
[On the increase in the serum protease activity (dipeptidase and tripeptidase) in the Arthus phenomenon.]
Ascorbic Acid Deficiency
Dietary vitamin C deficiency depressed the gill physical barriers and immune barriers referring to Nrf2, apoptosis, MLCK, NF-?B and TOR signaling in grass carp (Ctenopharyngodon idella) under infection of Flavobacterium columnare.
Ascorbic Acid Deficiency
Dietary vitamin C deficiency depresses the growth, head kidney and spleen immunity and structural integrity by regulating NF-?B, TOR, Nrf2, apoptosis and MLCK signaling in young grass carp (Ctenopharyngodon idella).
Aspergillosis
Characterization and identification of proteases secreted by Aspergillus fumigatus using free flow electrophoresis and MS.
Aspergillosis
Evidence for possible involvement of an elastolytic serine protease in aspergillosis.
Aspergillosis
Functional protease profiling for laboratory based diagnosis of invasive aspergillosis.
Aspergillosis
Secretion of a fungal protease represents a complement evasion mechanism in cerebral aspergillosis.
Aspergillosis
Systematic identification of substrates for profiling of secreted proteases from Aspergillus species.
Aspergillosis
The virulence of the opportunistic fungal pathogen Aspergillus fumigatus requires cooperation between the endoplasmic reticulum-associated degradation pathway (ERAD) and the unfolded protein response (UPR).
Aspergillosis, Allergic Bronchopulmonary
Expression and secretion of Aspergillus fumigatus proteases are regulated in response to different protein substrates.
Aspergillosis, Allergic Bronchopulmonary
Recombinant expression and antigenic properties of a 32-kilodalton extracellular alkaline protease, representing a possible virulence factor from Aspergillus fumigatus.
Asthma
A recombinant group 1 house dust mite allergen, rDer f 1, with biological activities similar to those of the native allergen.
Asthma
Accumulation of intraepithelial mast cells with a unique protease phenotype in T(H)2-high asthma.
Asthma
ACE2 expression is elevated in airway epithelial cells from older and male healthy individuals but reduced in asthma.
Asthma
ADAM33 is not essential for growth and development and does not modulate allergic asthma in mice.
Asthma
Allergic reactions, including asthma, to the pineapple protease bromelain following occupational exposure.
Asthma
Alpha-1-antitrypsin and complement component C7 are involved in asthma exacerbation.
Asthma
Alternaria alternata serine proteases induce lung inflammation and airway epithelial cell activation via PAR2.
Asthma
Alternaria-derived serine protease activity drives IL-33 mediated asthma exacerbations(?)
Asthma
Alveolar macrophages play a key role in cockroach-induced allergic inflammation via TNF-? pathway.
Asthma
Analysis of proteolytic enzymes and their natural inhibitors in serum and bronchial lavage fluid in atopic bronchial asthma, chronic bronchitis and pneumonia.
Asthma
Aspergillus fumigatus alkaline protease 1 (Alp1/Asp f13) in the airways correlates with asthma severity.
Asthma
Aspergillus fumigatus Protease Alkaline Protease 1 (Alp1): A New Therapeutic Target for Fungal Asthma.
Asthma
Aspergillus fumigatus proteases, Asp f 5 and Asp f 13, are essential for airway inflammation and remodelling in a murine inhalation model.
Asthma
Association between polymorphisms in serine protease inhibitor, kazal type 5 and asthma phenotypes in a large German population sample.
Asthma
Characterisation of urokinase plasminogen activator receptor variants in human airway and peripheral cells.
Asthma
Circulating immune complexes, complement factors C3, C4, C1-inhibitor, alpha-1-antitrypsin and immunoglobulins in asthmatic patients.
Asthma
Cushing syndrome and severe adrenal suppression caused by fluticasone and protease inhibitor combination in an HIV-infected adolescent.
Asthma
Cyclotheonamide E4 and E5, new potent tryptase inhibitors from an Ircinia species of sponge.
Asthma
Der p 1 suppresses indoleamine 2, 3-dioxygenase in dendritic cells from house dust mite-sensitive patients with asthma.
Asthma
Detection and monitoring of localized matrix metalloproteinase upregulation in a murine model of asthma.
Asthma
Differential bronchial epithelial response regulated by ?Np63: a functional understanding of the epithelial shedding found in asthma.
Asthma
Direct effects of mast cell proteases, tryptase and chymase, on bronchial epithelial integrity proteins and anti-viral responses.
Asthma
Efficacies of immunotherapy with polypeptide vaccine from ProDer f 1 in asthmatic mice.
Asthma
Engineered cystine knot miniproteins as potent inhibitors of human mast cell tryptase beta.
Asthma
Enzymatic activities of allergen extracts from three species of dust mites and cockroaches commonly found in Korean home.
Asthma
Epistasis between serine protease inhibitor Kazal-type 5 (SPINK5) and thymic stromal lymphopoietin (TSLP) genes contributes to childhood asthma.
Asthma
Ex vivo Sputum Analysis Reveals Impairment of Protease-dependent Mucus Degradation by Plasma Proteins in Acute Asthma.
Asthma
Expression and secretion of Aspergillus fumigatus proteases are regulated in response to different protein substrates.
Asthma
German cockroach extract activates protease-activated receptor 2 in human airway epithelial cells.
Asthma
Granulocyte/macrophage-colony-stimulating factor (GM-CSF) regulates lung innate immunity to lipopolysaccharide through Akt/Erk activation of NFkappa B and AP-1 in vivo.
Asthma
Grape Seed Proanthocyanidin Extract Attenuates Allergic Inflammation in Murine Models of Asthma.
Asthma
Heterozygous alpha 1-antichymotrypsin and PiZ alpha 1-antitrypsin deficiency. Prevalence and clinical spectrum in asthmatic children.
Asthma
Inhibitors of chymotrypsin-like proteases inhibit eosinophil peroxidase release from activated human eosinophils.
Asthma
Inhibitory role of eosinophils on cell surface plasmin generation by bronchial epithelial cells: inhibitory effects of transforming growth factor beta.
Asthma
Interaction of secretory leukocyte protease inhibitor with heparin inhibits proteases involved in asthma.
Asthma
Interleukin-28B dampens protease-induced lung inflammation via IL-25 and TSLP inhibition in epithelial cells.
Asthma
Lactoferrin, a potent tryptase inhibitor, abolishes late-phase airway responses in allergic sheep.
Asthma
Metformin reduces airway inflammation and remodeling via activation of AMP-activated protein kinase.
Asthma
Mite and cockroach allergens activate protease-activated receptor 2 and delay epidermal permeability barrier recovery.
Asthma
Molecular mechanism of inhibition of COVID-19 main protease by ?-adrenoceptor agonists and adenosine deaminase inhibitors using in silico methods.
Asthma
Montelukast regulates eosinophil protease activity through a leukotriene-independent mechanism.
Asthma
More Effective DPP4 Inhibitors as Antidiabetics Based on Sitagliptin Applied QSAR and Clinical Methods.
Asthma
Nafamostat mesilate, a potent serine protease inhibitor, inhibits airway eosinophilic inflammation and airway epithelial remodeling in a murine model of allergic asthma.
Asthma
Novel drug targets for asthma and COPD: Lessons learned from in vitro and in vivo models.
Asthma
Observations of development of resistance to detachment of cultured bovine bronchial epithelial cells in response to protease treatment.
Asthma
Protease activated receptor-2 mediated dual oxidase-2 upregulation is involved in enhanced airway reactivity and inflammation in a mouse model of allergic asthma.
Asthma
Protease activated receptor-2 mediated upregulation of IL-17 receptor signaling on airway epithelial cells is responsible for neutrophilic infiltration during acute exposure of house dust mite allergens in mice.
Asthma
Protease inhibitors in respiratory disease: focus on asthma and chronic obstructive pulmonary disease.
Asthma
Protease-activated receptor-2 signaling through ?-arrestin-2 mediates Alternaria alkaline serine protease-induced airway inflammation.
Asthma
Protease-Activated Receptors 2-Antagonist Suppresses Asthma by Inhibiting Reactive Oxygen Species-Thymic Stromal Lymphopoietin Inflammation and Epithelial Tight Junction Degradation.
Asthma
RNA interference decreases PAR-2 expression and function in human airway smooth muscle cells.
Asthma
Secretory leukocyte protease inhibitor plays an important role in the regulation of allergic asthma in mice.
Asthma
Secretory leukocyte protease inhibitor prevents allergen-induced pulmonary responses in animal models of asthma.
Asthma
Serine protease inhibitors nafamostat mesilate and gabexate mesilate attenuate allergen-induced airway inflammation and eosinophilia in a murine model of asthma.
Asthma
SerpinA3n affects ovalbumin (OVA)-induced asthma in neonatal mice via the regulation of collagen deposition and inflammatory response.
Asthma
Serum and bronchial lavage fluid concentrations of IL-8, SLPI, sCD14 and sICAM-1 in patients with COPD and asthma.
Asthma
Subcutaneous Allergic Sensitization to Protease Allergen Is Dependent on Mast Cells but Not IL-33: Distinct Mechanisms between Subcutaneous and Intranasal Routes.
Asthma
Targeting of protease activator receptor-2 (PAR-2) antagonist FSLLRY-NH2 as an asthma adjuvant therapy.
Asthma
The composition of house dust mite is critical for mucosal barrier dysfunction and allergic sensitisation.
Asthma
The Effect of Liposome Encapsulation on the Pharmacokinetics of Recombinant Secretory Leukocyte Protease Inhibitor (rSLPI) Therapy after Local Delivery to a Guinea Pig Asthma Model.
Asthma
The effect of serine protease inhibitors on airway inflammation in a chronic allergen-induced asthma mouse model.
Asthma
The probiotic strain Escherichia coli Nissle 1917 prevents papain-induced respiratory barrier injury and severe allergic inflammation in mice.
Asthma
The role of SCCA1 in asthma related physiological events in the airway epithelium and the effect of promoter variants on asthma and gene function.
Asthma
Tryptase inhibitors block allergen-induced airway and inflammatory responses in allergic sheep.
Asthma
[Effectiveness of the calcium antagonist nifedipine and the protease inhibitor with plasmin inactivating effect para-aminomethylbenzoic acid on stress-induced bronchial asthma]
Asthma
[Etiologic significance of hereditary deficiency of proteinase alpha1-inhibitor in the formation of respiratory diseases]
Asthma
[Inhibition of eosinophil peroxidase release by chymotrypsin type protease inhibitors from activated human eosinophils]
Asthma
[State of protease inhibitor system in patients with occupational bronchial asthma caused by nonferrous metal aerosols]
Asthma, Occupational
Integrated innate mechanisms involved in airway allergic inflammation to the serine protease subtilisin.
Asthma, Occupational
Occupational Asthma to Detergent Protease Associated With a Late-Phase Neutrophilic Cutaneous Response.
Astrocytoma
Epidermal growth factor and pro-inflammatory cytokines regulate the expression of components of plasminogen activation system in U373-MG astrocytoma cells.
Astrocytoma
General protease and collagenase (IV) activity in C6 astrocytoma cells, C6 spheroids and implanted C6 spheroids.
Astrocytoma
Immunohistochemical Evaluation of Hemostatic Changes in Glioblastoma Multiforme and Low-Grade Astrocytoma.
Astrocytoma
Proteolytic activity during the growth of C6 astrocytoma in the murine spheroid implantation model.
Asymptomatic Infections
Severity and persistence of footrot in Merino sheep experimentally infected with a protease thermostable strain of Dichelobacter nodosus at five sites.
Ataxia
Characterization of PTZ-induced seizure susceptibility in a down syndrome mouse model that overexpresses CSTB.
Ataxia
Synaptic defects in ataxia mice result from a mutation in Usp14, encoding a ubiquitin-specific protease.
Ataxia
Transgenic rescue of ataxia mice with neuronal-specific expression of ubiquitin-specific protease 14.
Ataxia Telangiectasia
An ataxia telangiectasia model: inefficient cell differentiation and possible reversal by serine protease inhibitors, tumor necrosis factor inhibitors, dexamethasone, and glutathione enhancers.
Atherosclerosis
In vivo Near Infrared Fluorescence (NIRF) Intravascular Molecular Imaging of Inflammatory Plaque, a Multimodal Approach to Imaging of Atherosclerosis.
Atherosclerosis
A novel association between TGFb1 and ADAMTS4 in coronary artery disease: A new potential mechanism in the progression of atherosclerosis and diabetes.
Atherosclerosis
A peptide analogue of thrombin receptor-activating peptide inhibits thrombin and thrombin-receptor-activating peptide-induced vascular smooth muscle cell proliferation.
Atherosclerosis
Accurate targeting of activated macrophages based on synergistic activation of functional molecules uptake by scavenger receptor and matrix metalloproteinase.
Atherosclerosis
ADAMTS7 Cleavage and Vascular Smooth Muscle Cell Migration Is Affected by a Coronary-Artery-Disease-Associated Variant.
Atherosclerosis
ADAMTS7 locus confers high cross-race risk for development of coronary atheromatous plaque.
Atherosclerosis
Akt1 regulates vascular smooth muscle cell apoptosis through FoxO3a and Apaf1 and protects against arterial remodeling and atherosclerosis.
Atherosclerosis
Analysis of the substrate specificity of Factor VII activating protease (FSAP) and design of specific and sensitive peptide substrates.
Atherosclerosis
Assessment of atherosclerosis using carotid ultrasonography in a cohort of HIV-positive patients treated with protease inhibitors.
Atherosclerosis
Association between Kaposi's sarcoma and atherosclerosis: implications for gammaherpesviruses and vascular disease.
Atherosclerosis
Association of antiretroviral therapy with fibrinogen levels in HIV-infection.
Atherosclerosis
Atorvastatin limits the pro-inflammatory response of rat aortic smooth muscle cells to thrombin.
Atherosclerosis
Bi-cell surface plasmon resonance detection of aptamer mediated thrombin capture in serum.
Atherosclerosis
Caspase-3 Deletion Promotes Necrosis in Atherosclerotic Plaques of ApoE Knockout Mice.
Atherosclerosis
Cathepsin S contributes to macrophage migration via degradation of elastic fibre integrity to facilitate vein graft neointimal hyperplasia.
Atherosclerosis
CD36 overexpression in ritonavir-treated THP-1 cells is reversed by alpha-tocopherol.
Atherosclerosis
Changes in lipid profiles after switching to a protease inhibitor-containing cART--unfavourable effect of fosamprenavir in obese patients.
Atherosclerosis
Characterization of a novel positive transcription regulatory element that differentially regulates the alpha-2-macroglobulin gene in replicative senescence.
Atherosclerosis
Circulating tryptase as a marker for subclinical atherosclerosis in obese subjects.
Atherosclerosis
Circ_USP36/miR-182-5p/KLF5 axis regulates the ox-LDL-induced injury in human umbilical vein smooth muscle cells.
Atherosclerosis
Control of proliferation of human vascular endothelial cells. Characterization of the response of human umbilical vein endothelial cells to fibroblast growth factor, epidermal growth factor, and thrombin.
Atherosclerosis
Coronary artery calcification, atherogenic lipid changes, and increased erythrocyte volume in black injection drug users infected with human immunodeficiency virus-1 treated with protease inhibitors.
Atherosclerosis
Deficiency of cathepsin S reduces atherosclerosis in LDL receptor-deficient mice.
Atherosclerosis
Detection of human neutrophil elastase by aptamer affinity capillary electrophoresis coupled with laser-induced fluorescence using specified site fluorescently labeled aptamer.
Atherosclerosis
Development and validation of novel imaging technologies to assist translational studies in atherosclerosis.
Atherosclerosis
Development of proteinase-activated receptor 1 antagonists as therapeutic agents for thrombosis, restenosis and inflammatory diseases.
Atherosclerosis
Developmental regulation of synthesis and dimerization of the amyloidogenic protease inhibitor cystatin C in the hematopoietic system.
Atherosclerosis
Efavirenz and ritonavir-boosted lopinavir use exhibited elevated markers of atherosclerosis across age groups in people living with HIV in Ethiopia.
Atherosclerosis
Expression of cathepsin K is regulated by shear stress in cultured endothelial cells and is increased in endothelium in human atherosclerosis.
Atherosclerosis
Extracellular matrix metalloproteinase inducer (CD147) is a novel receptor on platelets, activates platelets, and augments nuclear factor kappaB-dependent inflammation in monocytes.
Atherosclerosis
Factors associated with accelerated atherosclerosis in HIV-1-infected persons treated with protease inhibitors.
Atherosclerosis
Granzyme B in atherosclerosis and transplant vascular disease: association with cell death and atherosclerotic disease severity.
Atherosclerosis
Heart and HAART: Two sides of the coin for HIV-associated cardiology issues.
Atherosclerosis
Heparin cofactor II in atherosclerotic lesions from the Pathobiological Determinants of Atherosclerosis in Youth (PDAY) study.
Atherosclerosis
Heparin cofactor II is regulated allosterically and not primarily by template effects. Studies with mutant thrombins and glycosaminoglycans.
Atherosclerosis
High-density lipoproteins protect endothelial cells from tumor necrosis factor-alpha-induced apoptosis.
Atherosclerosis
HIV entry inhibitor TAK-779 attenuates atherogenesis in low-density lipoprotein receptor-deficient mice.
Atherosclerosis
HIV positivity, protease inhibitor exposure, and subclinical atherosclerosis: A systematic review and meta-analysis of observational studies.
Atherosclerosis
HIV protease inhibitors promote atherosclerotic lesion formation independent of dyslipidemia by increasing CD36-dependent cholesteryl ester accumulation in macrophages.
Atherosclerosis
HIV-1 antiretrovirals induce oxidant injury and increase intima-media thickness in an atherogenic mouse model.
Atherosclerosis
Hybrid in vivo FMT-CT imaging of protease activity in atherosclerosis with customized nanosensors.
Atherosclerosis
Impact of diabetes on platelet activation in different manifestations of atherosclerosis.
Atherosclerosis
Intima-Media Thickness in the Carotid and Femoral Arteries for Detection of Arteriosclerosis in Human Immunodeficiency Virus-Positive Individuals.
Atherosclerosis
Involvement of intraplaque hemorrhage in atherothrombosis evolution via neutrophil protease enrichment.
Atherosclerosis
Leukocyte cathepsin C deficiency attenuates atherosclerotic lesion progression by selective tuning of innate and adaptive immune responses.
Atherosclerosis
Loss of protease activity of ADAM15 abolishes protective effects on plaque progression in atherosclerosis.
Atherosclerosis
Low density lipoprotein receptor-related protein (LRP) expression varies among Hep G2 cell lines.
Atherosclerosis
Macrophage-mediated proteolytic remodeling of the extracellular matrix in atherosclerosis results in neoepitopes: a potential new class of biochemical markers.
Atherosclerosis
Macrophages possess both neutral and acidic protease activities toward low density lipoproteins.
Atherosclerosis
Metabolic effects associated to the highly active antiretroviral therapy (HAART) in AIDS patients.
Atherosclerosis
Metalloproteinase-9 contributes to endothelial dysfunction in atherosclerosis via protease activated receptor-1.
Atherosclerosis
Modulation of Cathepsin L Expression in the Coronary Arteries of Atherosclerotic Swine.
Atherosclerosis
Molecular imaging of macrophage protease activity in cardiovascular inflammation in vivo.
Atherosclerosis
Molecular Implications of Natriuretic Peptides in the Protection from Hypertension and Target Organ Damage Development.
Atherosclerosis
Motor and memory testing of long-lived pregnancy-associated plasma protein--a knock-out mice.
Atherosclerosis
Nanoparticles That Sense Thrombin Activity As Synthetic Urinary Biomarkers of Thrombosis.
Atherosclerosis
Neutrophils obtained from obliterative atherosclerotic patients exhibit enhanced resting respiratory burst and increased degranulation in response to various stimuli.
Atherosclerosis
Noncanonical Matrix Metalloprotease 1-Protease-Activated Receptor 1 Signaling Drives Progression of Atherosclerosis.
Atherosclerosis
Pharmacological inhibition of MALT1 protease activity suppresses endothelial activation via enhancing MCPIP1 expression.
Atherosclerosis
Plasma nesfatin-1 and DDP-4 levels in patients with coronary artery disease: Kozani study.
Atherosclerosis
Porphyromonas gingivalis and its lipopolysaccharide differentially regulate the expression of cathepsin B in endothelial cells.
Atherosclerosis
Pregnancy-associated plasma protein-A in atherosclerosis: Molecular marker, mechanistic insight, and therapeutic target.
Atherosclerosis
Premature atherosclerosis in HIV positive patients and cumulated time of exposure to antiretroviral therapy (SHIVA study).
Atherosclerosis
Premature atherosclerosis in HIV-infected individuals--focus on protease inhibitor therapy.
Atherosclerosis
Protease activated receptors (PAR)-1 and -2 mediate cellular effects of factor VII activating protease (FSAP).
Atherosclerosis
Protease imaging of human atheromata captures molecular information of atherosclerosis, complementing anatomic imaging.
Atherosclerosis
Protease Inhibitor-Associated Dyslipidemia in HIV-Infected Patients Is Strongly Influenced by the APOA5-1131T->C Gene Variation.
Atherosclerosis
Recent Developments regarding Human Immunodeficiency Virus Infection and Stroke.
Atherosclerosis
Ritonavir binds to and downregulates estrogen receptors: Molecular mechanism of promoting early atherosclerosis.
Atherosclerosis
Ritonavir-induced lipoatrophy and dyslipidaemia is reversed by the anti-inflammatory drug leflunomide in a PPAR-?-dependent manner.
Atherosclerosis
Rosuvastatin Improves Vaspin Serum Levels in Obese Patients with Acute Coronary Syndrome.
Atherosclerosis
Secretory leukocyte protease inhibitor promising protective roles in obesity-associated atherosclerosis.
Atherosclerosis
Sequence variations in PCSK9, low LDL, and protection against coronary heart disease.
Atherosclerosis
ST-elevation myocardial infarction due to a spontaneous thrombus in the left anterior descending artery in a young HIV-infected patient.
Atherosclerosis
SUMO-specific protease 2 (SENP2) suppresses keratinocyte migration by targeting NDR1 for de-SUMOylation.
Atherosclerosis
Targeting Coagulation Factor Xa Promotes Regression of Advanced Atherosclerosis in Apolipoprotein-E Deficient Mice.
Atherosclerosis
The expression of a disintegrin and metalloproteinase with thrombospondin motifs 4 in human macrophages is inhibited by the anti-atherogenic cytokine transforming growth factor-? and requires Smads, p38 mitogen-activated protein kinase and c-Jun.
Atherosclerosis
The Factor VII-activating Protease (FSAP) Enhances the Activity of Bone Morphogenetic Protein-2 (BMP-2).
Atherosclerosis
Therapeutical potential of direct thrombin inhibitors for atherosclerotic vascular disease.
Atherosclerosis
Therapies targeting innate immunity for fighting inflammation in atherosclerosis.
Atherosclerosis
Thrombin and its protease-activated receptor-1 (PAR1) participate in the endothelial-mesenchymal transdifferentiation process.
Atherosclerosis
Thrombin regulates expression of monocyte chemoattractant protein-1 in vascular smooth muscle cells.
Atherosclerosis
Thrombin regulates vascular smooth muscle cell proteoglycan synthesis via PAR-1 and multiple downstream signalling pathways.
Atherosclerosis
Thrombin stimulates smooth muscle cell procollagen synthesis and mRNA levels via a PAR-1 mediated mechanism.
Atherosclerosis
Topology of protease activities reflects atherothrombotic plaque complexity.
Atherosclerosis
Unusual Response of Subclavian In-Stent Restenosis to Balloon Angioplasty in a Patient with HIV.
Atherosclerosis
USP20 (Ubiquitin-Specific Protease 20) Inhibits TNF (Tumor Necrosis Factor)-Triggered Smooth Muscle Cell Inflammation and Attenuates Atherosclerosis.
Atherosclerosis
Visceral adipose tissue-derived serine protease inhibitor accelerates cholesterol efflux by up-regulating ABCA1 expression via the NF-?B/miR-33a pathway in THP-1 macropahge-derived foam cells.
Atherosclerosis
Vitamin D insufficiency is associated with subclinical atherosclerosis in HIV-1-infected patients on combination antiretroviral therapy.
Atherosclerosis
[Acute myocardial infarct in HIV-positive patients in treatment with protease inhibitors]
Atherosclerosis
[Lipodystrophy and lipid metabolism alterations in HIV-infected patients receiving highly active antiretroviral therapy (HAART)]
Atrial Fibrillation
Prognostic value of plasma von Willebrand factor and its cleaving protease ADAMTS13 in patients with atrial fibrillation.
Atrial Fibrillation
Successful co-administration of dabigatran etexilate and protease inhibitors ritonavir/lopinavir in a patient with atrial fibrillation.
Atypical Hemolytic Uremic Syndrome
MASP2 levels are elevated in thrombotic microangiopathies: association with microvascular endothelial cell injury and suppression by anti-MASP2 antibody narsoplimab.
Atypical Squamous Cells of the Cervix
Yeast mating and image-based quantification of spatial pattern formation.
Autoimmune Diseases
alpha-enolase, a novel strong plasmin(ogen) binding protein on the surface of pathogenic streptococci.
Autoimmune Diseases
Anti-Factor H autoantibodies associated with atypical hemolytic uremic syndrome.
Autoimmune Diseases
Cathepsin V is involved in the degradation of invariant chain in human thymus and is overexpressed in myasthenia gravis.
Autoimmune Diseases
Characterization of the CD177 interaction with the ANCA antigen proteinase 3.
Autoimmune Diseases
Cloning, expression analysis and enzymatic characterization of cathepsin S from olive flounder (Paralichthys olivaceus).
Autoimmune Diseases
Concentration and Subclass Distribution of Anti-ADAMTS13 IgG Autoantibodies in Different Stages of Acquired Idiopathic Thrombotic Thrombocytopenic Purpura.
Autoimmune Diseases
Differences in SpeB protease activity among group A streptococci associated with superficial, invasive, and autoimmune disease.
Autoimmune Diseases
Effect of FUT-175, a new synthetic protease inhibitor, on the development of lupus nephritis in (NZB x NZW) F1 mice.
Autoimmune Diseases
Effect of recombinant Trichinella spiralis cysteine proteinase inhibitor on TNBS-induced experimental inflammatory bowel disease in mice.
Autoimmune Diseases
Granzyme B is dispensable for immunologic tolerance to self in a murine model of systemic lupus erythematosus.
Autoimmune Diseases
In vivo imaging of HIV protease activity in amplicon vector-transduced gliomas.
Autoimmune Diseases
Polymorphisms in the gene encoding thymus-specific serine protease in the extended HLA complex: a potential candidate gene for autoimmune and HLA-associated diseases.
Autoimmune Diseases
Role of Malt1 protease activity in pathogenesis of inflammatory disorders mediated by Fc?R signaling.
Autoimmune Diseases
Role of serine proteases in inflammation: Bowman-Birk protease inhibitor (BBI) as a potential therapy for autoimmune diseases.
Autoimmune Diseases
Self-assembled hybrid supraparticles that proteolytically degrade tumor necrosis factor-?.
Autoimmune Diseases
Substrate-derived triazolo- and azapeptides as inhibitors of cathepsins K and S.
Autoimmune Diseases
Sustained expression of circulating human alpha-1 antitrypsin reduces inflammation, increases CD4+FoxP3+ Treg cell population and prevents signs of experimental autoimmune encephalomyelitis in mice.
Autoimmune Diseases
The role of human leukocyte antigen DRB1-DQB1 haplotypes in the susceptibility to acquired idiopathic thrombotic thrombocytopenic purpura.
Autoimmune Diseases
Tuberculosis, onychomycosis and immune deficiency in complicated Crohn's disease.
Autoimmune Diseases
Unique conformation of cancer autoantigen B23 in hepatoma: a mechanism for specificity in the autoimmune response.
Autoimmune Diseases
Von Willebrand factor cleaving protease (ADAMTS-13) in 123 patients with connective tissue diseases (systemic lupus erythematosus and systemic sclerosis).
Avian Leukosis
Reverse transcriptase and protease activities of avian leukosis virus Gag-Pol fusion proteins expressed in insect cells.
Azoospermia
Mutations in the chromosome pairing gene FKBP6 are not a common cause of non-obstructive azoospermia.
Azoospermia
Novel mutations in testis-specific ubiquitin protease 26 gene may cause male infertility and hypogonadism.
Azoospermia
The value of epididymal protease inhibitor in differential diagnosis between obstructive azoospermia and non-obstructive azoospermia.
Azotemia
Urine proteome scans uncover total urinary protease, prostaglandin D synthase, serum amyloid P, and superoxide dismutase as potential markers of lupus nephritis.
Babesiosis
In Vitro Mode of Action and Anti-thrombotic Activity of Boophilin, a Multifunctional Kunitz Protease Inhibitor from the Midgut of a Tick Vector of Babesiosis, Rhipicephalus microplus.
Bacteremia
A synthetic M protein peptide synergizes with a CXC chemokine protease to induce vaccine-mediated protection against virulent streptococcal pyoderma and bacteremia.
Bacteremia
Bacterial and host factors affecting Pseudomonas aeruginosa colonization versus bacteremia in granulocytopenic patients.
Bacteremia
Histopathologic changes in kidney and liver correlate with streptococcal pyrogenic exotoxin B production in the mouse model of group A streptococcal infection.
Bacteremia
Impact of Vancomycin on sarA-Mediated Biofilm Formation: Role in Persistent Endovascular Infections Due to Methicillin-Resistant Staphylococcus aureus.
Bacteremia
Serum antibody concentrations of cytotoxin, exotoxin, A, lipopolysaccharide, protease, and elastase and survival of patients with Pseudomonas aeruginosa bacteremia.
Bacterial Infections
A novel FRET peptide assay reveals efficient Helicobacter pylori HtrA inhibition through zinc and copper binding.
Bacterial Infections
A Serine Protease Homolog Negatively Regulates TEP1 Consumption in Systemic Infections of the Malaria Vector Anopheles gambiae.
Bacterial Infections
Bifunctional Probes of Cathepsin Protease Activity and pH Reveal Alterations in Endolysosomal pH during Bacterial Infection.
Bacterial Infections
Cathepsin B of Cynoglossus semilaevis: identification, expression, and activity analysis.
Bacterial Infections
Characterization of rabbit corneal damage produced by Serratia keratitis and by a serratia protease.
Bacterial Infections
Clip domain prophenoloxidase activating protease is required for Ostrinia furnacalis Guenée to defend against bacterial infection.
Bacterial Infections
Cytochemical determination of intracellular polymorphonuclear leukocyte elastase content in patients with severe bacterial infection and septicaemia correlated with coagulation parameters.
Bacterial Infections
Disk abalone (Haliotis discus discus) expresses a novel antistasin-like serine protease inhibitor: Molecular cloning and immune response against bacterial infection.
Bacterial Infections
Effects of elastase, protease and common antigen (OEP) from Pseudomonas aeruginosa on protection against burns in mice.
Bacterial Infections
Evaluation of microbial enzymes in normal and abnormal cervicovaginal fluids of cervical dysplasia: a case control study.
Bacterial Infections
Expression characterization and activity analysis of a cathepsin B from Pacific abalone Haliotis discus hannai.
Bacterial Infections
Functional characterization of a ficolin-mediated complement pathway in amphioxus.
Bacterial Infections
Genetic and biochemical characterization of PrtA, an RTX-like metalloprotease from Photorhabdus.
Bacterial Infections
Neutrophil and Monocyte Function in Patients with Chronic Hepatitis C Undergoing Antiviral Therapy with Regimens Containing Protease Inhibitors with and without Interferon.
Bacterial Infections
Neutrophil Elastase Modulates Cytokine Expression: Contribution to Host defense against Pseudomonas aeruginosa-induced Pneumonia.
Bacterial Infections
Plasma fractionation in countries with limited infrastructure and low-/medium income: How to move forward?
Bacterial Infections
Protease activity sensors noninvasively classify bacterial infections and antibiotic responses.
Bacterial Infections
Protease-cleaved iron-transferrin augments oxidant-mediated endothelial cell injury via hydroxyl radical formation.
Bacterial Infections
Protein regions important for plasminogen activation and inactivation of alpha2-antiplasmin in the surface protease Pla of Yersinia pestis.
Bacterial Infections
Structural Basis for the Inhibition Mechanism of Ecotin against Neutrophil Elastase by Targeting the Active Site and Secondary Binding Site.
Bacterial Infections
Surfactant protein A enhances production of secretory leukoprotease inhibitor and protects it from cleavage by matrix metalloproteinases.
Bacterial Infections
Tackling Pseudomonas aeruginosa Virulence by a Hydroxamic Acid-Based LasB Inhibitor.
Bacterial Infections
Targeting secretory leukocyte protease inhibitor (SLPI) inhibits colorectal cancer cell growth, migration and invasion via downregulation of AKT.
Bacterial Infections
Ultrasonic examination of differences in bone density of chronic obstructive pulmonary disease (COPD) rats constructed by different methods.
Bacteroides Infections
Purification and characterization of a fibrinogen-degrading protease in Bacteroides fragilis strain YCH46.
Bartonella Infections
IrSPI, a tick serine protease inhibitor involved in tick feeding and Bartonella henselae infection.
beta-galactosidase deficiency
Effects of thiol protease inhibitors on intracellular degradation of exogenous beta-galactosidase in cultured human skin fibroblasts.
beta-n-acetylhexosaminidase deficiency
Molecular heterogeneity in lysosomal storage diseases. Alpha-fucosidase and N-acetyl-beta-D-hexosaminidase deficiency variants.
beta-Thalassemia
Plasma levels of the von Willebrand factor-cleaving protease in physiological and pathological conditions in children.
Bile Reflux
Physiology and pathophysiology of bicarbonate secretion by pancreatic duct epithelium.
Blister
Calpain activation in plasma membrane bleb formation during tert-butyl hydroperoxide-induced rat hepatocyte injury.
Blister
Characteristic Pattern of IL-17RA, IL-17RB, and IL-17RC in Monocytes/Macrophages and Mast Cells From Patients With Bullous Pemphigoid.
Blister
Demonstration of collagenase and elastase activities in the blister fluids from bullous skin diseases. Comparison between dermatitis herpetiformis and bullous pemphigoid.
Blister
Insulin-like growth factors (IGFs) and IGF-binding proteins in human skin interstitial fluid.
Blister
Laminin in the cutaneous basement membrane as a potential target in lewisite vesication.
Blister
Molecular determination of laminin-5 degradation: a biomarker for mustard gas exposure diagnosis and its mechanism of action.
Blister
Origin and properties of the blister formation factor in blister fluids from recessive dystrophic epidermolysis bullosa.
Blister
Plasmin Plays a Role in the In Vitro Generation of the Linear IgA Dermatosis Antigen LADB97.
Blister
Platelet adhesion enhances the glycoprotein VI-dependent procoagulant response: Involvement of p38 MAP kinase and calpain.
Blister
Protease inhibitor therapy for recessive dystrophic epidermolysis bullosa. In vitro effect and clinical trial with camostat mesylate.
Blister
Putative role of proteolysis and inflammatory response in the toxicity of nerve and blister chemical warfare agents: implications for multi-threat medical countermeasures.
Blister
Supported Planar Mammalian Membranes as Models of in vivo Cell Surface Architectures.
Blood Coagulation Disorders
Effect of umbelliferone (7-hydroxycoumarin, 7-HOC) on the enzymatic, edematogenic and necrotic activities of secretory phospholipase A2 (sPLA2) isolated from Crotalus durissus collilineatus venom.
Blood Coagulation Disorders
Microbial serine protease inhibitors and their therapeutic applications.
Bloom Syndrome
Protease inhibitors reduce the frequency of spontaneous chromosome abnormalities in cells from patients with Bloom syndrome.
Bone Cysts
Jak1-STAT3 Signals Are Essential Effectors of the USP6/TRE17 Oncogene in Tumorigenesis.
Bone Cysts
TRE17/ubiquitin-specific protease 6 (USP6) oncogene translocated in aneurysmal bone cyst blocks osteoblastic maturation via an autocrine mechanism involving bone morphogenetic protein dysregulation.
Bone Cysts
USP6 Confers Sensitivity to IFN-Mediated Apoptosis through Modulation of TRAIL Signaling in Ewing Sarcoma.
Bone Cysts
Validation of Fluorescence in situ Hybridization Testing of USP6 Gene Rearrangement for Diagnosis of Primary Aneurysmal Bone Cyst.
Bone Diseases
Tenofovir-Associated Bone Adverse Outcomes among a US National Historical Cohort of HIV-Infected Veterans: Risk Modification by Concomitant Antiretrovirals.
Bone Diseases, Developmental
FAM111 protease activity undermines cellular fitness and is amplified by gain-of-function mutations in human disease.
Bone Diseases, Developmental
The role of calcium-sensing receptor signaling in regulating transepithelial calcium transport.
Bone Diseases, Metabolic
Accelerated bone mineral loss in HIV-infected patients receiving potent antiretroviral therapy.
Bone Diseases, Metabolic
Effects of switching to protease inhibitor monotherapy on nucleoside analogue-related adverse events.
Bone Diseases, Metabolic
HIV envelope gp120-mediated regulation of osteoclastogenesis via receptor activator of nuclear factor kappa B ligand (RANKL) secretion and its modulation by certain HIV protease inhibitors through interferon-gamma/RANKL cross-talk.
Bone Diseases, Metabolic
Osteopenia in HIV-infected men: association with asymptomatic lactic acidemia and lower weight pre-antiretroviral therapy.
Bone Diseases, Metabolic
Osteopenia in HIV-infected women prior to highly active antiretroviral therapy.
Bone Diseases, Metabolic
Relationship between low bone mineral density and highly active antiretroviral therapy including protease inhibitors in HIV-infected patients.
Bone Resorption
AP-1 and Mitf interact with NFATc1 to stimulate cathepsin K promoter activity in osteoclast precursors.
Bone Resorption
Discovery of a New Class of Cathepsin K Inhibitors in Rhizoma Drynariae as Potential Candidates for the Treatment of Osteoporosis.
Bone Resorption
Everolimus suppresses cancellous bone loss, bone resorption, and cathepsin K expression by osteoclasts.
Bone Resorption
Expression of the thrombin receptor in developing bone and associated tissues.
Bone Resorption
HIV envelope gp120-mediated regulation of osteoclastogenesis via receptor activator of nuclear factor kappa B ligand (RANKL) secretion and its modulation by certain HIV protease inhibitors through interferon-gamma/RANKL cross-talk.
Bone Resorption
IL-1alpha stimulates cathepsin K expression in osteoclasts via the tyrosine kinase-NF-kappaB pathway.
Bone Resorption
Impaired bone resorption in cathepsin K-deficient mice is partially compensated for by enhanced osteoclastogenesis and increased expression of other proteases via an increased RANKL/OPG ratio.
Bone Resorption
Inhibitory Effects of 2N1HIA (2-(3-(2-Fluoro-4-Methoxyphenyl)-6-Oxo-1(6H)-Pyridazinyl)-N-1H-Indol-5-Ylacetamide) on Osteoclast Differentiation via Suppressing Cathepsin K Expression.
Bone Resorption
Inhibitory Effects of N-[2-(4-acetyl-1-piperazinyl) phenyl]-2-(2-chlorophenoxy) acetamide on Osteoclast Differentiation In Vitro via the Downregulation of TRAF6.
Bone Resorption
Interferon-gamma down-regulates gene expression of cathepsin K in osteoclasts and inhibits osteoclast formation.
Bone Resorption
Localization of rat cathepsin K in osteoclasts and resorption pits: inhibition of bone resorption and cathepsin K-activity by peptidyl vinyl sulfones.
Bone Resorption
Modulation by soluble factors of gelatinase activities released by osteoblastic cells.
Bone Resorption
Optical tomographic imaging discriminates between disease-modifying anti-rheumatic drug (DMARD) and non-DMARD efficacy in collagen antibody-induced arthritis.
Bone Resorption
Optimized transfection of diced siRNA into mature primary human osteoclasts: inhibition of cathepsin K mediated bone resorption by siRNA.
Bone Resorption
Porphyromonas gulae Has Virulence and Immunological Characteristics Similar to Those of the Human Periodontal Pathogen Porphyromonas gingivalis.
Bone Resorption
Potent and selective cathepsin L inhibitors do not inhibit human osteoclast resorption in vitro.
Bone Resorption
Proteolytic activity of human osteoclast cathepsin K. Expression, purification, activation, and substrate identification.
Bone Resorption
RANK ligand and interferon gamma differentially regulate cathepsin gene expression in pre-osteoclastic cells.
Bone Resorption
Rat cathepsin K: Enzymatic specificity and regulation of its collagenolytic activity.
Bone Resorption
Reduced bone mineral density in human immunodeficiency virus-infected patients and its association with increased central adiposity and postload hyperglycemia.
Bone Resorption
Role of NOD1 polymorphism in susceptibility and clinical progression of rheumatoid arthritis.
Bone Resorption
Selective anabolic effects of muteins of mid-region PTH fragments on skeletal tissues of prepubertal rats.
Bone Resorption
Study of the functional share of lysosomal cathepsins by the development of specific inhibitors.
Bone Resorption
V-ATPase subunit ATP6AP1 (Ac45) regulates osteoclast differentiation, extracellular acidification, lysosomal trafficking, and protease exocytosis in osteoclast-mediated bone resorption.
Bone Resorption
[Effects of protease inhibitors and protein synthesis inhibitors on cartilage tissue-dependent bone resorption]
Bone Resorption
[Regulation of bone metabolism in osteoporosis : novel drugs for osteoporosis in development].
Botulism
Adeno-associated virus transfer of a gene encoding SNAP-25 resistant to botulinum toxin A attenuates neuromuscular paralysis associated with botulism.
Botulism
Evaluation of adamantane hydroxamates as botulinum neurotoxin inhibitors: synthesis, crystallography, modeling, kinetic and cellular based studies.
Botulism
Iterative structure-based peptide-like inhibitor design against the botulinum neurotoxin serotype A.
Botulism
Rescue of exocytosis in botulinum toxin A-poisoned chromaffin cells by expression of cleavage-resistant SNAP-25. Identification of the minimal essential C-terminal residues.
Botulism
Retargeting Clostridium difficile Toxin B to Neuronal Cells as a Potential Vehicle for Cytosolic Delivery of Therapeutic Biomolecules to Treat Botulism.
Botulism
Synthesis and evaluation of library of betulin derivatives against the botulinum neurotoxin A protease.
Boutonneuse Fever
Rickettsia conorii infection stimulates the expression of ISG15 and ISG15 protease UBP43 in human microvascular endothelial cells.
Brain Death
Protective effects of urinary trypsin inhibitor (UTI) on hepatic microvasculature in hypotensive brain-dead rats.
Brain Diseases
A quantitative and qualitative analysis of prion protein immunohistochemical staining in Creutzfeldt-Jakob disease using four anti prion protein antibodies.
Brain Diseases
Characterisation of new monoclonal antibodies reacting with prions from both human and animal brain tissues.
Brain Diseases
CJD PrPsc removal by nanofiltration process: application to a therapeutic immunoglobulin solution (Lymphoglobuline).
Brain Diseases
Effects of clioquinol on memory impairment and the neurochemical modifications induced by scrapie infection in golden hamsters.
Brain Diseases
Four types of scrapie in goats differentiated from each other and bovine spongiform encephalopathy by biochemical methods.
Brain Diseases
Functional and dysfunctional conformers of human neuroserpin characterized by optical spectroscopies and Molecular Dynamics.
Brain Diseases
G392E neuroserpin causing the dementia FENIB is secreted from cells but is not synaptotoxic.
Brain Diseases
LONP1 de novo dominant mutation causes mitochondrial encephalopathy with loss of LONP1 chaperone activity and excessive LONP1 proteolytic activity.
Brain Diseases
Low Bone Mineral Density in Vertically HIV-Infected Children and Adolescents: Risk Factors and the Role of T-Cell Activation and Senescence.
Brain Diseases
Lysosomal and nonlysosomal protease activities of the brain in response to ethanol feeding.
Brain Diseases
Mapping of possible prion protein self-interaction domains using peptide arrays.
Brain Diseases
Metabotropic glutamate receptor/phospholipase C pathway: a vulnerable target to Creutzfeldt-Jakob disease in the cerebral cortex.
Brain Diseases
Molecular characteristics of a protease-resistant, amyloidogenic and neurotoxic peptide homologous to residues 106-126 of the prion protein.
Brain Diseases
Natural Biomolecules and Protein Aggregation: Emerging Strategies against Amyloidogenesis.
Brain Diseases
Progressive myoclonic epilepsy associated with neuroserpin inclusion bodies (neuroserpinosis).
Brain Diseases
Protease-resistant prion protein in brain and lymphoid organs of sheep within a naturally scrapie-infected flock.
Brain Diseases
Regression of HIV encephalopathy and basal ganglia signal intensity abnormality at MR imaging in patients with AIDS after the initiation of protease inhibitor therapy.
Brain Diseases
Regression of HIV-associated progressive encephalopathy of childhood during HAART.
Brain Diseases
Screening a library of potential prion therapeutics against cellular prion proteins and insights into their mode of biological activities by surface plasmon resonance.
Brain Diseases
Sequential appearance and accumulation of pathognomonic markers in the central nervous system of hamsters orally infected with scrapie.
Brain Diseases
Sites of prion protein accumulation in scrapie-infected mouse spleen revealed by immuno-electron microscopy.
Brain Diseases
Synthesis and SAR study of acridine, 2-methylquinoline and 2-phenylquinazoline analogues as anti-prion agents.
Brain Diseases
The architecture of prions: how understanding would provide new therapeutic insights.
Brain Diseases
The entry of antiviral and antiretroviral drugs into the central nervous system.
Brain Diseases
Two-dimensional mapping of three phenotype-associated isoforms of the prion protein in sporadic Creutzfeldt-Jakob disease.
Brain Diseases
[182 offspring of cows with bovine spongiform encephalopathy (BSE) in Switzerland. 2. Epidemiology and pathological findings]
Brain Edema
Effects of focal mild hypothermia on thrombin-induced brain edema formation and the expression of protease activated receptor-1, matrix metalloproteinase-9 and aquaporin 4 in rats.
Brain Edema
Epsilon Aminocaproic Acid Pretreatment Provides Neuroprotection Following Surgically Induced Brain Injury in a Rat Model.
Brain Edema
Induction of colligin may attenuate brain edema following intracerebral hemorrhage.
Brain Edema
Serine protease inhibitor attenuates intracerebral hemorrhage-induced brain injury and edema formation in rat.
Brain Edema
The expression and the role of protease nexin-1 on brain edema after intracerebral hemorrhage.
Brain Edema
[Effect of agents increasing the resistance of the vascular wall as well as of trasylol (a protease inhibitor) on experimental brain edema]
Brain Injuries
3K3A-activated protein C blocks amyloidogenic BACE1 pathway and improves functional outcome in mice.
Brain Injuries
Deficiency in serine protease inhibitor neuroserpin exacerbates ischemic brain injury by increased postischemic inflammation.
Brain Injuries
Delayed treatment with ADAMTS13 ameliorates cerebral ischemic injury without hemorrhagic complication.
Brain Injuries
Effect of serine protease inhibitors on posttraumatic brain injury and neuronal apoptosis.
Brain Injuries
Effects of hypothermia on neonatal hypoxic-ischemic brain injury in the rat: phosphorylation of Akt, activation of caspase-3-like protease.
Brain Injuries
Hypoxia-ischemia or excitotoxin-induced tissue plasminogen activator- dependent gelatinase activation in mice neonate brain microvessels.
Brain Injuries
LEX032, a novel recombinant serpin, protects the brain after transient focal ischemia.
Brain Injuries
Mannan binding lectin-associated serine protease-2 (MASP-2) critically contributes to post-ischemic brain injury independent of MASP-1.
Brain Injuries
Neuroprotection against hypoxic-ischemic brain injury by inhibiting the apoptotic protease activating factor-1 pathway.
Brain Injuries
Programmed cell life: anti-apoptotic signaling and therapeutic strategies for neurodegenerative disorders.
Brain Injuries
Regulation of neurons and astrocytes by thrombin and protease nexin-1. Relationship to brain injury.
Brain Injuries
Regulation of protease nexin-1 synthesis and secretion in cultured brain cells by injury-related factors.
Brain Injuries
Serine protease inhibitor attenuates intracerebral hemorrhage-induced brain injury and edema formation in rat.
Brain Injuries
Sinomenine inhibits microglia activation and attenuates brain injury in intracerebral hemorrhage.
Brain Injuries
Taming neonatal hypoxic-ischemic brain injury by intranasal delivery of plasminogen activator inhibitor-1.
Brain Injuries
The Protective Roles of Urinary Trypsin Inhibitor in Brain Injury Following Fat Embolism Syndrome in a Rat Model.
Brain Injuries
Transient receptor potential canonical 3 (TRPC3) mediates thrombin-induced astrocyte activation and upregulates its own expression in cortical astrocytes.
Brain Injuries
Translocation of the serine protease Omi/HtrA2 from mitochondria into the cytosol upon seizure-induced hippocampal injury in the neonatal rat brain.
Brain Injuries, Traumatic
Calpain mediates proteolysis of the voltage-gated sodium channel alpha-subunit.
Brain Injuries, Traumatic
Controlled cortical impact-induced neurodegeneration decreases after administration of the novel calpain-inhibitor Gabadur.
Brain Injuries, Traumatic
Distinct roles for metalloproteinases during traumatic brain injury.
Brain Injuries, Traumatic
Proteolysis of multiple myelin basic protein isoforms after neurotrauma: characterization by mass spectrometry.
Brain Injuries, Traumatic
Ulinastatin alleviates traumatic brain injury by reducing endothelin-1.
Brain Ischemia
Activated protein C inhibits tissue plasminogen activator-induced brain hemorrhage.
Brain Ischemia
Activation systems for latent matrix metalloproteinase-2 are upregulated immediately after focal cerebral ischemia.
Brain Ischemia
Altered biosynthesis of neuropeptide processing enzyme carboxypeptidase E after brain ischemia: molecular mechanism and implication.
Brain Ischemia
Calpain activation induced by glucose deprivation is mediated by oxidative stress and contributes to neuronal damage.
Brain Ischemia
Caspase-3 contributes to ZO-1 and Cl-5 tight-junction disruption in rapid anoxic neurovascular unit damage.
Brain Ischemia
Cleaved caspase-3 expression after experimental stroke exhibits different phenotypes and is predominantly non-apoptotic.
Brain Ischemia
Dipeptidyl peptidase IV, aminopeptidase N and DPIV/APN-like proteases in cerebral ischemia.
Brain Ischemia
Does Na?/Ca²? exchanger, NCX, represent a new druggable target in stroke intervention?
Brain Ischemia
Effect of serine protease inhibitors on posttraumatic brain injury and neuronal apoptosis.
Brain Ischemia
Increase of prothrombin-mRNA after global cerebral ischemia in rats, with constant expression of protease nexin-1 and protease-activated receptors.
Brain Ischemia
Involvement of matrix metalloproteinase in neuroblast cell migration from the subventricular zone after stroke.
Brain Ischemia
Ischemic neuronal death in the rat hippocampus: the calpain-calpastatin-caspase hypothesis.
Brain Ischemia
Microglial activation and matrix protease generation during focal cerebral ischemia.
Brain Ischemia
Nafamostat mesilate attenuates neuronal damage in a rat model of transient focal cerebral ischemia through thrombin inhibition.
Brain Ischemia
Nafamostat mesilate protects against acute cerebral ischemia via blood-brain barrier protection.
Brain Ischemia
Neutrophil elastase mediates acute pathogenesis and is a determinant of long-term behavioral recovery after traumatic injury to the immature brain.
Brain Ischemia
Preconditioning with thrombin can be protective or worsen damage after endothelin-1-induced focal ischemia in rats.
Brain Ischemia
Protease inhibitors for delayed cerebral ischemia after subarachnoid haemorrhage?
Brain Ischemia
Protease Omi cleaving Hax-1 protein contributes to OGD/R-induced mitochondrial damage in neuroblastoma N2a cells and cerebral injury in MCAO mice.
Brain Ischemia
Protective effects of calpain inhibitors against neuronal damage caused by cytotoxic hypoxia in vitro and ischemia in vivo.
Brain Ischemia
Six-hour window of opportunity for calpain inhibition in focal cerebral ischemia in rats.
Brain Ischemia
Targeted disruption of SPI3/Serpinb6 does not result in developmental or growth defects, leukocyte dysfunction, or susceptibility to stroke.
Brain Ischemia
The protease thrombin is an endogenous mediator of hippocampal neuroprotection against ischemia at low concentrations but causes degeneration at high concentrations.
Brain Neoplasms
A pharmacologic inhibitor of the protease Taspase1 effectively inhibits breast and brain tumor growth.
Brain Neoplasms
c-Myc regulates the coordinated transcription of brain disease-related PDCD10-SERPINI1 bidirectional gene pair.
Brain Neoplasms
Cellular localization and enzymatic activity of cathepsin B after spinal cord injury in the rat.
Brain Neoplasms
Detection of cathepsin S cysteine protease in human brain tumour microdialysates in vivo.
Brain Neoplasms
Down-regulation of cathepsin B expression impairs the invasive and tumorigenic potential of human glioblastoma cells.
Brain Neoplasms
Effects of fixation time and enzymatic digestion on immunohistochemical demonstration of bromodeoxyuridine in formalin-fixed, paraffin-embedded tissue.
Brain Neoplasms
Expression of ADAMTS-8, a secreted protease with antiangiogenic properties, is downregulated in brain tumours.
Brain Neoplasms
Immunohistochemical demonstration of bikunin, a light chain of inter-alpha-trypsin inhibitor, in human brain tumors.
Brain Neoplasms
Immunoreactivity, ultrastructural localization, and transcript expression of prostate-specific antigen in human neuroblastoma cell lines.
Brain Neoplasms
Protease Responsive Nanogels for Transcytosis across the Blood-Brain Barrier and Intracellular Delivery of Radiopharmaceuticals to Brain Tumor Cells.
Brain Neoplasms
Serpin inhibitors of urokinase and thrombin in normal rat brain and the 9L brain tumor: evidence for elevated expression of protease nexin I-like inhibitor and a novel sodium dodecyl sulfate-activated tumor antithrombin.
Brain Neoplasms
The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cells.
Breast Diseases
Serum total and free prostate-specific antigen for breast cancer diagnosis in women.
Breast Neoplasms
A Novel Role for Cathepsin S as a Potential Biomarker in Triple Negative Breast Cancer.
Breast Neoplasms
A prospective study of the prognostic value of cathepsin D levels in breast cancer cytosol.
Breast Neoplasms
A proteolytic activity in a human breast cancer cell line which is inhibited by the anticarcinogenic Bowman-Birk protease inhibitor.
Breast Neoplasms
A review of nanoparticle drug delivery systems responsive to endogenous breast cancer microenvironment.
Breast Neoplasms
Absence of specific cell-surface binding of tissue plasminogen activator in uterine cells.
Breast Neoplasms
Activated protein C enhances cell motility of endothelial cells and MDA-MB-231 breast cancer cells by intracellular signal transduction.
Breast Neoplasms
ADAM protease inhibition overcomes resistance of breast cancer stem-like cells to ?? T cell immunotherapy.
Breast Neoplasms
ADAMTS1 Promotes Adhesion to Extracellular Matrix Proteins and Predicts Prognosis in Early Stage Breast Cancer Patients.
Breast Neoplasms
Adenoviral-mediated expression of human insulin-like growth factor-binding protein-3.
Breast Neoplasms
alpha 1-Antitrypsin- and anchorage-independent growth of MCF-7 breast cancer cells.
Breast Neoplasms
An emerging role for the nuclear localization of maspin in the suppression of tumor progression and metastasis (1) (1) This article is part of Special Issue entitled Asilomar Chromatin and has undergone the Journal's usual peer review process.
Breast Neoplasms
An investigation of the relationship between TMPRSS6 gene expression, genetic variants and clinical findings in breast cancer.
Breast Neoplasms
Analysis of breast-tissue cathepsin-d isoforms from patients with breast-cancer, benign breast disease and from normal controls.
Breast Neoplasms
Apoptosis and lysosome membrane permeabilization induction on breast cancer cells by an anticarcinogenic Bowman-Birk protease inhibitor from Vigna unguiculata seeds.
Breast Neoplasms
Association between high concentrations of Mr 52,000 cathepsin D and poor prognosis in primary human breast cancer.
Breast Neoplasms
Autophagy-related genes are induced by histone deacetylase inhibitor suberoylanilide hydroxamic acid via the activation of cathepsin B in human breast cancer cells.
Breast Neoplasms
Avidin-biotin-peroxidase-antiperoxidase (ABPAP) complex. An immunocytochemical method with enhanced sensitivity.
Breast Neoplasms
Binary and ternary combinations of anti-HIV protease inhibitors: effect on gene expression and functional activity of CYP3A4 and efflux transporters.
Breast Neoplasms
Bioprospecting endophytic fungi from Fusarium genus as sources of bioactive metabolites.
Breast Neoplasms
Bioregulation of kallikrein-related peptidases 6, 10 and 11 by the kinin B? receptor in breast cancer cells.
Breast Neoplasms
Breast cancer cell uptake of the inflammatory mediator neutrophil elastase triggers an anticancer adaptive immune response.
Breast Neoplasms
Breast carcinoma associated protein - a novel binding partner of Mason-Pfizer monkey virus protease.
Breast Neoplasms
Candidate prognostic markers in breast cancer: focus on extracellular proteases and their inhibitors.
Breast Neoplasms
Caspase-3 inhibits the growth of breast cancer cells independent of protease activity.
Breast Neoplasms
Cathepsin D assay in primary breast cancer and lymph nodes: relationship with c-myc, c-erb-B-2 and int-2 oncogene amplification and node invasiveness.
Breast Neoplasms
Cathepsin D concentration in breast cancer cytosols: correlation with biochemical, histological, and clinical findings.
Breast Neoplasms
Cathepsin D deficiency in mammary epithelium transiently stalls breast cancer by interference with mTORC1 signaling.
Breast Neoplasms
Cathepsin D expression detected by immunohistochemistry has independent prognostic value in axillary node-negative breast cancer.
Breast Neoplasms
Cathepsin D gene of human MCF7 cells contains estrogen-responsive sequences in its 5' proximal flanking region.
Breast Neoplasms
Cathepsin D: association between TN-stage and steroid receptor status of breast carcinoma.
Breast Neoplasms
Cathepsin D: newly discovered functions of a long-standing aspartic protease in cancer and apoptosis.
Breast Neoplasms
Cathepsin D: screening for new polymorphisms using single-strand conformation polymorphism analysis.
Breast Neoplasms
Cathepsin G, a neutrophil protease, induces compact cell-cell adhesion in MCF-7 human breast cancer cells.
Breast Neoplasms
Cathepsin V suppresses GATA3 protein expression in luminal A breast cancer.
Breast Neoplasms
Cathepsin-D, a key protease in breast cancer, is up-regulated in obese mouse and human adipose tissue, and controls adipogenesis.
Breast Neoplasms
CCAAT-displacement protein/cut homeobox transcription factor (CUX1) represses estrogen receptor-alpha (ER-?) in triple-negative breast cancer cells and can be antagonized by muscadine grape skin extract (MSKE).
Breast Neoplasms
CD44 crosslinking-mediated matrix metalloproteinase-9 relocation in breast tumor cells leads to enhanced metastasis.
Breast Neoplasms
CD44 enhances invasion of basal-like breast cancer cells by upregulating serine protease and collagen-degrading enzymatic expression and activity.
Breast Neoplasms
Characterization and enumeration of cells secreting tumor markers in the peripheral blood of breast cancer patients.
Breast Neoplasms
Characterization of a novel, membrane-bound, 80-kDa matrix-degrading protease from human breast cancer cells. Monoclonal antibody production, isolation, and localization.
Breast Neoplasms
Characterization of an amino-terminal fragment of insulin-like growth factor binding protein-3 and its effects in MCF-7 breast cancer cells.
Breast Neoplasms
Clinical significance of cathepsin D concentration in tumor cytosol of primary breast cancer.
Breast Neoplasms
Collagenase-3 expression in breast myofibroblasts as a molecular marker of transition of ductal carcinoma in situ lesions to invasive ductal carcinomas.
Breast Neoplasms
Comparative prognostic value of Cathepsin D and urokinase plasminogen activator, detected by immunohistochemistry, in primary breast carcinoma.
Breast Neoplasms
Comparative quantitative immunohistochemical and immunoradiometric determinations of cathepsin D in endometrial adenocarcinoma: predictors of tumor aggressiveness.
Breast Neoplasms
Comprehensive Analysis of the Expression and Prognostic Value of SPINT1/2 in Breast Carcinoma.
Breast Neoplasms
Comprehensive quantitative analysis of ovarian and breast cancer tumor peptidomes.
Breast Neoplasms
Cooperation of tissue factor cytoplasmic domain and PAR2 signaling in breast cancer development.
Breast Neoplasms
Correction: Protease Nexin I is a feedback regulator of EGF/ PKC/MAPK/EGR1 signaling in breast cancer cells metastasis and stemness.
Breast Neoplasms
Correlation of tumor cytosol cathepsin D with differentiation and invasiveness of endometrial adenocarcinoma.
Breast Neoplasms
Crystal structures of native and inhibited forms of human cathepsin D: implications for lysosomal targeting and drug design.
Breast Neoplasms
Cyclin E both regulates and is regulated by calpain 2, a protease associated with metastatic breast cancer phenotype.
Breast Neoplasms
Cyclin E in breast tumors is cleaved into its low molecular weight forms by calpain.
Breast Neoplasms
Cytochrome P450 enzymes and transporters induced by anti-human immunodeficiency virus protease inhibitors in human hepatocytes: implications for predicting clinical drug interactions.
Breast Neoplasms
Decreased secretion of Cathepsin D in breast cancer in vivo by tamoxifen: mediated by the mannose-6-phosphate/IGF-II receptor?
Breast Neoplasms
Degradomics: systems biology of the protease web. Pleiotropic roles of MMPs in cancer.
Breast Neoplasms
Depletion of mitochondrial protease OMA1 alters proliferative properties and promotes metastatic growth of breast cancer cells.
Breast Neoplasms
Deregulated hepsin protease activity confers oncogenicity by concomitantly augmenting HGF/MET signalling and disrupting epithelial cohesion.
Breast Neoplasms
Detection of circulating tumor cells by reverse transcriptase polymerase chain reaction of maspin in patients with breast cancer undergoing conventional-dose chemotherapy.
Breast Neoplasms
Deubiquitinase ubiquitin-specific protease 9X regulates the stability and function of E3 ubiquitin ligase ring finger protein 115 in breast cancer cells.
Breast Neoplasms
Deubiquitinating enzyme USP33/VDU1 is required for Slit signaling in inhibiting breast cancer cell migration.
Breast Neoplasms
Deubiquitylation and stabilization of Notch1 intracellular domain by ubiquitin-specific protease 8 enhance tumorigenesis in breast cancer.
Breast Neoplasms
Development of a selected reaction monitoring mass spectrometry-based assay to detect asparaginyl endopeptidase activity in biological fluids.
Breast Neoplasms
Differences in susceptibility to tumor necrosis factor alpha-induced apoptosis among MCF-7 breast cancer cell variants.
Breast Neoplasms
Differential expression of the mannose 6-phosphate/ insulin-like growth factor-II receptor in human breast cancer cell lines of different invasive potential.
Breast Neoplasms
Differential quantitative proteomics reveals key proteins related to phenotypic changes of breast cancer cells expressing progesterone receptor A.
Breast Neoplasms
Differential regulation of cathepsin D by sex steroids in mammary cancer and uterine cells.
Breast Neoplasms
Differential Regulation of Insulin-Like Growth Factor-Binding Protein-3 Protease Activity in MCF-7 Breast Cancer Cells by Estrogen and Transforming Growth Factor-?1.
Breast Neoplasms
Differential regulation of insulin-like growth factor-binding protein-3 protease activity in MCF-7 breast cancer cells by estrogen and transforming growth factor-beta1.
Breast Neoplasms
Differentially expressed genes regulating the progression of ductal carcinoma in situ to invasive breast cancer.
Breast Neoplasms
Dissociation of solid tumor tissues with cold active protease for single-cell RNA-seq minimizes conserved collagenase-associated stress responses.
Breast Neoplasms
Down regulation of the tumor suppressor gene maspin in breast carcinoma is associated with a higher risk of distant metastasis.
Breast Neoplasms
Down-regulation of cathepsin-D expression by antisense gene transfer inhibits tumor growth and experimental lung metastasis of human breast cancer cells.
Breast Neoplasms
Downregulation of Caspase 8 in a group of Iranian breast cancer patients - A pilot study.
Breast Neoplasms
Downregulation of ER60 Protease Inhibits Cellular Proliferation by Inducing G1/S Arrest in Breast Cancer Cells In Vitro.
Breast Neoplasms
Downregulation of serine protease HTRA1 is associated with poor survival in breast cancer.
Breast Neoplasms
Downregulation of ubiquitin-specific protease 14 (USP14) inhibits breast cancer cell proliferation and metastasis, but promotes apoptosis.
Breast Neoplasms
Downregulation of USP32 inhibits cell proliferation, migration and invasion in human small cell lung cancer.
Breast Neoplasms
Dynamic interactions of cortactin and membrane type 1 matrix metalloproteinase at invadopodia: defining the stages of invadopodia formation and function.
Breast Neoplasms
Dynamic Model of Protease State and Inhibitor Trafficking to Predict Protease Activity in Breast Cancer Cells.
Breast Neoplasms
Dysregulated protease activated receptor 1 (PAR1) promotes metastatic phenotype in breast cancer through HMGA2.
Breast Neoplasms
Early breast cancer screening using iron/iron oxide-based nanoplatforms with sub-femtomolar limits of detection.
Breast Neoplasms
Effects of an Anticarcinogenic Bowman-Birk Protease Inhibitor on Purified 20S Proteasome and MCF-7 Breast Cancer Cells.
Breast Neoplasms
Effects of combined in vivo treatment of transplantable solid mammary carcinoma in wistar rats using vitamin E and cysteine peptidase inhibitors from human placenta.
Breast Neoplasms
Effects of tissue factor, PAR-2 and MMP-9 expression on human breast cancer cell line MCF-7 invasion.
Breast Neoplasms
Effects of treatment with megestrol acetate, aminoglutethimide, or formestane on insulin-like growth factor (IGF) I and II, IGF-binding proteins (IGFBPs), and IGFBP-3 protease status in patients with advanced breast cancer.
Breast Neoplasms
Elafin is downregulated during breast and ovarian tumorigenesis but its residual expression predicts recurrence.
Breast Neoplasms
Elastosis in breast carcinoma: II. Association of protease inhibitors with immature elastic fibres.
Breast Neoplasms
Enzymatically Activated Glyco-Prodrugs of Doxorubicin Synthesized by a Catalysis-Free Diels-Alder Reaction.
Breast Neoplasms
Estradiol-induced biochemical changes in human neoplastic cells: estradiol-mediated protease.
Breast Neoplasms
Estrogens and growth factors induce the mRNA of the 52K-pro-cathepsin-D secreted by breast cancer cells.
Breast Neoplasms
Evaluating the impact of soy compounds on breast cancer using the data mining approach.
Breast Neoplasms
Evidence for tissue factor phosphorylation and its correlation with protease activated receptor expression and the prognosis of primary breast cancer.
Breast Neoplasms
Exome sequencing identifies a recurrent variant in SERPINA3 associating with hereditary susceptibility to breast cancer.
Breast Neoplasms
Expression analysis of maspin in invasive ductal carcinoma of breast and modulation of its expression by curcumin in breast cancer cell lines.
Breast Neoplasms
Expression of a prostate-associated protein, human glandular kallikrein (hK2), in breast tumours and in normal breast secretions.
Breast Neoplasms
Expression of cathepsin D, stromelysin-3, and urokinase by reactive stromal cells on breast carcinoma prognosis.
Breast Neoplasms
Expression of human prostate-specific glandular kallikrein protein (hK2) in the breast cancer cell line T47-D.
Breast Neoplasms
Expression of prostate-specific antigen (PSA) correlates with poor response to tamoxifen therapy in recurrent breast cancer.
Breast Neoplasms
Expression of the serine protease, matriptase, in breast ductal carcinoma of Chinese women: correlation with clinicopathological parameters.
Breast Neoplasms
Extracellular Matrix Components Regulate Bone Sialoprotein Expression in MDA-MB-231 Breast Cancer Cells.
Breast Neoplasms
Extracellular protease mRNAs are predominantly expressed in the stromal areas of microdissected mouse breast carcinomas.
Breast Neoplasms
Fibroblast activation protein-? promotes tumor growth and invasion of breast cancer cells through non-enzymatic functions.
Breast Neoplasms
Fluorescence in situ hybridization assessment of c-myc gene amplification in breast tumor tissues.
Breast Neoplasms
Global Protease Activity Profiling Identifies HER2-Driven Proteolysis in Breast Cancer.
Breast Neoplasms
Hemagglutinin protease secreted by V. cholerae induced apoptosis in breast cancer cells by ROS mediated intrinsic pathway and regresses tumor growth in mice model.
Breast Neoplasms
High expression of testes-specific protease 50 is associated with poor prognosis in colorectal carcinoma.
Breast Neoplasms
HS3ST2 modulates breast cancer cell invasiveness via MAP kinase- and Tcf4 (Tcf7l2)-dependent regulation of protease and cadherin expression.
Breast Neoplasms
Human breast tumor estrogen receptor: effects of molybdate and electrophoretic analyses.
Breast Neoplasms
Hypermethylation and histone deacetylation lead to silencing of the maspin gene in human breast cancer.
Breast Neoplasms
Identification and characterization of a novel matrix-degrading protease from hormone-dependent human breast cancer cells.
Breast Neoplasms
Identification and characterization of the human testes-specific protease 50 gene promoter.
Breast Neoplasms
Identification of a novel aspartic-like protease differentially expressed in human breast cancer cell lines.
Breast Neoplasms
Identification of immunoreactive tissue kallikrein in human ductal breast carcinomas.
Breast Neoplasms
Identification of low-risk node-negative breast cancer patients by tumor biological factors PAI-1 and cathepsin L.
Breast Neoplasms
Identification of potential serum biomarkers for breast cancer using a functional proteomics technology.
Breast Neoplasms
Imaging Matrix Metalloproteinase Activity Implicated in Breast Cancer Progression.
Breast Neoplasms
Immunoenzymatic assay of Mr 52,000 cathepsin D in 182 breast cancer cytosols: low correlation with other prognostic parameters.
Breast Neoplasms
Immunohistochemical distribution of the 52-kDa protein in mammary tumors: a marker associated with cell proliferation rather than with hormone responsiveness.
Breast Neoplasms
Immunohistologic analysis of invasive phenotype in breast carcinoma. A clinicopathologic study.
Breast Neoplasms
Immunonanoparticles--an effective tool to impair harmful proteolysis in invasive breast tumor cells.
Breast Neoplasms
Impact of suppression of tumorigenicity 14 (ST14)/serine protease 14 (prss14) expression analysis on the prognosis and management of estrogen receptor negative breast cancer.
Breast Neoplasms
In vitro degradation of extracellular matrix with Mr 52,000 cathepsin D secreted by breast cancer cells.
Breast Neoplasms
Inactivation of harmful tumour-associated proteolysis by nanoparticulate system.
Breast Neoplasms
Increased plasma cathepsin D concentration in hepatic carcinoma and cirrhosis but not in breast cancer.
Breast Neoplasms
Increased secretory leukocyte protease inhibitor (SLPI) production by highly metastatic mouse breast cancer cells.
Breast Neoplasms
Increased stromal expression of murine urokinase plasminogen activator in a human breast cancer xenograft model following treatment with the matrix metalloprotease inhibitor, batimastat.
Breast Neoplasms
Inhibitory effect of Bowman-Birk protease inhibitor on autophagy in MDAMB231 breast cancer cell line.
Breast Neoplasms
Insulin-like growth factor binding protein (IGFBP)-3 protease activity secreted by MCF-7 breast cancer cells: inhibition by IGFs does not require IGF-IGFBP interaction.
Breast Neoplasms
Isolation and characterization of a trypsin-chymotrypsin inhibitor from the seeds of green lentil (Lens culinaris).
Breast Neoplasms
Isolation and characterization of an inhibitory human monoclonal antibody specific to the urokinase-type plasminogen activator, uPA.
Breast Neoplasms
Isolation and Immuno-Phenotypic Characterization of Tumor Infiltrating Lymphocytes (TILs) Obtained from Breast Malignant Tumor Tissues of Egyptian Patients.
Breast Neoplasms
Isotopic labeling of terminal amines in complex samples identifies protein N-termini and protease cleavage products.
Breast Neoplasms
Kempopeptin C, a Novel Marine-Derived Serine Protease Inhibitor Targeting Invasive Breast Cancer.
Breast Neoplasms
KLK12 is a novel serine protease and a new member of the human kallikrein gene family-differential expression in breast cancer.
Breast Neoplasms
KLK6-regulated miRNA networks activate oncogenic pathways in breast cancer subtypes.
Breast Neoplasms
Knockdown of TSP50 inhibits cell proliferation and induces apoptosis in P19 cells.
Breast Neoplasms
Kunitz type protease inhibitor EgKI-1 from the canine tapeworm Echinococcus granulosus as a promising therapeutic against breast cancer.
Breast Neoplasms
Large-Scale Analysis of Breast Cancer-Related Conformational Changes in Proteins Using Limited Proteolysis.
Breast Neoplasms
Live-Cell Imaging of Protease Activity: Assays to Screen Therapeutic Approaches.
Breast Neoplasms
Low cathepsin D and low plasminogen activator type 1 inhibitor in tumor cytosols defines a group of node negative breast cancer patients with low risk of recurrence.
Breast Neoplasms
Lysosomal cathepsin initiates apoptosis, which is regulated by photodamage to Bcl-2 at mitochondria in photodynamic therapy using a novel photosensitizer, ATX-s10 (Na).
Breast Neoplasms
MALT1 is a critical mediator of PAR1-driven NF-?B activation and metastasis in multiple tumor types.
Breast Neoplasms
Maspin functions as tumor suppressor by increasing cell adhesion to extracellular matrix in prostate tumor cells.
Breast Neoplasms
Maspin gene expression in tumor suppression induced by overexpressing manganese-containing superoxide dismutase cDNA in human breast cancer cells.
Breast Neoplasms
Maspin influences response to doxorubicin by changing the tumor microenvironment organization.
Breast Neoplasms
Maspin, a serpin with tumor-suppressing activity in human mammary epithelial cells.
Breast Neoplasms
Maspin--a novel protease inhibitor with tumor-suppressing activity in breast cancer.
Breast Neoplasms
MCF7 mammary cancer cells respond to bFGF and internalize it following its release from extracellular matrix: a permissive role of cathepsin D.
Breast Neoplasms
Membrane-type 4 matrix metalloproteinase promotes breast cancer growth and metastases.
Breast Neoplasms
Mesotrypsin promotes malignant growth of breast cancer cells through shedding of CD109.
Breast Neoplasms
Metabolism of the vitamin D3 analogue EB1089 alters receptor complex formation and reduces promoter selectivity.
Breast Neoplasms
Methylation and inhibition of expression of uPA by the RAS oncogene: divergence of growth control and invasion in breast cancer cells.
Breast Neoplasms
Microarray and proteomic analysis of breast cancer cell and osteoblast co-cultures: the role of osteoblast matrix metalloproteinase (MMP)-13 in bone metastasis.
Breast Neoplasms
miR-4709-3p Inhibits Cell Proliferation by Downregulating TSP50 Expression in Breast Cancer Cells.
Breast Neoplasms
Modelling of tumour--host coexistence in vitro in the presence of serine protease inhibitors.
Breast Neoplasms
Molecular attributes and apoptosis-inducing activities of a putative serine protease isolated from Tiger Milk mushroom (Lignosus rhinocerus) sclerotium against breast cancer cells in vitro.
Breast Neoplasms
Molecular cloning of cDNA for matriptase, a matrix-degrading serine protease with trypsin-like activity.
Breast Neoplasms
Monitoring protease activity in biological tissues using antibody prodrugs as sensing probes.
Breast Neoplasms
Morphine and breast tumor metastasis: the role of matrix-degrading enzymes.
Breast Neoplasms
Multilectin affinity chromatography for characterization of multiple glycoprotein biomarker candidates in serum from breast cancer patients.
Breast Neoplasms
Multiparametric prognostic evaluation of biological factors in primary breast cancer.
Breast Neoplasms
Multiplex sensing of protease and kinase enzyme activity via orthogonal coupling of quantum dot-peptide conjugates.
Breast Neoplasms
Myoepithelial cell-specific expression of stefin A as a suppressor of early breast cancer invasion.
Breast Neoplasms
Nafamostat mesilate negatively regulates the metastasis of triple-negative breast cancer cells.
Breast Neoplasms
Neutrophil cathepsin G, but not elastase, induces aggregation of MCF-7 mammary carcinoma cells by a protease activity-dependent cell-oriented mechanism.
Breast Neoplasms
Nimbolide inhibits invasion and migration, and down-regulates uPAR chemokine gene expression, in two breast cancer cell lines.
Breast Neoplasms
Nitric oxide regulation of maspin expression in normal mammary epithelial and breast cancer cells.
Breast Neoplasms
Nuclear cathepsin D enhances TRPS1 transcriptional repressor function to regulate cell cycle progression and transformation in human breast cancer cells.
Breast Neoplasms
Optical imaging of spontaneous breast tumors using protease sensing 'smart' optical probes.
Breast Neoplasms
Orally bioavailable small-molecule inhibitor of transcription factor Stat3 regresses human breast and lung cancer xenografts.
Breast Neoplasms
Osteonectin promotes prostate cancer cell migration and invasion: a possible mechanism for metastasis to bone.
Breast Neoplasms
Overview on human breast cancer with focus on prognostic and predictive factors with special attention on the tumour suppressor gene p53.
Breast Neoplasms
PAR-1 mediated apoptosis of breast cancer cells by V. cholerae hemagglutinin protease.
Breast Neoplasms
Pathophysiological functions of cathepsin D: Targeting its catalytic activity versus its protein binding activity?
Breast Neoplasms
Phosphorylation, glycosylation, and proteolytic activity of the 52-kD estrogen-induced protein secreted by MCF7 cells.
Breast Neoplasms
Pregnancy-associated plasma protein A regulates mitosis and is epigenetically silenced in breast cancer.
Breast Neoplasms
Processing of prolactin by human breast cancer cells in long term tissue culture.
Breast Neoplasms
Prognostic relevance of uPAR-del4/5 and TIMP-3 mRNA expression levels in breast cancer.
Breast Neoplasms
Prognostic significance of immunohistochemical analysis of cathepsin D in low-stage breast cancer.
Breast Neoplasms
Prognostic significance of plasminogen activator inhibitor-1 in breast cancer, with special emphasis on locoregional recurrence-free survival.
Breast Neoplasms
Prognostic significance of the tumor suppressor gene maspin in non-small cell lung cancer.
Breast Neoplasms
Prognostic value of cathepsin D in breast cancer: comparison of immunohistochemical and immunoradiometric detection methods.
Breast Neoplasms
Prostasin serine protease inhibits breast cancer invasiveness and is transcriptionally regulated by promoter DNA methylation.
Breast Neoplasms
Protease Activated Receptors 1 and 2 Correlate Differently with Breast Cancer Aggressiveness Depending on Tumor ER Status.
Breast Neoplasms
Protease Activity and Cell-Free DNA in Blood Plasma of Healthy Donors and Breast Cancer Patients.
Breast Neoplasms
Protease activity of urokinase and tumor progression in a syngeneic mammary cancer model.
Breast Neoplasms
Protease Cargo in Circulating Exosomes of Breast Cancer and Ovarian Cancer Patients
Breast Neoplasms
Protease degradomics: mass spectrometry discovery of protease substrates and the CLIP-CHIP, a dedicated DNA microarray of all human proteases and inhibitors.
Breast Neoplasms
Protease inhibitor antipain reduces nuclear binding of estrogen-receptor complex in MCF-7 breast tumor cells.
Breast Neoplasms
Protease levels in breast, ovary, and other gynecological tumor tissues: prognostic importance in breast cancer.
Breast Neoplasms
Protease Nexin I is a feedback regulator of EGF/PKC/MAPK/EGR1 signaling in breast cancer cells metastasis and stemness.
Breast Neoplasms
Protein C inhibitor inhibits breast cancer cell growth, metastasis and angiogenesis independently of its protease inhibitory activity.
Breast Neoplasms
Protein Z-dependent protease inhibitor (ZPI) is present in loco in human breast cancer tissue.
Breast Neoplasms
Proteolysis of cystatin C by cathepsin D in the breast cancer microenvironment.
Breast Neoplasms
Pulsed Low-Frequency Magnetic Fields Induce Tumor Membrane Disruption and Altered Cell Viability.
Breast Neoplasms
Purification and characterization of a complex containing matriptase and a Kunitz-type serine protease inhibitor from human milk.
Breast Neoplasms
Quality control of cathepsin-D measurement by the EORTC Receptor Study Group.
Breast Neoplasms
Regulating the tumor suppressor gene maspin in breast cancer cells: a potential mechanism for the anticancer properties of tamoxifen.
Breast Neoplasms
Regulation of antitrypsin and antichymotrypsin synthesis by MCF-7 breast cancer cell sublines.
Breast Neoplasms
Regulation of DNA methylation in human breast cancer. Effect on the urokinase-type plasminogen activator gene production and tumor invasion.
Breast Neoplasms
Regulation of motility and protease expression in PKC-mediated induction of MCF-7 breast cancer cell invasiveness.
Breast Neoplasms
Related Endogenous Retrovirus-K Elements Harbor Distinct Protease Active Site Motifs.
Breast Neoplasms
Relationship between cathepsin-D and other prognostic factors in human breast cancer.
Breast Neoplasms
Restricted expression of membrane type 1-matrix metalloproteinase by myofibroblasts adjacent to human breast cancer cells.
Breast Neoplasms
Role of cytoplasmic localization of maspin in promoting cell invasion in breast cancer with aggressive phenotype.
Breast Neoplasms
Screening of single-chain variable fragments against TSP50 from a phage display antibody library and their expression as soluble proteins.
Breast Neoplasms
Secreted and membrane-bound isoforms of protease ADAM9 have opposing effects on breast cancer cell migration.
Breast Neoplasms
Secretory Leukocyte Protease Inhibitor (SLPI) expression downregulates E-cadherin, induces ?-catenin re-localisation and triggers apoptosis-related events in breast cancer cells.
Breast Neoplasms
Seprase promotes rapid tumor growth and increased microvessel density in a mouse model of human breast cancer.
Breast Neoplasms
Seprase, a membrane-bound protease, alleviates the serum growth requirement of human breast cancer cells.
Breast Neoplasms
Serine protease inhibitor TPCK prevents Taxol-induced cell death and blocks c-Raf-1 and Bcl-2 phosphorylation in human breast carcinoma cells.
Breast Neoplasms
Serine protease PRSS23 is upregulated by estrogen receptor ? and associated with proliferation of breast cancer cells.
Breast Neoplasms
Serpin E2 promotes breast cancer metastasis by remodeling the tumor matrix and polarizing tumor associated macrophages.
Breast Neoplasms
Serum insulin-like growth factors, insulin-like growth factor binding proteins, and breast cancer risk in postmenopausal women.
Breast Neoplasms
Serum levels of fetuin-A in patients with coronary artery disease. Corellation with SPET myocardium scintigraphy.
Breast Neoplasms
Serum total and free prostate-specific antigen for breast cancer diagnosis in women.
Breast Neoplasms
Significance of estrogen receptors and cathepsin D tissue detection in gastric adenocarcinoma.
Breast Neoplasms
Significance of the tumor protease Cathepsin D for the biology of breast cancer.
Breast Neoplasms
Single cell multiplexed assay for proteolytic activity using droplet microfluidics.
Breast Neoplasms
Src stimulates fibroblast growth factor receptor-2 shedding by an ADAM15 splice variant linked to breast cancer.
Breast Neoplasms
Stable transfection of the estrogen receptor cDNA into Hela cells induces estrogen responsiveness of endogenous cathepsin D gene but not of cell growth.
Breast Neoplasms
Steroid sequestration and tightly bound oestrogen-protein complexes in human breast tumours and a breast cancer cell line.
Breast Neoplasms
Strong expression association between matriptase and its substrate prostasin in breast cancer.
Breast Neoplasms
Structure and putative signaling mechanism of Protease activated receptor 2 (PAR2) - a promising target for breast cancer.
Breast Neoplasms
Suppression of asparaginyl endopeptidase attenuates breast cancer-induced bone pain through inhibition of neurotrophin receptors.
Breast Neoplasms
Suppression of Asparaginyl Endopeptidase Inhibits Polyomavirus Middle T Antigen-Induced Tumor Formation and Metastasis.
Breast Neoplasms
SUSD2 Proteolytic Cleavage Requires the GDPH Sequence and Inter-Fragment Disulfide Bonds for Surface Presentation of Galectin-1 on Breast Cancer Cells.
Breast Neoplasms
Targeting matriptase in breast cancer abrogates tumour progression via impairment of stromal-epithelial growth factor signalling.
Breast Neoplasms
Targeting metastatic breast cancer with peptide epitopes derived from autocatalytic loop of Prss14/ST14 membrane serine protease and with monoclonal antibodies.
Breast Neoplasms
Targeting serous epithelial ovarian cancer with designer zinc finger transcription factors.
Breast Neoplasms
Targeting the circBMPR2/miR-553/USP4 Axis as a Potent Therapeutic Approach for Breast Cancer.
Breast Neoplasms
Testes-specific protease 50 (TSP50) promotes cell proliferation through the activation of the NF-kappa beta (NF-?B) signaling pathway.
Breast Neoplasms
Testes-specific protease 50 as an independent risk factor for poor prognosis in patients with non-small cell lung cancer.
Breast Neoplasms
Testes-specific protease 50 promotes cell invasion and metastasis by increasing NF-kappaB-dependent matrix metalloproteinase-9 expression.
Breast Neoplasms
The Association of Protease Activated Receptor 1 gene -506 I/D Polymorphism with Disease-Free Survival in Breast Cancer Patients.
Breast Neoplasms
The cell-surface anchored serine protease TMPRSS13 promotes breast cancer progression and resistance to chemotherapy.
Breast Neoplasms
The expression of ubiquitin-specific peptidase 8 and its prognostic role in patients with breast cancer.
Breast Neoplasms
The KLK5 protease suppresses breast cancer by repressing the mevalonate pathway.
Breast Neoplasms
The normal epithelial cell-specific 1 (NES1) gene is up-regulated by steroid hormones in the breast carcinoma cell line BT-474.
Breast Neoplasms
The osteoclast-associated protease cathepsin K is expressed in human breast carcinoma.
Breast Neoplasms
The prognostic-significance of cathepsin-d in breast carcinomas - an immunohistochemical study.
Breast Neoplasms
The serine protease inhibitor protease nexin-1 controls mammary cancer metastasis through LRP-1-mediated MMP-9 expression.
Breast Neoplasms
The urokinase-system in tumor tissue stroma of the breast and breast cancer cell invasion.
Breast Neoplasms
Three-dimensional extracellular matrix culture models of EGFR signalling and drug response.
Breast Neoplasms
Thrombospondin-1 and transforming growth factor beta-1 upregulate plasminogen activator inhibitor type 1 in pancreatic cancer.
Breast Neoplasms
Transcriptional regulation of urokinase (uPA) gene expression in breast cancer cells: role of DNA methylation.
Breast Neoplasms
Transfected cathepsin D stimulates high density cancer cell growth by inactivating secreted growth inhibitors.
Breast Neoplasms
Transforming growth factor beta-1 and amphiregulin act in synergy to increase the production of urokinase-type plasminogen activator in transformed breast epithelial cells.
Breast Neoplasms
TSP50, a possible protease in human testes, is activated in breast cancer epithelial cells.
Breast Neoplasms
Tumor cell invasion is promoted by activation of protease activated receptor-1 in cooperation with the alpha vbeta 5 integrin.
Breast Neoplasms
Tumor-associated proteolytic factors uPA and PAI-1: critical appraisal of their clinical relevance in breast cancer and their integration into decision-support algorithms.
Breast Neoplasms
Tumor-biological factors uPA and PAI-1 as stratification criteria of a multicenter adjuvant chemotherapy trial in node-negative breast cancer.
Breast Neoplasms
Tumour suppression by targeted intravenous non-viral CRISPRa using dendritic polymers.
Breast Neoplasms
Ubiquitin specific protease 21 upregulation in breast cancer promotes cell tumorigenic capability and is associated with the NOD-like receptor signaling pathway.
Breast Neoplasms
Ubiquitin-specific protease 4 inhibits breast cancer cell growth through the upregulation of PDCD4.
Breast Neoplasms
Upstream stimulatory factors mediate estrogen receptor activation of the cathepsin D promoter.
Breast Neoplasms
Urokinase expression in course of benign and malignant mammary lesions: comparison between nodular and healthy tissues.
Breast Neoplasms
Urokinase-plasminogen activator in breast cancer: assay by both catalytic and immunoassay.
Breast Neoplasms
Using a xenograft model of human breast cancer metastasis to find genes associated with clinically aggressive disease.
Breast Neoplasms
Validation of immunolocalization of the urokinase receptor expression in ductal carcinoma in situ of the breast: comparison with detection by non-isotopic in-situ hybridization.
Breast Neoplasms
[Ca(2+)-depend protease (calpain) activity in breast cancer tissue: preliminary report]
Breast Neoplasms
[Expression of cathepsin D in breast cancer and its clinical and histopathological correlations]
Breast Neoplasms
[Mechanism of the overexpression of the cathepsin D gene in breast cancer and consequences in the metastatic process]
Breast Neoplasms
[Proteases by reactive stromal cells in cancer: an attractive therapeutic target]
Bronchiectasis
Neutrophil elastase inhibitors: recent advances in the development of mechanism-based and nonelectrophilic inhibitors.
Bronchiolitis
[Neutrophil activation and protease imbalance in respiratory tract of infants with respiratory syncytial virus bronchiolitis]
Bronchiolitis Obliterans
Increased net gelatinase but not serine protease activity in bronchiolitis obliterans syndrome.
Bronchitis
Generation of Alpha-1 Antitrypsin Knockout and PI*ZZ Ferrets Using Crispr/Cas9. A Genetic Model of Emphysema.
Bronchitis
Localization of low molecular weight protease inhibitor in serous secretory cells of the respiratory tract.
Bronchitis
[Effect of the protease inhibitor aprotinin on pulmonary function and on the inhibitory activity of sputum in patients with chronic obstructive bronchitis]
Bronchitis
[Etiologic significance of hereditary deficiency of proteinase alpha1-inhibitor in the formation of respiratory diseases]
Bronchitis
[Immunological and nonspecific reactivity in patients with infiltrative pulmonary tuberculosis associated with chronic nonspecific lung diseases]
Bronchitis
[Mucous membrane specific protease inhibitors in bronchial mucus in severe chronic obstructive bronchitis and in alpha 1-antitrypsin deficiency syndrome]
Bronchitis
[Status of the protease inhibitor system in patients with dust-induced lung diseases]
Bronchitis
[Therapeutic and prophylactic measures in patients with dust-induced bronchitis complicated by pulmonary emphysema]
Bronchitis, Chronic
Analysis of proteolytic enzymes and their natural inhibitors in serum and bronchial lavage fluid in atopic bronchial asthma, chronic bronchitis and pneumonia.
Bronchitis, Chronic
Neutral and acidic human tracheobronchial mucin. Isolation and characterization of core protein.
Bronchitis, Chronic
Observations of development of resistance to detachment of cultured bovine bronchial epithelial cells in response to protease treatment.
Bronchitis, Chronic
[Characteristics of the biochemical blood indices in patients with pulmonary tuberculosis complicated with chronic bronchitis]
Bronchitis, Chronic
[Proteases and protease inhibitors of possible clinical relevance in COPD of horses]
Bronchitis, Chronic
[Proteolytic activities in bronchoalveolar lavage fluid in pneumonia and chronic bronchitis]
Bronchopulmonary Dysplasia
Oxygen exposure in the newborn guinea pig lung lavage cell populations, chemotactic and elastase response: a possible relationship to neonatal bronchopulmonary dysplasia.
Bronchopulmonary Dysplasia
Protease inhibitors in bronchoalveolar lavage fluid from neonates with special reference to secretory leukocyte protease inhibitor.
Bronchopulmonary Dysplasia
Secretory leukocyte protease inhibitor and lung inflammation in developing bronchopulmonary dysplasia.
Bulbo-Spinal Atrophy, X-Linked
Archaeal proteasomes effectively degrade aggregation-prone proteins and reduce cellular toxicities in mammalian cells.
Burkitt Lymphoma
Down-regulation of proteolytic complexes following EBV activation in BL cells.
Burkitt Lymphoma
Selective Cytotoxicity of Amidinopiperidine Based Compounds Towards Burkitt's Lymphoma Cells Involves Proteasome Inhibition.
Burkitt Lymphoma
Severe osteoporosis and multiple fractures in an AIDS patient treated with short-term steroids for lymphoma: a need for guidelines.
Burkitt Lymphoma
Survival in HIV-infected patients with lymphoma according to the choice of antiretroviral treatment: an observational multicentre study.
Bursitis
Adhesive capsulitis of shoulder and treatment with protease inhibitors in patients with human immunodeficiency virus infection: report of 8 cases.
Bursitis
Adhesive capsulitis of the shoulder in human immunodeficiency virus-positive patients during highly active antiretroviral therapy.
Bursitis
Adhesive capsulitis of the shoulder induced by protease inhibitor therapy. Three new cases.
Bursitis
Bilateral frozen shoulder associated with a three-drug regimen including a protease inhibitor in a patient with human immunodeficiency virus infection to the editor.
Bursitis
Septic Bursitis, a Potential Complication of Protease Inhibitor Use in Hepatitis C Virus.
Byssinosis
The size-distribution and protease content airborne particles in textile mill cardrooms.
Caliciviridae Infections
The enterovirus protease inhibitor rupintrivir exerts cross-genotypic anti-norovirus activity and clears cells from the norovirus replicon.
calpain 8 deficiency
Expanding members and roles of the calpain superfamily and their genetically modified animals.
calpain-3 deficiency
CAPN3-mediated processing of C-terminal titin replaced by pathological cleavage in titinopathy.
calpain-3 deficiency
Interactions with M-band titin and calpain 3 link myospryn (CMYA5) to tibial and limb-girdle muscular dystrophies.
Campylobacter Infections
Peptidase PepP is a novel virulence factor of Campylobacter jejuni contributing to murine campylobacteriosis.
Campylobacter Infections
Protease Activity of Campylobacter jejuni HtrA Modulates Distinct Intestinal and Systemic Immune Responses in Infected Secondary Abiotic IL-10 Deficient Mice.
Candidiasis
Antiretroviral therapy with protease inhibitors has an early, immune reconstitution-independent beneficial effect on Candida virulence and oral candidiasis in human immunodeficiency virus-infected subjects.
Candidiasis
Aspartic protease inhibitors as potential anti-Candida albicans drugs: impacts on fungal biology, virulence and pathogenesis.
Candidiasis
Biochemical analysis and application of molecular display technology on Candida albicans for diagnosing and preventing candidiasis.
Candidiasis
Coccidioidomycosis in human immunodeficiency virus-infected persons in Arizona, 1994-1997: incidence, risk factors, and prevention.
Candidiasis
Contribution of Aspartic Proteases in Candida Virulence. Protease Inhibitors against Candida Infections.
Candidiasis
Evaluation of efficacy, pharmacokinetics and tolerability of peptidomimetic aspartic proteinase inhibitors as cream formulation in experimental vaginal candidiasis.
Candidiasis
Frequency of oropharyngeal candidiasis in HIV-infected patients on protease inhibitor therapy.
Candidiasis
HIV-Protease inhibitors reduce cell adherence of Candida albicans strains by inhibition of yeast secreted aspartic proteases.
Candidiasis
Increased susceptibility to lethal Candida infections in burned mice preinfected with Pseudomonas aeruginosa or pretreated with proteolytic enzymes.
Candidiasis
Oropharyngeal candidiasis in HIV(+) patients may influence the selection of HIV-1 protease variants.
Candidiasis
Oropharyngeal candidiasis in HIV-infected patients under treatment with protease inhibitors.
Candidiasis
Protease and phospholipase activities of Candida spp. isolated from cutaneous candidiasis.
Candidiasis
Reduction in oropharyngeal candidiasis following introduction of protease inhibitors.
Candidiasis, Oral
Antiretroviral therapy with protease inhibitors has an early, immune reconstitution-independent beneficial effect on Candida virulence and oral candidiasis in human immunodeficiency virus-infected subjects.
Candidiasis, Oral
Basement membrane protein and matrix metalloproteinase deregulation in engineered human oral mucosa following infection with Candida albicans.
Candidiasis, Oral
Oral candidiasis in HIV+ patients under treatment with protease inhibitors.
Candidiasis, Oral
Salivary secretory leukocyte protease inhibitor and oral candidiasis in human immunodeficiency virus type 1-infected persons.
Candidiasis, Oral
Withdrawal of fluconazole suppressive therapy for thrush in patients responding to combination antiviral therapy including protease inhibitors.
Carcinogenesis
A growth-regulated protease activity that is inhibited by the anticarcinogenic Bowman-Birk protease inhibitor.
Carcinogenesis
A proteolytic activity in a human breast cancer cell line which is inhibited by the anticarcinogenic Bowman-Birk protease inhibitor.
Carcinogenesis
A serine protease activity in C3H/10T1/2 cells that is inhibited by anticarcinogenic protease inhibitors.
Carcinogenesis
A simple procedure for isolating microgram quantities of biologically active bikunin from human urine.
Carcinogenesis
ADAM-12 as a Diagnostic Marker for the Proliferation, Migration and Invasion in Patients with Small Cell Lung Cancer.
Carcinogenesis
Alantolactone induces cell apoptosis partially through down-regulation of testes-specific protease 50 expression.
Carcinogenesis
Antisense RNA-mediated deficiency of the calpain protease, nCL-4, in NIH3T3 cells is associated with neoplastic transformation and tumorigenesis.
Carcinogenesis
API2-MALT1 oncoprotein promotes lymphomagenesis via unique program of substrate ubiquitination and proteolysis.
Carcinogenesis
Assessing the Influence of a Protease in Cell Migration Using the Barrier-Migration Assay.
Carcinogenesis
Association and clinical implication of the USP10 and MSH2 proteins in non-small cell lung cancer.
Carcinogenesis
ATP-Dependent Lon Protease Contributes to Helicobacter pylori-Induced Gastric Carcinogenesis.
Carcinogenesis
ATP-dependent Lon protease controls tumor bioenergetics by reprogramming mitochondrial activity.
Carcinogenesis
Atypical mechanism of NF-?B activation by TRE17/ubiquitin-specific protease 6 (USP6) oncogene and its requirement in tumorigenesis.
Carcinogenesis
Author Correction: The role of sentrin-specific protease 2 substrate recognition in TGF-?-induced tumorigenesis.
Carcinogenesis
Biochemical characterization of human tissue kallikrein 15 and examination of its potential role in cancer.
Carcinogenesis
Bowman-Birk inhibitor abates proteasome function and suppresses the proliferation of MCF7 breast cancer cells through accumulation of MAP kinase phosphatase-1.
Carcinogenesis
c-Met-induced epithelial carcinogenesis is initiated by the serine protease matriptase.
Carcinogenesis
Candidate single nucleotide polymorphism markers for arsenic responsiveness of protein targets.
Carcinogenesis
Cardamonin inhibited cell viability and tumorigenesis partially through blockade of testes-specific protease 50-mediated nuclear factor-kappaB signaling pathway activation.
Carcinogenesis
Caspase-14 suppresses GCM1 acetylation and inhibits placental cell differentiation.
Carcinogenesis
Cathepsin B in the growth of colorectal cancer: suppressive effect of leupeptin on the growth of DMH-induced rat colon neoplasm.
Carcinogenesis
Cathepsin cysteine proteases are effectors of invasive growth and angiogenesis during multistage tumorigenesis.
Carcinogenesis
Change of polyamine content in mouse skin by leupeptin, a protease inhibitor, during early stage of tumorigenesis.
Carcinogenesis
Chemical Modulation of Human Mitochondrial ClpP: Potential Application in Cancer Therapeutics.
Carcinogenesis
Chemoprevention of rat prostate carcinogenesis by soy isoflavones and by Bowman-Birk inhibitor.
Carcinogenesis
Chromosomal events in carcinogenic initiation and promotion: implications for carcinogenicity testing and cancer prevention strategies.
Carcinogenesis
Confluence switch signaling regulates ECM composition and plasmin proteolytic cascade in keratinocytes.
Carcinogenesis
Crystallization and preliminary X-ray crystallographic studies on a Kunitz-type potato serine protease inhibitor.
Carcinogenesis
Deletion of cathepsin H perturbs angiogenic switching, vascularization and growth of tumors in a mouse model of pancreatic islet cell cancer.
Carcinogenesis
Design, Synthesis, and Testing of Potent, Selective Hepsin Inhibitors via Application of an Automated Closed-Loop Optimization Platform.
Carcinogenesis
Deubiquitinase OTUD6A promotes proliferation of cancer cells via regulating Drp1 stability and mitochondrial fission.
Carcinogenesis
Deubiquitylation and stabilization of Notch1 intracellular domain by ubiquitin-specific protease 8 enhance tumorigenesis in breast cancer.
Carcinogenesis
Diagnostic potential in prostate cancer of a panel of urinary molecular tumor markers.
Carcinogenesis
DNA-dependent protease activity of human Spartan facilitates replication of DNA-protein crosslink-containing DNA.
Carcinogenesis
Downregulation of ER60 Protease Inhibits Cellular Proliferation by Inducing G1/S Arrest in Breast Cancer Cells In Vitro.
Carcinogenesis
Downregulation of ubiquitin-specific protease 14 (USP14) inhibits breast cancer cell proliferation and metastasis, but promotes apoptosis.
Carcinogenesis
Effect of biochanin-a or testosterone on liver-tumors induced by a combined treatment of den and fission neutron in bcf1 mice.
Carcinogenesis
Effect of the synthetic protease inhibitor [N,N-dimethylcarbamoyl-methyl 4-(4-guanidinobenzoyloxy)-phenylacetate] methanesulfate on carcinogenesis by 3-methylcholanthrene in mouse skin.
Carcinogenesis
Effects of protease inhibitors on c-myc expression in normal and transformed C3H 10T1/2 cell lines.
Carcinogenesis
Effects of protease inhibitors on levels of proteolytic activity in normal and premalignant cells and tissues.
Carcinogenesis
Effects of spermine-conjugated Bowman-Birk inhibitor (spermine-BBI) on carcinogenesis and cholesterol biosynthesis in mice.
Carcinogenesis
Effects of the protease inhibitor antipain on cell malignant transformation.
Carcinogenesis
Effects of various preparations of dietary protease inhibitors on oral carcinogenesis in hamsters induced by DMBA.
Carcinogenesis
Emerging role of ubiquitin-specific protease 14 in oncogenesis and development of tumor: Therapeutic implication.
Carcinogenesis
Expression of ADAM9 in CIN3 lesions and squamous cell carcinomas of the cervix.
Carcinogenesis
Expression of USP22 and Survivin is an indicator of malignant behavior in hepatocellular carcinoma.
Carcinogenesis
Fibroblast activation protein (FAP) is upregulated in myelomatous bone and supports myeloma cell survival.
Carcinogenesis
Hepatocyte growth factor activator inhibitor type 1 (Hai-1/Spint1) is a suppressor of intestinal tumorigenesis.
Carcinogenesis
Hepatocyte growth factor activator inhibitor-1 (HAI-1) is essential for the integrity of basement membranes in the developing placental labyrinth.
Carcinogenesis
Human fibroblasts contain a proteolytic activity which is inhibited by the Bowman-Birk protease inhibitor.
Carcinogenesis
Hypermethylation of the 5' CpG island of the gene encoding the serine protease Testisin promotes its loss in testicular tumorigenesis.
Carcinogenesis
Identification of inhibitors using a cell-based assay for monitoring Golgi-resident protease activity.
Carcinogenesis
IGFBP-2 expression in a human cell line is associated with increased IGFBP-3 proteolysis, decreased IGFBP-1 expression and increased tumorigenicity.
Carcinogenesis
IL-6 promotes malignant growth of skin SCCs by regulating a network of autocrine and paracrine cytokines.
Carcinogenesis
Imbalance of the reciprocally inhibitory loop between the ubiquitin-specific protease USP43 and EGFR/PI3K/AKT drives breast carcinogenesis.
Carcinogenesis
Impact of Protease Inhibitors on HIV-Associated Kaposi Sarcoma Incidence: A Systematic Review.
Carcinogenesis
In vitro digestibility of the cancer-preventive soy peptides lunasin and BBI.
Carcinogenesis
Increase in the nuclear localization of PTEN by the Toxoplasma GRA16 protein and subsequent induction of p53-dependent apoptosis and anticancer effect.
Carcinogenesis
Increased expression of ubiquitin-specific protease 22 can promote cancer progression and predict therapy failure in human colorectal cancer.
Carcinogenesis
Increased expression of USP22 is associated with disease progression and patient prognosis of salivary duct carcinoma.
Carcinogenesis
Induction of a novel Ca2+-dependent protease in preneoplastic and neoplastic liver tissues during rat liver carcinogenesis.
Carcinogenesis
Induction of a novel Ca2+-dependent serine protease in rat liver treated with various promoters of liver carcinogenesis.
Carcinogenesis
Influence of HPV16 E2 and its localisation on the expression of matrix metalloproteinase-9.
Carcinogenesis
Inhibition of 7,12-dimethylbenz[alpha]anthracene-induced mammary tumorigenesis in rats by a synthetic protease inhibitor, N,N-dimethylamino-(p-(p'-guanidinobenzoyloxy)) benzilcarbonyloxyglycolate.
Carcinogenesis
Inhibition of benzopyrene-induced forestomach tumors by field bean protease inhibitor(s).
Carcinogenesis
Inhibition of carcinogen-induced chromosomal aberrations by an anticarcinogenic protease inhibitor.
Carcinogenesis
Inhibition of N-nitrosomethylbenzylamine-induced esophageal neoplasms by the Bowman-Birk protease inhibitor.
Carcinogenesis
Inhibition of tumorigenesis in mouse skin by leupeptin, a protease inhibitor from Actinomycetes.
Carcinogenesis
Insights into the regulation of the matriptase-prostasin proteolytic system.
Carcinogenesis
Internalisation of the Bowman-Birk protease inhibitor by intestinal epithelial cells.
Carcinogenesis
Intestinal epithelial cells contain a high molecular weight protease subject to inhibition by anticarcinogenic protease inhibitors.
Carcinogenesis
Intracellular localization of the tumor suppressor HtrA1/Prss11 and its association with HPV16 E6 and E7 proteins.
Carcinogenesis
Isolation of Bowman-Birk-Inhibitor from soybean extracts using novel peptide probes and high gradient magnetic separation
Carcinogenesis
Isolation of Bowman-Birk-Inhibitor from soybean extracts using novel peptide probes and high gradient magnetic separation.
Carcinogenesis
Kallikrein 6 protease advances colon tumorigenesis via induction of the high mobility group A2 protein.
Carcinogenesis
Keratinocyte-specific onset of serine protease BSSP expression in experimental carcinogenesis.
Carcinogenesis
Knock-down of USP22 by small interfering RNA interference inhibits HepG2 cell proliferation and induces cell cycle arrest.
Carcinogenesis
Knockdown of ubiquitin-specific protease 14 (USP14) inhibits the proliferation and tumorigenesis in esophageal squamous cell carcinoma cells.
Carcinogenesis
Local activation of mammalian separase in interphase promotes double-strand break repair and prevents oncogenic transformation.
Carcinogenesis
Lon protease: A key enzyme controlling mitochondrial bioenergetics in cancer.
Carcinogenesis
Long-term feeding of field bean protein containing protease inhibitors suppresses virus-induced mammary tumors in mice.
Carcinogenesis
LonP1 Differently Modulates Mitochondrial Function and Bioenergetics of Primary Versus Metastatic Colon Cancer Cells.
Carcinogenesis
Matriptase activation and shedding through PDGF-D-mediated extracellular acidosis.
Carcinogenesis
Molecular cloning and characterization of a novel esophageal cancer related gene.
Carcinogenesis
Molecular cloning of fibroblast activation protein alpha, a member of the serine protease family selectively expressed in stromal fibroblasts of epithelial cancers.
Carcinogenesis
Molecular insights into substrate specificity of prostate specific antigen through structural modeling.
Carcinogenesis
Molecular-dynamics-simulation-driven design of a protease-responsive probe for in-vivo tumor imaging.
Carcinogenesis
Mucin 16 and kallikrein 13 as potential prognostic factors in colon cancer: Results of an oncological 92-multiplex immunoassay.
Carcinogenesis
Myoepithelial cell-specific expression of stefin A as a suppressor of early breast cancer invasion.
Carcinogenesis
Oncogenic Ras Disrupts Epithelial Integrity by Activating the Transmembrane Serine Protease Hepsin.
Carcinogenesis
OTUB1-mediated deubiquitination of FOXM1 up-regulates ECT-2 to promote tumor progression in renal cell carcinoma.
Carcinogenesis
OTUB2 Promotes Homologous Recombination Repair Through Stimulating Rad51 Expression in Endometrial Cancer.
Carcinogenesis
Overexpression of ubiquitin-specific protease 22 predicts poor survival in patients with early-stage non-small cell lung cancer.
Carcinogenesis
Peptide substrate profiling defines fibroblast activation protein as an endopeptidase of strict Gly(2)-Pro(1)-cleaving specificity.
Carcinogenesis
Piperine treatment suppresses Helicobacter pylori toxin entry in to gastric epithelium and minimizes ?-catenin mediated oncogenesis and IL-8 secretion in vitro.
Carcinogenesis
Plasminogen activator synthesis accompanying chemical carcinogen-induced in vitro transformation of Syrian hamster and guinea-pig fetal cells.
Carcinogenesis
Pleiotropic functions of the tumor- and metastasis-suppressing matrix metalloproteinase-8 in mammary cancer in MMTV-PyMT transgenic mice.
Carcinogenesis
Preventive effect of soybean resistant proteins against experimental tumorigenesis in rat colon.
Carcinogenesis
Protease inhibitor suppression of colon and anal gland carcinogenesis induced by dimethylhydrazine.
Carcinogenesis
Protease inhibitors suppress fibrinolytic activity of herpesvirus-transformed cells.
Carcinogenesis
Radioprotection of normal tissue to improve radiotherapy: the effect of the Bowman Birk protease inhibitor.
Carcinogenesis
RCE1 deficiency enhances invasion via the promotion of epithelial-mesenchymal transition and predicts poor prognosis in hepatocellular carcinoma.
Carcinogenesis
Reduced mammary tumor progression in a transgenic mouse model fed an isoflavone-poor soy protein concentrate.
Carcinogenesis
RNA interference-mediated USP22 gene silencing promotes human brain glioma apoptosis and induces cell cycle arrest.
Carcinogenesis
Role of cytoplasmic localization of maspin in promoting cell invasion in breast cancer with aggressive phenotype.
Carcinogenesis
Secretory leukocyte protease inhibitor modulates urethane-induced lung carcinogenesis.
Carcinogenesis
SENP1-mediated deSUMOylation of USP28 regulated HIF-1? accumulation and activation during hypoxia response.
Carcinogenesis
Serine Protease Inhibitor Kazal Type 1 (SPINK1) Promotes Proliferation of Colorectal Cancer Through the Epidermal Growth Factor as a Prognostic Marker.
Carcinogenesis
Serine protease inhibitor kazal-type 6 inhibits tumorigenesis of human hepatocellular carcinoma cells via its extracellular action.
Carcinogenesis
Structure of the catalytic domain of the human mitochondrial Lon protease: proposed relation of oligomer formation and activity.
Carcinogenesis
Study of post-natal effect of chemopreventive agents on ethylnitrosourea-induced transplacental carcinogenesis in rats. III. Inhibitory action of indomethacin, voltaren, theophylline and epsilon-aminocaproic acid.
Carcinogenesis
Sucralose Promotes Colitis-Associated Colorectal Cancer Risk in a Murine Model Along With Changes in Microbiota.
Carcinogenesis
Suppression of 3-methylcholanthrene-induced cellular transformation by timed administration of the Bowman-Birk protease inhibitor.
Carcinogenesis
Suppression of carcinogenesis in the intestines of min mice by the soybean-derived Bowman-Birk inhibitor.
Carcinogenesis
Suppression of dimethylhydrazine-induced carcinogenesis in mice by dietary addition of the Bowman-Birk protease inhibitor.
Carcinogenesis
TASP1 mutation in a female with craniofacial anomalies, anterior segment dysgenesis, congenital immunodeficiency and macrocytic anemia.
Carcinogenesis
TCDD-inducible plasminogen activator inhibitor type 2 (PAI-2) in human hepatocytes, HepG2 and monocytic U937 cells.
Carcinogenesis
Testes-specific protease 50 promotes cell invasion and metastasis by increasing NF-kappaB-dependent matrix metalloproteinase-9 expression.
Carcinogenesis
The ADAM17 Protease Promotes Tobacco Smoke Carcinogen-induced Lung Tumourigenesis.
Carcinogenesis
The beneficial effects of dietary restriction: reduced oxidative damage and enhanced apoptosis.
Carcinogenesis
The catalytic triad of testes-specific protease 50 (TSP50) is essential for its function in cell proliferation.
Carcinogenesis
The deubiquitinase USP34 stabilizes SOX2 and induces cell survival and drug resistance in laryngeal squamous cell carcinoma.
Carcinogenesis
The dual protease inhibitor lopinavir/ritonavir (LPV/r) exerts genotoxic stress on lung cells.
Carcinogenesis
The effect of essential fatty acids on growth and urokinase-type plasminogen activator production in human prostate DU-145 cells.
Carcinogenesis
The effect of gamma-linolenic acid and eicosapentaenoic acid on urokinase activity.
Carcinogenesis
The field bean protease inhibitor can effectively suppress 7,12-dimethylbenz[a]anthracene-induced skin tumorigenesis in mice.
Carcinogenesis
The interaction of the potato-derived chymotrypsin inhibitor with C3H/10T1/2 cells.
Carcinogenesis
The molecular biology of colorectal cancer development and the associated genetic events.
Carcinogenesis
The role of sentrin-specific protease 2 substrate recognition in TGF-?-induced tumorigenesis.
Carcinogenesis
The role of the LB structural loop and its interactions with the PDZ domain of the human HtrA3 protease.
Carcinogenesis
The serine protease inhibitor serpinE2 is a novel target of ERK signaling involved in human colorectal tumorigenesis.
Carcinogenesis
Thrombin induces tumor invasion through the induction and association of matrix metalloproteinase-9 and beta1-integrin on the cell surface.
Carcinogenesis
TMEM79/MATTRIN defines a pathway for Frizzled regulation and is required for Xenopus embryogenesis.
Carcinogenesis
TMPRSS2, a Serine Protease Expressed in the Prostate on the Apical Surface of Luminal Epithelial Cells and Released into Semen in Prostasomes, Is Misregulated in Prostate Cancer Cells.
Carcinogenesis
TSP50 Depends on Its Threonine Protease Activity and Its Interactions with TNF-?-Induced NF-?B for Its Role in Human Cervical Tumorigenesis.
Carcinogenesis
TSP50 promotes the Warburg effect and hepatocyte proliferation via regulating PKM2 acetylation.
Carcinogenesis
Tumor suppressor PRSS8 targets Sphk1/S1P/Stat3/Akt signaling in colorectal cancer.
Carcinogenesis
Ubiquitin Specific Protease 26 (USP26) expression analysis in human testicular and extragonadal tissues indicates diverse action of USP26 in cell differentiation and tumorigenesis.
Carcinogenesis
Ubiquitin Specific Protease 29 Functions as an Oncogene Promoting Tumorigenesis in Colorectal Carcinoma.
Carcinogenesis
Ubiquitin-speci?c protease 4 promotes metastasis of hepatocellular carcinoma by increasing TGF-? signaling-induced epithelial-mesenchymal transition.
Carcinogenesis
Ubiquitin-specific protease 14 (USP14) promotes proliferation and metastasis in pancreatic ductal adenocarcinoma.
Carcinogenesis
Ubiquitin-specific protease 14 is a new therapeutic target for the treatment of diseases.
Carcinogenesis
Ubiquitin-specific protease 14 regulates cell proliferation and apoptosis in oral squamous cell carcinoma.
Carcinogenesis
Ubiquitin-specific protease 22: a novel molecular biomarker in cervical cancer prognosis and therapeutics.
Carcinogenesis
Ubiquitin-specific protease 22: a novel molecular biomarker in glioma prognosis and therapeutics.
Carcinogenesis
Ubiquitin-Specific Protease 4-Mediated Deubiquitination and Stabilization of PRL-3 Is Required for Potentiating Colorectal Oncogenesis.
Carcinogenesis
USP22 acts as an oncogene by the activation of BMI-1-mediated INK4a/ARF pathway and Akt pathway.
Carcinogenesis
USP22 transcriptional activity is negatively regulated by the histone deacetylase inhibitor trichostatin A.
Carcinogenesis
USP28 Deficiency Promotes Breast and Liver Carcinogenesis as well as Tumor Angiogenesis in a HIF-independent Manner.
Carcinogenesis
USP4 promotes invasion of breast cancer cells via Relaxin/TGF-?1/Smad2/MMP-9 signal.
Carcinogenesis
Usp5 functions as an oncogene for stimulating tumorigenesis in hepatocellular carcinoma.
Carcinogenesis
USP5 promotes tumorigenesis and progression of pancreatic cancer by stabilizing FoxM1 protein.
Carcinogenesis
[Effect of synthetic protease inhibitor on the oncogenesis of pancreatic cancer in hamsters: study on pancreatic endocrine cells and free radicals]
Carcinogenesis
[Histone specific proteinase and DNase activity of spleen lymphocyte nuclei during oncogenesis and under the effect of hydrobromide-5-(5',6' benzocoumaroyl-3')-methylaminouracil]
Carcinogenesis
[Protease inhibitors as anticancer chemotherapy--experimental and clinical studies]
Carcinoid Tumor
Circulation of a fragment of haemoglobin alpha-chain during a pentagastrin-induced flush in patients with metastatic carcinoid tumours.
Carcinoma
A cytosol protease from the estrogen-resistant C3H mammary carcinoma increases the affinity of the estrogen receptor for DNA in vitro.
Carcinoma
A novel peptide-based electrochemical biosensor for the determination of a metastasis-linked protease in pancreatic cancer cells.
Carcinoma
A Novel Tumor Suppressor SPINK5 Serves as an Independent Prognostic Predictor for Patients with Head and Neck Squamous Cell Carcinoma.
Carcinoma
A potentially novel peptidase, resembling but distinct from neutrophil elastase, produced by carcinoma cells.
Carcinoma
A role for membrane-type serine protease (MT-SP1) in intestinal epithelial turnover.
Carcinoma
A serine protease-inhibitory benzamidine derivative inhibits the growth of human colon carcinoma cells.
Carcinoma
Activation of actin-cleavable interleukin 1beta-converting enzyme (ICE) family protease CPP-32 during chemotherapeutic agent-induced apoptosis in ovarian carcinoma cells.
Carcinoma
Adhesion and protease activity in cell lines from human salivary gland tumors are regulated by the laminin-derived peptide AG73, syndecan-1 and beta1 integrin.
Carcinoma
Alpha 1-antitrypsin, alpha 1-antichymotrypsin, and alpha 2-macroglobulin in human gastric carcinomas: a retrospective immunohistochemical study.
Carcinoma
alpha2-Macroglobulin is mainly produced by cancer cells and not by hepatocytes in rats with colon carcinoma metastases in liver.
Carcinoma
An immunohistochemical assessment of cathepsin D in gastric carcinoma: its impact on clinical prognosis.
Carcinoma
Antitumor potential of SLPI promoter controlled recombinant caspase-3 expression in laryngeal carcinoma.
Carcinoma
ASO Author Reflections: Serine Protease 27 is a Novel Prognostic Indicator for Esophageal Squamous Cell Carcinoma with Preoperative Treatment.
Carcinoma
Association and dissociation of a protease and its inhibitor on the surface of lung squamous cell carcinoma cells.
Carcinoma
Association between Time on Protease Inhibitors and the Incidence of Squamous Cell Carcinoma of the Anus among U.S. Male Veterans.
Carcinoma
Association of KLK5 overexpression with invasiveness of urinary bladder carcinoma cells.
Carcinoma
Autocrine induction of invasion and metastasis by tumor-associated trypsin inhibitor in human colon cancer cells.
Carcinoma
Autocrine regulation of cell proliferation by the insulin-like growth factor (IGF) and IGF binding protein-3 protease system in a human prostate carcinoma cell line (PC-3).
Carcinoma
Binding of TGF-beta1 latency-associated peptide (LAP) to alpha(v)beta6 integrin modulates behaviour of squamous carcinoma cells.
Carcinoma
c-Met-induced epithelial carcinogenesis is initiated by the serine protease matriptase.
Carcinoma
Cathepsin D concentration in breast cancer cytosols: correlation with biochemical, histological, and clinical findings.
Carcinoma
Catheter-based in vivo imaging of enzyme activity and gene expression: feasibility study in mice.
Carcinoma
CEBPB knockdown sensitizes nasopharyngeal carcinoma cells to cisplatin by promoting the expression of serine protease inhibitor Kazal-type 5.
Carcinoma
Characterization of monoclonal antibodies directed against squamous cell carcinoma antigens: report of the TD-10 Workshop.
Carcinoma
Characterization of mullerian inhibiting substance binding on cervical carcinoma cells demonstrated by immunocytochemistry.
Carcinoma
Clinical experience with a protease inhibitor [N,N-dimethylcarbamoylmethyl 4-(4-guanidinobenzoyloxy)-phenylacetate] methanesulfate for prevention of recurrence of carcinoma of the mouth and in treatment of terminal carcinoma.
Carcinoma
Clinical validation of combined serological biomarkers for improved hepatocellular carcinoma diagnosis in 961 patients.
Carcinoma
Cloning and expression of a novel hepatitis B virus-binding protein from HepG2 cells.
Carcinoma
Cloning of tumor-associated differentially expressed gene-14, a novel serine protease overexpressed by ovarian carcinoma.
Carcinoma
Combined radiation sensitizing and anti-angiogenic effects of ionizing radiation and the protease inhibitor ritonavir in a head and neck carcinoma model.
Carcinoma
Combined treatment with serine protease inhibitor aprotinin and matrix metalloproteinase inhibitor Batimastat (BB-94) does not prevent invasion of human esophageal and ovarian carcinoma cells in vivo.
Carcinoma
Comparative Analysis of P63, Maspin and Matrix Metalloproteinase 2 Expression in Mucoepidermoid Carcinoma and Adenoid Cystic Carcinoma of Salivary Glands.
Carcinoma
Comparison of tissue kallikrein and kinin receptor expression in gastric ulcers and neoplasms.
Carcinoma
Copy number and expression alterations of miRNAs in the ovarian cancer cell line OVCAR-3: impact on kallikrein 6 protein expression.
Carcinoma
Correlations between cell surface protease activities and abnormalities of occludens junctions in rat bladder carcinoma in vitro.
Carcinoma
CVS-3983, a selective matriptase inhibitor, suppresses the growth of androgen independent prostate tumor xenografts.
Carcinoma
Cystatin D Locates in the Nucleus at Sites of Active Transcription and Modulates Gene and Protein Expression.
Carcinoma
Decreased H2B monoubiquitination and overexpression of ubiquitin-specific protease enzyme 22 in malignant colon carcinoma.
Carcinoma
Delineation of matriptase protein expression by enzymatic gene trapping suggests diverging roles in barrier function, hair formation, and squamous cell carcinogenesis.
Carcinoma
Delivery of a Proapoptotic Peptide to EGFR-Positive Cancer Cells by a Cyclic Peptide Mimicking the Dimerization Arm Structure of EGFR.
Carcinoma
Detection of human glandular kallikrein, hK2, as its precursor form and in complex with protease inhibitors in prostate carcinoma serum.
Carcinoma
Detection of oral squamous cell carcinoma metastasis with cathepsin D: An immunohistochemical approach.
Carcinoma
Development of albumin-binding doxorubicin prodrugs that are cleaved by prostate-specific antigen.
Carcinoma
Differential competitive inhibition of a cell surface protease on normal epithelial cells and carcinoma cells of the colon.
Carcinoma
Differential effects of periopathogens on host protease inhibitors SLPI, elafin, SCCA1, and SCCA2.
Carcinoma
Differential expression of a novel serine protease homologue in squamous cell carcinoma of the head and neck.
Carcinoma
Differential expression of protease activated receptor 1 (Par1) and pY397FAK in benign and malignant human ovarian tissue samples.
Carcinoma
Differential expression of protease activity in serum samples of prostate carcinoma patients with metastases.
Carcinoma
Differential response of premalignant epithelial cell classes to phorbol ester tumor promoters and to deoxycholic acid.
Carcinoma
Downregulation of ubiquitin-specific protease 2 possesses prognostic and diagnostic value and promotes the clear cell renal cell carcinoma progression.
Carcinoma
Effect of a protease inhibitor [N,N-dimethylcarbamoylmethyl 4-(4-guanidinobenzoyloxy)-phenylacetate] methanesulfate on the growth of mouse skin carcinoma in the rapid growing stage.
Carcinoma
Effect of oral administration of protease inhibitor [N,N-dimethylcarbamoylmethyl 4-(4-guanidinobenzoyloxy)-phenylacetate] methanesulfate on the growth of 3-methylcholanthrene-induced carcinoma in mice.
Carcinoma
Effects of Open versus Laparoscopic Nephrectomy Techniques on Oxidative Stress Markers in Patients with Renal Cell Carcinoma.
Carcinoma
Effects of serine protease inhibitor FOY-305 and heparin on the growth of squamous cell carcinoma.
Carcinoma
Efficacy of different proteolytic treatments for the immunohistochemical stain of cytokeratins.
Carcinoma
EGF stimulates Cdc42-dependent translocation of SCC antigen to the plasma membrane.
Carcinoma
Elevated expression of squamous cell carcinoma antigen (SCCA) is associated with human breast carcinoma.
Carcinoma
Endogenous cathepsin D-mediated hydrolysis of insulin-like growth factor-binding proteins in cultured human prostatic carcinoma cells.
Carcinoma
Endogenous receptor-bound urokinase mediates tissue invasion of the human lung carcinoma cell lines A549 and Calu-1.
Carcinoma
Epigenetic silencing of the PRSS3 putative tumor suppressor gene in non-small cell lung cancer.
Carcinoma
Establishment of a new human cancer cell line secreting protease nexin-II/amyloid beta protein precursor derived from squamous-cell carcinoma of lung.
Carcinoma
Estradiol-induced biochemical changes in human neoplastic cells: estradiol-mediated protease.
Carcinoma
Evaluation of matrix metalloproteinase 7 in plasma and pancreatic juice as a biomarker for pancreatic cancer.
Carcinoma
Expression of p63, TTF-1 and Maspin in Non-Small Cell Lung Carcinoma and Their Effect on the Prognosis and Differential Diagnosis.
Carcinoma
Expression of protease activated receptor-2 is reduced in renal cell carcinoma biopsies and cell lines.
Carcinoma
Expression of serine protease matriptase in renal cell carcinoma: correlation of tissue microarray immunohistochemical expression analysis results with clinicopathological parameters.
Carcinoma
Expression of the serine protease DESC1 correlates directly with normal keratinocyte differentiation and inversely with head and neck squamous cell carcinoma progression.
Carcinoma
Expression of the tumor suppressor gene maspin and its significance in intraductal papillary mucinous neoplasms of the pancreas.
Carcinoma
Expression patterns of seprase, a membrane serine protease, in cervical carcinoma and cervical intraepithelial neoplasm.
Carcinoma
Expression Status of Serine Protease 27: A Prognostic Marker for Esophageal Squamous Cell Carcinoma Treated with Preoperative Chemotherapy/Chemoradiotherapy.
Carcinoma
FAP-alpha and uPA show different expression patterns in premalignant and malignant esophageal lesions.
Carcinoma
Fibrin formation induced by tumor procoagulants enhances urokinase activity produced by mammary carcinoma cells.
Carcinoma
Fibroblast activation proteins-? suppress tumor immunity by regulating T cells and tumor-associated macrophages.
Carcinoma
FOXP1 and SPINK1 reflect the risk of cirrhosis progression to HCC with HBV infection.
Carcinoma
Further purification and characterization of acid-stable protease inhibitor from ascites of an ovarian carcinoma patient.
Carcinoma
Genes related to growth and invasiveness are repressed by sodium butyrate in ovarian carcinoma cells.
Carcinoma
Growth differentiation factor-15: a p53- and demethylation-upregulating gene represses cell proliferation, invasion, and tumorigenesis in bladder carcinoma cells.
Carcinoma
Growth-suppressive activities of serine protease inhibitors, FOY-305, ONO-3403 and FO-349 toward human carcinoma cells.
Carcinoma
Hepsin, a cell surface serine protease identified in hepatoma cells, is overexpressed in ovarian cancer.
Carcinoma
High density of tryptase-positive mast cells in patients with renal cell carcinoma on hemodialysis: correlation with expression of stem cell factor and protease activated receptor-2.
Carcinoma
High Expression of Ubiquitin-Specific Protease 8 (USP8) Is Associated with Poor Prognosis in Patients with Cervical Squamous Cell Carcinoma.
Carcinoma
High molecular mass type i.v. collagen-specific metalloprotease from human carcinoma tissue.
Carcinoma
High molecular weight cytokeratin antibody (clone 34betaE12): a sensitive marker for differentiation of high-grade invasive urothelial carcinoma from prostate cancer.
Carcinoma
Human kallikrein 2 (hK2), but not prostate-specific antigen (PSA), rapidly complexes with protease inhibitor 6 (PI-6) released from prostate carcinoma cells.
Carcinoma
Human papillomavirus infection in head and neck cancer: The role of the secretory leukocyte protease inhibitor.
Carcinoma
Identification and characterization of a Kunitz-type protease inhibitor in ascites fluid from patients with ovarian carcinoma.
Carcinoma
Identification of aberrantly regulated genes in diseased skin using the cDNA differential display technique.
Carcinoma
Identification of biomarkers for drug-resistant endometriosis using clinical proteomics.
Carcinoma
Identification of inhibitory scFv antibodies targeting fibroblast activation protein utilizing phage display functional screens.
Carcinoma
Identification of selective and potent inhibitors of fibroblast activation protein and prolyl oligopeptidase.
Carcinoma
Immunoglobulin and enzyme-conjugated dextran polymers enhance u-PAR staining intensity of carcinoma cells in peripheral blood smears.
Carcinoma
Immunohistochemical expression of Ets-related gene-transcriptional factor in adenocarcinoma prostate and its correlation with Gleason score.
Carcinoma
Immunostaining of intermediate filament proteins in paraffin sections. Evaluation of optimal protease treatment to improve the immunoreactivity.
Carcinoma
In vitro anti-cancer activities in Caco-2 and HCT-116 cells of recombinant cystatin C prepared by a Pichia expression system.
Carcinoma
Inhibition of apoptosis in human tumour cells by the tumour-associated serpin, SCC antigen-1.
Carcinoma
Inhibition of epidermal growth factor-induced invasion by dexamethasone and AP-1 decoy in human squamous cell carcinoma cell lines.
Carcinoma
Inhibition of LONP1 Suppresses Pancreatic Cancer Progression Via c-Jun N-Terminal Kinase Pathway-Meditated Epithelial-Mesenchymal Transition.
Carcinoma
Initiation of the extrinsic pathway of blood coagulation: evidence for the tissue factor dependent autoactivation of human coagulation factor VII.
Carcinoma
Integral membrane protease fibroblast activation protein sensitizes fibrosarcoma to chemotherapy and alters cell death mechanisms.
Carcinoma
Isolation of a protease from the cell-free medium of in vitro cultured mammary carcinoma.
Carcinoma
Iterative design of emetine-based prodrug targeting fibroblast activation protein (FAP) and dipeptidyl peptidase IV DPPIV using a tandem enzymatic activation strategy.
Carcinoma
Knockdown of ubiquitin-specific protease 14 (USP14) inhibits the proliferation and tumorigenesis in esophageal squamous cell carcinoma cells.
Carcinoma
Knockdown of Ubiquitin-Specific Protease 53 Enhances the Radiosensitivity of Human Cervical Squamous Cell Carcinoma by Regulating DNA Damage-Binding Protein 2.
Carcinoma
Laminin-1 and SIKVAV a laminin-1-derived peptide, regulate the morphology and protease activity of a human salivary gland adenoid cystic carcinoma cell line.
Carcinoma
Laminin-derived peptide AG73 regulates migration, invasion, and protease activity of human oral squamous cell carcinoma cells through syndecan-1 and beta1 integrin.
Carcinoma
Loss of hepatocyte growth factor activator inhibitor type 1 participates in metastatic spreading of human pancreatic cancer cells in a mouse orthotopic transplantation model.
Carcinoma
Loss of heterozygosity in mammary serine protease inhibitor (maspin) and p53 at chromosome 17 and 18 in oral cavity squamous cell carcinoma.
Carcinoma
Loss of membrane-bound serine protease inhibitor HAI-1 induces oral squamous cell carcinoma cells invasiveness.
Carcinoma
Loss of SPINK1 expression is associated with unfavorable outcomes in urothelial carcinoma of the bladder after radical cystectomy.
Carcinoma
Low levels of urokinase plasminogen activator components in basal cell carcinoma of the skin.
Carcinoma
Mammary serine protease inhibitor and CD138 immunohistochemical expression in ovarian serous and clear cell carcinomas.
Carcinoma
Mammary serine protease inhibitor inhibits epithelial growth factor-induced epithelial-mesenchymal transition of esophageal carcinoma cells.
Carcinoma
Maspin acts at the cell membrane to inhibit invasion and motility of mammary and prostatic cancer cells.
Carcinoma
Maspin is useful in the distinction of pancreatic adenocarcinoma from chronic pancreatitis: a tissue microarray based study.
Carcinoma
Maspin suppresses growth, proliferation and invasion in cutaneous squamous cell carcinoma cells.
Carcinoma
Maspin, p53, p63, and Ki-67 in epithelial lesions of the tongue: from hyperplasia through dysplasia to carcinoma.
Carcinoma
Mast cell chymase is present in uterine cervical carcinoma and it detaches viable and growing cervical squamous carcinoma cells from substratum in vitro.
Carcinoma
Matriptase activates stromelysin (MMP-3) and promotes tumor growth and angiogenesis.
Carcinoma
Matriptase and HAI-1 are expressed by normal and malignant epithelial cells in vitro and in vivo.
Carcinoma
Matriptase is inhibited by extravascular antithrombin in epithelial cells but not in most carcinoma cells.
Carcinoma
Mechanism of apoptotic cell death of human gastric carcinoma cells mediated by transforming growth factor beta.
Carcinoma
Methylation of tumour suppressor genes APAF-1 and DAPK-1 and in vitro effects of demethylating agents in bladder and kidney cancer.
Carcinoma
Microarray analysis of A549 cells infected with rabbitpox virus (RPV): a comparison of wild-type RPV and RPV deleted for the host range gene, SPI-1.
Carcinoma
microRNA-186 Suppresses Cell Proliferation and Metastasis Through Targeting Sentrin Specific Protease 1 in Renal Cell Carcinoma.
Carcinoma
miR-186 promotes tumor growth in cutaneous squamous cell carcinoma by inhibiting apoptotic protease activating factor-1.
Carcinoma
Molecular cloning of proteinase-encoding genes from cancer cells by zymogen assay and direct sequencing.
Carcinoma
mRNA expression and hypermethylation of tumor suppressor genes apoptosis protease activating factor-1 and death-associated protein kinase in oral squamous cell carcinoma.
Carcinoma
Multiple sites of proteolytic cleavage to release soluble forms of hepatocyte growth factor activator inhibitor type 1 from a transmembrane form.
Carcinoma
Narrowing of the region of allelic loss in 21q11-21 in squamous non-small cell lung carcinoma and cloning of a novel ubiquitin-specific protease gene from the deleted segment.
Carcinoma
Neutrophil cathepsin G, but not elastase, induces aggregation of MCF-7 mammary carcinoma cells by a protease activity-dependent cell-oriented mechanism.
Carcinoma
New relationships between prostatic intraepithelial neoplasia and prostatic carcinoma.
Carcinoma
Non-hematopoietic PAR-2 is essential for matriptase-driven pre-malignant progression and potentiation of ras-mediated squamous cell carcinogenesis.
Carcinoma
Nonpolarized secretion of human meprin alpha in colorectal cancer generates an increased proteolytic potential in the stroma.
Carcinoma
Novel forms of squamous cell carcinoma antigen transcripts produced by alternative splicing.
Carcinoma
Nuclear localization of mammary serine protease inhibitor (MASPIN): is its impact on the prognosis in laryngeal carcinoma due to a proapoptotic effect?
Carcinoma
Oncogenic Ras induces inflammatory cytokine production by upregulating the squamous cell carcinoma antigens SerpinB3/B4.
Carcinoma
Overexpression of pregnancy-associated plasma protein-a in ovarian cancer cells promotes tumor growth in vivo.
Carcinoma
Overexpression of protease nexin-1 mRNA and protein in oral squamous cell carcinomas.
Carcinoma
Overexpression of squamous cell carcinoma antigen in idiopathic pulmonary fibrosis: clinicopathological correlations.
Carcinoma
Overexpression of testisin, a serine protease expressed by testicular germ cells, in epithelial ovarian tumor cells.
Carcinoma
PAR-2 promotes cell proliferation, migration, and invasion through activating PI3K/AKT signaling pathway in oral squamous cell carcinoma.
Carcinoma
Paracrine factor and cell-cell contact-mediated induction of protease and c-ets gene expression in malignant keratinocyte/dermal fibroblast cocultures.
Carcinoma
Pericellular activation of hepatocyte growth factor by the transmembrane serine proteases matriptase and hepsin, but not by the membrane-associated protease uPA.
Carcinoma
Photodynamic molecular beacon triggered by fibroblast activation protein on cancer-associated fibroblasts for diagnosis and treatment of epithelial cancers.
Carcinoma
Plasminogen fragmentation and increased production of extracellular matrix-degrading proteinases are associated with serous epithelial ovarian cancer progression.
Carcinoma
Presence of alpha-1-antitrypsin in pancreatic carcinoma. Report of four cases in association with hepatic storage of the protease inhibitor.
Carcinoma
Probing the interaction mechanism of small molecule inhibitors with matriptase based on molecular dynamics simulation and free energy calculations.
Carcinoma
Prointegrin maturation follows rapid trafficking and processing of MT1-MMP in Furin-Negative Colon Carcinoma LoVo Cells.
Carcinoma
Prostate-specific antigen (PSA/hK3): a further player in the field of breast cancer diagnostics?
Carcinoma
Prostatic human kallikrein 2 inactivates and complexes with plasminogen activator inhibitor-1.
Carcinoma
Protease and antiprotease concentrations in serum and vaginal fluid of patients with carcinoma of the cervix.
Carcinoma
Protease inhibitor suppression of colon and anal gland carcinogenesis induced by dimethylhydrazine.
Carcinoma
Protease-mediated fragmentation of p-amidobenzyl ethers: a new strategy for the activation of anticancer prodrugs.
Carcinoma
Proteases and their inhibitors as prognostic factors for high-grade serous ovarian cancer.
Carcinoma
Proteolytic cleavage of glycoprotein B is dispensable for in vitro replication, but required for syncytium formation of pseudorabies virus.
Carcinoma
Purification from human milk of matriptase complexes with secreted serpins: mechanism for inhibition of matriptase other than HAI-1.
Carcinoma
Rapid vessel regression, protease inhibition, and stromal normalization upon short-term vascular endothelial growth factor receptor 2 inhibition in skin carcinoma heterotransplants.
Carcinoma
Rearrangement of squamous cell carcinoma antigen genes--detection of SCCA fusion transcripts.
Carcinoma
Relationship between transmembrane serine protease expression and prognosis of esophageal squamous cell carcinoma.
Carcinoma
Reverse biochemistry: use of macromolecular protease inhibitors to dissect complex biological processes and identify a membrane-type serine protease in epithelial cancer and normal tissue.
Carcinoma
Reverse-zymographic analysis of protease nexin-II/amyloid beta protein precursor of human carcinoma cell lines, with special reference to the grade of differentiation and metastatic phenotype.
Carcinoma
Role of membrane type 1-matrix metalloproteinase and gelatinase A in head and neck squamous cell carcinoma invasion in vitro.
Carcinoma
ROLE OF PLASMINOGEN ACTIVATOR INHIBITOR-1 IN UROKINASE'S PARADOXICAL IN VIVO TUMOR SUPPRESSING OR PROMOTING EFFECTS.
Carcinoma
SCCA2 inhibits TNF-mediated apoptosis in transfected HeLa cells. The reactive centre loop sequence is essential for this function and TNF-induced cathepsin G is a candidate target.
Carcinoma
Scoring of p53, VEGF, Bcl-2 and APAF-1 immunohistochemistry and interobserver reliability in colorectal cancer.
Carcinoma
Secretory leukocyte protease inhibitor (SLPI) expression and tumor invasion in oral squamous cell carcinoma.
Carcinoma
Selective inhibition of NF-?B suppresses bone invasion by oral squamous cell carcinoma in vivo.
Carcinoma
Sentrin/small ubiquitin-like modifier-specific protease 5 protects oral cancer cells from oxidative stress-induced apoptosis.
Carcinoma
Serine protease inhibitor (SERPIN) B1 promotes oral cancer cell motility and is over-expressed in invasive oral squamous cell carcinoma.
Carcinoma
Serine protease inhibitor activity of recombinant squamous cell carcinoma antigen towards chymotrypsin, as demonstrated by sodium dodecyl sulfate-polyacrylamide gel electrophoresis.
Carcinoma
SERPINB11 Expression Is Associated With Prognosis of High-grade Serous and Clear Cell Carcinoma of the Ovary.
Carcinoma
Si113-prodrugs selectively activated by plasmin against hepatocellular and ovarian carcinoma.
Carcinoma
SIKVAV, a laminin alpha1-derived peptide, interacts with integrins and increases protease activity of a human salivary gland adenoid cystic carcinoma cell line through the ERK 1/2 signaling pathway.
Carcinoma
SIKVAV, a Laminin {alpha}1-Derived Peptide, Interacts with Integrins and Increases Protease Activity of a Human Salivary Gland Adenoid Cystic Carcinoma Cell Line through the ERK 1/2 Signaling Pathway.
Carcinoma
SlpE is a calcium-dependent cytotoxic metalloprotease associated with clinical isolates of Serratia marcescens.
Carcinoma
SLPI and AnxA2 expression in neoplasm-free palatine tonsils is associated with smoking habit of individuals.
Carcinoma
SLPI facilitates cell migration by regulating lamellipodia/ruffles and desmosomes, in which Galectin4 plays an important role.
Carcinoma
Soluble Form of the (Pro)Renin Receptor Generated by Intracellular Cleavage by Furin Is Secreted in Plasma.
Carcinoma
Spatial distribution of endogenous tissue protease activity in gastric carcinoma mapped by MALDI mass spectrometry imaging.
Carcinoma
SPI-CI and SPI-6 cooperate in the protection from effector cell-mediated cytotoxicity.
Carcinoma
Squamous cell carcinoma antigen 1 promotes caspase-8-mediated apoptosis in response to endoplasmic reticulum stress while inhibiting necrosis induced by lysosomal injury.
Carcinoma
Squamous cell carcinoma antigen is a new member of the serine protease inhibitors.
Carcinoma
Squamous cell carcinoma antigen-IgM (SCCA-IgM) is associated with interstitial lung disease in systemic sclerosis.
Carcinoma
Stromelysin-3 expression in noninvasive and invasive neoplasms of the urinary bladder.
Carcinoma
Structural Basis of Covalent Inhibitory Mechanism of TMPRSS2-Related Serine Proteases by Camostat.
Carcinoma
Structure of the mouse metalloprotease meprin beta gene (Mep1b): alternative splicing in cancer cells.
Carcinoma
Synthesis and biological evaluation of an albumin-binding prodrug of doxorubicin that is cleaved by prostate-specific antigen (PSA) in a PSA-positive orthotopic prostate carcinoma model (LNCaP).
Carcinoma
T-cell receptor zeta-chain expression on tumor-infiltrating lymphocytes from renal cell carcinoma.
Carcinoma
TADG-12 as an early marker in the development of pancreatic ductal adenocarcinoma (PDAC): Involvement of insulin containing cells.
Carcinoma
Targeted inhibition of cell-surface serine protease Hepsin blocks prostate cancer bone metastasis.
Carcinoma
Tazarotene-Induced Gene 1 (TIG1) Interacts with Serine Protease Inhibitor Kazal-Type 2 (SPINK2) to Inhibit Cellular Invasion of Testicular Carcinoma Cells.
Carcinoma
The alarm anti-protease, secretory leukocyte protease inhibitor, is a proliferation and survival factor for ovarian cancer cells.
Carcinoma
The antileukoprotease secretory leukocyte protease inhibitor (SLPI) and its role in the prevention of HPV-infections in head and neck squamous cell carcinoma.
Carcinoma
The association between protease inhibitors and anal cancer outcomes in veterans living with HIV treated with definitive chemoradiation: a retrospective study.
Carcinoma
The deubiquitinase USP34 stabilizes SOX2 and induces cell survival and drug resistance in laryngeal squamous cell carcinoma.
Carcinoma
The EMT-related transcription factor snail up-regulates FAP? in malignant melanoma cells.
Carcinoma
The Expression of FAP in Hepatocellular Carcinoma Cells is Induced by Hypoxia and Correlates with Poor Clinical Outcomes.
Carcinoma
The increase in tryptase- and chymase-positive mast cells is associated with partial inactivation of chymase and increase in protease inhibitors in basal cell carcinoma.
Carcinoma
The level of secretory leukocyte protease inhibitor is decreased in metastatic head and neck squamous cell carcinoma.
Carcinoma
The mediating role of caspase-3 protease in the intracellular mechanism of genistein-induced apoptosis in human prostatic carcinoma cell lines, DU145 and LNCaP.
Carcinoma
The mRNA coding for the secreted protease transin is expressed more abundantly in malignant than in benign tumors.
Carcinoma
The novel serine protease tumor-associated differentially expressed gene-14 (KLK8/Neuropsin/Ovasin) is highly overexpressed in cervical cancer.
Carcinoma
The novel serine protease tumor-associated differentially expressed gene-15 (matriptase/MT-SP1) is highly overexpressed in cervical carcinoma.
Carcinoma
The Oral Serine Protease Inhibitor WX-671 - First Experience in Patients with Advanced Head and Neck Carcinoma.
Carcinoma
The presence of elafin, SLPI, IL1-RA and STNFalpha RI in head and neck squamous cell carcinomas and their relation to the degree of tumour differentiation.
Carcinoma
The protease activated receptor 1 gene variation IVSn -14A>T is associated with distant metastasis and cancer-specific survival in renal cell carcinoma.
Carcinoma
The ratio of Matriptase/HAI-1 mRNA is higher in colorectal cancer adenomas and carcinomas than corresponding tissue from control individuals.
Carcinoma
The role of interleukin-4 and interleukin-13 in the non-immunologic aspects of asthma pathogenesis.
Carcinoma
The serine protease inhibitor of Kazal-type 9 (SPINK9) is expressed in lichen simplex chronicus, actinic keratosis and squamous cell carcinoma.
Carcinoma
Therapeutic Potential of Medicinal Plant Proteins: Present Status and Future Perspectives.
Carcinoma
Tumor cell adhesion and migration supported by interaction of a receptor-protease complex with its inhibitor.
Carcinoma
Tumor suppressor activity and epigenetic inactivation of hepatocyte growth factor activator inhibitor type 2/SPINT2 in papillary and clear cell renal cell carcinoma.
Carcinoma
Tumor-promoter-enhanced destruction of noninvasive human benign colon tumor cells by cocultivated carcinoma cells.
Carcinoma
Tunicamycin inhibits colon carcinoma growth and aggressiveness via modulation of the ERK-JNK-mediated AKT/mTOR signaling pathway.
Carcinoma
Two-dimensional polyacrylamide gel electrophoresis of the protease SP220K, a renal cell carcinoma marker.
Carcinoma
Ubiquitin-specific protease 14 promotes radio-resistance and suppresses autophagy in oral squamous cell carcinoma.
Carcinoma
Ubiquitin-specific protease 14 regulates cell proliferation and apoptosis in oral squamous cell carcinoma.
Carcinoma
Ubiquitin-specific protease 4 promotes TNF-?-induced apoptosis by deubiquitination of RIP1 in head and neck squamous cell carcinoma.
Carcinoma
Up-regulation of Rho/ROCK signaling in sarcoma cells drives invasion and increased generation of protrusive forces.
Carcinoma
USP22 nuclear expression is significantly associated with progression and unfavorable clinical outcome in human esophageal squamous cell carcinoma.
Carcinoma
Verapamil inhibits tumor protease production, local invasion and metastasis development in murine carcinoma cells.
Carcinoma
Viola Yedoensis Suppresses Cell Invasion by Targeting the Protease and NF-?B Activities in A549 and Lewis Lung Carcinoma Cells.
Carcinoma
Zebrafish modeling reveals that SPINT1 regulates the aggressiveness of skin cutaneous melanoma and its crosstalk with tumor immune microenvironment.
Carcinoma
[Analysis of the Squamous Cell Carcinoma Antigen (SCCA) Which Has a Significant Difference in Values between CLIA and FEIA--Case Report of Extra Glycosylation in SCCA].
Carcinoma
[Demonstration of an epidermal SH-protease inhibitor in normal epithelium and in some human neoplasms--an immunological study (author's transl)]
Carcinoma
[Effect of the protease inhibitor kontrikal on the transplantability and growth of a solid Ehrlich carcinoma in mice]
Carcinoma
[Expression of human epidermal growth factor and DNA ploidy pattern in gastric carcinoma]
Carcinoma
[Inhibitory effect and the mechanism of Astragalus polysaccharide combined with cisplatin on growth of inplanted Lewis lung carcinoma in mice].
Carcinoma
[Relationship between gastric carcinoma and enzyme spectrum activity in gastric mucosal intestinal metaplasia]
Carcinoma, Adenoid Cystic
Adhesion and protease activity in cell lines from human salivary gland tumors are regulated by the laminin-derived peptide AG73, syndecan-1 and beta1 integrin.
Carcinoma, Adenoid Cystic
Comparative Analysis of P63, Maspin and Matrix Metalloproteinase 2 Expression in Mucoepidermoid Carcinoma and Adenoid Cystic Carcinoma of Salivary Glands.
Carcinoma, Adenoid Cystic
Laminin-1 and SIKVAV a laminin-1-derived peptide, regulate the morphology and protease activity of a human salivary gland adenoid cystic carcinoma cell line.
Carcinoma, Adenoid Cystic
SIKVAV, a laminin alpha1-derived peptide, interacts with integrins and increases protease activity of a human salivary gland adenoid cystic carcinoma cell line through the ERK 1/2 signaling pathway.
Carcinoma, Adenoid Cystic
SIKVAV, a Laminin {alpha}1-Derived Peptide, Interacts with Integrins and Increases Protease Activity of a Human Salivary Gland Adenoid Cystic Carcinoma Cell Line through the ERK 1/2 Signaling Pathway.
Carcinoma, Basal Cell
Differential protease expression by cutaneous squamous and basal cell carcinomas.
Carcinoma, Basal Cell
The increase in tryptase- and chymase-positive mast cells is associated with partial inactivation of chymase and increase in protease inhibitors in basal cell carcinoma.
Carcinoma, Ductal
Expression of the serine protease, matriptase, in breast ductal carcinoma of Chinese women: correlation with clinicopathological parameters.
Carcinoma, Ductal
Seprase, a membrane-bound protease, alleviates the serum growth requirement of human breast cancer cells.
Carcinoma, Ductal
Seprase, a membrane-bound protease, is overexpressed by invasive ductal carcinoma cells of human breast cancers.
Carcinoma, Ductal
The cell-surface anchored serine protease TMPRSS13 promotes breast cancer progression and resistance to chemotherapy.
Carcinoma, Ehrlich Tumor
A unique trypsin-like protease associated with plasma membranes of rat liver.
Carcinoma, Ehrlich Tumor
Effect of protease and protease inhibitors on the adhesion of Ehrlich ascites tumour cells to plastic.
Carcinoma, Ehrlich Tumor
Evidence for the presence of a trypsin inhibitor within rabbit and mouse tumour cells.
Carcinoma, Ehrlich Tumor
Inhibition properties of Sepharose-bound trypsin and a protease on the surface of Ehrlich ascites tumour cells.
Carcinoma, Ehrlich Tumor
Phosphorylation of the beta subunit of Na+K+-ATPase in Ehrlich ascites tumor by a membrane-bound protein kinase.
Carcinoma, Ehrlich Tumor
Size of native and denatured DNA of Ehrlich ascites tumour cells isolated in the presence of different protease concentrations.
Carcinoma, Embryonal
Appearance of nuclear protease activity after embryonal carcinoma cells undergo differentiation.
Carcinoma, Hepatocellular
A naturally occurring nonpolymerogenic mutant of alpha 1-antitrypsin characterized by prolonged retention in the endoplasmic reticulum.
Carcinoma, Hepatocellular
A novel alkaline protease with antiproliferative activity from fresh fruiting bodies of the toxic wild mushroom Amanita farinosa.
Carcinoma, Hepatocellular
A novel trypsin-like serine protease (hepsin) with a putative transmembrane domain expressed by human liver and hepatoma cells.
Carcinoma, Hepatocellular
A unique trypsin-like protease associated with plasma membranes of rat liver.
Carcinoma, Hepatocellular
Activity of chromatin-bound protease from rat liver and Morris hepatomas.
Carcinoma, Hepatocellular
Activity-based proteome profiling of hepatoma cells during hepatitis C virus replication using protease substrate probes.
Carcinoma, Hepatocellular
Alpha-1-antitrypsin deficiency and hepatocellular carcinoma. Determination of Pi phenotypes using iso-electric focusing.
Carcinoma, Hepatocellular
Anti-Inflammatory Activity of Cyanobacterial Serine Protease Inhibitors Aeruginosin 828A and Cyanopeptolin 1020 in Human Hepatoma Cell Line Huh7 and Effects in Zebrafish (Danio rerio).
Carcinoma, Hepatocellular
Antitumour effects of a protease inhibitor, nelfinavir, in hepatocellular carcinoma cancer cells.
Carcinoma, Hepatocellular
Apoptotic protease activating factor-1 negatively regulates Wnt signaling in hepatocellular carcinoma.
Carcinoma, Hepatocellular
Association of insulin-degrading enzyme with a 70 kDa cytosolic protein in hepatoma cells.
Carcinoma, Hepatocellular
cFLIPL prevents TRAIL-induced apoptosis of hepatocellular carcinoma cells by inhibiting the lysosomal pathway of apoptosis.
Carcinoma, Hepatocellular
Clinical outcomes in patients with chronic hepatitis C after direct-acting antiviral treatment: a prospective cohort study.
Carcinoma, Hepatocellular
Comprehensive analysis of ubiquitin-specific protease 1 reveals its importance in hepatocellular carcinoma.
Carcinoma, Hepatocellular
Correction for: Ubiquitin-specific protease 4 promotes metastasis of hepatocellular carcinoma by increasing TGF-? signaling-induced epithelial-mesenchymal transition.
Carcinoma, Hepatocellular
Correction: The Antimetastatic Effects of Resveratrol on Hepatocellular Carcinoma through the Downregulation of a Metastasis-Associated Protease by SP-1 Modulation.
Carcinoma, Hepatocellular
Creation and characterization of a cell-death reporter cell line for hepatitis C virus infection.
Carcinoma, Hepatocellular
Curcumin Upregulates Antioxidant Defense, Lon Protease, and Heat-Shock Protein 70 Under Hyperglycemic Conditions in Human Hepatoma Cells.
Carcinoma, Hepatocellular
Differential analysis of N-glycoproteome between hepatocellular carcinoma and normal human liver tissues by combination of multiple protease digestion and solid phase based labeling.
Carcinoma, Hepatocellular
Differential regulation of gene activity and chromatin structure within the human serpin gene cluster at 14q32.1 in macrophage microcell hybrids.
Carcinoma, Hepatocellular
Differential susceptibilities of murine hepatoma 1c1c7 and Tao cells to the lysosomal photosensitizer NPe6: influence of aryl hydrocarbon receptor on lysosomal fragility and protease contents.
Carcinoma, Hepatocellular
Effect of alpha-2-macroglobulin on cytokine-mediated human C-reactive protein production.
Carcinoma, Hepatocellular
Effect of protease inhibitors on albumin secretion in hepatoma cells.
Carcinoma, Hepatocellular
Elevated carbohydrate phosphotransferase activity in human hepatoma and phosphorylation of cathepsin D.
Carcinoma, Hepatocellular
Enhanced mitochondrial biogenesis is associated with increased expression of the mitochondrial ATP-dependent Lon protease.
Carcinoma, Hepatocellular
Entry of duck hepatitis B virus into primary duck liver and kidney cells after discovery of a fusogenic region within the large surface protein.
Carcinoma, Hepatocellular
Establishment of a clonal strain of hepatoma cells derived from Morris hepatoma 8999.
Carcinoma, Hepatocellular
Functional alpha 1 protease inhibitor produced by a human hepatoma cell line.
Carcinoma, Hepatocellular
HAI-2 is epigenetically downregulated in human hepatocellular carcinoma, and its Kunitz domain type 1 is critical for anti-invasive functions.
Carcinoma, Hepatocellular
Hepatitis C Virus NS3 Protein Plays a Dual Role in WRN-Mediated Repair of Non-Homologous End Joining.
Carcinoma, Hepatocellular
Hepsin, a cell surface serine protease identified in hepatoma cells, is overexpressed in ovarian cancer.
Carcinoma, Hepatocellular
HIV protease inhibitors protect apolipoprotein B from degradation by the proteasome: a potential mechanism for protease inhibitor-induced hyperlipidemia.
Carcinoma, Hepatocellular
ICE-like protease (caspase) is involved in transforming growth factor beta1-mediated apoptosis in FaO rat hepatoma cell line.
Carcinoma, Hepatocellular
Identification of potential transmembrane protease serine 4 inhibitors as anti-cancer agents by integrated computational approach.
Carcinoma, Hepatocellular
In vitro association of mitochondrial ATP- dependent protease with mitochondrial heat-shock proteins.
Carcinoma, Hepatocellular
Increase in the nuclear localization of PTEN by the Toxoplasma GRA16 protein and subsequent induction of p53-dependent apoptosis and anticancer effect.
Carcinoma, Hepatocellular
Increased activity of a neutral protease in cytosol from rat hepatoma induced by N-2-fluorenylacetamide.
Carcinoma, Hepatocellular
Induction of a novel Ca2+-dependent protease in preneoplastic and neoplastic liver tissues during rat liver carcinogenesis.
Carcinoma, Hepatocellular
Inhibition of experimental metastasis by enzyme inhibitors from microorganisms and plants.
Carcinoma, Hepatocellular
Inhibition of hepatitis C virus replication by semi-synthetic derivatives of glycopeptide antibiotics.
Carcinoma, Hepatocellular
Inhibition of hepatocellular carcinoma invasion by suppression of claudin-10 in HLE cells.
Carcinoma, Hepatocellular
Inhibition of insulin degradation by hepatoma cells after microinjection of monoclonal antibodies to a specific cytosolic protease.
Carcinoma, Hepatocellular
Inhibition of Plasmodium Hepatic Infection by Antiretroviral Compounds.
Carcinoma, Hepatocellular
Inhibition of SENP6-Induced Radiosensitization of Human Hepatocellular Carcinoma Cells by Blocking Radiation-Induced NF-?B Activation.
Carcinoma, Hepatocellular
Inhibitory effects of the recombinant human serine protease inhibitor Hespintor on the proliferation, migration and invasion of hepatocellular carcinoma cells.
Carcinoma, Hepatocellular
Interleukin-6 in transcatheter arterial embolization for patients with hepatocellular carcinoma. Effects of serine protease inhibitor.
Carcinoma, Hepatocellular
Isolation and characterization of a trypsin-chymotrypsin inhibitor from the seeds of green lentil (Lens culinaris).
Carcinoma, Hepatocellular
Isolation of alliumin, a novel protein with antimicrobial and antiproliferative activities from multiple-cloved garlic bulbs.
Carcinoma, Hepatocellular
Liver Cancer-Specific Serine Protease Inhibitor Kazal Is a Potentially Novel Biomarker for the Early Detection of Hepatocellular Carcinoma.
Carcinoma, Hepatocellular
Mouse matriptase-2: identification, characterization and comparative mRNA expression analysis with mouse hepsin in adult and embryonic tissues.
Carcinoma, Hepatocellular
Multiple forms of an angiogenesis factor: basic fibroblast growth factor.
Carcinoma, Hepatocellular
Novel RNA-binding activity of NQO1 promotes SERPINA1 mRNA translation.
Carcinoma, Hepatocellular
Oxidative stress and activation of proteasome protease during serum deprivation-induced apoptosis in rat hepatoma cells; inhibition of cell death by melatonin.
Carcinoma, Hepatocellular
Peptide network for detection of tissue-remodeling enzyme in the prognosis of hepatocellular carcinoma.
Carcinoma, Hepatocellular
Proteins and RNA in mouse L cell core nucleoli and nucleolar matrix.
Carcinoma, Hepatocellular
Public health impact of comprehensive hepatitis C screening and treatment in the French baby-boomer population.
Carcinoma, Hepatocellular
Purification, characterization and localization of serine protease of Morris hepatoma 8999.
Carcinoma, Hepatocellular
Real-world safety and efficacy of sofosbuvir and ledipasvir for elderly patients.
Carcinoma, Hepatocellular
Reduced ubiquitin-specific protease 9X expression induced by RNA interference inhibits the bioactivity of hepatocellular carcinoma cells.
Carcinoma, Hepatocellular
Regulation of insulin, epidermal growth factor, and transforming growth factor-alpha levels by growth factor-degrading enzymes.
Carcinoma, Hepatocellular
RNA interference against urokinase in hepatocellular carcinoma xenografts in nude mice.
Carcinoma, Hepatocellular
Role of plasminogen activator in the morphological alterations induced by derivatives of adenosine cyclic 3':5'-monophosphate in hepatoma tissue culture cells.
Carcinoma, Hepatocellular
Secretion of extracellular matrix (fibronectin), growth factor (transforming growth factor beta) and protease (cathepsin D) by hepatoma cells.
Carcinoma, Hepatocellular
Serine protease inhibitor Kazal type 1 (SPINK1) downregulates E-cadherin and induces EMT of hepatoma cells to promote hepatocellular carcinoma metastasis via the MEK/ERK signaling pathway.
Carcinoma, Hepatocellular
Serine protease inhibitor kazal-type 6 inhibits tumorigenesis of human hepatocellular carcinoma cells via its extracellular action.
Carcinoma, Hepatocellular
SerpinB3 induces dipeptidyl-peptidase IV/CD26 expression and its metabolic effects in hepatocellular carcinoma.
Carcinoma, Hepatocellular
SerpinB3 Promotes Pro-fibrogenic Responses in Activated Hepatic Stellate Cells.
Carcinoma, Hepatocellular
Serum protease inhibitors in opisthorchiasis, hepatoma, cholangiocarcinoma, and other liver diseases.
Carcinoma, Hepatocellular
Small interfering RNA urokinase silencing inhibits invasion and migration of human hepatocellular carcinoma cells.
Carcinoma, Hepatocellular
Stable expression and cell-specific chromatin structure of human alpha1-antitrypsin cosmid transgenes in rat hepatoma cells.
Carcinoma, Hepatocellular
Studies on the mechanisms of invasion in cancer. 3. Purification of a neutral protease of rat ascites hepatoma cell associated with production of chemotactic factor for cancer cells.
Carcinoma, Hepatocellular
SUMO-specific protease 2 (SENP2) functions as a tumor suppressor in osteosarcoma via SOX9 degradation.
Carcinoma, Hepatocellular
The 39-kDa protein regulates LRP activity in cultured endothelial and smooth muscle cells.
Carcinoma, Hepatocellular
The Antimetastatic Effects of Resveratrol on Hepatocellular Carcinoma through the Downregulation of a Metastasis-Associated Protease by SP-1 Modulation.
Carcinoma, Hepatocellular
The design of a potent inhibitor of the hepatitis C virus NS3 protease: BILN 2061--from the NMR tube to the clinic.
Carcinoma, Hepatocellular
The low density lipoprotein receptor-related protein mediates the cellular degradation of tissue factor pathway inhibitor.
Carcinoma, Hepatocellular
The protease-inhibitor SerpinB3 as a critical modulator of the stem-like subset in human cholangiocarcinoma.
Carcinoma, Hepatocellular
The serine protease from rat liver and hepatoma 8999. Location and role in mitochondrial protein degradation.
Carcinoma, Hepatocellular
Thyroid hormone enhanced human hepatoma cell motility involves brain-specific serine protease 4 activation via ERK signaling.
Carcinoma, Hepatocellular
TKP, a Serine Protease from Trichosanthes kirilowii, Inhibits Cell Proliferation by Blocking Aerobic Glycolysis in Hepatocellular Carcinoma Cells.
Carcinoma, Hepatocellular
Ubiquitin-speci?c protease 4 promotes metastasis of hepatocellular carcinoma by increasing TGF-? signaling-induced epithelial-mesenchymal transition.
Carcinoma, Hepatocellular
Ubiquitin-specific protease 11 serves as a marker of poor prognosis and promotes metastasis in hepatocellular carcinoma.
Carcinoma, Hepatocellular
Ubiquitin-Specific Protease 22/Silent Information Regulator 1 Axis Plays a Pivotal Role in the Prognosis and 5-Fluorouracil Resistance in Hepatocellular Carcinoma.
Carcinoma, Hepatocellular
Ubiquitin-specific protease 4 promotes hepatocellular carcinoma progression via cyclophilin A stabilization and deubiquitination.
Carcinoma, Hepatocellular
USP22 promotes hypoxia-induced hepatocellular carcinoma stemness by a HIF1?/USP22 positive feedback loop upon TP53 inactivation.
Carcinoma, Hepatocellular
USP5 promotes tumorigenesis and progression of pancreatic cancer by stabilizing FoxM1 protein.
Carcinoma, Hepatocellular
Virosome-mediated implantation of red cell band 3 into the plasma membrane of cultured hepatoma cells.
Carcinoma, Hepatocellular
[Carbohydrate phosphotransferase in human hepatoma and phosphorylation of cathepsin D]
Carcinoma, Hepatocellular
[Effect of ERK/AP-1 signaling pathway on proliferation of hepatoma cells induced by PAR-2 agonists]
Carcinoma, Hepatocellular
[Effect of protease activated receptor-2 agonists on proliferation of hepatoma cells.]
Carcinoma, Hepatocellular
[Proteolytic degradation of nuclear matrix proteins in the rat liver, Zajdela's hepatoma and hepatoma 22A in the presence of ATP]
Carcinoma, Intraductal, Noninfiltrating
Differentially expressed genes regulating the progression of ductal carcinoma in situ to invasive breast cancer.
Carcinoma, Intraductal, Noninfiltrating
Elafin is downregulated during breast and ovarian tumorigenesis but its residual expression predicts recurrence.
Carcinoma, Intraductal, Noninfiltrating
Role of COX-2 in epithelial-stromal cell interactions and progression of ductal carcinoma in situ of the breast.
Carcinoma, Intraductal, Noninfiltrating
Validation of immunolocalization of the urokinase receptor expression in ductal carcinoma in situ of the breast: comparison with detection by non-isotopic in-situ hybridization.
Carcinoma, Lewis Lung
Viola Yedoensis Suppresses Cell Invasion by Targeting the Protease and NF-?B Activities in A549 and Lewis Lung Carcinoma Cells.
Carcinoma, Lewis Lung
[Inhibitory effect and the mechanism of Astragalus polysaccharide combined with cisplatin on growth of inplanted Lewis lung carcinoma in mice].
Carcinoma, Lobular
Elastosis in breast carcinoma: II. Association of protease inhibitors with immature elastic fibres.
Carcinoma, Mucoepidermoid
Comparative Analysis of P63, Maspin and Matrix Metalloproteinase 2 Expression in Mucoepidermoid Carcinoma and Adenoid Cystic Carcinoma of Salivary Glands.
Carcinoma, Mucoepidermoid
Metallothionein Expression and its Influence on the In Vitro Biological Behavior of Mucoepidermoid Carcinoma.
Carcinoma, Non-Small-Cell Lung
ADAM10 overexpression in human non-small cell lung cancer correlates with cell migration and invasion through the activation of the Notch1 signaling pathway.
Carcinoma, Non-Small-Cell Lung
Anti-cancer activity of the novel 2-hydroxydiarylamide derivatives IMD-0354 and KRT1853 through suppression of cancer cell invasion, proliferation, and survival mediated by TMPRSS4.
Carcinoma, Non-Small-Cell Lung
Clinical and prognostic importance of XIAP and USP8 in advanced stages of non-small cell lung cancer.
Carcinoma, Non-Small-Cell Lung
Differential regulation of protease and extracellular matrix protein expression by transforming growth factor-beta 1 in non-small cell lung cancer cells and normal human bronchial epithelial cells.
Carcinoma, Non-Small-Cell Lung
Enhancement of Apo2L/TRAIL (tumor necrosis factor-related apoptosis-inducing ligand)-induced apoptosis in non-small cell lung cancer cell lines by chemotherapeutic agents without correlation to the expression level of cellular protease caspase-8 inhibitory protein.
Carcinoma, Non-Small-Cell Lung
Global Decrease of Histone H3K27 Acetylation in ZEB1-Induced Epithelial to Mesenchymal Transition in Lung Cancer Cells.
Carcinoma, Non-Small-Cell Lung
Narrowing of the region of allelic loss in 21q11-21 in squamous non-small cell lung carcinoma and cloning of a novel ubiquitin-specific protease gene from the deleted segment.
Carcinoma, Non-Small-Cell Lung
Nuclear localization of apoptosis protease activating factor-1 predicts survival after tumor resection in early-stage non-small cell lung cancer.
Carcinoma, Non-Small-Cell Lung
Overexpression of ubiquitin-specific protease 22 predicts poor survival in patients with early-stage non-small cell lung cancer.
Carcinoma, Non-Small-Cell Lung
Plasminogen Activator Inhibitor-2 Plays a Leading Prognostic Role among Protease Families in Non-Small Cell Lung Cancer.
Carcinoma, Non-Small-Cell Lung
Prognostic relevance of TTF-1 and MMP-9 expression in advanced lung adenocarcinoma.
Carcinoma, Non-Small-Cell Lung
Protease Serine S1 Family Member 8 (PRSS8) Inhibits Tumor Growth In Vitro and In Vivo in Human Non-Small Cell Lung Cancer.
Carcinoma, Non-Small-Cell Lung
Targeted gene therapy of the HSV-TK/hIL-12 fusion gene controlled by the hSLPI gene promoter of human non-small cell lung cancer in vitro.
Carcinoma, Non-Small-Cell Lung
Testes-specific protease 50 as an independent risk factor for poor prognosis in patients with non-small cell lung cancer.
Carcinoma, Non-Small-Cell Lung
The roles of MASPIN expression and subcellular localization in non-small cell lung cancer.
Carcinoma, Non-Small-Cell Lung
Tumor suppressive microRNA-124a inhibits stemness and enhances gefitinib sensitivity of non-small cell lung cancer cells by targeting ubiquitin-specific protease 14.
Carcinoma, Non-Small-Cell Lung
Ubiquitin-specific protease 22 is critical to in vivo angiogenesis, growth and metastasis of non-small cell lung cancer.
Carcinoma, Non-Small-Cell Lung
[Expression of USP9X in Non-small Cell Lung Cancer and Its Clinical Significance].
Carcinoma, Ovarian Epithelial
Expression of the serine protease matriptase and its inhibitor HAI-1 in epithelial ovarian cancer: correlation with clinical outcome and tumor clinicopathological parameters.
Carcinoma, Ovarian Epithelial
Induction of human tumor-associated differentially expressed gene-12 (TADG-12/TMPRSS3)-specific cytotoxic T lymphocytes in human lymphocyte antigen-A2.1-positive healthy donors and patients with advanced ovarian cancer.
Carcinoma, Ovarian Epithelial
Protease inhibitor SERPINA1 expression in epithelial ovarian cancer.
Carcinoma, Ovarian Epithelial
Ubiquitin specific protease 22 promotes cell proliferation and tumor growth of epithelial ovarian cancer through synergy with transforming growth factor ?1.
Carcinoma, Ovarian Epithelial
Ubiquitin-specific protease 14 (USP14) regulates cellular proliferation and apoptosis in epithelial ovarian cancer.
Carcinoma, Renal Cell
A phase II study of interferon-alpha, interleukin-2 and 5-fluorouracil in advanced renal carcinoma: clinical data and laboratory evidence of protease activation.
Carcinoma, Renal Cell
Characterization and purification of a guanidinobenzoatase: a possible marker of human renal carcinoma.
Carcinoma, Renal Cell
Downregulation of ubiquitin-specific protease 2 possesses prognostic and diagnostic value and promotes the clear cell renal cell carcinoma progression.
Carcinoma, Renal Cell
Effects of Open versus Laparoscopic Nephrectomy Techniques on Oxidative Stress Markers in Patients with Renal Cell Carcinoma.
Carcinoma, Renal Cell
Expression of protease activated receptor-2 is reduced in renal cell carcinoma biopsies and cell lines.
Carcinoma, Renal Cell
Expression of serine protease matriptase in renal cell carcinoma: correlation of tissue microarray immunohistochemical expression analysis results with clinicopathological parameters.
Carcinoma, Renal Cell
High density of tryptase-positive mast cells in patients with renal cell carcinoma on hemodialysis: correlation with expression of stem cell factor and protease activated receptor-2.
Carcinoma, Renal Cell
Immunostaining of intermediate filament proteins in paraffin sections. Evaluation of optimal protease treatment to improve the immunoreactivity.
Carcinoma, Renal Cell
Improving the efficacy of proteasome inhibitors in the treatment of renal cell carcinoma by combination with the human immunodeficiency virus (HIV)-protease inhibitors lopinavir or nelfinavir.
Carcinoma, Renal Cell
Methylation of tumour suppressor genes APAF-1 and DAPK-1 and in vitro effects of demethylating agents in bladder and kidney cancer.
Carcinoma, Renal Cell
microRNA-186 Suppresses Cell Proliferation and Metastasis Through Targeting Sentrin Specific Protease 1 in Renal Cell Carcinoma.
Carcinoma, Renal Cell
T-cell receptor zeta-chain expression on tumor-infiltrating lymphocytes from renal cell carcinoma.
Carcinoma, Renal Cell
The impact of peptidase activity on clear cell renal cell carcinoma survival.
Carcinoma, Renal Cell
The protease activated receptor 1 gene variation IVSn -14A>T is associated with distant metastasis and cancer-specific survival in renal cell carcinoma.
Carcinoma, Renal Cell
Tumor suppressor activity and epigenetic inactivation of hepatocyte growth factor activator inhibitor type 2/SPINT2 in papillary and clear cell renal cell carcinoma.
Carcinoma, Renal Cell
Two-dimensional polyacrylamide gel electrophoresis of the protease SP220K, a renal cell carcinoma marker.
Carcinoma, Renal Cell
USP46 Inhibits Cell Proliferation in Lung Cancer through PHLPP1/AKT Pathway.
Carcinoma, Squamous Cell
A Novel Tumor Suppressor SPINK5 Serves as an Independent Prognostic Predictor for Patients with Head and Neck Squamous Cell Carcinoma.
Carcinoma, Squamous Cell
Antitumor potential of SLPI promoter controlled recombinant caspase-3 expression in laryngeal carcinoma.
Carcinoma, Squamous Cell
Association and dissociation of a protease and its inhibitor on the surface of lung squamous cell carcinoma cells.
Carcinoma, Squamous Cell
Association between Time on Protease Inhibitors and the Incidence of Squamous Cell Carcinoma of the Anus among U.S. Male Veterans.
Carcinoma, Squamous Cell
c-Met-induced epithelial carcinogenesis is initiated by the serine protease matriptase.
Carcinoma, Squamous Cell
Calcium-mediated degradation of epidermal growth factor receptor in dislodged A431 cells and membrane preparations.
Carcinoma, Squamous Cell
CEBPB knockdown sensitizes nasopharyngeal carcinoma cells to cisplatin by promoting the expression of serine protease inhibitor Kazal-type 5.
Carcinoma, Squamous Cell
Characterization of monoclonal antibodies directed against squamous cell carcinoma antigens: report of the TD-10 Workshop.
Carcinoma, Squamous Cell
Clinical experience with a protease inhibitor [N,N-dimethylcarbamoylmethyl 4-(4-guanidinobenzoyloxy)-phenylacetate] methanesulfate for prevention of recurrence of carcinoma of the mouth and in treatment of terminal carcinoma.
Carcinoma, Squamous Cell
Clinical validation of combined serological biomarkers for improved hepatocellular carcinoma diagnosis in 961 patients.
Carcinoma, Squamous Cell
Cloning and expression of a novel hepatitis B virus-binding protein from HepG2 cells.
Carcinoma, Squamous Cell
Delineation of matriptase protein expression by enzymatic gene trapping suggests diverging roles in barrier function, hair formation, and squamous cell carcinogenesis.
Carcinoma, Squamous Cell
Differential effects of periopathogens on host protease inhibitors SLPI, elafin, SCCA1, and SCCA2.
Carcinoma, Squamous Cell
Differential expression of a novel serine protease homologue in squamous cell carcinoma of the head and neck.
Carcinoma, Squamous Cell
Effect of biological behavior and clinical significance of maspin gene on cervical squamous carcinoma SiHa cell.
Carcinoma, Squamous Cell
Effects of serine protease inhibitor FOY-305 and heparin on the growth of squamous cell carcinoma.
Carcinoma, Squamous Cell
EGF stimulates Cdc42-dependent translocation of SCC antigen to the plasma membrane.
Carcinoma, Squamous Cell
Elevated expression of squamous cell carcinoma antigen (SCCA) is associated with human breast carcinoma.
Carcinoma, Squamous Cell
Enzymatic Degradation of Biofilm by Metalloprotease From Microbacterium sp. SKS10.
Carcinoma, Squamous Cell
Expression of the serine protease DESC1 correlates directly with normal keratinocyte differentiation and inversely with head and neck squamous cell carcinoma progression.
Carcinoma, Squamous Cell
High Expression of Ubiquitin-Specific Protease 8 (USP8) Is Associated with Poor Prognosis in Patients with Cervical Squamous Cell Carcinoma.
Carcinoma, Squamous Cell
Human papillomavirus infection in head and neck cancer: The role of the secretory leukocyte protease inhibitor.
Carcinoma, Squamous Cell
Identification of aberrantly regulated genes in diseased skin using the cDNA differential display technique.
Carcinoma, Squamous Cell
Inhibition of apoptosis in human tumour cells by the tumour-associated serpin, SCC antigen-1.
Carcinoma, Squamous Cell
Inhibition of epidermal growth factor-induced invasion by dexamethasone and AP-1 decoy in human squamous cell carcinoma cell lines.
Carcinoma, Squamous Cell
Knockdown of Ubiquitin-Specific Protease 53 Enhances the Radiosensitivity of Human Cervical Squamous Cell Carcinoma by Regulating DNA Damage-Binding Protein 2.
Carcinoma, Squamous Cell
Loss of heterozygosity in mammary serine protease inhibitor (maspin) and p53 at chromosome 17 and 18 in oral cavity squamous cell carcinoma.
Carcinoma, Squamous Cell
Maspin, p53, p63, and Ki-67 in epithelial lesions of the tongue: from hyperplasia through dysplasia to carcinoma.
Carcinoma, Squamous Cell
Mast cell chymase is present in uterine cervical carcinoma and it detaches viable and growing cervical squamous carcinoma cells from substratum in vitro.
Carcinoma, Squamous Cell
miR-186 promotes tumor growth in cutaneous squamous cell carcinoma by inhibiting apoptotic protease activating factor-1.
Carcinoma, Squamous Cell
Novel forms of squamous cell carcinoma antigen transcripts produced by alternative splicing.
Carcinoma, Squamous Cell
Oncogenic Ras induces inflammatory cytokine production by upregulating the squamous cell carcinoma antigens SerpinB3/B4.
Carcinoma, Squamous Cell
Optical biosensor differentiates signaling of endogenous PAR1 and PAR2 in A431 cells.
Carcinoma, Squamous Cell
Overexpression of squamous cell carcinoma antigen in idiopathic pulmonary fibrosis: clinicopathological correlations.
Carcinoma, Squamous Cell
Paracrine factor and cell-cell contact-mediated induction of protease and c-ets gene expression in malignant keratinocyte/dermal fibroblast cocultures.
Carcinoma, Squamous Cell
Protease inhibitor suppression of colon and anal gland carcinogenesis induced by dimethylhydrazine.
Carcinoma, Squamous Cell
PRSS8 methylation and its significance in esophageal squamous cell carcinoma.
Carcinoma, Squamous Cell
Rearrangement of squamous cell carcinoma antigen genes--detection of SCCA fusion transcripts.
Carcinoma, Squamous Cell
Role of membrane type 1-matrix metalloproteinase and gelatinase A in head and neck squamous cell carcinoma invasion in vitro.
Carcinoma, Squamous Cell
SCCA2 inhibits TNF-mediated apoptosis in transfected HeLa cells. The reactive centre loop sequence is essential for this function and TNF-induced cathepsin G is a candidate target.
Carcinoma, Squamous Cell
Serine protease inhibitor activity of recombinant squamous cell carcinoma antigen towards chymotrypsin, as demonstrated by sodium dodecyl sulfate-polyacrylamide gel electrophoresis.
Carcinoma, Squamous Cell
Squamous cell carcinoma antigen 1 promotes caspase-8-mediated apoptosis in response to endoplasmic reticulum stress while inhibiting necrosis induced by lysosomal injury.
Carcinoma, Squamous Cell
Squamous cell carcinoma antigen is a new member of the serine protease inhibitors.
Carcinoma, Squamous Cell
Squamous cell carcinoma antigen-IgM (SCCA-IgM) is associated with interstitial lung disease in systemic sclerosis.
Carcinoma, Squamous Cell
The antileukoprotease secretory leukocyte protease inhibitor (SLPI) and its role in the prevention of HPV-infections in head and neck squamous cell carcinoma.
Carcinoma, Squamous Cell
The enigma PAI-2. Gene expression, evolutionary and functional aspects.
Carcinoma, Squamous Cell
The level of secretory leukocyte protease inhibitor is decreased in metastatic head and neck squamous cell carcinoma.
Carcinoma, Squamous Cell
The role of interleukin-4 and interleukin-13 in the non-immunologic aspects of asthma pathogenesis.
Carcinoma, Squamous Cell
The serine protease inhibitor of Kazal-type 9 (SPINK9) is expressed in lichen simplex chronicus, actinic keratosis and squamous cell carcinoma.
Carcinoma, Squamous Cell
Ubiquitin-specific protease 4 promotes TNF-?-induced apoptosis by deubiquitination of RIP1 in head and neck squamous cell carcinoma.
Carcinoma, Squamous Cell
Urokinase-type plasminogen activator and its inhibitor plasminogen activator inhibitor-1.
Carcinoma, Squamous Cell
Zebrafish modeling reveals that SPINT1 regulates the aggressiveness of skin cutaneous melanoma and its crosstalk with tumor immune microenvironment.
Carcinoma, Squamous Cell
[Analysis of the Squamous Cell Carcinoma Antigen (SCCA) Which Has a Significant Difference in Values between CLIA and FEIA--Case Report of Extra Glycosylation in SCCA].
Carcinoma, Squamous Cell
[Demonstration of an epidermal SH-protease inhibitor in normal epithelium and in some human neoplasms--an immunological study (author's transl)]
Carcinoma, Squamous Cell
[Hydrophobicity of reactive site loop of SCCA1 affects its binding to HBV]
Carcinoma, Transitional Cell
Amiloride and urinary trypsin inhibitor inhibit urothelial cancer invasion.
Carcinoma, Transitional Cell
Methylation of tumour suppressor genes APAF-1 and DAPK-1 and in vitro effects of demethylating agents in bladder and kidney cancer.
Carcinoma, Transitional Cell
Protease and plasminogen activator activity in human bladder carcinoma.
Cardiac Output, Low
Is thrombosis a contributor to heart failure pathophysiology? Possible mechanisms, therapeutic opportunities, and clinical investigation challenges.
Cardiomegaly
Deubiquitinase Ubiquitin-Specific Protease 10 Deficiency Regulates Sirt6 signaling and Exacerbates Cardiac Hypertrophy.
Cardiomegaly
Pregnancy-Associated Cardiac Hypertrophy in Corin-Deficient Mice: Observations in a Transgenic Model of Preeclampsia.
Cardiomegaly
Transmembrane tumor necrosis factor alpha attenuates pressure-overload cardiac hypertrophy via tumor necrosis factor receptor 2.
Cardiomegaly
Ubiquitin-specific protease 14 regulates cardiac hypertrophy progression by increasing GSK-3? phosphorylation.
Cardiomegaly
Ubiquitin-specific protease 19 blunts pathological cardiac hypertrophy via inhibition of the TAK1-dependent pathway.
Cardiomegaly
Ubiquitin-Specific Protease 4 Is an Endogenous Negative Regulator of Pathological Cardiac Hypertrophy.
Cardiomyopathies
Corin Overexpression Reduces Myocardial Infarct Size and Modulates Cardiomyocyte Apoptotic Cell Death.
Cardiomyopathies
Doxorubicin cardiomyopathy via TLR-2 stimulation: potential for prevention using current anti-retroviral inhibitors such as ritonavir and nelfinavir.
Cardiomyopathies
Implications of protease activation in cardiac dysfunction and development of genetic cardiomyopathy in hamsters.
Cardiomyopathies
Inhibition of Coxsackievirus-associated dystrophin cleavage prevents cardiomyopathy.
Cardiomyopathies
Lysosomal and nonlysosomal proteolytic activities in experimental diabetic cardiomyopathy.
Cardiomyopathies
Prelamin A mediates myocardial inflammation in dilated and HIV-associated cardiomyopathies.
Cardiomyopathies
Severe dystrophic cardiomyopathy caused by the enteroviral protease 2A-mediated C-terminal dystrophin cleavage fragment.
Cardiomyopathies
Tadalafil Treatment Delays the Onset of Cardiomyopathy in Dystrophin-Deficient Hearts.
Cardiomyopathies
[Instability of alpha-2-macroglobulin protease complex in familial cardiomyopathy]
Cardiomyopathy, Dilated
Cardiac-Specific Overexpression of Catalytically Inactive Corin Reduces Edema, Contractile Dysfunction, and Death in Mice with Dilated Cardiomyopathy.
Cardiomyopathy, Dilated
Light chain 2 profile and activity of human ventricular myosin during dilated cardiomyopathy. Identification of a causal agent for impaired myocardial function.
Cardiomyopathy, Dilated
Natriuretic Peptide Processing in Patients with and Without Left Ventricular Dysfunction.
Cardiotoxicity
Atazanavir induced first degree atrioventricular block and ventricular tachycardia: a case report.
Cardiotoxicity
Doxorubicin cardiomyopathy via TLR-2 stimulation: potential for prevention using current anti-retroviral inhibitors such as ritonavir and nelfinavir.
Cardiotoxicity
MMP inhibitors attenuate doxorubicin cardiotoxicity by preventing intracellular and extracellular matrix remodeling.
Cardiotoxicity
Ultra-rapid cardiotoxicity of the hepatitis C virus protease inhibitor BILN 2061 in the urokinase-type plasminogen activator mouse.
Cardiovascular Diseases
A cross-sectional study to evaluate the association of hyperbilirubinaemia on markers of cardiovascular disease, neurocognitive function, bone mineral density and renal markers in HIV-1 infected subjects on protease inhibitors.
Cardiovascular Diseases
A High-Throughput Luciferase Assay to Evaluate Proteolysis of the Single-Turnover Protease PCSK9.
Cardiovascular Diseases
A novel fibrinolytic enzyme from marine Pseudomonas aeruginosa KU1 and its rapid in vivo thrombolysis with little haemolysis.
Cardiovascular Diseases
A patient with HIV and tuberculosis with diminished clopidogrel response.
Cardiovascular Diseases
Activation of HtrA2, a mitochondrial serine protease mediates apoptosis: current knowledge on HtrA2 mediated myocardial ischemia/reperfusion injury.
Cardiovascular Diseases
ADAMTS-5 Decreases in Coronary Arteries and Plasma from Patients with Coronary Artery Disease.
Cardiovascular Diseases
Antiretroviral therapy as a cardiovascular disease risk factor: fact or fiction? A review of clinical and surrogate outcome studies.
Cardiovascular Diseases
Association between protease inhibitor use and increased cardiovascular risk in patients infected with human immunodeficiency virus: a systematic review.
Cardiovascular Diseases
C5a stimulates production of plasminogen activator inhibitor-1 in human mast cells and basophils.
Cardiovascular Diseases
Cardiovascular considerations in patients treated with HIV protease inhibitors.
Cardiovascular Diseases
Cardiovascular disease and use of contemporary protease inhibitors: the D:A:D international prospective multicohort study.
Cardiovascular Diseases
Cardiovascular disease in patients infected with the human immunodeficiency virus.
Cardiovascular Diseases
Cardiovascular risks associated with protease inhibitors for the treatment of HIV.
Cardiovascular Diseases
Change to atazanavir/ritonavir treatment improves lipids but not endothelial function in patients on stable antiretroviral therapy.
Cardiovascular Diseases
Cholesterol Screening and Statin Prescription is Low Among HIV-Infected Patients on Protease-Inhibitor Regimens in Botswana.
Cardiovascular Diseases
Coagulation factor and protease pathways in thrombosis and cardiovascular disease.
Cardiovascular Diseases
CONSENSUS STATEMENT BY THE AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS AND AMERICAN COLLEGE OF ENDOCRINOLOGY ON THE COMPREHENSIVE TYPE 2 DIABETES MANAGEMENT ALGORITHM - 2019 EXECUTIVE SUMMARY.
Cardiovascular Diseases
CONSENSUS STATEMENT BY THE AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS AND AMERICAN COLLEGE OF ENDOCRINOLOGY ON THE COMPREHENSIVE TYPE 2 DIABETES MANAGEMENT ALGORITHM - 2020 EXECUTIVE SUMMARY.
Cardiovascular Diseases
Current IGFBP-Related Biomarker Research in Cardiovascular Disease-We Need More Structural and Functional Information in Clinical Studies.
Cardiovascular Diseases
Cystatin C in heart failure is nothing more than a bystander of glomerular filtration.
Cardiovascular Diseases
Cystatins: biochemical and structural properties, and medical relevance.
Cardiovascular Diseases
Cysteinyl cathepsins and mast cell proteases in the pathogenesis and therapeutics of cardiovascular diseases.
Cardiovascular Diseases
Distinct encounter complexes of PAI-1 with plasminogen activators and vitronectin revealed by changes in the conformation and dynamics of the reactive center loop.
Cardiovascular Diseases
Efavirenz and ritonavir-boosted lopinavir use exhibited elevated markers of atherosclerosis across age groups in people living with HIV in Ethiopia.
Cardiovascular Diseases
Effect of exercise on cardiac and metabolic outcomes in people living with HIV.
Cardiovascular Diseases
Effectiveness of switching from protease inhibitors to dolutegravir in combination with nucleoside reverse transcriptase inhibitors as maintenance antiretroviral therapy among HIV-positive patients.
Cardiovascular Diseases
Effects of Pitavastatin on Lipid Profiles in HIV-Infected Patients with Dyslipidemia and Receiving Atazanavir/Ritonavir: A Randomized, Double-Blind, Crossover Study.
Cardiovascular Diseases
Effects of plasminogen activator inhibitor-1-specific RNA aptamers on cell adhesion, motility, and tube formation.
Cardiovascular Diseases
Efficacy of the CCR5 antagonist maraviroc in reducing early, ritonavir-induced atherogenesis and advanced plaque progression in mice.
Cardiovascular Diseases
Emerging role of proprotein convertase subtilisin/kexin type-9 (PCSK-9) in inflammation and diseases.
Cardiovascular Diseases
Fibrinolytic enzymes from extremophilic microorganisms in the development of new thrombolytic therapies: Technological Prospecting.
Cardiovascular Diseases
Gilbert-Meulengracht's syndrome and pharmacogenetics: is jaundice just the tip of the iceberg?
Cardiovascular Diseases
High levels of cathepsin D and cystatin B are associated with increased risk of coronary events.
Cardiovascular Diseases
Highly active antiretroviral therapy-associated metabolic syndrome and cardiovascular risk.
Cardiovascular Diseases
Highly active antiretroviral therapy-associated metabolic syndrome: pathogenesis and cardiovascular risk.
Cardiovascular Diseases
HIV Protease Inhibitor Ritonavir Impairs Endothelial Function Via Reduction in Adipose Mass and Endothelial Leptin Receptor-Dependent Increases in NADPH Oxidase 1 (Nox1), C-C Chemokine Receptor Type 5 (CCR5), and Inflammation.
Cardiovascular Diseases
HIV-positive patients treated with protease inhibitors have vascular changes resembling those observed in atherosclerotic cardiovascular disease.
Cardiovascular Diseases
Human Immunodeficiency Virus Infection and Male Hypogonadism: A Review.
Cardiovascular Diseases
Hyperlipidemia in HIV-infected children treated with protease inhibitors: relevance for cardiovascular diseases.
Cardiovascular Diseases
Impact of CCR5, integrase and protease inhibitors on human endothelial cell function, stress, inflammation and senescence.
Cardiovascular Diseases
Impact of darunavir, atazanavir and lopinavir boosted with ritonavir on cultured human endothelial cells: beneficial effect of pravastatin.
Cardiovascular Diseases
In silico Prediction of Inhibitory Constant of Thrombin Inhibitors Using Machine Learning.
Cardiovascular Diseases
Inflammatory Biomarkers and Carotid Thickness in HIV Infected Patients under Antiretroviral Therapy, Undetectable HIV-1 Viral Load, and Low Cardiovascular Risk.
Cardiovascular Diseases
Investigation of low-dose ritonavir on human peripheral blood mononuclear cells using gene expression whole genome microarrays.
Cardiovascular Diseases
Levels of von Willebrand factor antigen and von Willebrand factor cleaving protease (ADAMTS13) activity predict clinical events in chronic heart failure.
Cardiovascular Diseases
Long-term cardiovascular risk with protease inhibitors and management of the dyslipidemia.
Cardiovascular Diseases
Low-density lipoprotein and ritonavir: an interaction between antiretrovirals and lipids mediated by P-glycoprotein.
Cardiovascular Diseases
Metabolic and cardiovascular complications of highly active antiretroviral therapy for HIV infection.
Cardiovascular Diseases
Metabolic complications and treatment of perinatally HIV-infected children and adolescents.
Cardiovascular Diseases
Metabolic syndrome associated with HIV and highly active antiretroviral therapy.
Cardiovascular Diseases
Microbial and fungal protease inhibitors--current and potential applications.
Cardiovascular Diseases
Morphologic and metabolic abnormalities in vertically HIV-infected children and youth.
Cardiovascular Diseases
Nelfinavir suppresses insulin signaling and nitric oxide production by human aortic endothelial cells: protective effects of thiazolidinediones.
Cardiovascular Diseases
New aspects in thrombotic research: complement induced switch in mast cells from a profibrinolytic to a prothrombotic phenotype.
Cardiovascular Diseases
New therapy strategies focusing on long term. Drugs' impact on heart is debated.
Cardiovascular Diseases
Obesity is associated with poor response to clopidogrel and an increased susceptibility to protease activated receptor-1 mediated platelet activation.
Cardiovascular Diseases
Post-exercise heart rate recovery in HIV-positive individuals on highly active antiretroviral therapy. Early indicator of cardiovascular disease?
Cardiovascular Diseases
Postprandial lipid effects of low-dose ritonavir vs. raltegravir in HIV-uninfected adults.
Cardiovascular Diseases
Premature atherosclerosis in HIV positive patients and cumulated time of exposure to antiretroviral therapy (SHIVA study).
Cardiovascular Diseases
Prolonged Exposure to Lopinavir Impairs Endothelium-dependent Hyperpolarization-mediated Relaxation in Rat Mesenteric Arteries.
Cardiovascular Diseases
Protease inhibitor exposure and increased risk of cardiovascular disease in HIV-infected patients.
Cardiovascular Diseases
Protease inhibitors and cardiovascular disease: analysis of the Los Angeles County adult spectrum of disease cohort.
Cardiovascular Diseases
Protein targets of inflammatory serine proteases and cardiovascular disease.
Cardiovascular Diseases
Regulation of epithelial sodium channel trafficking by proprotein convertase subtilisin/kexin type 9 (PCSK9).
Cardiovascular Diseases
Reviewing the cardiovascular complications of HIV infection after the introduction of highly active antiretroviral therapy.
Cardiovascular Diseases
Ritonavir inhibits the two main prasugrel bioactivation pathways in vitro: a potential drug-drug interaction in HIV patients.
Cardiovascular Diseases
Serum Cystatin C and Arterial Stiffness in Middle-Aged and Elderly Adults without Chronic Kidney Disease: A Population-Based Study.
Cardiovascular Diseases
Single fluorescence probes along the reactive center loop reveal site-specific changes during the latency transition of PAI-1.
Cardiovascular Diseases
Subclinical cardiovascular disease in patients starting contemporary protease inhibitors.
Cardiovascular Diseases
The discovery and characterization of a novel nucleotide-based thrombin inhibitor.
Cardiovascular Diseases
The dual role of the urokinase receptor system in pericellular proteolysis and cell adhesion: implications for cardiovascular function.
Cardiovascular Diseases
Therapeutic Potential of Targeting Protease Activated Receptors in Cardiovascular Diseases.
Cardiovascular Diseases
Use of metabolic drugs and fish oil in HIV-positive patients with metabolic complications and associations with dyslipidaemia and treatment targets.
Cardiovascular Diseases
Vascular injury, hypertension and coronary artery disease in human immunodeficiency virus infection.
Cardiovascular Diseases
Versatile Functionalization of Poly(methacrylic acid) Brushes with Series of Proteolytically Cleavable Peptides for Highly Sensitive Protease Assay.
Cardiovascular Diseases
Vitamin D insufficiency is associated with subclinical atherosclerosis in HIV-1-infected patients on combination antiretroviral therapy.
Cardiovascular Diseases
[Lipodystrophy and 'buffalo hump' during treatment with HIV protease inhibitors]
Carotid Artery Diseases
Interstitial collagenase (MMP-1) expression in human carotid atherosclerosis.
Carotid Artery Diseases
Low CD4+ T-cell count as a major atherosclerosis risk factor in HIV-infected women and men.
Carotid Artery Diseases
Profiling of Atherosclerotic Lesions by Gene and Tissue Microarrays Reveals PCSK6 as a Novel Protease in Unstable Carotid Atherosclerosis.
Carpal Tunnel Syndrome
Carpal tunnel syndrome in HIV-1 patients: a metabolic consequence of protease inhibitor use?
Carpal Tunnel Syndrome
Carpal tunnel syndrome in HIV-infected patients treated with highly active antiretroviral therapy: other case reports.
Castleman Disease
No effect of protease inhibitor on clinical and virological evolution of Castleman's disease in an HIV-1-infected patient.
Cat-Scratch Disease
IrSPI, a tick serine protease inhibitor involved in tick feeding and Bartonella henselae infection.
Cataract
alpha-Crystallin chaperone activity is reduced by calpain II in vitro and in selenite cataract.
Cataract
Cataract and the acceleration of calpain-induced beta-crystallin insolubilization occurring during normal maturation of rat lens.
Cataract
Cataractogenesis in transgenic mice containing the HIV-1 protease linked to the lens alpha A-crystallin promoter.
Cataract
Comparison in effect of different metal ions, pH and reducing agent on the protease activity in human hyper mature and mature cataract.
Cataract
Comparison of cell-permeable calpain inhibitors and E64 in reduction of cataract in cultured rat lenses.
Cataract
Cysteine protease activated by expression of HIV-1 protease in transgenic mice. MIP26 (aquaporin-0) cleavage and cataract formation in vivo and ex vivo.
Cataract
Defining a link between gap junction communication, proteolysis, and cataract formation.
Cataract
Inhibition of fiber cell globulization and hyperglycemia-induced lens opacification by aminopeptidase inhibitor bestatin.
Cataract
Inhibition of lens epithelial cells by Fas-specific antibody activating Fas-Fas ligand system.
Cataract
Phenotypes of Recessive Pediatric Cataract in a Cohort of Children with Identified Homozygous Gene Mutations (An American Ophthalmological Society Thesis).
Cataract
Protein oxidation and loss of protease activity may lead to cataract formation in the aged lens.
Cataract
Racemization of tyrosine in the insoluble protein fraction of brunescent aging human lenses.
Cataract
Secreted leukocyte protease inhibitor is present in aqueous humours from cataracts and other eye pathologies.
Cataract
Sequence analysis of lens beta-crystallins suggests involvement of calpain in cataract formation.
cathepsin k deficiency
Cathepsin K inhibitors for osteoporosis and potential off-target effects.
cathepsin l deficiency
Contribution of cathepsin L to secretome composition and cleavage pattern of mouse embryonic fibroblasts.
cathepsin l deficiency
Epidermal differentiation: the role of proteases and their inhibitors.
Catheter-Related Infections
Impact of the functional status of saeRS on in vivo phenotypes of Staphylococcus aureus?sarA mutants.
Celiac Disease
A commensal Bifidobacterium longum strain improves gluten-related immunopathology in mice through expression of a serine protease inhibitor.
Celiac Disease
Decreased expression of protease inhibitor 9, a granzyme B inhibitor, in celiac disease: a potential mechanism in enterocyte destruction and villous atrophy.
Celiac Disease
Engineering of Kuma030: a gliadin peptidase that rapidly degrades immunogenic gliadin peptides in gastric conditions.
Central Nervous System Diseases
An optimized quantitative proteomics method establishes the cell type-resolved mouse brain secretome.
Central Nervous System Diseases
Cellular localization and enzymatic activity of cathepsin B after spinal cord injury in the rat.
Central Nervous System Diseases
Matrix metalloproteinase-9 and urokinase plasminogen activator mediate interleukin-1-induced neurotoxicity.
Central Nervous System Infections
Atherosclerosis and central adiposity in a pediatric patient with AIDS treated with HAART: autopsy findings.
Central Nervous System Neoplasms
Concentrations of insulin-like growth factor (IGF)-binding protein-3 (IGFBP-3), IGF, and IGFBP-3 protease activity in cerebrospinal fluid of children with leukemia, central nervous system tumor, or meningitis.
Cerebellar Ataxia
Loss of function of the mitochondrial peptidase PITRM1 induces proteotoxic stress and Alzheimer's disease-like pathology in human cerebral organoids.
Cerebral Amyloid Angiopathy
Immunohistochemical study of cerebral amyloid angiopathy. III. Widespread Alzheimer A4 peptide in cerebral microvessel walls colocalizes with gamma trace in patients with leukoencephalopathy.
Cerebral Hemorrhage
Bacillus anthracis Protease InhA Increases Blood-Brain Barrier Permeability and Contributes to Cerebral Hemorrhages.
Cerebral Hemorrhage
Contribution of extracellular proteolysis and microglia to intracerebral hemorrhage.
Cerebral Hemorrhage
Increased Expression of Ubiquitin-Specific Protease 4 Participates in Neuronal Apoptosis After Intracerebral Hemorrhage in Adult Rats.
Cerebral Hemorrhage
Infarct reduction in rats following intraventricular administration of either tissue plasminogen activator (tPA) or its non-protease mutant S478A-tPA.
Cerebral Hemorrhage
Matrix metalloproteinase-9 inhibition attenuates vascular endothelial growth factor-induced intracerebral hemorrhage.
Cerebral Hemorrhage
Nafamostat mesilate attenuates transient focal ischemia/reperfusion-induced brain injury via the inhibition of endoplasmic reticulum stress.
Cerebral Hemorrhage
Protease activated receptor 1 (PAR1) enhances Src-mediated tyrosine phosphorylation of NMDA receptor in intracerebral hemorrhage (ICH).
Cerebral Hemorrhage
Protease-activated receptor 1 inhibitor improves brain edema in rats with intracerebral hemorrhage.
Cerebral Hemorrhage
The expression and the role of protease nexin-1 on brain edema after intracerebral hemorrhage.
Cerebral Hemorrhage
Thrombin stimulation of guanosine 3',5'-monophosphate formation in murine neuroblastoma cells (clone N1E-115).
Cerebral Hemorrhage
Thrombin-induced delayed injury involves multiple and distinct signaling pathways in the cerebral cortex and the striatum in organotypic slice cultures.
Cerebral Infarction
Tissue plasminogen activator (tPA) deficiency exacerbates cerebrovascular fibrin deposition and brain injury in a murine stroke model: studies in tPA-deficient mice and wild-type mice on a matched genetic background.
Cerebral Infarction
Tissue plasminogen activator (tPA) increases neuronal damage after focal cerebral ischemia in wild-type and tPA-deficient mice.
Cerebral Small Vessel Diseases
A novel heterozygous HTRA1 mutation is associated with autosomal dominant hereditary cerebral small vessel disease.
Cerebrovascular Disorders
Characterization of polymorphic structure of cathepsin G gene: role in cardiovascular and cerebrovascular diseases.
Cerebrovascular Disorders
Increased tissue factor pathway inhibitor and homocysteine in Alzheimer's disease.
Cerebrovascular Disorders
PAR-1 Inhibitors: A Novel Class of Antiplatelet Agents for the Treatment of Patients with Atherothrombosis.
Cerebrovascular Disorders
Physiologic Frailty and Fragility Fracture in HIV-Infected Male Veterans.
Cervical Intraepithelial Neoplasia
Expression patterns of seprase, a membrane serine protease, in cervical carcinoma and cervical intraepithelial neoplasm.
Chagas Disease
A cysteine protease inhibitor cures chagas' disease in an immunodeficient-mouse model of infection.
Chagas Disease
A target within the target: probing cruzain's P1' site to define structural determinants for the Chagas' disease protease.
Chagas Disease
Absence of myocardial calcium-independent phospholipase A2? results in impaired PGE2 production and decreased survival in mice with acute Trypanosoma cruzi infection.
Chagas Disease
An Overview on the Therapeutics of Neglected Infectious Diseases-Leishmaniasis and Chagas Diseases.
Chagas Disease
Application of Computer-Aided Drug Repurposing in the Search of New Cruzipain Inhibitors: Discovery of Amiodarone and Bromocriptine Inhibitory Effects.
Chagas Disease
Cysteine protease isoforms from Trypanosoma cruzi, cruzipain 2 and cruzain, present different substrate preference and susceptibility to inhibitors.
Chagas Disease
Effects of a marine serine protease inhibitor on viability and morphology of Trypanosoma cruzi, the agent of Chagas disease.
Chagas Disease
Induction of autophagy increases the proteolytic activity of reservosomes during Trypanosoma cruzi metacyclogenesis.
Chagas Disease
Infestin 1R, an intestinal subtilisin inhibitor from Triatoma infestans able to impair mammalian cell invasion by Trypanosoma cruzi.
Chagas Disease
Novel compounds to combat trypanosomatid infections: a medicinal chemical perspective.
Chagas Disease
Peptide-fluoromethyl ketones arrest intracellular replication and intercellular transmission of Trypanosoma cruzi.
Chagas Disease
Self-Masked Aldehyde Inhibitors: A Novel Strategy for Inhibiting Cysteine Proteases.
Chagas Disease
Triapsin, an unusual activatable serine protease from the saliva of the hematophagous vector of Chagas' disease Triatoma infestans (Hemiptera: Reduviidae).
Chagas Disease
Trypanosoma cruzi: killing and enhanced uptake by resident peritoneal macrophages treated with alpha-2-macroglobulin.
Chagas Disease
[Cysteine-dependent protease in Trypanosoma cruzi useful for the diagnosis of Chagas disease]
Chagas Disease
[Trypanocidal effect of cysteine protease inhibitors in vitro and in vivo in experimental Chagas disease]
Charcot-Marie-Tooth Disease
Activities of some antioxidative and hexose monophosphate shunt enzymes of skeletal muscle in neuromuscular diseases.
Chediak-Higashi Syndrome
Selective inhibition of dipeptidyl peptidase I, not caspases, prevents the partial processing of procaspase-3 in CD3-activated human CD8(+) T lymphocytes.
Cheilitis
Protease inhibitor-related paronychia, ingrown toenails, desquamative cheilitis and cutaneous xerosis.
Chickenpox
Kallikrein-6-Regulated Pathways Shed Light on New Potential Targets in Varicella Zoster Virus Infection.
Chickenpox
Plasma levels of the von Willebrand factor-cleaving protease in physiological and pathological conditions in children.
Chickenpox
Studies on in vitro proteolytic sensitivity of peptides inhibiting herpes simplex virus ribonucleotide reductases lead to discovery of a stable and potent inhibitor.
Chlamydia Infections
Chlamydia Serine Protease Inhibitor, targeting HtrA, as a New Treatment for Koala Chlamydia infection.
Cholangiocarcinoma
MOC31 immunoreactivity in primary and metastatic carcinoma of the liver. Report of findings and review of other utilized markers.
Cholangiocarcinoma
Operative ubiquitin-specific protease 22 deubiquitination confers a more invasive phenotype to cholangiocarcinoma.
Cholangiocarcinoma
Serum protease inhibitors in opisthorchiasis, hepatoma, cholangiocarcinoma, and other liver diseases.
Cholangiocarcinoma
Ubiquitin-specific protease 14 expression associated with intrahepatic cholangiocarcinoma cell differentiation.
Choledochal Cyst
[Analysis of pancreatic enzymes in the bile of congenital choledochal cyst with anomalous pancreaticobiliary ductal union]
Cholelithiasis
Is ritonavir-boosted atazanavir a risk for cholelithiasis compared to other protease inhibitors?
Cholera
Alterations in Vibrio cholerae motility phenotypes correlate with changes in virulence factor expression.
Cholera
Analysis of the Vibrio pathogenicity island-encoded Mop protein suggests a pleiotropic role in the virulence of epidemic Vibrio cholerae.
Cholera
Characterization of a periplasmic thiol:disulfide interchange protein required for the functional maturation of secreted virulence factors of Vibrio cholerae.
Cholera
Characterization of alpha(s)-immunoreactive ADP-ribosylated proteins in postmortem human brain.
Cholera
DksA-HapR-RpoS axis regulates haemagglutinin protease production in Vibrio cholerae.
Cholera
Enterotoxigenicity of mature 45-kilodalton and processed 35-kilodalton forms of hemagglutinin protease purified from a cholera toxin gene-negative Vibrio cholerae non-O1, non-O139 strain.
Cholera
Evidence for the requirement of proteolysis in LH stimulated cyclic AMP production and steroidogenesis in Leydig cells.
Cholera
Expression of gangliosides as receptors at the cell surface controls infection of NCTC 2071 cells by Sendai virus.
Cholera
Expression of mucin synthesis and secretion in human tracheobronchial epithelial cells grown in culture.
Cholera
Functional characterization of the stringent response regulatory gene dksA of Vibrio cholerae and its role in modulation of virulence phenotypes.
Cholera
Histopathological changes in experimental cholera with a non toxigenic non- O1 non-O139 Vibrio cholerae strain isolated from Kolkata, India.
Cholera
Intranasal immunization with recombinant Trichinella spiralis serine protease elicits protective immunity in BALB/c mice.
Cholera
Proteomic analysis of the vibrio cholerae type II secretome reveals new proteins including three related serine proteases.
Cholera
Quorum sensing and a global regulator TsrA control expression of type VI secretion and virulence in Vibrio cholerae.
Cholera
Rugose atypical Vibrio cholerae O1 El Tor responsible for 2009 cholera outbreak in India.
Cholera
[TYPING OF VIBRIO CHOLERAE NON O1/NON O139 STRAINS, ISOLATED IN ROSTOV REGION IN 2014].
Cholestasis
Effect of bile duct obstruction on pancreatic enzyme secretion and intestinal proteolytic enzyme activity in the rat.
Cholestasis
Induction of the mitochondrial permeability transition as a mechanism of liver injury during cholestasis: a potential role for mitochondrial proteases.
Cholestasis
Risk factors for acute liver enzyme abnormalities in HIV-hepatitis B virus-coinfected patients on antiretroviral therapy.
Cholestasis
The Coagulation System Contributes to {alpha}V{beta}6 Integrin Expression and Liver Fibrosis Induced by Cholestasis.
Cholestasis
[Effect of the protease inhibitor contrical on liver and serum proteolytic enzyme activity in experimental cholestasis]
Cholesteatoma
Expression of secretory leukocyte protease inhibitor in middle ear cholesteatoma.
Cholesteatoma, Middle Ear
Expression of secretory leukocyte protease inhibitor in middle ear cholesteatoma.
Chondrosarcoma
Collagenase-3 (MMP-13) expression in chondrosarcoma cells and its regulation by basic fibroblast growth factor.
Chondrosarcoma
Kunitz-type protease inhibitor bikunin disrupts phorbol ester-induced oligomerization of CD44 variant isoforms containing epitope v9 and subsequently suppresses expression of urokinase-type plasminogen activator in human chondrosarcoma cells.
Chorioamnionitis
Nafamostat mesilate, a serine protease inhibitor, suppresses lipopolysaccharide-induced nitric oxide synthesis and apoptosis in cultured human trophoblasts.
Chorioamnionitis
Overexpression of histamine H(1)-receptor by human amniotic epithelial cells in chorioamnionitis correlates with augmented production of secretory leukocyte protease inhibitor.
Chorioamnionitis
Protease production by microorganisms associated with reproductive tract infection.
Chorioamnionitis
Ureaplasma Infection Mediated Release of Matrix Metalloproteinase-9 and PGP - a Novel Mechanism of Preterm Rupture of Membranes and Chorioamnionitis.
Choriocarcinoma
Leukemia inhibitory factor triggers activation of signal transducer and activator of transcription 3, proliferation, invasiveness, and altered protease expression in choriocarcinoma cells.
Chronic Periodontitis
Analysis of in situ protease activity in chronic adult periodontitis patients: expression of activated MMP-2 and a 40 kDa serine protease.
Chronic Periodontitis
Arginine-specific gingipains from Porphyromonas gingivalis deprive protective functions of secretory leucocyte protease inhibitor in periodontal tissue.
Chronic Periodontitis
Expression of protease activated receptor-1 in chronic periodontitis.
Chronic Periodontitis
Human ?-defensin 2 and protease activated receptor-2 expression in patients with chronic periodontitis.
Chronic Periodontitis
Inhibition of C3 and IgG proteolysis enhances phagocytosis of Porphyromonas gingivalis.
Chronic Periodontitis
Proteolytic inactivation of LL-37 by karilysin, a novel virulence mechanism of Tannerella forsythia.
Chronic Periodontitis
Secretory leukocyte protease inhibitor and its potential interactions with elastase and cathepsin B in gingival crevicular fluid and saliva from patients with chronic periodontitis.
Chronic Periodontitis
The short-term effectiveness of non-surgical treatment in reducing protease activity in gingival crevicular fluid from chronic periodontitis patients.
Chronic Periodontitis
Towards the definition of a Peptidome Signature and Protease Profile in Chronic Periodontitis.
Chronic Periodontitis
Within-mouth correlations for indicators of the host response in gingival crevicular fluid.
Chronic Urticaria
Refractory chronic urticaria treated effectively with the protease inhibitors, nafamostat mesilate and camostat mesilate.
Chronic Urticaria
Serum alpha 1-protease inhibitor levels in patients with chronic idiopathic urticaria.
Churg-Strauss Syndrome
Antibodies to selected minor target antigens in patients with anti-neutrophil cytoplasmic antibodies (ANCA).
Churg-Strauss Syndrome
Detection of autoantibodies against myeloid lysosomal enzymes: a useful adjunct to classification of patients with biopsy-proven necrotizing arteritis.
Churg-Strauss Syndrome
Distinct differences in autoantigen specificity of anti-neutrophil cytoplasm antibodies in systemic vasculitides and other inflammatory diseases.
Classical Swine Fever
Autocatalytic Cleavage within Classical Swine Fever Virus NS3 Leads to a Functional Separation of Protease and Helicase.
Classical Swine Fever
Characterization of classical swine fever virus (CSFV) nonstructural protein 3 (NS3) helicase activity and its modulation by CSFV RNA-dependent RNA polymerase.
Classical Swine Fever
Hax-1: a regulator of calcium signaling and apoptosis progression with multiple roles in human disease.
Classical Swine Fever
Loss of interferon regulatory factor 3 in cells infected with classical swine fever virus involves the N-terminal protease, Npro.
Classical Swine Fever
The classical swine fever virus N-terminal protease N(pro) binds to cellular HAX-1.
Classical Swine Fever
The influence of protease inhibitors of the organism, especially bovine aprotinin, on the production of virulent hog cholera virus in tissue cultures.
Classical Swine Fever
The uncoupling of protease trans-cleavage and helicase activities in the pestivirus NS3.
Clostridium Infections
Immunization of hamsters against Clostridium difficile infection using the Cwp84 protease as an antigen.
Clostridium Infections
Location and stoichiometry of the protease CspB and the cortex-lytic enzyme SleC in Clostridium perfringens spores.
coagulation factor ixa deficiency
A Candidate Activation Pathway for Coagulation Factor VII.
coagulation factor viia deficiency
Detection of two missense mutations and characterization of a repeat polymorphism in the factor VII gene (F7).
coagulation factor xia deficiency
Polyphosphate is a cofactor for the activation of factor XI by thrombin.
coagulation factor xiia deficiency
Polyphosphate is a cofactor for the activation of factor XI by thrombin.
Coccidioidomycosis
Coccidioidomycosis in human immunodeficiency virus-infected persons in Arizona, 1994-1997: incidence, risk factors, and prevention.
Coccidiosis
Dietary protease can alleviate negative effects of a coccidiosis infection on production performance in broiler chickens
Cockayne Syndrome
Insusceptibility of Cockayne syndrome-derived lymphocytes to plasminogen activator-like protease induction by ultraviolet rays and its abolition by interferon.
Cockayne Syndrome
Involvement of antipain-sensitive protease activity in the interferon-beta-induced UV-refractoriness of Cockayne syndrome fibroblasts.
Cockayne Syndrome
Reversal of mitochondrial defects with CSB-dependent serine protease inhibitors in patient cells of the progeroid Cockayne syndrome.
Coinfection
Accelerated elimination of N. brasiliensis from the small intestine after auto-anti-IgE induction.
Coinfection
Association between exposure to nevirapine and reduced liver fibrosis progression in patients with HIV and hepatitis C virus coinfection.
Coinfection
Boceprevir and Antiretroviral Pharmacokinetic Interactions in HIV/HCV Co-infected Persons: AIDS Clinical Trials Group Study A5309s.
Coinfection
Cervicovaginal Shedding of HIV Type 1 Is Related to Genital Tract Inflammation Independent of Changes in Vaginal Microbiota.
Coinfection
Clinical and Emotional Factors Related to Erectile Dysfunction in HIV-Infected Men.
Coinfection
Detection of free and immune-complexed serine protease and its antibody in TB patients with and without HIV co-infection.
Coinfection
Effect of HIV/HCV Co-Infection on the Protease Evolution of HIV-1B: A Pilot Study in a Pediatric Population.
Coinfection
Elevated plasma concentrations of protease inhibitors and nonnucleoside reverse transcriptase inhibitors in patients coinfected with human immunodeficiency virus and hepatitis B or C: case series and literature review.
Coinfection
Evaluation of Statin Eligibility, Prescribing Practices, and Therapeutic Responses Using ATP III, ACC/AHA, and NLA Dyslipidemia Treatment Guidelines in a Large Urban Cohort of HIV-Infected Outpatients.
Coinfection
Frequency and severity of potential drug interactions in a cohort of HIV-infected patients Identified through a Multidisciplinary team.
Coinfection
Genital Herpes Simplex Virus Type 2 Infection in Humanized HIV-Transgenic Mice Triggers HIV Shedding and Is Associated With Greater Neurological Disease.
Coinfection
Glecaprevir/pibrentasvir-associated acute liver injury in non-cirrhotic, chronic HCV infection without HBV co-infection.
Coinfection
Hepatitis B and C virus co-infection and the risk for hepatotoxicity of highly active antiretroviral therapy in HIV-1 infection.
Coinfection
HIV Reverse Transcriptase and Protease Genes Variability Can Be a Biomarker Associated with HIV and Hepatitis B or C Coinfection.
Coinfection
HIV-1 acquires resistance to two classes of antiviral drugs through homologous recombination.
Coinfection
HIV-HCV co-infection facing HCV protease inhibitor licensing: implications for clinicians.
Coinfection
Impact of a basement membrane-degrading protease on dissemination and secondary infection of Autographa californica multiple nucleopolyhedrovirus in Heliothis virescens (Fabricus).
Coinfection
Impact of interferon-ribavirin treatment on hepatitis C virus (HCV) protease quasispecies diversity in HIV- and HCV-coinfected patients.
Coinfection
Impact of tuberculosis cotreatment on viral suppression rates among HIV-positive children initiating HAART.
Coinfection
Increased levels of immune activation in the genital tract of healthy young women from sub-Saharan Africa.
Coinfection
Influence of ABCC2 and ABCC4 polymorphisms on tenofovir plasma concentrations in Thai HIV-infected patients.
Coinfection
Influence of drug transport proteins on the pharmacokinetics and drug interactions of HIV protease inhibitors.
Coinfection
Metabolic changes associated with antiretroviral therapy in HIV-positive patients.
Coinfection
Metabolic Syndrome in French HIV-Infected Patients: Prevalence and Predictive Factors After 3 Years of Antiretroviral Therapy.
Coinfection
Naturally occurring hepatitis C virus protease inhibitors resistance-associated mutations among chronic hepatitis C genotype 1b patients with or without HIV co-infection.
Coinfection
Phase 3 trial of first generation protease inhibitor therapy for hepatitis C virus/human immunodeficiency virus coinfection.
Coinfection
Predicting the magnitude of short-term CD4+ T-cell recovery in HIV-infected patients during first-line highly active antiretroviral therapy.
Coinfection
Predictive factors of lopinavir/ritonavir discontinuation for drug-related toxicity: results from a cohort of 416 multi-experienced HIV-infected individuals.
Coinfection
Prevalence and factors associated with HIV-1 multi-drug resistance over the past two decades in the Italian ARCA database.
Coinfection
Prevalence and factors involved in discordant responses to highly active antiretroviral treatment in a closely followed cohort of treatment-naïve HIV-infected patients.
Coinfection
Production and characterization of simian--human immunodeficiency virus-like particles.
Coinfection
Prospective, Open-Label Comparative Study of Liver Toxicity in an Unselected Population of HIV-Infected Patients Treated for the First Time with Efavirenz or Nevirapine.
Coinfection
Rates and Correlates of Incident Type 2 Diabetes Mellitus Among Persons Living With HIV-1 Infection.
Coinfection
Risk factors for sexual and erectile dysfunction in HIV-infected men: the role of protease inhibitors.
Coinfection
Risk of Liver Enzyme Elevation during Treatment with Ritonavir-boosted Protease Inhibitors among HIV-monoinfected and HIV/HCV Coinfected Patients.
Coinfection
Streptococcus oralis and Candida albicans Synergistically Activate ?-Calpain to Degrade E-cadherin From Oral Epithelial Junctions.
Coinfection
Stronger activity of human immunodeficiency virus type 1 protease inhibitors against clinical isolates of Plasmodium vivax than against those of P. falciparum.
Coinfection
The protease and gag gene products of the human immunodeficiency virus: authentic cleavage and post-translational modification in an insect cell expression system.
Coinfection
The utility of nucleos(t)ide-only regimens in the treatment of Mycobacterium tuberculosis-HIV-1 coinfection.
Coinfection
Treatment with protease inhibitors and coinfection with hepatitis C virus are independent predictors of preterm delivery in HIV-infected pregnant women.
Coinfection
Use of first-generation hcv protease inhibitors in patients coinfected by hiv and hcv genotype 1.
Coinfection
[Effect of Staphylococcal proteinase on adherence of Candida albicans to mucous membrane cells in vitro]
Coinfection
[The pathogenetic therapy of acute respiratory diseases by aprotinin inhalations]
Colic
Case of a bleeding pseudoaneurysm of the middle colic artery complicating acute pancreatitis.
Colitis
Application of a chemical probe to detect neutrophil elastase activation during inflammatory bowel disease.
Colitis
Bowman-Birk inhibitor concentrate: a novel therapeutic agent for patients with active ulcerative colitis.
Colitis
Core 1- and 3-derived O-glycans collectively maintain the colonic mucus barrier and protect against spontaneous colitis in mice.
Colitis
Effect of recombinant serine protease from adult stage of Trichinella spiralis on TNBS-induced experimental colitis in mice.
Colitis
Effect of recombinant serine protease from newborn larval stage of Trichinella spiralis on 2,4,6-trinitrobenzene sulfonic acid-induced experimental colitis in mice.
Colitis
Effect of T. spiralis Serine protease inhibitors on TNBS-induced experimental colitis mediated by Macrophages.
Colitis
Effect of two recombinant Trichinella spiralis serine protease inhibitors on TNBS-induced experimental colitis of mice.
Colitis
Endothelial MT1-MMP targeting limits intussusceptive angiogenesis and colitis via TSP1/nitric oxide axis.
Colitis
Enteric bacterial proteases in inflammatory bowel disease- pathophysiology and clinical implications.
Colitis
Fluorescent diphenylphosphonate-based probes for detection of serine protease activity during inflammation.
Colitis
Hookworm excretory/secretory products induce interleukin-4 (IL-4)+ IL-10+ CD4+ T cell responses and suppress pathology in a mouse model of colitis.
Colitis
Increased Pancreatic Protease Activity in Response to Antibiotics Impairs Gut Barrier and Triggers Colitis.
Colitis
Inhibition of HtrA2 alleviated dextran sulfate sodium (DSS)-induced colitis by preventing necroptosis of intestinal epithelial cells.
Colitis
Malt1 inactivation attenuates experimental colitis through the regulation of Th17 and Th1/17 cells.
Colitis
Modifying the protease, antiprotease pattern by elafin overexpression protects mice from colitis.
Colitis
Outcome of AIDS-associated cytomegalovirus colitis in the era of potent antiretroviral therapy.
Colitis
Participation of mast cells in colitis inflammation induced by dextran sulfate sodium.
Colitis
Prophylactic and curative anti-ulcerative colitis activity and the possible mechanisms of action of some desert plants.
Colitis
Protease inhibitors in plasma and faecal extracts from patients with active inflammatory bowel disease.
Colitis
Protease inhibitory activity of secretory leukocyte protease inhibitor ameliorates murine experimental colitis by protecting the intestinal epithelial barrier.
Colitis
Role of a class 1 serine protease autotransporter in the pathogenesis of Citrobacter rodentium colitis.
Colitis
Serine protease inhibitors protect better than IL-10 and TGF-? anti-inflammatory cytokines against mouse colitis when delivered by recombinant lactococci.
Colitis
The Effect of a Novel Serine Protease Inhibitor on Inflammation and Intestinal Permeability in a Murine Colitis Transfer Model.
Colitis
Unconjugated bilirubin ameliorates the inflammation and digestive protease increase in TNBS-induced colitis.
Colitis
[Component analysis of excretory/secretory protein from Trichinella spiralis adult worm].
Colitis
[Role of bacterial toxins in pathogenesis of hemolytic-uremic syndrome, caused by enterohemorrhagic Escherichia]
Colitis, Ulcerative
A low dose of fermented soy germ alleviates gut barrier injury, hyperalgesia and faecal protease activity in a rat model of inflammatory bowel disease.
Colitis, Ulcerative
Clostridium ramosum, an IgA protease-producing species and its ecology in the human intestinal tract.
Colitis, Ulcerative
Correlation of thrombotic thrombocytopenic purpura disease activity with von Willibrand factor-cleaving protease level in ulcerative colitis.
Colitis, Ulcerative
Inflammatory cytokines down-regulate the barrier-protective prostasin-matriptase proteolytic cascade early in experimental colitis.
Colitis, Ulcerative
Protease activity in a hapten-induced model of ulcerative colitis in rats.
Colitis, Ulcerative
Protease signaling through protease activated receptor 1 mediate nerve activation by mucosal supernatants from irritable bowel syndrome but not from ulcerative colitis patients.
Colitis, Ulcerative
Release of interleukin-1 receptor antagonist by combining a leukocyte adsorption carrier with ulinastatin.
Colitis, Ulcerative
The protease inhibitor, Bowman-Birk Inhibitor, suppresses experimental autoimmune encephalomyelitis: a potential oral therapy for multiple sclerosis.
Colitis, Ulcerative
Treatment of ulcerative colitis with camostat mesilate, a serine protease inhibitor.
Colitis, Ulcerative
Tumor marker utility and prognostic relevance of cathepsin B, cathepsin L, urokinase-type plasminogen activator, plasminogen activator inhibitor type-1, CEA and CA 19-9 in colorectal cancer.
Colitis, Ulcerative
[Serine protease inhibitors in plasma of patients with ulcerative colitis]
Colonic Neoplasms
?-lactoglobulin-pectin Nanoparticle-based Oral Drug Delivery System for Potential Treatment of Colon Cancer.
Colonic Neoplasms
A bacterial protease depletes c-MYC and increases survival in mouse models of bladder and colon cancer.
Colonic Neoplasms
A Clinical Wide-Field Fluorescence Endoscopic Device for Molecular Imaging Demonstrating Cathepsin Protease Activity in Colon Cancer.
Colonic Neoplasms
A three-dimensional and temporo-spatial model to study invasiveness of cancer cells by heregulin and prostaglandin E2.
Colonic Neoplasms
Activated protease receptor-2 induces GATA6 expression to promote survival in irradiated colon cancer cells.
Colonic Neoplasms
Antitumor effects of Nafamostat mesilate on head and neck squamous cell carcinoma.
Colonic Neoplasms
Antitumoral Efficacy of the Protease Inhibitor Gabexate Mesilate in Colon Cancer Cells Harbouring KRAS, BRAF and PIK3CA Mutations.
Colonic Neoplasms
As an independent prognostic factor, USP6 promotes the invasion and metastasis of colon cancer.
Colonic Neoplasms
Cathepsin B in the growth of colorectal cancer: suppressive effect of leupeptin on the growth of DMH-induced rat colon neoplasm.
Colonic Neoplasms
Co-localization of Protein Z, Protein Z-Dependent protease inhibitor and coagulation factor X in human colon cancer tissue: implications for coagulation regulation on tumor cells.
Colonic Neoplasms
Colonic adenocarcinomas: near-infrared microcatheter imaging of smart probes for early detection--study in mice.
Colonic Neoplasms
Discovery of novel 2-hydroxydiarylamide derivatives as TMPRSS4 inhibitors.
Colonic Neoplasms
Downregulation of survivin expression by induction of the effector cell protease receptor-1 reduces tumor growth potential and results in an increased sensitivity to anticancer agents in human colon cancer.
Colonic Neoplasms
Endogenous expression of proteases in colon cancer cells facilitate influenza A viruses mediated oncolysis.
Colonic Neoplasms
Extra- and Intracellular Imaging of human Matrix Metalloprotease 11 (hMMP-11) with a Cell-Penetrating FRET-Substrate.
Colonic Neoplasms
Hepatocyte growth factor induces colonic cancer cell invasiveness via enhanced motility and protease overproduction. Evidence for PI3 kinase and PKC involvement.
Colonic Neoplasms
Hybrid Small Animal Imaging System Combining Magnetic Resonance Imaging With Fluorescence Tomography Using Single Photon Avalanche Diode Detectors.
Colonic Neoplasms
Interleukin-6 increases expression of serine protease inhibitor Kazal type 1 through STAT3 in colorectal adenocarcinoma.
Colonic Neoplasms
Intestinal human colon adenocarcinoma cell line LS180 is an excellent model to study pregnane X receptor, but not constitutive androstane receptor, mediated CYP3A4 and multidrug resistance transporter 1 induction: studies with anti-human immunodeficiency virus protease inhibitors.
Colonic Neoplasms
Kallikrein 6 protease advances colon tumorigenesis via induction of the high mobility group A2 protein.
Colonic Neoplasms
Legume seeds and colorectal cancer revisited: Protease inhibitors reduce MMP-9 activity and colon cancer cell migration.
Colonic Neoplasms
LonP1 Differently Modulates Mitochondrial Function and Bioenergetics of Primary Versus Metastatic Colon Cancer Cells.
Colonic Neoplasms
Molecular cloning of a novel trypsin-like serine protease (neurosin) preferentially expressed in brain.
Colonic Neoplasms
Point: From animal models to prevention of colon cancer. Systematic review of chemoprevention in min mice and choice of the model system.
Colonic Neoplasms
Proenzyme to urokinase-type plasminogen activator in human colon cancer: in vitro inhibition by monocyte minactivin after proteolytic activation.
Colonic Neoplasms
Protease inhibitors interfere with the necessary factors of carcinogenesis.
Colonic Neoplasms
Protease-Responsive Targeted Delivery of Doxorubicin from Bilirubin-BSA-Capped Mesoporous Silica Nanoparticles against Colon Cancer.
Colonic Neoplasms
Release of cell surface proteoglycans from differentiating colon cells proceeds by cleavage of lipophilic anchor peptides.
Colonic Neoplasms
Requirement of the enzymatic and signaling activities of plasmin for phorbol-ester-induced scattering of colon cancer cells.
Colonic Neoplasms
Serine protease inhibitor Kazal type 1 (SPINK1) as a prognostic marker in stage IV colon cancer patients receiving cetuximab based targeted therapy.
Colonic Neoplasms
Silencing of mitochondrial Lon protease deeply impairs mitochondrial proteome and function in colon cancer cells.
Colonic Neoplasms
The anti-proliferative effect of TI1B, a major Bowman-Birk isoinhibitor from pea (Pisum sativum L.), on HT29 colon cancer cells is mediated through protease inhibition.
Colonic Neoplasms
The protective role of the Bowman-Birk protease inhibitor in soybean lunasin digestion: the effect of released peptides on colon cancer growth.
Colonic Neoplasms
Thrombin-dependent modulation of ?1-integrin-mediated signaling up-regulates prolidase and HIF-1? through p-FAK in colorectal cancer cells.
Colonic Neoplasms
Transmembrane Protease TMPRSS4 Promotes the Formation and Development of Mismatch Repair Deficient Colon Cancer Liver Metastasis.
Colonic Neoplasms
Ubiquitin-Specific Protease 21 Promotes Colorectal Cancer Metastasis by Acting as a Fra-1 Deubiquitinase.
Colonic Neoplasms
Up-regulation and clinical significance of serine protease kallikrein 6 in colon cancer.
Colonic Neoplasms
USP46 Inhibits Cell Proliferation in Lung Cancer through PHLPP1/AKT Pathway.
Colonic Neoplasms
[Expression and clinical significance of secretory leucocyte protease inhibitor in colon carcinoma].
Colorectal Neoplasms
3,3'-diindolylmethane downregulates cyclin D1 through triggering endoplasmic reticulum stress in colorectal cancer cells.
Colorectal Neoplasms
A lack of evidence for down-modulation of CD3 zeta expression in colorectal carcinoma and pregnancy using multiple detection methods.
Colorectal Neoplasms
A novel serine protease SNC19 associated with human colorectal cancer.
Colorectal Neoplasms
A Selective Inhibitor of Ubiquitin-Specific Protease 4 Suppresses Colorectal Cancer Progression by Regulating ?-Catenin Signaling.
Colorectal Neoplasms
Activation of human meprin-alpha in a cell culture model of colorectal cancer is triggered by the plasminogen-activating system.
Colorectal Neoplasms
Anti-cancer activity of the novel 2-hydroxydiarylamide derivatives IMD-0354 and KRT1853 through suppression of cancer cell invasion, proliferation, and survival mediated by TMPRSS4.
Colorectal Neoplasms
ATP-dependent Lon protease controls tumor bioenergetics by reprogramming mitochondrial activity.
Colorectal Neoplasms
Computational analysis of nuclear factor-?B and resveratrol in colorectal cancer.
Colorectal Neoplasms
Cysteine peptidase and its inhibitor activity levels and vitamin E concentration in normal human serum and colorectal carcinomas.
Colorectal Neoplasms
Cysteine proteinase inhibitors stefin A, stefin B, and cystatin C in sera from patients with colorectal cancer: relation to prognosis.
Colorectal Neoplasms
Enhanced activity of meprin-?, a pro-migratory and pro-angiogenic protease, in colorectal cancer.
Colorectal Neoplasms
Estrogen and progesterone binding proteins in human colorectal cancer. A preliminary characterization of estradiol receptor.
Colorectal Neoplasms
Expression of p16 in lymph node metastases of adjuvantly treated stage III colorectal cancer patients identifies poor prognostic subgroups: a retrospective analysis of biomarkers in matched primary tumor and lymph node metastases.
Colorectal Neoplasms
Expression of protease activated receptor-2 in human colorectal cancer and its association with tumor progression.
Colorectal Neoplasms
Expression of secretory leukocyte protease inhibitor detected by immunohistochemistry correlating with prognosis and metastasis in colorectal cancer.
Colorectal Neoplasms
Expression of the immune modulator secretory leukocyte protease inhibitor (SLPI) in colorectal cancer liver metastases and matched primary tumors is associated with a poorer prognosis.
Colorectal Neoplasms
Functional protease profiling with reporter peptides in serum specimens of colorectal cancer patients: demonstration of its routine diagnostic applicability.
Colorectal Neoplasms
Gelsolin-Cu/ZnSOD interaction alters intracellular reactive oxygen species levels to promote cancer cell invasion.
Colorectal Neoplasms
High expression of testes-specific protease 50 is associated with poor prognosis in colorectal carcinoma.
Colorectal Neoplasms
Hypoxia induces epithelial-mesenchymal transition in colorectal cancer cells through ubiquitin-specific protease 47-mediated stabilization of Snail: A potential role of Sox9.
Colorectal Neoplasms
Identification of novel tumor suppressor proteases by degradome profiling of colorectal carcinomas.
Colorectal Neoplasms
Immunohistochemical analysis and prognostic value of cathepsin D determination in laryngeal squamous cell carcinoma.
Colorectal Neoplasms
Increase in ceramide level alters the lysosomal targeting of cathepsin D prior to onset of apoptosis in HT-29 colon cancer cells.
Colorectal Neoplasms
Increased expression of seprase, a membrane-type serine protease, is associated with lymph node metastasis in human colorectal cancer.
Colorectal Neoplasms
Increased expression of ubiquitin-specific protease 22 can promote cancer progression and predict therapy failure in human colorectal cancer.
Colorectal Neoplasms
Induction of caspase-3 protease activity and apoptosis by butyrate and trichostatin A (inhibitors of histone deacetylase): dependence on protein synthesis and synergy with a mitochondrial/cytochrome c-dependent pathway.
Colorectal Neoplasms
Inhibition of TMPRSS4 mediated epithelial-mesenchymal transition is critically involved in antimetastatic effect of melatonin in colorectal cancers.
Colorectal Neoplasms
Inhibition of Ubiquitin Specific Protease 1 Sensitizes Colorectal Cancer Cells to DNA-Damaging Chemotherapeutics.
Colorectal Neoplasms
Inverse relation between levels of p27(Kip1) and of its ubiquitin ligase subunit Skp2 in colorectal carcinomas.
Colorectal Neoplasms
Knock-down of ubiquitin-specific protease 22 by micro-RNA interference inhibits colorectal cancer growth.
Colorectal Neoplasms
Legume seeds and colorectal cancer revisited: Protease inhibitors reduce MMP-9 activity and colon cancer cell migration.
Colorectal Neoplasms
LonP1 Differently Modulates Mitochondrial Function and Bioenergetics of Primary Versus Metastatic Colon Cancer Cells.
Colorectal Neoplasms
MMP-14 Is Expressed in Preeclamptic Placentas and Mediates Release of Soluble Endoglin.
Colorectal Neoplasms
Nuclear maspin expression as a predictive marker for fluorouracil treatment response in colon cancer.
Colorectal Neoplasms
Nuclear maspin expression correlates with the CpG island methylator phenotype and tumor aggressiveness in colorectal cancer.
Colorectal Neoplasms
Nuclear Maspin expression is associated with response to adjuvant 5-fluorouracil based chemotherapy in patients with stage III colon cancer.
Colorectal Neoplasms
OMA1 reprograms metabolism under hypoxia to promote colorectal cancer development.
Colorectal Neoplasms
Phase II Trial of Single Agent Val-boroPro (Talabostat) Inhibiting Fibroblast Activation Protein in Patients with Metastatic Colorectal Cancer.
Colorectal Neoplasms
Photoactivated Spatiotemporally-Responsive Nanosensors of in Vivo Protease Activity.
Colorectal Neoplasms
Protease activated receptor 2 mediates tryptase-induced cell migration through MYO10 in colorectal cancer.
Colorectal Neoplasms
Protease activated receptor 2 signaling promotes self-renewal and metastasis in colorectal cancer through ?-catenin and periostin.
Colorectal Neoplasms
RAS specific protease induces irreversible growth arrest via p27 in several KRAS mutant colorectal cancer cell lines.
Colorectal Neoplasms
Rhomboid domain containing 1 promotes colorectal cancer growth through activation of the EGFR signalling pathway.
Colorectal Neoplasms
Secretion of protease nexin-II/amyloid beta protein precursor by human colorectal carcinoma cells and its modulation by cytokines/growth factors and proteinase inhibitors.
Colorectal Neoplasms
Serine Protease Inhibitor Kazal Type 1 (SPINK1) Promotes Proliferation of Colorectal Cancer Through the Epidermal Growth Factor as a Prognostic Marker.
Colorectal Neoplasms
Serine protease modulation of Dependence Receptors and EMT protein expression.
Colorectal Neoplasms
Small Molecule Inhibition of the Ubiquitin-specific Protease USP2 Accelerates cyclin D1 Degradation and Leads to Cell Cycle Arrest in Colorectal Cancer and Mantle Cell Lymphoma Models.
Colorectal Neoplasms
Substrate optimization and clinical validation of reporter peptides for MS-based protease profiling in serum specimens: a new approach for diagnosis of malignant disease.
Colorectal Neoplasms
Surface ultrastructure, protein profile and zymography of Blastocystis species isolated from patients with colorectal carcinoma.
Colorectal Neoplasms
Systematic analysis of proteins from different signaling pathways in the tumor center and the invasive front of colorectal cancer.
Colorectal Neoplasms
Systematic assessment of protein phenotypes characterizing high-grade tumour budding in mismatch repair-proficient colorectal cancer.
Colorectal Neoplasms
Targeting secretory leukocyte protease inhibitor (SLPI) inhibits colorectal cancer cell growth, migration and invasion via downregulation of AKT.
Colorectal Neoplasms
Testes-specific protease 50 as an independent risk factor for poor prognosis in patients with non-small cell lung cancer.
Colorectal Neoplasms
Transmembrane Protease TMPRSS4 Promotes the Formation and Development of Mismatch Repair Deficient Colon Cancer Liver Metastasis.
Colorectal Neoplasms
Tribulus terrestris fruit extract inhibits autophagic flux to diminish cell proliferation and metastatic characteristics of oral cancer cells.
Colorectal Neoplasms
Tumor marker utility and prognostic relevance of cathepsin B, cathepsin L, urokinase-type plasminogen activator, plasminogen activator inhibitor type-1, CEA and CA 19-9 in colorectal cancer.
Colorectal Neoplasms
Ubiquitin Specific Protease 29 Functions as an Oncogene Promoting Tumorigenesis in Colorectal Carcinoma.
Colorectal Neoplasms
Ubiquitin specific protease 4 positively regulates the WNT/?-catenin signaling in colorectal cancer.
Colorectal Neoplasms
Ubiquitin-specific protease 14 expression in colorectal cancer is associated with liver and lymph node metastases.
Colorectal Neoplasms
Ubiquitin-Specific Protease 21 Promotes Colorectal Cancer Metastasis by Acting as a Fra-1 Deubiquitinase.
Colorectal Neoplasms
Urokinase-type plasminogen activator in colorectal cancer: relationship with clinicopathological features and patient outcome.
Colorectal Neoplasms
Urokinase-type plasminogen activator is a marker of aggressive phenotype and an independent prognostic factor in mismatch repair-proficient colorectal cancer.
Colorectal Neoplasms
USP11 facilitates colorectal cancer proliferation and metastasis by regulating IGF2BP3 stability.
Colorectal Neoplasms
USP22 Suppresses SPARC Expression in Acute Colitis and Inflammation-Associated Colorectal Cancer.
Colorectal Neoplasms
USP38 regulates the stemness and chemoresistance of human colorectal cancer via regulation of HDAC3.
Colorectal Neoplasms
Zebrafish modeling reveals that SPINT1 regulates the aggressiveness of skin cutaneous melanoma and its crosstalk with tumor immune microenvironment.
Colorectal Neoplasms
[The role of cathepsins and the plasminogen activator/inhibitor system in colorectal cancer]
Coma
Dosing Recommendations for Quetiapine When Coadministered With HIV Protease Inhibitors.
Coma
Expression and Characterization of the Peptidase Domain of Streptococcus pneumoniae ComA, a Bifunctional ATP-binding Cassette Transporter Involved in Quorum Sensing Pathway.
Common Cold
Good and bad molecular fingerprints for human rhinovirus 3C protease inhibition: identification, validation, and application in designing of new inhibitors through Monte Carlo-based QSAR study.
Common Cold
Protease Inhibitors: Candidate Drugs to Inhibit Severe Acute Respiratory Syndrome Coronavirus 2 Replication.
Common Cold
Proteolytic activity and serum protease inhibitors in nasal secretions from adult patients with common colds.
Common Cold
Secretory leukocyte protease inhibitor in normal, allergic and virus induced nasal secretions.
Common Cold
Structure-activity relationships of heteroaromatic esters as human rhinovirus 3C protease inhibitors.
Communicable Diseases
'On-the-fly' optical encoding of combinatorial peptide libraries for profiling of protease specificity.
Communicable Diseases
A bacterial protease inhibitor protects antigens delivered in oral vaccines from digestion while triggering specific mucosal immune responses.
Communicable Diseases
A processive rotary mechanism couples substrate unfolding and proteolysis in the ClpXP degradation machinery.
Communicable Diseases
Activatable Carbocyanine Dimers for Photoacoustic and Fluorescent Detection of Protease Activity.
Communicable Diseases
Bacterial serine protease HtrA as a promising new target for antimicrobial therapy?
Communicable Diseases
Changes in circulation of B and non-B HIV strains: spotlight on a reference centre for infectious diseases in Northern Italy.
Communicable Diseases
Eruptive cheilitis: a new adverse effect in reactive HIV-positive patients subjected to high activity antiretroviral therapy (HAART). Presentation of six clinical cases.
Communicable Diseases
HIV-1 subtype characteristics of infected persons living in southwestern Greece.
Communicable Diseases
Pathogen proteases and host protease inhibitors in molluscan infectious diseases.
Communicable Diseases
Protease Inhibition-An Established Strategy to Combat Infectious Diseases.
Communicable Diseases
Self-Masked Aldehyde Inhibitors: A Novel Strategy for Inhibiting Cysteine Proteases.
Communicable Diseases
Simultaneous dermatophytosis and keratomycosis caused by Trichophyton interdigitale infection: a case report and literature review.
Communicable Diseases
SmSP2: A serine protease secreted by the blood fluke pathogen Schistosoma mansoni with anti-hemostatic properties.
Communicable Diseases
The application of terminomics for the identification of protein start sites and proteoforms in bacteria.
Communicable Diseases
[Impact of protease inhibitors on hospitalization in an Infectious Disease Unit]
Communicable Diseases
[Usefulness of a protease inhibitor (urinastatin) in ARDS with infectious diseases]
Complex Regional Pain Syndromes
Labeled substance P as a neuropeptide reporter substance for enzyme activity.
Complex Regional Pain Syndromes
Reduced serum protease activity in Complex Regional Pain Syndrome: The impact of angiotensin-converting enzyme and carboxypeptidases.
Complex Regional Pain Syndromes
The serum protease network - one key to understand Complex Regional Pain Syndrome pathophysiology.
Condylomata Acuminata
A pharmacokinetic evaluation of 14C-labeled afovirsen sodium in patients with genital warts.
Confusion
A perspective on the measurement of ADAMTS13 in thrombotic thrombocytopaenic purpura.
Congenital Abnormalities
A complex of serine protease genes expressed preferentially in cytotoxic T-lymphocytes is closely linked to the T-cell receptor alpha- and delta-chain genes on mouse chromosome 14.
Congenital Abnormalities
Antiretroviral Drugs for Preventing Mother-to-Child Transmission of HIV: A Review of Potential Effects on HIV-Exposed but Uninfected Children.
Congenital Abnormalities
Birth defects among a cohort of infants born to HIV-infected women on antiretroviral medication.
Congenital Abnormalities
Birth defects in a national cohort of pregnant women with HIV infection in Italy, 2001-2011.
Conjunctivitis
Genetic features of Pseudomonas aeruginosa isolates associated with eye infections referred to Farabi Hospital, Tehran, Iran.
Conjunctivitis
[Comparative characteristics of the antibioticograms and biological properties of the staphylococci isolated from patients with various eye diseases]
Conjunctivitis, Allergic
Increased conjunctival expression of protease activated receptor 2 (PAR-2) in seasonal allergic conjunctivitis: a role for abnormal conjunctival epithelial permeability in disease pathogenesis?
Conjunctivitis, Allergic
SLPI prevents cytokine release in mite protease-exposed conjunctival epithelial cells.
Conjunctivitis, Allergic
The effect of topically applied secretory leukocyte protease inhibitor on the eosinophil response in the late phase of allergic conjunctivitis.
Conjunctivitis, Allergic
Urokinase plasminogen activator, uPa receptor, and its inhibitor in vernal keratoconjunctivitis.
Corneal Diseases
Thymic stromal lymphopoietin is expressed in human corneal stromal cells and secreted upon protease-activated receptor 1 activation.
Corneal Dystrophies, Hereditary
The serine protease HtrA1 cleaves misfolded transforming growth factor ?-induced protein (TGFBIp) and induces amyloid formation.
Corneal Edema
A serratial protease causes vascular permeability reaction by activation of the Hageman factor-dependent pathway in guinea pigs.
Corneal Injuries
Characterization of rabbit corneal damage produced by Serratia keratitis and by a serratia protease.
Corneal Injuries
Correlation of Staphylococcus epidermidis Phenotype and its Corneal Virulence.
Corneal Injuries
Immunization against experimental Pseudomonas aeruginosa and Serratia marcescens keratitis. Vaccination with lipopolysaccharide endotoxins and proteases.
Corneal Injuries
Pseudomonas deficient in protease IV has significantly reduced corneal virulence.
Corneal Neovascularization
The inhibition of corneal vascularization with aortic extracts in rabbits.
Corneal Perforation
Desiccating Stress-Induced MMP Production and Activity Worsens Wound Healing in Alkali-Burned Corneas.
Corneal Ulcer
A Pseudomonas aeruginosa strain isolated from a contact lens-induced acute red eye (CLARE) is protease-deficient.
Corneal Ulcer
Effect of phosphoramidon on protection against corneal ulcer caused by elastase and protease from Pseudomonas aeruginosa.
Coronary Artery Disease
An open-label, prospective, observational study of the incidence of coronary artery disease in patients with HIV infection receiving highly active antiretroviral therapy.
Coronary Artery Disease
Anticoagulant versus amidolytic activity of tissue factor pathway inhibitor in coronary artery disease.
Coronary Artery Disease
Association of thrombin generation potential with platelet PAR-1 regulation and P-selectin expression in patients on dual antiplatelet therapy.
Coronary Artery Disease
Coronary artery disease and human immunodeficiency virus infection.
Coronary Artery Disease
Electron beam computed tomography for assessment of coronary artery disease in HIV-infected men receiving antiretroviral therapy.
Coronary Artery Disease
Impact of diabetes on platelet activation in different manifestations of atherosclerosis.
Coronary Artery Disease
Kallikrein-kinin system activation and its interactions with other plasma haemostatic components in the coronary artery disease.
Coronary Artery Disease
Nevirapine-containing antiretroviral therapy in HIV-1 infected patients results in an anti-atherogenic lipid profile.
Coronary Artery Disease
Off-pump coronary artery bypass grafting in a patient with AIDS, acute myocardial infarction, and severe left main coronary artery disease.
Coronary Artery Disease
Prostate-specific antigen, prostate cancer, and disorders of hemostasis.
Coronary Artery Disease
Relation of serum levels of mast cell tryptase of left ventricular systolic function, left ventricular volume or congestive heart failure.
Coronary Artery Disease
Ritonavir-induced lipoatrophy and dyslipidaemia is reversed by the anti-inflammatory drug leflunomide in a PPAR-?-dependent manner.
Coronary Artery Disease
Role of CD40 and ADAMTS13 in von Willebrand factor-mediated endothelial cell-platelet-monocyte interaction.
Coronary Artery Disease
The association of epicardial adipose tissue with coronary artery calcification among HIV-infected men.
Coronary Artery Disease
Viral load of the human immunodeficiency virus could be an independent risk factor for endothelial dysfunction.
Coronary Artery Disease
[Lipodystrophy and lipid metabolism alterations in HIV-infected patients receiving highly active antiretroviral therapy (HAART)]
Coronary Disease
A comparison of different protease inhibitors on coronary heart disease risk.
Coronary Disease
Are increased levels of von Willebrand factor in chronic coronary heart disease caused by decrease in von Willebrand factor cleaving protease activity? A study by an immunoassay with antibody against intact bond 842Tyr-843Met of the von Willebrand factor protein.
Coronary Disease
Cardiovascular risk in patients with HIV Infection: impact of antiretroviral therapy.
Coronary Disease
Clinical aspects of endothelial dysfunction associated with human immunodeficiency virus infection and antiretroviral agents.
Coronary Disease
CONSENSUS STATEMENT BY THE AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS AND AMERICAN COLLEGE OF ENDOCRINOLOGY ON THE COMPREHENSIVE TYPE 2 DIABETES MANAGEMENT ALGORITHM - 2019 EXECUTIVE SUMMARY.
Coronary Disease
CONSENSUS STATEMENT BY THE AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS AND AMERICAN COLLEGE OF ENDOCRINOLOGY ON THE COMPREHENSIVE TYPE 2 DIABETES MANAGEMENT ALGORITHM - 2020 EXECUTIVE SUMMARY.
Coronary Disease
Coronary heart disease associated with the use of human immunodeficiency virus (HIV)-1 protease inhibitors: report of four cases and review.
Coronary Disease
Do protease inhibitors increase the risk for coronary heart disease in patients with HIV-1 infection?
Coronary Disease
Does antiretroviral therapy increase or decrease the risk of cardiovascular disease?
Coronary Disease
Dual-reporter high-throughput screen for small-molecule in vivo inhibitors of plasminogen activator inhibitor type-1 yields a clinical lead candidate.
Coronary Disease
HIV, metabolic syndrome X, inflammation, oxidative stress, and coronary heart disease risk : role of protease inhibitor exposure.
Coronary Disease
Hyperlipidemia associated with HIV protease inhibitor use: pathophysiology, prevalence, risk factors and treatment.
Coronary Disease
Iatrogenic lipodystrophy in HIV patients - the need for very-low-fat diets.
Coronary Disease
Levels and clinical significance of serum homocysteine (Hcy), high-density lipoprotein cholesterol (HDL-C), vaspin, and visfatin in elderly patients with different types of coronary heart disease.
Coronary Disease
Long-term cardiovascular risk with protease inhibitors and management of the dyslipidemia.
Coronary Disease
Potential role of lycopene in targeting proprotein convertase subtilisin/kexin type-9 to combat hypercholesterolemia.
Coronary Disease
Protease inhibitor-based HAART, HDL, and CHD-risk in HIV-infected patients.
Coronary Disease
Thiazolidinediones could improve endothelial dysfunction and risk of premature coronary heart disease in HIV-infected patients.
Coronary Occlusion
Caspase-dependent and serine protease-dependent DNA fragmentation of myocytes in the ischemia-reperfused rabbit heart: these inhibitors do not reduce infarct size.
Coronary Occlusion
Effect of NCO-700, an inhibitor of protease, on myocardial pH decreased by coronary occlusion in dogs.
Coronary Thrombosis
Acute Myocardial Infarction in a 34-Year-Old HIV-Positive Female Patient While Undergoing Active Antiretroviral Therapy Containing a Protease Inhibitor.
Coronavirus Infections
A Review on Expression, Pathological Roles, and Inhibition of TMPRSS2, the Serine Protease Responsible for SARS-CoV-2 Spike Protein Activation.
Coronavirus Infections
Biochemical Characterization of Middle East Respiratory Syndrome Coronavirus Spike Protein Proteolytic Processing.
Coronavirus Infections
Coronaviruses resistant to a 3C-like protease inhibitor are attenuated for replication and pathogenesis, revealing a low genetic barrier but high fitness cost of resistance.
Coronavirus Infections
Correction: Reversal of the Progression of Fatal Coronavirus Infection in Cats by a Broad-Spectrum Coronavirus Protease Inhibitor.
Coronavirus Infections
Feline coronavirus drug inhibits the main protease of SARS-CoV-2 and blocks virus replication.
Coronavirus Infections
In search of drugs to alleviate suppression of the host's innate immune responses against SARS-CoV-2 using a molecular modeling approach.
Coronavirus Infections
L1000 connectivity map interrogation identifies candidate drugs for repurposing as SARS-CoV-2 antiviral therapies.
Coronavirus Infections
Ligand-induced Dimerization of Middle East Respiratory Syndrome (MERS) Coronavirus nsp5 Protease (3CLpro): IMPLICATIONS FOR nsp5 REGULATION AND THE DEVELOPMENT OF ANTIVIRALS.
Coronavirus Infections
Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Infection Mediated by the Transmembrane Serine Protease TMPRSS2.
Coronavirus Infections
Potential inhibitors of coronavirus 3-chymotrypsin-like protease (3CLpro): an in silico screening of alkaloids and terpenoids from African medicinal plants.
Coronavirus Infections
Protease inhibitors broadly effective against feline, ferret and mink coronaviruses.
Coronavirus Infections
Reversal of the Progression of Fatal Coronavirus Infection in Cats by a Broad-Spectrum Coronavirus Protease Inhibitor.
Coronavirus Infections
Targeting the Complement Serine Protease MASP-2 as a Therapeutic Strategy for Coronavirus Infections.
Coronavirus Infections
The TMPRSS2 Inhibitor Nafamostat Reduces SARS-CoV-2 Pulmonary Infection in Mouse Models of COVID-19.
Coronavirus Infections
TMPRSS2 contributes to virus spread and immunopathology in the airways of murine models after coronavirus infection.
Coronavirus Infections
TMPRSS2: A potential target for treatment of influenza virus and coronavirus infections.
Coronavirus Infections
Trypsin Treatment Unlocks Barrier for Zoonotic Bat Coronavirus Infection.
Cough
Protease concentration in amniotic fluid at term and early childhood respiratory symptoms.
Cough
Repurposing the mucolytic cough suppressant and TMPRSS2 protease inhibitor bromhexine for the prevention and management of SARS-CoV-2 infection.
COVID-19
A computational approach for the screening of potential antiviral compounds against SARS-CoV-2 protease: Ionic liquid vs herbal and natural compounds.
COVID-19
A novel class of TMPRSS2 inhibitors potently block SARS-CoV-2 and MERS-CoV viral entry and protect human epithelial lung cells.
COVID-19
A viral infection explanation for Kawasaki disease in general and for COVID-19 virus-related Kawasaki disease symptoms.
COVID-19
ACE inhibition and cardiometabolic risk factors, lung ACE2 and TMPRSS2 gene expression, and plasma ACE2 levels: a Mendelian randomization study.
COVID-19
ACE2 (Angiotensin-Converting Enzyme 2) and TMPRSS2 (Transmembrane Serine Protease 2) Expression and Localization of SARS-CoV-2 Infection in the Human Heart.
COVID-19
ACE2 and TMPRSS2 expression by clinical, HLA, immune, and microbial correlates across 34 human cancers and matched normal tissues: implications for SARS-CoV-2 COVID-19.
COVID-19
Activatable Carbocyanine Dimers for Photoacoustic and Fluorescent Detection of Protease Activity.
COVID-19
Alert to US physicians: DHEA, widely used as an OTC androgen supplement, may exacerbate COVID-19.
COVID-19
Analysis of type I IFN response and T cell activation in severe COVID-19/HIV-1 coinfection: A case report.
COVID-19
Assessment of risk conferred by coding and regulatory variations of TMPRSS2 and CD26 in susceptibility to SARS-CoV-2 infection in human.
COVID-19
Binding and inhibitory effect of ravidasvir on 3CLpro of SARS-CoV-2: a molecular docking, molecular dynamics and MM/PBSA approach.
COVID-19
Binding site analysis of potential protease inhibitors of COVID-19 using AutoDock.
COVID-19
Camostat mesylate inhibits SARS-CoV-2 activation by TMPRSS2-related proteases and its metabolite GBPA exerts antiviral activity.
COVID-19
Can men's increased susceptibility to COVID-19 be attributed to transmembrane protease serine 2?
COVID-19
Cigarette Smoke Stimulates SARS-CoV-2 Internalization by Activating AhR and Increasing ACE2 Expression in Human Gingival Epithelial Cells.
COVID-19
Clinically important drug-drug interactions in patients admitted to hospital with COVID-19: drug pairs, risk factors, and management.
COVID-19
Combination and tricombination therapy to destabilize the structural integrity of COVID-19 by some bioactive compounds with antiviral drugs: insights from molecular docking study.
COVID-19
Computation screening and molecular docking of FDA approved viral protease inhibitors as a potential drug against COVID-19.
COVID-19
Computational Evaluation of the Inhibition Efficacies of HIV Antivirals on SARS-CoV-2 (COVID-19) Protease and Identification of 3D Pharmacophore and Hit Compounds.
COVID-19
Computational studies of drug repurposing and synergism of lopinavir, oseltamivir and ritonavir binding with SARS-CoV-2 protease against COVID-19.
COVID-19
Contributions of human ACE2 and TMPRSS2 in determining host-pathogen interaction of COVID-19.
COVID-19
Crystal Structure of SARS-CoV-2 Main Protease in Complex with the Non-Covalent Inhibitor ML188.
COVID-19
Description of COVID-19 in HIV-infected individuals: a single-centre, prospective cohort.
COVID-19
Direct acting anti-hepatitis C combinations as potential COVID-19 protease inhibitors.
COVID-19
Drug repurposing using computational methods to identify therapeutic options for COVID-19.
COVID-19
Early combination treatment with existing HIV antivirals: an effective treatment for COVID-19?
COVID-19
Effects of Renin-Angiotensin Inhibition on ACE2 (Angiotensin-Converting Enzyme 2) and TMPRSS2 (Transmembrane Protease Serine 2) Expression: Insights Into COVID-19.
COVID-19
Essential oils as an effective alternative for the treatment of COVID-19: Molecular interaction analysis of protease (Mpro) with pharmacokinetics and toxicological properties.
COVID-19
Ethnic differences in alpha-1 antitrypsin deficiency allele frequencies may partially explain national differences in COVID-19 fatality rates.
COVID-19
Evaluation of medicinal herbs as a potential therapeutic option against SARS-CoV-2 targeting its main protease.
COVID-19
Fast Identification of Possible Drug Treatment of Coronavirus Disease -19 (COVID-19) Through Computational Drug Repurposing Study.
COVID-19
Finding potent inhibitors for COVID-19 main protease (Mpro): an in silico approach using SARS-CoV-3CL protease inhibitors for combating CORONA.
COVID-19
First clinical study using HCV protease inhibitor danoprevir to treat COVID-19 patients.
COVID-19
From genomes to molecular dynamics - A bottom up approach in extrication of SARS CoV-2 main protease inhibitors.
COVID-19
Garlic (Allium sativum L.): a potential unique therapeutic food rich in organosulfur and flavonoid compounds to fight with COVID-19.
COVID-19
Hepatitis C Virus Protease Inhibitors Show Differential Efficacy and Interactions with Remdesivir for Treatment of SARS-CoV-2 In Vitro.
COVID-19
Hordatines as a Potential Inhibitor of COVID-19 Main Protease and RNA Polymerase: An In-Silico Approach.
COVID-19
Identification of novel human USP2 inhibitor and its putative role in treatment of COVID-19 by inhibiting SARS-CoV-2 papain-like (PLpro) protease.
COVID-19
Identification of novel transmembrane Protease Serine Type 2 drug candidates for COVID-19 using computational studies.
COVID-19
In silico exploration of novel protease inhibitors against coronavirus 2019 (COVID-19).
COVID-19
In silico inquest reveals the efficacy of Cannabis in the treatment of post-Covid-19 related neurodegeneration.
COVID-19
In silico molecular docking analysis for repurposing approved antiviral drugs against SARS-CoV-2 main protease.
COVID-19
In silico molecular docking of SARS-CoV-2 surface proteins with microbial non-ribosomal peptides: identification of potential drugs.
COVID-19
In silico molecular docking: Evaluation of coumarin based derivatives against SARS-CoV-2.
COVID-19
In silico screening predicts common cold drug Dextromethorphan along with Prednisolone and Dexamethasone can be effective against novel Coronavirus disease (COVID-19).
COVID-19
Influenza virus infection increases ACE2 expression and shedding in human small airway epithelial cells.
COVID-19
Interactions Between Remdesivir, Ribavirin, Favipiravir, Galidesivir, Hydroxychloroquine and Chloroquine with Fragment Molecular of the COVID-19 Main Protease with Inhibitor N3 Complex (PDB ID:6LU7) Using Molecular Docking.
COVID-19
Interrelated Mechanism by Which the Methide Quinone Celastrol, Obtained from the Roots of Tripterygium wilfordii, Inhibits Main Protease 3CLpro of COVID-19 and Acts as Superoxide Radical Scavenger.
COVID-19
Investigating the potential antiviral activity drugs against SARS-CoV-2 by molecular docking simulation.
COVID-19
Lessons Learned to Date on COVID-19 Hyperinflammatory Syndrome: Considerations for Interventions to Mitigate SARS-CoV-2 Viral Infection and Detrimental Hyperinflammation.
COVID-19
Localization of Cell Receptor-Related Genes of SARS-CoV-2 in the Kidney through Single-Cell Transcriptome Analysis.
COVID-19
Lopinavir/Ritonavir and Darunavir/Cobicistat in Hospitalized COVID-19 Patients: Findings From the Multicenter Italian CORIST Study.
COVID-19
Lung and Kidney ACE2 and TMPRSS2 in Renin-Angiotensin System Blocker-Treated Comorbid Diabetic Mice Mimicking Host Factors That Have Been Linked to Severe COVID-19.
COVID-19
MEK inhibitors reduce cellular expression of ACE2, pERK, pRb while stimulating NK-mediated cytotoxicity and attenuating inflammatory cytokines relevant to SARS-CoV-2 infection.
COVID-19
Molecular docking between human TMPRSS2 and SARS-CoV-2 spike protein: conformation and intermolecular interactions.
COVID-19
Molecular docking identification for the efficacy of some zinc complexes with chloroquine and hydroxychloroquine against main protease of COVID-19.
COVID-19
Molecular mechanism of inhibition of COVID-19 main protease by ?-adrenoceptor agonists and adenosine deaminase inhibitors using in silico methods.
COVID-19
Molecular modeling evaluation of the binding effect of five protease inhibitors to COVID-19 main protease.
COVID-19
Molecular modelling of the antiviral action of Resveratrol derivatives against the activity of two novel SARS CoV-2 and 2019-nCoV receptors.
COVID-19
Multicenter interim guidance on use of antivirals for children with COVID-19/SARS-CoV-2.
COVID-19
Multiple relationships between aerosol and COVID-19: A framework for global studies.
COVID-19
Mushroom-derived bioactive compounds potentially serve as the inhibitors of SARS-CoV-2 main protease: An in silico approach.
COVID-19
Mutations and polymorphisms in genes involved in the infections by covid 19: a review.
COVID-19
Naringenin, a flavanone with antiviral and anti-inflammatory effects: A promising treatment strategy against COVID-19.
COVID-19
Natural Killer cell activation, reduced ACE2, TMPRSS2, cytokines G-CSF, M-CSF and SARS-CoV-2-S pseudovirus infectivity by MEK inhibitor treatment of human cells.
COVID-19
Neuroprotective immunity by essential nutrient "Choline" for the prevention of SARS CoV2 infections: An in silico study by molecular dynamics approach.
COVID-19
New Cr(III), Mn(II), Fe(III), Co(II), Ni(II), Zn(II), Cd(II), and Hg(II) Gibberellate Complexes: Synthesis, Structure, and Inhibitory Activity Against COVID-19 Protease.
COVID-19
Pan-Cancer Analysis of Genomic and Prognostic Characteristics Associated With Coronavirus Disease 2019 Regulators.
COVID-19
Pharmacoinformatics and hypothetical studies on allicin, curcumin, and gingerol as potential candidates against COVID-19-associated proteases.
COVID-19
Pharmacotherapeutic considerations in solid organ transplant patients with COVID-19.
COVID-19
Phenolic compounds as promising drug candidates against COVID-19 - An integrated molecular docking and dynamics simulation study.
COVID-19
Postinfection treatment with a protease inhibitor increases survival of mice with a fatal SARS-CoV-2 infection.
COVID-19
Potential of Ficus microcarpa metabolites against SARS-CoV-2 main protease supported by docking studies.
COVID-19
Potential SARS-COV preclinical (in vivo) compounds targeting COVID-19 main protease: a meta-analysis and molecular docking studies.
COVID-19
Protease inhibitor GC376 for COVID-19: Lessons learned from feline infectious peritonitis.
COVID-19
Protease targeted COVID-19 drug discovery and its challenges: Insight into viral main protease (Mpro) and papain-like protease (PLpro) inhibitors.
COVID-19
Protease targeted COVID-19 drug discovery: What we have learned from the past SARS-CoV inhibitors?
COVID-19
QT prolongation associated with hydroxychloroquine and protease inhibitors in COVID-19.
COVID-19
Recombinant ADAMTS13 reduces abnormally up-regulated von Willebrand factor in plasma from patients with severe COVID-19.
COVID-19
Repurposing Antiviral Protease Inhibitors Using Extracellular Vesicles for Potential Therapy of COVID-19.
COVID-19
Repurposing of known anti-virals as potential inhibitors for SARS-CoV-2 main protease using molecular docking analysis.
COVID-19
Repurposing of renin inhibitors as SARS-COV-2 main protease inhibitors: A computational study.
COVID-19
Repurposing the mucolytic cough suppressant and TMPRSS2 protease inhibitor bromhexine for the prevention and management of SARS-CoV-2 infection.
COVID-19
Role of Iron Chelation and Protease Inhibition of Natural Products on COVID-19 Infection.
COVID-19
Safety and efficacy of lopinavir/ritonavir combination in COVID-19: A systematic review, meta-analysis, and meta-regression analysis.
COVID-19
Salvadora persica L.: Toothbrush tree with health benefits and industrial applications - An updated evidence-based review.
COVID-19
SARS-CoV 2; Possible alternative virus receptors and pathophysiological determinants.
COVID-19
SARS-CoV-2 Cysteine-like Protease Antibodies Can Be Detected in Serum and Saliva of COVID-19-Seropositive Individuals.
COVID-19
SARS-CoV-2 proteases PLpro and 3CLpro cleave IRF3 and critical modulators of inflammatory pathways (NLRP12 and TAB1): implications for disease presentation across species.
COVID-19
Scutellaria barbata D. Don Inhibits the Main Proteases (Mpro and TMPRSS2) of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection.
COVID-19
Self-Masked Aldehyde Inhibitors: A Novel Strategy for Inhibiting Cysteine Proteases.
COVID-19
Serine protease inhibitors could be of benefit in the treatment of COVID-19 disease.
COVID-19
Serratiopeptidase, A Serine Protease Anti-Inflammatory, Fibrinolytic, and Mucolytic Drug, Can Be a Useful Adjuvant for Management in COVID-19.
COVID-19
Shape-based Machine Learning Models for the Potential Novel COVID-19 Protease Inhibitors Assisted by Molecular Dynamics Simulation
COVID-19
Simeprevir Potently Suppresses SARS-CoV-2 Replication and Synergizes with Remdesivir.
COVID-19
Simultaneous Treatment of COVID-19 With Serine Protease Inhibitor Camostat and/or Cathepsin L Inhibitor?
COVID-19
Smoking and COVID-19: Similar bronchial ACE2 and TMPRSS2 expression and higher TMPRSS4 expression in current versus never smokers.
COVID-19
Spontaneous binding of potential COVID-19 drugs (Camostat and Nafamostat) to human serine protease TMPRSS2.
COVID-19
Strategies for Targeting SARS CoV-2: Small Molecule Inhibitors-The Current Status.
COVID-19
Structural Basis of Covalent Inhibitory Mechanism of TMPRSS2-Related Serine Proteases by Camostat.
COVID-19
Structural insight to hydroxychloroquine-3C-like proteinase complexation from SARS-CoV-2: inhibitor modelling study through molecular docking and MD-simulation study.
COVID-19
Structural Variability, Expression Profile, and Pharmacogenetic Properties of TMPRSS2 Gene as a Potential Target for COVID-19 Therapy.
COVID-19
Structure-activity relationship (SAR) and molecular dynamics study of withaferin-A fragment derivatives as potential therapeutic lead against main protease (Mpro) of SARS-CoV-2.
COVID-19
Synergistic block of SARS-CoV-2 infection by combined drug inhibition of the host entry factors PIKfyve kinase and TMPRSS2 protease.
COVID-19
Synthesis of novel coumarin analogues: Investigation of molecular docking interaction of SARS-CoV-2 proteins with natural and synthetic coumarin analogues and their pharmacokinetics studies.
COVID-19
Synthesis, molecular docking, and in silico ADMET studies of 4-benzyl-1-(2,4,6-trimethyl-benzyl)-piperidine: Potential Inhibitor of SARS-CoV2.
COVID-19
Target-Centered Drug Repurposing Predictions of Human Angiotensin-Converting Enzyme 2 (ACE2) and Transmembrane Protease Serine Subtype 2 (TMPRSS2) Interacting Approved Drugs for Coronavirus Disease 2019 (COVID-19) Treatment through a Drug-Target Interaction Deep Learning Model.
COVID-19
Targeting novel structural and functional features of coronavirus protease nsp5 (3CLpro, Mpro) in the age of COVID-19.
COVID-19
Targeting SARS-CoV-2 M3CLpro by HCV NS3/4a Inhibitors: In Silico Modeling and In Vitro Screening.
COVID-19
Targeting SARS-CoV-2 RNA-dependent RNA polymerase: An in silico drug repurposing for COVID-19.
COVID-19
Targeting the intestinal TMPRSS2 protease to prevent SARS-CoV-2 entry into enterocytes-prospects and challenges.
COVID-19
Targeting the SARS-CoV-2 main protease using FDA-approved Isavuconazonium, a P2-P3 ?-ketoamide derivative and Pentagastrin: An in-silico drug discovery approach.
COVID-19
The Antiviral and Antimalarial Drug Repurposing in Quest of Chemotherapeutics to Combat COVID-19 Utilizing Structure-Based Molecular Docking.
COVID-19
The contrasting role of nasopharyngeal angiotensin converting enzyme 2 (ACE2) transcription in SARS-CoV-2 infection: A cross-sectional study of people tested for COVID-19 in British Columbia, Canada.
COVID-19
The Current Recommended Drugs and Strategies for the Treatment of Coronavirus Disease (COVID-19).
COVID-19
The impact of curcumin derived polyphenols on the structure and flexibility COVID-19 main protease binding pocket: a molecular dynamics simulation study.
COVID-19
The protease inhibitor lopinavir, boosted with ritonavir, as treatment for COVID-19: a rapid review.
COVID-19
The Resilient Child: Sex-Steroid Hormones and COVID-19 Incidence in Pediatric Patients.
COVID-19
The scRNA-seq Expression Profiling of the Receptor ACE2 and the Cellular Protease TMPRSS2 Reveals Human Organs Susceptible to SARS-CoV-2 Infection.
COVID-19
The TMPRSS2 Inhibitor Nafamostat Reduces SARS-CoV-2 Pulmonary Infection in Mouse Models of COVID-19.
COVID-19
Thromboplasminflammation in COVID-19 Coagulopathy: Three Viewpoints for Diagnostic and Therapeutic Strategies.
COVID-19
TMPRSS2 expression dictates the entry route used by SARS-CoV-2 to infect host cells.
COVID-19
Transcriptional and proteomic insights into the host response in fatal COVID-19 cases.
COVID-19
Ugonin J Acts as a SARS-CoV-2 3C-like Protease Inhibitor and Exhibits Anti-inflammatory Properties.
COVID-19
Uncovering Flexible Active Site Conformations of SARS-CoV-2 3CL Proteases through Protease Pharmacophore Clusters and COVID-19 Drug Repurposing.
COVID-19
Understanding Selenium and Glutathione as Antiviral Factors in COVID-19: Does the Viral Mpro Protease Target Host Selenoproteins and Glutathione Synthesis?
COVID-19
Understanding the binding affinity of noscapines with protease of SARS-CoV-2 for COVID-19 using MD simulations at different temperatures.
COVID-19
Understanding the Role of Corona Virus based on Current Scientific Evidence - a Review with Emerging Important in Pandemic.
COVID-19
Unmasking of crucial structural fragments for coronavirus protease inhibitors and its implications in COVID-19 drug discovery.
COVID-19
Virtual screening, ADME/T, and binding free energy analysis of anti-viral, anti-protease, and anti-infectious compounds against NSP10/NSP16 methyltransferase and main protease of SARS CoV-2.
COVID-19
White Button Mushroom (Agaricus bisporus) Interrupts Tissue AR-TMPRSS2 Expression and Attenuates Pro-inflammatory Cytokines in C57BL/6 Mice: Implication for COVID-19 Dietary Intervention.
COVID-19
[A review on the role of angiotensin-converting enzyme 2 in children with coronavirus disease 2019].
Cowpox
A sequential two-step mechanism for the production of the mature p17:p12 form of caspase-3 in vitro.
Cowpox
Analysis of a large cluster of nonessential genes deleted from a vaccinia virus terminal transposition mutant.
Cowpox
Bcl-2 blocks glucocorticoid- but not Fas- or activation-induced apoptosis in a T cell hybridoma.
Cowpox
CrmA expression in T lymphocytes of transgenic mice inhibits CD95 (Fas/APO-1)-transduced apoptosis, but does not cause lymphadenopathy or autoimmune disease.
Cowpox
Fas- and tumor necrosis factor-induced apoptosis is inhibited by the poxvirus crmA gene product.
Cowpox
Non-essential genes in the vaccinia virus HindIII K fragment: a gene related to serine protease inhibitors and a gene related to the 37K vaccinia virus major envelope antigen.
Cowpox
Plasma membrane localization and fusion inhibitory activity of the cowpox virus serpin SPI-3 require a functional signal sequence and the virus encoded hemagglutinin.
Cowpox
The central executioner of apoptosis: multiple connections between protease activation and mitochondria in Fas/APO-1/CD95- and ceramide-induced apoptosis.
Craniocerebral Trauma
Altered expression of amyloid precursors proteins after traumatic brain injury in rats: in situ hybridization and immunohistochemical study.
Craniocerebral Trauma
Proteolytic enzyme activity in patients with severe head injury and the effect of a proteinase inhibitor.
Craniocerebral Trauma
Thrombin induces long-term potentiation of reactivity to afferent stimulation and facilitates epileptic seizures in rat hippocampal slices: toward understanding the functional consequences of cerebrovascular insults.
Creutzfeldt-Jakob Syndrome
A novel variant of human disease with a protease-sensitive prion protein and heterozygosity methionine/valine at codon 129: Case report.
Creutzfeldt-Jakob Syndrome
Calpain-dependent endoproteolytic cleavage of PrPSc modulates scrapie prion propagation.
Creutzfeldt-Jakob Syndrome
Clinical range and MRI in Creutzfeldt-Jakob disease with heterozygosity at codon 129 and prion protein type 2.
Creutzfeldt-Jakob Syndrome
Co-existence of scrapie prion protein types 1 and 2 in sporadic Creutzfeldt-Jakob disease: its effect on the phenotype and prion-type characteristics.
Creutzfeldt-Jakob Syndrome
Coexistence of protease sensitive and resistant prion protein in 129VV homozygous sporadic Creutzfeldt-Jakob disease: a case report.
Creutzfeldt-Jakob Syndrome
Comparison of the level, distribution and form of disease-associated prion protein in variant and sporadic Creutzfeldt-Jakob diseased brain using conformation-dependent immunoassay and Western blot.
Creutzfeldt-Jakob Syndrome
Diagnosis of prion diseases by RT-QuIC results in improved surveillance.
Creutzfeldt-Jakob Syndrome
Distinct glycoform ratios of protease resistant prion protein associated with PRNP point mutations.
Creutzfeldt-Jakob Syndrome
Effect of protease treatment on plasma infectivity in variant Creutzfeldt-Jakob disease mice.
Creutzfeldt-Jakob Syndrome
Evidence suggesting that PrP is not the infectious agent in Creutzfeldt-Jakob disease.
Creutzfeldt-Jakob Syndrome
Metabotropic glutamate receptor/phospholipase C pathway: a vulnerable target to Creutzfeldt-Jakob disease in the cerebral cortex.
Creutzfeldt-Jakob Syndrome
MM2-Thalamic Creutzfeldt-Jakob Disease: Neuropathological, Biochemical and Transmission Studies Identify a Distinctive Prion Strain.
Creutzfeldt-Jakob Syndrome
Spatial Correlations between the Vacuolation, Prion Protein (PrP(sc)) Deposits and The Cerebral Blood Vessels In Sporadic Creutzfeldt-Jakob Disease.
Creutzfeldt-Jakob Syndrome
Tetracycline affects abnormal properties of synthetic PrP peptides and PrP(Sc) in vitro.
Creutzfeldt-Jakob Syndrome
The efficacy of tetracyclines in peripheral and intracerebral prion infection.
Creutzfeldt-Jakob Syndrome
The prion protein protease sensitivity, stability and seeding activity in variably protease sensitive prionopathy brain tissue suggests molecular overlaps with sporadic Creutzfeldt-Jakob disease.
Creutzfeldt-Jakob Syndrome
Tissue distribution of protease resistant prion protein in variant Creutzfeldt-Jakob disease using a highly sensitive immunoblotting assay.
Creutzfeldt-Jakob Syndrome
Transgenic Overexpression of the Disordered Prion Protein N1 Fragment in Mice Does Not Protect Against Neurodegenerative Diseases Due to Impaired ER Translocation.
Creutzfeldt-Jakob Syndrome
Type 1 protease resistant prion protein and valine homozygosity at codon 129 of PRNP identify a subtype of sporadic Creutzfeldt-Jakob disease.
Crohn Disease
Attenuated induction of epithelial and leukocyte serine antiproteases elafin and secretory leukocyte protease inhibitor in Crohn's disease.
Crohn Disease
Genetic polymorphisms of mannan binding lectin (MBL), serum levels of MBL, the MBL associated serine protease and H-ficolin in patients with Crohn's disease.
Crohn Disease
Growth, phenotype, and function of human intestinal mast cells are tightly regulated by transforming growth factor beta1.
Crohn Disease
Increased proteolysis and leucine aminopeptidase activity in faeces of patients with Crohn's disease.
Crohn Disease
Inflammatory cytokines down-regulate the barrier-protective prostasin-matriptase proteolytic cascade early in experimental colitis.
Crohn Disease
Number, fixation properties, dye-binding and protease expression of duodenal mast cells: comparisons between healthy subjects and patients with gastritis or Crohn's disease.
Crohn Disease
Polymorphisms in the Mannose-Binding Lectin Gene are Associated with Defective Mannose-Binding Lectin Functional Activity in Crohn's Disease Patients.
Crohn Disease
Ramiprilate inhibits functional matrix metalloproteinase activity in Crohn's disease fistulas.
Crush Syndrome
[A case of crush syndrome resulting from continuous compression of the upper arm by automatically cycled blood pressure cuff]
Cryoglobulinemia
Arthralgias and cryoglobulinemia during protease inhibitor therapy in a patient infected with human immunodeficiency virus and hepatitis C virus.
Cryoglobulinemia
Renal involvement in hematological disorders: monoclonal immunoglobulins and nephropathy.
Cryoglobulinemia
Treatment of chronic hepatitis C complicated by mixed cryoglobulinemia with new protease inhibitor, sofosbuvir.
Cryptococcosis
Evidence for interference by immune complexes in the serodiagnosis of cryptococcosis.
Cryptosporidiosis
Decreased prevalence of intestinal cryptosporidiosis in HIV-infected patients concomitant to the widespread use of protease inhibitors.
Cryptosporidiosis
Effect of antiretroviral protease inhibitors alone, and in combination with paromomycin, on the excystation, invasion and in vitro development of Cryptosporidium parvum.
Cryptosporidiosis
The cathepsin-D expression in the cyto-invasive stages of coccidia in intestinal mucosa of chickens, and the relevance of this proteinase for intracellular penetration and spreading of coccidia in host tissues.
Cumulative Trauma Disorders
Supraspinatus tendon overuse results in degenerative changes to tendon insertion region and adjacent humeral cartilage in a rat model.
Cushing Syndrome
Avascular Necrosis of Both Hips From Iatrogenic Cushing 's Syndrome due to Coadministration of Fluticasone and Ritonavir in an HIV-Infected Patient.
Cushing Syndrome
Cushing syndrome and severe adrenal suppression caused by fluticasone and protease inhibitor combination in an HIV-infected adolescent.
Cushing Syndrome
Cushing's syndrome with adrenal suppression induced by inhaled budesonide due to a ritonavir drug interaction in a woman with HIV infection.
Cushing Syndrome
Development of Iatrogenic Cushing Syndrome After Peri-articular Glucocorticoid Injection in an Human Immunodeficiency Virus Patient on Protease Inhibitor Therapy.
Cushing Syndrome
Endocrine and metabolic evaluation of human immunodeficiency virus-infected patients with evidence of protease inhibitor-associated lipodystrophy.
Cushing Syndrome
Exogenous cushing syndrome mimicking human immunodeficiency virus lipodystrophy.
Cushing Syndrome
Iatrogenic Cushing syndrome after a single intramuscular corticosteroid injection and concomitant protease inhibitor therapy.
Cushing Syndrome
Iatrogenic Cushing syndrome and multifocal osteonecrosis caused by the interaction between inhaled fluticasone and ritonavir.
Cushing Syndrome
Iatrogenic Cushing syndrome following lumbar medial branch block in a patient with HIV on ritonavir and darunavir.
Cushing Syndrome
Iatrogenic Cushing's syndrome in HIV-infected patients receiving ritonavir and inhaled fluticasone: description of 4 new cases and review of the literature.
Cushing Syndrome
Iatrogenic Cushing's syndrome with osteoporosis and secondary adrenal failure in human immunodeficiency virus-infected patients receiving inhaled corticosteroids and ritonavir-boosted protease inhibitors: six cases.
Cushing Syndrome
Iatrogenic hypercortisolism complicating triamcinolone acetonide injections in patients with HIV on ritonavir-boosted protease inhibitors.
Cushing Syndrome
Minireview: weapons of lean body mass destruction: the role of ectopic lipids in the metabolic syndrome.
Cushing Syndrome
Raltegravir-induced Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) syndrome - Implications for clinical practice and patient safety.
Cushing Syndrome
Unusual distributions of body fat in AIDS patients: a review of adverse events reported to the Food and Drug Administration.
Cushing Syndrome
Visceral obesity, hypertriglyceridemia and hypercortisolism in a boy with perinatally acquired HIV infection receiving protease inhibitor-containing antiviral treatment.
Cutis Laxa
Elastase-like protease and elastolytic activities expressed in cultured dermal fibroblasts derived from lesional skin of patients with pseudoxanthoma elasticum, actinic elastosis, and cutis laxa.
Cystadenocarcinoma
Thrombomodulin, a receptor for the serine protease thrombin, is decreased in primary tumors and metastases but increased in ascitic fluids of patients with advanced ovarian cancer FIGO IIIc.
Cystadenoma
Secretory leukocyte protease inhibitor in ovarian endometriomas following GnRH agonist therapy.
cystathionine beta-synthase deficiency
X-ray imaging of differential vascular density in MMP-9-/-, PAR-1-/+, hyperhomocysteinemic (CBS-/+) and diabetic (Ins2-/+) mice*
Cystic Fibrosis
A high prevalence of genetic polymorphisms in idiopathic and alcohol-associated chronic pancreatitis patients in Ireland.
Cystic Fibrosis
A monoclonal antibody recognizes structural variation in cystic fibrosis alpha 2-macroglobulin.
Cystic Fibrosis
A Protease Inhibitor Tackles Epithelial Sodium Channels in Cystic Fibrosis.
Cystic Fibrosis
A secretory leukocyte protease inhibitor variant with improved activity against lung infection.
Cystic Fibrosis
A serine protease activity of human serum albumin towards 4-methylumbelliferyl-guanidinobenzoate (MUGB) and diisopropyl fluorophosphate (DEP): implications for the use of MUGB reactivity in amniotic fluid in prenatal diagnosis of cystic fibrosis.
Cystic Fibrosis
A specialized method of sputum collection and processing for therapeutic interventions in cystic fibrosis.
Cystic Fibrosis
Activation of the epithelial sodium channel (ENaC) by the alkaline protease from Pseudomonas aeruginosa.
Cystic Fibrosis
Alginate/Chitosan Particle-Based Drug Delivery Systems for Pulmonary Applications.
Cystic Fibrosis
Amniotic fluid protease activity and the prenatal detection of cystic fibrosis.
Cystic Fibrosis
An Efficient Power Harvesting Mobile Phone-Based Electrochemical Biosensor for Point-of-Care Health Monitoring.
Cystic Fibrosis
Biofilm dispersal cells of a cystic fibrosis Pseudomonas aeruginosa isolate exhibit variability in functional traits likely to contribute to persistent infection.
Cystic Fibrosis
Calprotectin-Mediated Zinc Chelation Inhibits Pseudomonas aeruginosa Protease Activity in Cystic Fibrosis Sputum.
Cystic Fibrosis
CFTR, PRSS1 and SPINK1 mutations in the development of pancreatitis in Brazilian patients.
Cystic Fibrosis
CFTR, SPINK1, PRSS1, and CTRC Mutations Are Not Associated With Pancreatic Cancer in German Patients.
Cystic Fibrosis
Chronic pancreatitis associated with the p.G208A variant of PRSS1 gene in a European patient.
Cystic Fibrosis
Clinical and radiological outcome of patients suffering from chronic pancreatitis associated with gene mutations.
Cystic Fibrosis
Clinical Features and Endoscopic Treatment of Chinese Patients With Hereditary Pancreatitis.
Cystic Fibrosis
Comprehensive screening for PRSS1, SPINK1, CFTR, CTRC and CLDN2 gene mutations in Chinese paediatric patients with idiopathic chronic pancreatitis: a cohort study.
Cystic Fibrosis
Connections Between Genetics and Clinical Data: Role of MCP-1, CFTR, and SPINK-1 in the Setting of Acute, Acute Recurrent, and Chronic Pancreatitis.
Cystic Fibrosis
Cystic fibrosis sputum induces a secretory response from airway gland serous cells that can be prevented by neutrophil protease inhibitors.
Cystic Fibrosis
Cystic fibrosis: protease activity in saliva evaluated with chromogenic substrates.
Cystic Fibrosis
Effect of the addition of protease inhibitors to sputa from cystic fibrosis patients.
Cystic Fibrosis
Elastase Exocytosis by Airway Neutrophils Associates with Early Lung Damage in Cystic Fibrosis Children.
Cystic Fibrosis
Enterohemorrhagic E. coli (EHEC)-Secreted Serine Protease EspP Stimulates Electrogenic Ion Transport in Human Colonoid Monolayers.
Cystic Fibrosis
EPI-hNE4, a proteolysis-resistant inhibitor of human neutrophil elastase and potential anti-inflammatory drug for treating cystic fibrosis.
Cystic Fibrosis
Evidence for alteration of calpain/calpastatin system in PBMC of cystic fibrosis patients.
Cystic Fibrosis
Frequency of CFTR, SPINK1, and Cathepsin B Gene Mutation in North Indian Population: Connections between Genetics and Clinical Data.
Cystic Fibrosis
Genetic counseling for hereditary pancreatitis--the role of molecular genetics testing for the cationic trypsinogen gene, cystic fibrosis and serine protease inhibitor Kazal type 1.
Cystic Fibrosis
Genetic Evaluation of Children with Idiopathic Recurrent Acute Pancreatitis.
Cystic Fibrosis
Genetic, epidemiological, and clinical aspects of hereditary pancreatitis: a population-based cohort study in Denmark.
Cystic Fibrosis
Glycosaminoglycans as Multifunctional Anti-Elastase and Anti-Inflammatory Drugs in Cystic Fibrosis Lung Disease.
Cystic Fibrosis
Granulocyte/macrophage-colony-stimulating factor (GM-CSF) regulates lung innate immunity to lipopolysaccharide through Akt/Erk activation of NFkappa B and AP-1 in vivo.
Cystic Fibrosis
Identification of CFTR, PRSS1, and SPINK1 mutations in 381 patients with pancreatitis.
Cystic Fibrosis
In Vitro Activities against Cystic Fibrosis Pathogens of Synthetic Host Defence Propeptides Processed by Neutrophil Elastase.
Cystic Fibrosis
Incidence, etiology and prognosis of first-time acute pancreatitis in young patients: a population-based cohort study.
Cystic Fibrosis
Incidence, Prevalence, Etiology, and Prognosis of First-Time Chronic Pancreatitis in Young Patients: A Nationwide Cohort Study.
Cystic Fibrosis
Is acute recurrent pancreatitis in children a precursor of chronic pancreatitis? A long-term follow-up study of 93 cases.
Cystic Fibrosis
Methylumbelliferylguanidinobenzoate-reactive proteases in human amniotic fluid: Promising marker for the intrauterine detection of cystic fibrosis.
Cystic Fibrosis
Molecular typing and biological characteristics of Pseudomonas aeruginosa isolated from cystic fibrosis patients in Brazil.
Cystic Fibrosis
Motion--genetic testing is useful in the diagnosis of nonhereditary pancreatic conditions: arguments for the motion.
Cystic Fibrosis
Multifactorial Genesis of Pancreatitis in Primary Hyperparathyroidism: Evidence for "Protective" (PRSS2) and "Destructive" (CTRC) Genetic Factors.
Cystic Fibrosis
Mutation analysis of PRSS1, SPINK1 and CFTR gene in patients with alcoholic and idiopathic chronic pancreatitis: A single center study.
Cystic Fibrosis
Mutation analysis of the cystic fibrosis transmembrane conductance regulator (CFTR) gene, the cationic trypsinogen (PRSS1) gene, and the serine protease inhibitor, Kazal type 1 (SPINK1) gene in patients with alcoholic chronic pancreatitis.
Cystic Fibrosis
N-Arylacyl O-sulfonated aminoglycosides as novel inhibitors of human neutrophil elastase, cathepsin G and proteinase 3.
Cystic Fibrosis
Neutrophil elastase activates near-silent epithelial Na+ channels and increases airway epithelial Na+ transport.
Cystic Fibrosis
Neutrophil elastase inhibition of cell cycle progression in airway epithelial cells in vitro is mediated by p27kip1.
Cystic Fibrosis
Non-peptidic inhibitors of human leukocyte elastase. 1. The design and synthesis of pyridone-containing inhibitors.
Cystic Fibrosis
Pancreatic intraepithelial neoplasia is associated with chronic pancreatitis due to serine protease inhibitor kazal type 1 and cystic fibrosis transmembrane conductance regulator mutations.
Cystic Fibrosis
Phosphonic pseudopeptides as human neutrophil elastase inhibitors--a combinatorial approach.
Cystic Fibrosis
Poly-l-Lysine Compacts DNA, Kills Bacteria, and Improves Protease Inhibition in Cystic Fibrosis Sputum.
Cystic Fibrosis
Prenatal diagnosis of cystic fibrosis by methylumbelliferylguanidinobenzoate protease titration in amniotic fluid.
Cystic Fibrosis
Protease deficiency in plasma of patients with cystic fibrosis. Reduced reaction of 4-methylumbelliferylguanidinobenzoate with plasma of patients with cystic fibrosis.
Cystic Fibrosis
Protease phenotypes of Pseudomonas aeruginosa isolated from patients with cystic fibrosis.
Cystic Fibrosis
Protease production by Pseudomonas aeruginosa isolates from patients with cystic fibrosis.
Cystic Fibrosis
Pulmonary deposition and disappearance of aerosolised secretory leucocyte protease inhibitor.
Cystic Fibrosis
Pulmonary proteases in the cystic fibrosis lung induce interleukin 8 expression from bronchial epithelial cells via a heme/meprin/epidermal growth factor receptor/Toll-like receptor pathway.
Cystic Fibrosis
Quantification and evaluation of the role of antielastin autoantibodies in the emphysematous lung.
Cystic Fibrosis
Reaction of 4-methylumbelliferylguanidinobenzoate with proteases in plasma of patients with cystic fibrosis.
Cystic Fibrosis
Relevance of variants in serum antiproteinases for the course of chronic pancreatitis.
Cystic Fibrosis
Safety and efficacy of recombinant alpha(1)-antitrypsin therapy in cystic fibrosis.
Cystic Fibrosis
Safety and preliminary clinical activity of a novel pancreatic enzyme preparation in pancreatic insufficient cystic fibrosis patients.
Cystic Fibrosis
Screening for cystic fibrosis by analysis of meconium for albumin and protease inhibitors.
Cystic Fibrosis
Study of a novel pancreatic enzyme replacement therapy in pancreatic insufficient subjects with cystic fibrosis.
Cystic Fibrosis
Targeted Gene Next-Generation Sequencing in Chinese Children with Chronic Pancreatitis and Acute Recurrent Pancreatitis.
Cystic Fibrosis
The Etiology and Clinical Course of Chronic Pancreatitis in Children With Early Onset of the Disease.
Cystic Fibrosis
The Prevalence and Characteristics of Genetic Pancreatitis in Children with Chronic and Recurrent Acute Pancreatitis.
Cystic Fibrosis
The Pseudomonas aeruginosa secretory product pyocyanin inactivates alpha1 protease inhibitor: implications for the pathogenesis of cystic fibrosis lung disease.
Cystic Fibrosis
Towards better understanding of the heparin role in NETosis: feasibility of using native mass spectrometry to monitor interactions of neutrophil elastase with heparin oligomers.
Cystic Fibrosis
What are the useful biological and functional markers of early-stage chronic pancreatitis?
Cystitis
Graft pancreatitis and hemorrhagic cystitis. Treatment with bladder irrigation and protease inhibition.
Cystitis
Oral treatment with a vitamin D3 analogue (BXL628) has anti-inflammatory effects in rodent model of interstitial cystitis.
Cystitis
Up-regulation of protease activated receptors in bladder after cyclophosphamide induced cystitis and colocalization with capsaicin receptor (VR1) in bladder nerve fibers.
Cysts
A rhomboid-like protease gene from an interspecies translocation confers resistance to cyst nematodes.
Cysts
Biochemical and enzymatic characterization of decapsulated cysts and nauplii of the brine shrimp Artemia at different developmental stages.
Cysts
Cyst fluid SPINK1 may help to differentiate benign and potentially malignant cystic pancreatic lesions.
Cysts
Differential distribution of soluble and complexed forms of prostate-specific antigen in cyst fluids of women with gross cystic breast disease.
Cysts
Entamoeba invadens: cysteine protease inhibitors block excystation and metacystic development.
Cysts
Global Protease Activity Profiling Provides Differential Diagnosis of Pancreatic Cysts.
Cysts
Heat treatment affects protein quality and protease activity in decapsulated cysts of Artemia when used as starter food for larvae of African catfish Clarias gariepinus (Burchell).
Cysts
Human ovarian tumor-associated trypsin. Its purification and characterization from mucinous cyst fluid and identification as an activator of pro-urokinase.
Cysts
Inhibition of Giardia lamblia excystation by antibodies against cyst walls and by wheat germ agglutinin.
Cysts
Involvement of serine proteases in the excystation and metacystic development of Entamoeba invadens.
Cysts
Prostate-specific antigen found in type I breast cyst fluids is a secretory product of the apocrine cells lining breast gross cysts.
Cysts
Protease activity and phytocystatin expression in Arabidopsis thaliana upon Heterodera schachtii infection.
Cysts
Protease inhibitor expression in soybean roots exhibiting susceptible and resistant interactions with soybean cyst nematode.
Cysts
Purification and characterization of a cytosol protease from dormant cysts of the brine shrimp Artemia.
Cysts
Quantification of prostate-specific antigen immunoreactivity in human breast cyst fluids.
Cysts
Sensitivity of Vermamoeba (Hartmannella) vermiformis cysts to conventional disinfectants and protease.
Cysts
Strategies for the prevention of contact lens-related Acanthamoeba keratitis: a review.
Cysts
Targeted Disruption of Toxoplasma gondii Serine Protease Inhibitor 1 Increases Bradyzoite Cyst Formation In Vitro and Parasite Tissue Burden in Mice.
Cysts
The lysosomal aminopeptidase tripeptidyl peptidase 1 displays increased activity in malignant pancreatic cysts.
Cysts
The Stunning, Glass-Covered Resting Cyst of Maryna umbrellata (Ciliophora, Colpodea).
Cysts
TNF-? blockade suppresses pericystic inflammation following anthelmintic treatment in porcine neurocysticercosis.
Cysts
[Quantitative determination of proteins in the contents of pseudocysts of the maxillary sinus]
Cytomegalovirus Infections
Acute cytomegalovirus infection in AIDS patients with CD4 counts above 100 x 10(6) cells/l following combination antiretroviral therapy including protease inhibitors.
Cytomegalovirus Retinitis
Cystoid macular edema in a patient with acquired immunodeficiency syndrome and past ocular history of cytomegalovirus retinitis after initiation of protease inhibitors.
Cytomegalovirus Retinitis
Cytomegalovirus retinitis in advanced HIV-infected patients treated with protease inhibitors: incidence and outcome over 2 years.
Cytomegalovirus Retinitis
Improved outcome of cytomegalovirus retinitis in AIDS patients after introduction of protease inhibitors.
Cytomegalovirus Retinitis
Incidence and risk factors for developing cytomegalovirus retinitis in HIV-infected patients receiving protease inhibitor therapy. Spanish CMV-AIDS Study Group.
Cytomegalovirus Retinitis
Iritis and hypotony after treatment with intravenous cidofovir for cytomegalovirus retinitis.
Cytomegalovirus Retinitis
Protease inhibitor therapy is associated with markedly prolonged time to relapse and improved survival in AIDS patients with cytomegalovirus retinitis.
Cytomegalovirus Retinitis
Regression of cytomegalovirus retinitis associated with protease-inhibitor treatment in patients with AIDS.
Cytomegalovirus Retinitis
Transient vitreous inflammatory reactions associated with combination antiretroviral therapy in patients with AIDS and cytomegalovirus retinitis.
Cytomegalovirus Retinitis
[Cytomegalovirus retinitis in pediatric patients with AIDS receiving highly active antiretrovirus therapy]
Cytomegalovirus Retinitis
[Impact of anti-retroviral treatment with protease inhibitors on the evolution of cytomegalovirus retinitis in the patient carrying acquired immunodeficiency syndrome]
Dandruff
Retention of corneodesmosomes and increased expression of protease inhibitors in dandruff.
Darier Disease
Genotype-Phenotype Correlations Emerging from the Identification of Missense Mutations in MBTPS2.
Deafness
A novel TMPRSS3 missense mutation in a DFNB8/10 family prevents proteolytic activation of the protein.
Deafness
An integrated genetic and functional analysis of the role of type II transmembrane serine proteases (TMPRSSs) in hearing loss.
Deafness
Autosomal recessive postlingual hearing loss (DFNB8): compound heterozygosity for two novel TMPRSS3 mutations in German siblings.
Deafness
Coexistence of Unverricht-Lundborg disease and congenital deafness: Molecular resolution of a complex comorbidity.
Deafness
Identification of TMPRSS3 as a Significant Contributor to Autosomal Recessive Hearing Loss in the Chinese Population.
Deafness
Insertion of beta-satellite repeats identifies a transmembrane protease causing both congenital and childhood onset autosomal recessive deafness.
Deafness
Novel missense mutations of TMPRSS3 in two consanguineous Tunisian families with non-syndromic autosomal recessive deafness.
Deafness
The transmembrane serine protease (TMPRSS3) mutated in deafness DFNB8/10 activates the epithelial sodium channel (ENaC) in vitro.
Deafness
Tmprss3, a transmembrane serine protease deficient in human DFNB8/10 deafness, is critical for cochlear hair cell survival at the onset of hearing.
Deafness
[The genetics of the protease inhibitor system and osteospongiosis. Statistical study in 199 patients]
Decompression Sickness
The role of L1 loop in the mechanism of rhomboid intramembrane protease GlpG.
Deficiency Diseases
Expanding members and roles of the calpain superfamily and their genetically modified animals.
Dehydration
A Brassica napus transcript encoding a protein related to the Künitz protease inhibitor family accumulates upon water stress in leaves, not in seeds.
Dehydration
Autoprocessing of the protease that degrades small, acid-soluble proteins of spores of Bacillus species is triggered by low pH, dehydration, and dipicolinic acid.
Dehydration
Biochemical Foundations of Health and Energy Conservation in Hibernating Free-Ranging Subadult Brown Bear Ursus arctos.
Dehydration
Combined immunomorphological examination of epon-embedded human kidney biopsies: a comparative study between cryostat, paraffin and consecutive epon-embedded sections for detection and localization of immune deposits.
Dehydration
Effect of cycocel and furfuryl amino purine on protein metabolism of pearl millet (Pennisetum americanum L.) under simulated drought conditions.
Dehydration
Immunohistological staining of antigens on semithin sections of specimens embedded in plastic (GMA-Quetol 523).
Dehydration
Pepper ubiquitin-specific protease, CaUBP12, positively modulates dehydration resistance by enhancing CaSnRK2.6 stability.
Dehydration
Proteomic analyses unraveling water stress response in two Eucalyptus species originating from contrasting environments for aridity.
Dehydration
SPLUNC1 degradation by the cystic fibrosis mucosal environment drives airway surface liquid dehydration.
Dementia
A brain-targeted, modified neurosin (kallikrein-6) reduces ?-synuclein accumulation in a mouse model of multiple system atrophy.
Dementia
A Novel Interaction Between Aging and ER Overload in a Protein Conformational Dementia.
Dementia
Amyloid-beta deposition in the cerebral cortex in Dementia with Lewy bodies is accompanied by a relative increase in AbetaPP mRNA isoforms containing the Kunitz protease inhibitor.
Dementia
Atherosclerosis and central adiposity in a pediatric patient with AIDS treated with HAART: autopsy findings.
Dementia
Clinical course and CSF amyloid beta protein precursor having the site of application of the protease inhibitor (APPI) levels in patients with dementia of the Alzheimer type.
Dementia
Comparison of cathepsin protease activities in brain tissue from normal cases and cases with Alzheimer's disease, Lewy body dementia, Parkinson's disease and Huntington's disease.
Dementia
Curcumin inhibits BACE1 expression through the interaction between ER? and NF?B signaling pathway in SH-SY5Y cells.
Dementia
De novo seven extra repeat expanded mutation in the PRNP gene in an Italian patient with early onset dementia.
Dementia
Development of a selected reaction monitoring mass spectrometry-based assay to detect asparaginyl endopeptidase activity in biological fluids.
Dementia
Differential Alterations in the Attentional Networks of People Living with HIV and Apathy: Preliminary Results and Pharmacoclinical Impact.
Dementia
Human immunodeficiency virus-associated dementia: review of pathogenesis, prophylaxis, and treatment studies of zidovudine therapy.
Dementia
Independent evolution of human immunodeficiency virus (HIV) drug resistance mutations in diverse areas of the brain in HIV-infected patients, with and without dementia, on antiretroviral treatment.
Dementia
Kynostatin and 17beta-estradiol prevent the apoptotic death of human neuroblastoma cells exposed to HIV-1 protease.
Dementia
Lentivirus Mediated Delivery of Neurosin Promotes Clearance of Wild-type ?-Synuclein and Reduces the Pathology in an ?-Synuclein Model of LBD.
Dementia
Low CSF levels of both ?-synuclein and the ?-synuclein cleaving enzyme neurosin in patients with synucleinopathy.
Dementia
Structure-activity relationships in platelet-activating factor (PAF). 10. From PAF antagonism to inhibition of HIV-1 replication.
Dementia
Upregulation of amyloid precursor protein isoforms containing Kunitz protease inhibitor in dementia with Lewy bodies.
Dementia
[A case of HIV encephalopathy with dementia which showed significant improvement after the combination antiretroviral therapy]
Dementia, Multi-Infarct
Quantitative changes in the amyloid beta A4 precursor protein in Alzheimer cerebrospinal fluid.
Dementia, Vascular
Assessment of activation of the plasma kallikrein-kinin system in frontal and temporal cortex in Alzheimer's disease and vascular dementia.
Dementia, Vascular
Excessive urokinase-type plasminogen activator activity in the euglobulin fraction of patients with Alzheimer-type dementia.
Demyelinating Diseases
Activity of a newly identified serine protease in CNS demyelination.
Demyelinating Diseases
Cathepsin C modulates myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis.
Demyelinating Diseases
Critical role for PAR1 in kallikrein 6-mediated oligodendrogliopathy.
Demyelinating Diseases
Crystal structure and biochemical characterization of human kallikrein 6 reveals that a trypsin-like kallikrein is expressed in the central nervous system.
Demyelinating Diseases
Differential expression of protease M/neurosin in oligodendrocytes and their progenitors in an animal model of multiple sclerosis.
Demyelinating Diseases
Effect of cyclosporin A, silica quartz dust, and protease inhibitors on virus-induced demyelination.
Demyelinating Diseases
Evaluation of gelatinases and IL-6 in the cerebrospinal fluid of patients with optic neuritis, multiple sclerosis and other inflammatory neurological diseases.
Demyelinating Diseases
Gelatinase in the cerebrospinal fluid of patients with multiple sclerosis and other inflammatory neurological disorders.
Demyelinating Diseases
Implications of protease M/neurosin in myelination during experimental demyelination and remyelination.
Demyelinating Diseases
Mitosis of Schwann cells and demyelination are induced by the amyloid precursor protein and other protease inhibitors in the rat sciatic nerve.
Demyelinating Diseases
Peripheral neuropathy in the Twitcher mouse involves the activation of axonal caspase 3.
Demyelinating Diseases
Plasminogen activators and matrix metalloproteases, mediators of extracellular proteolysis in inflammatory demyelination of the central nervous system.
Demyelinating Diseases
Sprouting and abnormal contacts of nonmedullated axons, and deposition of extracellular material induced by the amyloid precursor protein (APP) and other protease inhibitors.
Demyelinating Diseases
Suppressive effect of camostat mesilate (FOY 305) on acute experimental allergic encephalomyelitis (EAE).
Demyelinating Diseases
The effect of short-term and chronic immunosuppression on Theiler's virus demyelination.
Dengue
A comparative biochemical analysis of the NS2B(H)-NS3pro protease complex from four dengue virus serotypes.
Dengue
A conformational switch high-throughput screening assay and allosteric inhibition of the flavivirus NS2B-NS3 protease.
Dengue
A dual-purpose synthetic colloidal platform for protease mapping: substrate profiling for Dengue and West Nile virus proteases.
Dengue
A fluorescence quenching assay to discriminate between specific and nonspecific inhibitors of dengue virus protease.
Dengue
A fusogenic peptide expressed on the surface of Salmonella enterica elicits CTL responses to a dengue virus epitope.
Dengue
A model to study the inhibition of nsP2B-nsP3 protease of dengue virus with imidazole, oxazole, triazole thiadiazole, and thiazolidine based scaffolds.
Dengue
A New Class of Dengue and West Nile Virus Protease Inhibitors with Submicromolar Activity in Reporter Gene DENV-2 Protease and Viral Replication Assays.
Dengue
A small molecule inhibitor of dengue virus type 2 protease inhibits the replication of all four dengue virus serotypes in cell culture.
Dengue
A straightforward experimental approach to expression, purification, refolding, and enzymatic analysis of recombinant dengue virus NS2B(H)-NS3pro protease.
Dengue
Activation of dengue protease autocleavage at the NS2B-NS3 junction by recombinant NS3 and GST-NS2B fusion proteins.
Dengue
Amidoxime prodrugs convert to potent cell-active multimodal inhibitors of the dengue virus protease.
Dengue
Analysis of the domain interactions between the protease and helicase of NS3 in dengue and hepatitis C virus.
Dengue
Anti-dengue infectivity evaluation of bioflavonoid from Azadirachta indica by dengue virus serine protease inhibition.
Dengue
Antiviral activities of 15 dengue NS2B-NS3 protease inhibitors using a human cell-based viral quantification assay.
Dengue
Antiviral Cationic Peptides as a Strategy for Innovation in Global Health Therapeutics for Dengue Virus: High Yield Production of the Biologically Active Recombinant Plectasin Peptide.
Dengue
Beyond Basicity: Discovery of Nonbasic DENV-2 Protease Inhibitors with Potent Activity in Cell Culture.
Dengue
Binding of low molecular weight inhibitors promotes large conformational changes in the dengue virus NS2B-NS3 protease: fold analysis by pseudocontact shifts.
Dengue
C-terminal residue optimization and fragment merging: discovery of a potent Peptide-hybrid inhibitor of dengue protease.
Dengue
Characterization of 8-hydroxyquinoline derivatives containing aminobenzothiazole as inhibitors of dengue virus type 2 protease in vitro.
Dengue
Characterization of protease cleavage sites involved in the formation of the envelope glycoprotein and three non-structural proteins of dengue virus type 2, New Guinea C strain.
Dengue
Cleavage of the dengue virus polyprotein at the NS3/NS4A and NS4B/NS5 junctions is mediated by viral protease NS2B-NS3, whereas NS4A/NS4B may be processed by a cellular protease.
Dengue
Computer Aided Screening of Phytochemicals from Garcinia against the Dengue NS2B/NS3 Protease.
Dengue
Construction of a dengue virus type 4 reporter replicon and analysis of temperature-sensitive mutations in non-structural proteins 3 and 5.
Dengue
Construction of dengue virus protease expression plasmid and in vitro protease assay for screening antiviral inhibitors.
Dengue
Correction for Liu et al., "Endoplasmic Reticulum Protein SCAP Inhibits Dengue Virus NS2B3 Protease by Suppressing Its K27-Linked Polyubiquitylation".
Dengue
Crystallization, characterization and measurement of MAD data on crystals of dengue virus NS3 serine protease complexed with mung-bean Bowman-Birk inhibitor.
Dengue
Curcumin Allosterically Inhibits the Dengue NS2B-NS3 Protease by Disrupting Its Active Conformation.
Dengue
Cystargamide B, a cyclic lipodepsipeptide with protease inhibitory activity from Streptomyces sp.
Dengue
Dabrafenib, idelalisib and nintedanib act as significant allosteric modulator for dengue NS3 protease.
Dengue
Dengue protease activity: the structural integrity and interaction of NS2B with NS3 protease and its potential as a drug target.
Dengue
Dengue viral protease interaction with NF-?B inhibitor ?/? results in endothelial cell apoptosis and hemorrhage development.
Dengue
Dengue virus serotype 2 infection alters midgut and carcass gene expression in the Asian tiger mosquito, Aedes albopictus.
Dengue
Dengue viruses cleave STING in humans but not in nonhuman primates, their presumed natural reservoir.
Dengue
Design and Docking Studies of Peptide Inhibitors as Potential Antiviral Drugs for Dengue Virus NS2B/NS3 Protease.
Dengue
Design, structure-based focusing and in silico screening of combinatorial library of peptidomimetic inhibitors of Dengue virus NS2B-NS3 protease.
Dengue
Designing cyclic peptide inhibitor of dengue virus NS3-NS2B protease by using molecular docking approach.
Dengue
Detection and quantification of dengue virus using a novel biosensor system based on dengue NS3 protease activity.
Dengue
Development and utility of an in vitro, fluorescence-based assay for the discovery of novel compounds against dengue 2 viral protease.
Dengue
Development of antiviral inhibitor against dengue 2 targeting Ns3 protein: In vitro and in silico significant studies.
Dengue
Direct evidence of a low barrier hydrogen bond in the catalytic triad of a Serine protease.
Dengue
Discovering key residues of dengue virus NS2b-NS3-protease: New binding sites for antiviral inhibitors design.
Dengue
Discovery of a non-peptidic inhibitor of west nile virus NS3 protease by high-throughput docking.
Dengue
Discovery of Nanomolar Dengue and West Nile Virus Protease Inhibitors Containing a 4-Benzyloxyphenylglycine Residue.
Dengue
Discovery of selective dengue virus inhibitors using combination of molecular fingerprint-based virtual screening protocols, structure-based pharmacophore model development, molecular dynamics simulations and in vitro studies.
Dengue
Discovery, X-ray Crystallography and Antiviral Activity of Allosteric Inhibitors of Flavivirus NS2B-NS3 Protease.
Dengue
DNA-induced 2'3'-cGAMP enhances haplotype-specific human STING cleavage by dengue protease.
Dengue
Docking of noncompetitive inhibitors into dengue virus type 2 protease: understanding the interactions with allosteric binding sites.
Dengue
ER protein SCAP inhibits Dengue virus NS2B3 protease by suppressing its K27-linked polyubiquitylation.
Dengue
Exploration of Carica papaya bioactive compounds as potential inhibitors of dengue NS2B, NS3 and NS5 protease.
Dengue
Facile Synthesis and In Vitro Activity of N-Substituted 1,2-Benzisothiazol-3(2H)-ones against Dengue Virus NS2BNS3 Protease.
Dengue
Flavonoids as noncompetitive inhibitors of Dengue virus NS2B-NS3 protease: inhibition kinetics and docking studies.
Dengue
Flexibility between the protease and helicase domains of the dengue virus NS3 protein conferred by the linker region and its functional implications.
Dengue
Functional characterization of a serine protease inhibitor modulated in the infection of the Aedes aegypti with dengue virus.
Dengue
High-resolution structure of a Kazal-type serine protease inhibitor from the dengue vector Aedes aegypti.
Dengue
High-throughput screening for the identification of small-molecule inhibitors of the flaviviral protease.
Dengue
Homology model of the dengue 2 virus NS3 protease: putative interactions with both substrate and NS2B cofactor.
Dengue
Identification and biochemical characterization of small-molecule inhibitors of west nile virus serine protease by a high-throughput screen.
Dengue
Identification and characterization of nonsubstrate based inhibitors of the essential dengue and West Nile virus proteases.
Dengue
Identification of a novel inhibitor of dengue virus protease through use of a virtual screening drug discovery Web portal.
Dengue
Identification of a putative coreceptor on Vero cells that participates in dengue 4 virus infection.
Dengue
Identification of residues in the dengue virus type 2 NS2B cofactor that are critical for NS3 protease activation.
Dengue
In vitro determination of dengue virus type 2 NS2B-NS3 protease activity with fluorescent peptide substrates.
Dengue
Inhibition of dengue virus replication by novel inhibitors of RNA-dependent RNA polymerase and protease activities.
Dengue
Ligand Accessibility Insights to the Dengue Virus NS3-NS2B Protease Assessed by Long-Timescale Molecular Dynamics Simulations.
Dengue
Ligand-bound structures of the dengue virus protease reveal the active conformation.
Dengue
Lyso-myristoyl phosphatidylcholine micelles sustain the activity of Dengue non-structural (NS) protein 3 protease domain fused with the full-length NS2B.
Dengue
Mitochondrial Import of Dengue Virus NS3 Protease and Cleavage of GrpEL1, a Cochaperone of Mitochondrial Hsp70.
Dengue
Modulation of enzymatic activity of dengue virus nonstructural protein NS3 nucleoside triphosphatase/helicase by poly(U).
Dengue
Monomeric nature of dengue virus NS3 helicase and thermodynamic analysis of the interaction with single-stranded RNA.
Dengue
Mosquito saliva serine protease enhances dissemination of dengue virus into the mammalian host.
Dengue
NMR analysis of the dynamic exchange of the NS2B cofactor between open and closed conformations of the West Nile virus NS2B-NS3 protease.
Dengue
NMR and MD Studies Reveal That the Isolated Dengue NS3 Protease Is an Intrinsically Disordered Chymotrypsin Fold Which Absolutely Requests NS2B for Correct Folding and Functional Dynamics.
Dengue
NS3 protease from flavivirus as a target for designing antiviral inhibitors against dengue virus.
Dengue
Optimization of Assay Conditions for Dengue Virus Protease: Effect of Various Polyols and Nonionic Detergents.
Dengue
Peptide-?-lactam Inhibitors of Dengue and West Nile Virus NS2B-NS3 Protease Display Two Distinct Binding Modes.
Dengue
Phenylalanine and Phenylglycine Analogues as Arginine Mimetics in Dengue Protease Inhibitors.
Dengue
Probing contacts of inhibitor locked in transition states in the catalytic triad of DENV2 type serine protease and its mutants by 1H, 19F and 15?N NMR spectroscopy.
Dengue
Probing the substrate specificity of the dengue virus type 2 NS3 serine protease by using internally quenched fluorescent peptides.
Dengue
Processing of Japanese encephalitis virus non-structural proteins: NS2B-NS3 complex and heterologous proteases.
Dengue
Production and characterization of a monoclonal antibody specific for NS3 protease and the ATPase region of Dengue-2 virus.
Dengue
Productive dengue virus infection of human endothelial cells is directed by heparan sulfate-containing proteoglycan receptors.
Dengue
Prostasin impairs epithelial growth factor receptor activation to suppress dengue virus propagation.
Dengue
Proteochemometrics analysis of substrate interactions with dengue virus NS3 proteases.
Dengue
Pseudo-peptides derived from isomannide as potential inhibitors of serine proteases.
Dengue
Purified NS2B/NS3 serine protease of dengue virus type 2 exhibits cofactor NS2B dependence for cleavage of substrates with dibasic amino acids in vitro.
Dengue
RETREG1 (FAM134B): A new player in human diseases: 15 years after the discovery in cancer.
Dengue
Retro peptide-hybrids as selective inhibitors of the Dengue virus NS2B-NS3 protease.
Dengue
Selection of suitable detergents for obtaining an active dengue protease in its natural form from E. coli.
Dengue
Serine protease inhibitor AEBSF reduces dengue virus infection via decreased cholesterol synthesis.
Dengue
Steady-state cleavage kinetics for dengue virus type 2 ns2b-ns3(pro) serine protease with synthetic peptides.
Dengue
Structural features of NS3 of Dengue virus serotypes 2 and 4 in solution and insight into RNA binding and the inhibitory role of quercetin.
Dengue
Structural insights into a multifunctional inhibitor, 'AMTIN' from tubers of Alocasia macrorrhizos and its possible role in dengue protease (NS2B-NS3) inhibition.
Dengue
Structural Platform for Autolytic Activity of an Intact NS2B-NS3 Protease Complex from Dengue Virus.
Dengue
Structure of the Dengue virus helicase/nucleoside triphosphatase catalytic domain at a resolution of 2.4 A.
Dengue
Structure-guided fragment-based in silico drug design of dengue protease inhibitors.
Dengue
Structure-guided mutagenesis of active site residues in the dengue virus two-component protease NS2B-NS3.
Dengue
Substrate specificity of recombinant dengue 2 virus NS2B-NS3 protease: influence of natural and unnatural basic amino acids on hydrolysis of synthetic fluorescent substrates.
Dengue
Synthesis and biological evaluation of ?-ketoamides as inhibitors of the Dengue virus protease with antiviral activity in cell-culture.
Dengue
Synthesis and evaluation of novel S-benzyl- and S-alkylphthalimide- oxadiazole -benzenesulfonamide hybrids as inhibitors of dengue virus protease.
Dengue
Synthesis and molecular modelling studies of novel sulphonamide derivatives as dengue virus 2 protease inhibitors.
Dengue
Synthesis and structure-activity relationships of small-molecular di-basic esters, amides and carbamates as flaviviral protease inhibitors.
Dengue
Targeting the NS2B-NS3 protease of tick-borne encephalitis virus with pan-flaviviral protease inhibitors.
Dengue
The identification of active compounds in Ganoderma lucidum var. antler extract inhibiting dengue virus serine protease and its computational studies.
Dengue
The serine protease and RNA-stimulated nucleoside triphosphatase and RNA helicase functional domains of dengue virus type 2 NS3 converge within a region of 20 amino acids.
Dengue
Thiazolidinone-Peptide Hybrids as Dengue Virus Protease Inhibitors with Antiviral Activity in Cell Culture.
Dengue
Transplantation of a hydrogen bonding network from West Nile virus protease onto Dengue-2 protease improves catalytic efficiency and sheds light on substrate specificity.
Dengue
Two-stage ML Classifier for Identifying Host Protein Targets of the Dengue Protease.
Dengue
Use of NS3 consensus primers for the polymerase chain reaction amplification and sequencing of dengue viruses and other flaviviruses.
Dengue
Virtual screening of eighteen million compounds against dengue virus: Combined molecular docking and molecular dynamics simulations study.
Dengue
West Nile Virus (WNV) protease and membrane interactions revealed by NMR spectroscopy.
Dengue
Yellow fever virus NS2B/NS3 protease: Hydrolytic Properties and Substrate Specificity.
Dental Caries
Transcription of clpP is enhanced by a unique tandem repeat sequence in Streptococcus mutans.
Dental Plaque
Identification of proteases from periodontopathogenic bacteria as activators of latent human neutrophil and fibroblast-type interstitial collagenases.
Dental Plaque
Relation between the presence of supragingival calculus and protease activity in dental plaque.
Dermatitis
Effects of potato-derived protease inhibitors on perianal dermatitis after colon resection for long-segment Hirschsprung's disease.
Dermatitis
IGFBP-1 protease activity and IGFBP-1 fragments in a patient with multiple myeloma.
Dermatitis
PAR-1 signaling on macrophages is required for effective in vivo delayed-type hypersensitivity responses.
Dermatitis
Physiological and health-related response of broiler chickens fed diets containing raw, full-fat soya bean meal supplemented with microbial protease.
Dermatitis
Potato tuber proteins efficiently inhibit human faecal proteolytic activity: implications for treatment of peri-anal dermatitis.
Dermatitis
Purification and characterization of protease produced by Staphylococcus aureus isolated from a diseased chicken.
Dermatitis
Structural gene and strain specificity of a novel cysteine protease produced by Staphylococcus aureus isolated from a diseased chicken.
Dermatitis
Use of an emollient-containing diaper and pH-buffered wipe regimen restores skin pH and reduces residual enzymatic activity.
Dermatitis, Atopic
A nonsynonymous substitution of cystatin A, a cysteine protease inhibitor of house dust mite protease, leads to decreased mRNA stability and shows a significant association with atopic dermatitis.
Dermatitis, Atopic
Development of stratum corneum chymotrypsin-like protease activity and natural moisturising factors from birth to 4 weeks of age compared to adults.
Dermatitis, Atopic
Evidence for degradation of cytokines in the serum of patients with atopic dermatitis by calcium-dependent protease.
Dermatitis, Atopic
Exonic mutations associated with atopic dermatitis disrupt lympho-epithelial Kazal-type related inhibitor action and enhance its degradation.
Dermatitis, Atopic
Filaggrin loss-of-function mutations are associated with enhanced expression of IL-1 cytokines in the stratum corneum of patients with atopic dermatitis and in a murine model of filaggrin deficiency.
Dermatitis, Atopic
Generation of a quenched phosphonate activity-based probe for labelling the active KLK7 protease.
Dermatitis, Atopic
Generation of recombinant antibodies against human tissue kallikrein 7 to treat skin diseases.
Dermatitis, Atopic
Genetic polymorphisms in serine protease inhibitor Kazal-type 5 and risk of atopic dermatitis: A meta-analysis.
Dermatitis, Atopic
Gingival Crevicular Fluid Zinc- and Aspartyl-Binding Protease Profile of Individuals with Moderate/Severe Atopic Dermatitis.
Dermatitis, Atopic
Identification of bacterial biofilm and the Staphylococcus aureus derived protease, staphopain, on the skin surface of patients with atopic dermatitis.
Dermatitis, Atopic
Identification of lympho-epithelial Kazal-type inhibitor 2 in human skin as a kallikrein-related peptidase 5-specific protease inhibitor.
Dermatitis, Atopic
Imre schneider, ferenc harangi, béla seb?k: clinical and pathological aspects of atopic dermatitis.
Dermatitis, Atopic
Increased mass levels of certain serine proteases in the stratum corneum in acute eczematous atopic skin.
Dermatitis, Atopic
Influence of skin penetration enhancers on skin barrier function and skin protease activity.
Dermatitis, Atopic
Keynote from Japan 5th georg rajka international symposium on atopic dermatitis, kyoto, may 11-13, 2008.
Dermatitis, Atopic
Mite and cockroach allergens activate protease-activated receptor 2 and delay epidermal permeability barrier recovery.
Dermatitis, Atopic
Mite serine protease activates protease-activated receptor-2 and induces cytokine release in human keratinocytes.
Dermatitis, Atopic
Multifaceted Analyses of Epidermal Serine Protease Activity in Patients with Atopic Dermatitis.
Dermatitis, Atopic
Netherton syndrome: skin inflammation and allergy by loss of protease inhibition.
Dermatitis, Atopic
Polymorphisms in SPINK5 are not associated with asthma in a Dutch population.
Dermatitis, Atopic
Protease and protease-activated receptor-2 signaling in the pathogenesis of atopic dermatitis.
Dermatitis, Atopic
Protease-resistant fraction of smoked, dried bonito alleviates atopic dermatitis-like skin lesions in NC/Nga mice.
Dermatitis, Atopic
Serine protease inhibitor lymphoepithelial Kazal type-related inhibitor tends to be decreased in atopic dermatitis.
Dermatitis, Atopic
SERPINB3/B4 contributes to early inflammation and barrier dysfunction in an experimental murine model of atopic dermatitis.
Dermatitis, Atopic
Staphylococcus epidermidis protease EcpA can be a deleterious component of the skin microbiome in atopic dermatitis.
Dermatitis, Atopic
The 420K LEKTI variant alters LEKTI proteolytic activation and results in protease deregulation: implications for atopic dermatitis.
Dermatitis, Atopic
The novel protease inhibitor SRD441 ointment is not effective in the treatment of adult subjects with atopic dermatitis: results of a randomized, vehicle-controlled study.
Dermatitis, Atopic
Therapeutic Implications of a Barrier-based Pathogenesis of Atopic Dermatitis.
Dermatitis, Exfoliative
Transgenic kallikrein 5 mice reproduce major cutaneous and systemic hallmarks of Netherton syndrome.
Dermatitis, Phototoxic
Photosensitizer-conjugated gold nanorods for enzyme-activatable fluorescence imaging and photodynamic therapy.
Dermatitis, Phototoxic
Using the singlet oxygen scavenging property of carotenoid in photodynamic molecular beacons to minimize photodamage to non-targeted cells.
Diabetes Complications
In vitro and in vivo prevention of HIV protease inhibitor-induced insulin resistance by a novel small molecule insulin receptor activator.
Diabetes Complications
Modern diets and diseases: NO-zinc balance. Under Th1, zinc and nitrogen monoxide (NO) collectively protect against viruses, AIDS, autoimmunity, diabetes, allergies, asthma, infectious diseases, atherosclerosis and cancer.
Diabetes Complications
Network pharmacology analysis of Chaihu Lizhong Tang treating non-alcoholic fatty liver disease.
Diabetes Complications
Protease inhibitor-induced diabetic complications : incidence, management and prevention.
Diabetes Mellitus
A case-control study on the association of common variants of CAPN10 gene and the risk of type 2 diabetes in an Iranian population.
Diabetes Mellitus
A Novel SERPINB1 Single-Nucleotide Polymorphism Associated With Glycemic Control and ?-Cell Function in Egyptian Type 2 Diabetic Patients.
Diabetes Mellitus
Abnormal lipids and the acquired immunodeficiency syndrome: is there a problem and what should we do about it?
Diabetes Mellitus
Apparent Resolution of Type 2 Diabetes Mellitus after Initiation of Potent Antiretroviral Therapy in a Man from Africa with HIV Infection.
Diabetes Mellitus
Association between the use of protease inhibitors in highly active antiretroviral therapy and incidence of diabetes mellitus and/or metabolic syndrome in HIV-infected patients: A systematic review and meta-analysis.
Diabetes Mellitus
Calpain-10 regulates actin dynamics by proteolysis of microtubule-associated protein 1B.
Diabetes Mellitus
Cardiovascular disease in patients infected with the human immunodeficiency virus.
Diabetes Mellitus
Decreased ternary complex formation and predominance of a 29 kDa IGFBP-3 fragment in human fetal serum.
Diabetes Mellitus
Dyslipidaemia associated with antiretroviral therapy in HIV-infected patients.
Diabetes Mellitus
Effects of the GLP-1 receptor agonist lixisenatide on postprandial glucose and gastric emptying - preclinical evidence.
Diabetes Mellitus
Effects of troglitazone on insulin sensitivity in HIV-infected patients with protease inhibitor-associated diabetes mellitus.
Diabetes Mellitus
Effects of vaspin on pancreatic ? cell secretion via PI3K/Akt and NF-?B signaling pathways.
Diabetes Mellitus
Elevated Resting and Postprandial Digestive Proteolytic Activity in Peripheral Blood of Individuals With Type-2 Diabetes Mellitus, With Uncontrolled Cleavage of Insulin Receptors.
Diabetes Mellitus
Evaluation of aging, diabetes mellitus, and skin wounds by scanning acoustic microscopy with protease digestion.
Diabetes Mellitus
Expression, genomic structure and mapping of the thymus specific protease prss16: a candidate gene for insulin dependent diabetes mellitus susceptibility.
Diabetes Mellitus
Factors associated with statin selection among privately insured commercial and Medicare patients.
Diabetes Mellitus
Factors associated with the incidence of type 2 diabetes mellitus in HIV-infected participants in the Swiss HIV Cohort Study.
Diabetes Mellitus
Functional activities and nonenzymatic glycosylation of plasma proteinase inhibitors in diabetes.
Diabetes Mellitus
Genes encoding tumor necrosis factor alpha and granzyme A are expressed during development of autoimmune diabetes.
Diabetes Mellitus
Glycaemic consequences of HIV and highly active antiretroviral therapy: a pilot study and review of literature.
Diabetes Mellitus
Highly active antiretroviral therapy-associated metabolic syndrome and cardiovascular risk.
Diabetes Mellitus
HIV-associated lipodystrophy: pathogenesis, prognosis, treatment, and controversies.
Diabetes Mellitus
Hyperglycemia associated with protease inhibitors in an urban HIV-infected minority patient population.
Diabetes Mellitus
Impaired glucose metabolism in HIV-infected pregnant women: a retrospective analysis.
Diabetes Mellitus
Longer-term immunologic effects and side effects of successful antiretroviral therapy.
Diabetes Mellitus
Management of infection among Medicare beneficiaries with HIV/AIDS: risk of diabetes with protease inhibitors and associated racial disparities using big data approach.
Diabetes Mellitus
Metabolic and cardiovascular complications of highly active antiretroviral therapy for HIV infection.
Diabetes Mellitus
Metformin in an HIV-infected patient with protease inhibitor-induced diabetic ketoacidosis.
Diabetes Mellitus
New Molecular Insights into the Inhibition of Dipeptidyl Peptidase-4 by Natural Cyclic Peptide Oxytocin.
Diabetes Mellitus
New-onset diabetes mellitus associated with protease inhibitor therapy in an HIV-positive patient: case report and review.
Diabetes Mellitus
Plasma inactive renin in patients with diabetes mellitus: effects of standing and the relation to serum protease inhibitor.
Diabetes Mellitus
Plasma levels of the von Willebrand factor-cleaving protease in physiological and pathological conditions in children.
Diabetes Mellitus
PPARgamma transcriptionally regulates the expression of insulin-degrading enzyme in primary neurons.
Diabetes Mellitus
Prevalence and incidence of diabetes in HIV-infected minority patients on protease inhibitors.
Diabetes Mellitus
Prevalence of chronic kidney disease among HIV-1-infected patients receiving a combination antiretroviral therapy.
Diabetes Mellitus
Prevalence of Nephrotoxicity in HIV Patients Treated with Tenofovir Disoproxil Fumarate: A Single-center Observational Study.
Diabetes Mellitus
Protease inhibitor therapy-associated lipodystrophy, hypertriglyceridaemia and diabetes mellitus.
Diabetes Mellitus
Protease inhibitor use and the incidence of diabetes mellitus in a large cohort of HIV-infected women.
Diabetes Mellitus
Protease inhibitor-associated diabetes mellitus: a potential cause of morbidity and mortality.
Diabetes Mellitus
Proteomic analysis of serum biomarkers for prediabetes using the Long-Evans Agouti rat, a spontaneous animal model of type 2 diabetes mellitus.
Diabetes Mellitus
Resolution of diabetes after initiation of antiretroviral therapy in two human immunodeficiency virus-infected patients.
Diabetes Mellitus
Reviewing the cardiovascular complications of HIV infection after the introduction of highly active antiretroviral therapy.
Diabetes Mellitus
Risk factors for new-onset diabetes mellitus in patients receiving protease inhibitor therapy.
Diabetes Mellitus
Risk of premature atherosclerosis and ischemic heart disease associated with HIV infection and antiretroviral therapy.
Diabetes Mellitus
Tenofovir Disoproxil Fumarate-Associated Renal Dysfunction Among Adult People Living with HIV at the University of Gondar Comprehensive Specialized Hospital, Northwest Ethiopia, 2019: A Comparative Retrospective Cohort Study.
Diabetes Mellitus
Tenofovir Effect on the Kidneys of HIV-Infected Patients: A Double-Edged Sword?
Diabetes Mellitus
Tenofovir use and urinary biomarkers among HIV-infected women in the Women's Interagency HIV Study (WIHS).
Diabetes Mellitus
Tenofovir use is associated with a reduction in calculated glomerular filtration rates in the Swiss HIV Cohort Study.
Diabetes Mellitus
The serine protease granzyme B as an inflammatory marker, in relation to the insulin receptor cleavage in human obesity and type 2 diabetes mellitus.
Diabetes Mellitus
Treatment with protease inhibitors associated with peripheral insulin resistance and impaired oral glucose tolerance in HIV-1-infected patients.
Diabetes Mellitus
Vaspin regulates the osteogenic differentiation of MC3T3-E1 through the PI3K-Akt/miR-34c loop.
Diabetes Mellitus
[Activity of serum and lymphocyte serine proteases of patients with diabetes mellitus and the possibility of using protease blockers in combined therapy]
Diabetes Mellitus
[Diabetes mellitus and protease inhibitors. A complication to take into account]
Diabetes Mellitus
[Diabetes mellitus associated with protease inhibitors in HIV infected patients]
Diabetes Mellitus
[Protease inhibitor-associated hypertriglyceridemia and diabetes mellitus in HIV-infected patients]
Diabetes Mellitus, Experimental
[Effect of bacterial protease and alloxan diabetes on wound healing in the gingiva of rats]
Diabetes Mellitus, Type 1
? 1-antitrypsin enhances insulin secretion and prevents cytokine-mediated apoptosis in pancreatic ?-cells.
Diabetes Mellitus, Type 1
An association between Type 2 diabetes and alpha-antitrypsin deficiency.
Diabetes Mellitus, Type 1
Association analysis in type 1 diabetes of the PRSS16 gene encoding a thymus-specific serine protease.
Diabetes Mellitus, Type 1
Increased 24 h mean insulin-like growth factor binding protein-3 proteolytic activity in pubertal type 1 diabetic boys.
Diabetes Mellitus, Type 1
Insulin treatment normalizes reduced free insulin-like growth factor-I concentrations in diabetic children.
Diabetes Mellitus, Type 1
Insulin-like growth factor binding protein-3 proteolysis in children with insulin-dependent diabetes mellitus: a possible role for insulin in the regulation of IGFBP-3 protease activity.
Diabetes Mellitus, Type 1
Insulin-like growth factor binding proteins (IGFBPs) in serum and urine and IGFBP-2 protease activity in patients with insulin-dependent diabetes mellitus.
Diabetes Mellitus, Type 1
Major histocompatibility complex-encoded antigen processing gene polymorphism in IDDM.
Diabetes Mellitus, Type 1
Protease profiling of different biofluids in type 1 diabetes mellitus.
Diabetes Mellitus, Type 1
Proteases and protease inhibitors of urinary extracellular vesicles in diabetic nephropathy.
Diabetes Mellitus, Type 1
Roles for cathepsins S, L, and B in insulitis and diabetes in the NOD mouse.
Diabetes Mellitus, Type 1
Serum levels of insulin-like growth factor-I and insulin-like growth factor binding protein-3 in children with insulin-dependent diabetes mellitus.
Diabetes Mellitus, Type 1
Susceptibility to type 1 diabetes in the Senegalese population is linked to HLA-DQ and not TAP and LMP genes.
Diabetes Mellitus, Type 1
Target antigen of islet cell antibody in Japanese insulin-dependent diabetes mellitus.
Diabetes Mellitus, Type 1
The use of granzyme A as a marker of heart transplant rejection in cyclosporine or anti-CD4 monoclonal antibody-treated rats.
Diabetes Mellitus, Type 1
Thymus-specific serine protease controls autoreactive CD4 T cell development and autoimmune diabetes in mice.
Diabetes Mellitus, Type 1
[Relationship of polymorphism of LMP2 gene to insulin-dependent diabetes mellitus and DR3 gene]
Diabetes Mellitus, Type 2
A case-control study on the association of common variants of CAPN10 gene and the risk of type 2 diabetes in an Iranian population.
Diabetes Mellitus, Type 2
A Non-Perturbative Molecular Grafting Strategy for Stable and Potent Therapeutic Peptide Ligands.
Diabetes Mellitus, Type 2
A Novel Purification Procedure for Active Recombinant Human DPP4 and the Inability of DPP4 to Bind SARS-CoV-2.
Diabetes Mellitus, Type 2
A Novel SERPINB1 Single-Nucleotide Polymorphism Associated With Glycemic Control and ?-Cell Function in Egyptian Type 2 Diabetic Patients.
Diabetes Mellitus, Type 2
Apparent Resolution of Type 2 Diabetes Mellitus after Initiation of Potent Antiretroviral Therapy in a Man from Africa with HIV Infection.
Diabetes Mellitus, Type 2
Association of SERPINE1 rs6092 with type 2 diabetes and related metabolic traits in a Chinese population.
Diabetes Mellitus, Type 2
Associations of TMPRSS6 Polymorphisms with Gestational Diabetes Mellitus in Chinese Han Pregnant Women: a Preliminary Cohort Study.
Diabetes Mellitus, Type 2
Calpain-10 regulates actin dynamics by proteolysis of microtubule-associated protein 1B.
Diabetes Mellitus, Type 2
CONSENSUS STATEMENT BY THE AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS AND AMERICAN COLLEGE OF ENDOCRINOLOGY ON THE COMPREHENSIVE TYPE 2 DIABETES MANAGEMENT ALGORITHM - 2019 EXECUTIVE SUMMARY.
Diabetes Mellitus, Type 2
CONSENSUS STATEMENT BY THE AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS AND AMERICAN COLLEGE OF ENDOCRINOLOGY ON THE COMPREHENSIVE TYPE 2 DIABETES MANAGEMENT ALGORITHM - 2020 EXECUTIVE SUMMARY.
Diabetes Mellitus, Type 2
Covalent binding of glutathione on magnetic nanoparticles: Application for immobilizing small fragment ubiquitin-like-specific protease 1.
Diabetes Mellitus, Type 2
Dipeptide boronic acid inhibitors of dipeptidyl peptidase IV: determinants of potency and in vivo efficacy and safety.
Diabetes Mellitus, Type 2
Dipeptidyl peptidase inhibitors as new drugs for the treatment of type 2 diabetes.
Diabetes Mellitus, Type 2
Dipeptidyl peptidase IV inhibitors in diabetes: more than inhibition of glucagon-like peptide-1 metabolism?
Diabetes Mellitus, Type 2
Dissecting the Physiology and Pathophysiology of Glucagon-Like Peptide-1.
Diabetes Mellitus, Type 2
Effects of the GLP-1 receptor agonist lixisenatide on postprandial glucose and gastric emptying - preclinical evidence.
Diabetes Mellitus, Type 2
Elevated Resting and Postprandial Digestive Proteolytic Activity in Peripheral Blood of Individuals With Type-2 Diabetes Mellitus, With Uncontrolled Cleavage of Insulin Receptors.
Diabetes Mellitus, Type 2
Factors associated with the incidence of type 2 diabetes mellitus in HIV-infected participants in the Swiss HIV Cohort Study.
Diabetes Mellitus, Type 2
Genetic variation in the vaspin gene affects circulating serum vaspin concentrations.
Diabetes Mellitus, Type 2
Highly active antiretroviral therapy-associated metabolic syndrome and cardiovascular risk.
Diabetes Mellitus, Type 2
Increased proteolysis of insulin-like growth factor-binding protein-3 (IGFBP-3) in noninsulin-dependent diabetes mellitus serum, with elevation of a 29-kilodalton (kDa) glycosylated IGFBP-3 fragment contained in the approximately 130- to 150-kDa ternary complex.
Diabetes Mellitus, Type 2
Inhibition of Serine Protease Activity Protects Against High Fat Diet-Induced Inflammation and Insulin Resistance.
Diabetes Mellitus, Type 2
Loss of DPP4 activity is related to a prothrombogenic status of endothelial cells: implications for the coronary microvasculature of myocardial infarction patients.
Diabetes Mellitus, Type 2
Matrix metalloproteinases contribute to insulin insufficiency in Zucker diabetic fatty rats.
Diabetes Mellitus, Type 2
Metabolic and cardiovascular complications of highly active antiretroviral therapy for HIV infection.
Diabetes Mellitus, Type 2
Neuroprotective effects of glucose-dependent insulinotropic polypeptide in Alzheimer's disease.
Diabetes Mellitus, Type 2
Neutrophil proteinase 3 induces diabetes in a mouse model of glucose tolerance.
Diabetes Mellitus, Type 2
PPARgamma transcriptionally regulates the expression of insulin-degrading enzyme in primary neurons.
Diabetes Mellitus, Type 2
Proteolysis of insulin-like growth factor-binding protein-3 is increased in urine from patients with diabetic nephropathy.
Diabetes Mellitus, Type 2
Proteomic analysis of serum biomarkers for prediabetes using the Long-Evans Agouti rat, a spontaneous animal model of type 2 diabetes mellitus.
Diabetes Mellitus, Type 2
Recent advances in non-peptidomimetic dipeptidyl peptidase 4 inhibitors: medicinal chemistry and preclinical aspects.
Diabetes Mellitus, Type 2
Regulation of muscle cathepsin B proteolytic activity in protein-depleted patients with chronic diseases.
Diabetes Mellitus, Type 2
Reviewing the cardiovascular complications of HIV infection after the introduction of highly active antiretroviral therapy.
Diabetes Mellitus, Type 2
Seco-prolinenitrile inhibitors of dipeptidyl peptidase IV define minimal pharmacophore requirements at P1.
Diabetes Mellitus, Type 2
The calcium-dependent protease calpain causes endothelial dysfunction in type 2 diabetes.
Diabetes Mellitus, Type 2
The incretin hormones: from scientific discovery to practical therapeutics.
Diabetes Mellitus, Type 2
The mechanism of insulin resistance caused by HIV protease inhibitor therapy.
Diabetes Mellitus, Type 2
The serine protease granzyme B as an inflammatory marker, in relation to the insulin receptor cleavage in human obesity and type 2 diabetes mellitus.
Diabetes Mellitus, Type 2
Therapeutic dose of HIV-1 protease inhibitor saquinavir does not permanently influence early insulin signaling.
Diabetes Mellitus, Type 2
Vaspin Attenuates RANKL-Induced Osteoclast Formation in RAW264.7 Cells.
Diabetes Mellitus, Type 2
Vaspin can not inhibit TNF-alpha-induced inflammation of human umbilical vein endothelial cells.
Diabetes, Gestational
Associations of TMPRSS6 Polymorphisms with Gestational Diabetes Mellitus in Chinese Han Pregnant Women: a Preliminary Cohort Study.
Diabetes, Gestational
Could abnormalities in insulin-like growth factors and their binding proteins during pregnancy result in gestational diabetes?
Diabetes, Gestational
Obstetric and perinatal complications in HIV-infected women. Analysis of a cohort of 167 pregnancies between 1997 and 2003.
Diabetic Foot
Expression of matrix metalloproteinases and growth factors in diabetic foot wounds treated with a protease absorbent dressing.
Diabetic Foot
Expression of Matrix-Metalloproteases in the Fluid of Chronic Diabetic Foot Wounds Treated with a Protease Absorbent Dressing.
Diabetic Foot
Mechanism of action of PROMOGRAN, a protease modulating matrix, for the treatment of diabetic foot ulcers.
Diabetic Foot
The Effectiveness of Negative Pressure Therapy in Diabetic Foot Ulcers with Elevated Protease Activity: A Case Series.
Diabetic Ketoacidosis
CONSENSUS STATEMENT BY THE AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS AND AMERICAN COLLEGE OF ENDOCRINOLOGY ON THE COMPREHENSIVE TYPE 2 DIABETES MANAGEMENT ALGORITHM - 2019 EXECUTIVE SUMMARY.
Diabetic Ketoacidosis
CONSENSUS STATEMENT BY THE AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS AND AMERICAN COLLEGE OF ENDOCRINOLOGY ON THE COMPREHENSIVE TYPE 2 DIABETES MANAGEMENT ALGORITHM - 2020 EXECUTIVE SUMMARY.
Diabetic Ketoacidosis
Metformin in an HIV-infected patient with protease inhibitor-induced diabetic ketoacidosis.
Diabetic Ketoacidosis
[Diabetic ketoacidosis in an HIV-infected patient undergoing antiretroviral therapy]
Diabetic Nephropathies
Activated protein C ameliorates diabetic nephropathy by epigenetically inhibiting the redox enzyme p66Shc.
Diabetic Nephropathies
Advanced glycation end products regulate extracellular matrix protein and protease expression by human glomerular mesangial cells.
Diabetic Nephropathies
Effect of camostat mesilate on urinary protein excretion in three patients with advanced diabetic nephropathy.
Diabetic Nephropathies
Effect of proteinase inhibitor camostat mesilate on nephrotic syndrome with diabetic nephropathy.
Diabetic Nephropathies
Effects of the chymase inhibitor fulacimstat in diabetic kidney disease-results from the CADA DIA trial.
Diabetic Nephropathies
Erratum: Protease activated receptor 2 in diabetic nephropathy: a double edged sword.
Diabetic Nephropathies
Immunofluorescence staining in unfixed or fixed renal biopsy specimens from patients with diabetic nephropathy.
Diabetic Nephropathies
Motor and memory testing of long-lived pregnancy-associated plasma protein--a knock-out mice.
Diabetic Nephropathies
Neutrophil proteinase 3 induces diabetes in a mouse model of glucose tolerance.
Diabetic Nephropathies
Plasminogen activator inhibitor-1 antisense oligodeoxynucleotides abrogate mesangial fibronectin accumulation.
Diabetic Nephropathies
Protease activated receptor 2 in diabetic nephropathy: a double edged sword.
Diabetic Nephropathies
Proteases and protease inhibitors of urinary extracellular vesicles in diabetic nephropathy.
Diabetic Nephropathies
Proteomic and metabolomic characterization of streptozotocin-induced diabetic nephropathy in TIMP3-deficient mice.
Diabetic Nephropathies
The role of megsin, a serine protease inhibitor, in diabetic mesangial matrix accumulation.
Diabetic Neuropathies
Chronic hyperglycemia impairs mitochondrial unfolded protein response and precipitates proteotoxicity in experimental diabetic neuropathy: focus on LonP1 mediated mitochondrial regulation.
Diabetic Retinopathy
Altered mRNA levels of antioxidant enzymes in pre-apoptotic pericytes from human diabetic retinas.
Diabetic Retinopathy
Caspase-14 suppresses GCM1 acetylation and inhibits placental cell differentiation.
Diabetic Retinopathy
Differential expression of vitreous proteins in proliferative diabetic retinopathy.
Diabetic Retinopathy
High Glucose Induced Differential Expression of Lysyl Oxidase and Its Isoform in ARPE-19 Cells.
Diabetic Retinopathy
Photoreceptor Cell Calcium Dysregulation and Calpain Activation Promote Pathogenic Photoreceptor Oxidative Stress and Inflammation in Prodromal Diabetic Retinopathy.
Diabetic Retinopathy
Pigment-epithelium-derived factor down regulates hyperglycemia-induced apoptosis via PI3K/Akt activation in goat retinal pericytes.
DiGeorge Syndrome
Cloning and characterization of a novel human ubiquitin-specific protease, a homologue of murine UBP43 (Usp18).
Digestive System Diseases
Prospective, Open-Label Comparative Study of Liver Toxicity in an Unselected Population of HIV-Infected Patients Treated for the First Time with Efavirenz or Nevirapine.
Digestive System Neoplasms
Nafamostat Mesilate Enhances the Radiosensitivity and Reduces the Radiation-Induced Invasive Ability of Colorectal Cancer Cells.
Diphtheria
Cleavage of pseudomonas exotoxin and diphtheria toxin by a furin-like enzyme prepared from beef liver.
Diphtheria
Comparison of the apoptosis-inducing abilities of various protein synthesis inhibitors in U937 cells.
Diphtheria
Identification of inhibitors using a cell-based assay for monitoring Golgi-resident protease activity.
Diphtheria
Membrane interactions of diphtheria toxin analyzed using in vitro synthesized mutants.
Disseminated Intravascular Coagulation
A case of peripheral T-cell lymphoma presenting with acute liver failure.
Disseminated Intravascular Coagulation
Activation of prothrombin by ASP, a serine protease released from Aeromonas sobria.
Disseminated Intravascular Coagulation
Additional mechanisms of nafamostat mesilate-associated hyperkalaemia.
Disseminated Intravascular Coagulation
An anti-coagulation agent Futhan preferentially targets GABA(A) receptors in lungepithelia: implication in treating asthma.
Disseminated Intravascular Coagulation
Anti-tryptase treatment using nafamostat mesilate has a therapeutic effect on experimental colitis.
Disseminated Intravascular Coagulation
Assay with chromogenic substrates of in vivo activated proteases.
Disseminated Intravascular Coagulation
Auxiliary activation of the complement system and its importance for the pathophysiology of clinical conditions.
Disseminated Intravascular Coagulation
Benefit profile of anticoagulant therapy in sepsis: a nationwide multicentre registry in Japan.
Disseminated Intravascular Coagulation
Change in the acid protease activity in plasma of patients with disseminated intravascular coagulation.
Disseminated Intravascular Coagulation
Comparison of Danaparoid Sodium and Synthetic Protease Inhibitors for the Treatment of Disseminated Intravascular Coagulation Associated with Hematological Malignancies: A Retrospective Analysis.
Disseminated Intravascular Coagulation
Comparison of gabexate mesilate and nafamostat mesilate for disseminated intravascular coagulation associated with hematological malignancies.
Disseminated Intravascular Coagulation
Demonstration of granulocytic proteases in plasma of patients with acute leukemia and septicemia with coagulation defects.
Disseminated Intravascular Coagulation
Effect of nafamostat mesilate, a synthetic protease inhibitor, on tissue factor-factor VIIa complex activity.
Disseminated Intravascular Coagulation
Effects of antithrombin and gabexate mesilate on disseminated intravascular coagulation: a preliminary study.
Disseminated Intravascular Coagulation
Effects of FUT-175, a new synthetic protease inhibitor on endotoxin-induced disseminated intravascular coagulation in rats.
Disseminated Intravascular Coagulation
Effects of nafamostat mesilate on coagulopathy with chronic aortic dissection.
Disseminated Intravascular Coagulation
Gabexate mesilate, a synthetic protease inhibitor, attenuates carbon tetrachloride-induced liver injury in rats.
Disseminated Intravascular Coagulation
Gabexate mesilate, a synthetic protease inhibitor, inhibits lipopolysaccharide-induced tumor necrosis factor-alpha production by inhibiting activation of both nuclear factor-kappaB and activator protein-1 in human monocytes.
Disseminated Intravascular Coagulation
Human Recombinant Antithrombin (ATryn(®)) Administration Improves Survival and Prevents Intravascular Coagulation After Intraportal Islet Transplantation in a Piglet Model.
Disseminated Intravascular Coagulation
Inhibition of prostasin secretion by serine protease inhibitors in the kidney.
Disseminated Intravascular Coagulation
Inhibitory effects of gabexate mesilate (FOY) on experimental DIC.
Disseminated Intravascular Coagulation
Is protease inhibitor a choice for the treatment of pre- or mild disseminated intravascular coagulation?
Disseminated Intravascular Coagulation
Isolation of recombinant human antithrombin isoforms by Cellufine Sulfate affinity chromatography.
Disseminated Intravascular Coagulation
Longer operative time is associated with higher risk of severe complications after percutaneous nephrolithotomy: Analysis of 1511 cases from a Japanese nationwide database.
Disseminated Intravascular Coagulation
Modulation of muscle protein metabolism in disseminated intravascular coagulation.
Disseminated Intravascular Coagulation
Nafamostat Mesylate Improved Survival Outcomes of Sepsis Patients Who Underwent Blood Purification: A Nationwide Registry Study in Japan.
Disseminated Intravascular Coagulation
Plasma von Willebrand factor proteolysis in patients with chronic myeloproliferative disorders: no possibility of ex vivo degradation by calcium-dependent proteases.
Disseminated Intravascular Coagulation
Plasmodium falciparum Malaria Complicated by Symmetrical Peripheral Gangrene, Bowel Ischemia, Repeated Candidemia, and Bacteraemia.
Disseminated Intravascular Coagulation
Prevention of the liquoid-induced consumption coagulopathy by the protease inhibitor aprotinin.
Disseminated Intravascular Coagulation
Protease Inhibitors: Candidate Drugs to Inhibit Severe Acute Respiratory Syndrome Coronavirus 2 Replication.
Disseminated Intravascular Coagulation
Protective effects of ONO-3307, a new synthetic protease inhibitor against experimental disseminated intravascular coagulation in rats.
Disseminated Intravascular Coagulation
Protective effects of urinary trypsin inhibitor on systemic inflammatory response induced by lipopolysaccharide.
Disseminated Intravascular Coagulation
Protective role of urinary trypsin inhibitor in acute lung injury induced by lipopolysaccharide.
Disseminated Intravascular Coagulation
Protective role of urinary trypsin inhibitor in lung expression of proinflammatory cytokines accompanied by lethal liver injury in mice.
Disseminated Intravascular Coagulation
Stability of gabexate mesilate products: Influence of the addition of mannitol.
Disseminated Intravascular Coagulation
Treatment of porcine sepsis with high-dose antithrombin III reduces tissue edema and effusion but does not increase risk for bleeding.
Disseminated Intravascular Coagulation
Urinary trypsin inhibitor as a therapeutic option for endotoxin-related inflammatory disorders.
Disseminated Intravascular Coagulation
Urinary trypsin inhibitor protects against liver injury and coagulation pathway dysregulation induced by lipopolysaccharide/D-galactosamine in mice.
Disseminated Intravascular Coagulation
Urinary trypsin inhibitor protects against systemic inflammation induced by lipopolysaccharide.
Disseminated Intravascular Coagulation
Use of a synthetic protease inhibitor for the treatment of L-asparaginase-induced acute pancreatitis complicated by disseminated intravascular coagulation.
Disseminated Intravascular Coagulation
[Coagulation and the general surgeon. Its physiology and laboratory tests]
Disseminated Intravascular Coagulation
[Effective use of camostat mesilate for chronic disseminated intravascular coagulation complicated by thoracoabdominal aortic aneurysm]
Disseminated Intravascular Coagulation
[Protease inhibitors and plasminogen in leukemia--with special reference to disseminated intravascular coagulation (author's transl)]
Disseminated Intravascular Coagulation
[Substantiation, tactics and effectiveness of frozen plasma-enzyme inhibitor therapy in septicemia and infectious-destructive processes]
Disseminated Intravascular Coagulation
[Synthetic protease inhibitors in the treatment of disseminated intravascular coagulation]
Disseminated Intravascular Coagulation
[The protease inhibitor treatment of the disseminated intravascular coagulation syndrome in patients with liver cirrhosis]
Distal Myopathies
Mdm muscular dystrophy: interactions with calpain 3 and a novel functional role for titin's N2A domain.
Diverticulitis
Collagenase-3 (MMP-13) expression by inflamed mucosa in inflammatory bowel disease.
Diverticulum
Alpha-1-antitrypsin deficiency (carrier) as possible risk factor for development of colonic diverticula. A multicentre prospective case-control study: the ALADDIN study.
Diverticulum
Ontogenetic Changes in Enzyme Distribution and Midgut Function in Developmental Stages of Penaeus setiferus (Crustacea, Decapoda, Penaeidae).
Down Syndrome
Alpha-1-antitrypsin protease inhibitor (Pi) phenotypes in Down's syndrome patients and their parents.
Down Syndrome
Clipsin, a chymotrypsin-like protease in rat brain which is irreversibly inhibited by alpha-1-antichymotrypsin.
Down Syndrome
Developmental and aging changes in the expression of amyloid precursor protein in Down syndrome brains.
Down Syndrome
High expression on Kunitz-type protease inhibitor-containing substances in the cerebral vessels of patients with Down syndrome.
Down Syndrome
Pattern recognition receptors acting in innate immune system of shrimp against pathogen infections.
Down Syndrome
Protease nexin-II (amyloid beta-protein precursor): a platelet alpha-granule protein.
Drug Eruptions
Management of Refractory Telaprevir-Induced Dermatitis Using Oral Corticosteroids.
Drug Hypersensitivity Syndrome
Raltegravir-induced Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) syndrome - Implications for clinical practice and patient safety.
Drug-Related Side Effects and Adverse Reactions
Adverse drug reactions to protease inhibitors.
Drug-Related Side Effects and Adverse Reactions
Clinical update: impact of HIV protease inhibitors on the treatment of HIV-infected tuberculosis patients with rifampin.
Drug-Related Side Effects and Adverse Reactions
Cost of Adverse Drug Reactions (ADR) with Protease Inhibitors in the Treatment of Hepatitis C in the Health System of Extremadura (SES).
Drug-Related Side Effects and Adverse Reactions
Drug-drug interactions between antiretroviral and immunosuppressive agents in HIV-infected patients after solid organ transplantation: a review.
Drug-Related Side Effects and Adverse Reactions
Ethnogeographic and inter-individual variability of human ABC transporters.
Drug-Related Side Effects and Adverse Reactions
Highly active antiretroviral therapy in a large urban clinic: risk factors for virologic failure and adverse drug reactions.
Drug-Related Side Effects and Adverse Reactions
Immune reconstitution inflammatory syndrome: a report of TB-IRIS after switching from efavirenz to dolutegravir.
Drug-Related Side Effects and Adverse Reactions
Incidence of and risk factors for adverse drug reactions in a prospective cohort of HIV-infected adults initiating protease inhibitor-containing therapy.
Drug-Related Side Effects and Adverse Reactions
Incidence of atazanavir- associated adverse drug reactions in second -line drugs treated south Indian HIV-1 infected patients.
Drug-Related Side Effects and Adverse Reactions
Low body weight and type of protease inhibitor predict discontinuation and treatment-limiting adverse drug reactions among HIV-infected patients starting a protease inhibitor regimen: consistent results from a randomized trial and an observational cohort.
Drug-Related Side Effects and Adverse Reactions
Natural History, Risk Factors And Management Of Hepatitis C After Liver Transplantation.
Drug-Related Side Effects and Adverse Reactions
Nucleoside reverse transcriptase inhibitors are able and protease inhibitors unable to induce the tolerogenic molecule HLA-G1 on monocytes from HIV-1 infected patients.
Drug-Related Side Effects and Adverse Reactions
Small molecule inhibitor of HIV-1 nuclear import suppresses HIV-1 replication in human lymphoid tissue ex vivo: a potential addition to current anti-HIV drug repertoire.
Drug-Related Side Effects and Adverse Reactions
Usefulness of therapeutic drug monitoring of antiretrovirals in routine clinical practice.
Dry Eye Syndromes
A novel serine protease inhibitor as potential treatment for dry eye syndrome and ocular inflammation.
Dry Eye Syndromes
Desiccating Stress-Induced MMP Production and Activity Worsens Wound Healing in Alkali-Burned Corneas.
Dry Eye Syndromes
Differential Effects of Dexamethasone and Doxycycline on Inflammation and MMP Production in Alkali-Burned Corneas Associated with Dry Eye.
Dry Eye Syndromes
Serine protease inhibitor A3K suppressed the formation of ocular surface squamous metaplasia in a mouse model of experimental dry eye.
Dry Eye Syndromes
Tear Proteases and Protease Inhibitors: Potential Biomarkers and Disease Drivers in Ocular Surface Disease.
Duane Retraction Syndrome
Carboxypeptidase A6 in zebrafish development and implications for VIth cranial nerve pathfinding.
Duodenal Obstruction
Continuous regional application of protease inhibitor in the treatment of acute pancreatitis. An experimental study using closed duodenal obstruction model in dogs.
Duodenal Ulcer
Impaired fibrinolysis and increased protease levels in gastric and duodenal mucosa of patients with active duodenal ulcer.
Duodenal Ulcer
[Blood protease inhibitors in children with duodenal ulcer and gastroduodenitis during health resort therapy]
Dysentery, Bacillary
Calpain activation by the Shigella flexneri effector VirA regulates key steps in the formation and life of the bacterium's epithelial niche.
Dysentery, Bacillary
Myristoylome profiling reveals a concerted mechanism of ARF GTPase deacylation by the bacterial protease IpaJ.
Dysgeusia
[Implications of antiretroviral therapy in oral medicine--a review of literature]
Dysgeusia
[Side-effects of pegylated interferon plus ribavirin therapy with or without protease inhibitor direct acting antiviral agents during treatment of chronic hepatitis C virus infection].
Dyslipidemias
Abnormalities in apolipoprotein and lipid levels in an HIV-infected Brazilian population under different treatment profiles: the relevance of apolipoprotein E genotypes and immunological status.
Dyslipidemias
Acute Myocardial Infarction in a 34-Year-Old HIV-Positive Female Patient While Undergoing Active Antiretroviral Therapy Containing a Protease Inhibitor.
Dyslipidemias
Alterations in thigh subcutaneous adipose tissue gene expression in protease inhibitor-based highly active antiretroviral therapy.
Dyslipidemias
Antiretroviral therapy as a cardiovascular disease risk factor: fact or fiction? A review of clinical and surrogate outcome studies.
Dyslipidemias
Antiretroviral therapy-associated dyslipidemia in patients from a reference center in Brazil.
Dyslipidemias
Antiviral activity and clinical efficacy of atazanavir in HIV-1-infected patients: a review.
Dyslipidemias
Association of Clinical and Therapeutic Factors with Incident Dyslipidemia in a Cohort of Human Immunodeficiency Virus-Infected and Non-Infected Adults: 1994-2011.
Dyslipidemias
Associations among Race/Ethnicity, ApoC-III Genotypes, and Lipids in HIV-1-Infected Individuals on Antiretroviral Therapy.
Dyslipidemias
Atazanavir--a once-daily HIV protease inhibitor that does not cause dyslipidemia in newly treated patients: results from two randomized clinical trials.
Dyslipidemias
Atherogenic dyslipidemia in HIV-infected individuals treated with protease inhibitors. The Swiss HIV Cohort Study.
Dyslipidemias
AVASCULAR NECROSIS OF THE FEMORAL HEAD IN HIV-INFECTED PATIENTS: PRELIMINARY RESULTS FROM SURGICAL TREATMENT FOR CERAMIC-CERAMIC JOINT REPLACEMENT.
Dyslipidemias
Cardiovascular risk and dyslipidemia among persons living with HIV: a review.
Dyslipidemias
Cardiovascular risks associated with protease inhibitors for the treatment of HIV.
Dyslipidemias
CD36 overexpression in ritonavir-treated THP-1 cells is reversed by alpha-tocopherol.
Dyslipidemias
Change to atazanavir/ritonavir treatment improves lipids but not endothelial function in patients on stable antiretroviral therapy.
Dyslipidemias
Clinical characteristics of HIV-1-infected patients with high levels of plasma interferon-?: a multicenter observational study.
Dyslipidemias
Comparison of once-daily atazanavir with efavirenz, each in combination with fixed-dose zidovudine and lamivudine, as initial therapy for patients infected with HIV.
Dyslipidemias
Cross-sectional study of endothelial function in HIV-infected patients in Brazil.
Dyslipidemias
Dyslipidemia in an Asian population after treatment for two years with protease inhibitor-containing regimens.
Dyslipidemias
Dyslipidemia in HIV-Infected Children and Adolescents on Antiretroviral Therapy Receiving Care at Kilimanjaro Christian Medical Centre in Tanzania: A Cross-Sectional Study.
Dyslipidemias
Dyslipidemia, Diet and Physical Exercise in Children on Treatment With Antiretroviral Medication in El Salvador: A Cross-sectional Study.
Dyslipidemias
Effect of atazanavir and ritonavir on the differentiation and adipokine secretion of human subcutaneous and omental preadipocytes.
Dyslipidemias
Effects of ezetimibe on cholesterol metabolism in HIV-infected patients with protease inhibitor-associated dyslipidemia: a single-arm intervention trial.
Dyslipidemias
Effects of Pitavastatin on Lipid Profiles in HIV-Infected Patients with Dyslipidemia and Receiving Atazanavir/Ritonavir: A Randomized, Double-Blind, Crossover Study.
Dyslipidemias
Effects of troglitazone on insulin sensitivity in HIV-infected patients with protease inhibitor-associated diabetes mellitus.
Dyslipidemias
Endoplasmic reticulum stress links dyslipidemia to inhibition of proteasome activity and glucose transport by HIV protease inhibitors.
Dyslipidemias
Exercise Training in HIV-1-Infected Individuals with Dyslipidemia and Lipodystrophy.
Dyslipidemias
Genetic markers associated to dyslipidemia in HIV-infected individuals on HAART.
Dyslipidemias
Glyceroneogenesis is inhibited through HIV protease inhibitor-induced inflammation in human subcutaneous but not visceral adipose tissue.
Dyslipidemias
Gynecomastia, lipodystrophy syndrome, and dyslipidemia occurring or worsening during antiretroviral regimens other than protease inhibitor-based ones.
Dyslipidemias
Highly active antiretroviral therapy-associated metabolic syndrome and cardiovascular risk.
Dyslipidemias
HIV protease inhibitors promote atherosclerotic lesion formation independent of dyslipidemia by increasing CD36-dependent cholesteryl ester accumulation in macrophages.
Dyslipidemias
Impact of cocaine use on protease inhibitor-associated dyslipidemia in HIV-infected adults.
Dyslipidemias
Impact of HIV and highly active antiretroviral therapy on leukocyte adhesion molecules, arterial inflammation, dyslipidemia, and atherosclerosis.
Dyslipidemias
Improvement in insulin sensitivity and dyslipidemia in protease inhibitor-treated adult male patients after switch to atazanavir/ritonavir.
Dyslipidemias
Improvement of HAART-associated insulin resistance and dyslipidemia after replacement of protease inhibitors with abacavir.
Dyslipidemias
Incidence of dyslipidemia in people with HIV who are treated with integrase inhibitors versus other antiretroviral agents.
Dyslipidemias
Inhibitory effects of IFN-gamma on HIV-1 replication in latently infected cells.
Dyslipidemias
Leptin replacement therapy but not dietary polyunsaturated fatty acid alleviates HIV protease inhibitor-induced dyslipidemia and lipodystrophy in mice.
Dyslipidemias
Lipid profiles of Thai adult HIV-infected patients receiving protease inhibitors.
Dyslipidemias
Long-term cardiovascular risk with protease inhibitors and management of the dyslipidemia.
Dyslipidemias
Marked dyslipidemia in human immunodeficiency virus-infected children on protease inhibitor-containing antiretroviral therapy.
Dyslipidemias
Mechanisms of lipid elevations associated with the treatment of patients with HIV infection.
Dyslipidemias
Metabolic and cardiovascular complications of highly active antiretroviral therapy for HIV infection.
Dyslipidemias
Metabolic Complications among Korean Patients with HIV Infection: The Korea HIV/AIDS Cohort Study.
Dyslipidemias
Metabolic complications and treatment of perinatally HIV-infected children and adolescents.
Dyslipidemias
Metabolic response to a C-glucose load in human immunodeficiency virus patients before and after antiprotease therapy.
Dyslipidemias
No impairment of endothelial function or insulin sensitivity with 4 weeks of the HIV protease inhibitors atazanavir or lopinavir-ritonavir in healthy subjects without HIV infection: a placebo-controlled trial.
Dyslipidemias
Persistent dyslipidemia in HIV-infected individuals switched from a protease inhibitor-containing to an efavirenz-containing regimen.
Dyslipidemias
Prevalence and correlates of dyslipidemia in HIV positive and negative adults in Western Kenya: A cross-sectional study.
Dyslipidemias
Protease Inhibitor-Associated Dyslipidemia in HIV-Infected Patients Is Strongly Influenced by the APOA5-1131T->C Gene Variation.
Dyslipidemias
Reviewing the cardiovascular complications of HIV infection after the introduction of highly active antiretroviral therapy.
Dyslipidemias
Rosuvastatin versus pravastatin in dyslipidemic HIV-1-infected patients receiving protease inhibitors: a randomized trial.
Dyslipidemias
Severe rhabdomyolysis due to rosuvastatin in a liver transplant subject with human immunodeficiency virus and immunosuppressive therapy-related dyslipidemia.
Dyslipidemias
Short-Term Efficacy and Safety of Adding Ezetimibe to Current Regimen of Lipid-Lowering Drugs in Human Immunodeficiency Virus-Infected Thai Patients Treated with Protease Inhibitors.
Dyslipidemias
Synthetic protease inhibitor camostat prevents and reverses dyslipidemia, insulin secretory defects, and histological abnormalities of the pancreas in genetically obese and diabetic rats.
Dyslipidemias
The nurse practitioner's role in managing dyslipidemia and other cardiovascular risk factors in HIV-infected patients: impact of antiretroviral therapy.
Dyslipidemias
The SWITCHMRK studies: substitution of lopinavir/ritonavir with raltegravir in HIV-positive individuals.
Dyslipidemias
The therapeutic potential of PCSK9 inhibition in primary dyslipidemia, the example from SAR236553/REGN727 McKenney JM, Koren MJ, Kereiakes DJ, Hanotin C, Ferrand AC, Stein EA. Safety and efficacy of a monoclonal antibody to proprotein convertase Subtilisin/Kexin type 9 serine protease, SAR236553/REGN727, in patients with primary hypercholesterolemia receiving ongoing stable atorvastatin therapy. J Am Coll Cardiol 2012. [Epub ahead of print].
Dyslipidemias
Thiazolidinediones could improve endothelial dysfunction and risk of premature coronary heart disease in HIV-infected patients.
Dyslipidemias
Visceral adiposity, C-peptide levels, and low lipase activities predict HIV-dyslipidemia.
Dyslipidemias
[Abnormal body fat distribution and type of antiretroviral therapy as predictors of cardiovascular disease risk in HIV-infected patients]
Dyslipidemias
[Acute myocardial infarct in HIV-positive patients in treatment with protease inhibitors]
Dyslipidemias
[Efectiveness and safety of switching to raltegravir-based regimen in dyslipidemic HIV-infected patients receiving antiretroviral therapy at Arriaran Foundation].
Dyslipidemias
[High frequency of dyslipidemia in VIH-infected patients in aa peruvian public hospital].
Dyslipidemias
[Toxicogenetics of antiretroviral treatment (1): lipodystrophy, metabolic perturbations and atherosclerosis].
Dyspnea
Systemic cytokines, clinical and physiological changes in patients hospitalized for exacerbation of COPD.
Echinococcosis
A Comparison between the Effects of Albendazole and Mebendazole on the Enzymatic Activity of Excretory / Secretory Products of Echinococcus granulosus Protoscoleces in Vitro.
Echinococcosis
Alveolar hydatid cyst induced amyloid enhancing factor (AEF): physicochemical properties and abolition of AEF activity by serine protease inhibitors.
Echinococcosis
Kunitz type protease inhibitor EgKI-1 from the canine tapeworm Echinococcus granulosus as a promising therapeutic against breast cancer.
Ectopia Lentis
Unusual life cycle and impact on microfibril assembly of ADAMTS17, a secreted metalloprotease mutated in genetic eye disease.
Ectromelia, Infectious
The Ectromelia Virus SPI-2 Protein Causes Lethal Mousepox by preventing NK Cell Responses.
Eczema
Analysis of the individual and aggregate genetic contributions of previously identified serine peptidase inhibitor Kazal type 5 (SPINK5), kallikrein-related peptidase 7 (KLK7), and filaggrin (FLG) polymorphisms to eczema risk.
Ehlers-Danlos Syndrome
Ehlers-Danlos syndrome IV due to a novel defect in type III procollagen.
Ehlers-Danlos Syndrome
Ehlers-Danlos syndrome type VIIA and VIIB result from splice-junction mutations or genomic deletions that involve exon 6 in the COL1A1 and COL1A2 genes of type I collagen.
Ehlers-Danlos Syndrome
Isolation of collagen from the skins of Ehlers-Danlos syndrome-affected dogs by acetic acid extraction and pepsin digestion.
Elephantiasis, Filarial
Antibodies to microfilarial sheath in bancroftian filariasis--prevalence and characterization.
Elephantiasis, Filarial
Identification of 38kDa Brugia malayi microfilarial protease as a vaccine candidate for lymphatic filariasis.
Embolic Stroke
Activated protein C inhibits tissue plasminogen activator-induced brain hemorrhage.
Encephalitis
Cerebrospinal fluid viral escape and acute encephalitis in a patient on boosted protease inhibitor monotherapy.
Encephalitis
Crystal structure of a novel conformational state of the Flavivirus NS3 protein: Implications for Polyprotein Processing and Viral Replication.
Encephalitis
Drug monitoring of pyrimethamine during maintenance therapy of toxoplasmic encephalitis in patients with advanced HIV infection during HAART.
Encephalitis
Expression of matrix metalloproteinases and their tissue inhibitor during viral encephalitis.
Encephalitis
Improvement of the purification of Saint Louis encephalitis virus NS2B-NS3 recombinant protease expressed in Escherichia coli.
Encephalitis
Maintenance therapy with cotrimoxazole for toxoplasmic encephalitis in the era of highly active antiretroviral therapy.
Encephalitis
Protease treatment and chemical crosslinking of a flavivirus: tick borne encephalitis virus.
Encephalitis
Signal peptidase cleavage at the flavivirus C-prM junction: dependence on the viral NS2B-3 protease for efficient processing requires determinants in C, the signal peptide, and prM.
Encephalitis
Solid-phase synthesis and screening of a library of C-terminal arginine peptide aldehydes against Murray Valley encephalitis virus protease.
Encephalitis
THE action of TH17 cells on blood brain barrier in multiple sclerosis and experimental autoimmune encephalomyelitis.
Encephalitis
The effect of lopinavir/ritonavir and lopinavir/ritonavir loaded PLGA nanoparticles on experimental toxoplasmosis.
Encephalitis
Unexpected altered specificity is responsible for St. Louis encephalitis virus recombinant protease autoproteolysis.
Encephalitis, Japanese
A monoclonal antibody against PrM/M protein of Japanese encephalitis virus.
Encephalitis, Japanese
Abscisic acid and aloe-emodin against NS2B-NS3A protease of Japanese encephalitis virus.
Encephalitis, Japanese
Crystal structure of the catalytic domain of Japanese encephalitis virus NS3 helicase/nucleoside triphosphatase at a resolution of 1.8 A.
Encephalitis, Japanese
Enzymatic analysis of recombinant Japanese encephalitis virus NS2B(H)-NS3pro protease with fluorogenic model peptide substrates.
Encephalitis, Japanese
Japanese encephalitis virus nonstructural protein NS3 has RNA binding and ATPase activities.
Encephalitis, Japanese
Molecular interaction of the antiviral compound CW?33 and its analogues with the NS2B?NS3 protease of the Japanese encephalitis virus.
Encephalitis, Japanese
Monoclonal Antibody That Inhibits Cleavage Activity of Japanese Encephalitis Virus NS3.
Encephalitis, Japanese
Structure-based virtual screening for novel inhibitors of Japanese encephalitis virus NS3 helicase/nucleoside triphosphatase.
Encephalitis, Japanese
Upregulation of signalase processing and induction of prM-E secretion by the flavivirus NS2B-NS3 protease: roles of protease components.
Encephalitis, St. Louis
Improvement of the purification of Saint Louis encephalitis virus NS2B-NS3 recombinant protease expressed in Escherichia coli.
Encephalitis, Tick-Borne
Changing the protease specificity for activation of a flavivirus, tick-borne encephalitis virus.
Encephalitis, Tick-Borne
High-Throughput Fluorescent Assay for Inhibitor Screening of Proteases from RNA Viruses.
Encephalitis, Tick-Borne
NS2B/NS3 protease: allosteric effect of mutations associated with the pathogenicity of tick-borne encephalitis virus.
Encephalitis, Tick-Borne
Protease treatment and chemical crosslinking of a flavivirus: tick borne encephalitis virus.
Encephalitis, Tick-Borne
Site-directed mutagenesis of the tick-borne encephalitis virus NS3 gene reveals the putative serine protease domain of the NS3 protein.
Encephalitis, Tick-Borne
Targeting the NS2B-NS3 protease of tick-borne encephalitis virus with pan-flaviviral protease inhibitors.
Encephalomalacia
Clinical and magnetic resonance imaging regression of progressive multifocal leukoencephalopathy in an AIDS patient after intensive antiretroviral therapy.
Encephalomalacia
Immunoreactive A4 and gamma-trace peptide colocalization in amyloidotic arteriolar lesions in brains of patients with Alzheimer's disease.
Encephalomyelitis
Altered proteolytic events in experimental autoimmune encephalomyelitis discovered by iTRAQ shotgun proteomics analysis of spinal cord.
Encephalomyelitis
Differential expression of protease M/neurosin in oligodendrocytes and their progenitors in an animal model of multiple sclerosis.
Encephalomyelitis
Increased KPI containing amyloid precursor protein in experimental autoimmune encephalomyelitis brains.
Encephalomyelitis
MALT1 inhibitors prevent the development of DSS-induced experimental colitis in mice via inhibiting NF-?B and NLRP3 inflammasome activation.
Encephalomyelitis
Prevention of acute autoimmune encephalomyelitis and abrogation of relapses in murine models of multiple sclerosis by the protease inhibitor D-penicillamine.
Encephalomyelitis
Protease activated receptor-1 antagonist ameliorates the clinical symptoms of experimental autoimmune encephalomyelitis via inhibiting breakdown of blood-brain barrier.
Encephalomyelitis
The protease inhibitor, Bowman-Birk Inhibitor, suppresses experimental autoimmune encephalomyelitis: a potential oral therapy for multiple sclerosis.
Encephalomyelitis
Thymic-Specific Serine Protease Limits Central Tolerance and Exacerbates Experimental Autoimmune Encephalomyelitis.
Encephalomyelitis
Time-dependent increases in protease activities for neuronal apoptosis in spinal cords of Lewis rats during development of acute experimental autoimmune encephalomyelitis.
Encephalomyelitis, Autoimmune, Experimental
Altered proteolytic events in experimental autoimmune encephalomyelitis discovered by iTRAQ shotgun proteomics analysis of spinal cord.
Encephalomyelitis, Autoimmune, Experimental
Differential expression of protease M/neurosin in oligodendrocytes and their progenitors in an animal model of multiple sclerosis.
Encephalomyelitis, Autoimmune, Experimental
Early detection of thrombin activity in neuroinflammatory disease.
Encephalomyelitis, Autoimmune, Experimental
Increased KPI containing amyloid precursor protein in experimental autoimmune encephalomyelitis brains.
Encephalomyelitis, Autoimmune, Experimental
MALT1 inhibitors prevent the development of DSS-induced experimental colitis in mice via inhibiting NF-?B and NLRP3 inflammasome activation.
Encephalomyelitis, Autoimmune, Experimental
Observations on the effects of protease inhibitors on the suppression of experimental allergic encephalomyelitis.
Encephalomyelitis, Autoimmune, Experimental
Protease activated receptor-1 antagonist ameliorates the clinical symptoms of experimental autoimmune encephalomyelitis via inhibiting breakdown of blood-brain barrier.
Encephalomyelitis, Autoimmune, Experimental
Suppression of experimental allergic encephalomyelitis (EAE) with liposome-encapsulated protease inhibitor: therapy through the blood-brain barrier.
Encephalomyelitis, Autoimmune, Experimental
Suppressive effect of camostat mesilate (FOY 305) on acute experimental allergic encephalomyelitis (EAE).
Encephalomyelitis, Autoimmune, Experimental
The autolytic regulation of human kallikrein-related peptidase 6.
Encephalomyelitis, Autoimmune, Experimental
The protease inhibitor, Bowman-Birk Inhibitor, suppresses experimental autoimmune encephalomyelitis: a potential oral therapy for multiple sclerosis.
Encephalomyelitis, Autoimmune, Experimental
Thymic-Specific Serine Protease Limits Central Tolerance and Exacerbates Experimental Autoimmune Encephalomyelitis.
Encephalomyelitis, Autoimmune, Experimental
Time-dependent increases in protease activities for neuronal apoptosis in spinal cords of Lewis rats during development of acute experimental autoimmune encephalomyelitis.
Encephalomyelitis, Autoimmune, Experimental
Tissue-type plasminogen activator is a regulator of monocyte diapedesis through the brain endothelial barrier.
Encephalomyelitis, Venezuelan Equine
Specificity Studies of the Venezuelan Equine Encephalitis Virus Non-Structural Protein 2 Protease Using Recombinant Fluorescent Substrates.
Encephalomyelitis, Venezuelan Equine
Structural basis for substrate specificity of alphavirus nsP2 proteases.
Endocarditis
AhrC and Eep Are Biofilm Infection-Associated Virulence Factors in Enterococcus faecalis.
Endocarditis
Effect of mucin and glucose on proteolytic and glycosidic activities of Streptococcus oralis.
Endocarditis
Fsr-independent production of protease(s) may explain the lack of attenuation of an Enterococcus faecalis fsr mutant versus a gelE-sprE mutant in induction of endocarditis.
Endocarditis
Gelatinase contributes to the pathogenesis of endocarditis caused by Enterococcus faecalis.
Endocarditis
Modulation of glycosidase and protease activities by chemostat growth conditions in an endocarditis strain of Streptococcus sanguis.
Endocarditis
Role of vegetation-associated protease activity in valve destruction in human infective endocarditis.
Endocarditis, Subacute Bacterial
Protease production by Streptococcus sanguis associated with subacute bacterial endocarditis.
Endometrial Hyperplasia
Endometrial hyperplasia-related inflammation: its role in the development and progression of endometrial hyperplasia.
Endometrial Neoplasms
Expression of protease activated receptor-2 related to angiogenesis in tumor advancement of uterine endometrial cancers.
Endometrial Neoplasms
Expression of the serine protease hepsin and clinical outcome of human endometrial cancer.
Endometrial Neoplasms
Identification of HSPA8 as a candidate biomarker for endometrial carcinoma by using iTRAQ-based proteomic analysis.
Endometrial Neoplasms
Immunohistochemical detection of p53 overexpression in formalin-fixed, paraffin-embedded sections of endometrial carcinoma.
Endometrial Neoplasms
Lysosomal protease cathepsin D is a prognostic marker in endometrial cancer.
Endometrial Neoplasms
Malignant cell-specific gelatinase activity in human endometrial carcinoma.
Endometrial Neoplasms
MiR-148b functions as a tumor suppressor by targeting endoplasmic reticulum metallo protease 1 in human endometrial cancer cells.
Endometrial Neoplasms
Progesterone receptor structure and protease activity in primary human endometrial carcinoma.
Endometrial Neoplasms
The pattern of Protease Activated Receptor 1 (PAR1) expression in endometrial carcinoma.
Endometriosis
Association of protease activity against IGFBP-3 with peritoneal fluid mitogens: possible implications for the ectopic growth of endometrial cells in women with endometriosis.
Endometriosis
Chemotaxis of macrophages by a peritoneal fluid protein in women with endometriosis.
Endometriosis
Elevated Peritoneal Fluid TNF-? Incites Ovarian Early Growth Response Factor 1 Expression and Downstream Protease Mediators: A Correlation With Ovulatory Dysfunction in Endometriosis.
Endometriosis
Expression of CD44s, vascular endothelial growth factor, matrix metalloproteinase-2 and Ki-67 in peritoneal, rectovaginal and ovarian endometriosis.
Endometriosis
Expression of secretory leukocyte protease inhibitor in women with endometriosis.
Endometriosis
Granzyme B levels and granzyme B polymorphisms in peripheral blood of patients with endometriosis: a preliminary study.
Endometriosis
Increased concentrations of secretory leukocyte protease inhibitor in peritoneal fluid of women with endometriosis.
Endometriosis
Insulin-like growth factors (IGFs), IGF-binding proteins (IGFBPs), and IGFBP-3 protease activity in the peritoneal fluid of patients with and without endometriosis.
Endometriosis
Multiplexed protease activity assay for low-volume clinical samples using droplet-based microfluidics and its application to endometriosis.
Endometriosis
Protein, progesterone, and protease inhibitors in uterine and peritoneal fluids of women with endometriosis.
Endometriosis
Secretory leukocyte protease inhibitor in ovarian endometriomas following GnRH agonist therapy.
Endometriosis
Targeting autocrine HB-EGF signaling with specific ADAM12 inhibition using recombinant ADAM12 prodomain.
Endometriosis
USP10 promotes proliferation and migration and inhibits apoptosis of endometrial stromal cells in endometriosis through activating the Raf-1/MEK/ERK pathway.
Endometriosis
[Genetic aspects of endometriosis: features of the distribution of polymorphic gene frequencies]
Endometriosis
[Specific features of protease and antiprotease activity of blood in women with external endometriosis]
Endometritis
The In Vitro Inhibitory Effect of Sivelestat on Elastase Induced Collagen and Metallopeptidase Expression in Equine Endometrium.
endopeptidase la deficiency
A new pathway encompassing calpain 3 and its newly identified substrate cardiac ankyrin repeat protein is involved in the regulation of the nuclear factor-?B pathway in skeletal muscle.
endopeptidase la deficiency
Aetiology and pathogenesis of thrombotic thrombocytopenic purpura and haemolytic uraemic syndrome: the role of von Willebrand factor-cleaving protease.
endopeptidase la deficiency
Alkaline protease deficiency in the cr-1 (crisp) mutant of Neurospora crassa.
endopeptidase la deficiency
Assays of von Willebrand factor-cleaving protease: a test for diagnosis of familial and acquired thrombotic thrombocytopenic purpura.
endopeptidase la deficiency
ATPase and Protease Domain Movements in the Bacterial AAA+ Protease FtsH Are Driven by Thermal Fluctuations.
endopeptidase la deficiency
Autosomal recessive inheritance of von Willebrand factor-cleaving protease deficiency.
endopeptidase la deficiency
Biochemical and molecular characterisation of Tetrahymena thermophila extracellular cysteine proteases.
endopeptidase la deficiency
Contribution of normal and error-prone ribosomes to translational error formation in vivo.
endopeptidase la deficiency
Deficiency of von Willebrand factor-cleaving protease in familial and acquired thrombotic thrombocytopenic purpura.
endopeptidase la deficiency
Deletion of cysteine cathepsins B or L yields differential impacts on murine skin proteome and degradome.
endopeptidase la deficiency
Deletion of the mitochondrial Pim1/Lon protease in yeast results in accelerated aging and impairment of the proteasome.
endopeptidase la deficiency
Distorted secretory granule composition in mast cells with multiple protease deficiency.
endopeptidase la deficiency
Downregulation of mitochondrial lon protease impairs mitochondrial function and causes hepatic insulin resistance in human liver SK-HEP-1 cells.
endopeptidase la deficiency
Effect of Clp protease from Corynebacterium glutamicum on heterologous protein expression.
endopeptidase la deficiency
Efficient generation of recessive traits in diploid sake yeast by targeted gene disruption and loss of heterozygosity.
endopeptidase la deficiency
Establishment of Neurospora crassa as a host for heterologous protein production using a human antibody fragment as a model product.
endopeptidase la deficiency
Functional genetic mouse models: promising tools for investigation of the proteolytic internet.
endopeptidase la deficiency
Highly Contingent Phenotypes of Lon Protease Deficiency in Escherichia coli upon Antibiotic Challenge.
endopeptidase la deficiency
Identification and characterization of spdR mutations that bypass the BsgA protease-dependent regulation of developmental gene expression in Myxococcus xanthus.
endopeptidase la deficiency
IFAP syndrome is caused by deficiency in MBTPS2, an intramembrane zinc metalloprotease essential for cholesterol homeostasis and ER stress response.
endopeptidase la deficiency
Impaired axonal retrograde trafficking of the retromer complex augments lysosomal deficits in Alzheimer's disease neurons.
endopeptidase la deficiency
Impaired immunity and enhanced resistance to endotoxin in the absence of neutrophil elastase and cathepsin G.
endopeptidase la deficiency
Increased anxiety-like behavior in neuropsin (kallikrein-related peptidase 8) gene-deficient mice.
endopeptidase la deficiency
IS186 insertion at a hot spot in the lon promoter as a basis for lon protease deficiency of Escherichia coli B: identification of a consensus target sequence for IS186 transposition.
endopeptidase la deficiency
Loss of high-temperature requirement protein A2 protease activity induces mitonuclear imbalance via differential regulation of mitochondrial biogenesis in sarcopenia.
endopeptidase la deficiency
Lysosomal protease deficiency or substrate overload induces an oxidative-stress mediated STAT3-dependent pathway of lysosomal homeostasis.
endopeptidase la deficiency
Malt1 Protease Deficiency in Mice Disrupts Immune Homeostasis at Environmental Barriers and Drives Systemic T Cell-Mediated Autoimmunity.
endopeptidase la deficiency
Phage-assisted continuous evolution of proteases with altered substrate specificity.
endopeptidase la deficiency
Prolonged inhibition of von Willebrand factor-cleaving protease after splenectomy in a 22-year-old patient with acute and plasma refractory thrombotic thrombocytopenic purpura.
endopeptidase la deficiency
Prospective study on the behaviour of the metalloprotease ADAMTS13 and of von Willebrand factor after bone marrow transplantation.
endopeptidase la deficiency
Protease deficiency in plasma of patients with cystic fibrosis. Reduced reaction of 4-methylumbelliferylguanidinobenzoate with plasma of patients with cystic fibrosis.
endopeptidase la deficiency
Protective role of the mitochondrial Lon protease 1 in ochratoxin A-induced cytotoxicity in HEK293 cells.
endopeptidase la deficiency
Reaction of 4-methylumbelliferylguanidinobenzoate with proteases in plasma of patients with cystic fibrosis.
endopeptidase la deficiency
Regulation of extravascular coagulation and fibrinolysis by heparin-dependent mast cell chymase.
endopeptidase la deficiency
Specific protease deficiency in polymorphonuclear leukocytes of Chédiak-Higashi syndrome and beige mice.
endopeptidase la deficiency
Ten years of prophylactic treatment with fresh-frozen plasma in a child with chronic relapsing thrombotic thrombocytopenic purpura as a result of a congenital deficiency of von Willebrand factor-cleaving protease.
endopeptidase la deficiency
The combined action of mast cell chymase, tryptase and carboxypeptidase A3 protects against melanoma colonization of the lung.
endopeptidase la deficiency
The effects of intrinsic pathway protease deficiencies on plasminogen-deficient mice.
endopeptidase la deficiency
Thrombotic thrombocytopenic purpura--the role of ADAMTS13 assay in clinical practice.
endopeptidase la deficiency
TTP-like syndrome: novel concept and molecular pathogenesis of endotheliopathy-associated vascular microthrombotic disease.
endopeptidase la deficiency
von Willebrand factor-cleaving protease in thrombotic thrombocytopenic purpura and the hemolytic-uremic syndrome.
endopeptidase la deficiency
Yeast mutants with enhanced ability to secrete human lysozyme: isolation and identification of a protease-deficient mutant.
endopeptidase la deficiency
[High substitution value of pepsin in gastric protease deficiency.]
endopeptidase la deficiency
[Pathophysiology of thrombotic microangiopathies: current understanding]
endopeptidase la deficiency
[Von Willebrand factor as an intermediate between hemostasis and angiogenesis of tumor origin]
Endophthalmitis
Antibiotic susceptibility, cytotoxicity, and protease activity of viridans group streptococci causing endophthalmitis.
Endophthalmitis
Contribution of gelatinase, serine protease, and fsr to the pathogenesis of Enterococcus faecalis endophthalmitis.
Endophthalmitis
Contribution of secreted proteases to the pathogenesis of postoperative Enterococcus faecalis endophthalmitis.
Endophthalmitis
Secretory leukocyte protease inhibitor is an inducible antimicrobial peptide expressed in Staphylococcus aureus endophthalmitis.
Endotoxemia
Essential role of platelet activation via protease activated receptor 4 in tissue factor-initiated inflammation.
Endotoxemia
Hemodynamic, renal, and hormonal actions of aprotinin in an ovine model of septic shock.
Endotoxemia
Microcirculatory disturbances in endotoxin-induced disseminated intravascular coagulation. The effects of heparin and gabexate mesilate on locomotive and metabolic changes of neutrophils.
Endotoxemia
Pancreatic enzymes sustain systemic inflammation after an initial endotoxin challenge.
Endotoxemia
Secretory leukocyte protease inhibitor, an inhibitor of neutrophil activation, is elevated in serum in human sepsis and experimental endotoxemia.
Enteritis
Effect of carbohydrase and protease on growth performance and gut health of young broilers fed diets containing rye, wheat, and feather meal.
Enteritis
Evaluation of high dietary inclusion of distillers dried grains with solubles and supplementation of protease and xylanase in the diets of broiler chickens under necrotic enteritis challenge.
Enteritis
Saccharomyces boulardii protease inhibits the effects of Clostridium difficile toxins A and B in human colonic mucosa.
Enterocolitis
Protease Activity of Campylobacter jejuni HtrA Modulates Distinct Intestinal and Systemic Immune Responses in Infected Secondary Abiotic IL-10 Deficient Mice.
Enterotoxemia
Experimental production of hemorrhagic enterotoxemia by Clostridium perfringens type C in maturing lambs.
Enzootic Bovine Leukosis
Bovine leukemia virus protease: purification, chemical analysis, and in vitro processing of gag precursor polyproteins.
Enzootic Bovine Leukosis
Bovine leukemia virus: purification and characterization of the aspartic protease.
Enzootic Bovine Leukosis
Purification and characterization of human T-cell leukemia virus type I protease produced in Escherichia coli.
Eosinophilia
An Interleukin-33-Mast Cell-Interleukin-2 Axis Suppresses Papain-Induced Allergic Inflammation by Promoting Regulatory T Cell Numbers.
Eosinophilia
Characterization of exposure to low levels of viable Penicillium chrysogenum conidia and allergic sensitization induced by a protease allergen extract from viable P. Chrysogenum conidia in mice.
Eosinophilia
Epicutaneous vaccination with protease inhibitor-treated papain prevents papain-induced Th2-mediated airway inflammation without inducing Th17 in mice.
Eosinophilia
Functional role of kallikrein 5 and proteinase-activated receptor 2 in eosinophilic esophagitis.
Eosinophilia
IL-33-mediated innate response and adaptive immune cells contribute to maximum responses of protease allergen-induced allergic airway inflammation.
Eosinophilia
Interplay Between the IL-33/ST2 Axis and Bone Marrow ILC2s in Protease Allergen-Induced IL-5-Dependent Eosinophilia.
Eosinophilia
Predominance of IgG1 and IgG4 subclasses of anti-neutrophil cytoplasmic autoantibodies (ANCA) in patients with Wegener's granulomatosis and clinically related disorders.
Eosinophilia
Serine protease inhibitors nafamostat mesilate and gabexate mesilate attenuate allergen-induced airway inflammation and eosinophilia in a murine model of asthma.
Eosinophilia
Subcutaneous Allergic Sensitization to Protease Allergen Is Dependent on Mast Cells but Not IL-33: Distinct Mechanisms between Subcutaneous and Intranasal Routes.
Eosinophilic Esophagitis
The antiprotease SPINK7 serves as an inhibitory checkpoint for esophageal epithelial inflammatory responses.
Epidermolysis Bullosa Dystrophica
Protease inhibitor therapy for recessive dystrophic epidermolysis bullosa. In vitro effect and clinical trial with camostat mesylate.
Epidermolysis Bullosa Dystrophica
Retinoic acid inhibition of collagenase and gelatinase expression in human skin fibroblast cultures. Evidence for a dual mechanism.
Epidermolysis Bullosa Simplex
Generalized dominant epidermolysis bullosa simplex: decreased activity of a gelatinolytic protease in cultured fibroblasts as a phenotypic marker.
Epilepsy
Activation of CPP-32 protease in hippocampal neurons following ischemia and epilepsy.
Epilepsy
BACE1 elevation is associated with aberrant limbic axonal sprouting in epileptic CD1 mice.
Epilepsy
Characterization of PTZ-induced seizure susceptibility in a down syndrome mouse model that overexpresses CSTB.
Epilepsy
Crystal structure of aura virus capsid protease and its complex with dioxane: new insights into capsid-glycoprotein molecular contacts.
Epilepsy
Crystallization, high-resolution data collection and preliminary crystallographic analysis of Aura virus capsid protease and its complex with dioxane.
Epilepsy
The epilepsy, the protease inhibitor and the dodecamer: progressive myoclonus epilepsy, cystatin b and a 12-mer repeat expansion.
Epilepsy
Three-dimensional reconstruction of the S885A mutant of human mitochondrial Lon protease.
Epilepsy
Tissue Plasminogen Activator Expression Is Restricted to Subsets of Excitatory Pyramidal Glutamatergic Neurons.
Epilepsy
trans-Protease activity and structural insights into the active form of the alphavirus capsid protease.
Epilepsy, Temporal Lobe
BACE1 elevation is associated with aberrant limbic axonal sprouting in epileptic CD1 mice.
Epiretinal Membrane
The role of tryptase and anti-type II collagen antibodies in the pathogenesis of idiopathic epiretinal membranes.
Equine Infectious Anemia
Expression of functional protease and subviral particles by vaccinia virus containing equine infectious anaemia virus gag and 5' pol genes.
Equine Infectious Anemia
Expression of the protease gene of equine infectious anemia virus in Escherichia coli: formation of the mature processed enzyme and specific cleavage of the gag precursor.
Erectile Dysfunction
Mechanisms of pharmacokinetic and pharmacodynamic drug interactions associated with ritonavir-enhanced tipranavir.
Erectile Dysfunction
Risk factors for sexual and erectile dysfunction in HIV-infected men: the role of protease inhibitors.
Erysipelas
[The use of the kallikrein-kininogen system indices in the prognosis of the development of hemorrhagic erysipelas]
Erythema
Characterization of IgE-binding proteins in the salivary glands of Simulium nigrogilvum (Diptera: Simuliidae).
Erythema
Cloning of IgE-binding proteins from Simulium vittatum and their potential significance as allergens for equine insect bite hypersensitivity.
Erythema
Effect of serine-type protease of Candida spp. isolated from linear gingival erythema of HIV-positive children: critical factors in the colonization.
Erythema
Elastase 2 is expressed in human and mouse epidermis and impairs skin barrier function in Netherton syndrome through filaggrin and lipid misprocessing.
Esophageal Achalasia
Gelatinase B/Matrix Metalloproteinase-9 as Innate Immune Effector Molecule in Achalasia.
Esophageal Diseases
Natural history of HIV-associated esophageal disease in the era of protease inhibitor therapy.
Esophageal Neoplasms
Effect and mechanism of PAR-2 on the proliferation of esophageal cancer cells.
Esophageal Neoplasms
Inhibition of N-nitrosomethylbenzylamine-induced esophageal neoplasms by the Bowman-Birk protease inhibitor.
Esophageal Neoplasms
Molecular cloning and characterization of a novel esophageal cancer related gene.
Esophageal Neoplasms
NRAGE promotes cell proliferation by stabilizing PCNA in a ubiquitin-proteasome pathway in esophageal carcinomas.
Esophageal Neoplasms
Overexpression of asparaginyl endopeptidase is significant for esophageal carcinoma metastasis and predicts poor patient prognosis.
Esophageal Neoplasms
Relationship between secretory leukocyte protease inhibitor levels in bronchoalveolar lavage fluid and postoperative pulmonary complications in patients with esophageal cancer.
Esophageal Neoplasms
Ubiquitin-specific protease 4 improves the prognosis of the patients in esophageal cancer.
Esophageal Neoplasms
[Prokaryotic expression, purification and activity analysis of recombinant human serine protease inhibitor Hespintor Kazal Domain].
Esophageal Squamous Cell Carcinoma
ASO Author Reflections: Serine Protease 27 is a Novel Prognostic Indicator for Esophageal Squamous Cell Carcinoma with Preoperative Treatment.
Esophageal Squamous Cell Carcinoma
Epigenetic silencing of the PRSS3 putative tumor suppressor gene in non-small cell lung cancer.
Esophageal Squamous Cell Carcinoma
Expression Status of Serine Protease 27: A Prognostic Marker for Esophageal Squamous Cell Carcinoma Treated with Preoperative Chemotherapy/Chemoradiotherapy.
Esophageal Squamous Cell Carcinoma
Knockdown of ubiquitin-specific protease 14 (USP14) inhibits the proliferation and tumorigenesis in esophageal squamous cell carcinoma cells.
Esophageal Squamous Cell Carcinoma
Mammary serine protease inhibitor inhibits epithelial growth factor-induced epithelial-mesenchymal transition of esophageal carcinoma cells.
Esophageal Squamous Cell Carcinoma
Relationship between transmembrane serine protease expression and prognosis of esophageal squamous cell carcinoma.
Esophageal Squamous Cell Carcinoma
USP22 nuclear expression is significantly associated with progression and unfavorable clinical outcome in human esophageal squamous cell carcinoma.
Esophagitis, Peptic
A phase I study of high dose camostat mesylate in healthy adults provides a rationale to repurpose the TMPRSS2 inhibitor for the treatment of COVID-19.
Esophagitis, Peptic
Essential role of pepsin in pathogenesis of Acid reflux esophagitis in rats.
Esophagitis, Peptic
[Effects of FOY-305 on post-operative reflux esophagitis in rats (I). Effects of FOY-305 on reflux esophagitis after total gastrectomy in rats]
Essential Hypertension
Normal erythrocyte calpain I activity on membrane proteins under near-physiological conditions in patients with essential hypertension.
Essential Hypertension
[Allele polymorphism of genes coding proteasome subunits is associated with an enhanced risk for arterial hypertension in adolescents]
Essential Hypertension
[Protein C and plasma serine protease inhibitors in patients with essential hypertension]
Exanthema
Cloning and characterization of human ubiquitin-processing protease-43 from terminally differentiated human melanoma cells using a rapid subtraction hybridization protocol RaSH.
Exanthema
Dermatologic adverse effects of antiretroviral therapy: recognition and management.
Exanthema
Risk factors and occurrence of rash in HIV-positive patients not receiving nonnucleoside reverse transcriptase inhibitor: data from a randomized study evaluating use of protease inhibitors in nucleoside-experienced patients with very low CD4 levels (<50 cells/microL).
Exocrine Pancreatic Insufficiency
Study of a novel pancreatic enzyme replacement therapy in pancreatic insufficient subjects with cystic fibrosis.
Exostoses
Lathyrism: mini-review and a comment on the lack of effect of protease inhibitors on osteolathyrism.
Eye Diseases
A novel de novo CAPN5 mutation in a patient with inflammatory vitreoretinopathy, hearing loss, and developmental delay.
Factor VII Deficiency
Detection of two missense mutations and characterization of a repeat polymorphism in the factor VII gene (F7).
Factor XI Deficiency
Polyphosphate is a cofactor for the activation of factor XI by thrombin.
Factor XII Deficiency
Polyphosphate is a cofactor for the activation of factor XI by thrombin.
Factor XIII Deficiency
Bleeding disorder with abnormal wound healing, acid-soluble clots and normal factor XIII.
Familial Mediterranean Fever
Inactivation of interleukin-8 by the C5a-inactivating protease from serosal fluid.
Familial Mediterranean Fever
Plasma levels of the von Willebrand factor-cleaving protease in physiological and pathological conditions in children.
Fanconi Syndrome
Proximal renal tubular acidosis: a not so rare disorder of multiple etiologies.
Fanconi Syndrome
Tenofovir-associated Fanconi syndrome: review of the FDA adverse event reporting system.
Farmer's Lung
[Studies on the classification of thermophilic actinomycetes. IV. Determination of thermophilic Streptomyces hygroscopicus group]
Fasciculation
Extracellular serine protease neuropsin (KLK8) modulates neurite outgrowth and fasciculation of mouse hippocampal neurons in culture.
Fasciitis
Jak1-STAT3 Signals Are Essential Effectors of the USP6/TRE17 Oncogene in Tumorigenesis.
Fasciitis
Nodular Fasciitis With Malignant Morphology and a COL6A2-USP6 Fusion: A Case Report (of a 10-Year-old Boy).
Fasciitis
USP6 Confers Sensitivity to IFN-Mediated Apoptosis through Modulation of TRAIL Signaling in Ewing Sarcoma.
Fasciitis, Necrotizing
Decreased necrotizing fasciitis capacity caused by a single nucleotide mutation that alters a multiple gene virulence axis.
Fasciitis, Necrotizing
Group A Streptococcus Infection of the Nasopharynx Requires Proinflammatory Signaling through the Interleukin-1 Receptor.
Fasciitis, Necrotizing
The IL-8 protease SpyCEP/ScpC of group A Streptococcus promotes resistance to neutrophil killing.
Fascioliasis
The diagnosis of human fascioliasis by enzyme-linked immunosorbent assay (ELISA) using recombinant cathepsin L protease.
Fatty Liver
Coagulation-driven hepatic fibrosis requires protease activated receptor-1 (PAR-1) in a mouse model of TCDD-elicited steatohepatitis.
Fatty Liver
Improvement in liver steatosis after the switch from a ritonavir-boosted protease inhibitor to raltegravir in HIV-infected patients with non-alcoholic fatty liver disease.
Fatty Liver
Inhibiting Extracellular Cathepsin D Reduces Hepatic Steatosis in Sprague?Dawley Rats .
Fatty Liver
Is it appropriate to study blood ghrelin and obestatin in non-alcoholic fatty liver disease (NAFLD) without using protease inhibitors?
Fatty Liver
Leptin replacement therapy but not dietary polyunsaturated fatty acid alleviates HIV protease inhibitor-induced dyslipidemia and lipodystrophy in mice.
Fatty Liver
Proteolytic activity alterations resulting from force-feeding in Muscovy and Pekin ducks.
Fatty Liver
Ritonavir and Lopinavir Suppress RCE1 and CAAX Rab Proteins Sensitizing the Liver to Organelle Stress and Injury.
Fatty Liver
Tissue factor-deficiency and protease activated receptor-1-deficiency reduce inflammation elicited by diet-induced steatohepatitis in mice.
Fatty Liver
Ubiquitin-specific protease 22 ameliorates chronic alcohol-associated liver disease by regulating BRD4.
Febrile Neutropenia
The association between protease inhibitors and anal cancer outcomes in veterans living with HIV treated with definitive chemoradiation: a retrospective study.
Feline Acquired Immunodeficiency Syndrome
Response of feline immunodeficiency virus (FIV) to tipranavir may provide new clues for development of broad-based inhibitors of retroviral proteases acting on drug-resistant HIV-1.
Feline Infectious Peritonitis
Characterization of amino acid substitutions in feline coronavirus 3C-like protease from a cat with feline infectious peritonitis treated with a protease inhibitor.
Feline Infectious Peritonitis
Feline coronavirus drug inhibits the main protease of SARS-CoV-2 and blocks virus replication.
Feline Infectious Peritonitis
Protease inhibitor GC376 for COVID-19: Lessons learned from feline infectious peritonitis.
Femur Head Necrosis
[Possible complication of HIV therapy. Protease inhibitor-induced femur head necrosis]
Fetal Growth Retardation
Progesterone supplementation for HIV-positive pregnant women on protease inhibitor-based antiretroviral regimens (the ProSPAR study): a study protocol for a pilot randomized controlled trial.
Fetal Growth Retardation
Protease inhibitor therapy and fetal growth potential in HIV-positive women.
Fetal Hypoxia
[Protease inhibitors in the blood serum of parturients in cases of acute and chronic fetal anoxia]
Fetal Resorption
Anticardiolipin in Porphyromonas gingivalis Antisera Causes Fetal Loss in Mice.
Fibrocystic Breast Disease
Prostate specific antigen--a new constituent of breast cyst fluid.
Fibrocystic Breast Disease
Quantification of prostate-specific antigen immunoreactivity in human breast cyst fluids.
Fibrosarcoma
Anti-invasive activity of synthetic serine protease inhibitors and its combined effect with a matrix metalloproteinase inhibitor.
Fibrosarcoma
Autocrine induction of tumor protease production and invasion by a metallothionein-regulated TGF-beta 1 (Ser223, 225).
Fibrosarcoma
Differences in the Inhibitory Specificity Distinguish the Efficacy of Plant Protease Inhibitors on Mouse Fibrosarcoma.
Fibrosarcoma
HT-1080 fibrosarcoma cell matrix degradation and invasion are inhibited by the matrix-associated serine protease inhibitor TFPI-2/33 kDa MSPI.
Fibrosarcoma
Human skin fibroblast stromelysin: structure, glycosylation, substrate specificity, and differential expression in normal and tumorigenic cells.
Fibrosarcoma
Integral membrane protease fibroblast activation protein sensitizes fibrosarcoma to chemotherapy and alters cell death mechanisms.
Fibrosarcoma
Involvement of a serine protease in tumour-necrosis-factor-mediated cytotoxicity.
Fibrosarcoma
LIM-kinase is critical for the mesenchymal-to-amoeboid cell morphological transition in 3D matrices.
Fibrosarcoma
Plasminogen activator activity in clonogenic cell populations separated from a murine fibrosarcoma.
Fibrosarcoma
Proteolytic and metastatic activities of clones derived from a methylcholanthrene-induced murine fibrosarcoma.
Fibrosarcoma
[The effect of collagen and fibrin on the lysosomal protease activities of cultured fibrosarcoma (HT-1080)]
Filariasis
Antigenicity of a filarial protease from Setaria digitata in Wuchereria bancrofti infection.
Food Hypersensitivity
A role for early oral exposure to house dust mite allergens through breast milk in IgE-mediated food allergy susceptibility.
Food Hypersensitivity
Quail egg homogenate alleviates food allergy induced eosinophilic esophagitis like disease through modulating PAR-2 transduction pathway in peanut sensitized mice.
Foodborne Diseases
Effect of the cortex-lytic enzyme SleC from non-food-borne Clostridium perfringens on the germination properties of SleC-lacking spores of a food poisoning isolate.
Foodborne Diseases
Location and stoichiometry of the protease CspB and the cortex-lytic enzyme SleC in Clostridium perfringens spores.
Foodborne Diseases
The protease CspB is essential for initiation of cortex hydrolysis and dipicolinic acid (DPA) release during germination of spores of Clostridium perfringens type A food poisoning isolates.
Foot Rot
Pooling of interdigital swab samples for PCR detection of virulent Dichelobacter nodosus.
Foot Rot
Type IV fimbrial biogenesis is required for protease secretion and natural transformation in Dichelobacter nodosus.
Foot Ulcer
Mechanism of action of PROMOGRAN, a protease modulating matrix, for the treatment of diabetic foot ulcers.
Foot Ulcer
The Effectiveness of Negative Pressure Therapy in Diabetic Foot Ulcers with Elevated Protease Activity: A Case Series.
Foot-and-Mouth Disease
A region of the 5' noncoding region of foot-and-mouth disease virus RNA directs efficient internal initiation of protein synthesis within cells: involvement with the role of L protease in translational control.
Foot-and-Mouth Disease
Agroinfiltration contributes to VP1 recombinant protein degradation.
Foot-and-Mouth Disease
Biologically active protease of foot and mouth disease virus is expressed from cloned viral cDNA in Escherichia coli.
Foot-and-Mouth Disease
Characterization of an internal ribosomal entry segment in the 5' leader of murine leukemia virus env RNA.
Foot-and-Mouth Disease
Foot-and-Mouth Disease Virus 3C Protease Induces Fragmentation of the Golgi Compartment and Blocks Intra-Golgi Transport.
Foot-and-Mouth Disease
Foot-and-mouth disease virus assembly: processing of recombinant capsid precursor by exogenous protease induces self-assembly of pentamers in vitro in a myristoylation-dependent manner.
Foot-and-Mouth Disease
Internal translation initiation on the foot-and-mouth disease virus IRES is affected by ribosomal stalk conformation.
Foot-and-Mouth Disease
Intracellular expression and processing of foot-and-mouth disease virus capsid precursors using vaccinia virus vectors: influence of the L protease.
Foot-and-Mouth Disease
L protease from foot and mouth disease virus confers eIF2-independent translation for mRNAs bearing picornavirus IRES.
Foot-and-Mouth Disease
Molecular cloning and sequence determination of the genomic regions encoding protease and genome-linked protein of three picornaviruses.
Foot-and-Mouth Disease
Production of foot-and-mouth disease virus capsid proteins by the TEV protease.
Foot-and-Mouth Disease
Recognition of picornavirus internal ribosome entry sites within cells; influence of cellular and viral proteins.
Foot-and-Mouth Disease
Rhinovirus 2A proteinase mediated stimulation of rhinovirus RNA translation is additive to the stimulation effected by cellular RNA binding proteins.
Foot-and-Mouth Disease
Translation driven by picornavirus IRES is hampered from Sindbis virus replicons: rescue by poliovirus 2A protease.
Foot-and-Mouth Disease
[Morphological observation of bovine kidney (MDBK) cells effected by foot-and-mouth disease virus L(pro)]
Friedreich Ataxia
Oxidative stress and protease dysfunction in the yeast model of Friedreich ataxia.
Frontotemporal Dementia
Epitope mapping of antibodies against TDP-43 and detection of protease-resistant fragments of pathological TDP-43 in amyotrophic lateral sclerosis and frontotemporal lobar degeneration.
Frontotemporal Lobar Degeneration
Amyloid precursor protein expression is enhanced in human platelets from subjects with Alzheimer's disease and frontotemporal lobar degeneration: a real-time PCR study.
Frontotemporal Lobar Degeneration
Amyloid precursor protein expression is enhanced in human platelets from subjects with Alzheimer's disease and Frontotemporal lobar degeneration: A Real-time PCR study.
Frontotemporal Lobar Degeneration
Secretory Leukocyte Protease Inhibitor Protein Regulates the Penetrance of Frontotemporal Lobar Degeneration in Progranulin Mutation Carriers.
Frontotemporal Lobar Degeneration
The lysosomal protein cathepsin L is a progranulin protease.
Fucosidosis
Molecular heterogeneity in lysosomal storage diseases. Alpha-fucosidase and N-acetyl-beta-D-hexosaminidase deficiency variants.
Furunculosis
Defined deletion mutants demonstrate that the major secreted toxins are not essential for the virulence of Aeromonas salmonicida.
Furunculosis
Differential susceptibility of salmonid fishes to furunculosis correlates with differential serum enhancement of Aeromonas salmonicida extracellular protease activity.
Furunculosis
Identification of major common extracellular proteins secreted by Aeromonas salmonicida strains isolated from diseased fish.
Furunculosis
Inhibition of the Aeromonas salmonicida extracellular protease by alpha 2-macroglobulin in the serum of rainbow trout.
Furunculosis
Significance of Extracellular Protease for Growth of a Heterotrophic Bacterium, Aeromonas salmonicida.
Furunculosis
The role of alpha 2-macroglobulin in furunculosis: a comparison of rainbow trout and brook trout.
Gallstones
Evidence for oxidative stress in the gall bladder mucosa of gall stone patients.
Gallstones
Factors affecting the measurement of cholesterol nucleation in human gallbladder and duodenal bile.
Ganglioneuroma
Interleukin-1 beta converting enzyme (ICE) is preferentially expressed in neuroblastomas with favourable prognosis.
Gangliosidosis, GM1
Effects of thiol protease inhibitors on intracellular degradation of exogenous beta-galactosidase in cultured human skin fibroblasts.
Gas Gangrene
An efficient synthesis of benzodiazepinyl phosphonates as clostripain inhibitors via FeCl3 catalyzed four-component reaction.
Gastritis
Gastric mucosal inflammatory responses toHelicobacter pylori lipopolysaccharide: Suppression of caspase-3 and nitric oxide synthase-2 by omeprazole and sucralfate.
Gastritis
Helicobacter pylori-mediated gastritis induces local downregulation of secretory leukocyte protease inhibitor in the antrum.
Gastritis
Increased mucosal production of monomeric IgA1 but no IgA1 protease activity in Helicobacter pylori gastritis.
Gastritis
Induction of caspase-3 and nitric oxide synthase-2 during gastric mucosal inflammatory reaction to Helicobacter pylori lipopolysaccharide.
Gastritis
Number, fixation properties, dye-binding and protease expression of duodenal mast cells: comparisons between healthy subjects and patients with gastritis or Crohn's disease.
Gastritis
Relationship between histopathological status of the Helicobacter pylori infected patients and proteases of H. pylori in isolates carrying diverse virulence genotypes.
Gastritis
Secretory leukocyte protease inhibitor expression in various types of gastritis: a specific role of Helicobacter pylori infection.
Gastritis
[Effect of FUT-187, oral serine protease inhibitor, on inflammation in the gastric remnant]
Gastroenteritis
Aeromonas sobria serine protease (ASP): a subtilisin family endopeptidase with multiple virulence activities.
Gastroenteritis
Broad-Spectrum Antivirals against 3C or 3C-like Proteases of Picornaviruses, Noroviruses and Coronaviruses.
Gastroenteritis
Differences in production of several extracellular virulence factors in clinical and food Aeromonas spp. strains.
Gastroenteritis
GII.4 NOROVIRUS PROTEASE SHOWS pH-SENSITIVE PROTEOLYSIS WITH A UNIQUE ARG-HIS PAIRING IN THE CATALYTIC SITE.
Gastroenteritis
Identification of protease and ADP-ribose 1''-monophosphatase activities associated with transmissible gastroenteritis virus non-structural protein 3.
Gastroenteritis
Molecular quantification of virulence gene-containing Aeromonas in water samples collected from different drinking water treatment processes.
Gastroenteritis
Pathogenesis of gastroenteritis caused by Vibrio carchariae in cultured marine fish.
Gastroenteritis
Protease and virulence of the extracellular products produced by Vibrio carchariae after growth on various media.
Gastroenteritis
Variation of extracellular proteases produced by Vibrio vulnificus clinical isolates: genetic diversity of the metalloprotease gene (vvp), and serine protease secretion by vvp-negative strains.
Gastroesophageal Reflux
Gastroesophageal reflux disease does not lead to changes in the secretory leukocyte protease inhibitor expression in esophageal mucosa.
Gastrointestinal Diseases
A commensal Bifidobacterium longum strain improves gluten-related immunopathology in mice through expression of a serine protease inhibitor.
Gastrointestinal Diseases
Amprenavir: new preparation. Another HIV protease inhibitor: no proven advance.
Gastrointestinal Diseases
Mechanisms of disease: protease functions in intestinal mucosal pathobiology.
Gastrointestinal Diseases
Pathophysiological roles of proteases in gastrointestinal disease.
Gastrointestinal Diseases
Protease inhibitor plasma concentrations in HIV antiretroviral therapy.
Gastrointestinal Diseases
The current status of alpha-1-antityrpsin, a protease inhibitor, in gastrointestinal disease.
Gastrointestinal Neoplasms
Activation of the contact system in ascites from patients with gastrointestinal cancer.
Gaucher Disease
Pathologic gene expression in Gaucher disease: up-regulation of cysteine proteinases including osteoclastic cathepsin K.
Genetic Diseases, Inborn
Alpha -1 antitrypsin deficiency. The experience of Pulido Valente Hospital with augmentation therapya.
Genetic Diseases, Inborn
Analysis of the alpha-1-antitrypsin deficient alleles M3S, MZ, and ZZ by biochemical and molecular methods: a family study.
Genetic Diseases, Inborn
Environmental and genetic risk factors and gene-environment interactions in the pathogenesis of chronic obstructive lung disease.
Genetic Diseases, Inborn
Generalized dominant epidermolysis bullosa simplex: decreased activity of a gelatinolytic protease in cultured fibroblasts as a phenotypic marker.
Genetic Diseases, Inborn
Incidence, Prevalence, Etiology, and Prognosis of First-Time Chronic Pancreatitis in Young Patients: A Nationwide Cohort Study.
Genetic Diseases, Inborn
Matriptase drives early-onset intestinal failure in a mouse model of congenital tufting enteropathy.
Genetic Diseases, Inborn
Monoallelic expression of the protease inhibitor gene in humans, sheep, and cattle.
Genetic Diseases, Inborn
Neutrophil elastase activates near-silent epithelial Na+ channels and increases airway epithelial Na+ transport.
Genetic Diseases, Inborn
Proteasome protease mediated regulation of cytokine induction and inflammation.
Genetic Diseases, Inborn
Systemic administration of tripeptidyl peptidase I in a mouse model of late infantile neuronal ceroid lipofuscinosis: effect of glycan modification.
Genetic Diseases, Inborn
The Degradome database: expanding roles of mammalian proteases in life and disease.
Genetic Diseases, Inborn
Update on and future perspectives for the diagnosis of alpha-1 antitrypsin deficiency in Brazil.
Gestational Trophoblastic Disease
Expression pattern alterations of the serine protease HtrA1 in normal human placental tissues and in gestational trophoblastic diseases.
Giant Cell Tumor of Bone
Cathepsin K is the principal protease in giant cell tumor of bone.
Giant Cell Tumor of Bone
Protease expression in giant cell tumour of bone: a comparative study on feline and human samples.
Giant Cell Tumors
Protease expression in giant cell tumour of bone: a comparative study on feline and human samples.
Giant Cell Tumors
TGF-? induced PAR-1 expression promotes tumor progression and osteoclast differentiation in giant cell tumor of bone.
Gilbert Disease
Gilbert syndrome and the development of antiretroviral therapy-associated hyperbilirubinemia.
Gilbert Disease
Gilbert's syndrome and hyperbilirubinemia in protease inhibitor therapy--an extended haplotype of genetic variants increases risk in indinavir treatment.
Gingival Overgrowth
The possible potential therapeutic targets for drug induced gingival overgrowth.
Gingivitis
Adhesion of Porphyromonas gingivalis fimbriae to human gingival cell line Ca9-22.
Gingivitis
Cathepsins B, H and L activities in gingival crevicular fluid from chronic adult periodontitis patients and experimental gingivitis subjects.
Gingivitis
Identification of a cathepsin b-like protease in the crevicular fluid of gingivitis patients.
Gingivitis
Periodontal pathogens affect the level of protease inhibitors in gingival crevicular fluid.
Gingivitis
Predicted salivary human protease activity in experimental gingivitis revealed by endoProteo-FASP approach.
Gingivitis
Protease activity in gingival crevicular fluid from discrete periodontal sites in humans with periodontitis or gingivitis.
Gingivitis
Salivary Total Protease Activity Based on a Broad-Spectrum Fluorescence Resonance Energy Transfer Approach to Monitor Induction and Resolution of Gingival Inflammation.
Gingivitis
Trypsin-like, chymotrypsin-like and glycylprolyl dipeptidase activities in gingival crevicular fluid from human periodontal sites with gingivitis.
Gingivitis
[Innovative application of small molecules to influence -pathogenicity of dental plaque].
Gingivitis
[The correlationship between the protease activity and the epithelial cells in the saliva from the patients with gingivitis or marginal periodontitis (author's transl)]
Glaucoma, Angle-Closure
Alteration of the serine protease PRSS56 causes angle-closure glaucoma in mice and posterior microphthalmia in humans and mice.
Glaucoma, Angle-Closure
Evaluation of PRSS56 in Chinese subjects with high hyperopia or primary angle-closure glaucoma.
Glioblastoma
A Bifunctional Molecule with Lectin and Protease Inhibitor Activities Isolated from Crataeva tapia Bark Significantly Affects Cocultures of Mesenchymal Stem Cells and Glioblastoma Cells.
Glioblastoma
A Novel Compound Targeting Protease Receptor 1 Activators for the Treatment of Glioblastoma.
Glioblastoma
A novel role of tissue factor pathway inhibitor-2 in apoptosis of malignant human gliomas.
Glioblastoma
A phase I study of nelfinavir concurrent with temozolomide and radiotherapy in patients with glioblastoma multiforme.
Glioblastoma
Alpha-1-antichymotrypsin in human glioblastoma multiforme cells and its relation to GFAP immunostaining.
Glioblastoma
Calpain 2 is required for glioblastoma cell invasion: regulation of matrix metalloproteinase 2.
Glioblastoma
Calpain 2 is required for the invasion of glioblastoma cells in the zebrafish brain microenvironment.
Glioblastoma
Caspase-8: A Novel Target to Overcome Resistance to Chemotherapy in Glioblastoma.
Glioblastoma
Correction: Expression Analysis of All Protease Genes Reveals Cathepsin K to Be Overexpressed in Glioblastoma.
Glioblastoma
Down-regulation of cathepsin B expression impairs the invasive and tumorigenic potential of human glioblastoma cells.
Glioblastoma
Expression analysis of all protease genes reveals cathepsin K to be overexpressed in glioblastoma.
Glioblastoma
Fumonisin B1-induced apoptosis in neuroblastoma, glioblastoma and hypothalamic cell lines.
Glioblastoma
High-Affinity DARPin Allows Targeting of MeV to Glioblastoma Multiforme in Combination with Protease Targeting without Loss of Potency.
Glioblastoma
HIV protease inhibitors decrease VEGF/HIF-1alpha expression and angiogenesis in glioblastoma cells.
Glioblastoma
Immunohistochemical Evaluation of Hemostatic Changes in Glioblastoma Multiforme and Low-Grade Astrocytoma.
Glioblastoma
Increased expression of thymidylate synthetase (TS), ubiquitin specific protease 10 (USP10) and survivin is associated with poor survival in glioblastoma multiforme (GBM).
Glioblastoma
Matrix protease production, epithelial-to-mesenchymal transition marker expression and invasion of glioblastoma cells in response to osmotic or hydrostatic pressure.
Glioblastoma
Mutant cytoskeletal and ECM peptides sensitive to the ST14 protease are associated with a worse outcome for glioblastoma multiforme.
Glioblastoma
Overexpression and constitutive nuclear localization of cohesin protease Separase protein correlates with high incidence of relapse and reduced overall survival in glioblastoma multiforme.
Glioblastoma
Phosphatase and tensin homologue deficiency in glioblastoma confers resistance to radiation and temozolomide that is reversed by the protease inhibitor nelfinavir.
Glioblastoma
PIVL, a new serine protease inhibitor from Macrovipera lebetina transmediterranea venom, impairs motility of human glioblastoma cells.
Glioblastoma
Protease inhibitors interfere with the transforming growth factor-beta-dependent but not the transforming growth factor-beta-independent pathway of tumor cell-mediated immunosuppression.
Glioblastoma
Protease pretreatment increases the efficacy of adenovirus-mediated gene therapy for the treatment of an experimental glioblastoma model.
Glioblastoma
Purification of zymogen to plasminogen activator from human glioblastoma cells by affinity chromatography with monoclonal antibody.
Glioblastoma
Recombinant adeno-associated virus (rAAV) expressing TFPI-2 inhibits invasion, angiogenesis and tumor growth in a human glioblastoma cell line.
Glioblastoma
Restoration of tissue factor pathway inhibitor-2 in a human glioblastoma cell line triggers caspase-mediated pathway and apoptosis.
Glioblastoma
Role of plasminogen activator and of 92-KDa type IV collagenase in glioblastoma invasion using an in vitro matrigel model.
Glioblastoma
Targeting the cellular schizophrenia. Likely employment of the antipsychotic agent pimozide in treatment of refractory cancers and glioblastoma.
Glioblastoma
Ubiquitin-specific protease 15 promotes tumor cell invasion and proliferation in glioblastoma.
Glioblastoma
Ubiquitin-specific protease 28 is overexpressed in human glioblastomas and contributes to glioma tumorigenicity by regulating MYC expression.
Glioblastoma
Ubiquitin-specific protease 4 promotes glioblastoma multiforme via activating ERK pathway.
Glioblastoma
Ubiquitin-specific protease 8 links the PTEN-Akt-AIP4 pathway to the control of FLIPS stability and TRAIL sensitivity in glioblastoma multiforme.
Glioblastoma
Urokinase plasminogen activator, uPAR, MMP-2, and MMP-9 in the C6-glioblastoma rat model.
Glioblastoma
USP5 promotes tumorigenesis and progression of pancreatic cancer by stabilizing FoxM1 protein.
Glioma
?1,6 GlcNAc branches-modified protein tyrosine phosphatase Mu attenuates its tyrosine phosphatase activity and promotes glioma cell migration through PLC?-PKC pathways.
Glioma
A novel role of tissue factor pathway inhibitor-2 in apoptosis of malignant human gliomas.
Glioma
A protease storm cleaves a cell-cell adhesion molecule in cancer: multiple proteases converge to regulate PTPmu in glioma cells.
Glioma
Activating transcription factor 3 is overexpressed in human glioma and its knockdown in glioblastoma cells causes growth inhibition both in vitro and in vivo.
Glioma
Activation of matrix metalloproteinase-2 (MMP-2) by membrane type 1 matrix metalloproteinase through an artificial receptor for proMMP-2 generates active MMP-2.
Glioma
Anti-miRNA-23a Oligonucleotide Suppresses Glioma Cells Growth by Targeting Apoptotic Protease Activating Factor-1.
Glioma
Contribution of caspase-independent pathway to apoptosis in malignant glioma induced by carbon ion beams.
Glioma
Dibutyryl cAMP- or Interleukin-6-induced astrocytic differentiation enhances mannose binding lectin (MBL)-associated serine protease (MASP)-1/3 expression in C6 glioma cells.
Glioma
Differential activity of bcl-2 and ICE enzyme family protease inhibitors on Fas and puromycin-induced apoptosis of glioma cells.
Glioma
Differential gene expression in peritumoral brain zone of glioblastoma: role of SERPINA3 in promoting invasion, stemness and radioresistance of glioma cells and association with poor patient prognosis and recurrence.
Glioma
Downregulation of USP33 inhibits Slit/Robo signaling pathway and is associated with poor patient survival of glioma.
Glioma
Effects of the proteasome inhibitor ritonavir on glioma growth in vitro and in vivo.
Glioma
Expression of matrix metalloproteinases in human glioma cell lines in the presence of IL-10.
Glioma
High expression of cathepsin B and plasminogen activator inhibitor type-1 are strong predictors of survival in glioblastomas.
Glioma
Human glioma U-251 cells contain type 1 plasminogen activator inhibitor in a rapidly releasable form.
Glioma
Hypoxia-induced USP22-BMI1 axis promotes the stemness and malignancy of glioma stem cells via regulation of HIF-1?.
Glioma
Induction of glioma apoptosis by microglia-secreted molecules: The role of nitric oxide and cathepsin B.
Glioma
Inhibition of drug-induced DNA fragmentation, but not cell death, of glioma cells by non-caspase protease inhibitors.
Glioma
Inhibition of growth and induction of differentiation in a malignant human glioma cell line by normal leptomeningeal extracellular matrix proteins.
Glioma
Membrane-type 1 matrix metalloprotease (MT1-MMP) enables invasive migration of glioma cells in central nervous system white matter.
Glioma
Metalloproteinase disintegrins ADAM8 and ADAM19 are highly regulated in human primary brain tumors and their expression levels and activities are associated with invasiveness.
Glioma
Minimal and inducible regulation of tissue factor pathway inhibitor-2 in human gliomas.
Glioma
Modification of opioid receptor activity by acid phosphatase in neuroblastoma x glioma NG108-15 hybrid cells.
Glioma
Modulation of cystatin C expression impairs the invasive and tumorigenic potential of human glioblastoma cells.
Glioma
Overexpression of Protease Serine 8 Inhibits Glioma Cell Proliferation, Migration, and Invasion via Suppressing the Akt/mTOR Signaling Pathway.
Glioma
Physiological and chemical inducers of tissue factor pathway inhibitor-2 in human glioma cells.
Glioma
Plasminogen activator and inhibitor activity in human glioma cells and modulation by sodium butyrate.
Glioma
Post-Translational Regulation of Cathepsin B, but not of Other Cysteine Cathepsins, Contributes to Increased Glioblastoma Cell Invasiveness In Vitro.
Glioma
Prognostic significance of the immunohistochemical staining of cleaved caspase-3, an activated form of caspase-3, in gliomas.
Glioma
Protease inhibitors generate cytotoxic fragments from Alzheimer amyloid protein precursor in cDNA-transfected glioma cells.
Glioma
Protease Nexin-1 affects the migration and invasion of C6 glioma cells through the regulation of urokinase Plasminogen Activator and Matrix Metalloproteinase-9/2.
Glioma
Relevance of IGFBP2 proteolysis in glioma and contribution of the extracellular protease ADAMTS1.
Glioma
RNAi-mediated downregulation of urokinase plasminogen activator and its receptor in human meningioma cells inhibits tumor invasion and growth.
Glioma
Role of plasminogen activator and of 92-KDa type IV collagenase in glioblastoma invasion using an in vitro matrigel model.
Glioma
Secretion of protease nexin-1 by C6 glioma cells is under the control of a heterotrimeric G protein, Go1.
Glioma
Serine protease inhibitor (SERPIN) B1 suppresses cell migration and invasion in glioma cells.
Glioma
Spontaneous regression of experimental gliomas--an immunohistochemical and MRI study of the C6 glioma spheroid implantation model.
Glioma
The glioma cell-derived neurite promoting activity protein is functionally and immunologically related to human protease nexin-I.
Glioma
Ubiquitin-specific protease 22 acts as an oncoprotein to maintain glioma malignancy through deubiquitinating B cell-specific Moloney murine leukemia virus integration site 1 for stabilization.
Glioma
Ubiquitin-specific protease 22 promotes the proliferation, migration and invasion of glioma cells.
Glioma
Ubiquitin-specific protease 22: a novel molecular biomarker in glioma prognosis and therapeutics.
Glioma
Ubiquitin-specific protease 28 is overexpressed in human glioblastomas and contributes to glioma tumorigenicity by regulating MYC expression.
Glioma
USP18 deubiquitinates and stabilizes Twist1 to promote epithelial-mesenchymal transition in glioblastoma cells.
Glomerulonephritis
Amelioration of immune complex-mediated glomerulonephritis by synthetic protease inhibitors.
Glomerulonephritis
Deposition of alpha 1-antitrypsin and loss of glycoconjugate carrying Ulex europaeus agglutinin-I binding sites in the glomerular sclerotic process. Phenomena common to chronic pyelonephritis and chronic diffuse proliferative glomerulonephritis.
Glomerulonephritis
Distinct differences in autoantigen specificity of anti-neutrophil cytoplasm antibodies in systemic vasculitides and other inflammatory diseases.
Glomerulonephritis
Immunohistochemical detection of immunoglobulins and complements in formaldehyde-fixed and paraffin-embedded renal biopsy tissues; an adjunct for diagnosis of glomerulonephritis.
Glomerulonephritis
Induction of plasminogen activator inhibitor type 1 in murine lupus-like glomerulonephritis.
Glomerulonephritis
PR3 and Elastase Alter PAR1 Signaling and Trigger vWF Release via a Calcium-Independent Mechanism from Glomerular Endothelial Cells.
Glomerulonephritis
Predominance of IgG1 and IgG4 subclasses of anti-neutrophil cytoplasmic autoantibodies (ANCA) in patients with Wegener's granulomatosis and clinically related disorders.
Glomerulonephritis
Streptococcal pyrogenic exotoxin B antibodies in a mouse model of glomerulonephritis.
Glomerulonephritis
Urine proteome scans uncover total urinary protease, prostaglandin D synthase, serum amyloid P, and superoxide dismutase as potential markers of lupus nephritis.
Glomerulonephritis
Usp2-69 overexpression slows down the progression of rat anti-Thy1.1 nephritis.
Glomerulonephritis
[Effect of protease inhibitor on primary glomerulonephritis and the mechanism of the effect]
Glomerulonephritis, IGA
Evaluation of the staining findings of immunofluorescence in unfixed or fixed renal biopsy specimens from patients with IgA nephropathy and membranous nephropathy.
Glomerulonephritis, IGA
Increased mRNA expression encoding for medullasin in peripheral blood mononuclear cells from patients with IgA nephropathy.
Glomerulonephritis, IGA
Urinary insulin-like growth factors (IGF) and IGF-binding proteins in normal subjects, growth hormone deficiency, and renal disease.
Glomerulonephritis, IGA
[Association of single nucleotide polymorphism of megsin gene with IgA nephropathy]
Glomerulonephritis, Membranoproliferative
Immunohistochemical detection of immunoglobulins and complements in formaldehyde-fixed and paraffin-embedded renal biopsy tissues; an adjunct for diagnosis of glomerulonephritis.
Glomerulonephritis, Membranoproliferative
Membranoproliferative glomerulonephritis in childhood cirrhosis associated with alpha1-antitrypsin deficiency.
Glomerulonephritis, Membranoproliferative
Pathological aspects of membranoproliferative glomerulonephritis (MPGN) and haemolytic uraemic syndrome (HUS) / thrombocytic thrombopenic purpura (TTP).
Glomerulonephritis, Membranoproliferative
Protease nexin-1, tPA, and PAI-1 are upregulated in cryoglobulinemic membranoproliferative glomerulonephritis.
Glomerulonephritis, Membranous
Evaluation of the staining findings of immunofluorescence in unfixed or fixed renal biopsy specimens from patients with IgA nephropathy and membranous nephropathy.
Glomerulosclerosis, Focal Segmental
Apheresis in cryoglobulinemia complicating hepatitis C and in other renal diseases.
Glomerulosclerosis, Focal Segmental
Urinary insulin-like growth factors (IGF) and IGF-binding proteins in normal subjects, growth hormone deficiency, and renal disease.
Glucose Intolerance
AACTG recommendations for metabolic problems. Guide covers insulin resistance and diabetes.
Glucose Intolerance
Cardiovascular disease in patients infected with the human immunodeficiency virus.
Glucose Intolerance
Clinical lipoatrophy in HIV-1 patients on HAART is not associated with increased abdominal girth, hyperlipidaemia or glucose intolerance.
Glucose Intolerance
Effect of metformin and rosiglitazone on lipid metabolism in HIV infected patients receiving protease inhibitor containing HAART.
Glucose Intolerance
Effect of protease inhibitor therapy on glucose intolerance in pregnancy.
Glucose Intolerance
Fasting hyperinsulinemia and increased waist-to-hip ratios in non-wasting individuals with AIDS.
Glucose Intolerance
Impaired glucose tolerance in HIV-positive patients receiving and those not receiving protease inhibitors.
Glucose Intolerance
Impaired glucose tolerance, beta cell function and lipid metabolism in HIV patients under treatment with protease inhibitors.
Glucose Intolerance
Insulin resistance complicating pregnancy in a human immunodeficiency virus-infected patient treated with protease inhibitors and corticosteroids.
Glucose Intolerance
Metabolic response to a C-glucose load in human immunodeficiency virus patients before and after antiprotease therapy.
Glucose Intolerance
Protease inhibitor-based antiretroviral therapy and glucose tolerance in pregnancy: AIDS Clinical Trials Group A5084.
Glucose Intolerance
Protease inhibitors and decreased birth weight in HIV-infected pregnant women with impaired glucose tolerance.
Glucose Intolerance
The association between HIV, antiretroviral therapy, and gestational diabetes mellitus.
Glucose Intolerance
The HIV-1 protease inhibitor indinavir impairs insulin signalling in HepG2 hepatoma cells.
Glucose Intolerance
Therapeutic dose of HIV-1 protease inhibitor saquinavir does not permanently influence early insulin signaling.
glucose-6-phosphate dehydrogenase (nadp+) deficiency
Use of fosamprenavir, a sulfa-containing protease inhibitor, in HIV-infected patients with glucose-6-phosphate dehydrogenase deficiency.
Glucosephosphate Dehydrogenase Deficiency
Use of fosamprenavir, a sulfa-containing protease inhibitor, in HIV-infected patients with glucose-6-phosphate dehydrogenase deficiency.
Glycosuria
Impact of protease inhibitors on the evolution of urinary markers: Subanalyses from an observational cross-sectional study.
Gnathostomiasis
Transcriptome and excretory-secretory proteome of infective-stage larvae of the nematode Gnathostoma spinigerum reveal potential immunodiagnostic targets for development.
Gonorrhea
Degradation of immunoglobulins A2, A2, and G by suspected principal periodontal pathogens.
Gonorrhea
Studies on gonococcus infection. XVII. IgA1-cleaving protease in vaginal washings from women with gonorrhea.
Gonorrhea
[Protease activity of gonococci in patients with various clinical forms of gonorrhea]
Graft vs Host Disease
Host-Derived Serine Protease Inhibitor 6 Provides Granzyme B-Independent Protection of Intestinal Epithelial Cells in Murine Graft-versus-Host Disease.
Graft vs Host Disease
Potential usefulness of protease inhibitor and chloroquine in the treatment of transfusion-associated graft-versus-host disease.
Graft vs Host Disease
Serine protease detection in mixed lymphocyte cultures: a histochemical method for possible prediction of graft-versus-host disease.
Graft vs Host Disease
Treatment of post-transfusion graft-versus-host disease with nafmostat mesilate, a serine protease inhibitor.
Gram-Negative Bacterial Infections
Prc Contributes to Escherichia coli Evasion of Classical Complement-Mediated Serum Killing.
Gram-Positive Bacterial Infections
Cloning and the expression pattern of Spätzle gene during embryonic development and bacterial challenge in Artemia sinica.
Granuloma
Adjunct antibody administration with standard treatment reduces relapse rates in a murine tuberculosis model of necrotic granulomas.
Granuloma
Cathepsin-k as a diagnostic marker in the identification of micro-granulomas in Crohn's disease.
Granuloma
Collagenase, elastase, and nonspecific protease production by vigorous or immunomodulated liver granulomas and granuloma macrophages/eosinophils of S mansoni-infected mice.
Granuloma
Detection of alpha 2-macroglobulin, alpha 1-protease inhibitor, and neutral protease-antiprotease complexes within liver granulomas of Schistosoma mansoni-infected mice.
Granuloma
Distribution of polyethylene wear particles and bone fragments in periprosthetic tissue around total hip joint replacements.
Granuloma
HIV-associated lipodystrophy: a review of underlying mechanisms and therapeutic options.
Granuloma
PAR-1 signaling on macrophages is required for effective in vivo delayed-type hypersensitivity responses.
Granuloma
Paronychia with pyogenic granuloma in a child treated with indinavir: the retinoid-mediated side effect theory revisited.
Granuloma
Serine protease activity contributes to control of Mycobacterium tuberculosis in hypoxic lung granulomas in mice.
Granuloma
The production of plasminogen activator by afferent but not efferent lymph cells emigrating from chronic granulomatous lesions in sheep.
Granulomatosis with Polyangiitis
A linkage disequilibrium between genes at the serine protease inhibitor gene cluster on chromosome 14q32.1 is associated with Wegener's granulomatosis.
Granulomatosis with Polyangiitis
A Monoclonal Antibody (MCPR3-7) Interfering with the Activity of Proteinase 3 by an Allosteric Mechanism.
Granulomatosis with Polyangiitis
Antibodies to selected minor target antigens in patients with anti-neutrophil cytoplasmic antibodies (ANCA).
Granulomatosis with Polyangiitis
Antineutrophil cytoplasmic antibodies (ANCA) and systemic vasculitis: update of assays, immunopathogenesis, controversies, and report of a novel de novo ANCA-associated vasculitis after kidney transplantation.
Granulomatosis with Polyangiitis
Characterization of a recombinant proteinase 3, the autoantigen in Wegener's granulomatosis and its reactivity with anti-neutrophil cytoplasmic autoantibodies.
Granulomatosis with Polyangiitis
Characterization of monoclonal antibodies to proteinase-3 and application in the study of epitopes for classical anti-neutrophil cytoplasm antibodies.
Granulomatosis with Polyangiitis
Characterization of the processing and granular targeting of human proteinase 3 after transfection to the rat RBL or the murine 32D leukemic cell lines.
Granulomatosis with Polyangiitis
Cloning of cDNA for proteinase 3: a serine protease, antibiotic, and autoantigen from human neutrophils.
Granulomatosis with Polyangiitis
Distinct differences in autoantigen specificity of anti-neutrophil cytoplasm antibodies in systemic vasculitides and other inflammatory diseases.
Granulomatosis with Polyangiitis
Generation of anti-proteinase 3 monoclonal antibodies and development of immunological methods to detect endogenous proteinase 3.
Granulomatosis with Polyangiitis
Membrane-Associated Proteinase 3 on Granulocytes and Acute Myeloid Leukemia Inhibits T Cell Proliferation.
Granulomatosis with Polyangiitis
Predominance of IgG1 and IgG4 subclasses of anti-neutrophil cytoplasmic autoantibodies (ANCA) in patients with Wegener's granulomatosis and clinically related disorders.
Granulomatosis with Polyangiitis
The role of proteinase 3 (PR3) and the protease-activated receptor-2 (PAR-2) pathway in dendritic cell (DC) maturation of human-DC-like monocytes and murine DC.
Granulomatosis with Polyangiitis
Wegener's granulomatosis: antiproteinase 3 antibodies induce monocyte cytokine and prostanoid release-role of autocrine cell activation.
Gynecomastia
Another emerging event occurring during HIV infection treated with whatsoever antiretroviral therapy: frequency and role of gynecomastia.
Gynecomastia
Breast enlargement in 13 men who were seropositive for human immunodeficiency virus.
Gynecomastia
Gynecomastia, lipodystrophy syndrome, and dyslipidemia occurring or worsening during antiretroviral regimens other than protease inhibitor-based ones.
Head and Neck Neoplasms
Effect of reoxygenation on the hypoxia-induced up-regulation of serine protease inhibitor PAI-1 in head and neck cancer cells.
Head and Neck Neoplasms
Human papillomavirus infection in head and neck cancer: The role of the secretory leukocyte protease inhibitor.
Head and Neck Neoplasms
Salivary secretory leukocyte protease inhibitor (SLPI) and head and neck cancer: The Cancer Prevention Study II Nutrition Cohort.
Head and Neck Neoplasms
TMPRSS2, a SARS-CoV-2 internalization protease is downregulated in head and neck cancer patients.
Head and Neck Neoplasms
[Mechanisms of invasiveness of cancers of the head and neck region]
Hearing Loss
A novel de novo CAPN5 mutation in a patient with inflammatory vitreoretinopathy, hearing loss, and developmental delay.
Hearing Loss
A novel mutation of TMPRSS3 related to milder auditory phenotype in Korean postlingual deafness: a possible future implication for a personalized auditory rehabilitation.
Hearing Loss
Absence of SERPINB6A causes sensorineural hearing loss with multiple histopathologies in the mouse inner ear.
Hearing Loss
Genetic analysis of TMPRSS3 gene in the Korean population with autosomal recessive nonsyndromic hearing loss.
Hearing Loss
Insertion of beta-satellite repeats identifies a transmembrane protease causing both congenital and childhood onset autosomal recessive deafness.
Hearing Loss
Molecular analysis of the TMPRSS3 gene in Moroccan families with non-syndromic hearing loss.
Hearing Loss
Novel Mutations in the TMPRSS3 Gene may Contribute to Taiwanese Patients with Nonsyndromic Hearing Loss.
Hearing Loss, Sensorineural
TMPRSS3 regulates cell viability and apoptosis processes of HEI-OC1 cells via regulation of the circ-Slc4a2, miR-182 and Akt cascade.
Heart Arrest
Activation of CPP-32 protease in hippocampal neurons following ischemia and epilepsy.
Heart Defects, Congenital
Decreased plasma ADAMTS-13 activity as a predictor of postoperative bleeding in cyanotic congenital heart disease.
Heart Diseases
A randomized, double-blind study of gemfibrozil for the treatment of protease inhibitor-associated hypertriglyceridaemia.
Heart Diseases
Diagnosis and Management of Acquired von Willebrand Disease in Heart Disease: A Review of the Literature.
Heart Diseases
Effects of spermine-conjugated Bowman-Birk inhibitor (spermine-BBI) on carcinogenesis and cholesterol biosynthesis in mice.
Heart Diseases
Myocardial matrix remodeling and the matrix metalloproteinases: influence on cardiac form and function.
Heart Diseases
Orphan nuclear receptor HNF-4 binds to the human coagulation factor VII promoter.
Heart Diseases
Prelamin A mediates myocardial inflammation in dilated and HIV-associated cardiomyopathies.
Heart Diseases
Protease inhibitors: emerging research explores possible link with heart disease. Experts say PI therapy remains essential for most.
Heart Diseases
Treatment with a fixed dose combination antiretroviral therapy drug containing tenofovir, emtricitabine and efavirenz is associated with cardioprotection in high calorie diet-induced obese rats.
Heart Failure
Activation and modulation of 72kDa matrix metalloproteinase-2 by peroxynitrite and glutathione.
Heart Failure
Angiotensin I and II. Some early observations made at the Cleveland Clinic Foundation and recent discoveries relative to angiotensin II formation in human heart.
Heart Failure
Ankyrin-B Protein in Heart Failure: IDENTIFICATION OF A NEW COMPONENT OF METAZOAN CARDIOPROTECTION.
Heart Failure
Astragaloside IV alleviates heart failure by regulating SUMO-specific protease 1.
Heart Failure
Cardiac-Specific Overexpression of Catalytically Inactive Corin Reduces Edema, Contractile Dysfunction, and Death in Mice with Dilated Cardiomyopathy.
Heart Failure
Cathepsin A inhibition attenuates myocardial infarction-induced heart failure on the functional and proteomic levels.
Heart Failure
Congestive heart failure model in rabbits: effects of digoxin and a drug containing toad venom.
Heart Failure
Cystatin C in heart failure is nothing more than a bystander of glomerular filtration.
Heart Failure
E-C coupling structural protein junctophilin-2 encodes a stress-adaptive transcription regulator.
Heart Failure
Effects of "kyushin", a drug containing toad venom, on experimental congestive heart failure in rabbits.
Heart Failure
Imaging of infarct healing predicts left ventricular remodeling and evolution of heart failure: focus on protease activity.
Heart Failure
Molecular Implications of Natriuretic Peptides in the Protection from Hypertension and Target Organ Damage Development.
Heart Failure
Myocardial matrix remodeling and the matrix metalloproteinases: influence on cardiac form and function.
Heart Failure
Myocardial Upregulation of Cathepsin D by Ischemic Heart Disease Promotes Autophagic Flux and Protects Against Cardiac Remodeling and Heart Failure.
Heart Failure
Nafamostat mesilate modulates the release of platelet-activating factor during left ventricular assistance with hemofiltration in canine heart failure.
Heart Failure
Neprilysin Inhibition Increases Glucagon Levels in Humans and Mice With Potential Effects on Amino Acid Metabolism.
Heart Failure
Oxidative post-translational modifications develop LONP1 dysfunction in pressure overload heart failure.
Heart Failure
Oxidative Stress as A Mechanism for Functional Alterations in Cardiac Hypertrophy and Heart Failure.
Heart Failure
Relation of serum levels of mast cell tryptase of left ventricular systolic function, left ventricular volume or congestive heart failure.
Heart Failure
Vasopeptidase inhibitor reduces inhospital costs for patients with congestive heart failure: results from the IMPRESS trial. Inhibition of Metallo Protease by BMS-186716 in a Randomized Exercise and Symptoms Study in Subjects With Heart Failure.
Heart Septal Defects, Ventricular
Meltrin beta expressed in cardiac neural crest cells is required for ventricular septum formation of the heart.
Heart Valve Diseases
The behavior of antithrombin III, alpha 2 macroglobulin, and alpha 1 antitrypsin during cardiopulmonary bypass.
HELLP Syndrome
May human epididymis 4 protein play a role in the etiopathogenesis of hemolysis, elevated liver enzymes and low platelets (HELLP) syndrome?
HELLP Syndrome
Placental expression of proteases and their inhibitors in patients with HELLP syndrome.
Helminthiasis
Transcriptome and excretory-secretory proteome of infective-stage larvae of the nematode Gnathostoma spinigerum reveal potential immunodiagnostic targets for development.
Hemangioma, Cavernous, Central Nervous System
c-Myc regulates the coordinated transcription of brain disease-related PDCD10-SERPINI1 bidirectional gene pair.
Hemangiosarcoma
Effects of indinavir in a preliminary phase I study on dogs with stage III slenic hemangiosarcoma.
Hemarthrosis
Rare and Unusual Bleeding Manifestations in Congenital Bleeding Disorders: An Annotated Review.
Hematologic Diseases
[Accessory use of protease-inhibiting agents for disease remission in a patient with autoimmune hemolytic anemia associated with B-CLL]
Hematologic Neoplasms
Comparison of Danaparoid Sodium and Synthetic Protease Inhibitors for the Treatment of Disseminated Intravascular Coagulation Associated with Hematological Malignancies: A Retrospective Analysis.
Hematologic Neoplasms
Comparison of gabexate mesilate and nafamostat mesilate for disseminated intravascular coagulation associated with hematological malignancies.
Hematologic Neoplasms
Extracellular Vesicles in Hematological Malignancies: From Biomarkers to Therapeutic Tools.
Hematologic Neoplasms
Improved nonclinical safety profile of a novel, highly selective inhibitor of the immunoproteasome subunit LMP7 (M3258).
Hematologic Neoplasms
Mitochondrial ClpP serine protease-biological function and emerging target for cancer therapy.
Hematologic Neoplasms
Mutation analysis of the FAS and TNFR apoptotic cascade genes in hematological malignancies.
Hematologic Neoplasms
Plasminogen activator inhibitor-2 in patients with monocytic leukemia.
Hematuria
Enzymolysis of glomerular immune deposits in vivo with dextranase/protease ameliorates proteinuria, hematuria, and mesangial proliferation in murine experimental IgA nephropathy.
Hematuria
Impact of protease inhibitors on the evolution of urinary markers: Subanalyses from an observational cross-sectional study.
Hemochromatosis
Associations of genetically determined iron status across the phenome: A mendelian randomization study.
Hemochromatosis
Genetic factors influencing ferritin levels in 14,126 blood donors: results from the Danish Blood Donor Study.
Hemochromatosis
Genetic Variants Influencing Biomarkers of Nutrition Are Not Associated with Cognitive Capability in Middle-Aged and Older Adults.
Hemochromatosis
Genome-wide association study of iron traits and relation to diabetes in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL): potential genomic intersection of iron and glucose regulation?
Hemoglobinuria
Protease inhibitors and haptoglobin for treatment of renal failure in paroxysmal nocturnal hemoglobinuria.
Hemoglobinuria
Small-molecule factor D inhibitors targeting the alternative complement pathway.
Hemoglobinuria, Paroxysmal
Protease inhibitors and haptoglobin for treatment of renal failure in paroxysmal nocturnal hemoglobinuria.
Hemoglobinuria, Paroxysmal
Small-molecule factor D inhibitors targeting the alternative complement pathway.
Hemolytic-Uremic Syndrome
Assay of von Willebrand factor (vWF)-cleaving protease based on decreased collagen binding affinity of degraded vWF: a tool for the diagnosis of thrombotic thrombocytopenic purpura (TTP)
Hemolytic-Uremic Syndrome
EspP, an Extracellular Serine Protease from Enterohemorrhagic E. coli, Reduces Coagulation Factor Activities, Reduces Clot Strength, and Promotes Clot Lysis.
Hemolytic-Uremic Syndrome
Specific von Willebrand factor-cleaving protease in thrombotic microangiopathies: a study of 111 cases.
Hemolytic-Uremic Syndrome
von Willebrand factor-cleaving protease in thrombotic thrombocytopenic purpura and the hemolytic-uremic syndrome.
Hemophilia A
A case of successful hepatitis C virus eradication by 24 weeks of telaprevir-based triple therapy for a hemophilia patient with hepatitis C virus/human immunodeficiency virus co-infection who previously failed pegylated interferon-? and ribavirin therapy.
Hemophilia A
Deconvoluting the Composition of Low-Frequency Hepatitis C Viral Quasispecies: Comparison of Genotypes and NS3 Resistance-Associated Variants between HCV/HIV Coinfected Hemophiliacs and HCV Monoinfected Patients in Japan.
Hemophilia A
Design, synthesis and biological activity of novel peptidyl benzyl ketone FVIIa inhibitors.
Hemophilia A
Engineering a protein Z-dependent protease inhibitor (ZPI) mutant as a novel antagonist of ZPI anticoagulant function for hemophilia treatment.
Hemophilia A
Increased bleeding in HIV-positive haemophiliacs treated with antiretroviral protease inhibitors.
Hemophilia A
Low molecular weight activated protein C inhibitors as a potential treatment for hemophilic disorders.
Hemophilia A
Monitoring but no drug-regimen changes advised for hemophilia patients taking protease inhibitors.
Hemophilia A
Phage-assisted continuous evolution of proteases with altered substrate specificity.
Hemophilia A
Plasma concentration of protein Z and protein Z-dependent protease inhibitor in patients with haemophilia A.
Hemophilia A
Rare and Unusual Bleeding Manifestations in Congenital Bleeding Disorders: An Annotated Review.
Hemophilia A
Targeting Protease Nexin-1, a natural anticoagulant serpin, to control bleeding and improve hemostasis in hemophilia.
Hemophilia B
A codon 338 nonsense mutation in the factor IX gene in unrelated hemophilia B patients: factor IX338 New York.
Hemophilia B
A moderate form of hemophilia B is caused by a novel mutation in the protease domain of factor IXVancouver.
Hemophilia B
Extracellular proteases and their inhibitors in genetic diseases of the central nervous system.
Hemophilia B
Hemophilia B caused by five different nondeletion mutations in the protease domain of factor IX.
Hemophilia B
Identification of zebrafish ortholog for human coagulation factor IX and its age-dependent expression.
Hemophilia B
Region of factor IXa protease domain that interacts with factor VIIIa: analysis of select hemophilia B mutants.
Hemorrhagic Disorders
[The protease inhibitor treatment of the disseminated intravascular coagulation syndrome in patients with liver cirrhosis]
Hemorrhagic Fever, Crimean
Crimean-Congo Hemorrhagic Fever Virus Suppresses Innate Immune Responses via a Ubiquitin and ISG15 Specific Protease.
Hemorrhagic Fever, Crimean
Crimean-Congo hemorrhagic fever virus-encoded ovarian tumor (OTU) protease activity is dispensable for virus RNA polymerase function.
Hemorrhagic Fever, Crimean
Inherent dynamics within the Crimean-Congo Hemorrhagic fever virus protease are localized to the same region as substrate interactions.
Hemorrhagic Fever, Crimean
Probing the impact of nairovirus genomic diversity on viral ovarian tumor domain protease (vOTU) structure and deubiquitinase activity.
Hemorrhagic Fever, Crimean
Structural analysis of a viral ovarian tumor domain protease from the crimean-congo hemorrhagic Fever virus in complex with covalently bonded ubiquitin.
Hemorrhagic Fever, Ebola
A Synthetic Serine Protease Inhibitor, Nafamostat Mesilate, Is a Drug Potentially Applicable to the Treatment of Ebola Virus Disease.
Hemorrhagic Stroke
Efficacy and Mechanism of Butylphthalide Combined with Atorvastatin Calcium Tablets in the Diagnosis of Cerebral Infarction Using Iodol/Fe?O? Nanometric Contrast Agent.
Hepatic Encephalopathy
Role of serine protease inhibitor, ulinastatin, in rat model of hepatic encephalopathy: aquaporin 4 molecular targeting and therapeutic implication.
Hepatitis
Acute clinical hepatitis in an HIV-seropositive hepatitis B carrier receiving protease inhibitor therapy.
Hepatitis
Construction of hepatitis C-SIN virus recombinants with replicative dependency on hepatitis C virus serine protease activity.
Hepatitis
Coronaviruses resistant to a 3C-like protease inhibitor are attenuated for replication and pathogenesis, revealing a low genetic barrier but high fitness cost of resistance.
Hepatitis
Development of boceprevir: a first-in-class direct antiviral treatment for chronic hepatitis C infection.
Hepatitis
Development of hepatotoxicity in HIV patients switching at least one protease inhibitor.
Hepatitis
Drug-Drug Interactions With Antiviral Agents in People Who Inject Drugs Requiring Substitution Therapy.
Hepatitis
Evaluation of the susceptibility of the 3C proteases of hepatitis A virus and poliovirus to degradation by the ubiquitin-mediated proteolytic system.
Hepatitis
Evidence for the presence of an inactive precursor of human hepatocyte growth factor in plasma and sera of patients with liver diseases.
Hepatitis
Gilbert's syndrome and hyperbilirubinemia in protease inhibitor therapy--an extended haplotype of genetic variants increases risk in indinavir treatment.
Hepatitis
Hepatitis G virus encodes protease activities which can effect processing of the virus putative nonstructural proteins.
Hepatitis
Hepatitis: Proof of concept for antiviral activity of protease inhibitor TMC435 monotherapy against multiple HCV genotypes.
Hepatitis
Hepatotoxicity associated with antiretroviral therapy in adults infected with human immunodeficiency virus and the role of hepatitis C or B virus infection.
Hepatitis
Hepatotoxicity associated with nevirapine or efavirenz-containing antiretroviral therapy: role of hepatitis C and B infections.
Hepatitis
Hepatotoxicity associated with protease inhibitor-based antiretroviral regimens with or without concurrent ritonavir.
Hepatitis
Hepatotoxicity development during antiretroviral therapy containing protease inhibitors in patients with HIV: the role of hepatitis B and C virus infection.
Hepatitis
HIV Drug Resistance Testing in a Resource Limited Setting with high Viral Diversity: The first Twenty Eight Months Experience.
Hepatitis
In vivo evidence for protease-catalysed mechanism providing bioactive tumor necrosis factor alpha.
Hepatitis
Involvement of a serine protease, but not of neutrophil elastase, in tumor necrosis factor-induced lethal hepatitis and induction of platelet-activating factor.
Hepatitis
Pentoxifylline inhibits anti-Fas antibody-induced hepatitis by affecting downstream of CPP32-like activity in mice.
Hepatitis
Plasma levels of the von Willebrand factor-cleaving protease in physiological and pathological conditions in children.
Hepatitis
Potent peptide inhibitors of human hepatitis C virus NS3 protease are obtained by optimizing the cleavage products.
Hepatitis
Probable corticosteroid-induced reactivation of latent hepatitis B virus infection in an HIV-positive patient involving immune escape.
Hepatitis
Putative papain-related thiol proteases of positive-strand RNA viruses. Identification of rubi- and aphthovirus proteases and delineation of a novel conserved domain associated with proteases of rubi-, alpha- and coronaviruses.
Hepatitis
Role of protease in mouse hepatitis virus-induced cell fusion. Studies with a cold-sensitive mutant isolated from a persistent infection.
Hepatitis
Serum activity of prolyl endopeptidase, but not of dipeptidyl peptidase IV, is decreased by immunotherapy with IFN-alpha in high-risk melanoma patients.
Hepatitis
Severe hepatitis in a HIV-positive subject under treatment with protease inhibitor.
Hepatitis
Solid phase synthesis of peptide aldehyde protease inhibitors. Probing the proteolytic sites of hepatitis C virus polyprotein.
Hepatitis
Telaprevir- and Boceprevir-Based Triple Therapy for Hepatitis C in Liver Transplant Recipients With Advanced Recurrent Disease: A Multicenter Study.
Hepatitis
The addition of a protease inhibitor increases the risk of infections in patients with hepatitis C-related cirrhosis.
Hepatitis
The pathobiology of viral hepatitis and immunologic activation of the coagulation protease network.
Hepatitis
The protective effect of cyclosporine A on anti-Fas antibody-induced hepatitis in mice.
Hepatitis
The protective effect of glycyrrhizin on anti-Fas antibody-induced hepatitis in mice.
Hepatitis
Tolerability of postexposure antiretroviral prophylaxis for occupational exposures to HIV.
Hepatitis
Ubiquitously specific protease 4 inhibitor-Vialinin A attenuates inflammation and fibrosis in S100-induced hepatitis mice through Rheb/mTOR signalling.
Hepatitis
[Alpha 1-antitrypsin deficiency: a review with special reference to the significance of heterozygous deficiency]
Hepatitis
[Association of immune system gene polymorphisms with quantitative features which are pathogenetically important in chronic viral hepatitis]
Hepatitis
[Hfgl2/fibroleukin expression in liver and peripheral blood mononuclear cells (PBMC) and its correlation with disease severity]
Hepatitis
[Therapy spectrum in hepatitis C extended. Newer NS3/4A protease inhibitor in chronic hepatitis C-GT1/4 infection].
Hepatitis A
Disruption of TLR3 signaling due to cleavage of TRIF by the hepatitis A virus protease-polymerase processing intermediate, 3CD.
Hepatitis A
HCV genotype 1-6 NS3 residue 80 substitutions impact protease inhibitor activity and promote viral escape.
Hepatitis A
Protease digestion of hepatitis A virus: disparate effects on capsid proteins, antigenicity, and infectivity.
Hepatitis A
RNA interaction and cleavage of poly(C)-binding protein 2 by hepatitis A virus protease.
Hepatitis B
ACTG A5353: A pilot study of dolutegravir plus lamivudine for initial treatment of HIV-1-infected participants with HIV-1 RNA < 500,000 copies/mL.
Hepatitis B
Acute clinical hepatitis in an HIV-seropositive hepatitis B carrier receiving protease inhibitor therapy.
Hepatitis B
Elevated plasma concentrations of protease inhibitors and nonnucleoside reverse transcriptase inhibitors in patients coinfected with human immunodeficiency virus and hepatitis B or C: case series and literature review.
Hepatitis B
Factors associated with long-term CD4 cell recovery in HIV-infected patients on successful antiretroviral therapy.
Hepatitis B
Glecaprevir/pibrentasvir-associated acute liver injury in non-cirrhotic, chronic HCV infection without HBV co-infection.
Hepatitis B
Hepadnavirus envelope topology: insertion of a loop region in the membrane and role of S in L protein translocation.
Hepatitis B
Hepatitis B and Hepatitis C virus replication up-regulate serine protease inhibitor Kazal, resulting in cellular resistance to serine protease dependent apoptosis.
Hepatitis B
Hepatitis B or hepatitis C virus infection is a risk factor for severe hepatic cytolysis after initiation of a protease inhibitor-containing antiretroviral regimen in human immunodeficiency virus-infected patients. The APROCO Study Group.
Hepatitis B
Hepatitis B Virus X Protein-Induced Serine Protease Inhibitor Kazal Type 1 Is Associated with the Progression of HBV-Related Diseases.
Hepatitis B
Hepatotoxicity associated with antiretroviral therapy in adults infected with human immunodeficiency virus and the role of hepatitis C or B virus infection.
Hepatitis B
Hepatotoxicity development during antiretroviral therapy containing protease inhibitors in patients with HIV: the role of hepatitis B and C virus infection.
Hepatitis B
HIV Reverse Transcriptase and Protease Genes Variability Can Be a Biomarker Associated with HIV and Hepatitis B or C Coinfection.
Hepatitis B
Human hepatitis B virus X protein promotes cell proliferation and inhibits cell apoptosis through interacting with a serine protease Hepsin.
Hepatitis B
Identification and monitoring of protease activity in recombinant Saccharomyces cerevisiae.
Hepatitis B
Identification of a doubly spliced viral transcript joining the separated domains for putative protease and reverse transcriptase of hepatitis B virus.
Hepatitis B
In vitro activity and resistance profile of samatasvir, a novel NS5A replication inhibitor of hepatitis C virus.
Hepatitis B
Influence of ABCC2 and ABCC4 polymorphisms on tenofovir plasma concentrations in Thai HIV-infected patients.
Hepatitis B
Mucosal immunization of mice using CpG DNA and/or mutants of the heat-labile enterotoxin of Escherichia coli as adjuvants.
Hepatitis B
Prevalence and factors associated with HIV-1 multi-drug resistance over the past two decades in the Italian ARCA database.
Hepatitis B
Proteaselike sequence in hepatitis B virus core antigen is not required for e antigen generation and may not be part of an aspartic acid-type protease.
Hepatitis B
Sequential cleavage by metallopeptidases and proteasomes is involved in processing HIV-1 ENV epitope for endogenous MHC class I antigen presentation.
Hepatitis B
Three sites of the hepatitis B virus X protein cooperatively interact with cellular proteins.
Hepatitis B
Topology of the large envelope protein of duck hepatitis B virus suggests a mechanism for membrane translocation during particle morphogenesis.
Hepatitis B
[Comparisons of the characteristics and mechanisms of HBV replication in QSG-7701 and HepG2 cell lines]
Hepatitis B
[National Consensus Document by GESIDA/National Aids Plan on Antiretroviral Treatment in Adults Infected by the Human Immunodeficiency Virus (January 2011 Update).]
Hepatitis B, Chronic
Clinical outcomes in patients with chronic hepatitis C after direct-acting antiviral treatment: a prospective cohort study.
Hepatitis B, Chronic
Controlled-release interferon alpha 2b, a new member of the interferon family for the treatment of chronic hepatitis C.
Hepatitis B, Chronic
Hepatitis B and C virus co-infection and the risk for hepatotoxicity of highly active antiretroviral therapy in HIV-1 infection.
Hepatitis B, Chronic
Hepatotoxicity following nevirapine-containing regimens in HIV-1-infected individuals.
Hepatitis B, Chronic
Restoration of immunity to chronic hepatitis B infection in HIV-infected patient on protease inhibitor.
Hepatitis B, Chronic
Transcriptional response of USP18 predicts treatment outcomes of interferon-alpha in HBeAg-positive chronic hepatitis B patientsefere.
Hepatitis B, Chronic
[Darunavir/cobicistat monotherapy. Experience in a tertiary hospital].
Hepatitis C
A case of successful treatment with telaprevir-based triple therapy for hepatitis C infection after treatment failure with vaniprevir-based triple therapy.
Hepatitis C
A cellular replicon-based phenotyping assay to determine susceptibility of hepatitis C virus clinical isolates to NS3/4A protease inhibitors.
Hepatitis C
A central hydrophobic domain of the hepatitis C virus NS4A protein is necessary and sufficient for the activation of the NS3 protease.
Hepatitis C
A Chemically-Disrupted Proximity System for Controlling Dynamic Cellular Processes.
Hepatitis C
A comparative analysis of the substrate permissiveness of HCV and GBV-B NS3/4A proteases reveals genetic evidence for an interaction with NS4B protein during genome replication.
Hepatitis C
A comparative QM/MM study of the reaction mechanism of the Hepatitis C virus NS3/NS4A protease with the three main natural substrates NS5A/5B, NS4B/5A and NS4A/4B.
Hepatitis C
A complete mutational fitness map of the hepatitis C virus nonstructural 3 protease: relation to recognition by cytotoxic T lymphocytes.
Hepatitis C
A computational drug repurposing approach in identifying the cephalosporin antibiotic and anti-hepatitis C drug derivatives for COVID-19 treatment.
Hepatitis C
A continuous assay of hepatitis C virus protease based on resonance energy transfer depsipeptide substrates.
Hepatitis C
A continuous spectrophotometric assay for the hepatitis C virus serine protease.
Hepatitis C
A doublet-separated sensitivity-enhanced HSQC for the determination of scalar and dipolar one-bond J-couplings.
Hepatitis C
A dual fluorescent/MALDI chip platform for analyzing enzymatic activity and for protein profiling.
Hepatitis C
A Highly Convergent and Efficient Synthesis of a Macrocyclic Hepatitis C Virus Protease Inhibitor BI 201302.
Hepatitis C
A Lead-In with Silibinin Prior to Triple-Therapy Translates into Favorable Treatment Outcomes in Difficult-To-Treat HIV/Hepatitis C Coinfected Patients.
Hepatitis C
A method to simultaneously monitor hepatitis C virus NS3 helicase and protease activities.
Hepatitis C
A novel recombinant single-chain hepatitis C virus NS3-NS4A protein with improved helicase activity.
Hepatitis C
A particular hepatitis C virus protease NS3 gene pattern in a patient not responding to interferon-ribavirin therapy.
Hepatitis C
A point mutation abolishes the helicase but not the nucleoside triphosphatase activity of hepatitis C virus NS3 protein.
Hepatitis C
A probabilistic peptide machine for predicting hepatitis C virus protease cleavage sites.
Hepatitis C
A quantum mechanics/molecular mechanics study of the reaction mechanism of the hepatitis C virus NS3 protease with the NS5A/5B substrate.
Hepatitis C
A rare and severe cutaneous adverse effect of telaprevir: drug rash with eosinophilia and systemic symptoms.
Hepatitis C
A reduced grade of liver fibro-steatosis after raltegravir, maraviroc and fosamprenavir in an HIV/HCV co-infected patient with chronic hepatitis, cardiomyopathy, intolerance to nelfinavir and a marked increase of serum creatine phosphokinase levels probably related to integrase inhibitor use.
Hepatitis C
A rugged and accurate liquid chromatography-tandem mass spectrometry method for the determination of asunaprevir, an NS3 protease inhibitor, in plasma.
Hepatitis C
A scintillation proximity active site binding assay for the hepatitis C virus serine protease.
Hepatitis C
A small percentage of patients with hepatitis C receive triple therapy with boceprevir or telaprevir.
Hepatitis C
A Survey of Hepatitis C Treatment Clinical Practice Patterns Using the Newly Approved Protease Inhibitors.
Hepatitis C
A Synthesis of a Spirocyclic Macrocyclic Protease Inhibitor for the Treatment of Hepatitis C.
Hepatitis C
A system for the continuous directed evolution of proteases rapidly reveals drug-resistance mutations.
Hepatitis C
A time-resolved, internally quenched fluorescence assay to characterize inhibition of hepatitis C virus nonstructural protein 3-4A protease at low enzyme concentrations.
Hepatitis C
A transient cell-based phenotype assay for hepatitis C NS3/4A protease: application to potency determinations of a novel macrocyclic inhibitor against diverse protease sequences isolated from plasma infected with HCV.
Hepatitis C
A Twenty-Eight-Day Mechanistic Time Course Study in the Rhesus Monkey with Hepatitis C Virus Protease Inhibitor Biln 2061.
Hepatitis C
A1-2: Cost-Effectiveness of Interleukin 28B Genotype-Guided Protease Inhibitor Therapy in Treatment-Naive Patients with Hepatitis C Virus Genotype 2 or 3.
Hepatitis C
Abrogation of hepatitis C virus NS3 helicase enzymatic activity by recombinant human antibodies.
Hepatitis C
ABT-450, ritonavir, ombitasvir, and dasabuvir achieves 97% and 100% sustained virologic response with or without ribavirin in treatment-experienced patients with HCV genotype 1b infection.
Hepatitis C
ABT-450: A Novel Protease Inhibitor for the Treatment of Hepatitis C Virus Infection.
Hepatitis C
Activity-based proteome profiling of hepatoma cells during hepatitis C virus replication using protease substrate probes.
Hepatitis C
Acyl sulfonamides as potent protease inhibitors of the hepatitis C virus full-Length NS3 (protease-helicase/NTPase): a comparative study of different C-terminals.
Hepatitis C
Adapted J6/JFH1-based hepatitis C virus recombinants with genotype-specific NS4A show similar efficacy to lead protease inhibitors, interferon-alpha and a putative NS4A inhibitor.
Hepatitis C
Add-on effects of fluvastatin in simeprevir/pegylated-interferon/ribavirin combination therapy for patients with genotype 1 hepatitis C virus infection: A randomized controlled study.
Hepatitis C
Addition of ribavirin to daclatasvir plus asunaprevir for chronic hepatitis C 1b patients with baseline NS5A resistance-associated variants improved response.
Hepatitis C
An update on the management of hepatitis C: consensus guidelines from the Canadian Association for the Study of the Liver.
Hepatitis C
An update on the management of hepatitis C: guidelines for protease inhibitor-based triple therapy from the Latin American Association for the Study of the Liver.
Hepatitis C
An update on the toxicological considerations for protease inhibitors used for hepatitis C infection.
Hepatitis C
An update on the treatment of genotype-1 chronic hepatitis C infection: lessons from recent clinical trials.
Hepatitis C
Analysis of aptamer binding site for HCV-NS3 protease by alanine scanning mutagenesis.
Hepatitis C
Analysis of Hepatitis C Virus Decline during Treatment with the Protease Inhibitor Danoprevir Using a Multiscale Model.
Hepatitis C
Analysis of Naturally Occurring Resistance-Associated Variants to NS3/4A Protein Inhibitors, NS5A Protein Inhibitors, and NS5B Polymerase Inhibitors in Patients With Chronic Hepatitis C.
Hepatitis C
Analysis of NS3-mediated processing of the hepatitis C virus non-structural region in vitro.
Hepatitis C
Analysis of the domain interactions between the protease and helicase of NS3 in dengue and hepatitis C virus.
Hepatitis C
Antioxidant and antiviral activities of lipophilic epigallocatechin gallate (EGCG) derivatives.
Hepatitis C
Antiviral Activity of Boceprevir Monotherapy in Treatment-Naive Subjects With Chronic Hepatitis C Genotype 2/3.
Hepatitis C
Antiviral activity of narlaprevir combined with ritonavir and pegylated interferon in chronic hepatitis C patients.
Hepatitis C
Antiviral effects of peginterferon alpha-2b and ribavirin following 24-week monotherapy of telaprevir in Japanese hepatitis C patients.
Hepatitis C
Antiviral efficacy of NS3-serine protease inhibitor BILN-2061 in patients with chronic genotype 2 and 3 hepatitis C.
Hepatitis C
Antiviral resistance and the future landscape of hepatitis C virus infection therapy.
Hepatitis C
Antiviral suppression vs restoration of RIG-I signaling by hepatitis C protease and polymerase inhibitors.
Hepatitis C
Antiviral therapy of chronic hepatitis C in patients with advanced liver disease and after liver transplantation.
Hepatitis C
Apparent interaction between telaprevir and warfarin in a patient with chronic hepatitis C viral infection.
Hepatitis C
Application of the lambda-dynamics method to evaluate the relative binding free energies of inhibitors to HCV protease.
Hepatitis C
Approach to the treatment-experienced patient with hepatitis C virus genotype 1 infection.
Hepatitis C
Arthralgias and cryoglobulinemia during protease inhibitor therapy in a patient infected with human immunodeficiency virus and hepatitis C virus.
Hepatitis C
Association between exposure to nevirapine and reduced liver fibrosis progression in patients with HIV and hepatitis C virus coinfection.
Hepatitis C
Asunaprevir, a Potent Hepatitis C Virus Protease Inhibitor, Blocks SARS-CoV-2 Propagation.
Hepatitis C
Atorvastatin and Aspirin as Adjuvant Therapy in Patients with SARS-CoV-2 Infection: A structured summary of a study protocol for a randomised controlled trial.
Hepatitis C
Azetidines and spiro azetidines as novel P2 units in hepatitis C virus NS3 protease inhibitors.
Hepatitis C
Baseline Polymorphisms and Emergence of Drug Resistance in the NS3/4A Protease of Hepatitis C Virus Genotype 1 following Treatment with Faldaprevir and Pegylated Interferon Alpha 2a/Ribavirin in Phase 2 and Phase 3 Studies.
Hepatitis C
Benzothiazole and Pyrrolone Flavivirus Inhibitors Targeting the Viral Helicase.
Hepatitis C
Beyond telaprevir and boceprevir: resistance and new agents for hepatitis C virus infection.
Hepatitis C
Biliverdin inhibits hepatitis C virus nonstructural 3/4A protease activity: mechanism for the antiviral effects of heme oxygenase?
Hepatitis C
Binding of a noncovalent inhibitor exploiting the S' region stabilizes the hepatitis C virus NS3 protease conformation in the absence of cofactor.
Hepatitis C
Bioactive anthraquinones from endophytic fungus Aspergillus versicolor isolated from red sea algae.
Hepatitis C
Bioprospecting endophytic fungi from Fusarium genus as sources of bioactive metabolites.
Hepatitis C
Biotransformation and mass balance of faldaprevir, a hepatitis C NS3/NS4 protease inhibitor in rats.
Hepatitis C
Boceprevir and Antiretroviral Pharmacokinetic Interactions in HIV/HCV Co-infected Persons: AIDS Clinical Trials Group Study A5309s.
Hepatitis C
Boceprevir for previously untreated patients with chronic hepatitis C Genotype 1 infection: a US-based cost-effectiveness modeling study.
Hepatitis C
Boceprevir: a novel nonstructural 3 (NS3) protease inhibitor for the treatment of chronic hepatitis C infection.
Hepatitis C
Boceprevir: A Protease Inhibitor for the Treatment of Chronic Hepatitis C (September).
Hepatitis C
Boceprevir: a recently approved protease inhibitor for hepatitis C virus infection.
Hepatitis C
Both NS3 and NS4A are required for proteolytic processing of hepatitis C virus nonstructural proteins.
Hepatitis C
Can the Abbott RealTime hepatitis C virus assay be used to predict therapeutic outcomes in hepatitis C virus-infected patients undergoing triple therapy?
Hepatitis C
Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus.
Hepatitis C
Cardif: A protein central to innate immunity is inactivated by the HCV NS3 serine protease.
Hepatitis C
Challenges in modern drug discovery: a case study of boceprevir, an HCV protease inhibitor for the treatment of hepatitis C virus infection.
Hepatitis C
Characterisation of healthy donor-derived T-cell responses specific to telaprevir diastereomers.
Hepatitis C
Characterization and mutational analysis of the helicase and NTPase activities of hepatitis C virus full-length NS3 protein.
Hepatitis C
Characterization of clinical predictors of naturally occurring NS3/NS4A protease polymorphism in genotype 1 hepatitis C virus mono and HIV co-infected patients.
Hepatitis C
Characterization of human liver enzymes involved in the biotransformation of boceprevir, a hepatitis C virus protease inhibitor.
Hepatitis C
Characterization of mimotopes mimicking an immunodominant conformational epitope on the hepatitis C virus NS3 helicase.
Hepatitis C
Characterization of naturally occurring protease inhibitor-resistance mutations in genotype 1b hepatitis C virus patients.
Hepatitis C
Characterization of resistance to the protease inhibitor boceprevir in hepatitis C virus-infected patients.
Hepatitis C
Characterization of Resistance to the Protease Inhibitor GS-9451 in Hepatitis C Virus-Infected Patients.
Hepatitis C
CHARACTERIZATION OF V36C, A NOVEL AMINO ACID SUBSTITUTION CONFERRING HEPATITIS C VIRUS (HCV) RESISTANCE TO TELAPREVIR, A POTENT PEPTIDOMIMETIC INHIBITOR OF HCV PROTEASE.
Hepatitis C
Chronic hepatitis C: treat or wait? A prospective study on reasons for treatment or nontreatment in the era of first-generation protease inhibitors.
Hepatitis C
Circular dichroism analysis for multidomain proteins: studies of the irreversible unfolding of Hepatitis C virus helicase.
Hepatitis C
Class A Scavenger Receptor-Mediated Double-Stranded RNA Internalization Is Independent of Innate Antiviral Signaling and Does Not Require Phosphatidylinositol 3-Kinase Activity.
Hepatitis C
Classification Models of HCV NS3 Protease Inhibitors Based on Support Vector Machine (SVM).
Hepatitis C
Cleavage of the T cell protein tyrosine phosphatase by the hepatitis C virus nonstructural 3/4A protease induces a Th1 to Th2 shift reversible by ribavirin therapy.
Hepatitis C
Clinical assessment of potential drug interactions of faldaprevir, a hepatitis C virus protease inhibitor, with darunavir/ritonavir, efavirenz, and tenofovir.
Hepatitis C
Clinical pharmacology profile of boceprevir, a hepatitis C virus NS3 protease inhibitor: focus on drug-drug interactions.
Hepatitis C
Clinical trial simulation to evaluate power to compare the antiviral effectiveness of two hepatitis C protease inhibitors using nonlinear mixed effect models: a viral kinetic approach.
Hepatitis C
Combination treatment with hepatitis C virus protease and NS5A inhibitors is effective against recombinant genotype 1a, 2a, and 3a viruses.
Hepatitis C
Comparative effectiveness of the hepatitis C virus protease inhibitors boceprevir and telaprevir in a large U.S. cohort.
Hepatitis C
Comparative molecular dynamics simulation of Hepatitis C Virus NS3/4A protease (Genotypes 1b, 3a and 4b) predicts conformational instability of the catalytic triad in drug resistant strains.
Hepatitis C
Comparative peptide mapping of a hepatitis C viral recombinant protein by capillary electrophoresis and matrix-assisted laser desorption time-of-flight mass spectrometry.
Hepatitis C
Complex formation between the hepatitis C virus serine protease and a synthetic NS4A cofactor peptide.
Hepatitis C
Computational drug repurposing study elucidating simultaneous inhibition of entry and replication of novel corona virus by Grazoprevir.
Hepatitis C
Construction of hepatitis C-SIN virus recombinants with replicative dependency on hepatitis C virus serine protease activity.
Hepatitis C
Construction of the dual-functional RNA ligand against HCV NS3 protease and helicase.
Hepatitis C
Construction, expression, and characterization of a novel fully activated recombinant single-chain hepatitis C virus protease.
Hepatitis C
Correlation between PAMPA permeability and cellular activities of hepatitis C virus protease inhibitors.
Hepatitis C
Cost Effectiveness of Daclatasvir/Asunaprevir Versus Peginterferon/Ribavirin and Protease Inhibitors for the Treatment of Hepatitis c Genotype 1b Naïve Patients in Chile.
Hepatitis C
Cost of Adverse Drug Reactions (ADR) with Protease Inhibitors in the Treatment of Hepatitis C in the Health System of Extremadura (SES).
Hepatitis C
Cost-Effectiveness Analysis of Triple Therapy with Protease Inhibitors in Treatment-Naive Hepatitis C Patients.
Hepatitis C
Cost-effectiveness of IL28? genotype-guided protease inhibitor triple therapy versus standard of care treatment in patients with hepatitis C genotypes 2 or 3 infection.
Hepatitis C
Cost-effectiveness of Oral Protease Inhibitors Co-administration versus Pegylated Interferon-?2b and Ribavirin Only for the Patients with Hepatitis C Genotype 1 in Kazakhstan Health Care Settings.
Hepatitis C
Cost-effectiveness of sofosbuvir for the treatment of chronic hepatitis C-infected patients.
Hepatitis C
Cost-effectiveness of telaprevir in patients with genotype 1 hepatitis C in Australia.
Hepatitis C
Coumarins and Quinolones as Effective Multiple Targeted Agents Versus Covid-19: An in Silico Study.
Hepatitis C
Cross-genotypic interaction between hepatitis C virus NS3 protease domains and NS4A cofactors.
Hepatitis C
Crowded environment affects the activity and inhibition of the NS3/4A protease.
Hepatitis C
Crystal structure and activity of Kunjin virus NS3 helicase; protease and helicase domain assembly in the full length NS3 protein.
Hepatitis C
Crystal structure of a novel dimeric form of NS5A domain I protein from hepatitis C virus.
Hepatitis C
Cyclic sulfones as novel P3-caps for hepatitis C virus NS3/4A (HCV NS3/4A) protease inhibitors: synthesis and evaluation of inhibitors with improved potency and pharmacokinetic profiles.
Hepatitis C
Daclatasvir plus simeprevir with or without ribavirin for the treatment of chronic hepatitis C virus genotype 1 infection.
Hepatitis C
Danoprevir monotherapy decreases inflammatory markers in patients with chronic hepatitis C virus infection.
Hepatitis C
DAUPHINE: a randomized phase II study of danoprevir/ritonavir plus peginterferon alpha-2a/ribavirin in HCV genotypes 1 or 4.
Hepatitis C
Deep sequencing and phylogenetic analysis of variants resistant to interferon-based protease inhibitor therapy in chronic hepatitis induced by genotype 1b hepatitis C virus.
Hepatitis C
Deep-Sequencing Analysis of the Gene Encoding the Hepatitis C Virus Nonstructural 3-4A Protease Confirms a Low Prevalence of Telaprevir-Resistant Variants at Baseline and the End of the REALIZE Study.
Hepatitis C
Dermatological adverse effects during genotype-1 hepatitis C treatment with the protease inhibitors telaprevir and boceprevir. Patient management.
Hepatitis C
Design, high-level expression, purification and characterization of soluble fragments of the hepatitis C virus NS3 RNA helicase suitable for NMR-based drug discovery methods and mechanistic studies.
Hepatitis C
Designing and analysis of a potent bi-functional aptamers that inhibit protease and helicase activities of HCV NS3.
Hepatitis C
Despite poor interferon response in advanced hepatitis C virus infection, models of protease inhibitor treatment predict maximum treatment benefit.
Hepatitis C
Detection of a sexually transmitted hepatitis C virus protease inhibitor-resistance variant in a human immunodeficiency virus-infected homosexual man.
Hepatitis C
Detection of the NS3 Q80K polymorphism by Sanger and deep sequencing in hepatitis C virus genotype 1a strains in the UK.
Hepatitis C
Determinants for Membrane Association of the Hepatitis C Virus NS2 Protease Domain.
Hepatitis C
Determinants of hepatitis C virus nonstructural protein 2 protease domain required for production of infectious virus.
Hepatitis C
Determination of simeprevir: A novel, hepatitis C protease inhibitor in human plasma by high-performance liquid chromatography-tandem mass spectrometry.
Hepatitis C
Determination of the HCV protease inhibitor telaprevir in plasma and dried blood spot by liquid chromatography tandem mass spectrometry.
Hepatitis C
Development of a cell-based assay for monitoring hepatitis C virus ns3/4a protease activity.
Hepatitis C
Development of a high-throughput pyrosequencing assay for monitoring temporal evolution and resistance associated variant emergence in the Hepatitis C virus protease coding-region.
Hepatitis C
Development of a Practical, Asymmetric Synthesis of the Hepatitis C Virus Protease Inhibitor MK-5172.
Hepatitis C
Development of a replicon-based phenotypic assay for assessing the drug susceptibilities of HCV NS3 protease genes from clinical isolates.
Hepatitis C
Development of a simple HPLC-UV method for the determination of the hepatitis C virus inhibitor simeprevir in human plasma.
Hepatitis C
Development of an intergenotypic hepatitis C virus (HCV) cell culture method to assess antiviral susceptibilities and resistance development of HCV NS3 protease genes from HCV genotypes 1 to 6.
Hepatitis C
Development of an on-line automated sample clean-up method and liquid chromatography-tandem mass spectrometry analysis: application in an in vitro proteolytic assay.
Hepatitis C
Development of antiviral drugs for the treatment of hepatitis C at an accelerating pace.
Hepatitis C
Development of boceprevir: a first-in-class direct antiviral treatment for chronic hepatitis C infection.
Hepatitis C
Differential requirements of NS4A for internal NS3 cleavage and polyprotein processing of hepatitis C virus.
Hepatitis C
Differential sensitivity of 5'UTR-NS5A recombinants of hepatitis C virus genotypes 1-6 to protease and NS5A inhibitors.
Hepatitis C
Differential, type I interferon-mediated autophagic trafficking of hepatitis C virus proteins in mouse liver.
Hepatitis C
Direct acting antivirals for the treatment of chronic hepatitis C: one pill a day for tomorrow.
Hepatitis C
Direct-acting antivirals for the treatment of chronic hepatitis C: open issues and future perspectives.
Hepatitis C
Discovery and development of VX-950, a novel, covalent, and reversible inhibitor of hepatitis C virus NS3.4A serine protease.
Hepatitis C
Discovery of an allosteric mechanism for the regulation of HCV NS3 protein function.
Hepatitis C
Discovery of novel urea-based hepatitis C protease inhibitors with high potency against protease-inhibitor-resistant mutants.
Hepatitis C
Disorders of glucose metabolism in the context of human immunodeficiency virus infection.
Hepatitis C
Distribution of natural resistance to NS3 protease inhibitors in hepatitis C genotype 1a separated into clades 1 and 2 and in genotype 1b of HIV-infected patients.
Hepatitis C
DNA immunization efficiently targets conserved functional domains of protease and ATPase/helicase of nonstructural 3 protein (NS3) of human hepatitis C virus.
Hepatitis C
Does boceprevir really increase the risk of skin eruptions during antihepatitis C treatment?
Hepatitis C
Dose- and Formulation-Dependent Non-Linear Pharmacokinetic Model of Paritaprevir, a Protease Inhibitor for the Treatment of Hepatitis C Virus Infection: Combined Analysis from 12 Phase I Studies.
Hepatitis C
Double-stranded RNA-induced interferon-beta and inflammatory cytokine production modulated by hepatitis C virus serine proteases derived from patients with hepatic diseases.
Hepatitis C
Drug interactions and protease inhibitors used in the treatment of hepatitis C: how to manage?
Hepatitis C
Dual therapy with the nonstructural protein 5A inhibitor, daclatasvir, and the nonstructural protein 3 protease inhibitor, asunaprevir, in hepatitis C virus genotype 1b-infected null responders.
Hepatitis C
Dutch guidance for the treatment of chronic hepatitis C virus infection in a new therapeutic era.
Hepatitis C
Dynamic changes in HCV RNA levels and viral quasispecies in a patient with chronic hepatitis C after telaprevir-based treatment.
Hepatitis C
Dynamic hepatitis C virus genotypic and phenotypic changes in patients treated with the protease inhibitor telaprevir.
Hepatitis C
Ebselen inhibits hepatitis C virus NS3 helicase binding to nucleic acid and prevents viral replication.
Hepatitis C
Effect of disease state on ionization during bioanalysis of MK-7009, a selective HCV NS3/NS4 protease inhibitor, in human plasma and human Tween-treated urine by high-performance liquid chromatography with tandem mass spectrometric detection.
Hepatitis C
Effect of Hepatic Impairment on the Pharmacokinetics of Grazoprevir, a Hepatitis C Virus Protease Inhibitor.
Hepatitis C
Effect of IL28B Genotype on Early Viral Kinetics During Interferon-Free Treatment of Patients With Chronic Hepatitis C.
Hepatitis C
Effect of itraconazole on the pharmacokinetics of faldaprevir in healthy subjects.
Hepatitis C
Effect of Ritonavir-Boosted Danoprevir, a Potent Hepatitis C Virus Protease Inhibitor, on the Pharmacokinetics of Methadone in Healthy Subjects Undergoing Methadone Maintenance Therapy.
Hepatitis C
Effect of Steady-State Faldaprevir on Pharmacokinetics of Atorvastatin or Rosuvastatin in Healthy Volunteers: A Prospective Open-Label, Fixed-Sequence Crossover Study.
Hepatitis C
Effect of the hepatitis C virus protease inhibitor faldaprevir on the pharmacokinetics of an oral contraceptive containing ethinylestradiol and levonorgestrel in healthy female volunteers.
Hepatitis C
Effect of the hepatitis C virus protease inhibitor telaprevir on the pharmacokinetics of amlodipine and atorvastatin.
Hepatitis C
Effectiveness and safety of first-generation protease inhibitors in clinical practice: Hepatitis C virus patients with advanced fibrosis.
Hepatitis C
Effectiveness and safety of first-generation protease inhibitors in real-world patients with hepatitis C virus genotype 1 infection in Brazil: a multicenter study.
Hepatitis C
Effectiveness of first-wave protease inhibitors in hepatitis C virus genotype 1 infection: a multicenter study in Brazil.
Hepatitis C
Effectiveness of Telaprevir or Boceprevir in Treatment-experienced Patients with HCV Genotype 1 Infection and Cirrhosis.
Hepatitis C
Effects of Smoking on Pegylated Interferon alpha 2a and First Generation Protease Inhibitor-based Antiviral Therapy in Naïve Patients Infected with Hepatitis C Virus Genotype 1.
Hepatitis C
Effects on protease inhibition by modifying of helicase residues in hepatitis C virus nonstructural protein 3.
Hepatitis C
Efficacy and safety of danoprevir-ritonavir plus peginterferon alfa-2a-ribavirin in hepatitis C virus genotype 1 prior null responders.
Hepatitis C
Efficacy and Safety of Glecaprevir/Pibrentasvir in Japanese Patients with Chronic Genotype 2 Hepatitis C Virus Infection.
Hepatitis C
Efficacy of boceprevir, an NS3 protease inhibitor, in combination with peginterferon alfa-2b and ribavirin in treatment-naive patients with genotype 1 hepatitis C infection (SPRINT-1): an open-label, randomised, multicentre phase 2 trial.
Hepatitis C
Efficacy of lead-in silibinin and subsequent triple therapy in difficult-to-treat HIV/hepatitis C virus-coinfected patients.
Hepatitis C
Efficacy of Re-treatment With TMC435 as Combination Therapy in Hepatitis C Virus-Infected Patients Following TMC435 Monotherapy.
Hepatitis C
Efficient Hepatitis C Virus Genotype 1b Core-NS5A Recombinants Permit Efficacy Testing of Protease and NS5A Inhibitors.
Hepatitis C
Efficient large-scale synthesis of BILN 2061, a potent HCV protease inhibitor, by a convergent approach based on ring-closing metathesis.
Hepatitis C
Eligibility and safety of the first interferon-free therapy against hepatitis C in a real-world setting.
Hepatitis C
Engineering of TEV protease variants by yeast ER sequestration screening (YESS) of combinatorial libraries.
Hepatitis C
Enhanced nucleic acid binding to ATP-bound hepatitis C virus NS3 helicase at low pH activates RNA unwinding.
Hepatitis C
Enzymatic characterization and homology model of a catalytically active recombinant West Nile virus NS3 protease.
Hepatitis C
Enzymatic characterization of hepatitis C virus NS3/4A complexes expressed in mammalian cells by using the herpes simplex virus amplicon system.
Hepatitis C
Enzymatic characterization of membrane-associated hepatitis C virus NS3-4A heterocomplex serine protease activity expressed in human cells.
Hepatitis C
Enzyme-transporter interplay in the formation and clearance of abundant metabolites of faldaprevir found in excreta but not in circulation.
Hepatitis C
Epoxide based inhibitors of the hepatitis C virus non-structural 2 autoprotease.
Hepatitis C
Erratum for Wire et al., Lack of clinically significant pharmacokinetic interaction between the thrombopoietin receptor agonist eltrombopag and hepatitis C virus protease inhibitors boceprevir and telaprevir.
Hepatitis C
Establishment and application of high throughput screening model for hepatitis C virus NS3-4A protease inhibitors in vitro.
Hepatitis C
Establishment of a cell-based assay system for hepatitis C virus serine protease and its primary applications.
Hepatitis C
Establishment of a simple assay in vitro for hepatitis C virus NS3 serine protease based on recombinant substrate and single-chain protease.
Hepatitis C
Establishment of an in vitro assay system for screening hepatitis C virus protease inhibitors using high performance liquid chromatography.
Hepatitis C
Estimates of HCV-1 Patients Attaining RVR Following Dual Therapy with Peg-Interferon and Ribavirin.
Hepatitis C
Ethical assessment of hepatitis C virus treatment: The lesson from first generation protease inhibitors.
Hepatitis C
Evaluating the Role of Cellular Immune Responses in the Emergence of HCV NS3 Resistance Mutations During Protease Inhibitor Therapy.
Hepatitis C
Evaluation of advanced fibrosis measured by transient elastography after hepatitis C virus protease inhibitor-based triple therapy.
Hepatitis C
Evaluation of Statin Eligibility, Prescribing Practices, and Therapeutic Responses Using ATP III, ACC/AHA, and NLA Dyslipidemia Treatment Guidelines in a Large Urban Cohort of HIV-Infected Outpatients.
Hepatitis C
Evaluation of the Pharmacokinetics and Renal Excretion of Simeprevir in Subjects with Renal Impairment.
Hepatitis C
Evolution of plasma hepatitis C virus load in patients coinfected by HIV and hepatitis C Virus started on a protease inhibitor-containing antiretroviral regimen, Agence Nationale de Recherches sur le SIDA CO8 APROCO-COPILOTE cohort.
Hepatitis C
Evolution of the NS3 and NS5B regions of the hepatitis C virus during disease recurrence after liver transplantation.
Hepatitis C
Evolution, synthesis and SAR of tripeptide alpha-ketoacid inhibitors of the hepatitis C virus NS3/NS4A serine protease.
Hepatitis C
Evolutionary Pathways to Persistence of Highly Fit and Resistant Hepatitis C Virus Protease Inhibitor Escape Variants.
Hepatitis C
Exploiting Dengue Virus Protease as a Therapeutic Target; Current Status, Challenges and Future Avenues.
Hepatitis C
Exploration of acyl sulfonamides as carboxylic acid replacements in protease inhibitors of the hepatitis C virus full-length NS3.
Hepatitis C
Expression and purification of hepatitis C virus protease from clinical samples.
Hepatitis C
Factors affecting liver fibrosis in human immunodeficiency virus-and hepatitis C virus-coinfected patients: impact of protease inhibitor therapy.
Hepatitis C
Factors that predict response of patients with hepatitis C virus infection to boceprevir.
Hepatitis C
Favorable adverse event profile of sofosbuvir/ribavirin compared to boceprevir/interferon/ribavirin for treatment of hepatitis C.
Hepatitis C
First clinical study using HCV protease inhibitor danoprevir to treat COVID-19 patients.
Hepatitis C
First-wave protease inhibitors for hepatitis C genotype 1 treatment: a real-life experience in Brazilian patients.
Hepatitis C
Fluorescent primuline derivatives inhibit hepatitis C virus NS3-catalyzed RNA unwinding, peptide hydrolysis and viral replicase formation.
Hepatitis C
Formulary management of the protease inhibitors boceprevir and telaprevir for chronic hepatitis C virus.
Hepatitis C
Fragment-based development of HCV protease inhibitors for the treatment of hepatitis C.
Hepatitis C
From first-generation hepatitis C virus protease inhibitors to direct-acting antivirals: self-reported symptoms as a warning signal for potential adverse events (ANRS HC26, ANRS HC27 trials).
Hepatitis C
Functional and therapeutic analysis of hepatitis C virus NS3.4A protease control of antiviral immune defense.
Hepatitis C
Future treatment options for HCV: double, triple, what is the optimal combination?
Hepatitis C
Generating an in vitro-in vivo correlation for metabolism and liver enrichment of a hepatitis C virus drug, faldaprevir, using a rat hepatocyte model (HepatoPac).
Hepatitis C
Generation of a novel poliovirus with a requirement of hepatitis C virus protease NS3 activity.
Hepatitis C
Genetic diversity and response to IFN of the NS3 protease gene from clinical strains of the hepatitis C virus.
Hepatitis C
Genome-wide association study to characterize serum bilirubin elevations in patients with HCV treated with GS-9256, an HCV NS3 serine protease inhibitor.
Hepatitis C
Genotype differences in susceptibility and resistance development of hepatitis C virus to protease inhibitors telaprevir (VX-950) and danoprevir (ITMN-191).
Hepatitis C
Glecaprevir and pibrentasvir for Japanese patients with chronic hepatitis C genotype 1 or 2 infection: Results from a multicenter, real-world cohort study.
Hepatitis C
Grazoprevir/elbasvir for the treatment of adults with chronic hepatitis C: a short review on the clinical evidence and place in therapy.
Hepatitis C
HCV genotype 1-6 NS3 residue 80 substitutions impact protease inhibitor activity and promote viral escape.
Hepatitis C
HCV NS3Ag: a reliable and clinically useful predictor of antiviral outcomes in genotype 1b hepatitis C virus-infected patients.
Hepatitis C
HCV-NS3/4A protease inhibitory iridoid glucosides and dimeric foliamenthoic acid derivatives from Anarrhinum orientale.
Hepatitis C
Hepatitis B and C virus co-infection and the risk for hepatotoxicity of highly active antiretroviral therapy in HIV-1 infection.
Hepatitis C
Hepatitis B and Hepatitis C virus replication up-regulate serine protease inhibitor Kazal, resulting in cellular resistance to serine protease dependent apoptosis.
Hepatitis C
Hepatitis B or hepatitis C virus infection is a risk factor for severe hepatic cytolysis after initiation of a protease inhibitor-containing antiretroviral regimen in human immunodeficiency virus-infected patients. The APROCO Study Group.
Hepatitis C
Hepatitis C genotype 1 virus with low viral load and rapid virologic response to peginterferon/ribavirin obviates a protease inhibitor.
Hepatitis C
Hepatitis C NS3 protease inhibition by peptidyl-alpha-ketoamide inhibitors: kinetic mechanism and structure.
Hepatitis C
Hepatitis C reinfection with protease inhibitor-resistant hepatitis C virus in an HIV-coinfected MSM.
Hepatitis C
Hepatitis C virus (HCV) protease variability and anti-HCV protease inhibitor resistance in HIV/HCV-coinfected patients.
Hepatitis C
Hepatitis C virus and human immunodeficiency virus: clinical issues in coinfection.
Hepatitis C
Hepatitis C virus directly acting antivirals: current developments with NS3/4A HCV serine protease inhibitors.
Hepatitis C
Hepatitis C virus drug resistance and immune-driven adaptations: relevance to new antiviral therapy.
Hepatitis C
Hepatitis C Virus Genotype 1-6 Protease Inhibitor Escape Variants: In Vitro Selection, Fitness and Resistance Patterns in the Context of the Infectious Viral Life Cycle.
Hepatitis C
Hepatitis C virus non-structural protein 3 (HCV NS3): a multifunctional antiviral target.
Hepatitis C
Hepatitis C virus NS2 protease inhibits host cell antiviral response by inhibiting IKK? and TBK1 functions.
Hepatitis C
Hepatitis C virus NS3 NTPase/helicase: different stereoselectivity in nucleoside triphosphate utilisation suggests that NTPase and helicase activities are coupled by a nucleotide-dependent rate limiting step.
Hepatitis C
Hepatitis C virus NS3 protease is activated by low concentrations of protease inhibitors.
Hepatitis C
Hepatitis C virus NS3 protein interacts with ELKS-{delta} and ELKS-{alpha}, members of a novel protein family involved in intracellular transport and secretory pathways.
Hepatitis C
Hepatitis C Virus NS3 Protein Plays a Dual Role in WRN-Mediated Repair of Non-Homologous End Joining.
Hepatitis C
Hepatitis C virus NS3-4A protease inhibitors: countering viral subversion in vitro and showing promise in the clinic.
Hepatitis C
Hepatitis C virus NS4B protein targets STING and abrogates RIG-I-mediated type-I interferon-dependent innate immunity.
Hepatitis C
Hepatitis C virus NS5A and subgenomic replicon activate NF-kappaB via tyrosine phosphorylation of IkappaBalpha and its degradation by calpain protease.
Hepatitis C
Hepatitis C virus protease gene diversity in patients coinfected with human immunodeficiency virus.
Hepatitis C
Hepatitis C virus protease inhibitor-resistance mutations: our experience and review.
Hepatitis C
Hepatitis C Virus Protease Inhibitors Show Differential Efficacy and Interactions with Remdesivir for Treatment of SARS-CoV-2 In Vitro.
Hepatitis C
Hepatitis C virus protease NS3/4A cleaves mitochondrial antiviral signaling protein off the mitochondria to evade innate immunity.
Hepatitis C
Hepatitis C virus serine protease: synthesis of radioactive and stable isotope-labeled potent inhibitors.
Hepatitis C
Hepatitis C virus treatment and liver transplantation in the era of new antiviral therapies.
Hepatitis C
Hepatitis C virus-encoded NS2-3 protease: cleavage-site mutagenesis and requirements for bimolecular cleavage.
Hepatitis C
Hepatitis C, disease and its management: a cost-effectiveness analysis of the new generation oral protease inhibitors.
Hepatitis C
Hepatotoxicity associated with antiretroviral therapy containing dual versus single protease inhibitors in individuals coinfected with hepatitis C virus and human immunodeficiency virus.
Hepatitis C
Hepatotoxicity associated with antiretroviral therapy in adults infected with human immunodeficiency virus and the role of hepatitis C or B virus infection.
Hepatitis C
High Efficacy of ABT-493 and ABT-530 Treatment in Patients With HCV Genotype 1 or 3 Infection and Compensated Cirrhosis.
Hepatitis C
High hepatitis C virus viral load in HIV/hepatitis C virus-co-infected patients: a different influence of protease inhibitor and non-protease inhibitor-based HAART?
Hepatitis C
High post-transplant virological response in hepatitis C virus infected patients treated with pretransplant protease inhibitor-based triple therapy.
Hepatitis C
Highly potent and selective peptide-based inhibitors of the hepatitis C virus serine protease: towards smaller inhibitors.
Hepatitis C
Highly sensitive determination of HCV protease inhibitors boceprevir (SCH 503034) and telaprevir (VX 950) in human plasma by LC-MS/MS.
Hepatitis C
HIV-HCV co-infection facing HCV protease inhibitor licensing: implications for clinicians.
Hepatitis C
How to find simple and accurate rules for viral protease cleavage specificities.
Hepatitis C
Human and murine antibody recognition is focused on the ATPase/helicase, but not the protease domain of the hepatitis C virus nonstructural 3 protein.
Hepatitis C
Human immunodeficiency virus (HIV) protease inhibitors have no effect on hepatitis C virus (HCV) serum levels of HIV-HCV co-infected patients.
Hepatitis C
Human pegivirus (GB virus C) NS3 protease activity inhibits induction of the type I interferon response and is not inhibited by HCV NS3 protease inhibitors.
Hepatitis C
Hyperbilirubinaemia in HIV-HCV co-infected patients on antiretroviral therapy: drug effect or liver disease severity?
Hepatitis C
Hypogonadotropic hypogonadism in human immunodeficiency virus-infected men: uncommonly low testosterone levels.
Hepatitis C
Identification and analysis of fitness of resistance mutations against the HCV protease inhibitor SCH 503034.
Hepatitis C
Identification of novel small molecules as inhibitors of hepatitis C virus by structure-based virtual screening.
Hepatitis C
Impact of adverse events on costs and quality of life in protease inhibitor-based combination therapy for hepatitis C.
Hepatitis C
Impact of hepatitis C triple therapy availability upon the number of patients to be treated and associated costs in France: a model-based analysis.
Hepatitis C
Impact of highly active antiretroviral therapy on hepatitis C virus protease quasispecies diversity in HIV co-infected patients.
Hepatitis C
Impact of interferon-ribavirin treatment on hepatitis C virus (HCV) protease quasispecies diversity in HIV- and HCV-coinfected patients.
Hepatitis C
Impact of specialty pharmacy on telaprevir-containing 3-drug hepatitis C regimen persistence.
Hepatitis C
Impact of treatment with human immunodeficiency virus (HIV) protease inhibitors on hepatitis C viremia in patients coinfected with HIV.
Hepatitis C
In silico identification of available drugs targeting cell surface BiP to disrupt SARS-CoV-2 binding and replication: Drug repurposing approach.
Hepatitis C
In trans interaction of hepatitis C virus helicase domains mediates protease activity critical for internal NS3 cleavage and cell transformation.
Hepatitis C
In vitro activity and preclinical profile of TMC435350, a potent hepatitis C virus protease inhibitor.
Hepatitis C
In vitro activity of hepatitis C virus protease NS3 purified from recombinant Baculovirus-infected Sf9 cells.
Hepatitis C
In vitro and in vivo isotope effects with hepatitis C protease inhibitors: enhanced plasma exposure of deuterated telaprevir versus telaprevir in rats.
Hepatitis C
In vitro assessment of drug-drug interaction potential of boceprevir associated with drug metabolizing enzymes and transporters.
Hepatitis C
In Vitro Assessment of Re-treatment Options for Patients with Hepatitis C Virus Genotype 1b Infection Resistant to Daclatasvir Plus Asunaprevir.
Hepatitis C
In vitro inhibition of Hepatitis C virus protease and antioxidant by flavonoid glycosides from the Saudi costal plant Sarcocornia fruticosa.
Hepatitis C
In Vitro Phenotypic Characterization of Hepatitis C Virus NS3 Protease Variants Observed in Clinical Studies of Telaprevir.
Hepatitis C
In vitro resistance studies of hepatitis C virus serine protease inhibitors, VX-950 and BILN 2061: structural analysis indicates different resistance mechanisms.
Hepatitis C
In vitro selection and characterization of hepatitis C virus serine protease variants resistant to an active-site peptide inhibitor.
Hepatitis C
In vitro studies of cross-resistance mutations against two hepatitis C virus serine protease inhibitors, VX-950 and BILN 2061.
Hepatitis C
In vivo assay for hepatitis C viral serine protease activity using a secreted protein.
Hepatitis C
In vivo selection of protease cleavage sites by using chimeric Sindbis virus libraries.
Hepatitis C
In-cell selectivity profiling of membrane-anchored and replicase-associated hepatitis C virus NS3-4A protease reveals a common, stringent substrate recognition profile.
Hepatitis C
Induction of cell-mediated immune responses in mice by DNA vaccines that express hepatitis C virus NS3 mutants lacking serine protease and NTPase/RNA helicase activities.
Hepatitis C
Inflammatory markers neopterin and alanine aminotransferase in HCV patients treated with HCV NS3.4A protease inhibitor telaprevir (VX-950) and/or peginterferon alfa-2a.
Hepatitis C
Influence of ABCC2 and ABCC4 polymorphisms on tenofovir plasma concentrations in Thai HIV-infected patients.
Hepatitis C
Inhibition and Binding Kinetics of the Hepatitis C Virus NS3 Protease Inhibitor ITMN-191 Reveals Tight Binding and Slow Dissociative Behavior.
Hepatitis C
Inhibition of both protease and helicase activities of hepatitis C virus NS3 by an ethyl acetate extract of marine sponge Amphimedon sp.
Hepatitis C
Inhibition of hepatitis C virus nonstructural protein, helicase activity, and viral replication by a recombinant human antibody clone.
Hepatitis C
Inhibition of hepatitis C virus NS3 function by antisense oligodeoxynucleotides and protease inhibitor.
Hepatitis C
Inhibition of hepatitis C virus serine protease in living cells by RNA aptamers detected using fluorescent protein substrates.
Hepatitis C
Inhibition of sphingosine kinase by bovine viral diarrhea virus NS3 is crucial for efficient viral replication and cytopathogenesis.
Hepatitis C
Inhibition of the hepatitis C virus NS3/4A protease. The crystal structures of two protease-inhibitor complexes.
Hepatitis C
Inhibition of the Interaction Between NS3 Protease and HCV IRES With a Small Peptide: A Novel Therapeutic Strategy.
Hepatitis C
Inhibitors of hepatitis C virus NS3.4A protease 1. Non-charged tetrapeptide variants.
Hepatitis C
Inhibitors of hepatitis C virus NS3.4A protease 2. Warhead SAR and optimization.
Hepatitis C
Inhibitors of hepatitis C virus NS3.4A protease. Effect of P4 capping groups on inhibitory potency and pharmacokinetics.
Hepatitis C
Inhibitory effects of antrodins A-E from Antrodia cinnamomea and their metabolites on hepatitis C virus protease.
Hepatitis C
Inhibitory effects of sudanese medicinal plant extracts on hepatitis C virus (HCV) protease.
Hepatitis C
Insight into the Structural Requirements of Narlaprevir-type Inhibitors of NS3/NS4A Protease Based on HQSAR and Molecular Field Analyses.
Hepatitis C
Insights into resistance mechanism of hepatitis C virus nonstructural 3/4A protease mutant to boceprevir using umbrella sampling simulation study.
Hepatitis C
Interactions of the hepatitis C virus protease inhibitor faldaprevir with cytochrome P450 enzymes: In vitro and in vivo correlation.
Hepatitis C
Internal cleavage of hepatitis C virus NS3 protein is dependent on the activity of NS34A protease.
Hepatitis C
Intracellular Activation of Tenofovir Alafenamide and the Effect of Viral and Host Protease Inhibitors.
Hepatitis C
Isolation and characterization of RNA aptamers specific for the hepatitis C virus nonstructural protein 3 protease.
Hepatitis C
Isolation and structure of SCH 351633: a novel hepatitis C virus (HCV) NS3 protease inhibitor from the fungus Penicillium griseofulvum.
Hepatitis C
Isolation of specific and high-affinity RNA aptamers against NS3 helicase domain of hepatitis C virus.
Hepatitis C
Isosorbide-based peptidomimetics as inhibitors of hepatitis C virus serine protease.
Hepatitis C
Lack of a clinically significant drug-drug interaction in healthy volunteers between the hepatitis C virus protease inhibitor boceprevir and the HIV integrase inhibitor raltegravir.
Hepatitis C
Lack of clinically significant pharmacokinetic interaction between the thrombopoietin receptor agonist eltrombopag and hepatitis C virus protease inhibitors boceprevir and telaprevir.
Hepatitis C
Large-Scale Structure-Based Prediction and Identification of Novel Protease Substrates Using Computational Protein Design.
Hepatitis C
Lead Optimization in Discovery Drug Metabolism and Pharmacokinetics/Case study: The Hepatitis C Virus (HCV) Protease Inhibitor SCH 503034.
Hepatitis C
Limited effect on NS3-NS4A protein cleavage after alanine substitutions within the immunodominant HLA-A2-restricted epitope of the hepatitis C virus genotype 3a non-structural 3/4A protease.
Hepatitis C
Limited suppression of the interferon-beta production by hepatitis C virus serine protease in cultured human hepatocytes.
Hepatitis C
Liver injury and changes in hepatitis C Virus (HCV) RNA load associated with protease inhibitor-based antiretroviral therapy for treatment-naive HCV-HIV-coinfected patients: lopinavir-ritonavir versus nelfinavir.
Hepatitis C
Low Baseline CD4+ Count Is Associated With Greater Bone Mineral Density Loss After Antiretroviral Therapy Initiation.
Hepatitis C
Low dose and gene gun immunization with a hepatitis C virus nonstructural (NS) 3 DNA-based vaccine containing NS4A inhibit NS3/4A-expressing tumors in vivo.
Hepatitis C
Lyme disease: the promise of Big Data, companion diagnostics and precision medicine.
Hepatitis C
Malleability of the SARS-CoV-2 3CL Mpro Active-Site Cavity Facilitates Binding of Clinical Antivirals.
Hepatitis C
Mass Balance and Metabolite Profiling of Steady-State Faldaprevir, a Hepatitis C Virus NS3/4 Protease Inhibitor, in Healthy Male Subjects.
Hepatitis C
Mechanistic and kinetic characterization of hepatitis C virus NS3 protein interactions with NS4A and protease inhibitors.
Hepatitis C
Mechanistic studies of electrophilic protease inhibitors of full length hepatic C virus (HCV) NS3.
Hepatitis C
Metabolic Syndrome in French HIV-Infected Patients: Prevalence and Predictive Factors After 3 Years of Antiretroviral Therapy.
Hepatitis C
Metabolism and Disposition of the Hepatitis C Protease Inhibitor Paritaprevir in Humans.
Hepatitis C
Minor contribution of CYP3A5 to the metabolism of hepatitis C protease inhibitor paritaprevir in vitro.
Hepatitis C
MK-5172 : a second-generation protease inhibitor for the treatment of hepatitis C virus infection.
Hepatitis C
MK-5172, a Selective Inhibitor of Hepatitis C Virus NS3/4a Protease with Broad Activity across Genotypes and Resistant Variants.
Hepatitis C
Modeling quasispecies and drug resistance in hepatitis C patients treated with a protease inhibitor.
Hepatitis C
Modular cell-based platform for high throughput identification of compounds that inhibit a viral interferon antagonist of choice.
Hepatitis C
Modular Combination of Proteolysis-Responsive Transcription and Spherical Nucleic Acids for Smartphone-Based Colorimetric Detection of Protease Biomarkers.
Hepatitis C
Modulation of hepatitis C virus NS3 protease and helicase activities through the interaction with NS4A.
Hepatitis C
Molecular basis of telaprevir resistance due to V36 and T54 mutations in the NS3-4A protease of the hepatitis C virus.
Hepatitis C
Molecular characterization of hepatitis C virus for determination of subtypes and detection of resistance mutations to protease inhibitors in a group of intravenous drug users co-infected with HIV.
Hepatitis C
Molecular docking investigation of the binding interactions of macrocyclic inhibitors with HCV NS3 protease and its mutants (R155K, D168A and A156V).
Hepatitis C
Molecular Mechanism of Resistance in a Clinically Significant Double-Mutant Variant of HCV NS3/4A Protease.
Hepatitis C
Molecular model of the specificity pocket of the hepatitis C virus protease: implications for substrate recognition.
Hepatitis C
Multicenter Experience with Boceprevir or Telaprevir to Treat Hepatitis C Recurrence after Liver Transplantation: When Present Becomes Past, What Lessons for Future?
Hepatitis C
Multicenter quality control of hepatitis C virus protease inhibitor resistance genotyping.
Hepatitis C
Multiple enzymatic activities associated with recombinant NS3 protein of hepatitis C virus.
Hepatitis C
Mutations conferring resistance to a hepatitis C virus (HCV) RNA-dependent RNA polymerase inhibitor alone or in combination with an HCV serine protease inhibitor in vitro.
Hepatitis C
Mutations conferring resistance to a potent hepatitis C virus serine protease inhibitor in vitro.
Hepatitis C
Mutations in hepatitis C virus NS3 protease domain associated with resistance to specific protease inhibitors in antiviral therapy naïve patients.
Hepatitis C
Mycobacterium abscessus pulmonary infection during hepatitis C treatment with telaprevir, peginterferon and ribavirin.
Hepatitis C
N- t-Boc-amino acid esters of isomannide. Potential inhibitors of serine proteases.
Hepatitis C
Natural presence of NS3 protease R155K hepatitis C virus variants with decreased sensitivity to protease inhibitors.
Hepatitis C
Natural prevalence of hepatitis C virus (HCV) variants resistant to protease and polymerase inhibitors in patients infected with HCV genotype 1 in Tunisia.
Hepatitis C
Natural prevalence of hepatitis C virus variants with decreased sensitivity to NS3.4A protease inhibitors in treatment-naive subjects.
Hepatitis C
Naturally occurring dominant resistance mutations to hepatitis C virus protease and polymerase inhibitors in treatment-naïve patients.
Hepatitis C
Naturally occurring hepatitis C virus protease inhibitors resistance-associated mutations among chronic hepatitis C genotype 1b patients with or without HIV co-infection.
Hepatitis C
Naturally occurring mutations to HCV protease inhibitors in treatment-naïve patients.
Hepatitis C
Naturally Occurring Resistance-Associated Variants of Hepatitis C Virus Protease Inhibitors in Poor Responders to Pegylated Interferon-Ribavirin.
Hepatitis C
Near-Neighbor Interactions in the NS3-4A Protease of HCV Impact Replicative Fitness of Drug-Resistant Viral Variants.
Hepatitis C
Neutrophil and Monocyte Function in Patients with Chronic Hepatitis C Undergoing Antiviral Therapy with Regimens Containing Protease Inhibitors with and without Interferon.
Hepatitis C
New direct-acting antivirals' combination for the treatment of chronic hepatitis C.
Hepatitis C
New protease inhibitors and direct-acting antivirals for hepatitis C: interferon's long goodbye.
Hepatitis C
New resistance-associated substitutions and failure of dual oral therapy with daclatasvir and asunaprevir.
Hepatitis C
New treatment for hepatitis C in chronic kidney disease, dialysis, and transplant.
Hepatitis C
Nonstructural 3/4A protease of hepatitis C virus activates epithelial growth factor-induced signal transduction by cleavage of the T-cell protein tyrosine phosphatase.
Hepatitis C
Not so sweet: autoimmune diabetes mellitus on triple therapy for chronic hepatitis C infection.
Hepatitis C
Novel inhibitors of hepatitis C NS3-NS4A serine protease derived from 2-aza-bicyclo[2.2.1]heptane-3-carboxylic acid.
Hepatitis C
Novel protease and polymerase inhibitors for the treatment of hepatitis C virus infection.
Hepatitis C
NS2 proteins of GB virus B and hepatitis C virus share common protease activities and membrane topologies.
Hepatitis C
NS3 is a serine protease required for processing of hepatitis C virus polyprotein.
Hepatitis C
NS3 protease inhibitors for treatment of chronic hepatitis C: Efficacy and safety.
Hepatitis C
NS3 protein of Hepatitis C virus associates with the tumour suppressor p53 and inhibits its function in an NS3 sequence-dependent manner.
Hepatitis C
NS3 serine protease of bovine viral diarrhea virus: characterization of active site residues, NS4A cofactor domain, and protease-cofactor interactions.
Hepatitis C
NS3 Variability in Hepatitis C Virus Genotype 1A Isolates from Liver Tissue and Serum Samples of Treatment-Naïve Patients with Chronic Hepatitis C.
Hepatitis C
NS3.4A protease as a target for interfering with hepatitis C virus replication.
Hepatitis C
OCIAD1 is a host mitochondrial substrate of the hepatitis C virus NS3-4A protease.
Hepatitis C
Ombitasvir/paritaprevir/ritonavir + dasabuvir +/- ribavirin in real world hepatitis C patients.
Hepatitis C
Outcomes and Costs of Treating Hepatitis C Patients in the Era of First Generation Protease Inhibitors - Results from the PAN Study.
Hepatitis C
PCR-Based In Vitro Synthesis of Hepatitis C Virus NS3 Protease for Rapid Phenotypic Resistance Testing of Protease Inhibitors.
Hepatitis C
Pegylated interferon based therapy with second-wave direct-acting antivirals in genotype 1 chronic hepatitis C.
Hepatitis C
Peptide-based inhibitors of hepatitis C virus full-length NS3 (protease-helicase/NTPase): model compounds towards small molecule inhibitors.
Hepatitis C
Peptidic inhibitors of the hepatitis C virus serine protease within non-structural protein 3.
Hepatitis C
Peptidomimetic therapeutic agents targeting the protease enzyme of the human immunodeficiency virus and hepatitis C virus.
Hepatitis C
Permeability evaluation of peptidic HCV protease inhibitors in Caco-2 cells-correlation with in vivo absorption predicted in humans.
Hepatitis C
Pharmacodynamic Analysis of a Serine Protease Inhibitor, MK-4519, against Hepatitis C Virus Using a Novel In Vitro Pharmacodynamic System.
Hepatitis C
Pharmacodynamic monitoring of immunosuppressive effects indicates reduced cyclosporine activity during telaprevir therapy.
Hepatitis C
Pharmacodynamics and pharmacokinetics of elbasvir and grazoprevir in the treatment of hepatitis C.
Hepatitis C
Pharmacokinetic and pharmacodynamic interactions between the hepatitis C virus protease inhibitor, boceprevir, and the oral contraceptive ethinyl estradiol/norethindrone.
Hepatitis C
Pharmacokinetic Enhancement in HIV Antiretroviral Therapy: A Comparison of Ritonavir and Cobicistat.
Hepatitis C
Pharmacokinetic enhancement of the hepatitis C virus protease inhibitors VX-950 and SCH 503034 by co-dosing with ritonavir.
Hepatitis C
Pharmacokinetic interactions between telaprevir and antiretroviral drugs in HIV/HCV-coinfected patients with advanced liver fibrosis and prior HCV non-responders.
Hepatitis C
Pharmacokinetic interactions between the hepatitis C virus protease inhibitor boceprevir and ritonavir-boosted HIV-1 protease inhibitors atazanavir, darunavir, and lopinavir.
Hepatitis C
Pharmacokinetic/Pharmacodynamic predictors of clinical potency for hepatitis C virus nonnucleoside polymerase and protease inhibitors.
Hepatitis C
Pharmacokinetics of the co-administration of boceprevir and St John's wort to male and female healthy volunteers.
Hepatitis C
Phase 3 trial of first generation protease inhibitor therapy for hepatitis C virus/human immunodeficiency virus coinfection.
Hepatitis C
Phenotypic and structural analyses of hepatitis C virus NS3 protease Arg155 variants: sensitivity to telaprevir (VX-950) and interferon alpha.
Hepatitis C
Polymorphisms associated with resistance to protease inhibitors in naïve patients infected with hepatitis C virus genotype 1 in Argentina: Low prevalence of Q80K.
Hepatitis C
Polynucleotide modulation of the protease, nucleoside triphosphatase, and helicase activities of a hepatitis C virus NS3-NS4A complex isolated from transfected COS cells.
Hepatitis C
Polypharmacy and Comorbidity Are Associated with a Lower Early Virologic Response in Hepatitis C Patients Treated with First Generation Protease Inhibitor Triple Therapy: A Preliminary Analysis.
Hepatitis C
Population Pharmacokinetic Analysis for Daclatasvir and Asunaprevir in Japanese Subjects With Chronic Hepatitis C Virus Infection.
Hepatitis C
Population Pharmacokinetic Analysis of Daclatasvir, Asunaprevir, and Beclabuvir Combination in HCV-Infected Subjects.
Hepatitis C
Potent Antiviral Activities of the Direct-Acting Antivirals ABT-493 and ABT-530 with Three-Day Monotherapy for Hepatitis C Virus Genotype 1 Infection.
Hepatitis C
Potent inhibition of enterovirus D68 and human rhinoviruses by dipeptidyl aldehydes and ?-ketoamides.
Hepatitis C
Potent novel inhibitors against hepatitis C virus NS3 (HCV NS3 GT-3a) protease domain.
Hepatitis C
Potent peptide inhibitors of human hepatitis C virus NS3 protease are obtained by optimizing the cleavage products.
Hepatitis C
Preclinical characterization of BI 201335, a C-terminal carboxylic acid inhibitor of the hepatitis C virus NS3-NS4A protease.
Hepatitis C
Predicting hepatitis C virus protease cleavage sites using generalized linear indicator regression models.
Hepatitis C
Predictive factors of lopinavir/ritonavir discontinuation for drug-related toxicity: results from a cohort of 416 multi-experienced HIV-infected individuals.
Hepatitis C
Predictors of early treatment discontinuation and severe anemia in a Brazilian cohort of hepatitis C patients treated with first-generation protease inhibitors.
Hepatitis C
Pretransplant and posttransplant treatment of hepatitis C virus infection with protease inhibitors.
Hepatitis C
Pretreatment resistance to hepatitis C virus protease inhibitors boceprevir/telaprevir in hepatitis C virus subgenotype 1a-infected patients from Manitoba.
Hepatitis C
Prevalence of hepatitis C virus mutants resistant to protease inhibitors among Polish HCV genotype 1-infected patients.
Hepatitis C
Prevalence of naturally occurring amino acid substitutions associated with resistance to hepatitis C virus NS3/NS4A protease inhibitors in São Paulo state.
Hepatitis C
Prevalence of naturally occurring protease inhibitor resistance-associated variants in hemodialysis and renal transplant patients with hepatitis C virus infection.
Hepatitis C
Prime site binding inhibitors of a serine protease: NS3/4A of hepatitis C virus.
Hepatitis C
Prisoners treated for hepatitis C with protease inhibitor, New York, USA, 2012.
Hepatitis C
Probing the active site of the hepatitis C virus serine protease by fluorescence resonance energy transfer.
Hepatitis C
Probing the relationship between RNA-stimulated ATPase and helicase activities of HCV NS3 using 2'-O-methyl RNA substrates.
Hepatitis C
Profile of sofosbuvir/velpatasvir/voxilaprevir in the treatment of hepatitis C.
Hepatitis C
Protease and helicase activities of hepatitis C virus genotype 4, 5, and 6 NS3-NS4A proteins.
Hepatitis C
Protease inhibitor therapy post-liver transplantation in the treatment of hepatitis C virus infection.
Hepatitis C
Protease inhibitor-based direct-acting antivirals are associated with increased risk of aminotransferase elevations but not hepatic dysfunction or decompensation.
Hepatitis C
Protease inhibitor-based triple therapy is highly effective for hepatitis C recurrence after liver transplant: a multicenter experience.
Hepatitis C
Protease inhibitor-resistant hepatitis C virus mutants with reduced fitness from impaired production of infectious virus.
Hepatitis C
Protease inhibitors block multiple functions of the NS3/4A protease-helicase during the hepatitis C virus life cycle.
Hepatitis C
Protease inhibitors for the treatment of chronic hepatitis C genotype-1 infection: the new standard of care.
Hepatitis C
Protease inhibitors to treat hepatitis C in the Swiss HIV Cohort Study: high efficacy but low treatment uptake.
Hepatitis C
Protein Tyrosine Phosphatase Nonreceptor Type 2 Expression Does Not Correlate with Viral Load or Response to Direct-Acting Antiviral Therapy in Hepatitis C Virus Infections-Infected Patients.
Hepatitis C
Provisional Guidance on the Use of Hepatitis C Virus Protease Inhibitors for Treatment of Hepatitis C in HIV-Infected Persons.
Hepatitis C
Pseudo-peptides derived from isomannide as potential inhibitors of serine proteases.
Hepatitis C
Randomized controlled trial of danoprevir plus peginterferon alfa-2a and ribavirin in treatment-naïve patients with hepatitis C virus genotype 1 infection.
Hepatitis C
Randomized trial of combined triple therapy comprising two types of peginterferon with simeprevir in patients with HCV genotype 1b.
Hepatitis C
Rapid decline of viral RNA in hepatitis C patients treated with VX-950: a phase Ib, placebo-controlled, randomized study.
Hepatitis C
Rates and Correlates of Incident Type 2 Diabetes Mellitus Among Persons Living With HIV-1 Infection.
Hepatitis C
Rational design of dual-functional aptamers that inhibit the protease and helicase activities of HCV NS3.
Hepatitis C
Re: Pearlman and Ehleben - Hepatitis C Genotype 1 Virus with Low Viral Load and Rapid Virologic Response to Peginterferon/Ribavirin Obviates a Protease Inhibitor.
Hepatitis C
Re: Pearlman and ehleben - hepatitis C genotype 1 virus with low viral load and rapid virologic response to peginterferon/ribavirin obviates a protease inhibitor.
Hepatitis C
Reactivity of the NS2/3(907-1206)ASK(4) protein with beta-mercaptoethanol studied by electrospray ion trap mass spectrometry.
Hepatitis C
Recent advances in hepatitis C virus treatment: review of HCV protease inhibitor clinical trials.
Hepatitis C
Recent developments in the discovery of hepatitis C virus serine protease inhibitors--towards a new class of antiviral agents?
Hepatitis C
Recent progress in the development of selected hepatitis C virus NS3.4A protease and NS5B polymerase inhibitors.
Hepatitis C
Recommendations for the use of hepatitis C virus protease inhibitors for the treatment of chronic hepatitis C in HIV-infected persons. A position paper of the Italian Association for the Study of Infectious and Tropical Disease.
Hepatitis C
Reduced bio-basis function neural networks for protease cleavage site prediction.
Hepatitis C
Regulation of interferon regulatory factor 3-dependent innate immunity by the HCV NS3/4A protease.
Hepatitis C
Regulation of interferon regulatory factor-3 by the hepatitis C virus serine protease.
Hepatitis C
Relation between viral fitness and immune escape within the hepatitis C virus protease.
Hepatitis C
Relative replication capacity and selective advantage profiles of protease inhibitor-resistant hepatitis C virus (HCV) NS3 protease mutants in the HCV genotype 1b replicon system.
Hepatitis C
Renal involvement in hematological disorders: monoclonal immunoglobulins and nephropathy.
Hepatitis C
Resistance analysis of hepatitis C virus genotype 1 prior treatment null responders receiving daclatasvir and asunaprevir.
Hepatitis C
Resistance mutations are rare among protease inhibitor treatment-naive hepatitis C genotype-1 patients with or without HIV coinfection.
Hepatitis C
Resistance of hepatitis C virus to NS3-4A protease inhibitors: mechanisms of drug resistance induced by R155Q, A156T, D168A and D168V mutations.
Hepatitis C
Resistance outside the substrate envelope: hepatitis C NS3/4A protease inhibitors.
Hepatitis C
Resistance profiling of hepatitis C virus protease inhibitors using full-length NS3.
Hepatitis C
Resistance-associated mutations to HCV protease inhibitors naturally pre-existed in HIV/HCV coinfected, treatment-naïve patients.
Hepatitis C
Restoration of the Activated Rig-I Pathway in Hepatitis C Virus (HCV) Replicon Cells by HCV Protease, Polymerase, and NS5A Inhibitors In Vitro at Clinically Relevant Concentrations.
Hepatitis C
Review article: novel antivirals for hepatitis C-sofosbuvir/velpatasvir/voxilaprevir, glecaprevir/pibrentasvir.
Hepatitis C
Ribavirin mode of action in chronic hepatitis C: from clinical use back to molecular mechanisms.
Hepatitis C
Risk and determinants of developing severe liver toxicity during therapy with nevirapine-and efavirenz-containing regimens in HIV-infected patients.
Hepatitis C
Risk factors for sexual and erectile dysfunction in HIV-infected men: the role of protease inhibitors.
Hepatitis C
Risk of Liver Enzyme Elevation during Treatment with Ritonavir-boosted Protease Inhibitors among HIV-monoinfected and HIV/HCV Coinfected Patients.
Hepatitis C
Role of ITPA and SLC28A2 genes in the prediction of anaemia associated with protease inhibitor plus ribavirin and peginterferon in hepatitis C treatment.
Hepatitis C
Role of protease inhibitors and acylation stimulating protein in the adipogenesis in 3T3-L1 cells.
Hepatitis C
Role of viral and host factors in interferon based therapy of hepatitis C virus infection.
Hepatitis C
Roles of the AX(4)GKS and arginine-rich motifs of hepatitis C virus RNA helicase in ATP- and viral RNA-binding activity.
Hepatitis C
Safety and efficacy of faldaprevir in combination with pegylated interferon ?-2b and ribavirin in Japanese patients with genotype-1 chronic hepatitis C virus infection.
Hepatitis C
Safety and Efficacy of Protease Inhibitors to Treat Hepatitis C After Liver Transplantation, a Multicenter Experience.
Hepatitis C
Safety and efficacy of triple therapy with peginterferon, ribavirin and boceprevir within an early access programme in Spanish patients with hepatitis C genotype 1 with severe fibrosis: SVRw12 analysis.
Hepatitis C
SAR and pharmacokinetic studies on phenethylamide inhibitors of the hepatitis C virus NS3/NS4A serine protease.
Hepatitis C
SCH 503034, a novel hepatitis C virus protease inhibitor, plus pegylated interferon alpha-2b for genotype 1 nonresponders.
Hepatitis C
Screening and identification of bioactive compounds from citrus against non-structural protein 3 protease of hepatitis C virus genotype 3a by fluorescence resonance energy transfer assay and mass spectrometry.
Hepatitis C
SCREENING OF PROTEASE INHIBITORS RESISTANCE MUTATIONS IN HEPATITIS C VIRUS ISOLATES INFECTING ROMANIAN PATIENTS UNEXPOSED TO TRIPLE THERAPY.
Hepatitis C
Searching for discrimination rules in protease proteolytic cleavage activity using genetic programming with a min-max scoring function.
Hepatitis C
Selection and characterization of hepatitis C virus replicons dually resistant to the polymerase and protease inhibitors HCV-796 and boceprevir (SCH 503034).
Hepatitis C
Selection of functional variants of the NS3-NS4A protease of hepatitis C virus by using chimeric sindbis viruses.
Hepatitis C
Semliki Forest Virus replicon particles production in serum-free medium BHK-21 cell cultures and their use to express different proteins.
Hepatitis C
Septic Bursitis, a Potential Complication of Protease Inhibitor Use in Hepatitis C Virus.
Hepatitis C
Serine protease of hepatitis C virus expressed in insect cells as the NS3/4A complex.
Hepatitis C
Serpin mechanism of hepatitis C virus nonstructural 3 (NS3) protease inhibition: induced fit as a mechanism for narrow specificity.
Hepatitis C
Short and long-term effects of telaprevir on kidney function in patients with hepatitis C virus infection: a retrospective cohort study.
Hepatitis C
Short-term antiviral efficacy of BILN 2061, a hepatitis C virus serine protease inhibitor, in hepatitis C genotype 1 patients.
Hepatitis C
Significance of monoclonal antibodies against the conserved epitopes within non-structural protein 3 helicase of hepatitis C virus.
Hepatitis C
Simeprevir Potently Suppresses SARS-CoV-2 Replication and Synergizes with Remdesivir.
Hepatitis C
Simeprevir with peginterferon and ribavirin induced interstitial pneumonitis: First case report.
Hepatitis C
Simeprevir With Peginterferon and Ribavirin Leads to High Rates of SVR in Patients With HCV Genotype 1 Who Relapsed After Previous Therapy: A Phase 3 Trial.
Hepatitis C
Simeprevir/pegylated interferon/ribavirin triple therapy for recurrent hepatitis C after living donor liver transplantation.
Hepatitis C
Similarities between Human Immunodeficiency Virus Type 1 and Hepatitis C Virus Genetic and Phenotypic Protease Quasispecies Diversity.
Hepatitis C
Simultaneous assay for protease activities of hepatitis C virus and human immunodeficiency virus based on fluorescence detection.
Hepatitis C
Simultaneous quantification of simeprevir sodium: A hepatitis C protease inhibitor in binary and ternary mixtures with sofosbuvir and/or ledipasvir utilizing direct and H-point standard addition strategies.
Hepatitis C
Single and Multiple Ascending Dose Studies of the NS3 Protease Inhibitor, Asunaprevir, in Subjects With or Without Chronic Hepatitis C.
Hepatitis C
Single strand binding proteins increase the processivity of DNA unwinding by the hepatitis C virus helicase.
Hepatitis C
Single-cell resolution imaging of membrane-anchored hepatitis C virus NS3/4A protease activity.
Hepatitis C
Single-point mutations of hepatitis C virus NS3 that impair p53 interaction and anti-apoptotic activity of NS3.
Hepatitis C
Small molecule degraders of the hepatitis C virus protease reduce susceptibility to resistance mutations.
Hepatitis C
Sofosbuvir in combination with peginterferon alfa-2a and ribavirin for non-cirrhotic, treatment-naive patients with genotypes 1, 2, and 3 hepatitis C infection: a randomised, double-blind, phase 2 trial.
Hepatitis C
Solid phase synthesis of peptide aldehyde protease inhibitors. Probing the proteolytic sites of hepatitis C virus polyprotein.
Hepatitis C
Solution structure and backbone dynamics of an engineered arginine-rich subdomain 2 of the hepatitis C virus NS3 RNA helicase.
Hepatitis C
Specific detection of naturally occurring hepatitis C virus mutants with resistance to telaprevir and boceprevir (protease inhibitors) among treatment-naïve infected individuals.
Hepatitis C
Specificity of the hepatitis C virus NS3 serine protease: effects of substitutions at the 3/4A, 4A/4B, 4B/5A, and 5A/5B cleavage sites on polyprotein processing.
Hepatitis C
StaPLs: versatile genetically encoded modules for engineering drug-inducible proteins.
Hepatitis C
Statin Use Is Associated With Incident Diabetes Mellitus Among Patients in the HIV Outpatient Study.
Hepatitis C
Structural and biological identification of residues on the surface of NS3 helicase required for optimal replication of the hepatitis C virus.
Hepatitis C
Structural characterization of the interactions of optimized product inhibitors with the N-terminal proteinase domain of the hepatitis C virus (HCV) NS3 protein by NMR and modelling studies.
Hepatitis C
Structural determinants for membrane association and dynamic organization of the hepatitis C virus NS3-4A complex.
Hepatitis C
Structural Similarity of SARS-CoV2 Mpro and HCV NS3/4A Proteases Suggests New Approaches for Identifying Existing Drugs Useful as COVID-19 Therapeutics.
Hepatitis C
Structure-activity relationships for the selectivity of hepatitis C virus NS3 protease inhibitors.
Hepatitis C
Studies on the C-terminal of hexapeptide inhibitors of the hepatitis C virus serine protease.
Hepatitis C
Substitutions at NS3 Residue 155, 156, or 168 of Hepatitis C Virus Genotypes 2 to 6 Induce Complex Patterns of Protease Inhibitor Resistance.
Hepatitis C
Successful telaprevir treatment in combination of cyclosporine against recurrence of hepatitis C in the Japanese liver transplant patients.
Hepatitis C
Superinfection and cure of infected cells as mechanisms for hepatitis C virus adaptation and persistence.
Hepatitis C
Suppression of Hepatitis C Virus Genome Replication in Cells with RNA-Cleaving DNA Enzymes and Short-Hairpin RNA.
Hepatitis C
Sustained disappearance of hepatitis C viremia in patients receiving protease inhibitor treatment for human immunodeficiency virus infection.
Hepatitis C
Sustained virologic response after 6 weeks of therapy with a first-generation hepatitis C virus protease inhibitor.
Hepatitis C
Sustained virological response after ten days of triple anti-hepatitis C virus (HCV) therapy with telaprevir plus pegylated interferon and ribavirin in an HIV/HCV co-infected cirrhotic woman.
Hepatitis C
Synergy of a hepatitis C virus (HCV) NS4A antagonist in combination with HCV protease and polymerase inhibitors.
Hepatitis C
Synthetic depsipeptide substrates for the assay of human hepatitis C virus protease.
Hepatitis C
Systematic review: interferon-free regimens for patients with HCV-related Child C cirrhosis.
Hepatitis C
Targeting the non-structural proteins of hepatitis C virus: beyond hepatitis C virus protease and polymerase.
Hepatitis C
Telaprevir is a substrate and moderate inhibitor of P-glycoprotein, a strong inductor of ABCG2, but not an activator of PXR in vitro.
Hepatitis C
Telaprevir or boceprevir based therapy for chronic hepatitis C infection: Development of resistance-associated variants in treatment failure.
Hepatitis C
Telaprevir or boceprevir triple therapy in patients with chronic hepatitis C and varying severity of cirrhosis.
Hepatitis C
Telaprevir: a promising protease inhibitor for the treatment of hepatitis C virus infection.
Hepatitis C
Telaprevir: looking for a sustained virologic response in hepatitis C virus infection.
Hepatitis C
Temporal dynamics of a predominant protease inhibitor-resistance mutation in a treatment-naive, hepatitis C virus-infected individual.
Hepatitis C
Tenofovir use and urinary biomarkers among HIV-infected women in the Women's Interagency HIV Study (WIHS).
Hepatitis C
Tetrapeptides as potent protease inhibitors of Hepatitis C Virus full-length NS3 (protease-helicase/NTPase).
Hepatitis C
THE ABSENCE OF THYROID DISEASE IN AN AUSTRALIAN HEPATITIS C COHORT TREATED WITH TRIPLE COMBINATION THERAPY: A PARADIGM SHIFT.
Hepatitis C
The Acidic Domain of Hepatitis C Virus NS4A Contributes to RNA Replication and Virus Particle Assembly.
Hepatitis C
The acidic sequence of the NS4A cofactor regulates ATP hydrolysis by the HCV NS3 helicase.
Hepatitis C
The antiviral adaptor proteins Cardif and Trif are processed and inactivated by caspases.
Hepatitis C
The arginine-1493 residue in QRRGRTGR1493G motif IV of the hepatitis C virus NS3 helicase domain is essential for NS3 protein methylation by the protein arginine methyltransferase 1.
Hepatitis C
The C terminus of hepatitis C virus NS4A encodes an electrostatic switch that regulates NS5A hyperphosphorylation and viral replication.
Hepatitis C
The Combination of MK-5172, Peginterferon, and Ribavirin is Effective in Treatment-Naive Patients with Hepatitis C Virus Genotype 1 Infection Without Cirrhosis.
Hepatitis C
The design of a potent inhibitor of the hepatitis C virus NS3 protease: BILN 2061--from the NMR tube to the clinic.
Hepatitis C
The effect of the P1 side chain on the binding of optimized carboxylate and activated carbonyl inhibitors of the hepatitis C virus NS3 protease.
Hepatitis C
The efficacy and safety of telaprevir - a new protease inhibitor against hepatitis C virus.
Hepatitis C
The Evaluation of Medication Adherence in Patients Infected With HCV Receiving Protease Inhibitors: A Pilot Study.
Hepatitis C
The hepatitis C virus (HCV) NS4B RNA binding inhibitor clemizole is highly synergistic with HCV protease inhibitors.
Hepatitis C
The hepatitis C virus encodes a serine protease involved in processing of the putative nonstructural proteins from the viral polyprotein precursor.
Hepatitis C
The hepatitis C virus replicon presents a higher barrier to resistance to nucleoside analogs than to nonnucleoside polymerase or protease inhibitors.
Hepatitis C
The interdomain interface in bifunctional enzyme protein 3/4A (NS3/4A) regulates protease and helicase activities.
Hepatitis C
The metal binding site of the hepatitis C virus NS3 protease. A spectroscopic investigation.
Hepatitis C
The molecular and structural basis of advanced antiviral therapy for hepatitis C virus infection.
Hepatitis C
The nonstructural protein 3 protease/helicase requires an intact protease domain to unwind duplex RNA efficiently.
Hepatitis C
The NS3 protein of hepatitis C virus induces caspase-8-mediated apoptosis independent of its protease or helicase activities.
Hepatitis C
The pharmacokinetic evaluation of boceprevir for treatment of Hepatitis C virus.
Hepatitis C
The Pharmacokinetic Interaction Between an Oral Contraceptive Containing Ethinyl Estradiol and Norethindrone and the HCV Protease Inhibitor Telaprevir.
Hepatitis C
The potency-insolubility conundrum in pharmaceuticals: Mechanism and solution for hepatitis C protease inhibitors.
Hepatitis C
The presence of resistance mutations to protease and polymerase inhibitors in Hepatitis C virus sequences from the Los Alamos databank.
Hepatitis C
The protease domain increases the translocation stepping efficiency of the hepatitis C virus NS3-4A helicase.
Hepatitis C
The protease inhibitor, GS-9256, and non-nucleoside polymerase inhibitor tegobuvir alone, with ribavirin, or pegylated interferon plus ribavirin in hepatitis C.
Hepatitis C
The RNA-unwinding activity of hepatitis C virus non-structural protein 3 (NS3) is positively modulated by its protease domain.
Hepatitis C
The Role of Hepatitis C Virus Core Antigen Testing in the Era of Direct Acting Antiviral Therapies: What We Can Learn from the Protease Inhibitors.
Hepatitis C
The Role of IL28B Genotype Testing in the Era of Direct Acting Antiviral Agents.
Hepatitis C
The role of P-glycoprotein in the pharmacokinetics and tissue distribution of a hepatitis C virus protease inhibitor.
Hepatitis C
The role of triple therapy with protease inhibitors in hepatitis C virus genotype 1 naïve patients.
Hepatitis C
The serine protease domain of hepatitis C viral NS3 activates RNA helicase activity by promoting the binding of RNA substrate.
Hepatitis C
The therapeutic approaches for hepatitis C virus: protease inhibitors and polymerase inhibitors.
Hepatitis C
The Ubiquitin-Specific Protease 18 Promotes Hepatitis C Virus Production by Increasing Viral Infectivity.
Hepatitis C
Thermodynamics of zinc binding to hepatitis C virus NS3 protease: A folding by binding event.
Hepatitis C
Towards defining a minimal functional domain for NTPase and RNA helicase activities of the hepatitis C virus NS3 protein.
Hepatitis C
Tracking the evolution of multiple in vitro hepatitis C virus replicon variants under protease inhibitor selection pressure by 454 deep sequencing.
Hepatitis C
Treatment failure and resistance with direct acting antiviral drugs against hepatitis C virus.
Hepatitis C
Treatment of experienced and naïve patients with hepatitis C: focus on telaprevir.
Hepatitis C
Treatment of hepatitis C with an interferon-based lead-in phase: a perspective from mathematical modelling.
Hepatitis C
Treatment of liver transplant recipients who have chronic hepatitis C virus infection.
Hepatitis C
Treatment with protease inhibitors and coinfection with hepatitis C virus are independent predictors of preterm delivery in HIV-infected pregnant women.
Hepatitis C
Trends in hepatitis C virus infection therapy: protease inhibitors a step forward in the era of direct acting antivirals.
Hepatitis C
Trends in Utilization of Statin Therapy and Contraindicated Statin Use in HIV--Infected Adults Treated With Antiretroviral Therapy From 2007 Through 2015.
Hepatitis C
Triple therapy in chronic hepatitis C: initial series in a public health program in the South of Brazil.
Hepatitis C
Triple therapy with first generation HCV protease inhibitors: lead-in or no lead-in phase?
Hepatitis C
Triple Therapy with First Generation Protease Inhibitors for Hepatitis C Markedly Impairs Function of Neutrophil Granulocytes.
Hepatitis C
Triple therapy with first-generation protease inhibitors for patients with genotype 1 chronic hepatitis C: recommendations of the Italian Association for the Study of the Liver (AISF).
Hepatitis C
Two patients treated with pegylated interferon/ribavirin/telaprevir triple therapy for recurrent hepatitis C after living donor liver transplantation.
Hepatitis C
Two Years' Persistence of Naturally Present Substitution R155K Within Hepatitis C Virus NS3 Protease in the Absence of Protease Inhibitor-based Therapy.
Hepatitis C
Two-way interaction study between ritonavirboosted danoprevir, a potent HCV protease inhibitor, and ketoconazole in healthy subjects.
Hepatitis C
Two-Year Follow-Up Analysis of Telaprevir-Based Antiviral Triple Therapy for HCV Recurrence in Genotype 1 Infected Liver Graft Recipients as a First Step towards Modern HCV Therapy.
Hepatitis C
UK consensus guidelines for the use of the protease inhibitors boceprevir and telaprevir in genotype 1 chronic hepatitis C infected patients.
Hepatitis C
Ultra-rapid cardiotoxicity of the hepatitis C virus protease inhibitor BILN 2061 in the urokinase-type plasminogen activator mouse.
Hepatitis C
Understanding the structural and energetic basis of inhibitor and substrate bound to the full-length NS3/4A: insights from molecular dynamics simulation, binding free energy calculation and network analysis.
Hepatitis C
Update on the management and treatment of hepatitis C virus infection: recommendations from the Department of Veterans Affairs Hepatitis C Resource Center Program and the National Hepatitis C Program Office.
Hepatitis C
Use of the fused NS4A peptide-NS3 protease domain to study the importance of the helicase domain for protease inhibitor binding to hepatitis C virus NS3-NS4A.
Hepatitis C
Using pharmacokinetic and viral kinetic modeling to estimate the antiviral effectiveness of telaprevir, boceprevir, and pegylated interferon during triple therapy in treatment-experienced hepatitis C virus-infected cirrhotic patients.
Hepatitis C
Vaniprevir plus peginterferon alfa-2a and ribavirin in treatment-experienced Japanese patients with hepatitis C virus genotype 1 infection: a randomized phase II study.
Hepatitis C
Vaniprevir plus peginterferon alfa-2b and ribavirin in treatment-experienced Japanese patients with hepatitis C virus genotype 1 (GT1b) infection: phase 3 studies.
Hepatitis C
Variability and resistance mutations in the hepatitis C virus NS3 protease in patients not treated with protease inhibitors.
Hepatitis C
Viral hepatitis and liver transplantation: pathogenesis, prevention and therapy of recurrent disease.
Hepatitis C
Viral kinetics in patients with chronic hepatitis C treated with the serine protease inhibitor BILN 2061.
Hepatitis C
Withdrawal: Hepatitis C virus NS5A and subgenomic replicon activate NF- ? B via tyrosine phosphorylation of I ? B ? and its degradation by calpain protease.
Hepatitis C
Yeast Endoplasmic Reticulum Sequestration Screening for the Engineering of Proteases from Libraries Expressed in Yeast.
Hepatitis C
[Analysis of the causes leading to withdrawal of the treatment with triple antiviral therapy for hepatitis C patients].
Hepatitis C
[Boceprevir: new possibilities for antiviral treatment of chronic hepatitis C].
Hepatitis C
[Characteristics in treatment organization of chronic hepatitis in Hungary: Hepatitis Registry and Priority Index].
Hepatitis C
[Clarifying the crystal structure of hepatitis C virus NS3/NS4A protease complex--basics for the development of specific HCV protease inhibitors?]
Hepatitis C
[Determination of the naturally occurring Q80K mutation in the HCV NS3 protease gene].
Hepatitis C
[Experience in the management of immunosuppressant treatment with hepatitis C virus protease inhibitors.]
Hepatitis C
[Hepatitis C virus NS3/4A with different secondary structures at amino-terminus has different serine protease activities and inhibitory activities on host cell]
Hepatitis C
[Immunogenetic factors of interaction of hepatitis C virus and human and possibilities of development of therapeutic tactic].
Hepatitis C
[Management of side effects induced by antiviral therapy for chronic hepatitis infection].
Hepatitis C
[Selection and characterization of peptides that specifically binding to hepatitis C virus serine protease]
Hepatitis C
[Significance of hepatitis C virus baseline polymorphism during the antiviral therapy].
Hepatitis C
[The combined application of nucleotide and amino acid sequences of NS3 hepatitis C virus protein, DNA encoding granulocyte macrophage colony-stimulating factor and inhibitor of regulatory T cells induces effective immune response against hepatitis C virus].
Hepatitis C
[Therapy spectrum in hepatitis C extended. Newer NS3/4A protease inhibitor in chronic hepatitis C-GT1/4 infection].
Hepatitis C
[What is expected from the novel triple combination antiviral treatment of patients infected with hepatitis C virus genotype 1?].
Hepatitis C, Chronic
A cost utility analysis of simeprevir used with peginterferon?+?ribavirin in the management of genotype 1 hepatitis C virus infection, from the perspective of the UK National Health Service.
Hepatitis C, Chronic
A network meta-analysis to compare simeprevir with boceprevir and telaprevir in combination with peginterferon-? and ribavirin in patients infected with genotype 1 Hepatitis C virus.
Hepatitis C, Chronic
A practical guide for the use of boceprevir and telaprevir for the treatment of hepatitis C.
Hepatitis C, Chronic
A randomized trial of daclatasvir with peginterferon alfa-2b and ribavirin for HCV genotype 1 infection.
Hepatitis C, Chronic
Advances in the Diagnosis and Monitoring of Hepatitis C Virus Infection.
Hepatitis C, Chronic
Antiretroviral therapy based on protease inhibitors as a protective factor against liver fibrosis progression in patients with chronic hepatitis C.
Hepatitis C, Chronic
Aplastic Anemia and Severe Myelosuppression with Boceprevir or Simeprevir-Containing Hepatitis C Virus Treatment.
Hepatitis C, Chronic
Approach to the treatment-naïve patient with HCV genotype 1 infection.
Hepatitis C, Chronic
Binding and inhibitory effect of ravidasvir on 3CLpro of SARS-CoV-2: a molecular docking, molecular dynamics and MM/PBSA approach.
Hepatitis C, Chronic
Boceprevir in genotype 1 chronic hepatitis C: first experiences in Serbia.
Hepatitis C, Chronic
Boceprevir: a novel nonstructural 3 (NS3) protease inhibitor for the treatment of chronic hepatitis C infection.
Hepatitis C, Chronic
Boceprevir: A Protease Inhibitor for the Treatment of Chronic Hepatitis C (September).
Hepatitis C, Chronic
Characterizing the Pharmacokinetic Interaction Between Simeprevir and Odalasvir in Healthy Volunteers Using a Population Modeling Approach.
Hepatitis C, Chronic
Chronic hepatitis C: treat or wait? A prospective study on reasons for treatment or nontreatment in the era of first-generation protease inhibitors.
Hepatitis C, Chronic
Clinical significance of residual viremia detected by two real-time PCR assays for response-guided therapy of HCV genotype 1 infection.
Hepatitis C, Chronic
Clinical Significance of Two Real-Time PCR Assays for Chronic Hepatitis C Patients Receiving Protease Inhibitor-Based Therapy.
Hepatitis C, Chronic
Controlled-release interferon alpha 2b, a new member of the interferon family for the treatment of chronic hepatitis C.
Hepatitis C, Chronic
Correction: Neutrophil and Monocyte Function in Patients with Chronic Hepatitis C Undergoing Antiviral Therapy with Regimens Containing Protease Inhibitors with and without Interferon.
Hepatitis C, Chronic
Cost-effectiveness analysis is a mandatory strategy for health systems: evidence from a study involving therapies for hepatitis C.
Hepatitis C, Chronic
Cost-effectiveness analysis of boceprevir for the treatment of chronic hepatitis C virus genotype 1 infection in Portugal.
Hepatitis C, Chronic
Cost-effectiveness analysis of simeprevir in combination with peginterferon and ribavirin for treatment-naïve chronic hepatitis C genotype 1 patients in Japan.
Hepatitis C, Chronic
Cost-effectiveness of boceprevir in patients previously treated for chronic hepatitis C genotype 1 infection in the United States.
Hepatitis C, Chronic
Cost-effectiveness of protease inhibitor based regimens for chronic hepatitis C: a systematic review of published literature.
Hepatitis C, Chronic
Dermatologic adverse events of protease inhibitor-based combination therapy in patients with chronic hepatitis C.
Hepatitis C, Chronic
Detection of low HCV viraemia by repeated HCV RNA testing predicts treatment failure to triple therapy with telaprevir.
Hepatitis C, Chronic
Direct costs of first-generation protease inhibitors for the treatment of genotype 1 chronic hepatitis C viral infection.
Hepatitis C, Chronic
Direct-Acting Antiviral-Associated Dermatitis During Chronic Hepatitis C Virus Treatment.
Hepatitis C, Chronic
Does antiviral therapy reduce the risk of hepatocellular carcinoma in patients with chronic hepatitis C?
Hepatitis C, Chronic
Drug-drug interactions in the treatment of HCV among people who inject drugs.
Hepatitis C, Chronic
Drug-Induced Liver Injury: Highlights from a Review of the 2015 Literature.
Hepatitis C, Chronic
Dynamic and rapid changes in viral quasispecies by UDPS in chronic hepatitis C patients receiving telaprevir-based therapy.
Hepatitis C, Chronic
Effect of native vitamin D3 supplementation on refractory chronic hepatitis C patients in simeprevir with pegylated interferon/ribavirin.
Hepatitis C, Chronic
Effect of telaprevir on the metabolism and hepatic uptake of tacrolimus (FK506).
Hepatitis C, Chronic
Efficacy and safety of telaprevir, a new protease inhibitor, for difficult-to-treat patients with genotype 1 chronic hepatitis C.
Hepatitis C, Chronic
Efficacy and safety profile of boceprevir- or telaprevir-based triple therapy or dual peginterferon alfa-2a or alfa-2b plus ribavirin therapy in chronic hepatitis C: the real-world PegBase observational study.
Hepatitis C, Chronic
Efficacy of the regimen using twice-daily ?-interferon followed by the standard of care for chronic hepatitis C genotype 1b with high viral load.
Hepatitis C, Chronic
Elbasvir/Grazoprevir: A Review of the Latest Agent in the Fight against Hepatitis C.
Hepatitis C, Chronic
Evolutionary Pathways to Persistence of Highly Fit and Resistant Hepatitis C Virus Protease Inhibitor Escape Variants.
Hepatitis C, Chronic
First clinical study using HCV protease inhibitor danoprevir to treat COVID-19 patients.
Hepatitis C, Chronic
First-wave protease inhibitors for hepatitis C genotype 1 treatment: a real-life experience in Brazilian patients.
Hepatitis C, Chronic
Formulary management of the protease inhibitors boceprevir and telaprevir for chronic hepatitis C virus.
Hepatitis C, Chronic
Fosamprenavir treatment in a highly active antiretroviral therapy schedule induces a HCV-RNA decrease and a Th1 network boost in HIV/HCV-coinfected patients.
Hepatitis C, Chronic
Futility of antiviral treatments for hepatitis C: An evolving concept entering the direct antiviral agents era.
Hepatitis C, Chronic
Glecaprevir/pibrentasvir for the treatment of chronic hepatitis C virus infection in adults.
Hepatitis C, Chronic
Glomerular filtration rate change during chronic hepatitis C treatment with Sofosbuvir/Ledipasvir in HCV/HIV Coinfected patients treated with Tenofovir and a boosted protease inhibitor: an observational prospective study.
Hepatitis C, Chronic
Grazoprevir, Elbasvir, and Ribavirin for Chronic Hepatitis C Virus Genotype 1 Infection After Failure of Pegylated Interferon and Ribavirin With an Earlier-Generation Protease Inhibitor: Final 24-Week Results From C-SALVAGE.
Hepatitis C, Chronic
HCV genotype 1-6 NS3 residue 80 substitutions impact protease inhibitor activity and promote viral escape.
Hepatitis C, Chronic
Hepatic Decompensation Likely Attributable to Simeprevir in Patients with Advanced Cirrhosis.
Hepatitis C, Chronic
Hepatitis C in Brazil: lessons learned with boceprevir and telaprevir.
Hepatitis C, Chronic
Hepatitis C treatment with triple therapy in a patient with hemophilia A.
Hepatitis C, Chronic
How to optimize HCV therapy in genotype 1 patients: management of side-effects.
Hepatitis C, Chronic
How to optimize HCV therapy in genotype 1 patients: predictors of response.
Hepatitis C, Chronic
IFN-? gene polymorphisms as predictive factors in chronic hepatitis C treatment-naive patients without access to protease inhibitors.
Hepatitis C, Chronic
IL28B polymorphism is not associated with HCV protease diversity in patients co-infected with HIV and HCV treated with pegylated interferon and ribavirin.
Hepatitis C, Chronic
Impact of HCV protease-inhibitor-based triple therapy for chronic HCV genotype 1 infection.
Hepatitis C, Chronic
IMPACT OF THE PEGYLATED-INTERFERON AND RIBAVIRIN THERAPY ON THE TREATMENT-RELATED MORTALITY OF PATIENTS WITH CIRRHOSIS DUE TO HEPATITIS C VIRUS.
Hepatitis C, Chronic
Induction of interleukin-6 by interferon alfa and its abrogation by a serine protease inhibitor in patients with chronic hepatitis C.
Hepatitis C, Chronic
Inflammatory markers neopterin and alanine aminotransferase in HCV patients treated with HCV NS3.4A protease inhibitor telaprevir (VX-950) and/or peginterferon alfa-2a.
Hepatitis C, Chronic
Interferon-based combination treatment for chronic hepatitis C in the era of direct acting antivirals.
Hepatitis C, Chronic
Lack of drug interaction between cyclosporine and telaprevir in a liver transplant recipient.
Hepatitis C, Chronic
Limited effectiveness and safety profile of protease inhibitor-based triple therapy against chronic hepatitis C in a real-world cohort with a high proportion of advanced liver disease.
Hepatitis C, Chronic
Low Pretreatment Acoustic Radiation Force Impulse Imaging (ARFI) Values Predict Sustained Virological Response in Antiviral Hepatitis C Virus (HCV) Therapy.
Hepatitis C, Chronic
Low SVR rates in clinical practice for treating genotype 1 chronic hepatitis C with protease inhibitors boceprevir and telaprevir.
Hepatitis C, Chronic
Medical resource utilization and costs among Australian patients with genotype 1 chronic hepatitis C: results of a retrospective observational study.
Hepatitis C, Chronic
Mericitabine and Either Boceprevir or Telaprevir in Combination with Peginterferon Alfa-2a plus Ribavirin for Patients with Chronic Hepatitis C Genotype 1 Infection and Prior Null Response: The Randomized DYNAMO 1 and DYNAMO 2 Studies.
Hepatitis C, Chronic
Mouse Systems to Model Hepatitis C Virus Treatment and Associated Resistance.
Hepatitis C, Chronic
Nationwide experience of treatment with protease inhibitors in chronic hepatitis C patients in denmark: identification of viral resistance mutations.
Hepatitis C, Chronic
Nationwide prediction of future expenditure for protease inhibitors in chronic hepatitis C.
Hepatitis C, Chronic
Naturally occurring hepatitis C virus protease inhibitors resistance-associated mutations among chronic hepatitis C genotype 1b patients with or without HIV co-infection.
Hepatitis C, Chronic
Network meta-analysis of first- and second-generation protease inhibitors for chronic hepatitis C genotype 1: efficacy based on RVR and SVR 24.
Hepatitis C, Chronic
Neutrophil and Monocyte Function in Patients with Chronic Hepatitis C Undergoing Antiviral Therapy with Regimens Containing Protease Inhibitors with and without Interferon.
Hepatitis C, Chronic
New protease inhibitors for the treatment of chronic hepatitis C: a cost-effectiveness analysis.
Hepatitis C, Chronic
New triple therapy for chronic hepatitis C: real life clinical experience in a community setting.
Hepatitis C, Chronic
Predictors of early treatment discontinuation and severe anemia in a Brazilian cohort of hepatitis C patients treated with first-generation protease inhibitors.
Hepatitis C, Chronic
Protease inhibitor-based direct-acting antivirals are associated with increased risk of aminotransferase elevations but not hepatic dysfunction or decompensation.
Hepatitis C, Chronic
Protease inhibitor-based triple therapy in chronic hepatitis C: Guidelines by the French association for the study of the Liver.
Hepatitis C, Chronic
Protease Inhibitors Drug Resistance Mutations in Turkish Patients with Chronic Hepatitis C.
Hepatitis C, Chronic
Protease inhibitors for the treatment of chronic hepatitis C genotype-1 infection: the new standard of care.
Hepatitis C, Chronic
Protease inhibitors partially overcome the interferon nonresponse phenotype in patients with chronic hepatitis C.
Hepatitis C, Chronic
Protease inhibitors-based therapy induces acquired spherocytic-like anaemia and ineffective erythropoiesis in chronic hepatitis C virus patients.
Hepatitis C, Chronic
Protease inhibitors: Silver bullets for chronic hepatitis C infection?
Hepatitis C, Chronic
Provisional Guidance on the Use of Hepatitis C Virus Protease Inhibitors for Treatment of Hepatitis C in HIV-Infected Persons.
Hepatitis C, Chronic
Rapid decline of viral RNA in chronic hepatitis C patients treated once daily with IDX320: a novel macrocyclic HCV protease inhibitor.
Hepatitis C, Chronic
Recent successes and noteworthy future prospects in the treatment of chronic hepatitis C.
Hepatitis C, Chronic
Recommendations for the use of hepatitis C virus protease inhibitors for the treatment of chronic hepatitis C in HIV-infected persons. A position paper of the Italian Association for the Study of Infectious and Tropical Disease.
Hepatitis C, Chronic
Relative efficacy and safety of simeprevir and telaprevir in treatment-naïve hepatitis C-infected patients in a Japanese population: A Bayesian network meta-analysis.
Hepatitis C, Chronic
Renal impairment in patients with chronic hepatitis C treated with first generation protease inhibitors.
Hepatitis C, Chronic
Resistance-associated variants in chronic hepatitis C patients treated with protease inhibitors.
Hepatitis C, Chronic
Ribavirin mode of action in chronic hepatitis C: from clinical use back to molecular mechanisms.
Hepatitis C, Chronic
Ritonavir-boosted protease inhibitor based therapy: a new strategy in chronic hepatitis C therapy.
Hepatitis C, Chronic
Safety and Efficacy of Partial Splenic Embolization in Telaprevir-based Triple Therapy for Chronic Hepatitis C.
Hepatitis C, Chronic
Safety and efficacy of protease inhibitor based combination therapy in a single-center "real-life" cohort of 110 patients with chronic hepatitis C genotype 1 infection.
Hepatitis C, Chronic
Safety aspects of protease inhibitors for chronic hepatitis C: Adverse events and drug-to-drug interactions.
Hepatitis C, Chronic
Short article: Faldaprevir, deleobuvir and ribavirin in IL28B non-CC patients with HCV genotype-1a infection included in the SOUND-C3 phase 2b study.
Hepatitis C, Chronic
Simeprevir increases rate of sustained virologic response among treatment-experienced patients with HCV genotype-1 infection: a phase IIb trial.
Hepatitis C, Chronic
Single and Multiple Ascending Dose Studies of the NS3 Protease Inhibitor, Asunaprevir, in Subjects With or Without Chronic Hepatitis C.
Hepatitis C, Chronic
Successful retreatment with 12 weeks of glecaprevir and pibrentasvir for a genotype 2a HCV-infected hemodialysis patient who failed to respond to 8 weeks of prior glecaprevir and pibrentasvir therapy.
Hepatitis C, Chronic
Sustained virological response after ten days of triple anti-hepatitis C virus (HCV) therapy with telaprevir plus pegylated interferon and ribavirin in an HIV/HCV co-infected cirrhotic woman.
Hepatitis C, Chronic
Telaprevir versus boceprevir in chronic hepatitis C: a meta-analysis of data from phase II and III trials.
Hepatitis C, Chronic
Telaprevir-Induced Renal Adverse Events in Japanese Patients Reported in the PMDA Adverse Drug Reactions Reporting Database.
Hepatitis C, Chronic
THE ABSENCE OF THYROID DISEASE IN AN AUSTRALIAN HEPATITIS C COHORT TREATED WITH TRIPLE COMBINATION THERAPY: A PARADIGM SHIFT.
Hepatitis C, Chronic
The changing face of hepatitis C in the new era of direct-acting antivirals.
Hepatitis C, Chronic
The Journey to the Discovery of Boceprevir: an NS3-NS4 HCV protease inhibitor for the treatment of chronic hepatitis C.
Hepatitis C, Chronic
The presence of resistance mutations to protease and polymerase inhibitors in Hepatitis C virus sequences from the Los Alamos databank.
Hepatitis C, Chronic
Therapeutic algorithms for chronic hepatitis C in the DAA era during the current economic crisis: whom to treat? How to treat? When to treat?
Hepatitis C, Chronic
Treatment of chronic hepatitis C complicated by mixed cryoglobulinemia with new protease inhibitor, sofosbuvir.
Hepatitis C, Chronic
Treatment of chronic hepatitis C with protease inhibitor-based therapy after liver transplantation.
Hepatitis C, Chronic
Treatment of chronic hepatitis C: anticipated impact of resistance in patients treated with protease inhibitors.
Hepatitis C, Chronic
Treatment of experienced and naïve patients with hepatitis C: focus on telaprevir.
Hepatitis C, Chronic
Treatment strategies for chronic hepatitis C: update since the 1997 National Institutes of Health Consensus Development Conference.
Hepatitis C, Chronic
Treatment with daclatasvir and sofosbuvir for 24 weeks without ribavirin in cirrhotic patients who failed first-generation protease inhibitors.
Hepatitis C, Chronic
Triple combination treatment for chronic hepatitis C with protease inhibitors, pegylated interferon and ribavirin: 'lead-in or no lead-in'?
Hepatitis C, Chronic
Triple therapy with first-generation protease inhibitors for patients with genotype 1 chronic hepatitis C: recommendations of the Italian Association for the Study of the Liver (AISF).
Hepatitis C, Chronic
UK consensus guidelines for the use of the protease inhibitors boceprevir and telaprevir in genotype 1 chronic hepatitis C infected patients.
Hepatitis C, Chronic
Ultradeep pyrosequencing of NS3 to predict response to triple therapy with protease inhibitors in previously treated chronic hepatitis C patients.
Hepatitis C, Chronic
Ultrasound evaluation of perihepatic lymph nodes during antiviral therapy with the protease inhibitor telaprevir (VX-950) in patients with chronic hepatitis C infection.
Hepatitis C, Chronic
Update of the Belgian Association for the Study of the Liver guidelines for the treatment of chronic hepatitis C genotype 1 with protease inhibitors.
Hepatitis C, Chronic
USP18 downregulation in peripheral blood mononuclear cells predicts nonresponse to interferon-based triple therapy in patients with chronic hepatitis C, genotype 1: a pilot study.
Hepatitis C, Chronic
Viral kinetics in patients with chronic hepatitis C treated with the serine protease inhibitor BILN 2061.
Hepatitis C, Chronic
Vitamin D-related gene polymorphisms do not influence the outcome and serum vitamin D level in pegylated interferon/ribavirin therapy combined with protease inhibitor for patients with genotype 1b chronic hepatitis C.
Hepatitis C, Chronic
[Boceprevir and telaprevir utilization: evaluation for the treatment of chronic hepatitis C].
Hepatitis C, Chronic
[CLINICAL AND ECONOMIC ANALYSIS OF ALTERNATIVE SCHEMES OF ANTIVIRAL THERAPY OF CHRONIC HEPATITIS C GENOTYPE 1 IN PATIENTS WHO DID NOT ANSWER TO THE PRIOR THERAPY, IN THE RUSSIAN FEDERATION].
Hepatitis C, Chronic
[Efficacy and safety of a protease inhibitor with pegylated interferon and ribavirin in patients with untreated chronic hepatitis C: a meta analysis].
Hepatitis C, Chronic
[Expert opinion on boceprevir- and telaprevir-based triple therapies of chronic hepatitis C].
Hepatitis C, Chronic
[Future prospects for hepatitis C treatment: Without interferon and ribavirin?]
Hepatitis C, Chronic
[Molecular mechanisms of hepatitis C virus (HCV) replication - implications for the development of antiviral drugs].
Hepatitis C, Chronic
[National Consensus Document by GESIDA/National Aids Plan on Antiretroviral Treatment in Adults Infected by the Human Immunodeficiency Virus (January 2011 Update).]
Hepatitis C, Chronic
[New era in the treatment of chronic hepatitis C - novel direct acting antivirals].
Hepatitis C, Chronic
[Resistance to protease inhibitors and efficiency of antiviral therapy in patients with chronic hepatitis C].
Hepatitis C, Chronic
[Side-effects of pegylated interferon plus ribavirin therapy with or without protease inhibitor direct acting antiviral agents during treatment of chronic hepatitis C virus infection].
Hepatitis C, Chronic
[Systematic review of new protease inhibitors interactions: telaprevir and boceprevir].
Hepatitis C, Chronic
[Treatment of chronic hepatitis C with protease inhibitors: dawn of a new era].
Hepatitis E
Hepatitis E virus ORF1 encoded non structural protein-host protein interaction network.
Hepatitis E
The 41-amino-acid C-terminal region of the hepatitis E virus ORF3 protein interacts with bikunin, a kunitz-type serine protease inhibitor.
Hepatitis, Chronic
Deep sequencing and phylogenetic analysis of variants resistant to interferon-based protease inhibitor therapy in chronic hepatitis induced by genotype 1b hepatitis C virus.
Hepatitis, Chronic
Efficient inhibition of human leukocytic elastase by means of ?1 -antitrypsin/peptide complexes.
Hepatitis, Chronic
Evidence for the presence of an inactive precursor of human hepatocyte growth factor in plasma and sera of patients with liver diseases.
Hepatitis, Chronic
Hepatotoxicity and antiretroviral therapy with protease inhibitors: A review.
Hepatitis, Chronic
Protease inhibitors for treatment of chronic hepatitis C--a new target for the magic bullet identified.
Hepatitis, Chronic
Raltegravir, tenofovir, and emtricitabine in an HIV-infected patient with HCV chronic hepatitis, NNRTI intolerance and protease inhibitors-induced severe liver toxicity.
Hepatitis, Chronic
The design of a potent inhibitor of the hepatitis C virus NS3 protease: BILN 2061--from the NMR tube to the clinic.
Hepatitis, Chronic
[Resistance to protease inhibitors and efficiency of antiviral therapy in patients with chronic hepatitis C].
Hepatitis, Chronic
[Therapy spectrum in hepatitis C extended. Newer NS3/4A protease inhibitor in chronic hepatitis C-GT1/4 infection].
Hepatoblastoma
[Prokaryotic expression, purification and activity analysis of recombinant human serine protease inhibitor Hespintor Kazal Domain].
Hereditary Angioedema Type III
Defective glycosylation of coagulation factor XII underlies hereditary angioedema type III.
Heredodegenerative Disorders, Nervous System
Residual levels of tripeptidyl-peptidase I activity dramatically ameliorate disease in late-infantile neuronal ceroid lipofuscinosis.
Heredodegenerative Disorders, Nervous System
The human CLN2 protein/tripeptidyl-peptidase I is a serine protease that autoactivates at acidic pH.
Hernias, Diaphragmatic, Congenital
Rare and de novo variants in 827 congenital diaphragmatic hernia probands implicate LONP1 as candidate risk gene.
Herpes Simplex
A facile system for construction of HSV-1 variants: site directed mutation of the UL26 protease gene in HSV-1.
Herpes Simplex
A herpesvirus ubiquitin-specific protease is critical for efficient T cell lymphoma formation.
Herpes Simplex
Alterations in catalytic activity and virus maturation produced by mutation of the conserved histidine residues of herpes simplex virus type 1 protease.
Herpes Simplex
Autocatalytic Activity of the Ubiquitin-Specific Protease Domain of Herpes Simplex Virus 1 VP1-2.
Herpes Simplex
Autoproteolysis of herpes simplex virus type 1 protease releases an active catalytic domain found in intermediate capsid particles.
Herpes Simplex
Characterization of Novel Piperidine-Based Inhibitor of Cathepsin B-Dependent Bacterial Toxins and Viruses.
Herpes Simplex
Characterization of the protease and other products of amino-terminus-proximal cleavage of the herpes simplex virus 1 UL26 protein.
Herpes Simplex
Cloning, expression, and immunogenicity of the assembly protein of varicella-zoster virus and detection of the products of open reading frame 33.
Herpes Simplex
Conformational change in the herpes simplex single-strand binding protein induced by DNA.
Herpes Simplex
Differentiation of multiple domains in the herpes simplex virus 1 protease encoded by the UL26 gene.
Herpes Simplex
Evidence for controlled incorporation of herpes simplex virus type 1 UL26 protease into capsids.
Herpes Simplex
Expression and analysis of the human cytomegalovirus UL80-encoded protease: identification of autoproteolytic sites.
Herpes Simplex
Expression of natural and synthetic genes encoding herpes simplex virus 1 protease in Escherichia coli and purification of the protein.
Herpes Simplex
Functional interaction between the ESCRT-I component TSG101 and the HSV-1 tegument ubiquitin specific protease.
Herpes Simplex
Herpes Simplex Virus 1 Serine Protease VP24 Blocks the DNA-Sensing Signal Pathway by Abrogating Activation of Interferon Regulatory Factor 3.
Herpes Simplex
Herpes Simplex Virus 1 Ubiquitin-Specific Protease UL36 Abrogates NF-?B Activation in DNA Sensing Signal Pathway.
Herpes Simplex
Herpes Simplex Virus 1 Ubiquitin-Specific Protease UL36 Inhibits Beta Interferon Production by Deubiquitinating TRAF3.
Herpes Simplex
Herpes Simplex Virus 1 UL36USP Antagonizes Type I Interferon-Mediated Antiviral Innate Immunity.
Herpes Simplex
Herpes simplex virus downregulates secretory leukocyte protease inhibitor: a novel immune evasion mechanism.
Herpes Simplex
Herpes simplex virus downregulation of secretory leukocyte protease inhibitor enhances human papillomavirus type 16 infection.
Herpes Simplex
Herpes simplex virus type 1 protease expressed in Escherichia coli exhibits autoprocessing and specific cleavage of the ICP35 assembly protein.
Herpes Simplex
Identification and characterization of an extracellular protease activity produced by the marine Vibrio sp. 60.
Herpes Simplex
Identification of a minimal hydrophobic domain in the herpes simplex virus type 1 scaffolding protein which is required for interaction with the major capsid protein.
Herpes Simplex
Identification of the herpes simplex virus-1 protease cleavage sites by direct sequence analysis of autoproteolytic cleavage products.
Herpes Simplex
Identification of the serine residue at the active site of the herpes simplex virus type 1 protease.
Herpes Simplex
Impact of the Interaction between Herpes Simplex Virus Type 1 Regulatory Protein ICP0 and Ubiquitin-Specific Protease USP7 on Activation of Adeno-Associated Virus Type 2 rep Gene Expression.
Herpes Simplex
Improved purification protocol of the HSV-1 protease catalytic domain, using immunoaffinity.
Herpes Simplex
In vitro activity of the herpes simplex virus type 1 protease with peptide substrates.
Herpes Simplex
Investigation of the specificity of the herpes simplex virus type 1 protease by point mutagenesis of the autoproteolysis sites.
Herpes Simplex
Limited proteolysis of herpes simplex virus glycoproteins that occurs during their extraction from vero cells.
Herpes Simplex
Mistranslational errors associated with the rare arginine codon CGG in Escherichia coli.
Herpes Simplex
Na, an autoproteolytic product of the herpes simplex virus type 1 protease, can functionally substitute for the assembly protein ICP35.
Herpes Simplex
Nucleotide sequence of the herpes simplex virus type 2 gene encoding the protease and capsid protein ICP35.
Herpes Simplex
Phenotype of the herpes simplex virus type 1 protease substrate ICP35 mutant virus.
Herpes Simplex
Production of recombinant herpes simplex virus protease in 10-L stirred vessels using a baculovirus-insect cell expression system.
Herpes Simplex
Protease inhibitors suppress fibrinolytic activity of herpesvirus-transformed cells.
Herpes Simplex
Protease pretreatment increases the efficacy of adenovirus-mediated gene therapy for the treatment of an experimental glioblastoma model.
Herpes Simplex
Protein profiling with Epstein-Barr nuclear antigen-1 reveals an interaction with the herpesvirus-associated ubiquitin-specific protease HAUSP/USP7.
Herpes Simplex
Proteolytic cleavage of bovine herpesvirus 1 (BHV-1) glycoprotein gB is not necessary for its function in BHV-1 or pseudorabies virus.
Herpes Simplex
Purification of active herpes simplex virus-1 protease expressed in Escherichia coli.
Herpes Simplex
Reciprocal activities between herpes simplex virus type 1 regulatory protein ICP0, a ubiquitin E3 ligase, and ubiquitin-specific protease USP7.
Herpes Simplex
Recombinant full-length human cytomegalovirus protease has lower activity than recombinant processed protease domain in purified enzyme and cell-based assays.
Herpes Simplex
Release of the catalytic domain N(o) from the herpes simplex virus type 1 protease is required for viral growth.
Herpes Simplex
Release of the herpes simplex virus 1 protease by self cleavage is required for proper conformation of the portal vertex.
Herpes Simplex
Retraction. Tsg101 interacts with herpes simplex virus 1 VP1/2 and is a substrate of VP1/2 ubiquitin-specific protease domain activity.
Herpes Simplex
Separate functional domains of the herpes simplex virus type 1 protease: evidence for cleavage inside capsids.
Herpes Simplex
Stimulation of the herpes simplex virus type I protease by antichaeotrophic salts.
Herpes Simplex
Targeted gene therapy of the HSV-TK/hIL-12 fusion gene controlled by the hSLPI gene promoter of human non-small cell lung cancer in vitro.
Herpes Simplex
The ability of herpes simplex virus type 1 immediate-early protein Vmw110 to bind to a ubiquitin-specific protease contributes to its roles in the activation of gene expression and stimulation of virus replication.
Herpes Simplex
The C-terminal 25 amino acids of the protease and its substrate ICP35 of herpes simplex virus type 1 are involved in the formation of sealed capsids.
Herpes Simplex
The Challenge of Potential Drug-Drug Interactions Among People Living With HIV on Antiretroviral Therapy: A Cross-Sectional Study in Selected Provinces in China.
Herpes Simplex
The herpes simplex virus 1 gene encoding a protease also contains within its coding domain the gene encoding the more abundant substrate.
Herpes Simplex
The major transcriptional regulatory protein of herpes simplex virus type 1 includes a protease resistant DNA binding domain.
Herpes Simplex
The protease of herpes simplex virus type 1 is essential for functional capsid formation and viral growth.
Herpes Simplex
Tissue factor and glycoprotein C on herpes simplex virus type 1 are protease activated receptor 2 cofactors that enhance infection.
Herpes Simplex
Towards the application of Tc toxins as a universal protein translocation system.
Herpes Simplex
Tsg101 interacts with herpes simplex virus 1 VP1/2 and is a substrate of VP1/2 ubiquitin-specific protease domain activity.
Herpes Simplex
Ubiquitin-specific protease 9X in host cells interacts with herpes simplex virus 1 ICP0.
Herpes Zoster
61 diploid (bos taurus) and tetraploid (bos indicus) embryo aggregation to produce bovine embryonic chimeras.
Herpes Zoster
79 THE CELL-CYCLE RELATED NUCLEAR LOCALIZATION OF PLATELET-ACTIVATING FACTOR IN BOVINE AND MURINE EMBRYO DEVELOPMENT.
Herpes Zoster
A mouse serine protease TESP5 is selectively included into lipid rafts of sperm membrane presumably as a glycosylphosphatidylinositol-anchored protein.
Herpes Zoster
A survey of the effects of proteases and glycosidases on culture of rabbit morulae to blastocysts.
Herpes Zoster
Acrosin accelerates the dispersal of sperm acrosomal proteins during acrosome reaction.
Herpes Zoster
Acrosin is essential for sperm penetration through the zona pellucida in hamsters.
Herpes Zoster
Activation and penetration in vitro of pig oocytes treated with calcium ionophore.
Herpes Zoster
Alterations in mast cell proteinases and protease inhibitors in the progress of cutaneous herpes zoster infection.
Herpes Zoster
Association of high fetuin-B concentrations in serum with fertilization rate in IVF: a cross-sectional pilot study.
Herpes Zoster
Biophysical properties of the zona pellucida measured by capillary suction: is zona hardening a mechanical phenomenon?
Herpes Zoster
Changes in composition of the porcine zona pellucida during development of the oocyte to the 2- to 4-cell embryo.
Herpes Zoster
Difference of acrosomal serine protease system between mouse and other rodent sperm.
Herpes Zoster
Effector sites in the three-dimensional structure of mammalian sperm beta-acrosin.
Herpes Zoster
Effects of protease inhibitors on adenylate cyclase activation and aldosterone production in rat adrenal zona glomerulosa cells.
Herpes Zoster
Effects of the oviduct and wheat germ agglutinin on enzymatic digestion of porcine zona pellucidae.
Herpes Zoster
Evidence for the involvement of a species-specific embryonic protease in zona escape of hamster blastocysts.
Herpes Zoster
Fetuin inhibits zona pellucida hardening and conversion of ZP2 to ZP2f during spontaneous mouse oocyte maturation in vitro in the absence of serum.
Herpes Zoster
Herpes zoster as an immune restoration disease in AIDS patients during therapy including protease inhibitors.
Herpes Zoster
High incidence of herpes zoster in patients with AIDS soon after therapy with protease inhibitors.
Herpes Zoster
Intactness of zona pellucida does not affect the secretion of a trypsin-like protease from mouse blastocyst.
Herpes Zoster
Kallikrein-6-Regulated Pathways Shed Light on New Potential Targets in Varicella Zoster Virus Infection.
Herpes Zoster
Liver condition of Holstein cows affects mitochondrial function and fertilization ability of oocytes.
Herpes Zoster
Ovastacin, a cortical granule protease, cleaves ZP2 in the zona pellucida to prevent polyspermy.
Herpes Zoster
Oviductal estrogen receptor ? signaling prevents protease-mediated embryo death.
Herpes Zoster
Predictive factors of herpes zoster HIV-infected patients: another adverse effect of crack cocaine.
Herpes Zoster
Protease activity involvement in the passage of mammalian sperm through the zona pellucida.
Herpes Zoster
Rates and Correlates of Incident Type 2 Diabetes Mellitus Among Persons Living With HIV-1 Infection.
Herpes Zoster
Recombinant fetuin-B protein maintains high fertilization rate in cumulus cell-free mouse oocytes.
Herpes Zoster
Sarcoidosis-related anterior uveitis in a patient with human immunodeficiency virus.
Herpes Zoster
Site-directed mutagenesis of rabbit proacrosin. Identification of residues involved in zona pellucida binding.
Herpes Zoster
Spermadhesins of the AQN and AWN families, DQH sperm surface protein and HNK protein in the heparin-binding fraction of boar seminal plasma.
Herpes Zoster
Structural characterization of fish egg vitelline envelope proteins by mass spectrometry.
Herpes Zoster
Studies on in vitro proteolytic sensitivity of peptides inhibiting herpes simplex virus ribonucleotide reductases lead to discovery of a stable and potent inhibitor.
Herpes Zoster
Testase 1 (ADAM 24) a plasma membrane-anchored sperm protease implicated in sperm function during epididymal maturation or fertilization.
Herpes Zoster
The C-terminal region of OVGP1 remodels the zona pellucida and modifies fertility parameters.
Herpes Zoster
The histochemical localization of acrosin in guinea-pig sperm after the acrosome reaction.
Herpes Zoster
The serine protease hepsin mediates urinary secretion and polymerisation of Zona Pellucida domain protein uromodulin.
Herpes Zoster
The serine protease testisin is present on the surface of capacitated stallion spermatozoa and interacts with key zona pellucida binding proteins.
Herpes Zoster
The structures of the bovine and porcine proacrosin genes and their conservation among mammals.
Herpes Zoster
Timing of oviductal fluid collection, steroid concentrations, and sperm preservation method affect porcine in vitro fertilization efficiency.
Herpes Zoster
Ultrastructural changes in hatching-gland cells of pike embryos (Esox lucius L.) and evidence for their degeneration by apoptosis.
Hidradenitis Suppurativa
Impaired Notch-MKP-1 signalling in hidradenitis suppurativa: an approach to pathogenesis by evidence from translational biology.
Hirschsprung Disease
Effects of potato-derived protease inhibitors on perianal dermatitis after colon resection for long-segment Hirschsprung's disease.
Hirschsprung Disease
Increased protease activated receptors in the colon of patients with Hirschsprung's disease.
Histoplasmosis
Protease inhibitors and azolic antifungals in HIV patients with histoplasmosis: a clinical pharmacokinetics perspective.
HIV Enteropathy
Plasma citrulline is a biomarker of enterocyte mass and an indicator of parenteral nutrition in HIV-infected patients.
HIV Infections
A bivalent recombinant protein inactivates HIV-1 by targeting the gp41 prehairpin fusion intermediate induced by CD4 D1D2 domains.
HIV Infections
A combination of nucleoside analogues and a protease inhibitor reduces HIV-1 RNA levels in semen: implications for sexual transmission of HIV infection.
HIV Infections
A correlation analysis of HHV infection and its predictive factors in an HIV-seropositive population in Yunnan, China.
HIV Infections
A cross-sectional study to evaluate the association of hyperbilirubinaemia on markers of cardiovascular disease, neurocognitive function, bone mineral density and renal markers in HIV-1 infected subjects on protease inhibitors.
HIV Infections
A first case of protease codon 35 amino acid insertion in a HIV-1 subtype B sequence detected in the Bauru region, state of São Paulo, Brazil: case report.
HIV Infections
A generalized seizure following initiation of nelfinavir in a patient with human immunodeficiency virus type 1 infection, suspected due to interaction between nelfinavir and phenytoin.
HIV Infections
A phase I/II study of the protease inhibitor indinavir in children with HIV infection.
HIV Infections
A population analysis of weight-related differences in lopinavir pharmacokinetics and possible consequences for protease inhibitor-naive and -experienced patients.
HIV Infections
A preliminary evaluation of nelfinavir mesylate, an inhibitor of human immunodeficiency virus (HIV)-1 protease, to treat HIV infection.
HIV Infections
A randomized controlled trial of a protease inhibitor (saquinavir) in combination with zidovudine in previously untreated patients with advanced HIV infection.
HIV Infections
A structural basis for the acute effects of HIV protease inhibitors on GLUT4 intrinsic activity.
HIV Infections
Abacavir compared to protease inhibitors as part of HAART regimens for treatment of HIV infection: patient satisfaction and implications for adherence.
HIV Infections
Abacavir sulfate/lamivudine/zidovudine fixed combination in the treatment of HIV infection.
HIV Infections
Abacavir/lamividune combination in the treatment of HIV-1 infection: a review.
HIV Infections
Abnormalities in apolipoprotein and lipid levels in an HIV-infected Brazilian population under different treatment profiles: the relevance of apolipoprotein E genotypes and immunological status.
HIV Infections
Abnormalities in plasma fatty acid composition in human immunodeficiency virus-infected children treated with protease inhibitors.
HIV Infections
Acute pancreatitis in HIV-infected patients: are etiologies changing since the introduction of protease inhibitor therapy?
HIV Infections
Adherence to protease inhibitor therapy and outcomes in patients with HIV infection.
HIV Infections
Advanced liver fibrosis in HIV/HCV-coinfected patients on antiretroviral therapy.
HIV Infections
Adverse cutaneous reactions associated with the newest antiretroviral drugs in patients with human immunodeficiency virus infection.
HIV Infections
Altered fat distribution in HIV-positive men on nucleoside analog reverse transcriptase inhibitor therapy.
HIV Infections
Alveolar echinococcosis of the liver in an adult with human immunodeficiency virus type-1 infection.
HIV Infections
Amprenavir-induced maculopapular exanthem followed by desensitization in a patient with late-stage human immunodeficiency virus.
HIV Infections
Amprenavir: a review of its clinical potential in patients with HIV infection.
HIV Infections
An Increased Risk of Osteoporosis during Acquired Immunodeficiency Syndrome.
HIV Infections
An inhibitor of the protease blocks maturation of human and simian immunodeficiency viruses and spread of infection.
HIV Infections
An open-label, prospective, observational study of the incidence of coronary artery disease in patients with HIV infection receiving highly active antiretroviral therapy.
HIV Infections
Annexin A2 antibodies but not inhibitors of the annexin A2 heterotetramer impair productive HIV-1 infection of macrophages in vitro.
HIV Infections
Anti-tat hutat2:Fc mediated protection against tat-induced neurotoxicity and HIV-1 replication in human monocyte-derived macrophages.
HIV Infections
Antiretroviral Drug Guidelines for the Treatment of HIV Infection: Should Protease Inhibitors Always be Included in the Initial Regimen or Not?
HIV Infections
Antiretroviral Protease Inhibitors Accelerate Glutathione Export from Viable Cultured Rat Neurons.
HIV Infections
Antiretroviral treatment in pediatric HIV infection in the United States: from clinical trials to clinical practice.
HIV Infections
Antiretroviral treatment reduces very-low-density lipoprotein and intermediate-density lipoprotein apolipoprotein B fractional catabolic rate in human immunodeficiency virus-infected patients with mild dyslipidemia.
HIV Infections
Antiviral profile of HIV inhibitors in macrophages: implications for therapy.
HIV Infections
Apoptosis induced by HIV infection in H9 T cells is blocked by ICE-family protease inhibition but not by a Fas(CD95) antagonist.
HIV Infections
Applications of Click Chemistry in the Development of HIV Protease Inhibitors.
HIV Infections
Aspartic protease inhibitors containing tertiary alcohol transition-state mimics.
HIV Infections
Assessment of atherosclerosis using carotid ultrasonography in a cohort of HIV-positive patients treated with protease inhibitors.
HIV Infections
Association Between the Framingham Risk Score and Carotid Artery Intima-Media Thickness in Patients With Human Immunodeficiency Virus.
HIV Infections
Association of HIV viral load with monocyte chemoattractant protein-1 and atherosclerosis burden measured by magnetic resonance imaging.
HIV Infections
Atazanavir for treatment of HIV infection in clinical routine: efficacy, pharmacokinetics and safety.
HIV Infections
Bile pigments as HIV-1 protease inhibitors and their effects on HIV-1 viral maturation and infectivity in vitro.
HIV Infections
Bioelectrical impedance analysis in HIV-infected patients treated with triple antiretroviral treatment.
HIV Infections
Body weight changes with protease inhibitor treatment in undernourished HIV-infected patients.
HIV Infections
Brain delivery of transferrin coupled indinavir submicron lipid emulsions--pharmacokinetics and tissue distribution.
HIV Infections
Cardiovascular considerations in patients treated with HIV protease inhibitors.
HIV Infections
Carotid artery intima-media thickness and HIV infection: traditional risk factors overshadow impact of protease inhibitor exposure.
HIV Infections
Carotid artery thickness is associated with chronic use of highly active antiretroviral therapy in patients infected with human immunodeficiency virus: A 3.0 Tesla magnetic resonance imaging study.
HIV Infections
Carpal tunnel syndrome in HIV-infected patients treated with highly active antiretroviral therapy: other case reports.
HIV Infections
Carrier rate of zidovudine-resistant HIV-1: the impact of failing therapy on transmission of resistant strains.
HIV Infections
Cathepsin G, a neutrophil-derived serine protease, increases susceptibility of macrophages to acute human immunodeficiency virus type 1 infection.
HIV Infections
Central nervous system penetration and effectiveness of darunavir/ritonavir monotherapy.
HIV Infections
Cervicovaginal levels of lactoferrin, secretory leukocyte protease inhibitor, and RANTES and the effects of coexisting vaginoses in human immunodeficiency virus (HIV)-seronegative women with a high risk of heterosexual acquisition of HIV infection.
HIV Infections
Challenges in providing comprehensive and coordinated care to HIV/AIDS patients: a Canadian perspective.
HIV Infections
Changes in CD4 lymphocyte counts after interruption of therapy in patients with viral failure on protease inhibitor-containing regimens. Royal Free Centre for HIV Medicine.
HIV Infections
Changes in circulation of B and non-B HIV strains: spotlight on a reference centre for infectious diseases in Northern Italy.
HIV Infections
Circulating levels and ex vivo production of beta-chemokines, interferon gamma, and interleukin 2 in advanced human immunodeficiency virus type 1 infection: the effect of protease inhibitor therapy.
HIV Infections
Circulating metabolites of the human immunodeficiency virus protease inhibitor nelfinavir in humans: structural identification, levels in plasma, and antiviral activities.
HIV Infections
Clinical pharmacokinetics of nelfinavir combined with efavirenz and stavudine during rescue treatment of heavily pretreated HIV-infected patients.
HIV Infections
Clinical, virologic, and immunologic response to efavirenz-or protease inhibitor-based highly active antiretroviral therapy in a cohort of antiretroviral-naive patients with advanced HIV infection (EfaVIP 2 study).
HIV Infections
Combination antiretroviral therapy improves psychomotor speed performance in HIV-seropositive homosexual men. Multicenter AIDS Cohort Study (MACS).
HIV Infections
Combined effect of zidovudine (ZDV), lamivudine (3TC) and abacavir (ABC) antiretroviral therapy in suppressing in vitro FIV replication.
HIV Infections
Combined radiation sensitizing and anti-angiogenic effects of ionizing radiation and the protease inhibitor ritonavir in a head and neck carcinoma model.
HIV Infections
Comparative CD4 T-cell responses of reverse transcriptase inhibitor therapy with or without nelfinavir matched for viral exposure.
HIV Infections
Computer simulations of slow progression of human immunodeficiency virus infection and relapse during anti-HIV treatment with reverse transcriptase inhibitors and protease inhibitors.
HIV Infections
Conformational landscape of non-B variants of HIV-1 protease: A pulsed EPR study.
HIV Infections
Core-shell nanoparticles for targeted and combination antiretroviral activity in gut-homing T cells.
HIV Infections
Correlation between self-reported adherence to highly active antiretroviral therapy (HAART) and virologic outcome.
HIV Infections
Cost-Effectiveness of Three Alternative Boosted Protease Inhibitor-Based Second-Line Regimens in HIV-Infected Patients in West and Central Africa.
HIV Infections
Current status and future prospects of therapeutic drug monitoring and applied clinical pharmacology in antiretroviral therapy.
HIV Infections
Current treatment strategies, complications and considerations for the use of HIV antiretroviral therapy during pregnancy.
HIV Infections
Darunavir : a nonpeptidic protease inhibitor for antiretroviral-naive and treatment-experienced adults with HIV infection.
HIV Infections
Declines in low birth weight and preterm birth among infants who were born to HIV-infected women during an era of increased use of maternal antiretroviral drugs: Pediatric Spectrum of HIV Disease, 1989-2004.
HIV Infections
Deep sequencing of HIV-1 variants from paired plasma and cerebrospinal fluid during primary HIV infection.
HIV Infections
Detection of free and immune-complexed serine protease and its antibody in TB patients with and without HIV co-infection.
HIV Infections
Determination of 19 antiretroviral agents in pharmaceuticals or suspected products with two methods using high-performance liquid chromatography.
HIV Infections
Developing HIV-1 Protease Inhibitors through Stereospecific Reactions in Protein Crystals.
HIV Infections
Development of inhibitors of reverse transcriptase and protease as therapeutics against HIV infection.
HIV Infections
Development of resistance of human immunodeficiency virus (HIV) to anti-HIV agents: how to prevent the problem?
HIV Infections
Diagnosis, prevention, and treatment of bone fragility in people living with HIV: a position statement from the Swiss Association against Osteoporosis.
HIV Infections
Different origin of adipogenic stem cells influences the response to antiretroviral drugs.
HIV Infections
Differential Body Composition Effects of Protease Inhibitors Recommended for Initial Treatment of HIV Infection: A Randomized Clinical Trial.
HIV Infections
Diminished representation of HIV-1 variants containing select drug resistance-conferring mutations in primary HIV-1 infection.
HIV Infections
Discovery and Development of anti-HIV Therapeutic Agents: Progress Towards Improved HIV Medication.
HIV Infections
Disease progression, adherence, and response to protease inhibitor therapy for HIV infection in an Urban Veterans Affairs Medical Center.
HIV Infections
Dolutegravir plus lamivudine dual therapy - a new option for initial antiretroviral therapy.
HIV Infections
Drug monitoring of pyrimethamine during maintenance therapy of toxoplasmic encephalitis in patients with advanced HIV infection during HAART.
HIV Infections
Drugs in traditional drug classes (nucleoside reverse transcriptase inhibitor/nonnucleoside reverse transcriptase inhibitor/protease inhibitors) with activity against drug-resistant virus (tipranavir, darunavir, etravirine).
HIV Infections
Dyslipidaemia in HIV-1-infected patients receiving protease inhibitors after initial treatment with first-line-based non-nucleoside reverse transcriptase inhibitors: a cross-sectional study.
HIV Infections
Early antiviral treatment in outpatients with COVID-19 (FLARE): a structured summary of a study protocol for a randomised controlled trial.
HIV Infections
Early combination treatment with existing HIV antivirals: an effective treatment for COVID-19?
HIV Infections
Effect of exercise on cardiac and metabolic outcomes in people living with HIV.
HIV Infections
Effect of hyperbilirubinaemia on neurocognitive, renal, bone and cardiovascular markers in HIV infection treated with boosted protease inhibitors.
HIV Infections
Effect of protease therapy on cytokine secretion by peripheral blood mononuclear cells (PBMC) from HIV-infected subjects.
HIV Infections
Effect of ritonavir on the pharmacokinetics of the benzimidazoles albendazole and mebendazole: an interaction study in healthy volunteers.
HIV Infections
Effect of two different combinations of antiretrovirals (AZT+ddI and AZT+3TC) on cytokine production and apoptosis in asymptomatic HIV infection.
HIV Infections
Effectiveness of first-generation HCV protease inhibitors: does HIV coinfection still play a role?
HIV Infections
Effects of antiretroviral therapy on tube-like network formation of human endothelial cells.
HIV Infections
Effects of rosuvastatin versus pravastatin on low-density lipoprotein diameter in HIV-1-infected patients receiving ritonavir-boosted protease inhibitor.
HIV Infections
Effects of the H(2)-Receptor Antagonist Famotidine on the Pharmacokinetics of Atazanavir-Ritonavir With or Without Tenofovir in HIV-Infected Patients.
HIV Infections
Efficacy and safety of darunavir-ritonavir compared with that of lopinavir-ritonavir at 48 weeks in treatment-experienced, HIV-infected patients in TITAN: a randomised controlled phase III trial.
HIV Infections
Efficacy of single-tablet darunavir, cobicistat, emtricitabine, and tenofovir alafenamide in the treatment of HIV-1.
HIV Infections
Efficacy of the CCR5 antagonist maraviroc in reducing early, ritonavir-induced atherogenesis and advanced plaque progression in mice.
HIV Infections
Efficacy, safety, and adherence with a twice-daily combination lamivudine/zidovudine tablet formulation, plus a protease inhibitor, in HIV infection.
HIV Infections
Elevated Plasma Ceramides Are Associated With Antiretroviral Therapy Use and Progression of Carotid Artery Atherosclerosis in HIV Infection.
HIV Infections
Elevated plasma concentrations of protease inhibitors and nonnucleoside reverse transcriptase inhibitors in patients coinfected with human immunodeficiency virus and hepatitis B or C: case series and literature review.
HIV Infections
Enhancement of cellular uptake, transport and oral absorption of protease inhibitor saquinavir by nanocrystal formulation.
HIV Infections
Evaluation of simplified protease inhibitor dosing regimens for the treatment of HIV infection.
HIV Infections
Evaluation of the virological and metabolic effects of switching protease inhibitor combination antiretroviral therapy to nevirapine-based therapy for the treatment of HIV infection.
HIV Infections
Exploring the potency of currently used drugs against HIV-1 protease of subtype D variant by using multiscale simulations.
HIV Infections
Extravirologic modulation of immune response by an NRTI-sparing antiretroviral regimen including darunavir and maraviroc.
HIV Infections
Factors associated with collagen deposition in lymphoid tissue in long-term treated HIV-infected patients.
HIV Infections
Fibrates or statins and lipid plasma levels in 245 patients treated with highly active antiretroviral therapy. Aquitaine Cohort, France, 1999-2001.
HIV Infections
Fixed dose darunavir boosted with cobicistat combined with emtricitabine and tenofovir alafenamide fumarate.
HIV Infections
Four Amino Acid Changes in HIV-2 Protease Confer Class-Wide Sensitivity to Protease Inhibitors.
HIV Infections
Hepatitis C and HIV Co-Infection: New Drugs in Practice and in the Pipeline.
HIV Infections
Hepatitis C is associated with type 2 diabetes mellitus in HIV-infected persons without traditional risk factors.
HIV Infections
Hepatitis C virus genetic variability in 52 human immunodeficiency virus-coinfected patients.
HIV Infections
Highly active antiretroviral therapy: pharmacoeconomic issues in the management of HIV infection.
HIV Infections
HIV drug resistance surveillance for prioritizing treatment in resource-limited settings.
HIV Infections
HIV infection and protease genetic diversity in a rural area of the Southern Central African Republic.
HIV Infections
HIV protease inhibitor ritonavir induces renal fibrosis and dysfunction: role of platelet-derived TGF-?1 and intervention via anti-oxidant pathways.
HIV Infections
HIV protease inhibitors: advances in therapy and adverse reactions, including metabolic complications.
HIV Infections
HIV-1 upregulates Fas ligand expression in CD4+ T cells in vitro and in vivo: association with Fas-mediated apoptosis and modulation by aurintricarboxylic acid.
HIV Infections
HIV-1-Tat modulates the function of monocytes and alters their interactions with microvessel endothelial cells. A mechanism of HIV pathogenesis.
HIV Infections
Human immunodeficiency virus type 1 protease inhibitor modulates activation of peripheral blood CD4(+) T cells and decreases their susceptibility to apoptosis in vitro and in vivo.
HIV Infections
Hyperlipidaemia a risk factor for femoral head osteonecrosis (Legg-Calv -Perthes-like disease) in children with AIDS: case report.
HIV Infections
Hyperlipidemia and insulin resistance are induced by protease inhibitors independent of changes in body composition in patients with HIV infection.
HIV Infections
Iatrogenic Cushing syndrome and multifocal osteonecrosis caused by the interaction between inhaled fluticasone and ritonavir.
HIV Infections
Identification of inhibitors of the HIV-1 gp41 six-helix bundle formation from extracts of Chinese medicinal herbs Prunella vulgaris and Rhizoma cibotte.
HIV Infections
Impact of drug resistance mutations on virologic response to salvage therapy. Swiss HIV Cohort Study.
HIV Infections
Impact of PI and NNRTI HAART-based therapy on oral lesions of Brazilian HIV-infected patients.
HIV Infections
Impact of protease inhibitor therapy on HIV-related oropharyngeal candidiasis.
HIV Infections
Impact of protease inhibitors on AIDS-defining events and hospitalizations in 10 French AIDS reference centres. Fédération National des Centres de Lutte contre le SIDA.
HIV Infections
Impaired infectivity of ritonavir-resistant HIV is rescued by heat shock protein 90AB1.
HIV Infections
Improving non-nucleoside reverse transcriptase inhibitors for first-line treatment of HIV infection: the development pipeline and recent clinical data.
HIV Infections
Increased expression of secretory leukocyte protease inhibitor -SLPI- in oral mucosa of Colombian HIV-1-exposed seronegative individuals.
HIV Infections
Increased PAI-1 and tPA antigen levels are reduced with metformin therapy in HIV-infected patients with fat redistribution and insulin resistance.
HIV Infections
Increased prevalence of the alpha-1-antitrypsin (A1AT) deficiency-related S gene in patients infected with human immunodeficiency virus type 1.
HIV Infections
Increased use of lipid-lowering therapy in patients receiving human immunodeficiency virus protease inhibitors.
HIV Infections
Influence of drug transport proteins on the pharmacokinetics and drug interactions of HIV protease inhibitors.
HIV Infections
Influence of pravastatin on carotid artery structure and function in dyslipidemic HIV-infected patients receiving antiretroviral therapy.
HIV Infections
Inhibition Profiling of Retroviral Protease Inhibitors Using an HIV-2 Modular System.
HIV Infections
Initial viral decay to assess the relative antiretroviral potency of protease inhibitor-sparing, nonnucleoside reverse transcriptase inhibitor-sparing, and nucleoside reverse transcriptase inhibitor-sparing regimens for first-line therapy of HIV infection.
HIV Infections
Interaction of anti-HIV protease inhibitors with the multidrug transporter P-glycoprotein (P-gp) in human cultured cells.
HIV Infections
Interleukin-1 beta converting enzyme-like protease involvement in Fas-induced and activation-induced peripheral blood T cell apoptosis in HIV infection. TNF-related apoptosis-inducing ligand can mediate activation-induced T cell death in HIV infection.
HIV Infections
Intracellular antiviral activity of low-dose ritonavir in boosted protease inhibitor regimens.
HIV Infections
Intracellular interactions between nucleos(t)ide inhibitors of HIV reverse transcriptase.
HIV Infections
Intracellular phosphorylation of zidovudine (ZDV) and other nucleoside reverse transcriptase inhibitors (RTI) used for human immunodeficiency virus (HIV) infection.
HIV Infections
Is the atherosclerotic process accentuated under conditions of HIV infection, antiretroviral therapy, and protease inhibitor exposure? Meta-analysis of the markers of arterial structure and function.
HIV Infections
Knocking out human immunodeficiency virus through non-nucleoside reverse transcriptase inhibitors used as single agents or in combinations: a paradigm for the cure of AIDS?
HIV Infections
Lack of impact of protease inhibitor resistance-associated mutations on the outcome of HIV-1-infected patients switching to darunavir-based dual therapy.
HIV Infections
Lipid-lowering efficacy and safety after switching to atazanavir-ritonavir-based highly active antiretroviral therapy in patients with human immunodeficiency virus.
HIV Infections
Liver damage underlying unexplained transaminase elevation in human immunodeficiency virus-1 mono-infected patients on antiretroviral therapy.
HIV Infections
LMNA mutations induce a non-inflammatory fibrosis and a brown fat-like dystrophy of enlarged cervical adipose tissue.
HIV Infections
Long-term clinical benefit after highly active antiretroviral therapy in advanced HIV-1 infection, even in patients without immune reconstitution.
HIV Infections
Long-term efficacy, safety, and tolerability of indinavir-based therapy in protease inhibitor-naive adults with advanced HIV infection.
HIV Infections
Lopinavir plus ritonavir: a novel protease inhibitor combination for HIV infections.
HIV Infections
Lopinavir/Ritonavir, an Antiretroviral Drug, Lowers Sperm Quality and Induces Testicular Oxidative Damage in Rats.
HIV Infections
Lopinavir/Ritonavir: A Review of Analytical Methodologies for the Drug Substances, Pharmaceutical Formulations and Biological Matrices.
HIV Infections
Loss to Followup in HIV-Infected Patients from Asia-Pacific Region: Results from TAHOD.
HIV Infections
Low interleukin-10 production is associated with diabetes in HIV-infected patients undergoing antiviral therapy.
HIV Infections
Macrophages and HIV infection: therapeutical approaches toward this strategic virus reservoir.
HIV Infections
Management of dyslipidaemia in HIV-infected patients receiving antiretroviral therapy.
HIV Infections
Mechanisms for the deterioration in glucose tolerance associated with HIV protease inhibitor regimens.
HIV Infections
Metabolic Abnormalities Associated with the Use of Protease Inhibitors and Non-nucleoside Reverse Transcriptase Inhibitors.
HIV Infections
Metabolism-mediated drug interactions associated with ritonavir-boosted tipranavir in mice.
HIV Infections
Micronised fenofibrate: an updated review of its clinical efficacy in the management of dyslipidaemia.
HIV Infections
Model-based approach for optimization of atazanavir dose recommendations for HIV-infected pediatric patients.
HIV Infections
Molecular mechanisms of HIV protease inhibitor-induced endothelial dysfunction.
HIV Infections
Mucosal and systemic fungal infections in patients with AIDS: prophylaxis and treatment.
HIV Infections
Mucosal Serpin A1 and A3 Levels in HIV Highly Exposed Sero-Negative Women are Affected by the Menstrual Cycle and Hormonal Contraceptives but are Independent of Epidemiological Confounders.
HIV Infections
Multi-Step Inhibition against HIV Lifecycle-Underlying the "Magic" of Protease Inhibitors.
HIV Infections
Multiple Molecular Dynamics Simulations of the Inhibitor GRL-02031 Complex with Wild Type and Mutant HIV-1 Protease Reveal the Binding and Drug-Resistance Mechanism.
HIV Infections
Natural history of HIV infection in the era of combination antiretroviral therapy.
HIV Infections
Neurodevelopmental functioning in HIV-infected infants and young children before and after the introduction of protease inhibitor-based highly active antiretroviral therapy.
HIV Infections
Neurodevelopmental/neuroradiologic recovery of a child infected with HIV after treatment with combination antiretroviral therapy using the HIV-specific protease inhibitor ritonavir.
HIV Infections
Neuropharmacokinetic evaluation of lactoferrin-treated indinavir-loaded nanoemulsions: remarkable brain delivery enhancement.
HIV Infections
No evidence for proliferation in the blood CD4+ T-cell pool during HIV-1 infection and triple combination therapy.
HIV Infections
Nonnucleoside Reverse-transcriptase Inhibitor- vs Ritonavir-boosted Protease Inhibitor-based Regimens for Initial Treatment of HIV Infection: A Systematic Review and Metaanalysis of Randomized Trials.
HIV Infections
Novel Central Nervous System (CNS)-Targeting Protease Inhibitors for Drug-Resistant HIV Infection and HIV-Associated CNS Complications.
HIV Infections
Novel compounds in preclinical/early clinical development for the treatment of HIV infections.
HIV Infections
Optimized antiretroviral therapy: the role of therapeutic drug monitoring and pharmacogenomics.
HIV Infections
Oropharyngeal candidiasis in HIV-infected patients under treatment with protease inhibitors.
HIV Infections
Overcoming resistance to existing therapies in HIV-infected patients: the role of new antiretroviral drugs.
HIV Infections
Pharmacokinetic enhancement of inhibitors of the human immunodeficiency virus protease by coadministration with ritonavir.
HIV Infections
Pharmacokinetics and Virological Efficacy after Switch to Once-Daily Lopinavir-Ritonavir in Treatment-Experienced HIV-1-Infected Children.
HIV Infections
Physiologically Based Pharmacokinetic Modeling for Predicting the Effect of Intrinsic and Extrinsic Factors on Darunavir or Lopinavir Exposure Coadministered With Ritonavir.
HIV Infections
Pilot study evaluating the interaction between paclitaxel and protease inhibitors in patients with human immunodeficiency virus-associated Kaposi's sarcoma: an Eastern Cooperative Oncology Group (ECOG) and AIDS Malignancy Consortium (AMC) trial.
HIV Infections
Plasma bile acid concentrations in patients with human immunodeficiency virus infection receiving protease inhibitor therapy: possible implications for hepatotoxicity.
HIV Infections
Polymorphisms in p1-p6/p6* of HIV type 1 can delay protease autoprocessing and increase drug susceptibility.
HIV Infections
Population trends in the prevalence and patterns of protease resistance related to exposure to unboosted and boosted protease inhibitors.
HIV Infections
Positive and sustained effects of highly active antiretroviral therapy on HIV-1-associated neurocognitive impairment.
HIV Infections
Post-exercise heart rate recovery in HIV-positive individuals on highly active antiretroviral therapy. Early indicator of cardiovascular disease?
HIV Infections
Prevalence of and Risk Factors for Prediabetes in Patients Infected With HIV.
HIV Infections
Prevalence of genotypic resistance to nucleoside analogues and protease inhibitors in antiretroviral-naive HIV patients in Campania, Italy.
HIV Infections
Prevalence of metabolic syndrome in HIV-infected patients naive to antiretroviral therapy or receiving a first-line treatment.
HIV Infections
Profile of darunavir in the treatment of HIV-infected pediatric and adolescent patients.
HIV Infections
Progression of atherosclerosis as assessed by carotid intima-media thickness in patients with HIV infection.
HIV Infections
Prospective evaluation of the effect of initiating indinavir-based therapy on insulin sensitivity and B-cell function in HIV-infected patients.
HIV Infections
Protease inhibitor combination therapy, severity of illness, and quality of life among children with perinatally acquired HIV-1 infection.
HIV Infections
Protease inhibitor monotherapy as maintenance regimen in patients with HIV infection.
HIV Infections
Protease inhibitor monotherapy for long-term management of HIV infection: a randomised, controlled, open-label, non-inferiority trial.
HIV Infections
Protease inhibitor therapy for HIV infection: the effect on HIV-associated nephrotic syndrome.
HIV Infections
Protease inhibitor therapy improves protein catabolism in prepubertal children with HIV infection.
HIV Infections
Protease inhibitor therapy in children with perinatally acquired HIV infection.
HIV Infections
Protease inhibitor-associated hyperglycemia in Mexican patients with HIV infection.
HIV Infections
Protease inhibitor-based antiretroviral therapy in treatment-naive HIV-1-infected patients: the evidence behind the options.
HIV Infections
Protease inhibitor-based therapy is associated with decreased HIV-related health care costs in men treated at a Veterans Administration hospital.
HIV Infections
Protease Inhibitors and Renal Function in Patients with HIV Infection: a Systematic Review.
HIV Infections
Protease inhibitors in HIV infection. Lipodystrophy may be a consequence of prolonged survival.
HIV Infections
Rate of accumulation of thymidine analogue mutations in patients continuing to receive virologically failing regimens containing zidovudine or stavudine: implications for antiretroviral therapy programs in resource-limited settings.
HIV Infections
Rationale and experience with reverse transcriptase inhibitors and protease inhibitors.
HIV Infections
Recent patents and emerging therapeutics for HIV infections: a focus on protease inhibitors.
HIV Infections
Regression of HIV-associated progressive encephalopathy of childhood during HAART.
HIV Infections
Relationship between efficacy, tolerance, and plasma drug concentration of ritonavir in children with advanced HIV infection.
HIV Infections
Repurposing Saquinavir for Host-Directed Therapy to Control Mycobacterium Tuberculosis Infection.
HIV Infections
Resistance mutations are rare among protease inhibitor treatment-naive hepatitis C genotype-1 patients with or without HIV coinfection.
HIV Infections
Response to newly prescribed lipid-lowering therapy in patients with and without HIV infection.
HIV Infections
Retroviruses and opportunistic infections--eighth annual conference--structured therapy interruption.
HIV Infections
Reversal of abnormalities of neutrophil adhesion molecule expression in HIV infection following protease inhibitor therapy.
HIV Infections
Rezolsta® (Darunavir/Cobicistat): First Boosted Protease Inhibitor Co-formulated with Cobicistat.
HIV Infections
Rheumatological complications associated with the use of indinavir and other protease inhibitors.
HIV Infections
Risk factors for acute liver enzyme abnormalities in HIV-hepatitis B virus-coinfected patients on antiretroviral therapy.
HIV Infections
Role of Fas ligand and receptor in the mechanism of T-cell depletion in acquired immunodeficiency syndrome: effect on CD4+ lymphocyte depletion and human immunodeficiency virus replication.
HIV Infections
Role of protease inhibitors in preventing recurrent oral candidosis in patients with HIV infection: a prospective case-control study.
HIV Infections
Rosuvastatin versus pravastatin in dyslipidemic HIV-1-infected patients receiving protease inhibitors: a randomized trial.
HIV Infections
Safety and pharmacokinetics of once-daily regimens of soft-gel capsule saquinavir plus minidose ritonavir in human immunodeficiency virus-negative adults.
HIV Infections
Saquinavir enhances the mucosal toxicity of infusional cyclophosphamide, doxorubicin, and etoposide in patients with HIV-associated non-Hodgkin's lymphoma.
HIV Infections
Saquinavir inhibits the malaria parasite's chloroquine resistance transporter.
HIV Infections
Saquinavir soft-gel capsule: an updated review of its use in the management of HIV infection.
HIV Infections
Saquinavir. A review of its pharmacology and clinical potential in the management of HIV infection.
HIV Infections
Saquinavir: a review of its use in boosted regimens for treating HIV infection.
HIV Infections
Sensitivity analysis of a nonlinear lumped parameter model of HIV infection dynamics.
HIV Infections
Short-term effects of cannabinoids in patients with HIV-1 infection: a randomized, placebo-controlled clinical trial.
HIV Infections
Simplification of antiretroviral treatment--how to sustain success, reduce toxicity and ensure adherence avoiding PI use.
HIV Infections
Simplification to coformulated elvitegravir, cobicistat, emtricitabine, and tenofovir versus continuation of ritonavir-boosted protease inhibitor with emtricitabine and tenofovir in adults with virologically suppressed HIV (STRATEGY-PI): 48 week results of a randomised, open-label, phase 3b, non-inferiority trial.
HIV Infections
Simplifying the treatment of HIV infection with ritonavir-boosted protease inhibitors in antiretroviral-experienced patients.
HIV Infections
Simultaneous determination of indinavir, ritonavir and saquinavir in plasma by high-performance liquid chromatography.
HIV Infections
Simultaneous Population Pharmacokinetic Model for Lopinavir and Ritonavir in HIV-Infected Adults.
HIV Infections
Six-week randomized controlled trial to compare the tolerabilities, pharmacokinetics, and antiviral activities of GW433908 and amprenavir in human immunodeficiency virus type 1-infected patients.
HIV Infections
Special populations and pharmacogenetic issues in tuberculosis drug development and clinical research.
HIV Infections
ST-elevation myocardial infarction due to a spontaneous thrombus in the left anterior descending artery in a young HIV-infected patient.
HIV Infections
State-of-the-art tools unveil potent drug targets amongst clinically approved drugs to inhibit helicase in SARS-CoV-2.
HIV Infections
Structural insights into the South African HIV-1 subtype C protease: impact of hinge region dynamics and flap flexibility in drug resistance.
HIV Infections
Structure-based design of HIV protease inhibitors: 5,6-dihydro-4-hydroxy-2-pyrones as effective, nonpeptidic inhibitors.
HIV Infections
Switch to etravirine for HIV-positive patients receiving statin treatment: a prospective study.
HIV Infections
The absorption, distribution, metabolism and elimination of bevirimat in rats.
HIV Infections
The antiretroviral agent saquinavir enhances hTERT expression and telomerase activity in human T leukaemia cells in vitro.
HIV Infections
The beta-chemokines MIP-1alpha and RANTES and lipoprotein metabolism in HIV-infected Brazilian patients.
HIV Infections
The choice of HIV protease inhibitor: indinavir is currently the best option.
HIV Infections
The current role of ritonavir-boosted protease inhibitors in the management of HIV infection.
HIV Infections
The danish protease inhibitor study: a randomized study comparing the virological efficacy of 3 protease inhibitor-containing regimens for the treatment of human immunodeficiency virus type 1 infection.
HIV Infections
The discovery of a class of novel HIV-1 maturation inhibitors and their potential in the therapy of HIV.
HIV Infections
The effect of protease inhibitors on weight and body composition in HIV-infected patients.
HIV Infections
The effect of switching protease inhibitors to raltegravir on endothelial function, in HIV-infected patients.
HIV Infections
The emerging roles of non-nucleoside reverse transcriptase inhibitors in antiretroviral therapy.
HIV Infections
The HIV protease inhibitor indinavir impairs sterol regulatory element-binding protein-1 intranuclear localization, inhibits preadipocyte differentiation, and induces insulin resistance.
HIV Infections
The HIV protease inhibitor nelfinavir inhibits Kaposi sarcoma-associated herpesvirus replication in vitro.
HIV Infections
The HIV protease inhibitor saquinavir impairs lipid metabolism and glucose transport in cultured adipocytes.
HIV Infections
The insulin-like growth factor system in human immunodeficiency virus infection: relations to immunological parameters, disease progression, and antiretroviral therapy.
HIV Infections
The nucleoside reverse transcriptase inhibitors, nonnucleoside reverse transcriptase inhibitors, and protease inhibitors in the treatment of HIV infections (AIDS).
HIV Infections
The role of pharmacological enhancement in protease inhibitor-based highly active antiretroviral therapy.
HIV Infections
The thoracic surgeon's role in the management of patients with HIV infection and AIDS.
HIV Infections
Therapeutic drug monitoring and drug-drug interactions involving antiretroviral drugs.
HIV Infections
Tipranavir: a novel non-peptidic protease inhibitor for the treatment of HIV infection.
HIV Infections
Tolerability and efficacy of PI versus NNRTI-based regimens in subjects receiving HAART during acute or early HIV infection.
HIV Infections
Toxicity, efficacy, plasma drug concentrations and protease mutations in patients with advanced HIV infection treated with ritonavir plus saquinavir. Swiss HIV Cohort Study.
HIV Infections
Treatment of indinavir sulfate induced urolithiasis in HIV-positive patients.
HIV Infections
Trimethoprim-sulfamethoxazole (TMP/SMX) potentiates indinavir nephrotoxicity.
HIV Infections
Ultrasonographic backscatter of the carotid artery wall in patients with HIV infection: A pilot study.
HIV Infections
Unboosted atazanavir for treatment of HIV infection: rationale and recommendations for use.
HIV Infections
Understanding the HIV-1 protease nelfinavir resistance mutation D30N in subtypes B and C through molecular dynamics simulations.
HIV Infections
Unusual binding mode of an HIV-1 protease inhibitor explains its potency against multi-drug-resistant virus strains.
HIV Infections
Urological management of indinavir-associated acute renal failure in HIV-positive patients.
HIV Infections
Use of Boosted Protease Inhibitors Reduces Kaposi Sarcoma Incidence Among Male Veterans With HIV Infection.
HIV Infections
Use of combination antiretroviral therapy in pregnant women with HIV disease.
HIV Infections
Using pharmacokinetics to optimize antiretroviral drug-drug interactions in the treatment of human immunodeficiency virus infection.
HIV Infections
Validation of estimated renal function measurements compared with the isotopic glomerular filtration rate in an HIV-infected cohort.
HIV Infections
Variability in the PR and RT genes of HIV-1 isolated from recently infected subjects.
HIV Infections
Variability of attitudes toward early initiation of HAART for HIV infection: a study of French prescribing physicians.
HIV Infections
Viral load of the human immunodeficiency virus could be an independent risk factor for endothelial dysfunction.
HIV Infections
Virological and immunological impact of integrase inhibitor-based regimens initiated during primary HIV-1 infection.
HIV Infections
Visceral obesity, hypertriglyceridemia and hypercortisolism in a boy with perinatally acquired HIV infection receiving protease inhibitor-containing antiviral treatment.
HIV Infections
Vitamin D insufficiency is associated with subclinical atherosclerosis in HIV-1-infected patients on combination antiretroviral therapy.
HIV Infections
Zalcitabine. An update of its pharmacodynamic and pharmacokinetic properties and clinical efficacy in the management of HIV infection.
HIV Infections
Zidovudine: a review of its use in the management of vertically-acquired pediatric HIV infection.
HIV Infections
["Buffalo neck": an unintended secondary effect of treatment with anti-HIV protease inhibitors]
HIV Infections
[AIDS Study Group/Spanish AIDS Plan consensus document on antiretroviral therapy in adults with human immunodeficiency virus infection (updated January 2010)]
HIV Infections
[Benign symmetrical lipomatosis ("peripheral lipodystrophy") during antiretroviral therapy of HIV infection]
HIV Infections
[Clinical and immuno-virologic efficacy of the expanded access use of protease inhibitors for HIV-1 advanced disease]
HIV Infections
[Clinical studies on the use of protease inhibitors in HIV infection. Answers and questions]
HIV Infections
[Diabetes and hyperglycemia in patients under treatment for HIV infection with the protease inhibitors indavir, ritonavir, saquinavir as well as nelfinavir (in development, but not yet released]
HIV Infections
[Factors predictive of early virologic response after a first treatment with an protease inhibitor in the course of HIV infection]
HIV Infections
[Human immunodeficiency virus infection: physiopathological approach to specific therapeutic strategies]
HIV Infections
[Hyperlipidemia in patients with HIV infection treated with protease inhibitors]
HIV Infections
[Implications of antiretroviral therapy in oral medicine--a review of literature]
HIV Infections
[Long-term efficacy of second-line treatment of HIV infection after class change following virological failure on protease inhibitor-based therapy]
HIV Infections
[Modern methods of detection of HIV resistance to the action of anti-retroviral agents]
HIV Infections
[Pharmacological study and clinical effect of HIV protease inhibitor amprenavir]
HIV Infections
[Predictive factors of virologic response to antiretroviral treatment with a protease inhibitor in HIV infection]
HIV Infections
[Protease inhibitor Kaletra (Lopinavir/Ritonavir): significance and role in antiretroviral therapy of HIV infection and AIDS]
HIV Infections
[Recommendations from the GESIDA/Spanish AIDS Plan regarding antiretroviral treatment in adults with human immunodeficiency virus infection (update February 2009).]
HIV Infections
[Recommendations from the GESIDA/Spanish AIDS Plan regarding antiretroviral treatment in adults with human immunodeficiency virus infection (update January 2007)]
HIV Infections
[Safety of atazanavir in patients with HIV and hepatitis B and/or C virus coinfection]
HIV Infections
[The lipodystrophy syndrome and protease inhibitor therapy in HIV infection]
HIV Infections
[Treatment of HIV infection in clinical practice. Wide-range genotypic resistance to all nucleoside analogues and protease inhibitors, and severe intolerance to all non-nucleoside inhibitors of inverse transcriptase]
HIV Infections
[Treatment of HIV infections and AIDS with protease inhibitor and two nucleoside analogs]
HIV-Associated Lipodystrophy Syndrome
Antiretroviral treatment simplification with nevirapine in protease inhibitor-experienced patients with hiv-associated lipodystrophy: 1-year prospective follow-up of a multicenter, randomized, controlled study.
HIV-Associated Lipodystrophy Syndrome
Cutaneous toxicities of antiretroviral therapy for HIV: part I. Lipodystrophy syndrome, nucleoside reverse transcriptase inhibitors, and protease inhibitors.
HIV-Associated Lipodystrophy Syndrome
Effect of ritonavir and atazanavir on human subcutaneous preadipocyte proliferation and differentiation.
HIV-Associated Lipodystrophy Syndrome
Fat distribution and metabolic changes are strongly correlated and energy expenditure is increased in the HIV lipodystrophy syndrome.
HIV-Associated Lipodystrophy Syndrome
HIV-related lipodystrophy and facial lipoatrophy: The role of Restylane SubQ in reversing facial wasting.
HIV-Associated Lipodystrophy Syndrome
Improvement of fat redistribution, insulin resistance and hepatic fatty infiltration in HIV-associated lipodystrophy syndrome by pioglitazone: a case report.
HIV-Associated Lipodystrophy Syndrome
The role of protease inhibitors in the pathogenesis of HIV-associated lipodystrophy: cellular mechanisms and clinical implications.
Hodgkin Disease
Characterization of the interleukin-1beta-converting enzyme/ced-3-family protease, caspase-3/CPP32, in Hodgkin's disease: lack of caspase-3 expression in nodular lymphocyte predominance Hodgkin's disease.
Hodgkin Disease
Detrimental clinical interaction between ritonavir-boosted protease inhibitors and vinblastine in HIV-infected patients with Hodgkin's lymphoma.
Hodgkin Disease
Excessive neurotoxicity with ABVD when combined with protease inhibitor-based antiretroviral therapy in the treatment of AIDS-related Hodgkin lymphoma.
Hodgkin Disease
Expression of the granzyme B inhibitor, protease inhibitor 9, by tumor cells in patients with non-Hodgkin and Hodgkin lymphoma: a novel protective mechanism for tumor cells to circumvent the immune system?
Hodgkin Disease
Gilbert-Meulengracht's syndrome and pharmacogenetics: is jaundice just the tip of the iceberg?
Hodgkin Disease
Hodgkin disease: pharmacologic intervention of the CD40-NF kappa B pathway by a protease inhibitor.
Hodgkin Disease
Immunohistochemical analysis of interleukin-1beta-converting enzyme/Ced-3 family protease, CPP32/Yama/Caspase-3, in Hodgkin's disease.
Hodgkin Disease
Potential hazard drug-drug interaction between boosted protease inhibitors and vinblastine in HIV patients with Hodgkin's lymphoma.
Hodgkin Disease
Prognostic significance of activated cytotoxic T-lymphocytes in primary nodal diffuse large B-cell lymphomas.
Hodgkin Disease
Protease receptors in Hodgkin's disease: expression of the factor Xa receptor, effector cell protease receptor-1, in Reed-Sternberg cells.
Hodgkin Disease
Studies of lectin binding to normal and neoplastic lymphoid tissues. I. Normal nodes and Hodgkin's disease.
Hodgkin Disease
Survival in HIV-infected patients with lymphoma according to the choice of antiretroviral treatment: an observational multicentre study.
Homocystinuria
X-ray imaging of differential vascular density in MMP-9-/-, PAR-1-/+, hyperhomocysteinemic (CBS-/+) and diabetic (Ins2-/+) mice*
HTLV-I Infections
HTLV-I protease cleavage of P19/24 substrates is not dependent on NaCl concentration.
Huntington Disease
A whole cell assay to measure caspase-6 activity by detecting cleavage of lamin A/C.
Huntington Disease
Caspase vinyl sulfone small molecule inhibitors prevent axonal degeneration in human neurons and reverse cognitive impairment in Caspase-6-overexpressing mice.
Huntington Disease
Comparison of cathepsin protease activities in brain tissue from normal cases and cases with Alzheimer's disease, Lewy body dementia, Parkinson's disease and Huntington's disease.
Huntington Disease
Idebenone and resveratrol extend lifespan and improve motor function of HtrA2 knockout mice.
Huntington Disease
Potential of protease inhibitor in 3-nitropropionic acid induced Huntington's disease like symptoms: mitochondrial dysfunction and neurodegeneration.
Huntington Disease
The regulatory mechanism of the caspase 6 pro-domain revealed by crystal structure and biochemical assays.
Hydatidiform Mole
The expression of cathepsin D, oestrogen receptor and progestogen receptor in hydatidiform mole--an immunohistochemical study.
Hyperalgesia
A low dose of fermented soy germ alleviates gut barrier injury, hyperalgesia and faecal protease activity in a rat model of inflammatory bowel disease.
Hyperalgesia
Characterization and preclinical evaluation of a protease activated receptor 2 (PAR2) monoclonal antibody as a preventive therapy for migraine.
Hyperalgesia
Decreased concentration of protease inhibitors: possible contributors to allodynia and hyperalgesia in women with vestibulodynia.
Hyperalgesia
Increased faecal serine protease activity in diarrhoeic IBS patients: a colonic lumenal factor impairing colonic permeability and sensitivity.
Hyperalgesia
Involvement of mast cells and proteinase-activated receptor 2 in oxaliplatin-induced mechanical allodynia in mice.
Hyperalgesia
Protease activated receptor 2 (PAR2) activation causes migraine-like pain behaviors in mice.
Hyperalgesia
Transient receptor potential vanilloid 4 mediates protease activated receptor 2-induced sensitization of colonic afferent nerves and visceral hyperalgesia.
Hyperalgesia
Trypsinogen IV, serotonin transporter transcript levels and serotonin content are increased in small intestine of irritable bowel syndrome patients.
Hypercalcemia
Acute hypercalcemia causes acute pancreatitis and ectopic trypsinogen activation in the rat.
Hypercalcemia
Cinacalcet sustainedly prevents pancreatitis in a child with a compound heterozygous SPINK1/AP2S1 mutation.
Hypercalcemia
Modified immunoradiometric assay of parathyroid hormone-related protein: clinical application in the differential diagnosis of hypercalcemia.
Hypercholesterolemia
A 48-week, randomized, open-label comparison of three abacavir-based substitution approaches in the management of dyslipidemia and peripheral lipoatrophy.
Hypercholesterolemia
A new PCSK9 gene promoter variant affects gene expression and causes autosomal dominant hypercholesterolemia.
Hypercholesterolemia
A Spectrum of PCSK9 Alleles Contributes to Plasma Levels of Low-Density Lipoprotein Cholesterol.
Hypercholesterolemia
Association of Hypercholesterolemia Incidence With Antiretroviral Treatment, Including Protease Inhibitors, Among Perinatally HIV-Infected Children.
Hypercholesterolemia
Cardiovascular disease in patients infected with the human immunodeficiency virus.
Hypercholesterolemia
CD36 overexpression in ritonavir-treated THP-1 cells is reversed by alpha-tocopherol.
Hypercholesterolemia
Decrease in enkephalinase A number in kidney membranes from hypercholesterolemic and hypertensive rats.
Hypercholesterolemia
Dyslipidemia in a Cohort of HIV-infected Latin American Children Receiving Highly Active Antiretroviral Therapy.
Hypercholesterolemia
Dyslipidemia, Diet and Physical Exercise in Children on Treatment With Antiretroviral Medication in El Salvador: A Cross-sectional Study.
Hypercholesterolemia
H-risk dysmetabolism disorders associated with HAART-treated HIV disease, and reimbursement of lipid-lowering drugs, in a clinical and a socio-economic perspective.
Hypercholesterolemia
HIV protease inhibitors promote atherosclerotic lesion formation independent of dyslipidemia by increasing CD36-dependent cholesteryl ester accumulation in macrophages.
Hypercholesterolemia
Hypercholesterolemia Is Associated with the Apolipoprotein C-III (APOC3) Genotype in Children Receiving HAART: An Eight-Year Retrospective Study.
Hypercholesterolemia
Hypertriglyceridemia and hypercholesterolemia in human immunodeficiency virus-1-infected children treated with protease inhibitors.
Hypercholesterolemia
Lipid profile and renal safety of tenofovir disoproxil fumarate-based anti-retroviral therapy in HIV-infected Chinese patients.
Hypercholesterolemia
Lipid profile of HIV-infected patients in relation to antiretroviral therapy: a review.
Hypercholesterolemia
Low LDL cholesterol in individuals of African descent resulting from frequent nonsense mutations in PCSK9.
Hypercholesterolemia
Proprotein convertase subtilisin/kexin type 9: A new target molecule for gene therapy.
Hypercholesterolemia
Safety and efficacy of a monoclonal antibody to proprotein convertase subtilisin/kexin type 9 serine protease, SAR236553/REGN727, in patients with primary hypercholesterolemia receiving ongoing stable atorvastatin therapy.
Hypercholesterolemia
The beta-chemokines MIP-1alpha and RANTES and lipoprotein metabolism in HIV-infected Brazilian patients.
Hypercholesterolemia
The therapeutic potential of PCSK9 inhibition in primary dyslipidemia, the example from SAR236553/REGN727 McKenney JM, Koren MJ, Kereiakes DJ, Hanotin C, Ferrand AC, Stein EA. Safety and efficacy of a monoclonal antibody to proprotein convertase Subtilisin/Kexin type 9 serine protease, SAR236553/REGN727, in patients with primary hypercholesterolemia receiving ongoing stable atorvastatin therapy. J Am Coll Cardiol 2012. [Epub ahead of print].
Hypercholesterolemia
Tipranavir: a new option for the treatment of drug-resistant HIV infection.
Hypercholesterolemia
Use of fenofibrate in the management of protease inhibitor-associated lipid abnormalities.
Hypercholesterolemia
[Epidemiology of the metabolic abnormalities in patients with HIV infections]
Hyperemia
Gastric mucosal inflammatory responses toHelicobacter pylori lipopolysaccharide: Suppression of caspase-3 and nitric oxide synthase-2 by omeprazole and sucralfate.
Hyperglycemia
Chronic hyperglycemia impairs mitochondrial unfolded protein response and precipitates proteotoxicity in experimental diabetic neuropathy: focus on LonP1 mediated mitochondrial regulation.
Hyperglycemia
Effects of protease inhibitors on hyperglycemia, hyperlipidemia, and lipodystrophy: a 5-year cohort study.
Hyperglycemia
Human obesity and thinness, hyperlipidemia, hyperglycemia, and insulin resistance associated with HIV1 protease inhibitors. Prevention by alternating several antiproteases in short sequences.
Hyperglycemia
Hyperglycemia associated with protease inhibitors in an urban HIV-infected minority patient population.
Hyperglycemia
Hyperglycemia associated with protease inhibitors in HIV-1-infected patients.
Hyperglycemia
Hyperglycemia is a major determinant of albumin permeability in diabetic microcirculation: the role of mu-calpain.
Hyperglycemia
Hyperglycemia potentiates carbonyl stress-induced apoptosis in naïve PC-12 cells: relationship to cellular redox and activator protease factor-1 expression.
Hyperglycemia
Inhibition of Serine Protease Activity Protects Against High Fat Diet-Induced Inflammation and Insulin Resistance.
Hyperglycemia
LONP1 induction by SRT1720 attenuates mitochondrial dysfunction against high glucose induced neurotoxicity in PC12 cells.
Hyperglycemia
Periodontal disease, diabetes, and immune response: a review of current concepts.
Hyperglycemia
Prospective evaluation of the effect of initiating indinavir-based therapy on insulin sensitivity and B-cell function in HIV-infected patients.
Hyperglycemia
Protease inhibitor-associated hyperglycemia in Mexican patients with HIV infection.
Hyperglycemia
Risks of cardiovascular disease in patients receiving antiretroviral therapy for HIV infection: implications for treatment.
Hyperglycemia
The association between HIV, antiretroviral therapy, and gestational diabetes mellitus.
Hyperglycemia
The effect of HAART and HCV infection on the development of hyperglycemia among HIV-infected persons.
Hyperglycemia
Tuberous and tendinous xanthomata secondary to ritonavir-associated hyperlipidemia.
Hyperglycemia
[Diabetes and hyperglycemia in patients under treatment for HIV infection with the protease inhibitors indavir, ritonavir, saquinavir as well as nelfinavir (in development, but not yet released]
Hyperhomocysteinemia
X-ray imaging of differential vascular density in MMP-9-/-, PAR-1-/+, hyperhomocysteinemic (CBS-/+) and diabetic (Ins2-/+) mice*
Hyperinsulinism
Body-composition measurements as predictors of glucose and insulin abnormalities in HIV-positive men.
Hyperinsulinism
Endocrine and metabolic evaluation of human immunodeficiency virus-infected patients with evidence of protease inhibitor-associated lipodystrophy.
Hyperinsulinism
Fasting hyperinsulinemia in human immunodeficiency virus-infected men: relationship to body composition, gonadal function, and protease inhibitor use.
Hyperinsulinism
Metformin decreases the adipokine vaspin in overweight women with polycystic ovary syndrome concomitant with improvement in insulin sensitivity and a decrease in insulin resistance.
Hyperlactatemia
Chronic hyperlactatemia in HIV-infected patients taking antiretroviral therapy.
Hyperlactatemia
Lactate levels in children with HIV/AIDS on highly active antiretroviral therapy.
Hyperlipidemias
Adverse metabolic consequences of HIV protease inhibitor therapy: the search for a central mechanism.
Hyperlipidemias
Antiretroviral drugs and acute pancreatitis in HIV/AIDS patients: is there any association? A literature review.
Hyperlipidemias
Atazanavir induced first degree atrioventricular block and ventricular tachycardia: a case report.
Hyperlipidemias
Atazanavir/ritonavir-based combination antiretroviral therapy for treatment of HIV-1 infection in adults.
Hyperlipidemias
Atherogenic dyslipidemia in HIV-infected individuals treated with protease inhibitors. The Swiss HIV Cohort Study.
Hyperlipidemias
Avascular necrosis of bone in patients with human immunodeficiency virus infection: report of 6 cases and review of the literature.
Hyperlipidemias
Blunted lipolysis and fatty acid oxidation during moderate exercise in HIV-infected subjects taking HAART.
Hyperlipidemias
Effect of antiretroviral therapy use and adherence on the risk of hyperlipidemia among HIV-infected patients, in the highly active antiretroviral therapy era.
Hyperlipidemias
Effects of protease inhibitors on hyperglycemia, hyperlipidemia, and lipodystrophy: a 5-year cohort study.
Hyperlipidemias
Efficacy and safety of atazanavir-ritonavir plus abacavir-lamivudine or tenofovir-emtricitabine in patients with hyperlipidaemia switched from a stable protease inhibitor-based regimen including one thymidine analogue.
Hyperlipidemias
Electron beam computed tomography for assessment of coronary artery disease in HIV-infected men receiving antiretroviral therapy.
Hyperlipidemias
Fat redistribution in indinavir-treated patients with HIV infection: A review of postmarketing cases.
Hyperlipidemias
HIV protease inhibitor induces fatty acid and sterol biosynthesis in liver and adipose tissues due to the accumulation of activated sterol regulatory element-binding proteins in the nucleus.
Hyperlipidemias
HIV protease inhibitors protect apolipoprotein B from degradation by the proteasome: a potential mechanism for protease inhibitor-induced hyperlipidemia.
Hyperlipidemias
HIV-associated vascular diseases: structural and functional changes, clinical implications.
Hyperlipidemias
Human obesity and thinness, hyperlipidemia, hyperglycemia, and insulin resistance associated with HIV1 protease inhibitors. Prevention by alternating several antiproteases in short sequences.
Hyperlipidemias
Hyperlipidemia and insulin resistance are induced by protease inhibitors independent of changes in body composition in patients with HIV infection.
Hyperlipidemias
Hyperlipidemia associated with HIV protease inhibitor use: pathophysiology, prevalence, risk factors and treatment.
Hyperlipidemias
Hyperlipidemia in HIV-infected children treated with protease inhibitors: relevance for cardiovascular diseases.
Hyperlipidemias
Hyperlipidemia related to the use of HIV-protease inhibitors: natural history and results of treatment with fenofibrate.
Hyperlipidemias
Identification of proteasome gene regulation in a rat model for HIV protease inhibitor-induced hyperlipidemia.
Hyperlipidemias
Increased use of lipid-lowering therapy in patients receiving human immunodeficiency virus protease inhibitors.
Hyperlipidemias
Indinavir did not further increase mean triglyceride levels in HIV-infected patients treated with nucleoside reverse transcriptase inhibitors: an analysis of three randomized clinical trials.
Hyperlipidemias
Insulin resistance in HIV infection: drugs, host responses, or restoration to health?
Hyperlipidemias
Lipemia retinalis as a presenting feature of hypertriglyceridemia associated with protease inhibitors in human immunodeficiency virus-infected patients.
Hyperlipidemias
Lipemia retinalis in acquired immunodeficiency syndrome treated with protease inhibitors.
Hyperlipidemias
Lipodystrophic syndromes and hyperlipidemia in a cohort of HIV-1-infected patients receiving triple combination antiretroviral therapy with a protease inhibitor.
Hyperlipidemias
Longer-term immunologic effects and side effects of successful antiretroviral therapy.
Hyperlipidemias
Lovastatin potentiates antitumor effects of saquinavir against human lymphoma cells.
Hyperlipidemias
Mechanisms of intimal hyperplasia learned from a murine carotid artery ligation model.
Hyperlipidemias
Metabolic and neurologic consequences of chronic lopinavir/ritonavir administration to C57BL/6 mice.
Hyperlipidemias
Metabolic disorders among HIV-infected patients treated with protease inhibitors: a review.
Hyperlipidemias
Mg-supplementation Attenuates Ritonavir-induced Hyperlipidemia, Oxidative Stress and Cardiac Dysfunction in Rats.
Hyperlipidemias
Plasmapheresis in the treatment of an acute pancreatitis due to protease inhibitor-induced hypertriglyceridemia.
Hyperlipidemias
Prevalence and incidence of diabetes in HIV-infected minority patients on protease inhibitors.
Hyperlipidemias
Protease Inhibitor-Associated Dyslipidemia in HIV-Infected Patients Is Strongly Influenced by the APOA5-1131T->C Gene Variation.
Hyperlipidemias
Rationale and clinical utility of the darunavir-cobicistat combination in the treatment of HIV/AIDS.
Hyperlipidemias
Respiratory failure associated with the lipodystrophy syndrome in an HIV-positive patient with compromised lung function.
Hyperlipidemias
Review: thromboses among HIV-infected patients during the highly active antiretroviral therapy era.
Hyperlipidemias
Rhabdomyolysis after cerivastatin-gemfibrozil therapy in an HIV-infected patient with protease inhibitor-related hyperlipidemia.
Hyperlipidemias
Substituting abacavir for hyperlipidemia-associated protease inhibitors in HAART regimens improves fasting lipid profiles, maintains virologic suppression, and simplifies treatment.
Hyperlipidemias
Syndrome of lipodystrophy, hyperlipidemia, insulin resistance, and diabetes in treated patients with human immunodeficiency virus infection.
Hyperlipidemias
The mechanism of insulin resistance caused by HIV protease inhibitor therapy.
Hyperlipidemias
Tuberous and tendinous xanthomata secondary to ritonavir-associated hyperlipidemia.
Hyperlipidemias
[Hyperlipidemia in patients with HIV infection treated with protease inhibitors]
Hyperlipoproteinemia Type II
A Spectrum of PCSK9 Alleles Contributes to Plasma Levels of Low-Density Lipoprotein Cholesterol.
Hyperlipoproteinemia Type II
CONSENSUS STATEMENT BY THE AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS AND AMERICAN COLLEGE OF ENDOCRINOLOGY ON THE COMPREHENSIVE TYPE 2 DIABETES MANAGEMENT ALGORITHM - 2019 EXECUTIVE SUMMARY.
Hyperlipoproteinemia Type II
CONSENSUS STATEMENT BY THE AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS AND AMERICAN COLLEGE OF ENDOCRINOLOGY ON THE COMPREHENSIVE TYPE 2 DIABETES MANAGEMENT ALGORITHM - 2020 EXECUTIVE SUMMARY.
Hyperlipoproteinemia Type II
Low-density lipoprotein cholesterol-lowering effects of AMG 145, a monoclonal antibody to proprotein convertase subtilisin/kexin type 9 serine protease in patients with heterozygous familial hypercholesterolemia: the Reduction of LDL-C with PCSK9 Inhibition in Heterozygous Familial Hypercholesterolemia Disorder (RUTHERFORD) randomized trial.
Hyperopia
Müller glia-derived PRSS56 is required to sustain ocular axial growth and prevent refractive error.
Hyperpigmentation
Fixed drug eruptions to human immunodeficiency virus-1 protease inhibitor.
Hyperprolactinemia
Galactorrhoea, hyperprolactinaemia, and protease inhibitors.
Hypersensitivity
A murine model of wheat versus potato allergy: Patatin and 53kDa protein are the potential allergen from potato.
Hypersensitivity
A new soy germ fermented ingredient displays estrogenic and protease inhibitor activities able to prevent irritable bowel syndrome-like symptoms in stressed female rats.
Hypersensitivity
A Novel Aza-MBP Altered Peptide Ligand for the Treatment of Experimental Autoimmune Encephalomyelitis.
Hypersensitivity
A protease inhibitor against acute stress-induced visceral hypersensitivity and paracellular permeability in rats.
Hypersensitivity
A viral infection explanation for Kawasaki disease in general and for COVID-19 virus-related Kawasaki disease symptoms.
Hypersensitivity
Allergen Delivery Inhibitors: Characterisation of Potent and Selective Inhibitors of Der p 1 and Their Attenuation of Airway Responses to House Dust Mite Allergens.
Hypersensitivity
Allergic reactions, including asthma, to the pineapple protease bromelain following occupational exposure.
Hypersensitivity
An explanation of the pathogenesis of several autoimmune diseases in immuno-compromised individuals.
Hypersensitivity
Basophils as Key Regulators of Allergic Inflammation and Th2-type Immunity.
Hypersensitivity
Biotin deficiency in an infant fed with amino acid formula and hypoallergenic rice.
Hypersensitivity
Chitin enhances serum IgE in Aspergillus fumigatus induced allergy in mice.
Hypersensitivity
Clinical ritonavir and lopinavir hypersensitivity confirmed by a specific in vitro cellular allergen stimulation test.
Hypersensitivity
Cockroach protease allergen induces allergic airway inflammation via epithelial cell activation.
Hypersensitivity
Communication of ClpXP protease hypersensitivity to bacteriophage Mu repressor isoforms.
Hypersensitivity
Continued therapy with HIV-1 protease inhibitors, despite previous hypersensitivity reactions, through coadministration of prednisone.
Hypersensitivity
Current perspectives and recommendations for the development of mass spectrometry methods for the determination of allergens in foods.
Hypersensitivity
Effect of proteolytic activity of Epicoccum purpurascens major allergen, Epi p 1 in allergic inflammation.
Hypersensitivity
Epithelial expression and function of trypsin-3 in irritable bowel syndrome.
Hypersensitivity
Fish muscle processing into seafood products reduces ?-parvalbumin allergenicity.
Hypersensitivity
Generation, characterization and structural data of chymase binding proteins based on the human Fyn kinase SH3 domain.
Hypersensitivity
Growth, phenotype, and function of human intestinal mast cells are tightly regulated by transforming growth factor beta1.
Hypersensitivity
Human and guinea pig immune responses to Legionella pneumophila protein antigens OmpS and Hsp60.
Hypersensitivity
Hypersensitivity reactions during antiretroviral regimens with protease inhibitors.
Hypersensitivity
Identification and partial purification of serologically defined Boophilus microplus larval antigens by natural ectoparasite exposure.
Hypersensitivity
Identification of the cysteine protease Amb a 11 as a novel major allergen from short ragweed.
Hypersensitivity
In vivo and transgenic animal models used to study visceral hypersensitivity.
Hypersensitivity
Increased production of BDNF in colonic epithelial cells induced by fecal supernatants from diarrheic IBS patients.
Hypersensitivity
Inhibition of CD26/dipeptidyl peptidase IV enhances CCL11/eotaxin-mediated recruitment of eosinophils in vivo.
Hypersensitivity
Inhibition of the formation of hypersensitivity pyrogen from delayed hypersensitive cell extract by protease inhibitors in vitro.
Hypersensitivity
Isolation of a thiol-dependent serine protease in peanut and investigation of its role in the complement and the allergic reaction.
Hypersensitivity
Local Colonic Administration of a Serine Protease Inhibitor Improves Post-Inflammatory Visceral Hypersensitivity in Rats.
Hypersensitivity
Lysosomal proteases and protease inhibitors in nasal allergy and non-atopic sinusitis.
Hypersensitivity
Mite serine protease activates protease-activated receptor-2 and induces cytokine release in human keratinocytes.
Hypersensitivity
Netherton syndrome: skin inflammation and allergy by loss of protease inhibition.
Hypersensitivity
Newly developed serine protease inhibitors decrease visceral hypersensitivity in a post-inflammatory rat model for irritable bowel syndrome.
Hypersensitivity
Osmoregulated periplasmic glucan synthesis is required for Erwinia chrysanthemi pathogenicity.
Hypersensitivity
Predominance of IgG1 and IgG4 subclasses of anti-neutrophil cytoplasmic autoantibodies (ANCA) in patients with Wegener's granulomatosis and clinically related disorders.
Hypersensitivity
Presenilin-1 mutations sensitize neurons to DNA damage-induced death by a mechanism involving perturbed calcium homeostasis and activation of calpains and caspase-12.
Hypersensitivity
Protease activated receptor 2 (PAR2) activation causes migraine-like pain behaviors in mice.
Hypersensitivity
Protease Activated Receptor-2 Induces Immune Activation and Visceral Hypersensitivity in Post-infectious Irritable Bowel Syndrome Mice.
Hypersensitivity
Protease activated-receptor 4 activation as a model of persistent bladder pain: Essential role of macrophage migration inhibitory factor and high mobility group box 1.
Hypersensitivity
Recombinant Der p 1 and Der f 1 with in vitro enzymatic activity to cleave human CD23, CD25 and alpha1-antitrypsin, and in vivo IgE-eliciting activity in mice.
Hypersensitivity
Review and application of serine protease inhibition in coronary artery bypass graft surgery.
Hypersensitivity
Selective inactivation of USP18 isopeptidase activity in vivo enhances ISG15 conjugation and viral resistance.
Hypersensitivity
Serine protease inhibitor attenuates ovalbumin induced inflammation in mouse model of allergic airway disease.
Hypersensitivity
Serine protease inhibitor gabexate mesilate attenuates american cockroach-induced bronchial damage and inflammatory cytokine release.
Hypersensitivity
SERT and TPH-1 mRNA expression are reduced in Irritable Bowel Syndrome patients irrespective of visceral sensitivity state in large intestine.
Hypersensitivity
Serum trypsin inhibitory capacity and pi phenotypes. II. Prevalence of alpha1-antitrypsin deficiency in an allergy population.
Hypersensitivity
Short-term safety and tolerability of a once-daily fixed-dose abacavir-lamivudine combination versus twice-daily dosing of abacavir and lamivudine as separate components: findings from the ALOHA study.
Hypersensitivity
Spectrum of allergens for Japanese cedar pollinosis and impact of component-resolved diagnosis on allergen-specific immunotherapy.
Hypersensitivity
The 420K LEKTI variant alters LEKTI proteolytic activation and results in protease deregulation: implications for atopic dermatitis.
Hypersensitivity
The chemical mediation of delayed hypersensitivity skin reactions. IV. Activation of chemotactic factor precursor by a trypsin-like protease in guinea pig plasma.
Hypersensitivity
The significance of nasal protease inhibitor concentrations in house dust allergy.
Hypersensitivity
Vacuolar Serine Protease Is a Major Allergen of Fusarium proliferatum and an IgE-Cross Reactive Pan-Fungal Allergen.
Hypersensitivity
[Camostat mesilate, a protease inhibitor, inhibits visceral sensitivity and spinal c-fos expression in rats with acute restraint stress].
Hypersensitivity
[Protease inhibitory activities of nasal secretion on house dust mite allergen]
Hypersensitivity, Delayed
A high-molecular-weight trypsinlike protease in the skin sites of delayed hypersensitivity in guinea pigs.
Hypersensitivity, Delayed
An alkaline protease in the delayed hypersensitivity skin lesions in the guinea-pigs.
Hypersensitivity, Delayed
The chemical mediation of delayed hypersensitivity skin reactions. IV. Activation of chemotactic factor precursor by a trypsin-like protease in guinea pig plasma.
Hypersplenism
[Accessory use of protease-inhibiting agents for disease remission in a patient with autoimmune hemolytic anemia associated with B-CLL]
Hypertension
A novel angiotensin-? converting enzyme (ACE) inhibitory peptide from gastrointestinal protease hydrolysate of silkworm pupa (Bombyx mori) protein: Biochemical characterization and molecular docking study.
Hypertension
A serine protease inhibitor camostat mesilate prevents podocyte apoptosis and attenuates podocyte injury in metabolic syndrome model rats.
Hypertension
Antihypertensive effects of continuous oral administration of nattokinase and its fragments in spontaneously hypertensive rats.
Hypertension
Antithrombin III prevents blood pressure elevation and proteinuria induced by high salt intake in pregnant stroke-prone spontaneously hypertensive rats.
Hypertension
Bioengineering of an elastase inhibitor from Caesalpinia echinata (Brazil wood) seeds.
Hypertension
Brief Report: Impact of ART Classes on the Increasing Risk of Cerebral Small-Vessel Disease in Middle-Aged, Well-Controlled, cART-Treated, HIV-Infected Individuals.
Hypertension
Cardiometabolic risk among HIV-POSITIVE Ugandan adults: prevalence, predictors and effect of long-term antiretroviral therapy.
Hypertension
Cardiovascular abnormalities with normal blood pressure in tissue kallikrein-deficient mice.
Hypertension
Characterization of active anticoagulant fraction and a fibrin(ogen)olytic serine protease from leaves of Clerodendrum colebrookianum, a traditional ethno-medicinal plant used to reduce hypertension.
Hypertension
Common variation in KLKB1 and essential hypertension risk: tagging-SNP haplotype analysis in a case-control study.
Hypertension
Effect of casein hydrolysate, prepared with protease derived from Aspergillus oryzae, on subjects with high-normal blood pressure or mild hypertension.
Hypertension
Effect of short-term pancreatico-biliary duct obstruction with intraductal hypertension on subcellular organelle fragility and pancreatic adenylate energy metabolism in rats: protective effect of a new protease inhibitor, E-3123.
Hypertension
Effects of nebivolol on endothelial gene expression during oxidative stress in human umbilical vein endothelial cells.
Hypertension
Factors associated with statin selection among privately insured commercial and Medicare patients.
Hypertension
H-risk dysmetabolism disorders associated with HAART-treated HIV disease, and reimbursement of lipid-lowering drugs, in a clinical and a socio-economic perspective.
Hypertension
High prevalence of signs of renal damage despite normal renal function in a cohort of HIV-infected patients: evaluation of associated factors.
Hypertension
Hypertension among human immunodeficiency virus infected patients on treatment at Parirenyatwa Hospital: A descriptive study.
Hypertension
In vivo contribution of serine proteases to the proteolytic activation of ?ENaC in aldosterone-infused rats.
Hypertension
Incidence of primary hypertension in a population-based cohort of HIV-infected compared with non-HIV-infected persons and the effect of combined antiretroviral therapy.
Hypertension
Increased Klk9 Urinary Excretion Is Associated to Hypertension-Induced Cardiovascular Damage and Renal Alterations.
Hypertension
Mapping of the active site of proteases in the 1960s and rational design of inhibitors/drugs in the 1990s.
Hypertension
Mesangial cell gelatinase A synthesis is attenuated by oscillating hyperbaric pressure.
Hypertension
Molecular Implications of Natriuretic Peptides in the Protection from Hypertension and Target Organ Damage Development.
Hypertension
Myocardial matrix remodeling and the matrix metalloproteinases: influence on cardiac form and function.
Hypertension
Nephrotoxicity during tenofovir treatment: a three-year follow-up study in a Brazilian reference clinic.
Hypertension
Pharmacokinetics and pharmacodynamics of sildenafil in a patient treated with human immunodeficiency virus protease inhibitors.
Hypertension
Predictive factors of renal impairment in HIV-infected patients on antiretroviral therapy: Results from the VACH longitudinal cohort study.
Hypertension
Predictors of hypertension and changes of blood pressure in HIV-infected patients.
Hypertension
Prevalence of chronic kidney disease among HIV-1-infected patients receiving a combination antiretroviral therapy.
Hypertension
Prevalence of renal disease within an urban HIV-infected cohort in northern Italy.
Hypertension
Prospective single-arm observational study of human chymase inhibitor Polygonum hydropiper L in subjects with hypertension.
Hypertension
Protective effects of therapy with a protease and xanthine oxidase inhibitor in short form pancreatic biliary obstruction and ischemia in rats.
Hypertension
Proteolytic activation of the epithelial sodium channel and therapeutic application of a serine protease inhibitor for the treatment of salt-sensitive hypertension.
Hypertension
Risk factors for coronary heart disease in patients treated for human immunodeficiency virus infection compared with the general population.
Hypertension
Sildenafil and bosentan plasma concentrations in a human immunodeficiency virus- infected patient with pulmonary arterial hypertension treated with ritonavir-boosted protease inhibitor.
Hypertension
Structure of human pro-chymase: a model for the activating transition of granule-associated proteases.
Hypertension
Tenofovir-induced renal toxicity in 324 HIV-infected, antiretroviral-naïve patients.
Hypertension
Thiazolidinediones could improve endothelial dysfunction and risk of premature coronary heart disease in HIV-infected patients.
Hypertension
Visceral adipose tissue-derived serine protease inhibitor prevents the development of monocrotaline-induced pulmonary arterial hypertension in rats.
Hypertension
Vitamin D insufficiency is associated with subclinical atherosclerosis in HIV-1-infected patients on combination antiretroviral therapy.
Hypertension
[Factors associated with an abnormal ankle-braquial index in a cohort of patients with HIV-1 infection.]
Hypertension, Malignant
Association between thrombotic microangiopathy and reduced ADAMTS13 activity in malignant hypertension.
Hypertension, Portal
Cirrhosis associated with partial deficiency of alpha-1-antitrypsin: a clinical and autopsy study.
Hypertension, Pregnancy-Induced
Combination Antiretroviral Therapy and Hypertensive Disorders of Pregnancy.
Hypertension, Pulmonary
Physiology and pathophysiology of atrial natriuretic factor in lungs.
Hypertension, Pulmonary
Sildenafil Plasma Concentrations in Two HIV Patients with Pulmonary Hypertension Treated with Ritonavir-Boosted Protease Inhibitors.
Hypertensive Retinopathy
[Clinical reasoning and decision making in practice. A 39-year-old woman with somnolence, hypertension and haemolysis]
Hyperthyroidism
Early neuropsychological adverse events after switching from PI/r to dolutegravir could be related to hyperthyroidism in patients under levothyroxine.
Hypertriglyceridemia
A case-control study of HIV-associated pancreatic abnormalities during HAART era. Focus on emerging risk factors and specific management.
Hypertriglyceridemia
A randomized, double-blind study of gemfibrozil for the treatment of protease inhibitor-associated hypertriglyceridaemia.
Hypertriglyceridemia
Acute pancreatitis in HIV-infected patients: are etiologies changing since the introduction of protease inhibitor therapy?
Hypertriglyceridemia
Apoprotein c-III and E-containing lipoparticles are markedly increased in HIV-infected patients treated with protease inhibitors: association with the development of lipodystrophy.
Hypertriglyceridemia
Association of single-nucleotide polymorphism 3 and c.553G>T of APOA5 with hypertriglyceridemia after treatment with highly active antiretroviral therapy containing protease inhibitors in hiv-infected individuals in Taiwan.
Hypertriglyceridemia
Associations among Race/Ethnicity, ApoC-III Genotypes, and Lipids in HIV-1-Infected Individuals on Antiretroviral Therapy.
Hypertriglyceridemia
Attenuated T-lymphocyte response to HIV therapy in individuals receiving HMG-CoA reductase inhibitors.
Hypertriglyceridemia
Cardiovascular disease in patients infected with the human immunodeficiency virus.
Hypertriglyceridemia
Decrease in LDL size in HIV-positive adults before and after lopinavir/ritonavir-containing regimen: an index of atherogenicity?
Hypertriglyceridemia
Dyslipidemia in a Cohort of HIV-infected Latin American Children Receiving Highly Active Antiretroviral Therapy.
Hypertriglyceridemia
Dyslipidemia, Diet and Physical Exercise in Children on Treatment With Antiretroviral Medication in El Salvador: A Cross-sectional Study.
Hypertriglyceridemia
Echocardiography and carotid intima-media thickness among asymptomatic HIV-infected adolescents in Thailand.
Hypertriglyceridemia
Endocrine and metabolic evaluation of human immunodeficiency virus-infected patients with evidence of protease inhibitor-associated lipodystrophy.
Hypertriglyceridemia
Gemfibrozil effectively lowers protease inhibitor-associated hypertriglyceridemia in HIV-1-positive patients.
Hypertriglyceridemia
Globin digest, acidic protease hydrolysate, inhibits dietary hypertriglyceridemia and Val-Val-Tyr-Pro, one of its constituents, possesses most superior effect.
Hypertriglyceridemia
H-risk dysmetabolism disorders associated with HAART-treated HIV disease, and reimbursement of lipid-lowering drugs, in a clinical and a socio-economic perspective.
Hypertriglyceridemia
HIV protease inhibitors promote atherosclerotic lesion formation independent of dyslipidemia by increasing CD36-dependent cholesteryl ester accumulation in macrophages.
Hypertriglyceridemia
Hyperlipidaemia a risk factor for femoral head osteonecrosis (Legg-Calv -Perthes-like disease) in children with AIDS: case report.
Hypertriglyceridemia
Hypertension, dyslipidemia and cardiovascular risk in HIV infected adults in Poland.
Hypertriglyceridemia
Hypertriglyceridemia and hypercholesterolemia in human immunodeficiency virus-1-infected children treated with protease inhibitors.
Hypertriglyceridemia
Impact of protease inhibitor substitution with efavirenz in HIV-infected children: results of the First Pediatric Switch Study.
Hypertriglyceridemia
Lipemia retinalis as a presenting feature of hypertriglyceridemia associated with protease inhibitors in human immunodeficiency virus-infected patients.
Hypertriglyceridemia
Lipid profile and renal safety of tenofovir disoproxil fumarate-based anti-retroviral therapy in HIV-infected Chinese patients.
Hypertriglyceridemia
Lipid profile of HIV-infected patients in relation to antiretroviral therapy: a review.
Hypertriglyceridemia
Lipodystrophy is an independent predictor of hypertriglyceridemia during pregnancy in HIV-infected women.
Hypertriglyceridemia
Plasmapheresis in the treatment of an acute pancreatitis due to protease inhibitor-induced hypertriglyceridemia.
Hypertriglyceridemia
Prevalence of renal disease within an urban HIV-infected cohort in northern Italy.
Hypertriglyceridemia
The beta-chemokines MIP-1alpha and RANTES and lipoprotein metabolism in HIV-infected Brazilian patients.
Hypertriglyceridemia
Use of fenofibrate in the management of protease inhibitor-associated lipid abnormalities.
Hypertriglyceridemia
Use of fibrates in the management of hyperlipidemia in HIV-infected patients receiving HAART.
Hypertriglyceridemia
Viral load of the human immunodeficiency virus could be an independent risk factor for endothelial dysfunction.
Hypertriglyceridemia
Visceral obesity, hypertriglyceridemia and hypercortisolism in a boy with perinatally acquired HIV infection receiving protease inhibitor-containing antiviral treatment.
Hypertriglyceridemia
[Efectiveness and safety of switching to raltegravir-based regimen in dyslipidemic HIV-infected patients receiving antiretroviral therapy at Arriaran Foundation].
Hypertriglyceridemia
[Protease inhibitor-associated hypertriglyceridemia and diabetes mellitus in HIV-infected patients]
Hypocalcemia
The role of calcium-sensing receptor signaling in regulating transepithelial calcium transport.
Hypoglycemia
Hypoglycemia enhances the expression of mRNA encoding beta-amyloid precursor protein in rat primary cortical astroglial cells.
Hypoglycemia
[Parameters of energy and nitrogen metabolism in rats under insulin-induced hypoglycemia]
Hypogonadism
Hypogonadotropic hypogonadism in human immunodeficiency virus-infected men: uncommonly low testosterone levels.
Hypogonadism
Novel mutations in testis-specific ubiquitin protease 26 gene may cause male infertility and hypogonadism.
Hypohidrosis
A novel mutation in ST14 at a functionally significant amino acid residue expands the spectrum of ichthyosis-hypotrichosis syndrome.
Hypoparathyroidism
The role of calcium-sensing receptor signaling in regulating transepithelial calcium transport.
Hypophosphatemia, Familial
Bone mineral density decline according to renal tubular dysfunction and phosphaturia in tenofovir-exposed HIV-infected patients.
Hypoprothrombinemias
Identification and three-dimensional structural analysis of nine novel mutations in patients with prothrombin deficiency.
Hypotension
Acute blood pressure effects of selected serine proteases in normotensive rats and dogs.
Hypotension
Effect of a new synthetic protease inhibitor on beta-endorphin release during acute pancreatitis in dogs.
Hypotension
Effects of losartan on blood pressure and humoral factors in a patient who suffered from anaphylactoid reactions when treated with ACE inhibitors during LDL apheresis.
Hypotension
Further evidence of bradykinin involvement in septic shock: reduction of kinin production in vivo and improved survival in rats by use of polymer tailored SBTI with longer t1/2.
Hypotension
Pancreatic Digestive Enzyme Blockade in the Small Intestine Prevents Insulin Resistance in Hemorrhagic Shock.
Hypotension
Pancreatic protease inhibition during shock attenuates cell activation and peripheral inflammation.
Hypotension
Protease-activated receptor 2-mediated vasodilatation in humans in vivo: role of nitric oxide and prostanoids.
Hypothyroidism
Hormonal regulation of epidermal growth factor and protease in the submandibular gland of the adult mouse.
Hypothyroidism
Multiple epidural steroid injections and body mass index linked with occurrence of epidural lipomatosis: a case series.
Hypothyroidism
Possible participation of colloid antigen 2 and abhormone (IgG with hormone activity) for the etiology of Graves' disease.
Hypothyroidism
Protease inhibitor-associated bone mineral density loss is related to hypothyroidism and related bone turnover acceleration.
Hypothyroidism
Protease inhibitors in sera as possible indicators of familial hypothyroidism.
Hypothyroidism
Reversible effects of cessation and recommencement of thyroxine treatment on insulin-like growth factors (IGFs) and IGF-binding proteins in patients with total thyroidectomy.
Hypotrichosis
A novel mutation in ST14 at a functionally significant amino acid residue expands the spectrum of ichthyosis-hypotrichosis syndrome.
Hypotrichosis
Autosomal ichthyosis with hypotrichosis syndrome displays low matriptase proteolytic activity and is phenocopied in ST14 hypomorphic mice.
Hypotrichosis
Autosomal recessive ichthyosis with hypotrichosis syndrome: further delineation of the phenotype.
Hypotrichosis
Mutation G827R in Matriptase Causing Autosomal Recessive Ichthyosis with Hypotrichosis Yields an Inactive Protease.
Ichthyosis
A novel mutation in ST14 at a functionally significant amino acid residue expands the spectrum of ichthyosis-hypotrichosis syndrome.
Ichthyosis
Acral Peeling Skin Syndrome Resulting from a Homozygous Nonsense Mutation in the CSTA Gene Encoding Cystatin A.
Ichthyosis
Autosomal ichthyosis with hypotrichosis syndrome displays low matriptase proteolytic activity and is phenocopied in ST14 hypomorphic mice.
Ichthyosis
Autosomal recessive ichthyosis with hypotrichosis syndrome: further delineation of the phenotype.
Ichthyosis
Cathelicidin represents a new target for manipulation of skin inflammation in Netherton syndrome.
Ichthyosis
Cystatin M/E knockdown by lentiviral delivery of shRNA impairs epidermal morphogenesis of human skin equivalents.
Ichthyosis
Cytotoxic effects of protease inhibitors on human cells. 1. High sensitivity of xeroderma pigmentosum cells to antipain.
Ichthyosis
Genotype-Phenotype Correlations Emerging from the Identification of Missense Mutations in MBTPS2.
Ichthyosis
Mutation G827R in Matriptase Causing Autosomal Recessive Ichthyosis with Hypotrichosis Yields an Inactive Protease.
Ichthyosis
Mutations in CSTA, encoding Cystatin A, underlie exfoliative ichthyosis and reveal a role for this protease inhibitor in cell-cell adhesion.
Ichthyosis, Lamellar
Harlequin ichthyosis: ABCA12 mutations underlie defective lipid transport, reduced protease regulation and skin-barrier dysfunction.
Idiopathic Pulmonary Fibrosis
Annexin A2 contributes to lung injury and fibrosis by augmenting factor Xa fibrogenic activity.
Idiopathic Pulmonary Fibrosis
Fibroblast activation protein: a serine protease expressed at the remodeling interface in idiopathic pulmonary fibrosis.
Idiopathic Pulmonary Fibrosis
Increased expression of protease nexin-1 in fibroblasts during idiopathic pulmonary fibrosis regulates thrombin activity and fibronectin expression.
Idiopathic Pulmonary Fibrosis
Loss of cells expressing fibroblast activation protein has variable effects in models of TGF-? and chronic bleomycin-induced fibrosis.
Idiopathic Pulmonary Fibrosis
Non-invasive Imaging of Idiopathic Pulmonary Fibrosis Using Cathepsin Protease Probes.
Idiopathic Pulmonary Fibrosis
Protease activated receptor-1 regulates macrophage-mediated cellular senescence: a risk for idiopathic pulmonary fibrosis.
Idiopathic Pulmonary Fibrosis
The fibrogenic actions of lung fibroblast-derived urokinase: a potential drug target in IPF.
Ileitis
Lactocepin secreted by Lactobacillus exerts anti-inflammatory effects by selectively degrading proinflammatory chemokines.
Immune Complex Diseases
A viral infection explanation for Kawasaki disease in general and for COVID-19 virus-related Kawasaki disease symptoms.
Immune Complex Diseases
An explanation of the pathogenesis of several autoimmune diseases in immuno-compromised individuals.
Immune Reconstitution Inflammatory Syndrome
(B3) Markers of immunodeficiency and mechanisms of HAART therapy on oral lesions.
Immune Reconstitution Inflammatory Syndrome
Herpes zoster as an immune restoration disease in AIDS patients during therapy including protease inhibitors.
Immune Reconstitution Inflammatory Syndrome
How best to approach endocrine evaluation in patients with HIV in the era of combined antiretroviral therapy?
Immune System Diseases
Sequence-Specific Alterations of Epitope Production by HIV Protease Inhibitors.
Impetigo
Plakoglobin rescues adhesive defects induced by ectodomain truncation of the desmosomal cadherin desmoglein 1: implications for exfoliative toxin-mediated skin blistering.
Infant, Newborn, Diseases
Correlation between the production of extracellular substances by type III group B streptococcal strains and virulence in a mouse model.
Infarction, Middle Cerebral Artery
Dipeptidyl peptidase IV, aminopeptidase N and DPIV/APN-like proteases in cerebral ischemia.
Infarction, Middle Cerebral Artery
Expression of myelencephalon-specific protease in transient middle cerebral artery occlusion model of rat brain.
Infarction, Middle Cerebral Artery
Stroke-induced subventricular zone proliferation is promoted by tumor necrosis factor-alpha-converting enzyme protease activity.
Infarction, Middle Cerebral Artery
Suppression of ischaemia-induced injuries in rat brain by protease-activated receptor-1 (PAR-1) activating peptide.
Infarction, Middle Cerebral Artery
The kunitz protease inhibitor domain of protease nexin-2 inhibits factor XIa and murine carotid artery and middle cerebral artery thrombosis.
Infections
?-Secretase promotes membrane insertion of the human papillomavirus L2 capsid protein during virus infection.
Infections
A 120-kDa alkaline peptidase from Trypanosoma cruzi is involved in the generation of a novel Ca(2+)-signaling factor for mammalian cells.
Infections
A 54 kDa cysteine protease purified from the crude extract of Neodiplostomum seoulense adult worms.
Infections
A beta1,3-glucan recognition protein from an insect, Manduca sexta, agglutinates microorganisms and activates the phenoloxidase cascade.
Infections
A blood fluke serine protease inhibitor regulates an endogenous larval elastase.
Infections
A chimeric virus-mouse model system for evaluating the function and inhibition of papain-like proteases of emerging coronaviruses.
Infections
A clinical isolate of dengue virus and its proteins induce apoptosis in HMEC-1 cells: a possible implication in pathogenesis.
Infections
A comprehensive review on promising anti-viral therapeutic candidates identified against main protease from SARS-CoV-2 through various computational methods.
Infections
A controlled trial of two nucleoside analogues plus indinavir in persons with human immunodeficiency virus infection and CD4 cell counts of 200 per cubic millimeter or less. AIDS Clinical Trials Group 320 Study Team.
Infections
A cost utility analysis of simeprevir used with peginterferon?+?ribavirin in the management of genotype 1 hepatitis C virus infection, from the perspective of the UK National Health Service.
Infections
A dual fluorescent/MALDI chip platform for analyzing enzymatic activity and for protein profiling.
Infections
A functional ubiquitin-specific protease embedded in the large tegument protein (ORF64) of murine gammaherpesvirus 68 is active during the course of infection.
Infections
A gammaherpesvirus ubiquitin-specific protease is involved in the establishment of murine gammaherpesvirus 68 infection.
Infections
A genome-wide CRISPR screen identifies N-acetylglucosamine-1-phosphate transferase as a potential antiviral target for Ebola virus.
Infections
A Hepatitis C Virus-Associated Chronic Hepatitis Patient Developing Various Adverse Events Including Severe Gingivitis, Gingival Bleeding, and Inflammation of Genital Vulva during the Course of Antiviral Therapy with Elbasvir/Grazoprevir.
Infections
A kinetic analysis of the expression of mast cell protease mRNA in the intestines of Nippostrongylus brasiliensis-infected rats.
Infections
A Lead-In with Silibinin Prior to Triple-Therapy Translates into Favorable Treatment Outcomes in Difficult-To-Treat HIV/Hepatitis C Coinfected Patients.
Infections
A metalloprotease secreted by the insect pathogen Photorhabdus luminescens induces melanization.
Infections
A model-based comparative meta-analysis of the efficacy of dolutegravir-based and efavirenz-based regimens in HIV-infected patients.
Infections
A molecular insight into algal-oomycete warfare: cDNA analysis of Ectocarpus siliculosus infected with the basal oomycete Eurychasma dicksonii.
Infections
A Molecular Sensor To Characterize Arenavirus Envelope Glycoprotein Cleavage by Subtilisin Kexin Isozyme 1/Site 1 Protease.
Infections
A monoclonal antibody against hinge-cleaved IgG restores effector function to proteolytically-inactivated IgGs in vitro and in vivo.
Infections
A mutation in human immunodeficiency virus type 1 protease, N88S, that causes in vitro hypersensitivity to amprenavir.
Infections
A neutralizing epitope of human immunodeficiency virus type 1 has homologous amino acid sequences with the active site of inter-alpha-trypsin inhibitor.
Infections
A new factor in the Aedes aegypti immune response: CLSP2 modulates melanization.
Infections
A new reporter cell line to monitor HIV infection and drug susceptibility in vitro.
Infections
A novel dual luciferase assay for the simultaneous monitoring of HIV infection and cell viability.
Infections
A novel serine protease inhibitor acts as an immunomodulatory switch while maintaining homeostasis.
Infections
A phase I/II study of the protease inhibitor ritonavir in children with human immunodeficiency virus infection.
Infections
A pilot-scale expressed sequence tag analysis of Beauveria bassiana gene expression reveals a tripeptidyl peptidase that is differentially expressed in vivo.
Infections
A population-based approach to determine the prevalence of transmitted drug-resistant HIV among recent versus established HIV infections: results from the Canadian HIV strain and drug resistance surveillance program.
Infections
A practical guide for the use of boceprevir and telaprevir for the treatment of hepatitis C.
Infections
A Proposal for a Structural Model of the Feline Calicivirus Protease Bound to the Substrate Peptide under Physiological Conditions.
Infections
A protease activation mutant, MVCES1, as a safe and potent live vaccine derived from currently prevailing Sendai virus.
Infections
A Protease Inhibitor with Induction Therapy with Natural Interferon-? in Patients with HCV Genotype 1b Infection.
Infections
A protein secreted in vivo by Echinococcus granulosus inhibits elastase activity and neutrophil chemotaxis.
Infections
A Randomized Open-Label Study of Three- versus Five-Drug Combination Antiretroviral Therapy in Newly HIV-1 Infected Individuals.
Infections
A randomized trial of daclatasvir with peginterferon alfa-2b and ribavirin for HCV genotype 1 infection.
Infections
A role for apical membrane antigen 1 during invasion of hepatocytes by Plasmodium falciparum sporozoites.
Infections
A role in immunity for Arabidopsis cysteine protease RD21, the ortholog of the tomato immune protease C14.
Infections
A rugged and accurate liquid chromatography-tandem mass spectrometry method for the determination of asunaprevir, an NS3 protease inhibitor, in plasma.
Infections
A Second Kazal-like protease inhibitor from Phytophthora infestans inhibits and interacts with the apoplastic pathogenesis-related protease P69B of tomato.
Infections
A secretory leukocyte protease inhibitor variant with improved activity against lung infection.
Infections
A Serine Protease Homolog Negatively Regulates TEP1 Consumption in Systemic Infections of the Malaria Vector Anopheles gambiae.
Infections
A signaling protease required for melanization in Drosophila affects resistance and tolerance of infections.
Infections
A small percentage of patients with hepatitis C receive triple therapy with boceprevir or telaprevir.
Infections
A study of cutaneous lesions caused by Leishmania mexicana in plasminogen-deficient mice.
Infections
A toggle switch controls the low pH-triggered rearrangement and maturation of the dengue virus envelope proteins.
Infections
A type III effector protease NleC from enteropathogenic Escherichia coli targets NF-?B for degradation.
Infections
ABT-450/r-Ombitasvir and Dasabuvir with Ribavirin for Hepatitis C with Cirrhosis.
Infections
Accelerated wound healing and its promoting effects of biomimetic collagen matrices with siderophore loaded gelatin microspheres in tissue engineering.
Infections
ACE2 and TMPRSS2 expression by clinical, HLA, immune, and microbial correlates across 34 human cancers and matched normal tissues: implications for SARS-CoV-2 COVID-19.
Infections
Acid protease activity of a major surface membrane glycoprotein (gp63) from Leishmania mexicana promastigotes.
Infections
Activation of Drosophila Toll during fungal infection by a blood serine protease.
Infections
Activation of plasminogen activator inhibitor implicates protease InhA in the acute-phase response to Bacillus anthracis infection.
Infections
Activation of the extrinsic caspase pathway in cultured cortical neurons requires p53-mediated down-regulation of the X-linked inhibitor of apoptosis protein to induce apoptosis.
Infections
Activation of the SARS coronavirus spike protein via sequential proteolytic cleavage at two distinct sites.
Infections
Active and passive intranasal immunizations with streptococcal surface protein C5a peptidase prevent infection of murine nasal mucosa-associated lymphoid tissue, a functional homologue of human tonsils.
Infections
Activities of the human immunodeficiency virus type 1 (HIV-1) protease inhibitor nelfinavir mesylate in combination with reverse transcriptase and protease inhibitors against acute HIV-1 infection in vitro.
Infections
Acute cellular uptake of abnormal prion protein is cell type and scrapie-strain independent.
Infections
Acute pancreatitis associated with different combination therapies in patients infected with human immunodeficiency virus.
Infections
Adjunct antibody administration with standard treatment reduces relapse rates in a murine tuberculosis model of necrotic granulomas.
Infections
Adrenal Enzyme Impairment in Neonates and Adolescents Treated with Ritonavir and Protease Inhibitors for HIV Exposure or Infection.
Infections
Advanced Glycation End Products Inhibit Both Infection and Transmission In Trans of HIV-1 from Monocyte-Derived Dendritic Cells to Autologous T Cells.
Infections
Adverse effects of antiretroviral drugs on HIV-1-infected and -uninfected human monocyte-derived macrophages.
Infections
Aerosol treatment with MNEI suppresses bacterial proliferation in a model of chronic Pseudomonas aeruginosa lung infection.
Infections
African swine fever virus IAP homologue inhibits caspase activation and promotes cell survival in mammalian cells.
Infections
Age-dependent changes in protease and elastase production in cultures of Pseudomonas aeruginosa.
Infections
Agreement between an in-house replication competent and a reference replication defective recombinant virus assay for measuring phenotypic resistance to HIV-1 protease, reverse transcriptase, and integrase inhibitors.
Infections
Aichi virus 3C protease modulates LC3- and SQSTM1/p62-involved antiviral response.
Infections
Airway protease/antiprotease imbalance in atopic asthmatics contributes to increased Influenza A virus cleavage and replication.
Infections
Alert to US physicians: DHEA, widely used as an OTC androgen supplement, may exacerbate COVID-19.
Infections
Alginate/Chitosan Particle-Based Drug Delivery Systems for Pulmonary Applications.
Infections
All-oral daclatasvir plus asunaprevir for hepatitis C virus genotype 1b: a multinational, phase 3, multicohort study.
Infections
Alpha-1 Antitrypsin for COVID-19 Treatment: Dual Role in Antiviral Infection and Anti-Inflammation.
Infections
Alphavirus capsid protease inhibitors as potential antiviral agents for Chikungunya infection.
Infections
Alterations in mast cell proteinases and protease inhibitors in the progress of cutaneous herpes zoster infection.
Infections
Altered budding site of a pantropic mutant of Sendai virus, F1-R, in polarized epithelial cells.
Infections
Altered expression of mast cell proteases in the rat. Quantitative and immunohistochemical analysis of the distribution of rat mast cell proteases I and II during helminth infection.
Infections
Altered gastric corpus expression of tissue inhibitors of metalloproteinases in human and murine Helicobacter infection.
Infections
Altered myocellular and abdominal fat partitioning predict disturbance in insulin action in HIV protease inhibitor-related lipodystrophy.
Infections
Alternaria alternata Accelerates Loss of Alveolar Macrophages and Promotes Lethal Influenza A Infection.
Infections
Amebocyte production begins at stage 18 during embryogenesis in Limulus polyphemus, the American horseshoe crab.
Infections
Amprenavir inhibitory quotient and virological response in human immunodeficiency virus-infected patients on an amprenavir-containing salvage regimen without or with ritonavir.
Infections
An earthworm protease cleaving serum fibronectin and decreasing HBeAg in HepG2.2.15 cells.
Infections
An effector caspase Sp-caspase first identified in mud crab Scylla paramamosain exhibiting immune response and cell apoptosis.
Infections
An Efficient Power Harvesting Mobile Phone-Based Electrochemical Biosensor for Point-of-Care Health Monitoring.
Infections
An explanation of the pathogenesis of several autoimmune diseases in immuno-compromised individuals.
Infections
An extracellular protease from Brevibacillus laterosporus G4 without parasporal crystals can serve as a pathogenic factor in infection of nematodes.
Infections
An immunogenic cathepsin F secreted by the parasitic stages of Teladorsagia circumcincta.
Infections
An in silico pharmacological approach toward the discovery of potent inhibitors to combat drug resistance HIV-1 protease variants.
Infections
An in-vitro evaluation of the efficacy of garlic extract as an antimicrobial agent on periodontal pathogens: A microbiological study.
Infections
An inhibitor of the protease blocks maturation of human and simian immunodeficiency viruses and spread of infection.
Infections
An OPTIMIZE Study Retrospective Analysis for the Management of Telaprevir-Treated HCV Patients Using the Abbott RealTime HCV RNA Assay.
Infections
An ShK-domain serine protease of Eriocheir sinensis regulates the PO activity to resist Spiroplasma eriocheiris infection.
Infections
An update on the toxicological considerations for protease inhibitors used for hepatitis C infection.
Infections
Analysis of HIV-1 protease gene reveals frequent multiple infections followed by recombination among drug treated individuals living in São Paulo and Santos, Brazil.
Infections
Analysis of prevalence of HIV-1 drug resistance in primary infections in the United Kingdom.
Infections
Analysis of protease activity in Aspergillus flavus and A. parasiticus on peanut seed infection and aflatoxin contamination
Infections
Analysis of secretory leukocyte protease inhibitor (SLPI) in bronchial secretions from patients with hypersecretory respiratory diseases.
Infections
Anatomic dissociation between HIV-1 and its endogenous inhibitor in mucosal tissues.
Infections
Anthrax lethal toxin has direct and potent inhibitory effects on B cell proliferation and immunoglobulin production.
Infections
Anti-human immunodeficiency virus type 1 activities of U-90152 and U-75875 in human brain cell cultures.
Infections
Anti-Retroviral Protease Inhibitors Regulate Human Papillomavirus 16 Infection of Primary Oral and Cervical Epithelium.
Infections
Antibacterial activity and genotypic-phenotypic characteristics of bacteriocin-producing Bacillus subtilis KKU213: potential as a probiotic strain.
Infections
Antibacterial activity of the human host defence peptide LL-37 and selected synthetic cationic lipids against bacteria associated with oral and upper respiratory tract infections.
Infections
Antibody Responses against Enterovirus Proteases are Potential Markers for an Acute Infection.
Infections
Antigen detection and apoptosis in Mongolian gerbil's kidney experimentally intraperitoneally infected by swine hepatitis E virus.
Infections
Antigenic reactivity of the major glycoprotein of equine infectious anemia virus, a retrovirus.
Infections
Antigenicity of a filarial protease from Setaria digitata in Wuchereria bancrofti infection.
Infections
Antileukoprotease in human skin: an antibiotic peptide constitutively produced by keratinocytes.
Infections
Antimicrobial activity and stability of the D-amino acid substituted derivatives of antimicrobial peptide polybia-MPI.
Infections
Antimicrobial peptides of the vaginal innate immunity and their role in the fight against sexually transmitted diseases.
Infections
Antiretroviral Salvage Therapy for Multiclass Drug-Resistant HIV-1-Infected Patients: From Clinical Trials to Daily Clinical Practice.
Infections
Antiretroviral therapy based on protease inhibitors as a protective factor against liver fibrosis progression in patients with chronic hepatitis C.
Infections
Antiviral activity and mode of action of TMC647078, a novel nucleoside inhibitor of the hepatitis C virus NS5B polymerase.
Infections
Antiviral activity of human immunodeficiency virus type 1 protease inhibitors in a single cycle of infection: evidence for a role of protease in the early phase.
Infections
Antiviral activity of trappin-2 and elafin in vitro and in vivo against genital herpes.
Infections
Antiviral Chemistry & Chemotherapy's current antiviral agents FactFile (2nd edition): retroviruses and hepadnaviruses.
Infections
Antiviral Chemistry & Chemotherapy's current antiviral agents FactFile 2008 (2nd edition): RNA viruses.
Infections
Antiviral efficacy of NS3-serine protease inhibitor BILN-2061 in patients with chronic genotype 2 and 3 hepatitis C.
Infections
Antiviral lectins from red and blue-green algae show potent in vitro and in vivo activity against hepatitis C virus.
Infections
Antiviral resistance and the future landscape of hepatitis C virus infection therapy.
Infections
Antiviral treatment of hepatitis C virus infection and factors affecting efficacy.
Infections
Apocynin and ebselen reduce influenza A virus-induced lung inflammation in cigarette smoke-exposed mice.
Infections
Apoptosis induced by HIV infection in H9 T cells is blocked by ICE-family protease inhibition but not by a Fas(CD95) antagonist.
Infections
Apoptotic suppression by baculovirus P35 involves cleavage by and inhibition of a virus-induced CED-3/ICE-like protease.
Infections
Apparent interaction between telaprevir and warfarin in a patient with chronic hepatitis C viral infection.
Infections
Appearance of protease activities coincides with p10 and polyhedrin-driven protein production in the baculovirus expression system: effects on yield.
Infections
Application of a cell-based protease assay for testing inhibitors of picornavirus 3C proteases.
Infections
Are the cutaneous manifestations during or due to SARS-CoV-2 infection/COVID-19 frequent or not? Revision of possible pathophysiologic mechanisms.
Infections
Asc Modulates the Function of NLRC4 in Response to Infection of Macrophages by Legionella pneumophila.
Infections
Aspartic protease inhibitors as potential anti-Candida albicans drugs: impacts on fungal biology, virulence and pathogenesis.
Infections
Assembly and selective "in synthesis" labeling of quenched fluorogenic protease substrates.
Infections
Assessing the Contribution of an HtrA Family Serine Protease During Borrelia turicatae Mammalian Infection.
Infections
Assessment of FIV-C infection of cats as a function of treatment with the protease inhibitor, TL-3.
Infections
Assessment of protease (elastase) as a Pseudomonas aeruginosa virulence factor in experimental mouse burn infection.
Infections
Association of hypocholesterolaemia with hepatitis C virus infection in HIV-infected people.
Infections
Atherosclerosis and central adiposity in a pediatric patient with AIDS treated with HAART: autopsy findings.
Infections
Autophagy interferes with human cytomegalovirus genome replication, morphogenesis, and progeny release.
Infections
Bacillus sp. B16 kills nematodes with a serine protease identified as a pathogenic factor.
Infections
Bacteria- and IMD Pathway-Independent Immune Defenses against Plasmodium falciparum in Anopheles gambiae.
Infections
Bacterial vaginosis, not HIV, is primarily responsible for increased vaginal concentrations of proinflammatory cytokines.
Infections
Benzhydrylpiperazine compounds inhibit cholesterol-dependent cellular entry of hepatitis C virus.
Infections
Beyond telaprevir and boceprevir: resistance and new agents for hepatitis C virus infection.
Infections
Bezafibrate-induced improvement in glucose uptake and endothelial function in protease inhibitor-associated insulin resistance.
Infections
Bilateral uveitis associated with concurrent administration of rifabutin and nelfinavir.
Infections
Bile acid recognition by the Clostridium difficile germinant receptor, CspC, is important for establishing infection.
Infections
Bioengineering a humanized acne microenvironment model: proteomics analysis of host responses to Propionibacterium acnes infection in vivo.
Infections
Blocking phosphatidylcholine utilization in Pseudomonas aeruginosa, via mutagenesis of fatty acid, glycerol and choline degradation pathways, confirms the importance of this nutrient source in vivo.
Infections
Boceprevir: a novel nonstructural 3 (NS3) protease inhibitor for the treatment of chronic hepatitis C infection.
Infections
Boceprevir: A Protease Inhibitor for the Treatment of Chronic Hepatitis C (September).
Infections
Boceprevir: an oral protease inhibitor for the treatment of chronic HCV infection.
Infections
Bone metabolism in children with human immunodeficiency virus infection receiving highly active anti-retroviral therapy including a protease inhibitor.
Infections
Bovine viral diarrhea virus: prevention of persistent fetal infection by a combination of two mutations affecting Erns RNase and Npro protease.
Infections
Brain-Gut Interactions Increase Peripheral Nociceptive Signaling in Mice with Post-Infectious Irritable Bowel Syndrome.
Infections
Buccal cancer in a female patient with human immunodeficiency virus-2 infection.
Infections
CalA, a cyanobacterial AbrB protein, interacts with the upstream region of hypC and acts as a repressor of its transcription in the cyanobacterium Nostoc sp. strain PCC 7120.
Infections
Can SARS-CoV-2 infect the eye? An overview of the receptor status in ocular tissue.
Infections
Candida albicans OPI1 regulates filamentous growth and virulence in vaginal infections, but not inositol biosynthesis.
Infections
Canine Hepacivirus NS3 Serine Protease Can Cleave the Human Adaptor Proteins MAVS and TRIF.
Infections
Cardiorenal Tissues Express SARS-CoV-2 Entry Genes and Basigin (BSG/CD147) Increases With Age in Endothelial Cells.
Infections
Caspase-3 activation and ERK phosphorylation during CVB3 infection of cells: influence of the coxsackievirus and adenovirus receptor and engineered variants.
Infections
Catch-and-release probes applied to semi-intact cells reveal ubiquitin-specific protease expression in Chlamydia trachomatis infection.
Infections
Cathepsin B Protease Facilitates Chikungunya Virus Envelope Protein-Mediated Infection via Endocytosis or Macropinocytosis.
Infections
Cathepsin G, a neutrophil-derived serine protease, increases susceptibility of macrophages to acute human immunodeficiency virus type 1 infection.
Infections
CD4+ T cell count recovery in HIV type 1-infected patients is independent of class of antiretroviral therapy.
Infections
CD8(+) T-cell gamma interferon production specific for human immunodeficiency virus type 1 (HIV-1) in HIV-1-infected subjects.
Infections
CD8+ T lymphocyte responses target functionally important regions of Protease and Integrase in HIV-1 infected subjects.
Infections
Cell cycle arrest by Vpr in HIV-1 virions and insensitivity to antiretroviral agents.
Infections
Cellular inhibitors with Fv1-like activity restrict human and simian immunodeficiency virus tropism.
Infections
Challenges for Targeting SARS-CoV-2 Proteases as a Therapeutic Strategy for COVID-19.
Infections
Changes in hydrolytic enzyme activities of naïve Atlantic salmon Salmo salar skin mucus due to infection with the salmon louse Lepeophtheirus salmonis and cortisol implantation.
Infections
Changes in tonsillar tissue in early HIV-1 infection and during 3 years of antiretroviral therapy.
Infections
Characterization of a cell density-dependent sRNA, Qrr, and its roles in the regulation of the quorum sensing and metabolism in Vibrio alginolyticus.
Infections
Characterization of a persistent respiratory syncytial virus showing a low-fusogenic activity associated to an impaired F protein.
Infections
Characterization of an antigenic serine protease in the Trichinella spiralis adult.
Infections
Characterization of an extracellular protease and its cDNA from the nematode-trapping fungus Monacrosporium microscaphoides.
Infections
Characterization of rabbit corneal damage produced by Serratia keratitis and by a serratia protease.
Infections
Characterization of subtilase protease in Cryptosporidium parvum and C. hominis.
Infections
Characterization of the herpes simplex virus (HSV)-1 tegument protein VP1-2 during infection with the HSV temperature-sensitive mutant tsB7.
Infections
Characterization of Toxoplasma DegP, a rhoptry serine protease crucial for lethal infection in mice.
Infections
Characterizing the Pharmacokinetic Interaction Between Simeprevir and Odalasvir in Healthy Volunteers Using a Population Modeling Approach.
Infections
Chemical proteomic identification of T-plastin as a novel host cell response factor in HCV infection.
Infections
Chlamydia Protease-like Activity Factor (CPAF): Characterization of Proteolysis Activity in Vitro and Development of a Nanomolar Affinity CPAF Zymogen-Derived Inhibitor.
Infections
Chlamydia trachomatis mouse pneumonitis lung infection in IL-18 and IL-12 knockout mice: IL-12 is dominant over IL-18 for protective immunity.
Infections
Choice of antiretroviral therapy differentially impacts survival of HIV-infected CD4 T cells.
Infections
Cholesterol and host cell surface proteins contribute to cell-cell fusion induced by the Burkholderia type VI secretion system 5.
Infections
Cholesterol-based cationic liposome increases dsRNA protection of yellow head virus infection in Penaeus vannamei.
Infections
Chronic hereditary pancreatitis in a girl with a serine protease inhibitor kazal type I (SPINK-1) gene mutation and a coxsackie type B5 infection.
Infections
Chronic obstructive pulmonary disease: risk factors, pathophysiology and pathogenesis.
Infections
Cigarette Smoke Stimulates SARS-CoV-2 Internalization by Activating AhR and Increasing ACE2 Expression in Human Gingival Epithelial Cells.
Infections
Circulating levels and ex vivo production of beta-chemokines, interferon gamma, and interleukin 2 in advanced human immunodeficiency virus type 1 infection: the effect of protease inhibitor therapy.
Infections
Cirrhosis in hepatitis C virus-infected patients: a review for practitioners new to hepatitis C care.
Infections
Citrus Psorosis Virus Movement Protein Contains an Aspartic Protease Required for Autocleavage and the Formation of Tubule-Like Structures at Plasmodesmata.
Infections
Cleavage and Sub-Cellular Redistribution of Nuclear Pore Protein 98 by Coxsackievirus B3 Protease 2A Impairs Cardioprotection.
Infections
Cleavage of DAP5 by coxsackievirus B3 2A protease facilitates viral replication and enhances apoptosis by altering translation of IRES-containing genes.
Infections
Cleavage of protein prM is necessary for infection of BHK-21 cells by tick-borne encephalitis virus.
Infections
Cleavage of spike protein of SARS coronavirus by protease factor Xa is associated with viral infectivity.
Infections
Cleavage of the bovine herpesvirus glycoprotein B is not essential for its function.
Infections
Cleavage of the NF-{kappa}B-family protein p65/RelA by the chlamydial protease chlamydial protease-like activity factor (CPAF) impairs pro-inflammatory signalling in cells Infected with chlamydiae.
Infections
Clinical and immunologic response without decrease in virus load in patients with AIDS after 24 months of highly active antiretroviral therapy.
Infections
Clinical pharmacology profile of boceprevir, a hepatitis C virus NS3 protease inhibitor: focus on drug-drug interactions.
Infections
Clinical update: impact of HIV protease inhibitors on the treatment of HIV-infected tuberculosis patients with rifampin.
Infections
Cloning and expression of a novel serine protease from Japanese flounder, Paralichthys olivaceus.
Infections
Cloning of the gene Lecanicillium psalliotae chitinase Lpchi1 and identification of its potential role in the biocontrol of root-knot nematode Meloidogyne incognita.
Infections
Cloning, expression, and characterization of two novel cuticle-degrading serine proteases from the entomopathogenic fungus Cordyceps sinensis.
Infections
Co-administration of tenofovir plus protease inhibitor based antiretroviral therapy during sofosbuvir/ledipasvir treatment for HCV infection: Much Ado About Nothing?
Infections
Co-formulated elvitegravir, cobicistat, emtricitabine, and tenofovir disoproxil fumarate versus ritonavir-boosted atazanavir plus co-formulated emtricitabine and tenofovir disoproxil fumarate for initial treatment of HIV-1 infection: a randomised, double-blind, phase 3, non-inferiority trial.
Infections
Co?expression of peripheral olfactory receptors with SARS?CoV?2 infection mediators: Potential implications beyond loss of smell as a COVID?19 symptom.
Infections
Coagulation, fibrinolysis, and kallikrein systems in sepsis: relation to outcome.
Infections
Cognitive decline with immunologic and virologic stability in four children with human immunodeficiency virus disease.
Infections
Combination and tricombination therapy to destabilize the structural integrity of COVID-19 by some bioactive compounds with antiviral drugs: insights from molecular docking study.
Infections
Combination antiretroviral therapy and cell-cell spread of wild-type and drug-resistant human immunodeficiency virus-1.
Infections
Combination of Antifungal Drugs and Protease Inhibitors Prevent Candida albicans Biofilm Formation and Disrupt Mature Biofilms.
Infections
Combination therapy for patients with HIV-1 infection: the use of dual nucleoside analogues with protease inhibitors and other agents.
Infections
Combined effect of zidovudine (ZDV), lamivudine (3TC) and abacavir (ABC) antiretroviral therapy in suppressing in vitro FIV replication.
Infections
Combined therapy of a cephalosporin, Shiomarin and a new potent protease inhibitor, E3123 in rat taurocholate-induced pancreatitis.
Infections
Common genetic variation in humans impacts in vitro susceptibility to SARS-CoV-2 infection.
Infections
Common Genetic Variation in Humans Impacts In Vitro Susceptibility to SARS-CoV-2 Infection.
Infections
Comparative analyses of ACE2 and TMPRSS2 gene: Implications for the risk to which vertebrate animals are susceptible to SARS-CoV-2.
Infections
Comparative cost-efficacy analysis of darunavir/ritonavir and other ritonavir-boosted protease inhibitors for first-line treatment of HIV-1 infection in the United States.
Infections
Comparative proteomic analysis revealed complex responses to classical/novel duck reovirus infections in the spleen tissue of Cairna moschata.
Infections
Comparative Proteomic Analysis Reveals Complex Responses to Bordetella bronchiseptica Infections in the Spleen of Rabbits.
Infections
Comparative proteomic analysis reveals that caspase-1 and serine protease may be involved in silkworm resistance to Bombyx mori nuclear polyhedrosis virus.
Infections
Comparative studies of two-times-daily versus three-times-daily indinavir in combination with zidovudine and lamivudine.
Infections
Comparison between secretory leukocytic protease inhibitor and reactive nitrogen intermediates levels in cervicovaginal secretions from symptomatic and asymptomatic trichomoniasis Egyptians patients.
Infections
Comparison of HIV type 1 protease inhibitor susceptibility results in viral samples analyzed by phenotypic drug resistance assays and by six resistance algorithms: an analysis of a subpopulation of the CHORUS cohort.
Infections
Comparison of HIV-1 pol and env sequences of blood, CSF, brain and spleen isolates collected ante-mortem and post-mortem.
Infections
Comprehensive Identification and Characterization of Long Non-coding RNAs Associated With Rice Black-Streaked Dwarf Virus Infection in Laodelphax striatellus (Fallén) Midgut.
Infections
Conditional human immunodeficiency virus type 1 protease mutants show no role for the viral protease early in virus replication.
Infections
Conformational rearrangements required of the V3 loop of HIV-1 gp120 for proteolytic cleavage and infection.
Infections
Considerations in the choice of protease inhibitor-sparing regimens in initial therapy for HIV-1 infection.
Infections
Construction of a novel SHIV having an HIV-1-derived protease gene and its infection to rhesus macaques: a useful tool for in vivo efficacy tests of protease inhibitors.
Infections
Construction of hepatitis C-SIN virus recombinants with replicative dependency on hepatitis C virus serine protease activity.
Infections
Continuous regional arterial infusion (CRAI) therapy reduces the mortality rate of acute necrotizing pancreatitis: results of a cooperative survey in Japan.
Infections
Continuous Regional Arterial Infusion of Protease Inhibitors Has No Efficacy in the Treatment of Severe Acute Pancreatitis: A Retrospective Multicenter Cohort Study.
Infections
Contribution of antibody response to recombinant HIV-1 gene-encoded products nef, rev, tat, and protease in predicting development of AIDS in HIV-1-infected individuals.
Infections
Contribution of Aspartic Proteases in Candida Virulence. Protease Inhibitors against Candida Infections.
Infections
Contribution of YjbIH to Virulence Factor Expression and Host Colonization in Staphylococcus aureus.
Infections
Control of T Helper 2 Responses by Transcription Factor IRF4-Dependent Dendritic Cells.
Infections
Conversion of the HIV protease inhibitor nelfinavir to a bioactive metabolite by human liver CYP2C19.
Infections
Cooperative activation of TLR2 and bradykinin B2 receptor is required for induction of type 1 immunity in a mouse model of subcutaneous infection by Trypanosoma cruzi.
Infections
Correlation between SPINK5 Gene Mutations and Clinical Manifestations in Netherton Syndrome Patients.
Infections
Cost Effectiveness of Direct-Acting Antiviral Therapy for Treatment-Naive Patients With Chronic HCV Genotype 1 Infection in the Veterans Health Administration.
Infections
Cost-effectiveness analysis of boceprevir for the treatment of chronic hepatitis C virus genotype 1 infection in Portugal.
Infections
Cost-Effectiveness Analysis of Triple Therapy with Protease Inhibitors in Treatment-Naive Hepatitis C Patients.
Infections
Cost-Effectiveness and Population Outcomes of General Population Screening for Hepatitis C.
Infections
Cost-effectiveness of boceprevir in patients previously treated for chronic hepatitis C genotype 1 infection in the United States.
Infections
Cost-effectiveness of IL28? genotype-guided protease inhibitor triple therapy versus standard of care treatment in patients with hepatitis C genotypes 2 or 3 infection.
Infections
Cost-effectiveness of Oral Protease Inhibitors Co-administration versus Pegylated Interferon-?2b and Ribavirin Only for the Patients with Hepatitis C Genotype 1 in Kazakhstan Health Care Settings.
Infections
Cost-effectiveness of sofosbuvir for the treatment of chronic hepatitis C-infected patients.
Infections
Cost-effectiveness of telaprevir in patients with genotype 1 hepatitis C in Australia.
Infections
Could targeting secretory leukocyte protease inhibitor be an effective therapeutic option to prevent infections in acute liver failure?
Infections
CPAF selectively degrades chlamydial T cell antigens for inhibiting antigen presentation.
Infections
Crystallization, characterization and measurement of MAD data on crystals of dengue virus NS3 serine protease complexed with mung-bean Bowman-Birk inhibitor.
Infections
CspA regulation of Staphylococcus aureus carotenoid levels and ?B activity is controlled by YjbH and Spx.
Infections
Current and future therapies for hepatitis C virus infection: from viral proteins to host targets.
Infections
Cuticle-degrading proteases produced by the entomopathogenic fungus Beauveria bassiana in the presence of coffee berry borer cuticle.
Infections
Dabrafenib, idelalisib and nintedanib act as significant allosteric modulator for dengue NS3 protease.
Infections
Daclatasvir in combination with asunaprevir and beclabuvir for hepatitis C virus genotype 1 infection with compensated cirrhosis.
Infections
Darunavir/cobicistat for the treatment of HIV-1: a new era for compact drugs with high genetic barrier to resistance.
Infections
Darunavir/Cobicistat/Emtricitabine/Tenofovir Alafenamide: A Review in HIV-1 Infection.
Infections
Debio 025, a cyclophilin binding molecule, is highly efficient in clearing hepatitis C virus (HCV) replicon-containing cells when used alone or in combination with specifically targeted antiviral therapy for HCV (STAT-C) inhibitors.
Infections
Deciphering the Infectious Process of Colletotrichum lupini in Lupin through Transcriptomic and Proteomic Analysis.
Infections
Deciphering the intrinsic properties of fungal proteases in optimizing phytopathogenic interaction.
Infections
Decrease of HIV-1 RNA levels in lymphoid tissue and peripheral blood during treatment with ritonavir, lamivudine and zidovudine. Ritonavir/3TC/ZDV Study Group.
Infections
Degradation of protease inhibitors, immunoglobulins, and other serum proteins by Serratia protease and its toxicity to fibroblast in culture.
Infections
Deletion of Braun lipoprotein gene (lpp) and curing of plasmid pPCP1 dramatically alter the virulence of Yersinia pestis CO92 in a mouse model of pneumonic plague.
Infections
Deletion of the lon gene augments expression of Salmonella Pathogenicity Island (SPI)-1 and metal ion uptake genes leading to the accumulation of bactericidal hydroxyl radicals and host pro-inflammatory cytokine-mediated rapid intracellular clearance.
Infections
Deletion of the SNP1 trypsin protease from Stagonospora nodorum reveals another major protease expressed during infection.
Infections
Demonstration of the intracellular production of tissue-destructive protease by Legionella pneumophila multiplying within guinea-pig and human alveolar macrophages.
Infections
Dengue hemorrhagic fever-associated immunomediators induced via maturation of dengue virus nonstructural 4B protein in monocytes modulate endothelial cell adhesion molecules and human microvascular endothelial cells permeability.
Infections
Dengue virus NS2B protein targets cGAS for degradation and prevents mitochondrial DNA sensing during infection.
Infections
Dengue virus serotype 2 infection alters midgut and carcass gene expression in the Asian tiger mosquito, Aedes albopictus.
Infections
Dependence of nelfinavir brain uptake on dose and tissue concentrations of the selective P-glycoprotein inhibitor zosuquidar in rats.
Infections
Description of staphylococcus serine protease (ssp) operon in Staphylococcus aureus and nonpolar inactivation of sspA-encoded serine protease.
Infections
Design, activity, and 2.8 A crystal structure of a C2 symmetric inhibitor complexed to HIV-1 protease.
Infections
Design, synthesis and biological evaluation of heteroaryl diketohexenoic and diketobutanoic acids as HIV-1 integrase inhibitors endowed with antiretroviral activity.
Infections
Detection and quantification of dengue virus using a novel biosensor system based on dengue NS3 protease activity.
Infections
Detection of alpha 2-macroglobulin, alpha 1-protease inhibitor, and neutral protease-antiprotease complexes within liver granulomas of Schistosoma mansoni-infected mice.
Infections
Detection of low HCV viraemia by repeated HCV RNA testing predicts treatment failure to triple therapy with telaprevir.
Infections
Determinants of pantropism of the F1-R mutant of Sendai virus: specific mutations involved are in the F and M genes.
Infections
Determination of the cytotoxic effect of Clostridium histolyticum culture supernatant on HeLa cells in the presence of protease inhibitors.
Infections
Development of an Aeromonas hydrophila recombinant extracellular protease vaccine.
Infections
Development of an Aeromonas hydrophila? infection model using the protozoan Tetrahymena thermophila.
Infections
Development of boceprevir: a first-in-class direct antiviral treatment for chronic hepatitis C infection.
Infections
Development of cervical fat pads following therapy with human immunodeficiency virus type 1 protease inhibitors.
Infections
Development of cysteine protease inhibitors as chemotherapy for parasitic diseases: insights on safety, target validation, and mechanism of action.
Infections
Development of protease activation mutants of HVJ (Sendai virus) in persistently infected cell cultures.
Infections
Diagnosis of Corynebacterium pyogenes infection in pigs by immunodiffusion test with protease antigen.
Infections
Diagnosis of Fasciola gigantica infection using a monoclonal antibody-based sandwich ELISA for detection of circulating cathepsin B3 protease.
Infections
Diagnosis, prediction, and natural course of HIV-1 protease-inhibitor-associated lipodystrophy, hyperlipidaemia, and diabetes mellitus: a cohort study.
Infections
Dietary protease can alleviate negative effects of a coccidiosis infection on production performance in broiler chickens
Infections
Dietary vitamin C deficiency depressed the gill physical barriers and immune barriers referring to Nrf2, apoptosis, MLCK, NF-?B and TOR signaling in grass carp (Ctenopharyngodon idella) under infection of Flavobacterium columnare.
Infections
Differences in resistance mutations among HIV-1 non-subtype B infections: a systematic review of evidence (1996-2008).
Infections
Different kinetics of immunologic recovery using nelfinavir or lopinavir/ritonavir-based regimens in children with perinatal HIV-1 infection.
Infections
Differential bidirectional transfer of indinavir in the isolated perfused human placenta.
Infections
Differential Body Composition Effects of Protease Inhibitors Recommended for Initial Treatment of HIV Infection: A Randomized Clinical Trial.
Infections
Differential Efficacy of Protease Inhibitors Against HCV Genotypes 2a, 3a, 5a, and 6a NS3/4A Protease Recombinant Viruses.
Infections
Differential Exoproteome and Biochemical Characterisation of Neoparamoeba perurans.
Infections
Differential expression of Candida dubliniensis-secreted aspartyl proteinase genes (CdSAP1-4) under different physiological conditions and during infection of a keratinocyte culture.
Infections
Differential expression proteomics to investigate responses and resistance to Orobanche crenata in Medicago truncatula.
Infections
Differential gene expression in the pathogenic dermatophyte Arthroderma benhamiae in vitro versus during infection.
Infections
Differentially expressed genes in silkworm cell cultures in response to infection by Wolbachia and Cardinium endosymbionts.
Infections
Differentiation of acid-pH-dependent and -nondependent entry pathways for mouse hepatitis virus.
Infections
Diminished intracellular invariant chain expression after vaccinia virus infection.
Infections
Diminished representation of HIV-1 variants containing select drug resistance-conferring mutations in primary HIV-1 infection.
Infections
Direct derivation of human alveolospheres for SARS-CoV-2 infection modeling and drug screening.
Infections
Direct proteolytic cleavage of NLRP1B is necessary and sufficient for inflammasome activation by anthrax lethal factor.
Infections
Discovery of a non-peptidic inhibitor of west nile virus NS3 protease by high-throughput docking.
Infections
Discovery of new diketopiperazines inhibiting Burkholderia cenocepacia quorum sensing in vitro and in vivo.
Infections
Disorders of glucose metabolism in the context of human immunodeficiency virus infection.
Infections
Distinct effects of protease and reverse transcriptase inhibition in an immunological model of HIV-1 infection with impulsive drug effects.
Infections
DksA-HapR-RpoS axis regulates haemagglutinin protease production in Vibrio cholerae.
Infections
Duplication and transcriptional divergence of three Kunitz protease inhibitor genes that modulate insect and pathogen defenses in tea plant (Camellia sinensis).
Infections
Edwardsiella tarda-regulated proteins in Japanese flounder (Paralichthys olivaceus): Identification and evaluation of antibacterial potentials.
Infections
Effect of a bacterial pheromone peptide on host chemokine degradation in group A streptococcal necrotising soft-tissue infections.
Infections
Effect of a plant polyphenol-rich extract on the lung protease activities of influenza-virus-infected mice.
Infections
Effect of antiretroviral triple combinations including the protease inhibitor nelfinavir in heavily pretreated children with HIV-1 infection.
Infections
Effect of class-specific therapy interruption on persistence of HIV type 1 antiretroviral resistance.
Infections
Effect of human immunodeficiency virus-1 protease inhibitors on the clearance of human herpesvirus 8 from blood of human immunodeficiency virus-1-infected patients.
Infections
Effect of hydrogen peroxide and other protease inhibitors on Cryptosporidium parvum excystation and in vitro development.
Infections
Effect of internal cleavage site mutations in human immunodeficiency virus type 1 capsid protein on its structure and function.
Infections
Effect of Legionella pneumophila cytotoxic protease on human neutrophil and monocyte function.
Infections
Effectiveness and safety of daclatasvir plus asunaprevir for HCV genotype 1b patients aged 75 and over with or without cirrhosis.
Infections
Effectiveness and safety of first-generation protease inhibitors in real-world patients with hepatitis C virus genotype 1 infection in Brazil: a multicenter study.
Infections
Effectiveness of first-wave protease inhibitors in hepatitis C virus genotype 1 infection: a multicenter study in Brazil.
Infections
Effectiveness of protease inhibitor/nucleos(t)ide reverse transcriptase inhibitor-based second-line antiretroviral therapy for the treatment of HIV-1 infection in sub-Saharan Africa: systematic review and meta-analysis.
Infections
Effectiveness of switching from protease inhibitors to dolutegravir in combination with nucleoside reverse transcriptase inhibitors as maintenance antiretroviral therapy among HIV-positive patients.
Infections
Effectiveness of Telaprevir or Boceprevir in Treatment-experienced Patients with HCV Genotype 1 Infection and Cirrhosis.
Infections
Effects of an isogenic Zn-metalloprotease-deficient mutant of Legionella pneumophila in a guinea-pig pneumonia model.
Infections
Effects of elastase, protease and common antigen (OEP) from Pseudomonas aeruginosa on protection against burns in mice.
Infections
Effects of escin on indinavir crystallization time in the urine of patients with HIV-I infection: a multicenter, randomized, open-label, controlled, four-period crossover trial.
Infections
Effects of human immunodeficiency virus type 1 resistance to protease inhibitors on reverse transcriptase processing, activity, and drug sensitivity.
Infections
Effects of immunization of horses with common antigen (OEP), protease toxoid, and elastase toxoid on corneal ulceration due to Pseudomonas aeruginosa infection.
Infections
Effects of zinc sulfate on Pseudomonas aeruginosa infections and protease in rabbit corneas.
Infections
Efficacy and safety of atazanavir, with or without ritonavir, as part of once-daily highly active antiretroviral therapy regimens in antiretroviral-naive patients.
Infections
Efficacy and safety of atazanavir-based highly active antiretroviral therapy in patients with virologic suppression switched from a stable, boosted or unboosted protease inhibitor treatment regimen: the SWAN Study (AI424-097) 48-week results.
Infections
Efficacy and safety of atazanavir/ritonavir-based antiretroviral therapy for HIV-1 infected subjects: a systematic review and meta-analysis.
Infections
Efficacy and safety of switching to fixed-dose bictegravir, emtricitabine, and tenofovir alafenamide from boosted protease inhibitor-based regimens in virologically suppressed adults with HIV-1: 48 week results of a randomised, open-label, multicentre, phase 3, non-inferiority trial.
Infections
Efficacy of constant infusion of A-77003, an inhibitor of the human immunodeficiency virus type 1 (HIV-1) protease, in limiting acute HIV-1 infection in vitro.
Infections
Efficacy of serine protease inhibitors against Cryptosporidium parvum infection in a bovine fallopian tube epithelial cell culture system.
Infections
Efficacy of the protease inhibitor BI 201335, polymerase inhibitor BI 207127, and ribavirin in patients with chronic HCV infection.
Infections
Efficacy of the protease inhibitors tipranavir plus ritonavir in treatment-experienced patients: 24-week analysis from the RESIST-1 trial.
Infections
Efficacy of the TMPRSS2 inhibitor camostat mesilate in patients hospitalized with Covid-19-a double-blind randomized controlled trial.
Infections
Efficacy, safety and pharmacokinetics of atazanavir (200mg twice daily) plus raltegravir (400mg twice daily) dual regimen in the clinical setting.
Infections
Efficient suppression of minority drug-resistant HIV type 1 (HIV-1) variants present at primary HIV-1 infection by ritonavir-boosted protease inhibitor-containing antiretroviral therapy.
Infections
Either periplasmic tethering or protease resistance is sufficient to allow a SodC to protect Salmonella enterica serovar Typhimurium from phagocytic superoxide.
Infections
Eligibility and safety of the first interferon-free therapy against hepatitis C in a real-world setting.
Infections
Eligibility and safety of triple therapy for hepatitis C: lessons learned from the first experience in a real world setting.
Infections
Emtricitabine/Tenofovir Disoproxil Fumarate: In Combination with a Protease Inhibitor in HIV-1 Infection.
Infections
Endocrinologic and immunologic factors associated with recovery of growth in children with human immunodeficiency virus type 1 infection treated with protease inhibitors.
Infections
Energy metabolic disorder is a major risk factor in severe influenza virus infection: Proposals for new therapeutic options based on animal model experiments.
Infections
Engineered toxins "zymoxins" are activated by the HCV NS3 protease by removal of an inhibitory protein domain.
Infections
Enhanced effect of fluorescent whitening agent on peroral infection for recombinant baculovirus in the host Bombyx mori L.
Infections
Enhanced enteroviral infectivity via viral protease-mediated cleavage of Grb2-associated binder 1.
Infections
Enhanced function annotations for Drosophila serine proteases: a case study for systematic annotation of multi-member gene families.
Infections
Enhancement of experimental cutaneous leishmaniasis by Leishmania extract: identification of a disease-associated antibody specificity.
Infections
Entamoeba histolytica infection and secreted proteins proteolytically damage enteric neurons.
Infections
Enterococcus faecalis mammalian virulence-related factors exhibit potent pathogenicity in the Arabidopsis thaliana plant model.
Infections
Enterovirus D68 Protease 2Apro Targets TRAF3 To Subvert Host Innate Immune Responses.
Infections
Entry from the cell surface of severe acute respiratory syndrome coronavirus with cleaved S protein as revealed by pseudotype virus bearing cleaved S protein.
Infections
Eradication of human immunodeficiency virus type 1-infected cells by a combination of antimetabolic cytotoxic chemotherapy and antiviral chemotherapy in vitro: a pilot study.
Infections
EspC, an Autotransporter Protein Secreted by Enteropathogenic Escherichia coli, Causes Apoptosis and Necrosis through Caspase and Calpain Activation, Including Direct Procaspase-3 Cleavage.
Infections
Evaluating the role of atazanavir/cobicistat and darunavir/cobicistat fixed-dose combinations for the treatment of HIV-1 infection.
Infections
Evaluation of anti-influenza effects of camostat in mice infected with non-adapted human influenza viruses.
Infections
Evaluation of efficacy, pharmacokinetics and tolerability of peptidomimetic aspartic proteinase inhibitors as cream formulation in experimental vaginal candidiasis.
Infections
Evaluation of genotypic and phenotypic protease virulence tests for Dichelobacter nodosus infection in sheep.
Infections
Evaluation of immunoglobulin A1 (IgA1) protease and IgA1 protease-inhibitory activity in human female genital infection with Neisseria gonorrhoeae.
Infections
Evaluation of Intra and Extraepitheilal Secretory IgA (SIgA) in Chlamydial Infections.
Infections
Evaluation of multiple failure time analyses of observational data in patients treated for HIV.
Infections
Evaluation of the Antimicrobial Activity of an Extract of Lactobacillus casei-Infected Hermetia illucens Larvae Produced Using an Automatic Injection System.
Infections
Evaluation of the Pharmacokinetics and Renal Excretion of Simeprevir in Subjects with Renal Impairment.
Infections
Evidence for the ancient origin of the NF-{kappa}B/I{kappa}B cascade: Its archaic role in pathogen infection and immunity.
Infections
Evolutionary Pathways to Persistence of Highly Fit and Resistant Hepatitis C Virus Protease Inhibitor Escape Variants.
Infections
Experimental studies of the pathogenesis of infections due to Pseudomonas aeruginosa: effect of treatment with protease inhibitors.
Infections
Experimental studies of the pathogenesis of infections due to Pseudomonas aeruginosa: extracellular protease and elastase as in vivo virulence factors.
Infections
Experimental studies of the pathogenesis of infections owing to Pseudomonas aeruginosa: elastase, an IgG protease.
Infections
Exploring the efficacy of naturally occurring biflavone based antioxidants towards the inhibition of the SARS-CoV-2 spike glycoprotein mediated membrane fusion.
Infections
Expression dynamics of secreted protease genes in Trichophyton rubrum induced by key host's proteinaceous components.
Infections
Expression of a serine protease gene prC is up-regulated by oxidative stress in the fungus Clonostachys rosea: implications for fungal survival.
Infections
Expression of factor X and its significance for the determination of paramyxovirus tropism in the chick embryo.
Infections
Expression of gangliosides as receptors at the cell surface controls infection of NCTC 2071 cells by Sendai virus.
Infections
Expression of mast-cell-specific proteases in tissues of mice studied by in situ hybridization.
Infections
Expression of SARS-CoV-2 receptor ACE2 and the protease TMPRSS2 suggests susceptibility of the human embryo in the first trimester.
Infections
Expression of secretory leukocyte protease inhibitor and elafin in human fallopian tube and in an in-vitro model of Chlamydia trachomatis infection.
Infections
Expression of the NS3 protease of cytopathogenic BVDV results in the induction of apoptosis but does not block activation of the interferon beta promoter.
Infections
F0-containing noninfectious Sendai virus can initiate replication in mouse lungs but requires a relatively long incubation period.
Infections
Factors associated with statin selection among privately insured commercial and Medicare patients.
Infections
Factors that predict response of patients with hepatitis C virus infection to boceprevir.
Infections
Fasciola hepatica surface tegument: glycoproteins at the interface of parasite and host.
Infections
Fibrinogen cleavage by the Streptococcus pyogenes extracellular cysteine protease and generation of antibodies that inhibit enzyme proteolytic activity.
Infections
Fibrinolytic Serine Proteases, Therapeutic Serpins and Inflammation: Fire Dancers and Firestorms.
Infections
First investigation of the presence of SPATE genes in Shigella species isolated from children with diarrhea infection in Ahvaz, southwest Iran.
Infections
First line raltegravir/emtricitabine/tenofovir combination in HIV-2 infection: phase 2 non-comparative trial (ANRS 159 HIV-2).
Infections
First successful treatment of post-liver transplant hepatitis C fibrosing cholestatic hepatitis with boceprevir, peginterferon and ribavirin in a pre-transplant null responder.
Infections
From lysosomes to cells, from cells to Leishmania: amino acid esters as potential chemotherapeutic agents.
Infections
From transcription to activation: how group A streptococcus, the flesh-eating pathogen, regulates SpeB cysteine protease production.
Infections
Fullerene Derivatives Strongly Inhibit HIV-1 Replication by Affecting Virus Maturation without Impairing Protease Activity.
Infections
Functional and Evolutionary Analyses Identify Proteolysis as a General Mechanism for NLRP1 Inflammasome Activation.
Infections
Functional and therapeutic analysis of hepatitis C virus NS3.4A protease control of antiviral immune defense.
Infections
Functional attribution of LdISP, an endogenous serine protease inhibitor from Leishmania donovani in promoting infection.
Infections
Functional characterization of a serine protease inhibitor modulated in the infection of the Aedes aegypti with dengue virus.
Infections
Functional characterization of the protease of human endogenous retrovirus, K10: can it complement HIV-1 protease?
Infections
Functional diversification upon leader protease domain duplication in the Citrus tristeza virus genome: Role of RNA sequences and the encoded proteins.
Infections
Functional identification of the gene bace16 from nematophagous bacterium Bacillus nematocida.
Infections
Functions of surface glycoproteins of myxoviruses and paramyxoviruses and their inhibition.
Infections
Fungal effector protein AVR2 targets diversifying defense-related cys proteases of tomato.
Infections
Fusion-induced apoptosis contributes to thymocyte depletion by a pathogenic human immunodeficiency virus type 1 envelope in the human thymus.
Infections
Galectin-3 Is a Target for Proteases Involved in the Virulence of Staphylococcus aureus.
Infections
Gasdermin-D and Caspase-7 are the key Caspase-1/8 substrates downstream of the NAIP5/NLRC4 inflammasome required for restriction of Legionella pneumophila.
Infections
Gene expression in the chicken caecum in response to infections with non-typhoid Salmonella.
Infections
Genetic basis of hypersusceptibility to protease inhibitors and low replicative capacity of human immunodeficiency virus type 1 strains in primary infection.
Infections
Genetic variants of human granzyme B predict transplant outcomes after HLA matched unrelated bone marrow transplantation for myeloid malignancies.
Infections
Genome-wide association analysis for porcine reproductive and respiratory syndrome virus susceptibility traits in two genetic populations of pigs1.
Infections
Genome-wide identification of the Sec-dependent secretory protease genes in Erwinia amylovora and analysis of their expression during infection of immature pear fruit.
Infections
Genomic innovations linked to infection strategies across emerging pathogenic chytrid fungi.
Infections
Genotype differences in susceptibility and resistance development of hepatitis C virus to protease inhibitors telaprevir (VX-950) and danoprevir (ITMN-191).
Infections
Genotypes coding for low serum levels of mannose-binding lectin are underrepresented among individuals suffering from noninfectious systemic inflammatory response syndrome.
Infections
Gilbert's syndrome and hyperbilirubinemia in protease inhibitor therapy--an extended haplotype of genetic variants increases risk in indinavir treatment.
Infections
Good and bad molecular fingerprints for human rhinovirus 3C protease inhibition: identification, validation, and application in designing of new inhibitors through Monte Carlo-based QSAR study.
Infections
Grazoprevir, Elbasvir, and Ribavirin for Chronic Hepatitis C Virus Genotype 1 Infection After Failure of Pegylated Interferon and Ribavirin With an Earlier-Generation Protease Inhibitor: Final 24-Week Results From C-SALVAGE.
Infections
Group A Streptococcus Infection of the Nasopharynx Requires Proinflammatory Signaling through the Interleukin-1 Receptor.
Infections
Group A Streptococcus M1T1 Intracellular Infection of Primary Tonsil Epithelial Cells Dampens Levels of Secreted IL-8 Through the Action of SpyCEP.
Infections
Guidance for clinical trials for children and adolescents with chronic hepatitis C.
Infections
Hageman factor dependent activation and its relationship to lethal Pseudomonas aeruginosa burn wound infections.
Infections
Haploid Genetic Screen Reveals a Profound and Direct Dependence on Cholesterol for Hantavirus Membrane Fusion.
Infections
HCV genotype 1-6 NS3 residue 80 substitutions impact protease inhibitor activity and promote viral escape.
Infections
HCV NS3Ag: a reliable and clinically useful predictor of antiviral outcomes in genotype 1b hepatitis C virus-infected patients.
Infections
HCV viral load at baseline and at week 4 of telaprevir/boceprevir based triple therapies are associated with virological outcome in HIV/hepatitis C co-infected patients.
Infections
Heat shock cognate protein 70 gene is required for prevention of apoptosis induced by WSSV infection.
Infections
Helicobacter pylori infection and short-term intake of low-dose aspirin have different effects on alpha-1 antitrypsin/alpha-1 peptidase inhibitor (alpha1-PI) levels in antral mucosa and peripheral blood.
Infections
Helicobacter pylori Infection, but not Low-Dose Aspirin, Results in a Local Reduction of the Secretory Leukocyte Protease Inhibitor in Gastroduodenal Mucosa.
Infections
Hemostatic protease receptors and endothelial cell function: insights from gene targeting in mice.
Infections
Heparan sulfate-independent cell binding and infection with furin-precleaved papillomavirus capsids.
Infections
Hepatitis C infection is associated with lower lipids and high-sensitivity C-reactive protein in HIV-infected men.
Infections
Hepatitis C virus and human immunodeficiency virus: clinical issues in coinfection.
Infections
Hepatitis C virus infection suppresses GLUT2 gene expression via downregulation of hepatocyte nuclear factor 1?.
Infections
Hepatitis C virus NS4B protein targets STING and abrogates RIG-I-mediated type-I interferon-dependent innate immunity.
Infections
Hepatitis C virus-host interactions: Etiopathogenesis and therapeutic strategies.
Infections
Hepatotoxicity associated with antiretroviral therapy in adults infected with human immunodeficiency virus and the role of hepatitis C or B virus infection.
Infections
Hepatotoxicity following nevirapine-containing regimens in HIV-1-infected individuals.
Infections
Herpes simplex virus downregulation of secretory leukocyte protease inhibitor enhances human papillomavirus type 16 infection.
Infections
HHV8 and Kaposi's sarcoma: should we really give up protease inhibitors in all HIV-infected patients?
Infections
High hepatitis C virus viral load in HIV/hepatitis C virus-co-infected patients: a different influence of protease inhibitor and non-protease inhibitor-based HAART?
Infections
High incidence of non-B and recombinant HIV-1 strains in newly diagnosed patients in Galicia, Spain: study of genotypic resistance.
Infections
High prevalence and incidence of HIV-1 in a counseling and testing center in the city of Itajaí, Brazil.
Infections
High protease activity of Chryseobacterium indologenes isolates associated with invasive infection.
Infections
High Risk of Infection During Triple Therapy with First-Generation Protease Inhibitors: A Nationwide Cohort Study.
Infections
High-neurovirulence GDVII virus induces apoptosis in murine astrocytes through tumor necrosis factor (TNF)-receptor and TNF-related apoptosis-inducing ligand.
Infections
High-throughput human primary cell-based airway model for evaluating influenza, coronavirus, or other respiratory viruses in vitro.
Infections
Higher rates of triple-class virological failure in perinatally HIV-infected teenagers compared with heterosexually infected young adults in Europe.
Infections
Highly efficient full-length hepatitis C virus genotype 1 (strain TN) infectious culture system.
Infections
Histopathology of experimental invasive pulmonary aspergillosis in rats: pathological comparison of pulmonary lesions induced by specific virulent factor deficient mutants.
Infections
HIV protease inhibitors activate the unfolded protein response in macrophages: implication for atherosclerosis and cardiovascular disease.
Infections
HIV type 1 infection, and not short-term HAART, induces endothelial dysfunction.
Infections
HIV-1 genetic diversity and divergence and its correlation with disease progression among antiretroviral naïve recently infected individuals.
Infections
HIV-1 protease does not play a critical role in the early stages of HIV-1 infection.
Infections
HIV-2 Infection, End-Stage Renal Disease and Protease Inhibitor Intolerance: Which Salvage Regimen?
Infections
HIV-HCV co-infection facing HCV protease inhibitor licensing: implications for clinicians.
Infections
HIV-reverse transcriptase inhibition: inclusion of ligand-induced fit by cross-docking studies.
Infections
Homologous prime-boost strategy with TgPI-1 improves the immune response and protects highly susceptible mice against chronic Toxoplasma gondii infection.
Infections
Homologs of the LapD-LapG c-di-GMP Effector System Control Biofilm Formation by Bordetella bronchiseptica.
Infections
Horizontal and vertical transmission of human immunodeficiency virus type 1 dual infections caused by viruses of subtypes B and C.
Infections
Host defense responses to infection by Mycobacterium tuberculosis. Induction of IRF-1 and a serine protease inhibitor.
Infections
Host manipulation by bacterial type III and type IV secretion system effector proteases.
Infections
HSV-1 ICP0: An E3 Ubiquitin Ligase That Counteracts Host Intrinsic and Innate Immunity.
Infections
HtrA, a Temperature- and Stationary Phase-Activated Protease Involved in Maturation of a Key Microbial Virulence Determinant, Facilitates Borrelia burgdorferi Infection in Mammalian Hosts.
Infections
Human immunodeficiency virus protease inhibitors and risk for peripheral neuropathy.
Infections
Human immunodeficiency virus type 1 neutralization measured by flow cytometric quantitation of single-round infection of primary human T cells.
Infections
Human immunodeficiency virus type 1 protease and reverse transcriptase mutation patterns among treatment-naive patients in different stages of infection in Rio de Janeiro, Brazil.
Infections
Human immunodeficiency virus type 1 protease genotype predicts immune and viral responses to combination therapy with protease inhibitors (PIs) in PI-naive patients.
Infections
Human immunodeficiency virus type 1 protease inhibitors irreversibly block infectivity of purified virions from chronically infected cells.
Infections
Human immunodeficiency virus type 1 virions composed of unprocessed Gag and Gag-Pol precursors are capable of reverse transcribing viral genomic RNA.
Infections
Human immunodeficiency virus type-1 (HIV-1) replication is unaffected by human secretory leukocyte protease inhibitor.
Infections
Human matriptase/ST 14 proteolytically cleaves H7N9 hemagglutinin and facilitates the activation of influenza A/Shanghai/2/2013 virus in cell culture.
Infections
Human mucus protease inhibitor in airway fluids is a potential defensive compound against infection with influenza A and Sendai viruses.
Infections
Hybrid optimal control for HIV multi-drug therapies: a finite set control transcription approach.
Infections
Hydrophobic proteins secreted into the apoplast may contribute to resistance against Phytophthora infestans in potato.
Infections
Hydroxytyrosol: a new class of microbicide displaying broad anti-HIV-1 activity.
Infections
Hyperlipidaemia following treatment with protease inhibitors in patients with HIV-1 infection.
Infections
Iatrogenic hypercortisolism complicating triamcinolone acetonide injections in patients with HIV on ritonavir-boosted protease inhibitors.
Infections
Identification and analysis of the tissue factor pathway inhibitor 2 of Sciaenops ocellatus.
Infections
Identification and Characterization of IgdE, a Novel IgG-degrading Protease of Streptococcus suis with Unique Specificity for Porcine IgG.
Infections
Identification and characterization of immunodominant linear epitopes on the antigenic region of a serine protease in newborn Trichinella larvae.
Infections
Identification and characterization of putative virulence genes and gene clusters in Aeromonas hydrophila PPD134/91.
Infections
Identification and characterization of taglin, a mannose 6-phosphate binding, trypsin-activated lectin from Giardia lamblia.
Infections
Identification and functional characterization of a novel antistasin/WAP-like serine protease inhibitor from the tropical sea cucumber, Stichopus monotuberculatus.
Infections
Identification and partial characterization of a serine protease inhibitor (serpin) of Eimeria tenella.
Infections
Identification and profiling of circulating metabolites of atazanavir, a HIV protease inhibitor.
Infections
Identification and validation of uterine stimulant methylergometrine as a potential inhibitor of caspase-1 activation.
Infections
Identification of a new pathogen-induced member of the subtilisin-like processing protease family from plants.
Infections
Identification of a new protein present in vesicular stomatitis virus-infected Chinese hamster ovary cells as a degradation product of viral M protein.
Infections
Identification of Cleavage Sites Proteolytically Processed by NS2B-NS3 Protease in Polyprotein of Japanese Encephalitis Virus.
Infections
Identification of N-phenyl-N'-(2,2,6,6-tetramethyl-piperidin-4-yl)-oxalamides as a new class of HIV-1 entry inhibitors that prevent gp120 binding to CD4.
Infections
Identification of New Resistance Mechanisms in Escherichia coli against Apidaecin 1b Using Quantitative Gel- and LC-MS-Based Proteomics.
Infections
Identification of protease and rpoN-associated genes of uropathogenic Proteus mirabilis by negative selection in a mouse model of ascending urinary tract infection.
Infections
Identification of Ramie Genes in Response to Pratylenchus coffeae Infection Challenge by Digital Gene Expression Analysis.
Infections
Identification of surface proteins of Trichinella spiralis muscle larvae using immunoproteomics.
Infections
Imaging of Mycobacterium avium-intracellulare infection in AIDS patients on highly active antiretroviral therapy: reversal syndrome.
Infections
Immune complexes containing human immunodeficiency virus type 1 primary isolates bind to lymphoid tissue B lymphocytes and are infectious for T lymphocytes.
Infections
Immunisation against a serine protease inhibitor reduces intensity of Plasmodium berghei infection in mosquitoes.
Infections
Immunity-mediated regulation of fecundity in the nematode Heligmosomoides polygyrus--the potential role of mast cells.
Infections
Immunization of hamsters against Clostridium difficile infection using the Cwp84 protease as an antigen.
Infections
Immunochemical characterization and purification of Sm-97, a Schistosoma mansoni antigen monospecifically recognized by antibodies from mice protectively immunized with a nonliving vaccine.
Infections
Immunologic effects of combined protease inhibitor and reverse transcriptase inhibitor therapy in previously treated chronic HIV-1 infection.
Infections
Immunoreconstitution after ritonavir therapy in children with human immunodeficiency virus infection involves multiple lymphocyte lineages.
Infections
Impact of chicken-origin cells on adaptation of a low pathogenic influenza virus.
Infections
Impact of Clinical Parameters in the Intrahost Evolution of HIV-1 Subtype B in Pediatric Patients: A Machine Learning Approach.
Infections
Impact of etravirine use on hospitalization rates among highly pre-treated failing HIV-1 infected individuals between 2005 and 2011.
Infections
Impact of HAART exposure and associated lipodystrophy on advanced liver fibrosis in HIV/HCV-coinfected patients.
Infections
Impact of HCV protease-inhibitor-based triple therapy for chronic HCV genotype 1 infection.
Infections
Impact of PI and NNRTI HAART-based therapy on oral lesions of Brazilian HIV-infected patients.
Infections
Impact of protease inhibitor-containing combination antiretroviral therapies on height and weight growth in HIV-infected children.
Infections
Impact of protease polymorphisms and viral fitness on human immunodeficiency virus (HIV) type 1 viremia in untreated HIV-1 infection.
Infections
Impact of Staphylococcus aureus regulatory mutations that modulate biofilm formation in the USA300 strain LAC on virulence in a murine bacteremia model.
Infections
Impact of the complement lectin pathway on cytomegalovirus disease early after kidney transplantation.
Infections
Impact of the functional status of saeRS on in vivo phenotypes of Staphylococcus aureus?sarA mutants.
Infections
Impact of the SpeB protease on binding of the complement regulatory proteins factor H and factor H-like protein 1 by Streptococcus pyogenes.
Infections
Impaired fibrinolysis and increased protease levels in gastric and duodenal mucosa of patients with active duodenal ulcer.
Infections
Importance of arginine 20 of the swine vesicular disease virus 2A protease for activity and virulence.
Infections
Improved survival in mice with diet-induced pancreatitis treated with new potent protease inhibitor, E-3123 and a broad spectrum antibiotic, cefmetazole.
Infections
Improvement in neutrophil and monocyte function during highly active antiretroviral treatment of HIV-1-infected patients.
Infections
In contrast to Chlamydia trachomatis, Waddlia chondrophila grows in human cells without inhibiting apoptosis, fragmenting the Golgi apparatus, or diverting post-Golgi sphingomyelin transport.
Infections
In Silico Identification of a Potent Arsenic Based Approved Drug Darinaparsin against SARS-CoV-2: Inhibitor of RNA Dependent RNA polymerase (RdRp) and Essential Proteases.
Infections
In situ immunolocalization and stage-dependent expression of a secretory serine protease in Leishmania donovani and its role as a vaccine candidate.
Infections
In Vitro Activities against Cystic Fibrosis Pathogens of Synthetic Host Defence Propeptides Processed by Neutrophil Elastase.
Infections
In vitro activity and resistance profile of dasabuvir, a nonnucleoside hepatitis C virus polymerase inhibitor.
Infections
In vitro selection and characterization of hepatitis C virus serine protease variants resistant to an active-site peptide inhibitor.
Infections
In vitro silencing of a serine protease inhibitor suppresses Trichinella spiralis invasion, development, and fecundity.
Infections
In vivo administration of ritonavir worsens intestinal damage caused by cyclooxygease inhibitors.
Infections
In vivo bacterial protease production during Pseudomonas aeruginosa corneal infection.
Infections
In vivo characterization of host and bacterial protease expression during Pseudomonas aeruginosa corneal infections in naive and immunized mice.
Infections
In vivo-activated mononuclear phagocytes and protective immunity to chlamydiae in mice.
Infections
Incidence of virological failure and major regimen change of initial combination antiretroviral therapy in the Latin America and the Caribbean: an observational cohort study.
Infections
Incompetence of Neutrophils to Invasive Group A streptococcus Is Attributed to Induction of Plural Virulence Factors by Dysfunction of a Regulator.
Infections
Increased expression of MDR1 mRNAs and P-glycoprotein in placentas from HIV-1 infected women.
Infections
Increased risk of lipodystrophy when nucleoside analogue reverse transcriptase inhibitors are included with protease inhibitors in the treatment of HIV-1 infection.
Infections
Indinavir-Loaded Nanostructured Lipid Carriers to Brain Drug Delivery: Optimization, Characterization and Neuropharmacokinetic Evaluation.
Infections
Induction of cell-mediated immune responses in mice by DNA vaccines that express hepatitis C virus NS3 mutants lacking serine protease and NTPase/RNA helicase activities.
Infections
Infection with Langat Flavivirus or expression of the envelope protein induces apoptotic cell death.
Infections
Infection-related activation of the cg12 promoter is conserved between actinorhizal and legume-rhizobia root nodule symbiosis.
Infections
Infection-related surface proteins on conidia of the nematophagous fungus Drechmeria coniospora.
Infections
Inflammatory responses in the intestine during tapeworm infections. Mucosal mast cells and mucosal mast cell proteases in Sprague-Dawley rats infected with Hymenolepis diminuta.
Infections
Influence of jasmonic acid as potential activator of induced resistance against Karnal bunt in developing spikes of wheat.
Infections
Influenza A virus-induced autophagy contributes to enhancement of virus infectivity by SOD1 downregulation in alveolar epithelial cells.
Infections
Influenza virus-cytokine-protease cycle in the pathogenesis of vascular hyperpermeability in severe influenza.
Infections
Inhaled Fluticasone Causes Iatrogenic Cushing's Syndrome in Patients Treated with Ritonavir.
Infections
Inhibition of atazanavir oral absorption by lansoprazole gastric Acid suppression in healthy volunteers.
Infections
Inhibition of endosome-lysosome system acidification enhances porcine circovirus 2 infection of porcine epithelial cells.
Infections
Inhibition of HIV by an anti-HIV protease synthetic peptide blocks an early step of viral replication.
Infections
Inhibition of human immunodeficiency virus type 1 infectivity by secretory leukocyte protease inhibitor occurs prior to viral reverse transcription.
Infections
Inhibition of Neutrophil Migration by Hemopexin Leads to Increased Mortality Due to Sepsis in Mice.
Infections
Inhibitors of cathepsin L prevent severe acute respiratory syndrome coronavirus entry.
Infections
Inhibitory effect of pulmonary surfactant on Sendai virus infection in rat lungs.
Infections
Initiation of HAART during acute simian immunodeficiency virus infection rapidly controls virus replication in the CNS by enhancing immune activity and preserving protective immune responses.
Infections
Insight into the intermolecular recognition mechanism involved in complement component 4 activation through serine protease-trypsin.
Infections
Insights into the Autoproteolytic Processing and Catalytic Mechanism of the Chlamydia trachomatis Virulence-Associated Protease CPAF.
Infections
Interaction Between the Neglected Tropical Disease Human Schistosomiasis and HCV Infection in Egypt: a Puzzling Relationship.
Infections
Interaction of dipeptide prodrugs of saquinavir with multidrug resistance protein-2 (MRP-2): Evasion of MRP-2 mediated efflux.
Infections
Interferon-based combination treatment for chronic hepatitis C in the era of direct acting antivirals.
Infections
Interleukin-1 beta converting enzyme-like protease involvement in Fas-induced and activation-induced peripheral blood T cell apoptosis in HIV infection. TNF-related apoptosis-inducing ligand can mediate activation-induced T cell death in HIV infection.
Infections
Interrelationships between digestive proteolytic activities and production and quantitation of toxins in pseudomembranous colitis induced by Clostridium difficile in gnotobiotic mice.
Infections
Intracellular Leishmania amazonensis amastigotes internalize and degrade MHC class II molecules of their host cells.
Infections
Intracellular/surface moonlighting proteins that aid in the attachment of gut microbiota to the host.
Infections
Introduction and Utilization of High Priced HCV Medicines across Europe; Implications for the Future.
Infections
Investigation of the significance of Oil Red O-positive macrophage excess in bronchoalveolar lavage fluid during HIV infection.
Infections
IrSPI, a tick serine protease inhibitor involved in tick feeding and Bartonella henselae infection.
Infections
Is the atherosclerotic process accentuated under conditions of HIV infection, antiretroviral therapy, and protease inhibitor exposure? Meta-analysis of the markers of arterial structure and function.
Infections
iTRAQ-based proteomic study of the effects of Spiroplasma eriocheiris on Chinese mitten crab Eriocheir sinensis hemocytes.
Infections
iTRAQ-based quantitative proteomics analysis of molecular mechanisms associated with Bombyx mori (Lepidoptera) larval midgut response to BmNPV in susceptible and near-isogenic strains.
Infections
Kallikrein 13 serves as a priming protease during infection by the human coronavirus HKU1.
Infections
Kallikrein-8 Proteolytically Processes Human Papillomaviruses in the Extracellular Space To Facilitate Entry into Host Cells.
Infections
L'entrée du virus Ébola et Marburg : interaction entre la glycoprotéine virale et les facteurs cellulaires.
Infections
Lack of Association Between Genetic Variants at ACE2 and TMPRSS2 Genes Involved in SARS-CoV-2 Infection and Human Quantitative Phenotypes.
Infections
Lectin activation in Giardia lamblia by host protease: a novel host-parasite interaction.
Infections
Legionella pneumophila major acid phosphatase and its role in intracellular infection.
Infections
Legionella pneumophila Type II Secretion Dampens the Cytokine Response of Infected Macrophages and Epithelia.
Infections
Leishmania donovani secretory serine protease alters macrophage inflammatory response via COX-2 mediated PGE-2 production.
Infections
Levels of vaginal secretory leukocyte protease inhibitor are decreased in women with lower reproductive tract infections.
Infections
Life-threatening interactions between HIV-1 protease inhibitors and the illicit drugs MDMA and gamma-hydroxybutyrate.
Infections
Limited proteolysis induces woodchuck hepatitis virus infectivity for human HepG2 cells.
Infections
Lipodystrophy in patients with HIV-1 infection: effect of stopping protease inhibitors on TNF-alpha and TNF-receptor levels, and on metabolic parameters.
Infections
Listeriolysin O-dependent bacterial entry into the cytoplasm is required for calpain activation and interleukin-1 alpha secretion in macrophages infected with Listeria monocytogenes.
Infections
Liver transcriptomic changes associated with ritonavir-induced hyperlipidemia in sensitive and resistant strains of rats.
Infections
Local and systemic humoral immune response in farmed Atlantic salmon (Salmo salar L.) under a natural amoebic gill disease outbreak.
Infections
Lon protease activity causes down-regulation of Salmonella pathogenicity island 1 invasion gene expression after infection of epithelial cells.
Infections
Lon, a stress-induced ATP-dependent protease, is critically important for systemic Salmonella enterica serovar typhimurium infection of mice.
Infections
Long-term (120-Week) antiviral efficacy and tolerability of fosamprenavir/ritonavir once daily in therapy-naive patients with HIV-1 infection: an uncontrolled, open-label, single-arm follow-on study.
Infections
Long-term affected flat oyster (Ostrea edulis) haemocytes show differential gene expression profiles from naïve oysters in response to Bonamia ostreae.
Infections
Long-Term Efficacy, Tolerability, and Renal Safety of Atazanavir/Ritonavir-based Antiretroviral Therapy in a Cohort of Treatment-Naïve Patients with HIV-1 Infection: the REMAIN Study.
Infections
LPS AND TNF-? INHIBIT INTERFERON-SIGNALING IN HEPATOCYTES BY INCREASING USP18 EXPRESSION.
Infections
Management of infection among Medicare beneficiaries with HIV/AIDS: risk of diabetes with protease inhibitors and associated racial disparities using big data approach.
Infections
Management of post liver transplantation recurrent hepatitis C infection with directly acting antiviral drugs: a review.
Infections
Manduca sexta serpin-4 and serpin-5 inhibit the prophenol oxidase activation pathway: cDNA cloning, protein expression, and characterization.
Infections
Mannose-binding lectin and mannose-binding protein-associated serine protease 2 levels and infection in very-low-birth-weight infants.
Infections
Mast cells that reside at different locations in the jejunum of mice infected with Trichinella spiralis exhibit sequential changes in their granule ultrastructure and chymase phenotype.
Infections
Master Sculptor at Work: Enteropathogenic Escherichia coli Infection Uniquely Modifies Mitochondrial Proteolysis during Its Control of Human Cell Death.
Infections
May viral (antigen) load be the real crucial tool leading to anergy in a "micro-evolutionary" model of host/virus interaction?
Infections
Mechanism of inhibition of the human immunodeficiency virus type 1 by the oxygen radical generating agent bleomycin.
Infections
Membrane fusion and cell entry of XMRV are pH-independent and modulated by the envelope glycoprotein's cytoplasmic tail.
Infections
Mericitabine and Either Boceprevir or Telaprevir in Combination with Peginterferon Alfa-2a plus Ribavirin for Patients with Chronic Hepatitis C Genotype 1 Infection and Prior Null Response: The Randomized DYNAMO 1 and DYNAMO 2 Studies.
Infections
Metabolic effects of protease inhibitor-sparing antiretroviral regimens given as initial treatment of HIV-1 Infection (AIDS Clinical Trials Group Study A5095).
Infections
Metabolic response to a C-glucose load in human immunodeficiency virus patients before and after antiprotease therapy.
Infections
Metal-mediated modulation of streptococcal cysteine protease activity and its biological implications.
Infections
Methicillin resistance alters the biofilm phenotype and attenuates virulence in Staphylococcus aureus device-associated infections.
Infections
Microenvironment of Gyrodactylus derjavini on rainbow trout Oncorhynchus mykiss: association between mucous cell density in skin and site selection.
Infections
Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Infection Mediated by the Transmembrane Serine Protease TMPRSS2.
Infections
Mj-DWD, a double WAP domain-containing protein with antiviral relevance in Marsupenaeus japonicus.
Infections
MK-5172 : a second-generation protease inhibitor for the treatment of hepatitis C virus infection.
Infections
Model for simulation of HIV/AIDS and cost-effectiveness of preventing non-tuberculous mycobacterial (MAC)-disease.
Infections
Modeling changes in CD4-positive T-lymphocyte counts after the start of highly active antiretroviral therapy and the relation with risk of opportunistic infections: the Aquitaine Cohort, 1996-1997.
Infections
Modulation of lysosomal protease-esterase and lysozyme in Kupffer cells and peritoneal macrophages infected with Nocardia asteroides.
Infections
Modulation of the biologic activities of IgE-binding factor. V. The role of glycosylation-enhancing factor and glycosylation-inhibiting factor in determining the nature of IgE-binding factors.
Infections
Molecular characterization and expression of complement factor I in Pelteobagrus vachellii during Aeromonas hydrophila infection.
Infections
Molecular characterization of hepatitis C virus for determination of subtypes and detection of resistance mutations to protease inhibitors in a group of intravenous drug users co-infected with HIV.
Infections
Molecular characterization of protease activity in Serratia sp. strain SCBI and its importance in cytotoxicity and virulence.
Infections
Molecular characterization, expression and antimicrobial activity of complement factor D in Megalobrama amblycephala.
Infections
Molecular Cloning and Characterization of a Subtilisin-Like Serine Protease Gene (Pr1) from the Medicinal Chinese Caterpillar Mushroom, Ophiocordyceps sinensis (Ascomycetes).
Infections
Molecular Determinants of Epistasis in HIV-1 Protease: Elucidating the Interdependence of L89V and L90M Mutations in Resistance.
Infections
Molecular mechanism of complex infection by bacteria and virus analyzed by a model using serratial protease and influenza virus in mice.
Infections
Multicenter Experience with Boceprevir or Telaprevir to Treat Hepatitis C Recurrence after Liver Transplantation: When Present Becomes Past, What Lessons for Future?
Infections
Multidrug-resistant tuberculosis (MDR-TB) and multidrug-resistant HIV (MDR-HIV) syndemic: challenges in resource limited setting.
Infections
Multiple classes of immune-related proteases associated with the cell death response in pepper plants.
Infections
Multiple virulence factors regulated by quorum sensing may help in establishment and colonisation of urinary tract by Pseudomonas aeruginosa during experimental urinary tract infection.
Infections
Mutations in the IGF-II pathway that confer resistance to lytic reovirus infection.
Infections
Mycobacterial excretory secretory-31 protein with serine protease and lipase activities: An immunogen and drug target against tuberculosis infection.
Infections
Mycobacterium avium complex causing endobronchial disease in AIDS patients after partial immune restoration.
Infections
Mycobacterium tuberculosis MycP1 protease plays a dual role in regulation of ESX-1 secretion and virulence.
Infections
Myxoma viral serpin, Serp-1, inhibits human monocyte adhesion through regulation of actin-binding protein filamin B.
Infections
N-Naphthoyl-substituted indole thio-barbituric acid analogs inhibit the helicase activity of the hepatitis C virus NS3.
Infections
Nafamostat mesylate inhibits chlamydial intracellular growth in cell culture and reduces chlamydial infection in the mouse genital tract.
Infections
Naive T cells sense the cysteine protease allergen papain through protease-activated receptor 2 and propel TH2 immunity.
Infections
Nationwide experience of treatment with protease inhibitors in chronic hepatitis C patients in denmark: identification of viral resistance mutations.
Infections
Nature of equilibria and effects of drug treatments in some simple viral population dynamical models.
Infections
NDR1 interaction with RIN4 mediates the differential activation of multiple disease resistance pathways in Arabidopsis.
Infections
Neurovirulent Murine Coronavirus JHM.SD Uses Cellular Zinc Metalloproteases for Virus Entry and Cell-Cell Fusion.
Infections
Neutrophil elastase and secretory leukocyte protease inhibitor in prelabor rupture of membranes, parturition and intra-amniotic infection.
Infections
Neutrophil elastase, an acid-independent serine protease, facilitates reovirus uncoating and infection in U937 promonocyte cells.
Infections
Neutrophils Select Hypervirulent CovRS Mutants of M1T1 Group A Streptococcus during Subcutaneous Infection of Mice.
Infections
Nevirapine plus efavirenz plus didanosine: a simple, safe, and effective once-daily regimen for patients with HIV infection.
Infections
Nevirapine-containing antiretroviral therapy in HIV-1 infected patients results in an anti-atherogenic lipid profile.
Infections
New aspects of integrin-mediated leukocyte adhesion in inflammation: regulation by haemostatic factors and bacterial products.
Infections
New perspectives in understanding and management of the respiratory disease in cystic fibrosis.
Infections
New resistance-associated substitutions and failure of dual oral therapy with daclatasvir and asunaprevir.
Infections
NLRP3/ASC/Caspase-1 axis and serine protease activity are involved in neutrophil IL-1? processing during Streptococcus pneumoniae infection.
Infections
No Clinically Relevant Drug-Drug Interactions between Methadone or Buprenorphine-Naloxone and Antiviral Combination Glecaprevir and Pibrentasvir.
Infections
No increase in protease resistance and a decrease in reverse transcriptase resistance mutations in primary HIV-1 infection: 1992-2001.
Infections
Non-nucleoside HIV-1 reverse transcriptase (RT) inhibitors: past, present, and future perspectives.
Infections
Non-nucleoside reverse transcriptase inhibitors: perspectives on novel therapeutic compounds and strategies for the treatment of HIV infection.
Infections
Noncanonical Wnt signaling promotes osteoclast differentiation and is facilitated by the human immunodeficiency virus protease inhibitor ritonavir.
Infections
Not so sweet: autoimmune diabetes mellitus on triple therapy for chronic hepatitis C infection.
Infections
Novel Analogues of the Chikungunya Virus Protease Inhibitor: Molecular Design, Synthesis, and Biological Evaluation.
Infections
Novel apoptosis suppressor Apsup from the baculovirus Lymantria dispar multiple nucleopolyhedrovirus precludes apoptosis by preventing proteolytic processing of initiator caspase Dronc.
Infections
Nucleoside analogs plus ritonavir in stable antiretroviral therapy-experienced HIV-infected children: a randomized controlled trial. Pediatric AIDS Clinical Trials Group 338 Study Team.
Infections
Nucleotide and amino acid polymorphisms at drug resistance sites in non-B-subtype variants of human immunodeficiency virus type 1.
Infections
Null Mutations of Group A Streptococcus Orphan Kinase RocA: Selection in Mouse Infection and Comparison with CovS Mutations in Alteration of In Vitro and In Vivo Protease SpeB Expression and Virulence.
Infections
Ombitasvir, paritaprevir, and ritonavir plus ribavirin in adults with hepatitis C virus genotype 4 infection and cirrhosis (AGATE-I): a multicentre, phase 3, randomised open-label trial.
Infections
Ontogeny constrains systemic protease inhibitor response in Nicotiana attenuata.
Infections
Oral immunization with ATP-dependent protease-deficient mutants protects mice against subsequent oral challenge with virulent Salmonella enterica serovar typhimurium.
Infections
Otitis media in children with vertically-acquired HIV infection: the Great Ormond Street Hospital experience.
Infections
Out-Smarting the Host: Bacteria Maneuvering the Immune Response to Favor Their Survival.
Infections
Overexpression of Gloverin2 in the Bombyx mori silk gland enhances cocoon/silk antimicrobial activity.
Infections
Overexpression of the HIV-1 gag-pol polyprotein results in intracellular activation of HIV-1 protease and inhibition of assembly and budding of virus-like particles.
Infections
Overview of the PROVE studies evaluating the use of telaprevir in chronic hepatitis C genotype 1 patients.
Infections
P-glycoprotein mediates efflux transport of darunavir in human intestinal Caco-2 and ABCB1 gene-transfected renal LLC-PK1 cell lines.
Infections
Pan?cancer analysis of transmembrane protease serine 2 and cathepsin L that mediate cellular SARS?CoV?2 infection leading to COVID-19.
Infections
Parasite killing in Plasmodium vivax malaria by nitric oxide: implication of aspartic protease inhibition.
Infections
Parvovirus Capsid Structures Required for Infection: Mutations Controlling Receptor Recognition and Protease Cleavages.
Infections
Pathogenesis of serratial infection: activation of the Hageman factor-prekallikrein cascade by serratial protease.
Infections
Pathogenicity patterns of mucormycosis: epidemiology, interaction with immune cells and virulence factors.
Infections
Peptide inhibitors of HIV-1 protease and viral infection of peripheral blood lymphocytes based on HIV-1 Vif.
Infections
Peptidomimetic furin inhibitor MI-701 in combination with oseltamivir and ribavirin efficiently blocks propagation of highly pathogenic avian influenza viruses and delays high level oseltamivir resistance in MDCK cells.
Infections
Periodontal pathogens affect the level of protease inhibitors in gingival crevicular fluid.
Infections
Persistence of bovine viral diarrhea virus is determined by a cellular cofactor of a viral autoprotease.
Infections
Persistent hepatitis C virus infections and hepatopathological manifestations in immune-competent humanized mice.
Infections
Persistent Salmonella enterica Serovar Typhimurium Infection Induces Protease Expression During Intestinal Fibrosis.
Infections
Perspectives of non-nucleoside reverse transcriptase inhibitors (NNRTIs) in the therapy of HIV-1 infection.
Infections
Phage-protease-peptide: a novel trifecta enabling multiplex detection of viable bacterial pathogens.
Infections
Pharmacokinetics and pharmacodynamics of sildenafil in a patient treated with human immunodeficiency virus protease inhibitors.
Infections
Pharmacological Modulators of Autophagy as a Potential Strategy for the Treatment of COVID-19.
Infections
Pharmacological Therapeutics Targeting RNA-Dependent RNA Polymerase, Proteinase and Spike Protein: From Mechanistic Studies to Clinical Trials for COVID-19.
Infections
Phenotypic analysis of the sensitivity of HIV-1 to inhibitors of the reverse transcriptase, protease, and integrase using a self-inactivating virus vector system.
Infections
Phenotypic hypersusceptibility to multiple protease inhibitors and low replicative capacity in patients who are chronically infected with human immunodeficiency virus type 1.
Infections
Phosphothreonine Lyase Promotes p65 Degradation in a Mitogen-Activated Protein Kinase/Mitogen- and Stress-Activated Protein Kinase 1-Dependent Manner.
Infections
Phylogenetic analysis of protease and transmembrane region of HIV type 1 group O.
Infections
Physicochemical characterisation, immunogenicity and protective efficacy of a lead streptococcal vaccine: progress towards Phase I trial.
Infections
Picornavirus receptor down-regulation by plasminogen activator inhibitor type 2.
Infections
Plasma bile acid concentrations in patients with human immunodeficiency virus infection receiving protease inhibitor therapy: possible implications for hepatotoxicity.
Infections
Plasma citrulline is a biomarker of enterocyte mass and an indicator of parenteral nutrition in HIV-infected patients.
Infections
Plasma levels of the von Willebrand factor-cleaving protease in physiological and pathological conditions in children.
Infections
Plasminogen promotes influenza A virus replication through an annexin 2-dependent pathway in the absence of neuraminidase.
Infections
Polymorphic exocellular protease expression in clinical isolates of Trichophyton tonsurans.
Infections
Polyprotein processing and intermolecular interactions within the viral replication complex spatially and temporally control norovirus protease activity.
Infections
Population pharmacokinetics and dosing regimen optimisation of lopinavir in Chinese adults infected with HIV.
Infections
Porcine aminopeptidase N is not a cellular receptor of porcine epidemic diarrhoea virus, but promotes its infectivity via aminopeptidase activity.
Infections
Porcine deltacoronavirus enters cells via two pathways: A protease-mediated one at the cell surface and another facilitated by cathepsins in the endosome.
Infections
Porphyromonas gingivalis and its lipopolysaccharide differentially regulate the expression of cathepsin B in endothelial cells.
Infections
Potent inhibition of HIV type 1 infection of mononuclear phagocytes by synthetic peptide analogs of HIV type 1 protease substrates.
Infections
Potentiation of infectivity and pathogenesis of influenza A virus by a house dust mite protease.
Infections
Prediction of minimal residual viremia in HCV type 1 infected patients receiving interferon-based therapy.
Infections
Predictors of early treatment discontinuation and severe anemia in a Brazilian cohort of hepatitis C patients treated with first-generation protease inhibitors.
Infections
Presence of an inducible HIV-1 latent reservoir during highly active antiretroviral therapy.
Infections
Prevalence and Risk Factors for Significant Liver Fibrosis in Patients with HIV Infection.
Infections
Prevalence of comedications and effect of potential drug-drug interactions in the Swiss HIV Cohort Study.
Infections
Prevalence of genes encoding extracellular proteases in Staphylococcus aureus - important targets triggering immune response in vivo.
Infections
Prevalence of protease and elastase production by clinical isolates of Pseudomonas aeruginosa in relation to aeruginocine typing patterns.
Infections
Prevalence of transmitted nucleoside analogue-resistant HIV-1 strains and pre-existing mutations in pol reverse transcriptase and protease region: outcome after treatment in recently infected individuals.
Infections
Preventing Cushing: Iatrogenic Cushing Syndrome due to Ritonavir-Fluticasone Interaction.
Infections
Primary HIV-1 drug resistance in Spain before and after the introduction of protease inhibitors.
Infections
Primary HIV-1 infection: a review of clinical manifestations, immunologic and virologic changes.
Infections
Production of a biopesticide on host and Non-Host serine protease inhibitors for red palm weevil in palm trees.
Infections
Profile of CGP 61755: a novel and potent HIV-1 protease inhibitor that shows enhanced anti-HIV activity when combined with other antiretroviral agents in vitro.
Infections
Prolyl endopeptidase activity in bronchoalveolar lavage fluid: a novel diagnostic biomarker in a guinea pig model of invasive pulmonary aspergillosis.
Infections
Promiscuous, Multi-Target Lupane-Type Triterpenoids Inhibits Wild Type and Drug Resistant HIV-1 Replication Through the Interference With Several Targets.
Infections
Pronounced anti-HIV-1 activity of foscarnet in patients without cytomegalovirus infection.
Infections
Protease activity and phytocystatin expression in Arabidopsis thaliana upon Heterodera schachtii infection.
Infections
Protease activity in the plasma of American oysters, Crassostrea virginica, experimentally infected with the protozoan parasite Perkinsus marinus.
Infections
Protease activity sensors noninvasively classify bacterial infections and antibiotic responses.
Infections
Protease and virulence of the extracellular products produced by Vibrio carchariae after growth on various media.
Infections
Protease inhibitor combination therapy, severity of illness, and quality of life among children with perinatally acquired HIV-1 infection.
Infections
Protease inhibitor monotherapy was non-inferior and cost-effective as maintenance therapy compared to triple therapy in viral load suppressed patients with HIV-1 infection.
Infections
Protease inhibitor treatment effect on aortic stiffness in normotensive patients with human immunodeficiency virus infection.
Infections
Protease inhibitor-based direct-acting antivirals are associated with increased risk of aminotransferase elevations but not hepatic dysfunction or decompensation.
Infections
Protease inhibitors and haemagglutinins associated with resistance to the protozoan parasite, Perkinsus marinus, in the Pacific oyster, Crassostrea gigas.
Infections
Protease inhibitors as potential antiviral agents for the treatment of picornaviral infections.
Infections
Protease inhibitors elicit anti-inflammatory effects in CF mice with Pseudomonas aeruginosa acute lung infection.
Infections
Protease inhibitors for the treatment of chronic hepatitis C genotype-1 infection: the new standard of care.
Infections
Protease inhibitors in Bombyx mori silk might participate in protecting the pupating larva from microbial infection.
Infections
Protease inhibitors in bronchoalveolar lavage fluid from neonates with special reference to secretory leukocyte protease inhibitor.
Infections
Protease inhibitors-based therapy induces acquired spherocytic-like anaemia and ineffective erythropoiesis in chronic hepatitis C virus patients.
Infections
Protease pretreatment increases the efficacy of adenovirus-mediated gene therapy for the treatment of an experimental glioblastoma model.
Infections
Protease production by microorganisms associated with reproductive tract infection.
Infections
Protease resistance of infectious prions is suppressed by removal of a single atom in the cellular prion protein.
Infections
Protease sequences from HIV-1 group M subtypes A-H reveal distinct amino acid mutation patterns associated with protease resistance in protease inhibitor-naive individuals worldwide. HIV Variant Working Group.
Infections
Protease-mediated enhancement of severe acute respiratory syndrome coronavirus infection.
Infections
Protease-stable polycationic photosensitizer conjugates between polyethyleneimine and chlorin(e6) for broad-spectrum antimicrobial photoinactivation.
Infections
Proteases and Their Involvement in the Infection and Immobilization of Nematodes by the Nematophagous Fungus Arthrobotrys oligospora.
Infections
Proteases essential for human influenza virus entry into cells and their inhibitors as potential therapeutic agents.
Infections
Protection of mice from wild-type Sendai virus infection by a trypsin-resistant mutant, TR-2.
Infections
Protective effect of a cephalosporin, Shiomarin, plus a new potent protease inhibitor, E3123, on rat taurocholate-induced pancreatitis.
Infections
Protective immune responses against protease-like antigens of the murine malaria parasite Plasmodium vinckei.
Infections
Protective immunity against Trichinella spiralis in mice elicited by oral vaccination with attenuated Salmonella-delivered TsSP1.2 DNA.
Infections
Proteinase pattern of honeybee prepupae from healthy and American Foulbrood infected bees investigated by zymography.
Infections
Proteolytic activation of the porcine epidemic diarrhea coronavirus spike fusion protein by trypsin in cell culture.
Infections
Proteolytic cleavage of the E2 glycoprotein of murine coronavirus: host-dependent differences in proteolytic cleavage and cell fusion.
Infections
Proteolytic cleavage of VP1-2 is required for release of herpes simplex virus 1 DNA into the nucleus.
Infections
Proteome profiling reveals tissue-specific protein expression in male and female accessory glands of the silkworm, Bombyx mori.
Infections
Proteomic Analysis of Trichinella spiralis Adult Worm Excretory-Secretory Proteins Recognized by Sera of Patients with Early Trichinellosis.
Infections
Proteomics approaches for the identification of protease substrates during virus infection.
Infections
Proteotoxic stress induced by Autographa californica nucleopolyhedrovirus infection of Spodoptera frugiperda Sf9 cells.
Infections
Provisional Guidance on the Use of Hepatitis C Virus Protease Inhibitors for Treatment of Hepatitis C in HIV-Infected Persons.
Infections
Pseudomonas aeruginosa elastase disrupts the cortisol-binding activity of corticosteroid-binding globulin.
Infections
Pseudomonas aeruginosa Keratitis: Protease IV and PASP as Corneal Virulence Mediators.
Infections
Pseudomonas aeruginosa RhlR is required to neutralize the cellular immune response in a Drosophila melanogaster oral infection model.
Infections
Pseudomonas deficient in protease IV has significantly reduced corneal virulence.
Infections
Pseudomonas protease. Purification, partial characterization, and its effect on collagen, proteoglycan, and rabbit corneas.
Infections
Purification and characterization of a 31 kDa mycobacterial excretory-secretory antigenic protein with a diagnostic potential in pulmonary tuberculosis.
Infections
Purification and characterization of alpha2-macroglobulin from grass carp Ctenopharyngodon idellus: cloning a segment of the corresponding gene.
Infections
Purification and characterization of an extracellular serine protease from the nematode-trapping fungus Dactylella shizishanna.
Infections
Purification and cloning of a novel serine protease from the nematode-trapping fungus Dactylellina varietas and its potential roles in infection against nematodes.
Infections
Quantitative analysis of differentially expressed saliva proteins in human immunodeficiency virus type 1 (HIV-1) infected individuals.
Infections
Quantitative collection and proteolytic activity of preacetabular gland enzyme (s) of cercariae of schistosoma mansoni.
Infections
Quantitative label-free proteomic analysis reveals differentially expressed proteins in the digestive juice of resistant versus susceptible silkworm strains and their predicted impacts on BmNPV infection.
Infections
Quantum Mechanics/Molecular Mechanics (QM/MM) Calculations Support a Concerted Reaction Mechanism for the Zika Virus NS2B/NS3 Serine Protease with Its Substrate.
Infections
Quercetin a major biomarker of Psidium guajava L. inhibits SepA protease activity of Shigella flexneri in treatment of infectious diarrhoea.
Infections
Randomized trial of time-limited interruptions of protease inhibitor-based antiretroviral therapy (ART) vs. continuous therapy for HIV-1 infection.
Infections
Rapid reversion of a deletion mutation in Moloney murine leukemia virus by recombination with a closely related endogenous provirus.
Infections
Rapidly evolving hepatitis C virus-related cirrhosis in a human immunodeficiency virus-infected patient receiving triple antiretroviral therapy.
Infections
RD19, an Arabidopsis Cysteine Protease Required for RRS1-R-Mediated Resistance, Is Relocalized to the Nucleus by the Ralstonia solanacearum PopP2 Effector.
Infections
Reaching the melting point: Degradative enzymes and protease inhibitors involved in baculovirus infection and dissemination.
Infections
Real-time molecular epidemiologic analysis of an outbreak of Streptococcus pyogenes invasive disease in US Air Force trainees.
Infections
Reassessing the role of the secreted protease CPAF in Chlamydia trachomatis infection through genetic approaches.
Infections
Recent Advances in the Discovery of Potent Proteases Inhibitors Targeting the SARS Coronaviruses.
Infections
Recent Advances in the Study of the Inclusion Complex Darunavir-?-Cyclodextrin by LC-MS.
Infections
Recent patents relating to HCV molecules like putative targets for therapeutic intervention.
Infections
Recombinant feline herpesviruses expressing feline leukemia virus envelope and gag proteins.
Infections
Recommendations for the use of hepatitis C virus protease inhibitors for the treatment of chronic hepatitis C in HIV-infected persons. A position paper of the Italian Association for the Study of Infectious and Tropical Disease.
Infections
Reduction in cell entry of Eimeria tenella (Coccidia) sporozoites by protease inhibitors, and partial characterization of proteolytic activity associated with intact sporozoites and merozoites.
Infections
Regression of liver stiffness after sustained hepatitis C virus (HCV) virological responses among HIV/HCV-coinfected patients.
Infections
Regulation of Semliki Forest virus RNA replication: a model for the control of alphavirus pathogenesis in invertebrate hosts.
Infections
Regulation of tumor necrosis factor alpha and its specific receptors during Toxoplasma gondii infection in human monocytic cells.
Infections
Regulatory and Metabolic Networks for the Adaptation of Pseudomonas aeruginosa Biofilms to Urinary Tract-Like Conditions.
Infections
Related Endogenous Retrovirus-K Elements Harbor Distinct Protease Active Site Motifs.
Infections
Relationship between in vitro human immunodeficiency virus type 1 replication rate and virus load in plasma.
Infections
Relationships between host blood factors and proteases in Glossina morsitans subspecies infected with Trypanosoma congolense.
Infections
Relationships between protease activity, host blood and infection rates in Glossina morsitans sspp. infected with Trypanosoma congolense, T. brucei and T. simiae.
Infections
Relative efficacy and safety of simeprevir and telaprevir in treatment-naïve hepatitis C-infected patients in a Japanese population: A Bayesian network meta-analysis.
Infections
Removal of zinc is required for processing of the mature nucleocapsid protein of human immunodeficiency virus, type 1, by the viral protease.
Infections
Repurposing anti-diabetic drug "Sitagliptin" as a novel virulence attenuating agent in Serratia marcescens.
Infections
Residual human immunodeficiency virus type 1 RNA in lymphoid tissue of patients with sustained plasma RNA of <200 copies/mL.
Infections
Resistance analyses of integrase strand transfer inhibitors within phase 3 clinical trials of treatment-naive patients.
Infections
Resistance profiles to antiretroviral drugs in HIV-1 drug-naive patients in Argentina.
Infections
Resistance to protease inhibitors in a model of HIV-1 infection with impulsive drug effects.
Infections
Resistance-associated mutations to HCV protease inhibitors naturally pre-existed in HIV/HCV coinfected, treatment-naïve patients.
Infections
Respiratory failure associated with the lipodystrophy syndrome in an HIV-positive patient with compromised lung function.
Infections
Respiratory syncytial virus (RSV) entry is inhibited by serine protease inhibitor AEBSF when present during an early stage of infection.
Infections
Respiratory syncytial virus infections enhance cigarette smoke induced COPD in mice.
Infections
Restoration of immunity to chronic hepatitis B infection in HIV-infected patient on protease inhibitor.
Infections
Restricted Theiler's murine encephalomyelitis virus infection in murine macrophages induces apoptosis.
Infections
Results of interferon-based treatments in Alaska Native and American Indian population with chronic hepatitis C.
Infections
RETREG1 (FAM134B): A new player in human diseases: 15 years after the discovery in cancer.
Infections
Retrovirus-like particles produced by vaccinia viruses expressing gag-pro-pol region genes of bovine leukaemia virus.
Infections
Rhinovirus 3C Protease Facilitates Specific Nucleoporin Cleavage and Mislocalisation of Nuclear Proteins in Infected Host Cells.
Infections
Rickettsia conorii infection stimulates the expression of ISG15 and ISG15 protease UBP43 in human microvascular endothelial cells.
Infections
Risk of premature atherosclerosis and ischemic heart disease associated with HIV infection and antiretroviral therapy.
Infections
Ritonavir-boosted protease inhibitor monotherapy for the treatment of HIV-1 infection.
Infections
RNA dependent RNA polymerase of HCV: A potential target for the development of antiviral drugs.
Infections
RNA-seq reveals the critical role of Lon protease in stress response and Brucella virulence.
Infections
Role for a secreted cysteine proteinase in the establishment of host tissue tropism by group A streptococci.
Infections
Role of exotoxin A and proteases of Pseudomonas aeruginosa in respiratory tract infections.
Infections
Role of exotoxin and protease as possible virulence factors in experimental infections with Pseudomonas aeruginosa.
Infections
Role of Iron Chelation and Protease Inhibition of Natural Products on COVID-19 Infection.
Infections
Role of lymphocyte multidrug resistance protein 1 in HIV infection: expression, function, and consequences of inhibition.
Infections
Role of protease in mouse hepatitis virus-induced cell fusion. Studies with a cold-sensitive mutant isolated from a persistent infection.
Infections
Role of protease inhibitor 9 in survival and replication of Mycobacterium tuberculosis in mononuclear phagocytes from HIV-1-infected patients.
Infections
Role of proteases in the release of porcine epidemic diarrhea virus from infected cells.
Infections
Role of viral and host factors in interferon based therapy of hepatitis C virus infection.
Infections
Role of xanthine oxidase activation and reduced glutathione depletion in rhinovirus induction of inflammation in respiratory epithelial cells.
Infections
Rosellinia necatrix infection induces differential gene expression between tolerant and susceptible avocado rootstocks.
Infections
Rous sarcoma virus transforming protein lacking myristic acid phosphorylates known polypeptide substrates without inducing transformation.
Infections
Safety and antiviral activity of lopinavir/ritonavir-based therapy in human immunodeficiency virus type 1 (HIV-1) infection.
Infections
Safety and efficacy of elbasvir and grazoprevir in Japanese hemodialysis patients with genotype 1b hepatitis C virus infection.
Infections
Safety and efficacy of faldaprevir in combination with pegylated interferon ?-2b and ribavirin in Japanese patients with genotype-1 chronic hepatitis C virus infection.
Infections
Safety and efficacy of protease inhibitor based combination therapy in a single-center "real-life" cohort of 110 patients with chronic hepatitis C genotype 1 infection.
Infections
Safety and efficacy of triple therapy with peginterferon, ribavirin and boceprevir within an early access programme in Spanish patients with hepatitis C genotype 1 with severe fibrosis: SVRw12 analysis.
Infections
Safety and pharmacokinetics of brecanavir, a novel human immunodeficiency virus type 1 protease inhibitor, following repeat administration with and without ritonavir in healthy adult subjects.
Infections
Safety profile and tolerability of amprenavir in the treatment of adult and pediatric patients with HIV infection.
Infections
Salmonella enterica Serovar Typhimurium HtrA: regulation of expression and role of the chaperone and protease activities during infection.
Infections
Saquinavir enhances the mucosal toxicity of infusional cyclophosphamide, doxorubicin, and etoposide in patients with HIV-associated non-Hodgkin's lymphoma.
Infections
Saquinavir Inhibits Early Events Associated with Establishment of HIV-1 Infection: Potential Role for Protease Inhibitors in Prevention.
Infections
Schistosoma japonicum cathepsin B as potential diagnostic antigen for Asian zoonotic schistosomiasis.
Infections
Screen of Non-annotated Small Secreted Proteins of Pseudomonas syringae Reveals a Virulence Factor That Inhibits Tomato Immune Proteases.
Infections
Secretome analysis of Aspergillus fumigatus reveals Asp-hemolysin as a major secreted protein.
Infections
Secretory leukocyte protease inhibitor (SLPI): oxidation of SLPI does not explain its variable anti-HIV activity.
Infections
Secretory Leukocyte Protease Inhibitor and Elafin/Trappin-2 : Versatile Mucosal Antimicrobials and Regulators of Immunity.
Infections
Secretory leukocyte protease inhibitor binds to annexin II, a cofactor for macrophage HIV-1 infection.
Infections
Secretory leukocyte protease inhibitor expression in various types of gastritis: a specific role of Helicobacter pylori infection.
Infections
Secretory leukocyte protease inhibitor inhibits infection of monocytes and lymphocytes with human immunodeficiency virus type 1 but does not interfere with transcytosis of cell-associated virus across tight epithelial barriers.
Infections
Secretory leukocyte protease inhibitor: inhibition of human immunodeficiency virus-1 infection of monocytic THP-1 cells by a newly cloned protein.
Infections
Selection of Clinically-relevant Protease Inhibitor Resistant Viruses Using the Genotype 2a HCV Infection System.
Infections
Separation methods for nucleoside analogues used for treatment of HIV-1 infection.
Infections
Serine protease and phenoloxidase activities in hemocytes of Biomphalaria glabrata snails with varying susceptibility to infection with the parasite Schistosoma mansoni.
Infections
Serine protease autotransporters from Shigella flexneri and pathogenic Escherichia coli target a broad range of leukocyte glycoproteins.
Infections
Serine protease autotransporters of Enterobacteriaceae (SPATEs) are largely distributed among Escherichia coli isolated from the bloodstream.
Infections
Serine protease inhibitor AEBSF reduces dengue virus infection via decreased cholesterol synthesis.
Infections
Serine protease inhibitors containing a Kunitz domain: their role in modulation of host inflammatory responses and parasite survival.
Infections
Serodiagnosis of Fasciola gigantica Infection in Buffaloes with Native Cathepsin-L Proteases and Recombinant Cathepsin L1-D.
Infections
Serpin 2a is induced in activated macrophages and conjugates to a ubiquitin homolog.
Infections
SERPINA1 Gene Promoter Is Differentially Methylated in Peripheral Blood Mononuclear Cells of Pregnant Women.
Infections
Serratia marcescens serralysin induces inflammatory responses through protease-activated receptor 2.
Infections
Serum 25(OH)D3 levels affect treatment outcomes for telaprevir/peg-interferon/ribavirin combination therapy in genotype 1b chronic hepatitis C.
Infections
Serum derived protease inhibitors and leucocyte elastase in sputum and the effect of infection.
Infections
Serum IgA and IgG subclasses during treatment for acute respiratory exacerbation in cystic fibrosis: analysis of patients colonised with mucoid or non-mucoid strains of pseudomonas aeruginosa.
Infections
Severe Fever with Thrombocytopenia Virus Glycoproteins Are Targeted by Neutralizing Antibodies and Can Use DC-SIGN as a Receptor for pH-Dependent Entry into Human and Animal Cell Lines.
Infections
Shape-based Machine Learning Models for the Potential Novel COVID-19 Protease Inhibitors Assisted by Molecular Dynamics Simulation
Infections
Shigella depends on SepA to destabilize the intestinal epithelial integrity via cofilin activation.
Infections
Short and long-term effects of telaprevir on kidney function in patients with hepatitis C virus infection: a retrospective cohort study.
Infections
Short article: Faldaprevir, deleobuvir and ribavirin in IL28B non-CC patients with HCV genotype-1a infection included in the SOUND-C3 phase 2b study.
Infections
Silencing of a putative immunophilin gene in the cattle tick Rhipicephalus (Boophilus) microplus increases the infection rate of Babesia bovis in larval progeny.
Infections
Simeprevir increases rate of sustained virologic response among treatment-experienced patients with HCV genotype-1 infection: a phase IIb trial.
Infections
Simplification strategies to reduce antiretroviral drug exposure: progress and prospects.
Infections
Simultaneous dermatophytosis and keratomycosis caused by Trichophyton interdigitale infection: a case report and literature review.
Infections
Simultaneous quantification of simeprevir sodium: A hepatitis C protease inhibitor in binary and ternary mixtures with sofosbuvir and/or ledipasvir utilizing direct and H-point standard addition strategies.
Infections
Simultaneous treatment of human bronchial epithelial cells with serine and cysteine protease inhibitors prevents severe acute respiratory syndrome coronavirus entry.
Infections
Single cell resolution of SARS-CoV-2 tropism, antiviral responses, and susceptibility to therapies in primary human airway epithelium.
Infections
Single genome sequencing of HIV-1 gag and protease resistance mutations at virologic failure during the OK04 trial of simplified versus standard maintenance therapy.
Infections
Skin rash induced by ritonavir-boosted darunavir is common, but generally tolerable in an observational setting.
Infections
SLPI and AnxA2 expression in neoplasm-free palatine tonsils is associated with smoking habit of individuals.
Infections
Small molecule inhibitor E-64 exhibiting the activity against African swine fever virus pS273R.
Infections
Small-Molecule Allosteric Triggers of Clostridium difficile Toxin B Auto-proteolysis as a Therapeutic Strategy.
Infections
Small-Molecule Inhibitors of Lethal Factor Protease Activity Protect against Anthrax Infection.
Infections
Sodium alginate potentiates antioxidant defense and PR proteins against early blight disease caused by Alternaria solani in Solanum lycopersicum Linn.
Infections
Sofosbuvir in combination with peginterferon alfa-2a and ribavirin for non-cirrhotic, treatment-naive patients with genotypes 1, 2, and 3 hepatitis C infection: a randomised, double-blind, phase 2 trial.
Infections
Sofosbuvir Plus Velpatasvir Combination Therapy for Treatment-Experienced Patients With Genotype 1 or 3 Hepatitis C Virus Infection: A Randomized Trial.
Infections
Soluble expression and enzymatic activity evaluation of protease from reticuloendotheliosis virus.
Infections
Solution structure and dynamics of C-terminal regulatory domain of Vibrio vulnificus extracellular metalloprotease.
Infections
Soybean trypsin inhibitor confers protection against rotavirus infection in infant mice.
Infections
Spatiotemporal expression of the putative MdtABC efflux pump of Phtotorhabdus luminescens occurs in a protease-dependent manner during insect infection.
Infections
Specific in vitro cleavage of Mason-Pfizer monkey virus capsid protein: evidence for a potential role of retroviral protease in early stages of infection.
Infections
Specific protease activity indicates the degree of Pseudomonas aeruginosa infection in chronic infected wounds.
Infections
Specification of type 2 innate lymphocytes by the transcriptional determinant Gfi1.
Infections
SPM1 encoding a vacuole-localized protease is required for infection-related autophagy of the rice blast fungus Magnaporthe oryzae.
Infections
STAT6 activation by Toxoplasma gondii infection induces the expression of Th2 C-C chemokine ligands and B clade serine protease inhibitors in macrophage.
Infections
Stem cell factor contributes to intestinal mucosal mast cell hyperplasia in rats infected with Nippostrongylus brasiliensis or Trichinella spiralis, but anti-stem cell factor treatment decreases parasite egg production during N brasiliensis infection.
Infections
Stem cell factor dependent hyperplasia of mucosal-type mast cells but not eosinophils in Schistosoma mansoni-infected rats.
Infections
Streptococcus pneumoniae serine protease HtrA, but not SFP or PrtA, is a major virulence factor in pneumonia.
Infections
Streptococcus pyogenes SpyCEP: a chemokine-inactivating protease with unique structural and biochemical features.
Infections
Structural and biochemical effects of human immunodeficiency virus mutants resistant to non-nucleoside reverse transcriptase inhibitors.
Infections
Structural and thermodynamic basis of resistance to HIV-1 protease inhibition: implications for inhibitor design.
Infections
Structural Basis for the Understanding of Entry Inhibitors Against SARS Viruses.
Infections
Structural evidence for regulation and specificity of flaviviral proteases and evolution of the Flaviviridae fold.
Infections
Structural properties of periplasmic SodCI that correlate with virulence in Salmonella enterica serovar Typhimurium.
Infections
Structure of West Nile virus NS3 protease: ligand stabilization of the catalytic conformation.
Infections
Studies on gonococcus infection. XVI. Purification of Neisseria gonorrhoeae immunoglobulin A1 protease.
Infections
Studies on gonococcus infection. XVII. IgA1-cleaving protease in vaginal washings from women with gonorrhea.
Infections
Subtype-associated differences in HIV-1 reverse transcription affect the viral replication.
Infections
Sulglycotide effect on the proteolytic and lipolytic activities of Helicobacter pylori toward gastric mucus.
Infections
Suppression of HIV-1 protease inhibitor resistance by phosphonate-mediated solvent anchoring.
Infections
Susceptibility of germ-free pigs to challenge with protease mutants of Salmonella enterica serovar Typhimurium.
Infections
Sustained viral response in a hepatitis C virus-infected chimpanzee via a combination of direct-acting antiviral agents.
Infections
Syndrome of lipodystrophy, hyperlipidemia, insulin resistance, and diabetes in treated patients with human immunodeficiency virus infection.
Infections
Synergistic anticryptosporidial potential of the combination alpha-1-antitrypsin and paromomycin.
Infections
Synergistic antiviral effect of PEG-asparaginase (ONCASPAR), with protease inhibitor alone and in combination with RT inhibitors against HIV-1 infected T-cells: a model of HIV-1-induced T-cell lymphoma.
Infections
Synergistic block of SARS-CoV-2 infection by combined drug inhibition of the host entry factors PIKfyve kinase and TMPRSS2 protease.
Infections
Synergistic effect of immune gamma-globulin fraction on protection by antibiotic against corneal ulcers in experimental mice infected with Pseudomonas aeruginosa.
Infections
Targeted disruption of SPI3/Serpinb6 does not result in developmental or growth defects, leukocyte dysfunction, or susceptibility to stroke.
Infections
Targeting metacaspase-3 from Plasmodium falciparum towards antimalarial therapy: A combined approach of in-silico and in-vitro investigation.
Infections
Tear Proteases and Protease Inhibitors: Potential Biomarkers and Disease Drivers in Ocular Surface Disease.
Infections
Telaprevir versus boceprevir in chronic hepatitis C: a meta-analysis of data from phase II and III trials.
Infections
Telaprevir-Induced Renal Adverse Events in Japanese Patients Reported in the PMDA Adverse Drug Reactions Reporting Database.
Infections
Tenofovir Alafenamide Versus Tenofovir Disoproxil Fumarate in the First Protease Inhibitor-Based Single-Tablet Regimen for Initial HIV-1 Therapy: A Randomized Phase 2 Study.
Infections
THE ABSENCE OF THYROID DISEASE IN AN AUSTRALIAN HEPATITIS C COHORT TREATED WITH TRIPLE COMBINATION THERAPY: A PARADIGM SHIFT.
Infections
The acute-phase protein response in parasite infection. Nippostrongylus brasiliensis and Trichinella spiralis in the rat.
Infections
The addition of a protease inhibitor increases the risk of infections in patients with hepatitis C-related cirrhosis.
Infections
The Anti-Inflammatory Immune Response in Early Trichinella spiralis Intestinal Infection Depends on Serine Protease Inhibitor-Mediated Alternative Activation of Macrophages.
Infections
The autophagic pathway is actively modulated by phase II Coxiella burnetii to efficiently replicate in the host cell.
Infections
The beginning of the end: What is the future of interferon therapy for chronic hepatitis C?
Infections
The Brucella abortus Lon functions as a generalized stress response protease and is required for wild-type virulence in BALB/c mice.
Infections
The changing face of Hepatitis C: Recent Advances on HCV Inhibitors Targeting NS5A.
Infections
The chloromethylketone protease inhibitor AAPF(CMK) also targets ATP-dependent helicases and SAP-domain proteins.
Infections
The contribution of key hydrophobic residues in ecotin to enzyme-inhibitor complex stability.
Infections
The cysteine protease ApdS from Streptococcus suis promotes evasion of innate immune defenses by cleaving the antimicrobial peptide cathelicidin LL-37.
Infections
The danish protease inhibitor study: a randomized study comparing the virological efficacy of 3 protease inhibitor-containing regimens for the treatment of human immunodeficiency virus type 1 infection.
Infections
The down-regulation of cathepsin G in THP-1 monocytes after infection with Mycobacterium tuberculosis is associated with increased intracellular survival of bacilli.
Infections
The duration of viral suppression during protease inhibitor therapy for HIV-1 infection is predicted by plasma HIV-1 RNA at the nadir.
Infections
The effect of HAART and HCV infection on the development of hyperglycemia among HIV-infected persons.
Infections
The effect of human immunodeficiency virus-1 protease inhibitors on the toxicity of a variety of cells.
Infections
The effect of infection with tobacco-mosaic virus on the levels of nitrogen, phosphorus, protease, and pectase in tobacco leaves and on their response to fertilizers.
Infections
The effect of protease inhibitor therapy on growth and body composition in human immunodeficiency virus type 1-infected children.
Infections
The effect of proteolytic enzymes and protease inhibitors on the interaction Trypanosoma cruzi-fibroblasts.
Infections
The effects of protease inhibitors and sugars on the survival and development of the parasite Onchocerca ochengi in its natural intermediate host Simulium damnosum s.l.
Infections
The electrophoretic mobility of alpha 1-antitrypsin in sputum and its relationship to protease inhibitory capacity, leucocyte elastase concentrations and acute respiratory infection.
Infections
The human mucus protease inhibitor and its mutants are novel defensive compounds against infection with influenza A and Sendai viruses.
Infections
The immune protection induced by a serine protease from the Trichinella spiralis adult against Trichinella spiralis infection in pigs.
Infections
The in vitro and ex vivo effect of Auranta 3001 in preventing Cryptosporidium hominis and Cryptosporidium parvum infection.
Infections
The ISG15/USP18 ubiquitin-like pathway (ISGylation system) in Hepatitis C Virus infection and resistance to interferon therapy.
Infections
The kdr-bearing haplotype and susceptibility to Plasmodium falciparum in Anopheles gambiae: genetic correlation and functional testing.
Infections
The Leishmania surface protease GP63 cleaves multiple intracellular proteins and actively participates in p38 mitogen-activated protein kinase inactivation.
Infections
The Lon-2 protease of Borrelia burgdorferi is critical for infection in the mammalian host.
Infections
The major head protein of bacteriophage T4 binds specifically to elongation factor Tu.
Infections
The majority of 9,729 group A streptococcus strains causing disease secrete SpeB cysteine protease: pathogenesis implications.
Infections
The molecular interplay of the establishment of an infection - gene expression of Diaphorina citri gut and Candidatus Liberibacter asiaticus.
Infections
The mosquito melanization response requires hierarchical activation of non-catalytic clip domain serine protease homologs.
Infections
The nitrogen content of the tomato leaf apoplast increases during infection by Cladosporium fulvum.
Infections
The phosphoproteomic responses of duck (Cairna moschata) to classical/novel duck reovirus infections in the spleen tissue.
Infections
The presence of resistance mutations to protease and polymerase inhibitors in Hepatitis C virus sequences from the Los Alamos databank.
Infections
The Probiotic Bacterium Phaeobacter inhibens Downregulates Virulence Factor Transcription in the Shellfish Pathogen Vibrio coralliilyticus by N-Acyl Homoserine Lactone Production.
Infections
THE PROTEASE LOCUS of FRANCISELLA TULARENSIS LVS IS REQUIRED FOR STRESS TOLERANCE AND INFECTION OF MAMMALIAN HOST.
Infections
The rabbit study: ritonavir and saquinavir in combination in saquinavir-experienced and previously untreated patients.
Infections
The remarkably multifunctional fibronectin binding proteins of Staphylococcus aureus.
Infections
The role of CCAAT enhancer-binding protein homologous protein in human immunodeficiency virus protease-inhibitor-induced hepatic lipotoxicity in mice.
Infections
The role of corticosteroid-binding globulin in the evaluation of adrenal insufficiency.
Infections
The role of non-nucleoside reverse transcriptase inhibitors (NNRTIs) in the therapy of HIV-1 infection.
Infections
The role of protease-dependent cell membrane fusion in persistent and lytic infections of murine hepatitis virus.
Infections
The role of secretory leucoprotease inhibitor in the resolution of inflammatory responses.
Infections
The Role of Vibrio cholerae Haemagglutinin Protease (HAP) in Extra-Intestinal Infection.
Infections
The Route of Infection Influences the Contribution of Key Immunity Genes to Antibacterial Defense in Anopheles gambiae.
Infections
The S100A10 Subunit of the Annexin A2 Heterotetramer Facilitates L2-Mediated Human Papillomavirus Infection.
Infections
The S1A protease family members CG10764 and CG4793 regulate cellular immunity in Drosophila.
Infections
The secretory leukocyte protease inhibitor (SLPI) and the secondary granule protein lactoferrin are synthesized in myelocytes, colocalize in subcellular fractions of neutrophils, and are coreleased by activated neutrophils.
Infections
The serine protease homolog CLIPA14 modulates the intensity of the immune response in the mosquito Anopheles gambiae.
Infections
The Successful Retreatment with Glecaprevir and Pibrentasvir of Genotype 1 or 2 HCV-infected Hemodialysis Patients who Failed to Respond to NS5A and Protease Inhibitor Treatment: A Case Report.
Infections
The Thrombotic Profile of Treatment-Naive HIV-Positive Black South Africans With Acute Coronary Syndromes.
Infections
The tissue factor pathway inhibitor 1 of Sciaenops ocellatus possesses antimicrobial activity and is involved in the immune response against bacterial infection.
Infections
The TMPRSS2 Inhibitor Nafamostat Reduces SARS-CoV-2 Pulmonary Infection in Mouse Models of COVID-19.
Infections
The use of cystatin C to inhibit epithelial-mesenchymal transition and morphological transformation stimulated by transforming growth factor-beta.
Infections
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Infections
Therapeutic effect of immunization with OEP, protease toxoid and elastase toxoid on corneal ulcers in mice due to Pseudomonas aeruginosa infection.
Infections
Therapeutic effects of benzoxazinorifamycin KRM-1648 administered alone or in combination with a half-sized secretory leukocyte protease inhibitor or the nonsteroidal anti-inflammatory drug diclofenac sodium against Mycobacterium avium complex infection in mice.
Infections
Thermodynamic basis of resistance to HIV-1 protease inhibition: calorimetric analysis of the V82F/I84V active site resistant mutant.
Infections
Thermodynamic rules for the design of high affinity HIV-1 protease inhibitors with adaptability to mutations and high selectivity towards unwanted targets.
Infections
Thrombospondin-1 restrains neutrophil granule serine protease function and regulates the innate immune response during Klebsiella pneumoniae infection.
Infections
Tipranavir in highly antiretroviral treatment-experienced patients: Results from a French prospective cohort.
Infections
Tipranavir resistance associated mutations in protease inhibitor-naïve patients with HIV-1 subtype A/E infection.
Infections
Tissue factor and glycoprotein C on herpes simplex virus type 1 are protease activated receptor 2 cofactors that enhance infection.
Infections
Tissue plasminogen activator to prevent central venous access device infections: a systematic review of central venous access catheter thrombosis, infection and thromboprophylaxis.
Infections
TMPRSS11A activates the influenza A virus hemagglutinin and the MERS coronavirus spike protein and is insensitive against blockade by HAI-1.
Infections
TMPRSS2 activates the human coronavirus 229E for cathepsin-independent host cell entry and is expressed in viral target cells in the respiratory epithelium.
Infections
Tn5-induced protease-deficient strains of Aeromonas hydrophila with reduced virulence for fish.
Infections
Tolerance and responsive gene expression of Sogatella furcifera under extreme temperature stresses are altered by its vectored plant virus.
Infections
Toward the physiological basis for increased Agrotis ipsilon multiple nucleopolyhedrovirus infection following feeding of Agrotis ipsilon larvae on transgenic corn expressing Cry1Fa2.
Infections
Towards tricking a pathogen's protease into fighting infection: the 3D structure of a stable circularly permuted onconase variant cleavedby HIV-1 protease.
Infections
Toxoid construction of AsaP1, a lethal toxic aspzincin metalloendopeptidase of Aeromonas salmonicida subsp. achromogenes, and studies of its activity and processing.
Infections
Toxoplasma Cathepsin Protease B and Aspartyl Protease 1 Are Dispensable for Endolysosomal Protein Digestion.
Infections
Transcriptional and secretory responses of Entamoeba histolytica to mucins, epithelial cells and bacteria.
Infections
Transcriptome analysis of the entomopathogenic fungus Beauveria bassiana grown on cuticular extracts of the coffee berry borer (Hypothenemus hampei).
Infections
Transcriptomic analysis of oligochaete immune responses to myxosporeans infection: Branchiura sowerbyi infected with Myxobolus cultus.
Infections
Transformation of glycerate kinase (GLYK) into Metarhizium acridum increases virulence to locust.
Infections
Transmitted Drug Resistance Mutations in Antiretroviral-Naïve Injection Drug Users with Chronic HIV-1 Infection in Iran.
Infections
Treatment failure and resistance with direct acting antiviral drugs against hepatitis C virus.
Infections
Treatment history and baseline viral load, but not viral tropism or CCR-5 genotype, influence prolonged antiviral efficacy of highly active antiretroviral treatment.
Infections
Treatment of hepatitis C virus infection in adults and children: updated Swedish consensus recommendations.
Infections
Treatment outcomes after highly active antiretroviral therapy: a meta-analysis of randomised controlled trials.
Infections
Treatment strategy against infection: clinical outcome of continuous regional arterial infusion, enteral nutrition, and surgery in severe acute pancreatitis.
Infections
Treatment with Exogenous Trypsin Expands In Vitro Cellular Tropism of the Avian Coronavirus Infectious Bronchitis Virus.
Infections
Treatment with protease inhibitors associated with peripheral insulin resistance and impaired oral glucose tolerance in HIV-1-infected patients.
Infections
Triple-nucleoside regimens versus efavirenz-containing regimens for the initial treatment of HIV-1 infection.
Infections
Tritherapy for human immunodeficiency virus infection does not modify replication of hepatitis C virus in coinfected subjects.
Infections
Truncation of a P1 leader proteinase facilitates potyvirus replication in a non-permissive host.
Infections
Trypanosoma cruzi-fibroblastic cell interactions necessary for cellular invasion.
Infections
Trypanosoma cruzi: enhanced alpha-macroglobulin levels correlate with the resistance of BALB/cj mice to acute infection.
Infections
Trypanosoma cruzi: inhibition of host cell uptake of infective bloodstream forms by alpha-2-macroglobulin.
Infections
Tsetse GmmSRPN10 has anti-complement activity and is important for successful establishment of trypanosome infections in the fly midgut.
Infections
Tuberculosis, onychomycosis and immune deficiency in complicated Crohn's disease.
Infections
Two mutants of human heparin binding protein (CAP37): toward the understanding of the nature of lipid A/LPS and BPTI binding.
Infections
Two patients treated with pegylated interferon/ribavirin/telaprevir triple therapy for recurrent hepatitis C after living donor liver transplantation.
Infections
Type I interferon remodels lysosome function and modifies intestinal epithelial defense.
Infections
Type II Secretion-Dependent Aminopeptidase LapA and Acyltransferase PlaC Are Redundant for Nutrient Acquisition during Legionella pneumophila Intracellular Infection of Amoebas.
Infections
UK consensus guidelines for the use of the protease inhibitors boceprevir and telaprevir in genotype 1 chronic hepatitis C infected patients.
Infections
Ultrasound evaluation of perihepatic lymph nodes during antiviral therapy with the protease inhibitor telaprevir (VX-950) in patients with chronic hepatitis C infection.
Infections
Uncovering targets of the Leader protease: Linking RNA-mediated pathways and antiviral defense.
Infections
Unexploited viral and host targets for the treatment of human immunodeficiency virus type 1 infection.
Infections
Unique Flap Conformation in an HIV-1 Protease with High-Level Darunavir Resistance.
Infections
Unique thermodynamic response of tipranavir to human immunodeficiency virus type 1 protease drug resistance mutations.
Infections
Unraveling the Impact of Secreted Proteases on Hypervirulence in Staphylococcus aureus.
Infections
Unusual Response of Subclavian In-Stent Restenosis to Balloon Angioplasty in a Patient with HIV.
Infections
Updated guidelines for the use of rifabutin or rifampin for the treatment and prevention of tuberculosis among HIV-infected patients taking protease inhibitors or nonnucleoside reverse transcriptase inhibitors.
Infections
UPLC-MS/MS method with automated on-line SPE for the isomer-specific quantification of the first-generation anti-HCV protease inhibitors in peripheral blood mononuclear cells.
Infections
Use of an emollient-containing diaper and pH-buffered wipe regimen restores skin pH and reduces residual enzymatic activity.
Infections
Use of recombinase-based in vivo expression technology to characterize Enterococcus faecalis gene expression during infection identifies in vivo-expressed antisense RNAs and implicates the protease Eep in pathogenesis.
Infections
USP19 suppresses cellular type I interferon signaling by targeting TRAF3 for deubiquitination.
Infections
USP4 positively regulates RLR-induced NF-?B activation by targeting TRAF6 for K48-linked deubiquitination and inhibits enterovirus 71 replication.
Infections
Vaccine targeting SIVmac251 protease cleavage sites protects macaques against vaginal infection.
Infections
Vaccinia virus serpins B13R (SPI-2) and B22R (SPI-1) encode M(r) 38.5 and 40K, intracellular polypeptides that do not affect virus virulence in a murine intranasal model.
Infections
Validation and application of a high-performance liquid chromatography-tandem mass spectrometric method for simultaneous quantification of lopinavir and ritonavir in human plasma using semi-automated 96-well liquid-liquid extraction.
Infections
Vascular permeability enhancement by Vibrio mimicus protease and the mechanisms of action.
Infections
Vesicular trafficking of incoming human papillomavirus 16 to the Golgi apparatus and endoplasmic reticulum requires ?-secretase activity.
Infections
Vibrio vulnificus secretes a broad-specificity metalloprotease capable of interfering with blood homeostasis through prothrombin activation and fibrinolysis.
Infections
Viral fibroblast growth factor, matrix metalloproteases, and caspases are associated with enhancing systemic infection by baculoviruses.
Infections
Viro-immunological efficacy and tolerability of dolutegravir-based regimens compared to regimens based on other integrase strand inhibitors, protease inhibitors or non-nucleoside reverse transcriptase inhibitors in patients with acute HIV-1 infection: A multicenter retrospective cohort study.
Infections
Virological and immunological outcomes at 3 years after starting antiretroviral therapy with regimens containing non-nucleoside reverse transcriptase inhibitor, protease inhibitor, or both in INITIO: open-label randomised trial.
Infections
Virological failure in patients with HIV-1 subtype C receiving antiretroviral therapy: an analysis of a prospective national cohort in Sweden.
Infections
Virulence factors and drug resistance in Escherichia coli isolated from extraintestinal infections.
Infections
VISLISI trial, a prospective clinical study allowing identification of a new metalloprotease and putative virulence factor from Staphylococcus lugdunensis.
Infections
Von Willebrand Factor Adhesive Activity and ADAMTS13 Protease Activity in HIV-1-Infected Men.
Infections
War and peace between WAP and HIV: role of SLPI, trappin-2, elafin and ps20 in susceptibility to HIV infection.
Infections
Wide Proteolytic Activity Survey Reinforces Heterogeneity Among Trypanosoma cruzi TCI and TCII Wild Populations.
Infections
Yersinia enterocolitica YopT and Clostridium difficile toxin B induce expression of GILZ in epithelial cells.
Infections
[A case of bacteremic group A streptococcus infection with organ dysfunction following a minor skin abrasion]
Infections
[A review on the role of angiotensin-converting enzyme 2 in children with coronavirus disease 2019].
Infections
[Antiretroviral therapy for HIV-infected patients with schizophrenia. Coordinated multidisciplinary management (7 cases)]
Infections
[Can SARS-CoV-2 infect the eye?-An overview of the receptor status in ocular tissue].
Infections
[Characteristics of protein hydrolysis on the digestive-transport surfaces of the intestine of the kittiwake Rissa tridactyla and Alcataenia larina (Cestoda, Dilepididae) parasitizing it].
Infections
[Clinical trial comparing efficacy and safety of four highly active antiretroviral therapy (HAART) in antiretroviral-naive treatment with advanced HIV infection.]
Infections
[Contemporary therapy of chronic obstructive pulmonary disease and its new directions]
Infections
[Correlation between HIV-inhibiting drug activity in human macrophages and clinical outcome]
Infections
[Diagnosis, treatment, and follow-up of hepatitis C-virus related liver disease. Hungarian national consensus guideline].
Infections
[Differential expression of apoptosis-related gene induced by clinical and laboratory Mycobacterium tuberculosis strain in macrophages U937 revealed by oligonucleotide microarray]
Infections
[Effect of multi-generation culture on virulence of Lecanicilliurn lecanii in different media]
Infections
[Effects of an antiserum prepared against purified protease of pseudomonas aeruginosa (authors transl)]
Infections
[Effects of half-sized secretory leukocyte protease inhibitor and Chinese traditional medicines, yokuinin and mao-bushi-saishin-to, on therapeutic efficacies of benzoxazinorifamycin KRM-1648 against Mycobacterium avium complex infection induced in mice]
Infections
[Effects of secretory leukocyte protease inhibitor on the production of some cytokines and nitric oxide by murine peritoneal macrophages in response to lipopolysaccharide stimulation and M. avium complex infection]
Infections
[Efficacy and safety of a protease inhibitor with pegylated interferon and ribavirin in patients with untreated chronic hepatitis C: a meta analysis].
Infections
[Expert opinion on boceprevir- and telaprevir-based triple therapies of chronic hepatitis C].
Infections
[Factors associated with an abnormal ankle-braquial index in a cohort of patients with HIV-1 infection.]
Infections
[Flow cytometry detection of erythrocyte antigens and antibodies. Technical aspects and new clinical applications]
Infections
[HIV infection. Compatibility of recent protease inhibitors in direct comparison - the advantage of DRV].
Infections
[HIV-1 therapy in the Netherlands; virological and immunological response to antiretroviral therapy]
Infections
[Hungarian consensus guideline for the diagnosis and treatment of B, C, and D viral hepatitis].
Infections
[Importance of antiproteases in the treatment of microsporidia and/or cryptosporidia infections in HIV-seropositive patients]
Infections
[Influence of plasmid pR50 controlling bacterial protease activity on Salmonella experimental infection]
Infections
[Intestinal parasitic infections and leishmaniasis in patients with HIV infection]
Infections
[Localization and activity of different lysosomal proteases in rat macrophages infected by Leishmania amazonensis]
Infections
[Lopinavir/ritonavir in patients with human immunodeficiency virus infection in special situations].
Infections
[Mechanism behind streptococcus toxic shock-like syndrome onset--immune evasion and bacterial properties]
Infections
[Molecular mechanism of replication and transcription of the influenza virus genome and host factors]
Infections
[Mycobacterium avium complex disease in HIV seropositive patients: incidence and risk factors before and after the introduction of highly active antiretroviral treatments. Clinical Epidemiology Group of the Information and Care Center for Human Immunodeficiency]
Infections
[Myocardial infarction in the course of antiretroviral therapy with protease inhibitor]
Infections
[Pathogenic effect of pandemic influenza virus H1N1 under replication in cultures of human cells].
Infections
[Plasma levels of mannan-binding lectin-associated serine protease 2 in children with upper respiratory tract infection].
Infections
[Progress in researches of molecular mechanism of schistosome cercariae infection].
Infections
[Recent development of novel reverse transcriptase inhibitors and protease inhibitors against HIV-1 infection]
Infections
[Ribosomal Protein S9 Expression in Multiple Myeloma and Its Effect on Cell Biological Function].
Infections
[The maturation steps of human immunodeficiency virus and the role of proteolysis]
Infections
[The protease inhibitor gabexate mesilate in experimentally-induced acute pancreatitis with early gram-negative infection in the Göttingen minipig: therapeutic efficacy and effects on blood coagulation and fibrinolysis]
Infections
[Therapeutic attitude to HIV infection: uncertain and variable scientific attitudes. 1998 national survey of physicians prescribing antiretroviral drugs]
Infertility
Acrosin antibodies and infertility. I. Detection of antibodies towards proacrosin/acrosin in women consulting for infertility and evaluation of their effects upon the sperm protease activities.
Infertility
Association between ubiquitin-specific protease USP26 polymorphism and male infertility in Chinese men.
Infertility
Binding of human secretory leukocyte protease inhibitor in uterine cervical mucus to immunoglobulins: pathophysiology in immunologic infertility and local immune defense.
Infertility
Evaluation of the levels of secretory leukocyte protease inhibitor in the cervical mucus of women with unexplained infertility.
Infertility
Mutation in the protease cleavage site of GDF9 increases ovulation rate and litter size in heterozygous ewes and causes infertility in homozygous ewes.
Infertility
The Wilms tumor protein Wt1 contributes to female fertility by regulating oviductal proteostasis.
Infertility
Ubiquitin-specific protease activity of USP9Y, a male infertility gene on the Y chromosome.
Infertility, Female
Disruption of the ovarian serine protease (Osp) gene causes female sterility in Bombyx mori and Spodoptera litura.
Infertility, Male
Association between ubiquitin-specific protease USP26 polymorphism and male infertility in Chinese men.
Infertility, Male
Association of 370-371insACA, 494T>C, and 1423C>T haplotype in ubiquitin-specific protease 26 gene and male infertility: a meta-analysis.
Infertility, Male
Efficient production of genetically engineered, male-sterile Arabidopsis thaliana using anther-specific promoters and genes derived from Brassica oleracea and B. rapa.
Infertility, Male
Haplotypes, mutations and male fertility: the story of the testis-specific ubiquitin protease USP26.
Infertility, Male
Immune mediators associated to male infertility in a mouse model of DNA immunization with the sperm protease proacrosin.
Infertility, Male
Mutation of the seminal protease gene, serine protease 2, results in male sterility in diverse lepidopterans.
Infertility, Male
Novel mutations in testis-specific ubiquitin protease 26 gene may cause male infertility and hypogonadism.
Infertility, Male
Novel mutations in ubiquitin-specific protease 26 gene might cause spermatogenesis impairment and male infertility.
Infertility, Male
Sequence analysis of the X-linked USP26 gene in severe male factor infertility patients and fertile controls.
Infertility, Male
Sperm Proteome Analysis and Identification of Fertility-Associated Biomarkers in Unexplained Male Infertility.
Infertility, Male
Targeted Gene Deletion and Phenotypic Analysis of the Drosophila melanogaster Seminal Fluid Protease Inhibitor Acp62F.
Infertility, Male
Ubiquitin-specific protease (USP26) gene alterations associated with male infertility and recurrent pregnancy loss (RPL) in Iranian infertile patients.
Infertility, Male
Ubiquitin-specific protease activity of USP9Y, a male infertility gene on the Y chromosome.
Infertility, Male
[Study on the association of USP8 gene polymorphisms with male infertility in ethnic Han Chinese from Sichuan].
Inflammatory Bowel Diseases
A low dose of fermented soy germ alleviates gut barrier injury, hyperalgesia and faecal protease activity in a rat model of inflammatory bowel disease.
Inflammatory Bowel Diseases
Alpha1-antitrypsin alleles and phenotypes in patients with inflammatory bowel disease.
Inflammatory Bowel Diseases
Application of a chemical probe to detect neutrophil elastase activation during inflammatory bowel disease.
Inflammatory Bowel Diseases
Collagenase-3 (MMP-13) expression by inflamed mucosa in inflammatory bowel disease.
Inflammatory Bowel Diseases
Fecal Serine Protease Profiling in Inflammatory Bowel Diseases.
Inflammatory Bowel Diseases
Genetic evidence supporting the association of protease and protease inhibitor genes with inflammatory bowel disease: a systematic review.
Inflammatory Bowel Diseases
Genetic markers and inflammatory bowel disease: immunoglobulin allotypes (GM, KM) and protease inhibitor.
Inflammatory Bowel Diseases
Influence of the Treatment Used in Inflammatory Bowel Disease on the Protease Activities.
Inflammatory Bowel Diseases
Intestinal Protease-Activated Receptor-2 and Fecal Serine Protease Activity are Increased in Canine Inflammatory Bowel Disease and May Contribute to Intestinal Cytokine Expression.
Inflammatory Bowel Diseases
MALT1 inhibitors prevent the development of DSS-induced experimental colitis in mice via inhibiting NF-?B and NLRP3 inflammasome activation.
Inflammatory Bowel Diseases
New Peptide Inhibitor of Dipeptidyl Peptidase IV, EMDB-1 Extends the Half-Life of GLP-2 and Attenuates Colitis in Mice after Topical Administration.
Inflammatory Bowel Diseases
Novel peptide inhibitor of dipeptidyl peptidase IV (Tyr-Pro-D-Ala-NH2) with anti-inflammatory activity in the mouse models of colitis.
Inflammatory Bowel Diseases
Protease inhibitors in plasma and faecal extracts from patients with active inflammatory bowel disease.
Inflammatory Bowel Diseases
Release of mast cell tryptase from human colorectal mucosa in inflammatory bowel disease.
Inflammatory Bowel Diseases
Role of meprins to protect ileal mucosa of Crohn's disease patients from colonization by adherent-invasive E. coli.
Inflammatory Bowel Diseases
Serum Dipeptidyl Peptidase 4: A Predictor of Disease Activity and Prognosis in Inflammatory Bowel Disease.
Inflammatory Bowel Diseases
Siropins, novel serine protease inhibitors from gut microbiota acting on human proteases involved in inflammatory bowel diseases.
Inflammatory Bowel Diseases
The molecular biology of matrix metalloproteinases and tissue inhibitors of metalloproteinases in inflammatory bowel diseases.
Inflammatory Bowel Diseases
The stable gastric pentadecapeptide BPC 157, given locally, improves CO2 laser healing in mice.
Inflammatory Bowel Diseases
TNF?-antagonist use and mucosal inflammation are associated with increased intestinal expression of SARS-CoV-2 host protease TMPRSS2 in patients with inflammatory bowel disease.
Inflammatory Bowel Diseases
Ulcerative colitis, Crohn's disease, and irritable bowel syndrome have different profiles of extracellular matrix turnover, which also reflects disease activity in Crohn's disease.
Influenza in Birds
Establishment of MDCK Stable Cell Lines Expressing TMPRSS2 and MSPL and Their Applications in Propagating Influenza Vaccine Viruses in Absence of Exogenous Trypsin.
Influenza in Birds
Hemagglutinin activation of pathogenic avian influenza viruses of serotype H7 requires the protease recognition motif R-X-K/R-R.
Influenza in Birds
Hemagglutinins of avian influenza viruses are proteolytically activated by TMPRSS2 in human and murine airway cells.
Influenza in Birds
Identification of inhibitors using a cell-based assay for monitoring Golgi-resident protease activity.
Influenza in Birds
Importance of conserved amino acids at the cleavage site of the haemagglutinin of a virulent avian influenza A virus.
Influenza in Birds
Insertions of codons encoding basic amino acids in H7 hemagglutinins of influenza A viruses occur by recombination with RNA at hotspots near snoRNA binding sites.
Influenza in Birds
Peptidomimetic furin inhibitor MI-701 in combination with oseltamivir and ribavirin efficiently blocks propagation of highly pathogenic avian influenza viruses and delays high level oseltamivir resistance in MDCK cells.
Influenza in Birds
Protease activation mutants elicit protective immunity against highly pathogenic avian influenza viruses of subtype H7 in chickens and mice.
Influenza in Birds
Replication of a low-pathogenic avian influenza virus is enhanced by chicken ubiquitin-specific protease 18.
Influenza in Birds
The potential of a protease activation mutant of a highly pathogenic avian influenza virus for a pandemic live vaccine.
Influenza, Human
A Mutant H3N2 Influenza Virus Uses an Alternative Activation Mechanism in TMPRSS2 Knockout Mice by Loss of an Oligosaccharide in the Hemagglutinin Stalk Region.
Influenza, Human
A peptide-based approach to evaluate the adaptability of influenza A virus to humans based on its hemagglutinin proteolytic cleavage site.
Influenza, Human
Activation of influenza A viruses by host proteases from swine airway epithelium.
Influenza, Human
Airway protease/antiprotease imbalance in atopic asthmatics contributes to increased Influenza A virus cleavage and replication.
Influenza, Human
Airway proteases: an emerging drug target for influenza and other respiratory virus infections.
Influenza, Human
Alternaria alternata Accelerates Loss of Alveolar Macrophages and Promotes Lethal Influenza A Infection.
Influenza, Human
Amino acid residues in the N-terminal region of the PA subunit of influenza A virus RNA polymerase play a critical role in protein stability, endonuclease activity, cap binding, and virion RNA promoter binding.
Influenza, Human
An enzymatic virus-like particle assay for sensitive detection of virus entry.
Influenza, Human
Approach to the involvement of influenza B neuraminidase in the cleavage of HA by host cell protease using low pH-induced cell fusion reaction.
Influenza, Human
Aprotinin, a protease inhibitor, suppresses proteolytic activation of pandemic H1N1v influenza virus.
Influenza, Human
AR-12 Inhibits Multiple Chaperones Concomitant With Stimulating Autophagosome Formation Collectively Preventing Virus Replication.
Influenza, Human
Characterization of innate responses to influenza virus infection in a novel lung type I epithelial cell model.
Influenza, Human
Cleavage of influenza A virus H1 hemagglutinin by swine respiratory bacterial proteases.
Influenza, Human
Cleavage of influenza virus hemagglutinin by airway proteases TMPRSS2 and HAT differs in subcellular localization and susceptibility to protease inhibitors.
Influenza, Human
Comparative inhibitory effects of various nucleoside and nonnucleoside analogues on replication of influenza virus types A and B in vitro and in ovo.
Influenza, Human
Comparison of antigen presentation of influenza A nucleoprotein expressed in attenuated AroA- Salmonella typhimurium with that of live virus.
Influenza, Human
Coumarins and Quinolones as Effective Multiple Targeted Agents Versus Covid-19: An in Silico Study.
Influenza, Human
Differentiated swine airway epithelial cell cultures for the investigation of influenza A virus infection and replication.
Influenza, Human
Effect of a plant polyphenol-rich extract on the lung protease activities of influenza-virus-infected mice.
Influenza, Human
Effects of the protonation state of the catalytic residues and ligands upon binding and recognition in targeted proteins of HIV-1 and influenza viruses.
Influenza, Human
Endogenous expression of proteases in colon cancer cells facilitate influenza A viruses mediated oncolysis.
Influenza, Human
Endogenous protease-dependent replication of human influenza viruses in two MDCK cell lines.
Influenza, Human
Energy metabolic disorder is a major risk factor in severe influenza virus infection: Proposals for new therapeutic options based on animal model experiments.
Influenza, Human
Establishment of retroviral pseudotypes with influenza hemagglutinins from H1, H3, and H5 subtypes for sensitive and specific detection of neutralizing antibodies.
Influenza, Human
Evaluation of anti-influenza effects of camostat in mice infected with non-adapted human influenza viruses.
Influenza, Human
Evolutionary mechanisms involved in the virulence of infectious salmon anaemia virus (ISAV), a piscine orthomyxovirus.
Influenza, Human
Expression of Factor X in BHK-21 Cells Promotes Low Pathogenic Influenza Viruses Replication.
Influenza, Human
Expression of influenza B virus hemagglutinin containing multibasic residue cleavage sites.
Influenza, Human
Extracellular processing of peptide antigens that bind class I major histocompatibility molecules.
Influenza, Human
First genome report and analysis of chicken H7N9 influenza viruses with poly-basic amino acids insertion in the hemagglutinin cleavage site.
Influenza, Human
Frequency, specificity, and sites of expansion of CD8+ T cells during primary pulmonary influenza virus infection.
Influenza, Human
Generation of seal influenza virus variants pathogenic for chickens, because of hemagglutinin cleavage site changes.
Influenza, Human
Genotypic analysis of plasma HIV-1 RNA after influenza vaccination of patients with previously undetectable viral loads.
Influenza, Human
Hemagglutinins of avian influenza viruses are proteolytically activated by TMPRSS2 in human and murine airway cells.
Influenza, Human
Human mucus protease inhibitor in airway fluids is a potential defensive compound against infection with influenza A and Sendai viruses.
Influenza, Human
Identification of ovarian genes regulated by follicle-stimulating hormone (Fsh) in vitro during early secondary oocyte growth in coho salmon.
Influenza, Human
Identification of trypsin I as a candidate for influenza A virus and Sendai virus envelope glycoprotein processing protease in rat brain.
Influenza, Human
Influenza and SARS-coronavirus activating proteases TMPRSS2 and HAT are expressed at multiple sites in human respiratory and gastrointestinal tracts.
Influenza, Human
Influenza virus and proteolytic bacteria co-infection in respiratory tract from individuals presenting respiratory manifestations.
Influenza, Human
Influenza Virus H1N1 inhibition by serine protease inhibitor (serpin) antithrombin III.
Influenza, Human
Influenza virus RNA polymerase PA subunit is a novel serine protease with Ser624 at the active site.
Influenza, Human
Influenza virus-cytokine-protease cycle in the pathogenesis of vascular hyperpermeability in severe influenza.
Influenza, Human
Inhibition of Influenza A virus propagation by benzoselenoxanthenes stabilizing TMPRSS2 Gene G-quadruplex and hence down-regulating TMPRSS2 expression.
Influenza, Human
Inhibition of influenza virus infection and hemagglutinin cleavage by the protease inhibitor HAI-2.
Influenza, Human
Inhibition of influenza virus infection in human airway cell cultures by an antisense peptide-conjugated morpholino oligomer targeting the hemagglutinin-activating protease TMPRSS2.
Influenza, Human
Inhibition of lung serine proteases in mice: a potentially new approach to control influenza infection.
Influenza, Human
Inhibition of the protease activity of influenza virus RNA polymerase PA subunit by viral matrix protein.
Influenza, Human
Inhibitory effect of a protease inhibitor, leupeptin, on the development of influenza pneumonia, mediated by concomitant bacteria.
Influenza, Human
Internal proteins of influenza virus: 35S-methionine peptide maps as genetic markers.
Influenza, Human
Kallikrein-Related Peptidase 5 Contributes to H3N2 Influenza Virus Infection in Human Lungs.
Influenza, Human
Kallistatin ameliorates influenza virus pathogenesis by inhibition of kallikrein-related peptidase 1-mediated cleavage of viral hemagglutinin.
Influenza, Human
Mammalian expression of virus-like particles for advanced mimicry of authentic influenza virus.
Influenza, Human
MDCK cells that express proteases TMPRSS2 and HAT provide a cell system to propagate influenza viruses in the absence of trypsin and to study cleavage of HA and its inhibition.
Influenza, Human
MicroRNA regulation of human protease genes essential for influenza virus replication.
Influenza, Human
Mini-plasmin found in the epithelial cells of bronchioles triggers infection by broad-spectrum influenza A viruses and Sendai virus.
Influenza, Human
Modulation of airway smooth muscle tone by protease activated receptor-1,-2,-3 and -4 in trachea isolated from influenza A virus-infected mice.
Influenza, Human
Molecular architecture and activation of the insecticidal protein Vip3Aa from Bacillus thuringiensis.
Influenza, Human
Molecular mechanism of complex infection by bacteria and virus analyzed by a model using serratial protease and influenza virus in mice.
Influenza, Human
Myxovirus replication in chicken embryos can be suppressed by aprotinin due to the blockage of viral glycoprotein cleavage.
Influenza, Human
Non-human primate orthologues of TMPRSS2 cleave and activate the influenza virus hemagglutinin.
Influenza, Human
Phenotypic mixing with recombinant haemagglutinin of high cleavability mediates multi-cycle replication of human influenza virus in cell culture.
Influenza, Human
Potentiation of infectivity and pathogenesis of influenza A virus by a house dust mite protease.
Influenza, Human
Proteases essential for human influenza virus entry into cells and their inhibitors as potential therapeutic agents.
Influenza, Human
Proteasomal Serine Hydrolases Are Up-Regulated by and Required for Influenza Virus Infection.
Influenza, Human
Protective effect of protease inhibitors in influenza virus infected animals.
Influenza, Human
Proteolytic activation of influenza viruses by serine proteases TMPRSS2 and HAT from human airway epithelium.
Influenza, Human
Recombinant protein susceptibility to proteolysis in the plant cell secretory pathway is pH-dependent.
Influenza, Human
Respiratory protease/antiprotease balance determines susceptibility to viral infection and can be modified by nutritional antioxidants.
Influenza, Human
Respiratory syncytial virus (RSV) entry is inhibited by serine protease inhibitor AEBSF when present during an early stage of infection.
Influenza, Human
Role of host trypsin-type serine proteases and influenza virus-cytokine-trypsin cycle in influenza viral pathogenesis. Pathogenesis-based therapeutic options.
Influenza, Human
Ser624 of the PA subunit of influenza A virus is not essential for viral growth in cells and mice, but required for the maximal viral growth.
Influenza, Human
Sialidase and protease activities of commercial (RDE) receptor destroying enzyme products used for the (HI) hemagglutination inhibition test of influenza viruses]
Influenza, Human
SPINT2 inhibits proteases involved in activation of both influenza viruses and metapneumoviruses.
Influenza, Human
Suppression of glycoprotein formation of Semliki Forest, influenza, and avian sarcoma virus by tunicamycin.
Influenza, Human
Suppression of influenza virus replication in infected mice by protease inhibitors.
Influenza, Human
Synergistic inhibition of influenza A virus replication by a plant polyphenol-rich extract and epsilon-aminocaproic acid in vitro and in vivo.
Influenza, Human
Synergistic role of staphylococcal proteases in the induction of influenza virus pathogenicity.
Influenza, Human
The clinically used serine protease inhibitor nafamostat reduces influenza virus replication and cytokine production in human airway epithelial cells and viral replication in mice.
Influenza, Human
The Current Recommended Drugs and Strategies for the Treatment of Coronavirus Disease (COVID-19).
Influenza, Human
The effect of protease treatment on the morphology of influenza A, B and C viruses.
Influenza, Human
The host protease TMPRSS2 plays a major role for in vivo replication of emerging H7N9 and seasonal influenza viruses.
Influenza, Human
The human mucus protease inhibitor and its mutants are novel defensive compounds against infection with influenza A and Sendai viruses.
Influenza, Human
The proteolytic activation of A (H3N2) Influenza virus hemagglutinin is facilitated by different type II transmembrane serine proteases.
Influenza, Human
The serine protease inhibitor camostat inhibits influenza virus replication and cytokine production in primary cultures of human tracheal epithelial cells.
Influenza, Human
Threonine 157 of influenza virus PA polymerase subunit modulates RNA replication in infectious viruses.
Influenza, Human
TMPRSS2 and TMPRSS4 facilitate trypsin-independent spread of influenza virus in Caco-2 cells.
Influenza, Human
TMPRSS2 Independency for Haemagglutinin Cleavage In Vivo Differentiates Influenza B Virus from Influenza A Virus.
Influenza, Human
TMPRSS2 Is a Host Factor That Is Essential for Pneumotropism and Pathogenicity of H7N9 Influenza A Virus in Mice.
Influenza, Human
TMPRSS2 is the major activating protease of influenza A virus in primary human airway cells and influenza B virus in human type II pneumocytes.
Influenza, Human
TMPRSS2 Isoform 1 Activates Respiratory Viruses and Is Expressed in Viral Target Cells.
Influenza, Human
Tmprss2 knock-out mice are resistant to H10 influenza A virus pathogenesis.
Influenza, Human
TMPRSS2: A potential target for treatment of influenza virus and coronavirus infections.
Influenza, Human
Transcriptome profiling and protease inhibition experiments identify proteases that activate H3N2 influenza A and influenza B viruses in murine airways.
Influenza, Human
Truncated forms of the PA protein containing only the C-terminal domains are associated with the RNP complex within H1N1 influenza virus particles.
Influenza, Human
Tumorigenic potential of human fibroblasts as a function of ability to express a novel form of influenza A nucleocapsid protein.
Influenza, Human
White button mushroom interrupts tissue AR-mediated TMPRSS2 expression and attenuates pro-inflammatory cytokines in C57BL/6 mice.
Influenza, Human
[Antiviral and therapeutic action of protease inhibitors in viral infections: experimental and clinical observations]
Influenza, Human
[Changes in the protease activity in the lungs of mice infected with the influenza A virus]
Influenza, Human
[Identification of the protease-binding domain in the N-terminal region of the influenza A virus matrix protein M1]
Influenza, Human
[Participation of the proteolysis system in promoting the virulence of the influenza virus and development of the infectious process; the antiviral effect of protease inhibitors]
Influenza, Human
[Pathogenic effect of pandemic influenza virus H1N1 under replication in cultures of human cells].
Influenza, Human
[Protease inhibitor suppression of influenza virus replication in the lungs of infected mice]
Influenza, Human
[Protease inhibitors block the spread of the influenza virus in the body of infected animals]
Influenza, Human
[Proteolytic mechanism of deproteinization of influenza virus by plasmatic membranes]
Influenza, Human
[The pathogenetic therapy of acute respiratory diseases by aprotinin inhalations]
Influenza, Human
[The role of cleavage activation of the hemagglutinin by host and bacterial proteases in the induction of the pathogenesis of influenza viruses]
Insomnia, Fatal Familial
Diagnosis of prion diseases by RT-QuIC results in improved surveillance.
Insulin Resistance
A New Hypothesis for Insulin Resistance in Hypertension Due to Receptor Cleavage.
Insulin Resistance
A randomized comparative 96-week trial of boosted atazanavir versus continued boosted protease inhibitor in HIV-1 patients with abdominal adiposity.
Insulin Resistance
A single centre cohort experience with a new once daily antiretroviral drug.
Insulin Resistance
A syndrome of lipoatrophy, lactic acidaemia and liver dysfunction associated with HIV nucleoside analogue therapy: contribution to protease inhibitor-related lipodystrophy syndrome.
Insulin Resistance
AACTG recommendations for metabolic problems. Guide covers insulin resistance and diabetes.
Insulin Resistance
Abnormal lipids and the acquired immunodeficiency syndrome: is there a problem and what should we do about it?
Insulin Resistance
Acanthosis nigricans: a new manifestation of insulin resistance in patients receiving treatment with protease inhibitors.
Insulin Resistance
Adipocyte dysfunction in response to antiretroviral therapy: clinical, tissue and in-vitro studies.
Insulin Resistance
Adverse metabolic consequences of HIV protease inhibitor therapy: the search for a central mechanism.
Insulin Resistance
Alterations in thigh subcutaneous adipose tissue gene expression in protease inhibitor-based highly active antiretroviral therapy.
Insulin Resistance
Antiretroviral therapy as a cardiovascular disease risk factor: fact or fiction? A review of clinical and surrogate outcome studies.
Insulin Resistance
Antiretroviral treatment reduces very-low-density lipoprotein and intermediate-density lipoprotein apolipoprotein B fractional catabolic rate in human immunodeficiency virus-infected patients with mild dyslipidemia.
Insulin Resistance
Assessment of Serum VASPIN Levels among Type 2 Diabetes Mellitus Patients with or without Acute Coronary Syndrome.
Insulin Resistance
Association between altered expression of adipogenic factor SREBP1 in lipoatrophic adipose tissue from HIV-1-infected patients and abnormal adipocyte differentiation and insulin resistance.
Insulin Resistance
Atazanavir/ritonavir-based combination antiretroviral therapy for treatment of HIV-1 infection in adults.
Insulin Resistance
Bezafibrate-induced improvement in glucose uptake and endothelial function in protease inhibitor-associated insulin resistance.
Insulin Resistance
Changes in Insulin Resistance After Initiation of Raltegravir or Protease Inhibitors With Tenofovir-Emtricitabine: AIDS Clinical Trials Group A5260s.
Insulin Resistance
Circulating levels and subcutaneous adipose tissue gene expression of pigment epithelium-derived factor in polycystic ovary syndrome and normal women: a case control study.
Insulin Resistance
Clinical aspects of endothelial dysfunction associated with human immunodeficiency virus infection and antiretroviral agents.
Insulin Resistance
Contribution of Adipose Tissue to the Chronic Immune Activation and Inflammation Associated With HIV Infection and Its Treatment.
Insulin Resistance
Danoprevir, an HCV NS3/4A protease inhibitor, improves insulin sensitivity in patients with genotype 1 chronic hepatitis C.
Insulin Resistance
Diabetes, insulin resistance and dyslipidaemia in lipodystrophic HIV-infected patients on highly active antiretroviral therapy (HAART).
Insulin Resistance
Downregulation of mitochondrial lon protease impairs mitochondrial function and causes hepatic insulin resistance in human liver SK-HEP-1 cells.
Insulin Resistance
Dyslipidaemia associated with antiretroviral therapy in HIV-infected patients.
Insulin Resistance
Effect of atazanavir and ritonavir on the differentiation and adipokine secretion of human subcutaneous and omental preadipocytes.
Insulin Resistance
Effect of metformin and rosiglitazone on lipid metabolism in HIV infected patients receiving protease inhibitor containing HAART.
Insulin Resistance
Effect of nelfinavir on insulin metabolism, proteasome activity and protein degradation in HepG2 cells.
Insulin Resistance
Effect of pregnancy and diabetes on myofibrillar protease activity in maternal and fetal muscles.
Insulin Resistance
Effect of rosiglitazone and metformin on insulin resistance in patients infected with human immunodeficiency virus receiving highly active antiretroviral therapy containing protease inhibitor: randomized prospective controlled clinical trial.
Insulin Resistance
Effects of boosted tipranavir and lopinavir on body composition, insulin sensitivity and adipocytokines in antiretroviral-naive adults.
Insulin Resistance
Effects of metformin on insulin resistance and central adiposity in patients receiving effective protease inhibitor therapy.
Insulin Resistance
Effects of metformin or gemfibrozil on the lipodystrophy of HIV-infected patients receiving protease inhibitors.
Insulin Resistance
Effects of troglitazone on insulin sensitivity in HIV-infected patients with protease inhibitor-associated diabetes mellitus.
Insulin Resistance
Elevated Resting and Postprandial Digestive Proteolytic Activity in Peripheral Blood of Individuals With Type-2 Diabetes Mellitus, With Uncontrolled Cleavage of Insulin Receptors.
Insulin Resistance
Endocrine and metabolic disorders associated with human immune deficiency virus infection.
Insulin Resistance
Endoplasmic reticulum stress in diabetes: New insights of clinical relevance.
Insulin Resistance
Evidence of human immunodeficiency virus-associated lipodystrophy syndrome in children treated with protease inhibitors.
Insulin Resistance
Fasting hyperinsulinemia in human immunodeficiency virus-infected men: relationship to body composition, gonadal function, and protease inhibitor use.
Insulin Resistance
Genetic variation in the vaspin gene affects circulating serum vaspin concentrations.
Insulin Resistance
Glycaemic consequences of HIV and highly active antiretroviral therapy: a pilot study and review of literature.
Insulin Resistance
H-risk dysmetabolism disorders associated with HAART-treated HIV disease, and reimbursement of lipid-lowering drugs, in a clinical and a socio-economic perspective.
Insulin Resistance
Hepatitis C virus infection is associated with insulin resistance among older adults with or at risk of HIV infection.
Insulin Resistance
HIV protease inhibitor substitution in patients with lipodystrophy: a randomized, controlled, open-label, multicentre study.
Insulin Resistance
HIV protease inhibitors and insulin resistance: lessons from in-vitro, rodent and healthy human volunteer models.
Insulin Resistance
HIV protease inhibitors induce metabolic dysfunction in part via increased JNK1/2 pro-inflammatory signaling in L6 cells.
Insulin Resistance
HIV-1 protease inhibitors induce an increase of triglyceride level in HIV-infected men without modification of insulin sensitivity: a longitudinal study.
Insulin Resistance
Human immunodeficiency virus protease inhibitors accumulate into cultured human adipocytes and alter expression of adipocytokines.
Insulin Resistance
Human obesity and thinness, hyperlipidemia, hyperglycemia, and insulin resistance associated with HIV1 protease inhibitors. Prevention by alternating several antiproteases in short sequences.
Insulin Resistance
Hyperlipidemia and insulin resistance are induced by protease inhibitors independent of changes in body composition in patients with HIV infection.
Insulin Resistance
Iatrogenic lipodystrophy in HIV patients - the need for very-low-fat diets.
Insulin Resistance
Identification of proteasome gene regulation in a rat model for HIV protease inhibitor-induced hyperlipidemia.
Insulin Resistance
Immunological blockade of adipocyte inflammation caused by increased matrix metalloproteinase-cleaved osteopontin in obesity.
Insulin Resistance
Improvement in insulin sensitivity and dyslipidemia in protease inhibitor-treated adult male patients after switch to atazanavir/ritonavir.
Insulin Resistance
Improvement of HAART-associated insulin resistance and dyslipidemia after replacement of protease inhibitors with abacavir.
Insulin Resistance
In vitro and in vivo prevention of HIV protease inhibitor-induced insulin resistance by a novel small molecule insulin receptor activator.
Insulin Resistance
Incidence of myocardial infarction in randomized clinical trials of protease inhibitor-based antiretroviral therapy: an analysis of four different protease inhibitors.
Insulin Resistance
Increased 24 h mean insulin-like growth factor binding protein-3 proteolytic activity in pubertal type 1 diabetic boys.
Insulin Resistance
Increased rates of lipolysis among human immunodeficiency virus-infected men receiving highly active antiretroviral therapy.
Insulin Resistance
Inhibition of lipolysis improves insulin sensitivity in protease inhibitor-treated HIV-infected men with fat redistribution.
Insulin Resistance
Inhibition of Serine Protease Activity Protects Against High Fat Diet-Induced Inflammation and Insulin Resistance.
Insulin Resistance
Insulin resistance complicating pregnancy in a human immunodeficiency virus-infected patient treated with protease inhibitors and corticosteroids.
Insulin Resistance
Insulin resistance in HIV infection: drugs, host responses, or restoration to health?
Insulin Resistance
Insulin resistance in the HIV-infected population: the potential role of mitochondrial dysfunction.
Insulin Resistance
Insulin sensitivity and beta-cell function in protease inhibitor-treated and -naive human immunodeficiency virus-infected children.
Insulin Resistance
Intramyocellular lipid accumulation and reduced whole body lipid oxidation in HIV lipodystrophy.
Insulin Resistance
LDL-receptors expression in HIV-infected patients: relations to antiretroviral therapy, hormonal status, and presence of lipodystrophy.
Insulin Resistance
Lipid profile improvement in virologically suppressed HIV-1-infected patients switched to dolutegravir/abacavir/lamivudine: data from the SCOLTA project.
Insulin Resistance
Lipodystrophy defined by a clinical score in HIV-infected men on highly active antiretroviral therapy: correlation between dyslipidaemia and steroid hormone alterations.
Insulin Resistance
Liver Fibrosis during Antiretroviral Treatment in HIV-Infected Individuals. Truth or Tale?
Insulin Resistance
Liver-Specific Overexpression of Prostasin Attenuates High-Fat Diet-Induced Metabolic Dysregulation in Mice.
Insulin Resistance
Long-term effects of HIV-1 protease inhibitors on insulin secretion and insulin signaling in INS-1 beta cells.
Insulin Resistance
Lopinavir inhibits insulin signaling by promoting protein tyrosine phosphatase 1B expression.
Insulin Resistance
Loss of mitochondrial protease ClpP protects mice from diet-induced obesity and insulin resistance.
Insulin Resistance
Macrophage ubiquitin-specific protease 2 modifies insulin sensitivity in obese mice.
Insulin Resistance
Markedly diminished lipolysis and partial restoration of glucose metabolism, without changes in fat distribution after extended discontinuation of protease inhibitors in severe lipodystrophic human immunodeficient virus-1-infected patients.
Insulin Resistance
Mechanisms for the deterioration in glucose tolerance associated with HIV protease inhibitor regimens.
Insulin Resistance
Metabolic and neurologic consequences of chronic lopinavir/ritonavir administration to C57BL/6 mice.
Insulin Resistance
Metabolic disorders among HIV-infected patients treated with protease inhibitors: a review.
Insulin Resistance
Metabolic syndrome and cardiovascular disease in patients with human immunodeficiency virus.
Insulin Resistance
Metformin in an HIV-infected patient with protease inhibitor-induced diabetic ketoacidosis.
Insulin Resistance
Morphologic and metabolic abnormalities in vertically HIV-infected children and youth.
Insulin Resistance
Overcoming obstacles to the success of protease inhibitors in highly active antiretroviral therapy regimens.
Insulin Resistance
Overweight HIV patients with abdominal fat distribution treated with protease inhibitors are at high risk for abnormalities in glucose metabolism - a reason for glycemic control.
Insulin Resistance
Pathophysiological Implication of Fetuin-A Glycoprotein in the Development of Metabolic Disorders: A Concise Review.
Insulin Resistance
Pigment epithelium-derived factor contributes to insulin resistance in obesity.
Insulin Resistance
Polyalthia Clerodane Diterpene Potentiates Hypoglycemia via Inhibition of Dipeptidyl Peptidase 4.
Insulin Resistance
Prospective evaluation of the effect of initiating indinavir-based therapy on insulin sensitivity and B-cell function in HIV-infected patients.
Insulin Resistance
Protease inhibitor effects on triglyceride synthesis and adipokine secretion in human omental and subcutaneous adipose tissue.
Insulin Resistance
Protease inhibitor-based antiretroviral therapy and glucose tolerance in pregnancy: AIDS Clinical Trials Group A5084.
Insulin Resistance
Quantification of insulin-mediated glucose disposal in HIV-infected individuals: comparison of patients treated and untreated with protease inhibitors.
Insulin Resistance
Rationale and clinical utility of the darunavir-cobicistat combination in the treatment of HIV/AIDS.
Insulin Resistance
Regulation of visceral adipose tissue-derived serine protease inhibitor by nutritional status, metformin, gender and pituitary factors in rat white adipose tissue.
Insulin Resistance
Relative effects of insulin resistance and protease inhibitor treatment on lipid and lipoprotein metabolism in HIV-infected patients.
Insulin Resistance
Respiratory failure associated with the lipodystrophy syndrome in an HIV-positive patient with compromised lung function.
Insulin Resistance
Risk of premature atherosclerosis and ischemic heart disease associated with HIV infection and antiretroviral therapy.
Insulin Resistance
Risks of cardiovascular disease in patients receiving antiretroviral therapy for HIV infection: implications for treatment.
Insulin Resistance
Role of vaspin in porcine ovary: effect on signaling pathways and steroid synthesis via GRP78 receptor and protein kinase A.
Insulin Resistance
Sarcopenia in Persons Living with HIV under Antiretroviral Therapy: Literature Review.
Insulin Resistance
Serum levels of fetuin-A in patients with coronary artery disease. Corellation with SPET myocardium scintigraphy.
Insulin Resistance
Serum levels of pigment epithelium-derived factor (PEDF) are positively associated with acanthosis nigricans in obese adolescents.
Insulin Resistance
Single-dose lopinavir-ritonavir acutely inhibits insulin-mediated glucose disposal in healthy volunteers.
Insulin Resistance
Stimulation of peroxisome proliferator-activated receptors alpha and gamma blocks HIV-1 replication and TNFalpha production in acutely infected primary blood cells, chronically infected U1 cells, and alveolar macrophages from HIV-infected subjects.
Insulin Resistance
Syndrome of lipodystrophy, hyperlipidemia, insulin resistance, and diabetes in treated patients with human immunodeficiency virus infection.
Insulin Resistance
The HIV protease inhibitor indinavir impairs sterol regulatory element-binding protein-1 intranuclear localization, inhibits preadipocyte differentiation, and induces insulin resistance.
Insulin Resistance
The HIV-1 protease inhibitor indinavir impairs insulin signalling in HepG2 hepatoma cells.
Insulin Resistance
The mechanism of insulin resistance caused by HIV protease inhibitor therapy.
Insulin Resistance
The protease inhibitor combination lopinavir/ritonavir does not decrease insulin secretion in healthy, HIV-seronegative volunteers.
Insulin Resistance
The role of protease inhibitors in the pathogenesis of HIV-associated insulin resistance: cellular mechanisms and clinical implications.
Insulin Resistance
The serine protease prostasin regulates hepatic insulin sensitivity by modulating TLR4 signalling.
Insulin Resistance
Thiazolidinediones could improve endothelial dysfunction and risk of premature coronary heart disease in HIV-infected patients.
Insulin Resistance
Treatment with protease inhibitors associated with peripheral insulin resistance and impaired oral glucose tolerance in HIV-1-infected patients.
Insulin Resistance
Vaspin alleviates myocardial ischaemia/reperfusion injury via activating autophagic flux and restoring lysosomal function.
Insulin Resistance
Vaspin is related to gender, puberty and deteriorating insulin sensitivity in children.
Insulin Resistance
Visceral adiposity, C-peptide levels, and low lipase activities predict HIV-dyslipidemia.
Insulin Resistance
[Abnormal body fat distribution and type of antiretroviral therapy as predictors of cardiovascular disease risk in HIV-infected patients]
Insulin Resistance
[Acute myocardial infarct in HIV-positive patients in treatment with protease inhibitors]
Insulin Resistance
[Correlation between vaspin concentration and insulin sensitivity in the visceral adipose tissue of young obese rats].
Insulin Resistance
[Diabetic ketoacidosis in an HIV-infected patient undergoing antiretroviral therapy]
Insulin Resistance
[Overview on hypoglycemic active constituents of traditional Chinese medicine based on insulin receptor signaling pathway].
Insulinoma
A neurosecretory granule Lys-Arg Ca(2+)-dependent endopeptidase putatively involved in prooxytocin and provasopressin processing.
Insulinoma
Isolation of two complementary deoxyribonucleic acid clones from a rat insulinoma cell line based on similarities to Kex2 and furin sequences and the specific localization of each transcript to endocrine and neuroendocrine tissues in rats.
Intellectual Disability
A mental retardation gene, motopsin/prss12, modulates cell morphology by interaction with seizure-related gene 6.
Intellectual Disability
A mutation in a novel ATP-dependent Lon protease gene in a kindred with mild mental retardation.
Intellectual Disability
Activity-induced synaptic capture and exocytosis of the neuronal serine protease neurotrypsin.
Intellectual Disability
Coincident pre- and postsynaptic activation induces dendritic filopodia via neurotrypsin-dependent agrin cleavage.
Intellectual Disability
Enzymatic properties and localization of motopsin (PRSS12), a protease whose absence causes mental retardation.
Intellectual Disability
Specific cleavage of agrin by neurotrypsin, a synaptic protease linked to mental retardation.
Intellectual Disability
The deubiquitinase USP6 affects memory and synaptic plasticity through modulating NMDA receptor stability.
Intellectual Disability
The mental retardation-related protease, motopsin (prss12), binds to the BRICHOS domain of the integral membrane protein 2a.
Intellectual Disability
Truncating neurotrypsin mutation in autosomal recessive nonsyndromic mental retardation.
Intervertebral Disc Degeneration
Chondroadherin fragmentation mediated by the protease HTRA1 distinguishes human intervertebral disc degeneration from normal aging.
Intervertebral Disc Degeneration
Correlation between the Expression of High Temperature Requirement Serine Protease A1 in Nucleus Pulposus Tissue and the Degree of Intervertebral Disc Degeneration.
Intervertebral Disc Degeneration
Lycorine Suppresses Endplate-Chondrocyte Degeneration and Prevents Intervertebral Disc Degeneration by Inhibiting NF-?B Signalling Pathway.
Intervertebral Disc Degeneration
Toll-like Receptor Activation Induces Degeneration of Human Intervertebral Discs.
Intervertebral Disc Degeneration
[RESEARCH PROGRESS OF microRNA IN INTERVERTEBRAL DISC DEGENERATION].
Intestinal Failure
Matriptase drives early-onset intestinal failure in a mouse model of congenital tufting enteropathy.
Intestinal Volvulus
Characterization of a novel filarial serine protease inhibitor, Ov-SPI-1, from Onchocerca volvulus, with potential multifunctional roles during development of the parasite.
Intestinal Volvulus
Guatemalan human onchocerciasis. I. Systematic analysis of patient populations, nodular antigens, and specific isotypic reactions.
Intestinal Volvulus
Identification of a novel family of non-lysosomal aspartic proteases in nematodes.
Intestinal Volvulus
Wolbachia endosymbionts of Onchocerca volvulus express a putative periplasmic HtrA-type serine protease.
Intra-Abdominal Hypertension
Japanese guidelines for the management of acute pancreatitis: Japanese Guidelines 2015.
Intracranial Hemorrhages
Activated protein C inhibits tissue plasminogen activator-induced brain hemorrhage.
Intracranial Hemorrhages
Intracranial hemorrhage and liver-associated deaths associated with tipranavir/ritonavir: review of cases from the FDA's Adverse Event Reporting System.
Intracranial Thrombosis
Protease nexin-2/amyloid beta-protein precursor limits cerebral thrombosis.
Invasive Pulmonary Aspergillosis
Histopathology of experimental invasive pulmonary aspergillosis in rats: pathological comparison of pulmonary lesions induced by specific virulent factor deficient mutants.
Invasive Pulmonary Aspergillosis
Induction of mucin and MUC5AC expression by the protease activity of Aspergillus fumigatus in airway epithelial cells.
Iritis
Iritis and hypotony after treatment with intravenous cidofovir for cytomegalovirus retinitis.
Iron Deficiencies
Matriptase-2 mutations in iron-refractory iron deficiency anemia patients provide new insights into protease activation mechanisms.
Iron Deficiencies
The Association of TMPRSS6 Gene Polymorphism and Iron Intake with Iron Status among Under-Two-Year-Old Children in Lombok, Indonesia.
Iron Deficiencies
The decreased growth performance and impaired immune function and structural integrity by dietary iron deficiency or excess are associated with TOR, NF-?B, p38MAPK, Nrf2 and MLCK signaling in head kidney, spleen and skin of grass carp (Ctenopharyngodon idella).
Iron Deficiencies
The impaired immune function and structural integrity by dietary iron deficiency or excess in gill of fish after infection with Flavobacterium columnare: Regulation of NF-?B, TOR, JNK, p38MAPK, Nrf2 and MLCK signalling.
Iron Deficiencies
The serine protease matriptase-2 (TMPRSS6) inhibits hepcidin activation by cleaving membrane hemojuvelin.
Iron Overload
Applying microarray-based technique to study and analyze silkworm (Bombyx mori) transcriptomic response to long-term high iron diet.
Irritable Bowel Syndrome
Altered protease signalling in the gut: a novel pathophysiological factor in irritable bowel syndrome.
Irritable Bowel Syndrome
Characterisation of faecal protease activity in irritable bowel syndrome with diarrhoea: origin and effect of gut transit.
Irritable Bowel Syndrome
Growth, phenotype, and function of human intestinal mast cells are tightly regulated by transforming growth factor beta1.
Irritable Bowel Syndrome
Increased faecal serine protease activity in diarrhoeic IBS patients: a colonic lumenal factor impairing colonic permeability and sensitivity.
Irritable Bowel Syndrome
Newly developed serine protease inhibitors decrease visceral hypersensitivity in a post-inflammatory rat model for irritable bowel syndrome.
Irritable Bowel Syndrome
Protease activated receptor 4 status of mast cells in post infectious irritable bowel syndrome.
Irritable Bowel Syndrome
Protease Activated Receptor-2 Induces Immune Activation and Visceral Hypersensitivity in Post-infectious Irritable Bowel Syndrome Mice.
Irritable Bowel Syndrome
Protease signaling through protease activated receptor 1 mediate nerve activation by mucosal supernatants from irritable bowel syndrome but not from ulcerative colitis patients.
Irritable Bowel Syndrome
Role for protease activity in visceral pain in irritable bowel syndrome.
Irritable Bowel Syndrome
Sensitization of Peripheral Sensory Nerves by Mediators From Colonic Biopsies of Diarrhea-Predominant Irritable Bowel Syndrome Patients: A Role for PAR2.
Ischemic Attack, Transient
Dipeptidyl peptidase IV, aminopeptidase N and DPIV/APN-like proteases in cerebral ischemia.
Ischemic Attack, Transient
Induction of caspase-3-like protease may mediate delayed neuronal death in the hippocampus after transient cerebral ischemia.
Ischemic Stroke
Activated protein C analog promotes neurogenesis and improves neurological outcome after focal ischemic stroke in mice via protease activated receptor 1.
Ischemic Stroke
Activated Protein C Attenuates Experimental Autoimmune Encephalomyelitis Progression by Enhancing Vascular Integrity and Suppressing Microglial Activation.
Ischemic Stroke
Contribution of extracellular proteolysis and microglia to intracerebral hemorrhage.
Ischemic Stroke
Effect of the Pleiotropic Drug CNB-001 on Tissue Plasminogen Activator (tPA) Protease Activity in vitro: Support for Combination Therapy to Treat Acute Ischemic Stroke.
Ischemic Stroke
Effects of exogenous recombinant APC in mouse models of ischemia reperfusion injury and of atherosclerosis.
Ischemic Stroke
Epigenetic Regulation of Tissue-Type Plasminogen Activator in Human Brain Tissue and Brain-Derived Cells.
Ischemic Stroke
Expression of plasminogen activator inhibitor-1 and protease nexin-1 in human astrocytes: Response to injury-related factors.
Ischemic Stroke
HMGB-1 promotes fibrinolysis and reduces neurotoxicity mediated by tissue plasminogen activator.
Ischemic Stroke
In vivo ultrasound-activated delivery of recombinant tissue plasminogen activator from the cavity of sub-micrometric capsules.
Ischemic Stroke
Increased serum levels of endogenous protectant secretory leukocyte protease inhibitor in acute ischemic stroke patients.
Ischemic Stroke
Infarct reduction in rats following intraventricular administration of either tissue plasminogen activator (tPA) or its non-protease mutant S478A-tPA.
Ischemic Stroke
Nafamostat mesilate attenuates neuronal damage in a rat model of transient focal cerebral ischemia through thrombin inhibition.
Ischemic Stroke
NF-?B-dependent and -independent pathways in the protective effects of activated protein C in hippocampal and cortical neurons at excitotoxicity.
Ischemic Stroke
Pathophysiologic mechanisms of acute ischemic stroke: An overview with emphasis on therapeutic significance beyond thrombolysis.
Ischemic Stroke
Physiological cerebrovascular remodeling in response to chronic mild hypoxia: A role for activated protein C.
Ischemic Stroke
Plasma FVII-activating protease (FSAP) antigen and activity levels are increased in ischemic stroke.
Ischemic Stroke
Proteomic Protease Substrate Profiling of tPA Treatment in Acute Ischemic Stroke Patients: A Step Toward Individualizing Thrombolytic Therapy at the Bedside.
Ischemic Stroke
Recent Developments regarding Human Immunodeficiency Virus Infection and Stroke.
Ischemic Stroke
Structural basis of specific inhibition of tissue-type plasminogen activator by plasminogen activators inhibitor-1.
Ischemic Stroke
Structural requirements for activation of latent platelet-derived growth factor CC by tissue plasminogen activator.
Ischemic Stroke
Suppression of ischaemia-induced injuries in rat brain by protease-activated receptor-1 (PAR-1) activating peptide.
Ischemic Stroke
The role of endogenous tissue-type plasminogen activator in neuronal survival after ischemic stroke: friend or foe?
Ischemic Stroke
Tissue plasminogen activator (tPA) and matrix metalloproteinases in the pathogenesis of stroke: therapeutic strategies.
Ischemic Stroke
Tissue plasminogen activator does not alter development of acquired epilepsy.
Ischemic Stroke
tPA Deficiency in Mice Leads to Rearrangement in the Cerebrovascular Tree and Cerebroventricular Malformations.
Ischemic Stroke
Up-regulation of secretory leukocyte protease inhibitor (SLPI) in the brain after ischemic stroke: adenoviral expression of SLPI protects brain from ischemic injury.
Ischemic Stroke
Xenon is an inhibitor of tissue-plasminogen activator: adverse and beneficial effects in a rat model of thromboembolic stroke.
Joint Diseases
Identification of a Novel HtrA1-susceptible cleavage site in human aggrecan: evidence for the involvement of HtrA1 in aggrecan proteolysis in vivo.
Joint Diseases
Secretory leukocyte protease inhibitor suppresses the inflammation and joint damage of bacterial cell wall-induced arthritis.
Joint Diseases
[Protease inhibitors of the synovial fluid in the pathogenesis and diagnosis of joint diseases]
Keloid
Adenoviral overexpression and small interfering RNA suppression demonstrate that plasminogen activator inhibitor-1 produces elevated collagen accumulation in normal and keloid fibroblasts.
Keratitis
A Pseudomonas aeruginosa strain isolated from a contact lens-induced acute red eye (CLARE) is protease-deficient.
Keratitis
Acanthamoeba: a review of its potential to cause keratitis, current lens care solution disinfection standards and methodologies, and strategies to reduce patient risk.
Keratitis
Characterization of rabbit corneal damage produced by Serratia keratitis and by a serratia protease.
Keratitis
Comparison of virulence factors in Pseudomonas aeruginosa strains isolated from contact lens- and non-contact lens-related keratitis.
Keratitis
Degradation of uniquely glycosylated secretory immunoglobulin a in tears from patients with Pseudomonas aeruginosa keratitis.
Keratitis
Determination of quorum-sensing signal molecules and virulence factors of Pseudomonas aeruginosa isolates from contact lens-induced microbial keratitis.
Keratitis
Genetic features of Pseudomonas aeruginosa isolates associated with eye infections referred to Farabi Hospital, Tehran, Iran.
Keratitis
Immunization against experimental Pseudomonas aeruginosa and Serratia marcescens keratitis. Vaccination with lipopolysaccharide endotoxins and proteases.
Keratitis
Mechanism of Pseudomonas aeruginosa Small Protease (PASP), a Corneal Virulence Factor.
Keratitis
Pseudomonas aeruginosa MucD protease mediates keratitis by inhibiting neutrophil recruitment and promoting bacterial survival.
Keratitis
Pseudomonas keratitis. The role of an uncharacterized exoprotein, protease IV, in corneal virulence.
Keratitis
Purification and characterization of a 33 kDa serine protease from Acanthamoeba lugdunensis KA/E2 isolated from a Korean keratitis patient.
Keratitis
Relationship between proteases and descemetocele formation in experimental Pseudomonas keratitis.
Keratitis
Relationship of Virulence Factors and Clinical Features in Keratitis Caused by Pseudomonas aeruginosa.
Keratitis
Role of contact lens wear, bacterial flora, and mannose-induced pathogenic protease in the pathogenesis of amoebic keratitis.
Keratitis
Secretory Leukoprotease Inhibitor: A Native Antimicrobial Protein in the Innate Immune Response in a Rat Model of S. aureus Keratitis.
Keratitis
Strategies for the prevention of contact lens-related Acanthamoeba keratitis: a review.
Keratitis
The serratial 56K protease as a major pathogenic factor in serratial keratitis. Clinical and experimental study.
Keratitis
Type III Secretion System-Associated Toxins, Proteases, Serotypes, and Antibiotic Resistance of Pseudomonas aeruginosa Isolates Associated with Keratitis.
Keratoconjunctivitis
Effects of Ocimum gratissimum L essential oil at subinhibitory concentrations on virulent and multidrug-resistant Shigella strains from Lagos, Nigeria.
Keratoconjunctivitis Sicca
Association of HLA-DR4, protease inhibitor phenotypes and keratoconjunctivitis sicca with pulmonary abnormalities in rheumatoid arthritis.
Keratoconus
Cathepsin G, acid phosphatase, and alpha 1-proteinase inhibitor messenger RNA levels in keratoconus corneas.
Keratoconus
Effects of eye rubbing on the levels of protease, protease activity and cytokines in tears: relevance in keratoconus.
Keratoconus
Expression of degradative enzymes and protease inhibitors in corneas with keratoconus.
Keratoconus
Levels of alpha1-proteinase inhibitor and alpha2-macroglobulin in the tear film of patients with keratoconus.
Keratoconus
Normal expression levels of cathepsins, protease inhibitors, and Sp1 in conjunctival tissues from patients with keratoconus.
Keratoderma, Palmoplantar
Human elastase 1: evidence for expression in the skin and the identification of a frequent frameshift polymorphism.
Keratoderma, Palmoplantar
Mutations in SERPINB7, encoding a member of the serine protease inhibitor superfamily, cause Nagashima-type palmoplantar keratosis.
Keratoderma, Palmoplantar
Nagashima-type palmoplantar keratosis: a common Asian type caused by SERPINB7 protease inhibitor deficiency.
Keratosis
Acral peeling in Nagashima type palmo-plantar keratosis patients reveals the role of serine protease inhibitor B 7 in keratinocyte adhesion.
Keratosis, Actinic
The serine protease inhibitor of Kazal-type 9 (SPINK9) is expressed in lichen simplex chronicus, actinic keratosis and squamous cell carcinoma.
Ketosis
Diabetes responsive to intravenous but not subcutaneous insulin: effectiveness of aprotinin.
Kidney Calculi
Effects of inter-alpha-inhibitor and several of its derivatives on calcium oxalate crystallization in vitro.
Kidney Cortex Necrosis
Antiserum against tumor necrosis factor-alpha and a protease inhibitor reduce immune glomerular injury.
Kidney Diseases
A serine protease inhibitor attenuates aldosterone-induced kidney injuries via the suppression of plasmin activity.
Kidney Diseases
NMR and MS urinary metabolic phenotyping in kidney diseases is fit-for-purpose in the presence of a protease inhibitor.
Kidney Diseases
The Multifaceted Role of the Lysosomal Protease Cathepsins in Kidney Disease.
Kidney Failure, Chronic
Alteration in insulin-like growth factor-binding proteins (IGFBPs) and IGFBP-3 protease activity in serum and urine from acute and chronic renal failure.
Kidney Failure, Chronic
Effect of a protease inhibitor on in vitro stability of intact parathyroid hormone.
Kidney Failure, Chronic
Effect of a serine protease inhibitor on the progression of chronic renal failure.
Kidney Failure, Chronic
Epidermal Proteinase-Activated Receptor-2 Expression is Increased in End-Stage Renal Disease Patients with Pruritus: A Pilot Study.
Kidney Failure, Chronic
Evaluation of the proteolytic activity of factor D accumulated as an active serine protease in patients with chronic renal failure.
Kidney Failure, Chronic
Fibrinolytic and protease inhibitory systems in spinal cord injured patients with end-stage renal disease.
Kidney Failure, Chronic
HIV-2 Infection, End-Stage Renal Disease and Protease Inhibitor Intolerance: Which Salvage Regimen?
Kidney Failure, Chronic
Human chronic kidney allograft rejection is accompanied by increased intraglomerular cathepsin B and L activity.
Kidney Failure, Chronic
Increased plasma glycosidase and protease activity in uraemia: possible role in the aetiology of the anaemia of chronic renal failure.
Kidney Failure, Chronic
Insulin-like growth factor binding protein-3 protease activity in the urine of children with chronic renal failure.
Kidney Failure, Chronic
Overhydration Measured by Bioimpedance Spectroscopy and Urinary Serine Protease Activity Are Risk Factors for Progression of Chronic Kidney Disease.
Kidney Failure, Chronic
Proteomic and metabolomic characterization of streptozotocin-induced diabetic nephropathy in TIMP3-deficient mice.
Kidney Failure, Chronic
Utility of protease-digested human peripheral blood lymphocytes for the detection of lymphocyte-reactive alloantibodies by indirect immunofluorescence.
Kidney Neoplasms
Combination of suberoylanilide hydroxamic acid and ritonavir is effective against renal cancer cells.
Kidney Neoplasms
Downregulation of ubiquitin-specific protease 2 possesses prognostic and diagnostic value and promotes the clear cell renal cell carcinoma progression.
Kidney Neoplasms
Inhibition of aminopeptidase N (AP-N) and urokinase-type plasminogen activator (uPA) by zinc suppresses the invasion activity in human urological cancer cells.
Lactose Intolerance
Molecular Characterization and In Vitro Analyses of a Sporogenous Bacterium with Potential Probiotic Properties.
Laminopathies
HIV protease inhibitors inhibit FACE1/ZMPSTE24: a mechanism for acquired lipodystrophy in patients on highly active antiretroviral therapy?
Leg Ulcer
A 'test and treat' strategy for elevated wound protease activity for healing in venous leg ulcers.
Leg Ulcer
Cytokine and protease levels in healing and non-healing chronic venous leg ulcers.
Leg Ulcer
Effect of oxidised regenerated cellulose/collagen matrix on proteases in wound exudate of patients with chronic venous ulceration.
Leg Ulcer
Embedding National Institute for Health and Care Excellence guidance into a leg ulcer pathway.
Leg Ulcer
Quantification of secretory leucocyte protease inhibitor in exudates from leg ulcers of patients with diabetes.
Leg Ulcer
Wound fluid from venous leg ulcers degrades plasminogen and reduces plasmin generation by keratinocytes.
Legionnaires' Disease
Demonstration of the intracellular production of tissue-destructive protease by Legionella pneumophila multiplying within guinea-pig and human alveolar macrophages.
Legionnaires' Disease
Effect of Legionella pneumophila cytotoxic protease on human neutrophil and monocyte function.
Legionnaires' Disease
Effects of an isogenic Zn-metalloprotease-deficient mutant of Legionella pneumophila in a guinea-pig pneumonia model.
Legionnaires' Disease
Immunocytochemical demonstration of the association between Legionella pneumophila, its tissue-destructive protease, and pulmonary lesions in experimental legionnaires' disease.
Legionnaires' Disease
In vitro secretion kinetics of proteins from Legionella pneumophila in comparison to proteins from non-pneumophila species.
Legionnaires' Disease
In vivo production of a tissue-destructive protease by Legionella pneumophila in the lungs of experimentally infected guinea-pigs.
Legionnaires' Disease
Inhibition of human natural killer cell activity by Legionella pneumophila protease.
Legionnaires' Disease
Inhibition of oxidative burst and chemotaxis in human phagocytes by Legionella pneumophila zinc metalloprotease.
Legionnaires' Disease
Inhibition of polymorphonuclear leukocyte function by Legionella pneumophila exoproducts.
Legionnaires' Disease
Legionella pneumophila protease inactivates interleukin-2 and cleaves CD4 on human T cells.
Legionnaires' Disease
Separation of Legionella pneumophila proteases and purification of a protease which produces lesions like those of Legionnaires' disease in guinea pig lung.
Leigh Disease
Defective mitochondrial protease LonP1 can cause classical mitochondrial disease.
Leiomyoma
Accumulation of retinoid X receptor-alpha in uterine leiomyomas is associated with a delayed ligand-dependent proteasome-mediated degradation and an alteration of its transcriptional activity.
Leiomyoma
Altered post-translational modification of redox factor 1 protein in human uterine smooth muscle tumors.
Leiomyoma
Relaxin increases elastase activity and protease inhibitors in smooth muscle cells from the myometrium compared with cells from leiomyomas.
Leiomyoma
The two native estrogen receptor forms of 8S and 4S present in cytosol from human uterine tissues display opposite reactivities with the antiestrogen tamoxifen aziridine and the estrogen responsive element.
Leishmaniasis
Enhancement of experimental cutaneous leishmaniasis by Leishmania molecules is dependent on interleukin-4, serine protease/esterase activity, and parasite and host genetic backgrounds.
Leishmaniasis
In vitro anti-leishmanial efficacy of potato tuber extract (PTEx): leishmanial serine protease(s) as putative target.
Leishmaniasis
Natural products from Garcinia brasiliensis as Leishmania protease inhibitors.
Leishmaniasis
Novel compounds to combat trypanosomatid infections: a medicinal chemical perspective.
Leishmaniasis
Protease inhibitors as prophylaxis against leishmaniasis: new hope from the major surface protease gp63.
Leishmaniasis
The major surface glycoprotein (gp63) from Leishmania major and Leishmania donovani cleaves CD4 molecules on human T cells.
Leishmaniasis, Visceral
115kDa serine protease confers sustained protection to visceral leishmaniasis caused by Leishmania donovani via IFN-? induced down-regulation of TNF-? mediated MMP-9 activity.
Leishmaniasis, Visceral
Antiproteolytic and leishmanicidal activity of Coccinia grandis (L.) Voigt leaf extract against Leishmania donovani promastigotes.
Leishmaniasis, Visceral
Curative efficacy of purified serine protease inhibitor PTF3 from potato tuber in experimental visceral leishmaniasis.
Leishmaniasis, Visceral
Efficacy of protease inhibitor from marine Streptomyces sp. VITBVK2 against Leishmania donovani - An in vitro study.
Leishmaniasis, Visceral
HIV-1 protease inhibitors for treatment of visceral leishmaniasis in HIV-co-infected individuals.
Leishmaniasis, Visceral
Identification, purification, and characterization of a secretory serine protease in an Indian strain of Leishmania donovani.
Leishmaniasis, Visceral
Leishmania donovani serine protease encapsulated in liposome elicits protective immunity in experimental visceral leishmaniasis.
Leishmaniasis, Visceral
Protective inflammatory response against visceral leishmaniasis with potato tuber extract: A new approach of successful therapy.
Leishmaniasis, Visceral
Relapsing visceral leishmaniasis in HIV-infected patients undergoing successful protease inhibitor therapy.
Leishmaniasis, Visceral
Serine protease inhibitors rich Coccinia grandis (L.) Voigt leaf extract induces protective immune responses in murine visceral leishmaniasis.
Leishmaniasis, Visceral
Signaling events leading to the curative effect of cystatin on experimental visceral leishmaniasis: involvement of ERK1/2, NF-kappaB and JAK/STAT pathways.
Leishmaniasis, Visceral
The role of calpain and calpastatin in the catabolism of erythrocyte-membrane proteins during anaemia in hamsters (Mesocricetus auretus) infected with Leishmania donovani.
Lens Subluxation
Crystalline lens dislocation secondary to bacterial endogenous endophthalmitis.
Leprosy, Lepromatous
Protease inhibitors activity in lepromatous leprosy and lepra reaction.
Leukemia
28-kDa mammalian heat shock protein, a novel substrate of a growth regulatory protease involved in differentiation of human leukemia cells.
Leukemia
A chymotrypsin-type serine protease in rat basophilic leukemia cells: evidence for its immunologic identity with atypical mast cell protease.
Leukemia
A multivalent DNA aptamer specific for the B-cell receptor on human lymphoma and leukemia.
Leukemia
A novel acidic serine protease, ASPNJ inhibits proliferation, induces apoptosis and enhances chemo-susceptibility of acute promyelocytic leukemia cell.
Leukemia
A novel ubiquitin-specific protease, UBP43, cloned from leukemia fusion protein AML1-ETO-expressing mice, functions in hematopoietic cell differentiation.
Leukemia
A protease-resistant PML-RAR{alpha} has increased leukemogenic potential in a murine model of acute promyelocytic leukemia.
Leukemia
Activation of actin-cleavable interleukin 1beta-converting enzyme (ICE) family protease CPP-32 during chemotherapeutic agent-induced apoptosis in ovarian carcinoma cells.
Leukemia
Antiretroviral activities of protease inhibitors against murine leukemia virus and simian immunodeficiency virus in tissue culture.
Leukemia
Avian oncornaviruses contain a virus coded protease (p15) which processes its own gag protein precursor and the 110 Kd polypeptide of MC29.
Leukemia
Avian sarcoma leukemia virus protease linked to the adjacent Gag polyprotein is enzymatically active.
Leukemia
Blockade of the Ubiquitin Protease UBP43 Destabilizes the Transcription Factor PML/RAR{alpha} and Inhibits Growth of Acute Promyelocytic Leukemia.
Leukemia
Camptothecin-induced apoptosis in p53-null human leukemia HL60 cells and their isolated nuclei: effects of the protease inhibitors Z-VAD-fmk and dichloroisocoumarin suggest an involvement of both caspases and serine proteases.
Leukemia
Can application of serine protease inhibitors TPCK and TLCK provide evidence for possible involvement of serine protease Omi/HtrA2 in imatinib mesylate-induced cell death of BCR-ABL-positive human leukemia cells?
Leukemia
Cathepsin G Is Expressed by Acute Lymphoblastic Leukemia and Is a Potential Immunotherapeutic Target.
Leukemia
Characterization of a virus-specific proteolytic activity processing the gag precursor of the simian sarcoma-associated virus.
Leukemia
Characterization of glucocorticoid receptors and glucocorticoid receptor mRNA in human leukemia cells: stabilization of the receptor by diisopropylfluorophosphate.
Leukemia
Characterization of the murine leukemia virus protease and its comparison with the human immunodeficiency virus type 1 protease.
Leukemia
Commentary on The Deubiquitinylation and localization of PTEN are regulated by a HAUSP-PML network Song MS, Salmena L, Carracedo A, Egia A, Lo-Coco F, Teruya-Feldstein J, Pandolfi PP, Cancer Genetics Program, Beth Israel Deaconess Cancer Center and Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA.
Leukemia
Comparative analysis of five highly conserved target sites within the HIV-1 RNA for their susceptibility to hammerhead ribozyme-mediated cleavage in vitro and in vivo.
Leukemia
Complete sequence of human T cell leukemia virus type 1 in ATLL patients from Northeast Iran, Mashhad revealed a prematurely terminated protease and an elongated pX open reading frame III.
Leukemia
Concentrations of insulin-like growth factor (IGF)-binding protein-3 (IGFBP-3), IGF, and IGFBP-3 protease activity in cerebrospinal fluid of children with leukemia, central nervous system tumor, or meningitis.
Leukemia
Crystal structure of XMRV protease differs from the structures of other retropepsins.
Leukemia
Cytoplasmic tail of Moloney murine leukemia virus envelope protein influences the conformation of the extracellular domain: implications for mechanism of action of the R Peptide.
Leukemia
Differential regulation of sentrinized proteins by a novel sentrin-specific protease.
Leukemia
DNA fragmentation induced by protease activation in p53-null human leukemia HL60 cells undergoing apoptosis following treatment with the topoisomerase I inhibitor camptothecin: cell-free system studies.
Leukemia
Down-regulation of a serine protease, myeloblastin, causes growth arrest and differentiation of promyelocytic leukemia cells.
Leukemia
Dysregulation of the cyclin-dependent kinase inhibitor p21WAF1/CIP1/MDA6 increases the susceptibility of human leukemia cells (U937) to 1-beta-D-arabinofuranosylcytosine-mediated mitochondrial dysfunction and apoptosis.
Leukemia
Expression of active human immunodeficiency virus type 1 protease by noninfectious chimeric virus particles.
Leukemia
Expression of the murine leukemia virus protease in fusion with maltose-binding protein in Escherichia coli.
Leukemia
Extracellular protease trypsin activates amiloride-insensitive sodium channels in human leukemia cells.
Leukemia
Function of the cytoplasmic domain of a retroviral transmembrane protein: p15E-p2E cleavage activates the membrane fusion capability of the murine leukemia virus Env protein.
Leukemia
Further characterization of the Friend murine leukemia virus reverse transcriptase-RNase H complex.
Leukemia
Genetic locus, primary structure, and chemical synthesis of human immunodeficiency virus protease.
Leukemia
Growth inhibition of U937 leukemia cells by aqueous extract of Cordyceps militaris through induction of apoptosis.
Leukemia
Human THP-1 monocytic leukemic cells induced to undergo monocytic differentiation by bryostatin 1 are refractory to proteasome inhibitor-induced apoptosis.
Leukemia
Hypoxia-induced USP22-BMI1 axis promotes the stemness and malignancy of glioma stem cells via regulation of HIF-1?.
Leukemia
Identification and cloning of a novel isoform of mouse secretory leukocyte protease inhibitor, mSLPI-beta, overexpressed in murine leukemias and a highly liver metastatic tumor, IMC-HA1 cells.
Leukemia
Immunochemistry of the Moloney MuLV gp71 molecule-1. Distribution of antigenic determinants on the products of digestion by Staphylococcus aureus protease.
Leukemia
Induction of mast cell activation and CC chemokine responses in remodeling tracheal allografts.
Leukemia
Induction of plasminogen activator by 12-O-tetradecanoylphorbol-13-acetate and calcium ionophore. Suppression by inhibitors of fatty acid lipoxygenase.
Leukemia
Inhibition of expression of natural UAG suppressor glutamine tRNA in HIV-infected human H9 cells in vitro by Avarol.
Leukemia
Inhibition of gamma-glutamyl transpeptidase activity at the surface of human myeloid cells is correlated with macrophage maturation and transforming growth factor beta production.
Leukemia
Inhibition of phorbol-ester-induced adhesion of differentiating human myeloid leukemic cells by pentamidine-isethionate.
Leukemia
Insulin-like growth factor binding protein-3 concentrations and insulin-like growth factor binding protein-3 protease activity in sera of patients with malignant solid tumors or leukemia.
Leukemia
Interactions of proteases and protease inhibitors in Sertoli-germ cell cocultures preceding the formation of specialized Sertoli-germ cell junctions in vitro.
Leukemia
Interplay between single resistance-associated mutations in the HIV-1 protease and viral infectivity, protease activity, and inhibitor sensitivity.
Leukemia
Isolation of glycopeptides containing individual glycosylation sites of Friend murine leukemia virus glycoprotein: studies of glycosylation by methylation analysis.
Leukemia
Leukemia inhibitory factor triggers activation of signal transducer and activator of transcription 3, proliferation, invasiveness, and altered protease expression in choriocarcinoma cells.
Leukemia
Lymphoid enhancer factor-1 links two hereditary leukemia syndromes through core-binding factor alpha regulation of ELA2.
Leukemia
Met-ase: cloning and distinct chromosomal location of a serine protease preferentially expressed in human natural killer cells.
Leukemia
Molecular and enzymatic characterization of the porcine endogenous retrovirus protease.
Leukemia
Moloney murine leukemia virus protease: bacterial expression and characterization of the purified enzyme.
Leukemia
Murine leukemia virus maturation: protease region required for conversion from "immature" to "mature" core form and for virus infectivity.
Leukemia
Murine leukemia virus protease is encoded by the gag-pol gene and is synthesized through suppression of an amber termination codon.
Leukemia
Natural UAG suppressor glutamine tRNA is elevated in mouse cells infected with Moloney murine leukemia virus.
Leukemia
Neutrophil elastase produces 52-kD and 30-kD glucocorticoid receptor fragments in the cytosol of human leukemia cells.
Leukemia
NMR study of xenotropic murine leukemia virus-related virus protease in a complex with amprenavir.
Leukemia
Novel MMP-9 substrates in cancer cells revealed by a label-free quantitative proteomics approach.
Leukemia
Phosphatidylserine externalization is a downstream event of interleukin-1 beta-converting enzyme family protease activation during apoptosis.
Leukemia
Phosphorylated forms of activated caspases are present in cytosol from HL-60 cells during etoposide-induced apoptosis.
Leukemia
PIG7 promotes leukemia cell chemosensitivity via lysosomal membrane permeabilization.
Leukemia
Protease inhibitor 10 inhibits tumor necrosis factor alpha -induced cell death. Evidence for the formation of intracellular high M(r) protease inhibitor 10-containing complexes.
Leukemia
Protease inhibitor-induced apoptosis: accumulation of wt p53, p21WAF1/CIP1, and induction of apoptosis are independent markers of proteasome inhibition.
Leukemia
Proteinase-3, a serine protease which mediates doxorubicin-induced apoptosis in the HL-60 leukemia cell line, is downregulated in its doxorubicin-resistant variant.
Leukemia
Purging effect of dibutyl phthalate on leukemia cells involves fas independent activation of caspase-3/CPP32 protease.
Leukemia
Purification and cloning of a novel serine protease, RNK-Met-1, from the granules of a rat natural killer cell leukemia.
Leukemia
Purification and cloning of a novel serine protease, RNK-Tryp-2, from the granules of a rat NK cell leukemia.
Leukemia
Rapid reversion of a deletion mutation in Moloney murine leukemia virus by recombination with a closely related endogenous provirus.
Leukemia
Regulation of myeloblastin messenger RNA expression in myeloid leukemia cells treated with all-trans retinoic acid.
Leukemia
Single cell multiplexed assay for proteolytic activity using droplet microfluidics.
Leukemia
Specific cleavage of recombinant protein tau3 between valine-220 and tyrosine-221 (val-309 and tyr-310 of tau4) by a double-stranded DNA-stimulated protease.
Leukemia
Structural and biochemical characterization of the inhibitor complexes of xenotropic murine leukemia virus-related virus protease.
Leukemia
Structural Characterization of the Loop at the Alpha-Subunit C-Terminus of the Mixed Lineage Leukemia Protein Activating Protease Taspase1.
Leukemia
Structure of the oligosaccharides sensitive to endo-beta-n-acetylglucosaminidase H in the glycoprotein of Friend murine leukemia virus.
Leukemia
Suppression of ADAM17-mediated Lyn/Akt pathways induces apoptosis of human leukemia U937 cells: Bungarus multicinctus protease inhibitor-like protein-1 uncovers the cytotoxic mechanism.
Leukemia
Survivin and EPR-1 expression in acute leukemias: Prognostic significance and review of the literature.
Leukemia
Targeting the cytotoxicity of fusogenic membrane glycoproteins in gliomas through protease-substrate interaction.
Leukemia
Taspase1 functions as a non-oncogene addiction protease that coordinates cancer cell proliferation and apoptosis.
Leukemia
The 10 C-terminal residues of HTLV-I protease are not necessary for enzymatic activity.
Leukemia
The decreased growth performance and impaired immune function and structural integrity by dietary iron deficiency or excess are associated with TOR, NF-?B, p38MAPK, Nrf2 and MLCK signaling in head kidney, spleen and skin of grass carp (Ctenopharyngodon idella).
Leukemia
The glycoprotein 71 of ecotropic Friend murine leukemia virus. Structure of the oligosaccharides linked to asparagine-12.
Leukemia
The Relationship between Vascular Endothelial Growth Factor 1154G/A Polymorphism and Recurrent Implantation Failure.
Leukemia
The targetable role of herpes virus-associated ubiquitin-specific protease (HAUSP) in p190 BCR-ABL leukemia.
Leukemia
Translational readthrough of an amber termination codon during synthesis of feline leukemia virus protease.
Leukemia
Ubiquitin-specific protease 22 acts as an oncoprotein to maintain glioma malignancy through deubiquitinating B cell-specific Moloney murine leukemia virus integration site 1 for stabilization.
Leukemia
Upregulation of Interferon-alpha and RANTES in the Cervix of HIV-1-Seronegative Women With High-Risk Behavior.
Leukemia
Urinary trypsin-inhibitor protects neutrophil chemotaxis in the inflammatory response.
Leukemia
[Comparisons of the characteristics and mechanisms of HBV replication in QSG-7701 and HepG2 cell lines]
Leukemia
[Effect of translocation t(15;17) on the gene expression regulation of myeloblastin during all trans retinoic acid induced myeloid differentiation in human leukemic cells]
Leukemia
[Transient hypofibrinogenemia induced by prednisolone in a case of acute lymphoblastic leukemia]
Leukemia, Erythroblastic, Acute
A soluble ATP-dependent system for protein degradation from murine erythroleukemia cells. Evidence for a protease which requires ATP hydrolysis but not ubiquitin.
Leukemia, Erythroblastic, Acute
Expression of protease activated receptor 3 (PAR3) is upregulated by induction of megakaryocyte phenotype in human erythroleukemia (HEL) cells.
Leukemia, Erythroblastic, Acute
The human proteinase-activated receptor-3 (PAR-3) gene. Identification within a Par gene cluster and characterization in vascular endothelial cells and platelets.
Leukemia, Feline
Translational readthrough of an amber termination codon during synthesis of feline leukemia virus protease.
Leukemia, Large Granular Lymphocytic
Constitutive expression of cytotoxic proteases and down-regulation of protease inhibitors in LGL leukemia.
Leukemia, Large Granular Lymphocytic
Purification and cloning of a novel serine protease, RNK-Met-1, from the granules of a rat natural killer cell leukemia.
Leukemia, Large Granular Lymphocytic
Purification and cloning of a novel serine protease, RNK-Tryp-2, from the granules of a rat NK cell leukemia.
Leukemia, Lymphocytic, Chronic, B-Cell
A protease-resistant immunotoxin against CD22 with greatly increased activity against CLL and diminished animal toxicity.
Leukemia, Lymphocytic, Chronic, B-Cell
Caspase-independent type III programmed cell death in chronic lymphocytic leukemia: the key role of the F-actin cytoskeleton.
Leukemia, Lymphocytic, Chronic, B-Cell
Immunolocalization of the ICE/Ced-3-family protease, CPP32 (Caspase-3), in non-Hodgkin's lymphomas, chronic lymphocytic leukemias, and reactive lymph nodes.
Leukemia, Lymphocytic, Chronic, B-Cell
Induction of an apoptotic program in cell-free extracts by 2-chloro-2'-deoxyadenosine 5'-triphosphate and cytochrome c.
Leukemia, Lymphocytic, Chronic, B-Cell
Protease activation and glucocorticoid-induced apoptosis in chronic lymphocytic leukemia.
Leukemia, Lymphocytic, Chronic, B-Cell
[Accessory use of protease-inhibiting agents for disease remission in a patient with autoimmune hemolytic anemia associated with B-CLL]
Leukemia, Lymphoid
Antitumor agents. XXXIV: Mechanism of action of bruceoside A and brusatol on nucleic acid metabolism of P-388 lymphocytic leukemia cells.
Leukemia, Megakaryoblastic, Acute
Apoptosis of Mo7e leukemia cells is associated with the cleavage of Bcl-2 into a shortened fragment that is not functional for heterodimerization with Bcl-2 and Bax.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Expression of the leukemic prognostic marker CD7 is linked to epigenetic modifications in chronic myeloid leukemia.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Midgut transcriptomal response of the rice leaffolder, Cnaphalocrocis medinalis (Guenée) to Cry1C toxin.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
The effects of saquinavir on imatinib-resistant chronic myelogenous leukemia cell lines.
Leukemia, Myeloid
Aspartate-based inhibitor of interleukin-1 beta-converting enzyme prevents antitumor agent-induced apoptosis in human myeloid leukemia U937 cells.
Leukemia, Myeloid
Bcl-xL overexpression inhibits taxol-induced Yama protease activity and apoptosis.
Leukemia, Myeloid
Caffeic acid phenethyl ester induces E2F-1-mediated growth inhibition and cell cycle arrest in human cervical cancer cells.
Leukemia, Myeloid
Changes in protease during differentiation of mouse myeloid leukemia cells.
Leukemia, Myeloid
Cytokine suppression of protease activation in wild-type p53-dependent and p53-independent apoptosis.
Leukemia, Myeloid
Proteinase-3, a serine protease which mediates doxorubicin-induced apoptosis in the HL-60 leukemia cell line, is downregulated in its doxorubicin-resistant variant.
Leukemia, Myeloid
[The mechanism of apoptosis induced by anticancer agents in human leukemia cells]
Leukemia, Myeloid, Acute
A novel and cytogenetically cryptic t(7;21)(p22;q22) in acute myeloid leukemia results in fusion of RUNX1 with the ubiquitin-specific protease gene USP42.
Leukemia, Myeloid, Acute
A novel specific cleavage of I?B? protein in acute myeloid leukemia cells involves protease PR3.
Leukemia, Myeloid, Acute
AML1-ETO targets and suppresses cathepsin G, a serine protease, which is able to degrade AML1-ETO in t(8;21) acute myeloid leukemia.
Leukemia, Myeloid, Acute
Cathepsin G Is Expressed by Acute Lymphoblastic Leukemia and Is a Potential Immunotherapeutic Target.
Leukemia, Myeloid, Acute
Changes in plasma levels of protease and fibrinolytic inhibitors induced by treatment in acute myeloid leukemia.
Leukemia, Myeloid, Acute
Demonstration of granulocytic proteases in plasma of patients with acute leukemia and septicemia with coagulation defects.
Leukemia, Myeloid, Acute
Evaluation of Apaf-1 and procaspases-2, -3, -7, -8, and -9 as potential prognostic markers in acute leukemia.
Leukemia, Myeloid, Acute
Human THP-1 monocytic leukemic cells induced to undergo monocytic differentiation by bryostatin 1 are refractory to proteasome inhibitor-induced apoptosis.
Leukemia, Myeloid, Acute
Hydroquinone, a bioreactive metabolite of benzene, inhibits apoptosis in myeloblasts.
Leukemia, Myeloid, Acute
Inhibition of the Mitochondrial Protease ClpP as a Therapeutic Strategy for Human Acute Myeloid Leukemia.
Leukemia, Myeloid, Acute
Linking the SUMO protease SENP5 to neutrophil differentiation of AML cells.
Leukemia, Myeloid, Acute
Lymphoid enhancer factor-1 links two hereditary leukemia syndromes through core-binding factor alpha regulation of ELA2.
Leukemia, Myeloid, Acute
Overexpression of Bcl-2 or Bcl-xL inhibits Ara-C-induced CPP32/Yama protease activity and apoptosis of human acute myelogenous leukemia HL-60 cells.
Leukemia, Myeloid, Acute
Plasma levels of protease inhibitors in acute myeloid leukemia at the onset of the disease and during antiblastic therapy.
Leukemia, Myeloid, Acute
Plasminogen activator inhibitor-2 in patients with monocytic leukemia.
Leukemia, Myeloid, Acute
Protease inhibitor 10 inhibits tumor necrosis factor alpha -induced cell death. Evidence for the formation of intracellular high M(r) protease inhibitor 10-containing complexes.
Leukemia, Myeloid, Acute
The constitutive protease release by primary human acute myeloid leukemia cells.
Leukemia, Myeloid, Acute
The inositol 5-phosphatase SHIP is expressed as 145 and 135 kDa proteins in blood and bone marrow cells in vivo, whereas carboxyl-truncated forms of SHIP are generated by proteolytic cleavage in vitro.
Leukemia, Myelomonocytic, Chronic
Protease inhibitor 10 inhibits tumor necrosis factor alpha -induced cell death. Evidence for the formation of intracellular high M(r) protease inhibitor 10-containing complexes.
Leukemia, Promyelocytic, Acute
A novel acidic serine protease, ASPNJ inhibits proliferation, induces apoptosis and enhances chemo-susceptibility of acute promyelocytic leukemia cell.
Leukemia, Promyelocytic, Acute
A protease-resistant PML-RAR{alpha} has increased leukemogenic potential in a murine model of acute promyelocytic leukemia.
Leukemia, Promyelocytic, Acute
All-trans retinoic acid rapidly decreases cathepsin G synthesis and mRNA expression in acute promyelocytic leukemia.
Leukemia, Promyelocytic, Acute
Blockade of the Ubiquitin Protease UBP43 Destabilizes the Transcription Factor PML/RAR{alpha} and Inhibits Growth of Acute Promyelocytic Leukemia.
Leukemia, Promyelocytic, Acute
Differential regulation of sentrinized proteins by a novel sentrin-specific protease.
Leukemia, Promyelocytic, Acute
Inhibition of phorbol-ester-induced adhesion of differentiating human myeloid leukemic cells by pentamidine-isethionate.
Leukemia, Promyelocytic, Acute
Sudden death due to undiagnosed acute promyelocytic leukemia: a case report.
Leukemia, T-Cell
A novel protease processing site in the transframe protein of human T-cell leukemia virus type 1 PR76(gag-pro) defines the N terminus of RT.
Leukemia, T-Cell
Characterizing the protonation states of the catalytic residues in apo and substrate-bound human T-cell leukemia virus type 1 protease.
Leukemia, T-Cell
Chipping at large, potent human T-cell leukemia virus type 1 protease inhibitors to uncover smaller, equipotent inhibitors.
Leukemia, T-Cell
Complete nucleotide sequence of an infectious clone of human T-cell leukemia virus type II: an open reading frame for the protease gene.
Leukemia, T-Cell
Complete sequence of human T cell leukemia virus type 1 in ATLL patients from Northeast Iran, Mashhad revealed a prematurely terminated protease and an elongated pX open reading frame III.
Leukemia, T-Cell
Crystal structures of inhibitor complexes of human T-cell leukemia virus (HTLV-1) protease.
Leukemia, T-Cell
Efficient expression and rapid purification of human T-cell leukemia virus type 1 protease.
Leukemia, T-Cell
Expression of human T-cell leukemia virus type I protease in Escherichia coli.
Leukemia, T-Cell
HTLV-I protease cleavage of P19/24 substrates is not dependent on NaCl concentration.
Leukemia, T-Cell
Human T-cell leukemia virus type 1 protease protein expressed in Escherichia coli possesses aspartic proteinase activity.
Leukemia, T-Cell
Identification of a protease gene of human T-cell leukemia virus type I (HTLV-I) and its structural comparison.
Leukemia, T-Cell
Kinetic characterization of newly discovered inhibitors of various constructs of human T-cell leukemia virus-1 (HTLV-1) protease and their effect on HTLV-1-infected cells.
Leukemia, T-Cell
Molecular replacement with pseudosymmetry and model dissimilarity: a case study.
Leukemia, T-Cell
Narrow substrate specificity and sensitivity toward ligand-binding site mutations of human T-cell Leukemia virus type 1 protease.
Leukemia, T-Cell
Overexpression of Ubiquitin Specific Protease 44 (USP44) Induces Chromosomal Instability and Is Frequently Observed in Human T-Cell Leukemia.
Leukemia, T-Cell
Processing of gag precursor polyprotein of human T-cell leukemia virus type I by virus-encoded protease.
Leukemia, T-Cell
Purification and characterization of human T-cell leukemia virus type I protease produced in Escherichia coli.
Leukemia, T-Cell
Requirement of N- and C-terminal regions for enzymatic activity of human T-cell leukemia virus type I protease.
Leukemia, T-Cell
Reversible oxidative modification as a mechanism for regulating retroviral protease dimerization and activation.
Leukemia, T-Cell
The protease of human T-cell leukemia virus type-1 is a potential therapeutic target.
Leukemia, T-Cell
Total chemical synthesis of human T-cell leukemia virus type 1 protease via native chemical ligation.
Leukemia-Lymphoma, Adult T-Cell
Complete sequence of human T cell leukemia virus type 1 in ATLL patients from Northeast Iran, Mashhad revealed a prematurely terminated protease and an elongated pX open reading frame III.
Leukemia-Lymphoma, Adult T-Cell
Lactacystin activates FLICE (caspase 8) protease and induces apoptosis in Fas-resistant adult T-cell leukemia cell lines.
Leukemia-Lymphoma, Adult T-Cell
Preapoptotic protease calpain-2 is frequently suppressed in adult T-cell leukemia.
Leukocytosis
Cerebrospinal fluid viral escape in aviremic HIV-infected patients receiving antiretroviral therapy: prevalence, risk factors and neurocognitive effects.
Leukoencephalopathies
Distinct molecular mechanisms of HTRA1 mutants in manifesting heterozygotes with CARASIL.
Leukoencephalopathies
Evaluation of progressive multifocal leukoencephalopathy treatments in a Spanish cohort of HIV-infected patients: do protease inhibitors improve survival regardless of central nervous system penetration-effectiveness (CPE) score?
Leukoencephalopathies
Progressive multifocal leukoencephalopathy: improved survival of human immunodeficiency virus-infected patients in the protease inhibitor era.
Leukoencephalopathies
Progressive multifocal leukoencephalopathy: prolonged survival in patients treated with protease inhibitors and cidofovir: a case series.
Leukoencephalopathies
Prolonged survival without neurological improvement in patients with AIDS-related progressive multifocal leukoencephalopathy on potent combined antiretroviral therapy.
Leukoencephalopathies
Survival improvement of AIDS-related progressive multifocal leukoencephalopathy in the era of protease inhibitors. Clinical Epidemiology Group. French Hospital Database on HIV.
Leukoencephalopathies
The first Greek case of heterozygous cerebral autosomal recessive arteriopathy with subcortical infarcts and leukoencephalopathy: An atypical clinico-radiological presentation.
Leukoencephalopathy, Progressive Multifocal
Evaluation of progressive multifocal leukoencephalopathy treatments in a Spanish cohort of HIV-infected patients: do protease inhibitors improve survival regardless of central nervous system penetration-effectiveness (CPE) score?
Leukoencephalopathy, Progressive Multifocal
Progressive multifocal leukoencephalopathy: improved survival of human immunodeficiency virus-infected patients in the protease inhibitor era.
Leukoencephalopathy, Progressive Multifocal
Progressive multifocal leukoencephalopathy: prolonged survival in patients treated with protease inhibitors and cidofovir: a case series.
Leukoencephalopathy, Progressive Multifocal
Prolonged survival without neurological improvement in patients with AIDS-related progressive multifocal leukoencephalopathy on potent combined antiretroviral therapy.
Leukoencephalopathy, Progressive Multifocal
Survival improvement of AIDS-related progressive multifocal leukoencephalopathy in the era of protease inhibitors. Clinical Epidemiology Group. French Hospital Database on HIV.
Leukomalacia, Periventricular
Effect of moderate hypocapnic ventilation on nuclear DNA fragmentation and energy metabolism in the cerebral cortex of newborn piglets.
Leukoplakia, Oral
Clinical modulation of oral leukoplakia and protease activity by Bowman-Birk inhibitor concentrate in a phase IIa chemoprevention trial.
Leukoplakia, Oral
Development of the Bowman-Birk inhibitor for oral cancer chemoprevention and analysis of Neu immunohistochemical staining intensity with Bowman-Birk inhibitor concentrate treatment.
Leukoplakia, Oral
Relationship between protease activity and neu oncogene expression in patients with oral leukoplakia treated with the Bowman Birk Inhibitor.
Leukoplakia, Oral
The protease inhibitor, Bowman-Birk Inhibitor, suppresses experimental autoimmune encephalomyelitis: a potential oral therapy for multiple sclerosis.
Lewy Body Disease
Comparison of cathepsin protease activities in brain tissue from normal cases and cases with Alzheimer's disease, Lewy body dementia, Parkinson's disease and Huntington's disease.
Lichen Planus, Oral
Role of mammary serine protease inhibitor on the inflammatory response in oral lichen planus.
Lichen Sclerosus et Atrophicus
Isolation and partial characterization of an elastase-type protease in human vulva fibroblasts: its possible involvement in vulvar elastic tissue destruction of patients with lichen sclerosus et atrophicus.
Lipodystrophy
A randomized, double-blind study of gemfibrozil for the treatment of protease inhibitor-associated hypertriglyceridaemia.
Lipodystrophy
A randomized, placebo-controlled trial of rosiglitazone for HIV-related lipoatrophy.
Lipodystrophy
A syndrome of lipoatrophy, lactic acidaemia and liver dysfunction associated with HIV nucleoside analogue therapy: contribution to protease inhibitor-related lipodystrophy syndrome.
Lipodystrophy
A syndrome of peripheral lipodystrophy, hyperlipidaemia and insulin resistance in patients receiving HIV protease inhibitors.
Lipodystrophy
Absence of hypersensitivity to glucocorticoids in antiretroviral-associated lipodystrophy.
Lipodystrophy
Acute Myocardial Infarction in a 34-Year-Old HIV-Positive Female Patient While Undergoing Active Antiretroviral Therapy Containing a Protease Inhibitor.
Lipodystrophy
Adipocytokine dysregulation, abnormal glucose metabolism, and lipodystrophy in HIV-infected adolescents receiving protease inhibitors.
Lipodystrophy
Adipokine profiles and lipodystrophy in HIV-infected children during the first 4 years on highly active antiretroviral therapy.
Lipodystrophy
Altered myocellular and abdominal fat partitioning predict disturbance in insulin action in HIV protease inhibitor-related lipodystrophy.
Lipodystrophy
Antiretroviral protease inhibitor therapy leads to hyperglycaemia, hyperlipidaemia and lipodystrophy.
Lipodystrophy
Apoprotein c-III and E-containing lipoparticles are markedly increased in HIV-infected patients treated with protease inhibitors: association with the development of lipodystrophy.
Lipodystrophy
Assessment of the safety and efficacy of poly-L-lactic acid for the treatment of HIV-associated facial lipoatrophy.
Lipodystrophy
Association of APOC3 polymorphisms with both dyslipidemia and lipoatrophy in HAART-receiving patients.
Lipodystrophy
AVASCULAR NECROSIS OF THE FEMORAL HEAD IN HIV-INFECTED PATIENTS: PRELIMINARY RESULTS FROM SURGICAL TREATMENT FOR CERAMIC-CERAMIC JOINT REPLACEMENT.
Lipodystrophy
Benefit of switching from a protease inhibitor (PI) to nevirapine in PI-experienced patients suffering acquired HIV-related lipodystrophy syndrome (AHL): interim analysis at 3 months of follow-up.
Lipodystrophy
Blepharoptosis and external ophthalmoplegia associated with long-term antiretroviral therapy.
Lipodystrophy
Body composition changes in protease inhibitor-naive HIV-infected patients treated with two nucleoside reverse transcriptase inhibitors.
Lipodystrophy
Body fat and other metabolic effects of atazanavir and efavirenz, each administered in combination with zidovudine plus lamivudine, in antiretroviral-naive HIV-infected patients.
Lipodystrophy
Cardiovascular risk and dyslipidemia among persons living with HIV: a review.
Lipodystrophy
Cellular Mechanism Underlying Highly-Active or Antiretroviral Therapy-Induced Lipodystrophy: Atazanavir, a Protease Inhibitor, Compromises Adipogenic Conversion of Adipose-Derived Stem/Progenitor Cells through Accelerating ER Stress-Mediated Cell Death in Differentiating Adipocytes.
Lipodystrophy
Cutaneous effects of highly active antiretroviral therapy in HIV-infected patients.
Lipodystrophy
Cutaneous toxicities of antiretroviral therapy for HIV: part I. Lipodystrophy syndrome, nucleoside reverse transcriptase inhibitors, and protease inhibitors.
Lipodystrophy
Diabetes, insulin resistance and dyslipidaemia in lipodystrophic HIV-infected patients on highly active antiretroviral therapy (HAART).
Lipodystrophy
Diagnosis, prediction, and natural course of HIV-1 protease-inhibitor-associated lipodystrophy, hyperlipidaemia, and diabetes mellitus: a cohort study.
Lipodystrophy
Different origin of adipogenic stem cells influences the response to antiretroviral drugs.
Lipodystrophy
Disorders of glucose metabolism in the context of human immunodeficiency virus infection.
Lipodystrophy
Dyslipidaemia associated with antiretroviral therapy in HIV-infected patients.
Lipodystrophy
Effect of L-Acetylcarnitine on Body Composition in HIV-related Lipodystrophy.
Lipodystrophy
Effect of pravastatin on body composition and markers of cardiovascular disease in HIV-infected men-a randomized, placebo-controlled study.
Lipodystrophy
Effects of antiretroviral drug combinations on the differentiation of adipocytes.
Lipodystrophy
Effects of metformin or gemfibrozil on the lipodystrophy of HIV-infected patients receiving protease inhibitors.
Lipodystrophy
Effects of protease inhibitors on hyperglycemia, hyperlipidemia, and lipodystrophy: a 5-year cohort study.
Lipodystrophy
Effects of troglitazone on insulin sensitivity in HIV-infected patients with protease inhibitor-associated diabetes mellitus.
Lipodystrophy
Endocrine and metabolic disorders associated with human immune deficiency virus infection.
Lipodystrophy
Endocrine and metabolic evaluation of human immunodeficiency virus-infected patients with evidence of protease inhibitor-associated lipodystrophy.
Lipodystrophy
Endoplasmic reticulum stress links dyslipidemia to inhibition of proteasome activity and glucose transport by HIV protease inhibitors.
Lipodystrophy
Epidural spinal lipomatosis with acute onset of paraplegia in an HIV-positive patient treated with corticosteroids and protease inhibitor: case report.
Lipodystrophy
Evaluation of the risk factors associated with lipodystrophy development in a cohort of HIV-positive patients.
Lipodystrophy
Evidence of human immunodeficiency virus-associated lipodystrophy syndrome in children treated with protease inhibitors.
Lipodystrophy
Exercise Training in HIV-1-Infected Individuals with Dyslipidemia and Lipodystrophy.
Lipodystrophy
Exploring the pathophysiology behind the more common genetic and acquired lipodystrophies.
Lipodystrophy
Fat distribution and metabolic changes are strongly correlated and energy expenditure is increased in the HIV lipodystrophy syndrome.
Lipodystrophy
Fat distribution is altered in HIV-infected men without clinical evidence of the HIV lipodystrophy syndrome.
Lipodystrophy
Features of Metabolic Syndrome and Its Associated Factors during Highly Active Antiretroviral Therapy in Ouagadougou (Burkina Faso).
Lipodystrophy
Glycaemic consequences of HIV and highly active antiretroviral therapy: a pilot study and review of literature.
Lipodystrophy
Glycaemic profile changes by highly active antiretroviral therapy in human immunodeficiency virus-infected patients.
Lipodystrophy
Gynecomastia, lipodystrophy syndrome, and dyslipidemia occurring or worsening during antiretroviral regimens other than protease inhibitor-based ones.
Lipodystrophy
HIV medicine after Barcelona conference: interview with Howard Grossman, M.D. Interview by John S. James.
Lipodystrophy
HIV protease inhibitor induces fatty acid and sterol biosynthesis in liver and adipose tissues due to the accumulation of activated sterol regulatory element-binding proteins in the nucleus.
Lipodystrophy
HIV protease inhibitor substitution in patients with lipodystrophy: a randomized, controlled, open-label, multicentre study.
Lipodystrophy
HIV protease inhibitors protect apolipoprotein B from degradation by the proteasome: a potential mechanism for protease inhibitor-induced hyperlipidemia.
Lipodystrophy
How best to approach endocrine evaluation in patients with HIV in the era of combined antiretroviral therapy?
Lipodystrophy
Impact of HAART exposure and associated lipodystrophy on advanced liver fibrosis in HIV/HCV-coinfected patients.
Lipodystrophy
Impact of protease inhibitor substitution with efavirenz in HIV-infected children: results of the First Pediatric Switch Study.
Lipodystrophy
Impact of switching from human immunodeficiency virus type 1 protease inhibitors to efavirenz in successfully treated adults with lipodystrophy.
Lipodystrophy
In combination, nucleoside reverse transcriptase inhibitors have significant effects on 3T3-L1 adipocyte lipid accumulation and survival.
Lipodystrophy
In vitro evidence of inhibition of mitochondrial protease processing by HIV-1 protease inhibitors in yeast: a possible contribution to lipodystrophy syndrome.
Lipodystrophy
Incidence and risk factors for mitochondrial toxicity in treated HIV/HCV-coinfected patients.
Lipodystrophy
Increased abdominal visceral fat is associated with reduced bone density in HIV-infected men with lipodystrophy.
Lipodystrophy
Increased risk of lipodystrophy when nucleoside analogue reverse transcriptase inhibitors are included with protease inhibitors in the treatment of HIV-1 infection.
Lipodystrophy
Indinavir inhibits sterol-regulatory element-binding protein-1c-dependent lipoprotein lipase and fatty acid synthase gene activations.
Lipodystrophy
Kager's fat pad inflammation associated with HIV infection and AIDS: MRI findings.
Lipodystrophy
Leptin replacement therapy but not dietary polyunsaturated fatty acid alleviates HIV protease inhibitor-induced dyslipidemia and lipodystrophy in mice.
Lipodystrophy
Lipodystrophy and altered body shape in HIV: a protease inhibitor side effect? What do you tell your patient?
Lipodystrophy
Lipodystrophy defined by a clinical score in HIV-infected men on highly active antiretroviral therapy: correlation between dyslipidaemia and steroid hormone alterations.
Lipodystrophy
Lipodystrophy diagnosis in people living with HIV/AIDS: prediction and validation of sex-specific anthropometric models.
Lipodystrophy
Lipodystrophy in 685 HIV-1-treated patients: influence of antiretroviral treatment and immunovirological response.
Lipodystrophy
Lipodystrophy in children and adolescents with acquired immunodeficiency syndrome and its relationship with the antiretroviral therapy employed.
Lipodystrophy
Lipodystrophy in HIV-1-positive patients is associated with insulin resistance in multiple metabolic pathways.
Lipodystrophy
Lipodystrophy in HIV-infected children is associated with high viral load and low CD4+ -lymphocyte count and CD4+ -lymphocyte percentage at baseline and use of protease inhibitors and stavudine.
Lipodystrophy
Lipodystrophy in HIV-infected pediatric patients receiving protease inhibitors.
Lipodystrophy
Lipodystrophy in patients with HIV-1 infection: effect of stopping protease inhibitors on TNF-alpha and TNF-receptor levels, and on metabolic parameters.
Lipodystrophy
Lipodystrophy syndrome among HIV infected children on highly active antiretroviral therapy in northern India.
Lipodystrophy
Lipodystrophy-associated morphological, cholesterol and triglyceride abnormalities in a population-based HIV/AIDS treatment database.
Lipodystrophy
Low prevalence of lipodystrophy in HIV-infected Senegalese children on long-term antiretroviral treatment: the ANRS 12279 MAGGSEN Pediatric Cohort Study.
Lipodystrophy
Markedly diminished lipolysis and partial restoration of glucose metabolism, without changes in fat distribution after extended discontinuation of protease inhibitors in severe lipodystrophic human immunodeficient virus-1-infected patients.
Lipodystrophy
Mechanisms of antiretroviral-induced mitochondrial dysfunction in adipocytes and adipose tissue: in-vitro, animal and human adipose tissue studies.
Lipodystrophy
Metabolic and neurologic consequences of chronic lopinavir/ritonavir administration to C57BL/6 mice.
Lipodystrophy
Metabolic complications affecting adipose tissue, lipid and glucose metabolism associated with HIV antiretroviral treatment.
Lipodystrophy
Metabolic disorders among HIV-infected patients treated with protease inhibitors: a review.
Lipodystrophy
Metabolic response to a C-glucose load in human immunodeficiency virus patients before and after antiprotease therapy.
Lipodystrophy
Microarray Analysis Reveals Altered Lipid and Glucose Metabolism Genes in Differentiated, Ritonavir-Treated 3T3-L1 Adipocytes.
Lipodystrophy
Minireview: weapons of lean body mass destruction: the role of ectopic lipids in the metabolic syndrome.
Lipodystrophy
Mitochondrial subhaplogroups and differential risk of stavudine-induced lipodystrophy in Malawian HIV/AIDS patients.
Lipodystrophy
Novel Approaches to Targeting Visceral and Hepatic Adiposities in HIV-Associated Lipodystrophy.
Lipodystrophy
Overcoming obstacles to the success of protease inhibitors in highly active antiretroviral therapy regimens.
Lipodystrophy
Plasmapheresis in the treatment of an acute pancreatitis due to protease inhibitor-induced hypertriglyceridemia.
Lipodystrophy
Protease inhibitor therapy-associated lipodystrophy, hypertriglyceridaemia and diabetes mellitus.
Lipodystrophy
Protease inhibitor treatments reveal specific involvement of matrix metalloproteinase-9 in human adipocyte differentiation.
Lipodystrophy
Protease inhibitors in HIV infection. Lipodystrophy may be a consequence of prolonged survival.
Lipodystrophy
Rationale and clinical utility of the darunavir-cobicistat combination in the treatment of HIV/AIDS.
Lipodystrophy
Regression of lipodystrophy in HIV-infected patients under therapy with the new protease inhibitor atazanavir.
Lipodystrophy
Relationship between dietary intake and use of protease inhibitors with anthropometric and biochemical parameters of lipodystrophy in people living with hiv.
Lipodystrophy
Respiratory failure associated with the lipodystrophy syndrome in an HIV-positive patient with compromised lung function.
Lipodystrophy
Reversal of atherogenic lipoprotein profile in HIV-1 infected patients with lipodystrophy after replacing protease inhibitors by nevirapine.
Lipodystrophy
Risk factors for sexual and erectile dysfunction in HIV-infected men: the role of protease inhibitors.
Lipodystrophy
Risk of lipodystrophy in HIV-1-infected patients treated with protease inhibitors: a prospective cohort study.
Lipodystrophy
Ste24: An Integral Membrane Protein Zinc Metalloprotease with Provocative Structure and Emergent Biology.
Lipodystrophy
Syndrome of lipodystrophy, hyperlipidemia, insulin resistance, and diabetes in treated patients with human immunodeficiency virus infection.
Lipodystrophy
The development of lipodystrophy on a protease inhibitor-sparing highly active antiretroviral therapy regimen.
Lipodystrophy
The HIV protease inhibitor indinavir impairs sterol regulatory element-binding protein-1 intranuclear localization, inhibits preadipocyte differentiation, and induces insulin resistance.
Lipodystrophy
The HIV protease inhibitor saquinavir impairs lipid metabolism and glucose transport in cultured adipocytes.
Lipodystrophy
The mechanism of insulin resistance caused by HIV protease inhibitor therapy.
Lipodystrophy
The role of diet, exercise and smoking in dyslipidaemia in HIV-infected patients with lipodystrophy.
Lipodystrophy
The SWITCHMRK studies: substitution of lopinavir/ritonavir with raltegravir in HIV-positive individuals.
Lipodystrophy
Treatment with protease inhibitors associated with peripheral insulin resistance and impaired oral glucose tolerance in HIV-1-infected patients.
Lipodystrophy
Tuberous and tendinous xanthomata secondary to ritonavir-associated hyperlipidemia.
Lipodystrophy
Upregulation of nuclear-encoded mitochondrial LON protease in HAART-treated HIV-positive patients with lipodystrophy: implications for the pathogenesis of the disease.
Lipodystrophy
Validation by simulation of a clinical trial model using the standardized mean and variance criteria.
Lipodystrophy
["Buffalo neck": an unintended secondary effect of treatment with anti-HIV protease inhibitors]
Lipodystrophy
[Acute myocardial infarct in HIV-positive patients in treatment with protease inhibitors]
Lipodystrophy
[Lipodystrophy and 'buffalo hump' during treatment with HIV protease inhibitors]
Lipodystrophy
[Lipodystrophy and lipid metabolism alterations in HIV-infected patients receiving highly active antiretroviral therapy (HAART)]
Lipodystrophy
[Lipodystrophy: a complication of protease inhibitors in HIV seropositive patients]
Lipodystrophy
[Metabolic disorders and lipodystrophy. Adverse effects of antiretroviral therapy]
Lipodystrophy
[Outcome of hyperlactatemia and lipodystrophy syndromes in patients infected with human immunodeficiency virus]
Lipoma
LMNA mutations induce a non-inflammatory fibrosis and a brown fat-like dystrophy of enlarged cervical adipose tissue.
Lipoma
Multiple subcutaneous lipomas induced by HAART in the absence of protease inhibitors.
Lipomatosis
Epidural spinal lipomatosis with acute onset of paraplegia in an HIV-positive patient treated with corticosteroids and protease inhibitor: case report.
Lipomatosis
Parotid lipomatosis in HIV positive patients: a new clinical disorder associated with protease inhibitors.
Lipomatosis
Spinal epidural lipomatosis in a human immunodeficiency virus-positive patient receiving steroids and protease inhibitor therapy.
Lissencephaly
LONP1 de novo dominant mutation causes mitochondrial encephalopathy with loss of LONP1 chaperone activity and excessive LONP1 proteolytic activity.
Liver Cirrhosis
A Lead-In with Silibinin Prior to Triple-Therapy Translates into Favorable Treatment Outcomes in Difficult-To-Treat HIV/Hepatitis C Coinfected Patients.
Liver Cirrhosis
A novel role of glutathione S-transferase A3 in inhibiting hepatic stellate cell activation and rat hepatic fibrosis.
Liver Cirrhosis
A reduced grade of liver fibro-steatosis after raltegravir, maraviroc and fosamprenavir in an HIV/HCV co-infected patient with chronic hepatitis, cardiomyopathy, intolerance to nelfinavir and a marked increase of serum creatine phosphokinase levels probably related to integrase inhibitor use.
Liver Cirrhosis
alpha 1-antitrypsin deficiency detection by direct analysis of the mutation in the gene.
Liver Cirrhosis
Analysis of the substrate specificity of Factor VII activating protease (FSAP) and design of specific and sensitive peptide substrates.
Liver Cirrhosis
Antiretroviral therapy based on protease inhibitors as a protective factor against liver fibrosis progression in patients with chronic hepatitis C.
Liver Cirrhosis
Association between exposure to nevirapine and reduced liver fibrosis progression in patients with HIV and hepatitis C virus coinfection.
Liver Cirrhosis
Association of Hepatitis B Core-Related Antigen and Antihepatitis B Core Antibody With Liver Fibrosis Evolution in Human Immunodeficiency Virus-Hepatitis B Virus Coinfected Patients During Treatment With Tenofovir.
Liver Cirrhosis
Changes in the catalytic activities of proteoglycan-degrading lysosomal enzymes in parenchymal and non-parenchymal liver cells and in serum during the development of experimental liver fibrosis.
Liver Cirrhosis
Effect of antiretroviral drugs on liver fibrosis in HIV-infected patients with chronic hepatitis C: harmful impact of nevirapine.
Liver Cirrhosis
Effect of the protease inhibitor MG132 on the transforming growth factor-?/Smad signaling pathway in HSC-T6 cells.
Liver Cirrhosis
Effect of the serine protease inhibitor, aprotinin, on systemic haemodynamics and renal function in patients with hepatic cirrhosis and ascites.
Liver Cirrhosis
Efficacy of lead-in silibinin and subsequent triple therapy in difficult-to-treat HIV/hepatitis C virus-coinfected patients.
Liver Cirrhosis
Endothelial cell toll-like receptor 4 regulates fibrosis-associated angiogenesis in the liver.
Liver Cirrhosis
Exposure to previous cART is associated with significant liver fibrosis and cirrhosis in human immunodeficiency virus-infected patients.
Liver Cirrhosis
Factors affecting liver fibrosis in human immunodeficiency virus-and hepatitis C virus-coinfected patients: impact of protease inhibitor therapy.
Liver Cirrhosis
Immunological and functional determination of the protease inhibitors, protein C and antithrombin III, in liver cirrhosis and in neoplasia.
Liver Cirrhosis
Impact of HAART exposure and associated lipodystrophy on advanced liver fibrosis in HIV/HCV-coinfected patients.
Liver Cirrhosis
Increased plasma cathepsin D concentration in hepatic carcinoma and cirrhosis but not in breast cancer.
Liver Cirrhosis
LAP degradation product reflects plasma kallikrein-dependent TGF-? activation in patients with hepatic fibrosis.
Liver Cirrhosis
Liver cirrhosis associated with heterozygous alpha-1-antitrypsin deficiency type Pi MS and autoimmune features.
Liver Cirrhosis
Liver Fibrosis in HCV Monoinfected and HIV/HCV Coinfected Patients: Dysregulation of Matrix Metalloproteinases (MMPs) and Their Tissue Inhibitors TIMPs and Effect of HCV Protease Inhibitors.
Liver Cirrhosis
nonalcoholic fatty liver disease diagnosed by transient elastography with controlled attenuation parameter in unselected HIV mono-infected patients.
Liver Cirrhosis
Novel pathomechanism for spontaneous bacterial peritonitis: disruption of cell junctions by cellular and bacterial proteases.
Liver Cirrhosis
Performance of two HCV RNA assays during protease inhibitor-based triple therapy in patients with advanced liver fibrosis and cirrhosis.
Liver Cirrhosis
Polymorphisms of ?1-antitrypsin and Interleukin-6 genes and the progression of hepatic cirrhosis in patients with a hepatitis C virus infection.
Liver Cirrhosis
Preventive effect of urinary trypsin inhibitor on the development of liver fibrosis in mice.
Liver Cirrhosis
Progression of Liver Fibrosis and Modern Combination Antiretroviral Therapy Regimens in HIV-Hepatitis C-Coinfected Persons.
Liver Cirrhosis
Progression of liver fibrosis in patients coinfected with hepatitis C virus and human immunodeficiency virus undergoing antiretroviral therapy.
Liver Cirrhosis
Protease profiling of liver fibrosis reveals the adam metallopeptidase with thrombospondin type 1 motif, 1 as a central activator of TGF-?
Liver Cirrhosis
Proteome analysis of testis from infertile protein C inhibitor-deficient mice reveals novel changes in serpin processing and prostaglandin metabolism.
Liver Cirrhosis
Renal outcomes after up to eight years of tenofovir exposure in HIV-HBV-coinfected patients.
Liver Cirrhosis
Serine Protease HtrA2/Omi Deficiency Impairs Mitochondrial Homeostasis and Promotes Hepatic Fibrogenesis via Activation of Hepatic Stellate Cells.
Liver Cirrhosis
Serum markers of liver fibrosis: combining the BIPED classification and the neo-epitope approach in the development of new biomarkers.
Liver Cirrhosis
The Coagulation System Contributes to {alpha}V{beta}6 Integrin Expression and Liver Fibrosis Induced by Cholestasis.
Liver Cirrhosis
The effect of ulinastatin pre-treatment on vecuronium-induced neuromuscular block in patients with hepatic cirrhosis.
Liver Cirrhosis
The shapes of Z-?1-antitrypsin polymers in solution support the C-terminal domain-swap mechanism of polymerization.
Liver Cirrhosis
USP18 downregulation in peripheral blood mononuclear cells predicts nonresponse to interferon-based triple therapy in patients with chronic hepatitis C, genotype 1: a pilot study.
Liver Cirrhosis
[Changes of mast cells and protease activated receptor-2 in experimental rat liver fibrosis]
Liver Cirrhosis
[Gene therapy for liver fibrosis using genes that code for protease matrices]
Liver Cirrhosis
[Postoperative change of serum protease inhibitor and C-reactive protein level--with special reference to surgical resection of liver cirrhosis]
Liver Cirrhosis
[The progression of liver fibrosis in prison inmates co-infected by HIV and HCV who started on boosted protease inhibitor therapy].
Liver Cirrhosis
[The protease inhibitor treatment of the disseminated intravascular coagulation syndrome in patients with liver cirrhosis]
Liver Diseases
A Library of Rare ?1-Antitrypsin (AAT) Variant Phenotypes to Aid in the Diagnosis of AAT Deficiency.
Liver Diseases
A patient with the rare alpha-1-antitrypsin variant Zbristol in compound heterozygosity with the Z mutation.
Liver Diseases
A polymorphism of the alpha1-antitrypsin gene represents a risk factor for liver disease.
Liver Diseases
A rare variant of alpha 1 antitrypsin mutations detected in Vietnamese children with liver disease.
Liver Diseases
A syndrome of lipoatrophy, lactic acidaemia and liver dysfunction associated with HIV nucleoside analogue therapy: contribution to protease inhibitor-related lipodystrophy syndrome.
Liver Diseases
Activated protein C prevents multiple organ injury following extensive hepatectomy in cirrhotic rats.
Liver Diseases
ADD66, a gene involved in the endoplasmic reticulum-associated degradation of alpha-1-antitrypsin-Z in yeast, facilitates proteasome activity and assembly.
Liver Diseases
Advanced liver fibrosis in HIV/HCV-coinfected patients on antiretroviral therapy.
Liver Diseases
Alpha 1-antitrypsin deficiency and the PiMS phenotype: case report and literature review.
Liver Diseases
Alpha1-antitrypsin deficiency and liver disease in children: phenotypes, manifestations, and prognosis.
Liver Diseases
Alterations in C1 inhibitor and clotting factor concentrations in primary biliary cirrhosis and other chronic liver diseases.
Liver Diseases
Amelioration of Alpha-1 Antitrypsin Deficiency Diseases with Genome Editing in Transgenic Mice.
Liver Diseases
Contribution of sinusoidal endothelial liver cells to liver fibrosis: expression of transforming growth factor-beta 1 receptors and modulation of plasmin-generating enzymes by transforming growth factor-beta 1.
Liver Diseases
Current management and perspectives for HCV recurrence after liver transplantation.
Liver Diseases
Deciding on Interferon-Free Treatment for Chronic Hepatitis C: Updating Liver Stiffness Cut-Off Values to Maximize Benefit.
Liver Diseases
Evidence for the presence of an inactive precursor of human hepatocyte growth factor in plasma and sera of patients with liver diseases.
Liver Diseases
Factors associated with statin selection among privately insured commercial and Medicare patients.
Liver Diseases
Fatal liver disease associated with alpha 1-antitrypsin deficiency PiM1/PiMduarte.
Liver Diseases
Genome-wide analysis of health-related biomarkers in the UK Household Longitudinal Study reveals novel associations.
Liver Diseases
HCV protease inhibitory, cytotoxic and apoptosis-inducing effects of oleanolic acid derivatives.
Liver Diseases
Identification of a novel SERPINA-1 mutation causing alpha-1 antitrypsin deficiency in a patient with severe bronchiectasis and pulmonary embolism.
Liver Diseases
Impact of Antiretroviral Treatment-Related Toxicities on Hospital Admissions in HIV-Infected Patients.
Liver Diseases
Impact of highly active antiretroviral therapy on the spectrum of liver disease in HCV-HIV coinfection.
Liver Diseases
Impact of specialty pharmacy on telaprevir-containing 3-drug hepatitis C regimen persistence.
Liver Diseases
Improvement in liver steatosis after the switch from a ritonavir-boosted protease inhibitor to raltegravir in HIV-infected patients with non-alcoholic fatty liver disease.
Liver Diseases
Is it appropriate to study blood ghrelin and obestatin in non-alcoholic fatty liver disease (NAFLD) without using protease inhibitors?
Liver Diseases
Limited effectiveness and safety profile of protease inhibitor-based triple therapy against chronic hepatitis C in a real-world cohort with a high proportion of advanced liver disease.
Liver Diseases
Liver Fat, Adipose Tissue, and Body Composition Changes After Switching from a Protease Inhibitor or Efavirenz to Raltegravir.
Liver Diseases
Monoallelic expression of the protease inhibitor gene in humans, sheep, and cattle.
Liver Diseases
Natural history and predictors of severity of chronic hepatitis C virus (HCV) and human immunodeficiency virus (HIV) co-infection.
Liver Diseases
Neutrophil and Monocyte Function in Patients with Chronic Hepatitis C Undergoing Antiviral Therapy with Regimens Containing Protease Inhibitors with and without Interferon.
Liver Diseases
Polymorphism in the endoplasmic reticulum mannosidase I (MAN1B1) gene is not associated with liver disease in individuals homozygous for the Z variant of the alpha1-antitrypsin protease inhibitor (PiZZ individuals).
Liver Diseases
Protease inhibitor-based direct-acting antivirals are associated with increased risk of aminotransferase elevations but not hepatic dysfunction or decompensation.
Liver Diseases
Real time PCR detection of the PI*Z and PI*S mutations associated with alpha-1 antitrypsin deficiency.
Liver Diseases
Role of alpha-1-antichymotrypsin deficiency in promoting cirrhosis in two siblings with heterozygous alpha-1-antitrypsin deficiency phenotype SZ.
Liver Diseases
Screening of alpha-1-antitrypsin gene by denaturing gradient gel electrophoresis (DGGE).
Liver Diseases
Serine peptidase inhibitor Kazal type III (SPINK3) promotes BRL-3A cell proliferation by targeting the PI3K-AKT signaling pathway.
Liver Diseases
SerpinB3 Promotes Pro-fibrogenic Responses in Activated Hepatic Stellate Cells.
Liver Diseases
Serum protease inhibitors in opisthorchiasis, hepatoma, cholangiocarcinoma, and other liver diseases.
Liver Diseases
Ubiquitin-specific protease 22 ameliorates chronic alcohol-associated liver disease by regulating BRD4.
Liver Diseases
Ubiquitin-specific protease 4 is an endogenous negative regulator of metabolic dysfunctions in nonalcoholic fatty liver disease.
Liver Diseases
[Alpha 1-antitrypsin deficiency: a review with special reference to the significance of heterozygous deficiency]
Liver Diseases
[Molecular diagnostics of alpha-1-antitrypsine deficiency in clinical practice.]
Liver Diseases, Alcoholic
Complements are involved in alcoholic fatty liver disease, hepatitis and fibrosis.
Liver Failure
Effects of Antiretroviral Molecules on Survival and Gene Expression of an Osteoblast-like Cell Line.
Liver Failure
Intracranial hemorrhage and liver-associated deaths associated with tipranavir/ritonavir: review of cases from the FDA's Adverse Event Reporting System.
Liver Failure
Levels of von Willebrand factor antigen and von Willebrand factor cleaving protease (ADAMTS13) activity predict clinical events in chronic heart failure.
Liver Failure, Acute
An unbalance between von Willebrand factor and ADAMTS13 in acute liver failure: Implications for hemostasis and clinical outcome.
Liver Failure, Acute
Evidence for the presence of an inactive precursor of human hepatocyte growth factor in plasma and sera of patients with liver diseases.
Liver Failure, Acute
Gabexate mesilate, a synthetic protease inhibitor, attenuates carbon tetrachloride-induced liver injury in rats.
Liver Failure, Acute
Prognostic factors for fatal outcomes prior to receiving liver transplantation in patients with non-acetaminophen-related fulminant hepatic failure.
Liver Failure, Acute
Secretory leukocyte protease inhibitor: A pivotal mediator of anti-inflammatory responses in acetaminophen-induced acute liver failure.
Liver Neoplasms
Aprotinin inhibits local platelet trapping and improves tissue destruction in hepatic cryosurgery.
Liver Neoplasms
Hepatitis B Virus X Protein-Induced Serine Protease Inhibitor Kazal Type 1 Is Associated with the Progression of HBV-Related Diseases.
Liver Neoplasms
High expression levels of IKKalpha and IKKbeta are necessary for the malignant properties of liver cancer.
Liver Neoplasms
Intact stable isotope labeled plasma proteins from the SILAC-labeled HepG2 secretome.
Liver Neoplasms
Liver cancer protease activity profiles support therapeutic options with matrix metalloproteinase-activatable oncolytic measles virus.
Liver Neoplasms
miR-328-3p overexpression attenuates the malignant proliferation and invasion of liver cancer via targeting Endoplasmic Reticulum Metallo Protease 1 to inhibit AKT phosphorylation.
Liver Neoplasms
SERPINB3 protects from oxidative damage by chemotherapeutics through inhibition of mitochondrial respiratory complex I.
Liver Neoplasms
SPRTN protease and checkpoint kinase 1 cross-activation loop safeguards DNA replication.
Liver Neoplasms, Experimental
Activity of chromatin-bound protease in histone fractions from rat liver and Morris hepatoma.
Liver Neoplasms, Experimental
High molecular mass phosphoproteins in the rat liver nuclear matrix identification of a prominent 110,000 Dalton species.
Liver Neoplasms, Experimental
Purification, characterization and localization of serine protease of Morris hepatoma 8999.
Lung Diseases
4-Oxo-beta-lactams (azetidine-2,4-diones) are potent and selective inhibitors of human leukocyte elastase.
Lung Diseases
?1-antitrypsin Deficiency: A Misfolded Secretory Protein Variant with Unique Effects on the Endoplasmic Reticulum.
Lung Diseases
A functional variant of elafin with improved anti-inflammatory activity for pulmonary inflammation.
Lung Diseases
A novel proteolytic cascade generates an extracellular matrix-derived chemoattractant in chronic neutrophilic inflammation.
Lung Diseases
A protease-activated pathway underlying Th cell type 2 activation and allergic lung disease.
Lung Diseases
A specialized method of sputum collection and processing for therapeutic interventions in cystic fibrosis.
Lung Diseases
Aerosol treatment with MNEI suppresses bacterial proliferation in a model of chronic Pseudomonas aeruginosa lung infection.
Lung Diseases
Airway proteins involved in bacterial clearance susceptible to cathepsin G proteolysis.
Lung Diseases
Bioengineering of an elastase inhibitor from Caesalpinia echinata (Brazil wood) seeds.
Lung Diseases
C/EBP? Regulates the Protease/Anti-protease Balance Required for Bronchiolar Epithelium Regeneration.
Lung Diseases
Carrageenan inhibits granzyme A-induced detachment of and interleukin-8 release from alveolar epithelial A549 cells.
Lung Diseases
Characterisation of urokinase plasminogen activator receptor variants in human airway and peripheral cells.
Lung Diseases
Clinical significance of serum levels of secretory leukocyte protease inhibitor in patients with systemic sclerosis.
Lung Diseases
COPD and endobronchial polyposis associated with hypogammaglobulinemia. Are proteolytic enzymes involved?
Lung Diseases
Differential susceptibility of Dectin-1 isoforms to functional inactivation by neutrophil and fungal proteases.
Lung Diseases
Fibrin/fibrinogen in lungs and respiratory secretions of horses with chronic pulmonary disease.
Lung Diseases
Health implications of alpha1-antitrypsin deficiency in Sub-Sahara African countries and their emigrants in Europe and the New World.
Lung Diseases
Human Neutrophil Elastase-Mediated Cleavage Sites of MMP-9 and TIMP-1: Implications to Cystic Fibrosis Proteolytic Dysfunction.
Lung Diseases
Influenza virus infection increases ACE2 expression and shedding in human small airway epithelial cells.
Lung Diseases
Inhibition of human leukocyte elastase. 4. Selection of a substituted cephalosporin (L-658,758) as a topical aerosol.
Lung Diseases
Lard-based high-fat diet increases secretory leukocyte protease inhibitor expression and attenuates the inflammatory response of acute lung injury in endotoxemic rats.
Lung Diseases
Modulation of cytokine production and silica-induced lung fibrosis by inhibitors of aminopeptidase N and of dipeptidyl peptidase-IV-related proteases.
Lung Diseases
N-Arylacyl O-sulfonated aminoglycosides as novel inhibitors of human neutrophil elastase, cathepsin G and proteinase 3.
Lung Diseases
Neutrophil elastase and matrix metalloproteinase 12 in cystic fibrosis lung disease.
Lung Diseases
Neutrophil Extracellular Traps in Pulmonary Diseases: Too Much of a Good Thing?
Lung Diseases
Optimization of total protein and activity assays for the detection of MMP-12 in induced human sputum.
Lung Diseases
Patterns of neutrophil serine protease-dependent cleavage of surfactant protein D in inflammatory lung disease.
Lung Diseases
Phagocyte enzymes in bronchoalveolar lavage from patients with pulmonary sarcoidosis and collagen vascular disorders.
Lung Diseases
Protease inhibitor phenotypes and pulmonary disease in patients with Sjögren's syndrome.
Lung Diseases
Proteases and antiproteases in chronic neutrophilic lung disease - relevance to drug discovery.
Lung Diseases
Protection of alpha-1 protease inhibitor by plasma antioxidants. Potential abnormality in chronic obstructive pulmonary disease (COPD).
Lung Diseases
Pulmonary deposition and disappearance of aerosolised secretory leucocyte protease inhibitor.
Lung Diseases
Repetitive Intradermal Bleomycin Injections Evokes T Helper Cell 2 Cytokine-driven Pulmonary Fibrosis.
Lung Diseases
Respiratory failure associated with the lipodystrophy syndrome in an HIV-positive patient with compromised lung function.
Lung Diseases
Secretory leucocyte protease inhibitor inhibits interferon-gamma-induced cathepsin S expression.
Lung Diseases
The Diagnostic Value of Alpha-1-Antitrypsin Phenotype in Patients with Granulomatosis with Polyangiitis.
Lung Diseases
The Importance of N186 in the Alpha-1-Antitrypsin Shutter Region Is Revealed by the Novel Bologna Deficiency Variant.
Lung Diseases
The Pseudomonas aeruginosa secretory product pyocyanin inactivates alpha1 protease inhibitor: implications for the pathogenesis of cystic fibrosis lung disease.
Lung Diseases
The Serpin Superfamily and Their Role in the Regulation and Dysfunction of Serine Protease Activity in COPD and Other Chronic Lung Diseases.
Lung Diseases
Transferrin and lactoferrin undergo proteolytic cleavage in the Pseudomonas aeruginosa-infected lungs of patients with cystic fibrosis.
Lung Diseases
[Changes in protease inhibitor balance of the bronchoalveolar secretion in children with inflammatory lung diseases]
Lung Diseases
[Dynamic changes in polymorphonuclear cell elastase-alpha 1 protease inhibitor complex, a stress marker, in various pulmonary diseases]
Lung Diseases
[Etiologic significance of hereditary deficiency of proteinase alpha1-inhibitor in the formation of respiratory diseases]
Lung Diseases
[Inhibitory effects of alpha 1 protease inhibitor on the production of IL-1 and TNF alpha by alveolar macrophages in patients with lung cancer]
Lung Diseases
[Protease activity and the level of antibodies to connective tissue elements in various lung diseases]
Lung Diseases
[Pulmonary veno-arterial alpha 1 protease inhibitor differences in patients with chronic lung disease]
Lung Diseases
[Status of the protease inhibitor system in patients with dust-induced lung diseases]
Lung Diseases
[Studies on the classification of thermophilic actinomycetes. IV. Determination of thermophilic Streptomyces hygroscopicus group]
Lung Diseases
[The mechanisms of the development of respiratory tract ciliary dysfunction in nonspecific lung diseases]
Lung Diseases
[The protease inhibitor system in children (in diseases of the lung, liver and hereditary alpha 1-antitrypsin deficiency)]
Lung Diseases, Fungal
Immunologic significance of a collagen-derived culture filtrate containing proteolytic activity in Aspergillus-related diseases.
Lung Diseases, Interstitial
Interstitial Lung Disease as an Adverse Drug Reaction in Japan: Exploration of Regulatory Actions as a Basis for High Reporting.
Lung Diseases, Obstructive
Loss of skin elasticity is associated with pulmonary emphysema, biomarkers of inflammation, and matrix metalloproteinase activity in smokers.
Lung Diseases, Obstructive
Patterns of forced expiratory flows in groups at risk for chronic obstructive pulmonary disease.
Lung Diseases, Obstructive
Pharmacological and genetic reappraisals of protease and oxidative stress pathways in a mouse model of obstructive lung diseases.
Lung Diseases, Obstructive
Protection of alpha-1 protease inhibitor by plasma antioxidants. Potential abnormality in chronic obstructive pulmonary disease (COPD).
Lung Diseases, Obstructive
Relation of protease inhibitor phenotypes to obstructive lung diseases in a community.
Lung Diseases, Obstructive
The impacts of parity on spirometric parameters: a systematic review.
Lung Diseases, Obstructive
[Etiologic significance of hereditary deficiency of proteinase alpha1-inhibitor in the formation of respiratory diseases]
Lung Injury
A randomized, placebo-controlled trial of aprotinin to reduce primary graft dysfunction following lung transplantation.
Lung Injury
Activation of rat alveolar macrophage-derived latent transforming growth factor beta-1 by plasmin requires interaction with thrombospondin-1 and its cell surface receptor, CD36.
Lung Injury
Alpha-1-antichymotrypsin is an effective inhibitor of pancreatitis-induced lung injury.
Lung Injury
Alterations of alveolar macrophage function and level of bronchopulmonary protease inhibitors in O,O,S-trimethyl phosphorothioate-induced lung injury.
Lung Injury
Annexin A2 contributes to lung injury and fibrosis by augmenting factor Xa fibrogenic activity.
Lung Injury
Antithrombin III attenuates pulmonary tissue injury caused by mesenteric ischemia-reperfusion.
Lung Injury
Aprotinin attenuated ischemia-reperfusion injury in an isolated rat lung model after 18-hours preservation.
Lung Injury
Drug-induced lung injury associated with combination therapy of daclatasvir and asunaprevir: The first case report.
Lung Injury
Effect of hirudin on the levels of acute lung injury rat tumor necrosis factor-? and matrix metalloproteinase-12.
Lung Injury
Effects of a synthetic protease inhibitor (gabexate mesilate) and a neutrophil elastase inhibitor (sivelestat sodium) on acid-induced lung injury in rats.
Lung Injury
Effects of free radical scavengers, methylprednisolone, and ulinastatin on acute xanthine and xanthine oxidase-induced lung injury in rats.
Lung Injury
Effects of lung injury on pulmonary surfactant aggregate conversion in vivo and in vitro.
Lung Injury
Evaluation of protease inhibitors and an antioxidant for treatment of sulfur mustard-induced toxic lung injury.
Lung Injury
Evidence of increased matrix metalloproteinase-9 concentration in patients following cardiopulmonary bypass.
Lung Injury
Hematopoietic protease nexin-1 protects against lung injury by preventing thrombin signaling in mice.
Lung Injury
Inhibition of human neutrophil elastase by polyguanylic acid and other synthetic RNA homopolymers.
Lung Injury
Oxidative and Proteolytic Inactivation of Alpha-1 Antitrypsin in Bronchopulmonary Dysplasia Pathogenesis: A Top-Down Proteomic Bronchoalveolar Lavage Fluid Analysis.
Lung Injury
Protein kinase C modulates the pulmonary inflammatory response in acute pancreatitis.
Lung Injury
Regulatory effects of endogenous protease inhibitors in acute lung inflammatory injury.
Lung Injury
Secretory leukocyte protease inhibitor gene deletion alters bleomycin-induced lung injury, but not development of pulmonary fibrosis.
Lung Injury
Small volume resuscitation with hypertonic saline is more effective in ameliorating trauma-hemorrhagic shock-induced lung injury, neutrophil activation and red blood cell dysfunction than pancreatitic protease inhibition.
Lung Injury
The role of proteases in 4-ipomeanol-induced enhancement of Sendai viral pneumonia in mice.
Lung Injury
Tracheobronchial protease inhibitors, body surface area burns, and mortality in smoke inhalation.
Lung Injury
Transferrin and lactoferrin undergo proteolytic cleavage in the Pseudomonas aeruginosa-infected lungs of patients with cystic fibrosis.
Lung Injury
Transmembrane protease, serine 4 (TMPRSS4) is upregulated in IPF lungs and increases the fibrotic response in bleomycin-induced lung injury.
Lung Injury
Trypsin and activation of circulating trypsinogen contribute to pancreatitis-associated lung injury.
Lung Injury
[Effects of high frequency oscillatory ventilation and its combination with pulmonary surfactant treatment on inflammatory response in rabbit lung with inhalation injury]
Lung Injury
[Experimental study on effect and mechanism of soybean protease inhibitor on endotoxin-induced acute lung injury]
Lung Neoplasms
A Purified Serine Protease from Nereis virens and Its Impaction of Apoptosis on Human Lung Cancer Cells.
Lung Neoplasms
Activity-based Near-Infrared Fluorogenic Probe Enables In Vitro and In Vivo Profiling of Neutrophil Elastase.
Lung Neoplasms
ADAM10 overexpression in human non-small cell lung cancer correlates with cell migration and invasion through the activation of the Notch1 signaling pathway.
Lung Neoplasms
Analysis of host- and tumor-derived proteinases using a custom dual species microarray reveals a protective role for stromal matrix metalloproteinase-12 in non-small cell lung cancer.
Lung Neoplasms
Anti-cancer activity of the novel 2-hydroxydiarylamide derivatives IMD-0354 and KRT1853 through suppression of cancer cell invasion, proliferation, and survival mediated by TMPRSS4.
Lung Neoplasms
Clinical and prognostic importance of XIAP and USP8 in advanced stages of non-small cell lung cancer.
Lung Neoplasms
Clinical significance of serum protease activated receptor1 levels in patients with lung cancer.
Lung Neoplasms
Clinical significance of the p53 pathway and associated gene therapy in non-small cell lung cancers.
Lung Neoplasms
Degradation of tenascin-C and activity of matrix metalloproteinase-2 are associated with tumor recurrence in early stage non-small cell lung cancer.
Lung Neoplasms
Deubiquitinase USP9X promotes cell migration, invasion and inhibits apoptosis of human pancreatic cancer.
Lung Neoplasms
Differential regulation of protease and extracellular matrix protein expression by transforming growth factor-beta 1 in non-small cell lung cancer cells and normal human bronchial epithelial cells.
Lung Neoplasms
Enhancement of Apo2L/TRAIL (tumor necrosis factor-related apoptosis-inducing ligand)-induced apoptosis in non-small cell lung cancer cell lines by chemotherapeutic agents without correlation to the expression level of cellular protease caspase-8 inhibitory protein.
Lung Neoplasms
Epicatechin-3-gallate reverses TGF-?1-induced epithelial-to-mesenchymal transition and inhibits cell invasion and protease activities in human lung cancer cells.
Lung Neoplasms
Epigenetic Silencing of Ubiquitin Specific Protease 4 by Snail1 Contributes to Macrophage-Dependent Inflammation and Therapeutic Resistance in Lung Cancer.
Lung Neoplasms
Gene expression profile of A549 cells from tissue of 4D model predicts poor prognosis in lung cancer patients.
Lung Neoplasms
Global Decrease of Histone H3K27 Acetylation in ZEB1-Induced Epithelial to Mesenchymal Transition in Lung Cancer Cells.
Lung Neoplasms
HABP2 is a Novel Regulator of Hyaluronan-Mediated Human Lung Cancer Progression.
Lung Neoplasms
HAI-2 as a novel inhibitor of plasmin represses lung cancer cell invasion and metastasis.
Lung Neoplasms
High Expression of Ubiquitin-Specific Protease 8 (USP8) Is Associated with Poor Prognosis in Patients with Cervical Squamous Cell Carcinoma.
Lung Neoplasms
High frequency of coexpression of maspin with p63 and p53 in squamous cell carcinoma but not in adenocarcinoma of the lung.
Lung Neoplasms
High temperature requirement A3 (HtrA3) promotes etoposide- and cisplatin-induced cytotoxicity in lung cancer cell lines.
Lung Neoplasms
Human Neutrophil Elastase Activated Fluorescent Probe for Pulmonary Diseases Based on Fluorescence Resonance Energy Transfer Using CdSe/ZnS Quantum Dots.
Lung Neoplasms
Hypoxia-inducible factor-1 alpha in non small cell lung cancer: relation to growth factor, protease and apoptosis pathways.
Lung Neoplasms
Increased plasma levels of serine proteinase inhibitors in lung cancer patients.
Lung Neoplasms
Influence of MMP-2 and MMP-9 promoter polymorphisms on gene expression and clinical outcome of non-small cell lung cancer.
Lung Neoplasms
Inhibition of USP14 induces ER stress-mediated autophagy without apoptosis in lung cancer cell line A549.
Lung Neoplasms
Jizanpeptins, Cyanobacterial Protease Inhibitors from a Symploca sp. Cyanobacterium Collected in the Red Sea.
Lung Neoplasms
Knockdown of ubiquitin?specific protease 51 attenuates cisplatin resistance in lung cancer through ubiquitination of zinc?finger E?box binding homeobox 1.
Lung Neoplasms
Lack of association between the unique LMP2 gene polymorphism and the outcome of lung cancer in a population of Chinese Han nationality.
Lung Neoplasms
Matrix-metalloprotease resistant mucin-16 (MUC16) peptide mutants represent a worse lung adenocarcinoma outcome.
Lung Neoplasms
Methylation-induced downregulation of TFPI-2 causes TMPRSS4 overexpression and contributes to oncogenesis in a subset of non-small-cell lung carcinoma.
Lung Neoplasms
Modification of beta-2-microglobulin in sera from patients with small cell lung cancer: evidence for involvement of a serine protease.
Lung Neoplasms
Nafamostat mesilate, a serine protease inhibitor, suppresses interferon-gamma-induced up-regulation of programmed cell death ligand 1 in human cancer cells.
Lung Neoplasms
Near infrared thoracoscopy of tumoral protease activity for improved detection of peripheral lung cancer.
Lung Neoplasms
Nuclear localization of apoptosis protease activating factor-1 predicts survival after tumor resection in early-stage non-small cell lung cancer.
Lung Neoplasms
Obtusilactone A and (-)-sesamin induce apoptosis in human lung cancer cells by inhibiting mitochondrial Lon protease and activating DNA damage checkpoints.
Lung Neoplasms
Osteopontin increases lung cancer cells migration via activation of the alphavbeta3 integrin/FAK/Akt and NF-kappaB-dependent pathway.
Lung Neoplasms
Overexpression of TMPRSS4 in non-small cell lung cancer is associated with poor prognosis in patients with squamous histology.
Lung Neoplasms
Overexpression of ubiquitin-specific protease 22 predicts poor survival in patients with early-stage non-small cell lung cancer.
Lung Neoplasms
Plant-derived protease inhibitors LC-pi (Lavatera cashmeriana) inhibit human lung cancer cell proliferation in vitro.
Lung Neoplasms
Plasminogen Activator Inhibitor-2 Plays a Leading Prognostic Role among Protease Families in Non-Small Cell Lung Cancer.
Lung Neoplasms
Potential importance of protease activated receptor (PAR)-1 expression in the tumor stroma of non-small-cell lung cancer.
Lung Neoplasms
Prognostic relevance of TTF-1 and MMP-9 expression in advanced lung adenocarcinoma.
Lung Neoplasms
Protease inhibitors exposure is not related to lung cancer risk in HIV smoker patients: a nested case-control study.
Lung Neoplasms
Protease inhibitors suppress in vitro growth of human small cell lung cancer.
Lung Neoplasms
Protease Serine S1 Family Member 8 (PRSS8) Inhibits Tumor Growth In Vitro and In Vivo in Human Non-Small Cell Lung Cancer.
Lung Neoplasms
Protein Z/protein Z-dependent protease inhibitor system in human non-small-cell lung cancer tissue.
Lung Neoplasms
Pulsed Low-Frequency Magnetic Fields Induce Tumor Membrane Disruption and Altered Cell Viability.
Lung Neoplasms
Rubus idaeus L. reverses epithelial-to-mesenchymal transition and suppresses cell invasion and protease activities by targeting ERK1/2 and FAK pathways in human lung cancer cells.
Lung Neoplasms
Screening of alpha-1-antitrypsin gene by denaturing gradient gel electrophoresis (DGGE).
Lung Neoplasms
Serine Protease from Nereis virens Inhibits H1299 Lung Cancer Cell Proliferation via the PI3K/AKT/mTOR Pathway.
Lung Neoplasms
Single cell multiplexed assay for proteolytic activity using droplet microfluidics.
Lung Neoplasms
Skeletal muscle mRNA levels for cathepsin B, but not components of the ubiquitin-proteasome pathway, are increased in patients with lung cancer referred for thoracotomy.
Lung Neoplasms
Sodium hydrogen exchanger and phospholipase D are required for alpha1-adrenergic receptor stimulation of metalloproteinase-9 and cellular invasion in CCL39 fibroblasts.
Lung Neoplasms
Symplocamide A, a potent cytotoxin and chymotrypsin inhibitor from the marine Cyanobacterium Symploca sp.
Lung Neoplasms
Targeted gene therapy of the HSV-TK/hIL-12 fusion gene controlled by the hSLPI gene promoter of human non-small cell lung cancer in vitro.
Lung Neoplasms
Targeting the cellular schizophrenia. Likely employment of the antipsychotic agent pimozide in treatment of refractory cancers and glioblastoma.
Lung Neoplasms
Testes-specific protease 50 as an independent risk factor for poor prognosis in patients with non-small cell lung cancer.
Lung Neoplasms
The HtrA3 protease promotes drug-induced death of lung cancer cells by cleavage of the X-linked inhibitor of apoptosis protein (XIAP).
Lung Neoplasms
The roles of MASPIN expression and subcellular localization in non-small cell lung cancer.
Lung Neoplasms
TMPRSS4 regulates levels of integrin ?5 in NSCLC through miR-205 activity to promote metastasis.
Lung Neoplasms
Transmembrane Protease TMPRSS11B Promotes Lung Cancer Growth by Enhancing Lactate Export and Glycolytic Metabolism.
Lung Neoplasms
Tumor suppressive microRNA-124a inhibits stemness and enhances gefitinib sensitivity of non-small cell lung cancer cells by targeting ubiquitin-specific protease 14.
Lung Neoplasms
Tumor transcriptome reveals the predictive and prognostic impact of lysosomal protease inhibitors in non-small-cell lung cancer.
Lung Neoplasms
Ubiquitin-specific protease 22 is critical to in vivo angiogenesis, growth and metastasis of non-small cell lung cancer.
Lung Neoplasms
Ubiquitin-specific protease 39 is overexpressed in human lung cancer and promotes tumor cell proliferation in vitro.
Lung Neoplasms
Up-regulation of urokinase-type plasminogen activator expression by the HER2/neu proto-oncogene.
Lung Neoplasms
Urinary detection of lung cancer in mice via noninvasive pulmonary protease profiling.
Lung Neoplasms
[Changes in serum protease and cytokine in patients with silicosis, tuberculosis, and lung cancer].
Lung Neoplasms
[Expression of USP9X in Non-small Cell Lung Cancer and Its Clinical Significance].
Lung Neoplasms
[Inhibitory effects of alpha 1 protease inhibitor on the production of IL-1 and TNF alpha by alveolar macrophages in patients with lung cancer]
Lung Neoplasms
[Screening the Drug Sensitivity Genes Related to GEM and CDDP in the Lung Cancer Cell-lines.]
Lupus Erythematosus, Systemic
C4a anaphylatoxin levels as an indicator of disease activity in systemic lupus erythematosus.
Lupus Erythematosus, Systemic
Failure to detect type-C virus p30-related antigen in systemic lupus erythematosus: false-positive reaction due to protease activity.
Lupus Erythematosus, Systemic
Proteolytic inactivation of nuclear alarmin high-mobility group box 1 by complement protease C1s during apoptosis.
Lupus Erythematosus, Systemic
Urinary insulin-like growth factors (IGF) and IGF-binding proteins in normal subjects, growth hormone deficiency, and renal disease.
Lupus Erythematosus, Systemic
Von Willebrand factor cleaving protease (ADAMTS-13) in 123 patients with connective tissue diseases (systemic lupus erythematosus and systemic sclerosis).
Lupus Nephritis
Effect of FUT-175, a new synthetic protease inhibitor, on the development of lupus nephritis in (NZB x NZW) F1 mice.
Lupus Nephritis
Immunohistochemical detection of immunoglobulins and complements in formaldehyde-fixed and paraffin-embedded renal biopsy tissues; an adjunct for diagnosis of glomerulonephritis.
Lupus Nephritis
Increased mRNA expression encoding for medullasin in peripheral blood mononuclear cells from patients with IgA nephropathy.
Lupus Nephritis
Urine proteome scans uncover total urinary protease, prostaglandin D synthase, serum amyloid P, and superoxide dismutase as potential markers of lupus nephritis.
Lyme Disease
Borrelia burgdorferi?BbHtrA degrades host ECM proteins and stimulates release of inflammatory cytokines in vitro.
Lyme Disease
Evaluation of Borrelia burgdorferi BbHtrA Protease as a Vaccine Candidate for Lyme Borreliosis in Mice.
Lyme Disease
HtrA, a Temperature- and Stationary Phase-Activated Protease Involved in Maturation of a Key Microbial Virulence Determinant, Facilitates Borrelia burgdorferi Infection in Mammalian Hosts.
Lyme Disease
Lyme disease spirochaetes possess an aggrecan-binding protease with aggrecanase activity.
Lyme Disease
The bacterial nucleoid visualized by fluorescence microscopy of cells lysed within agarose: comparison of Escherichia coli and spirochetes of the genus Borrelia.
Lymphangioleiomyomatosis
Cathepsin K in Lymphangioleiomyomatosis: LAM Cell-Fibroblast Interactions Enhance Protease Activity by Extracellular Acidification.
Lymphatic Metastasis
'Increased expression of seprase, a membrane-type serine protease, is associated with lymph node metastasis in human colorectal cancer'.
Lymphatic Metastasis
Increased expression of seprase, a membrane-type serine protease, is associated with lymph node metastasis in human colorectal cancer.
Lymphatic Metastasis
Predictive value of cathepsin-D for cervical lymph node metastasis in head and neck squamous cell carcinoma.
Lymphatic Metastasis
Role of protease activated receptor-2 in lymph node metastasis of uterine cervical cancers.
Lymphatic Metastasis
The HtrA1 serine protease is down-regulated during human melanoma progression and represses growth of metastatic melanoma cells.
Lymphatic Metastasis
Ubiquitin-specific protease 14 expression in colorectal cancer is associated with liver and lymph node metastases.
Lymphoma
A herpesvirus ubiquitin-specific protease is critical for efficient T cell lymphoma formation.
Lymphoma
A multivalent DNA aptamer specific for the B-cell receptor on human lymphoma and leukemia.
Lymphoma
A role for MALT1 activity in Kaposi's sarcoma-associated herpes virus latency and growth of primary effusion lymphoma.
Lymphoma
Aberrant localization of apoptosis protease activating factor-1 in lipid raft sub-domains of diffuse large B cell lymphomas.
Lymphoma
Activation of cellular death programs associated with immunosenescence-like phenotype in TPPII knockout mice.
Lymphoma
Activity-based probes for detection of active MALT1 paracaspase in immune cells and lymphomas.
Lymphoma
Antiapoptotic properties of MALT1 protease are associated with redox homeostasis in ABC-DLBCL cells.
Lymphoma
Bax-alpha promotes apoptosis induced by cancer chemotherapy and accelerates the activation of caspase 3-like cysteine proteases in p53 double mutant B lymphoma Namalwa cells.
Lymphoma
Calotropin regulates the apoptosis of non?small cell cancer by regulating the cytotoxic T?lymphocyte associated antigen 4?mediated TGF??/ERK signaling pathway.
Lymphoma
cDNA clones from autocrine thymic lymphoma cells encode two mitogenic proteins, a serine protease and a truncated T-cell receptor beta-chain.
Lymphoma
Characterization of soluble CD44 in the circulation of mice. Levels are affected by immune activity and tumor growth.
Lymphoma
Cytoprotective effects of myristicin against hypoxia?induced apoptosis and endoplasmic reticulum stress in rat dorsal root ganglion neurons.
Lymphoma
Differential sensitivity of anti-IgM-induced and NaF-induced inositol phospholipid metabolism to serine protease inhibitors in BAL17 B lymphoma cells.
Lymphoma
Evidence for a guanine nucleotide-binding regulatory protein in invertebrate and mammalian sperm. Identification by islet-activating protein-catalyzed ADP-ribosylation and immunochemical methods.
Lymphoma
Expression and clinical significance of ubiquitin?specific?processing protease 34 in diffuse large B?cell lymphoma.
Lymphoma
Expression and utilization of chymotrypsin-like but not trypsin-like serine protease enzymes by nonspecific T killer cells activated by anti-CD3 monoclonal antibody.
Lymphoma
Expression of the granzyme B inhibitor PI9 predicts outcome in nasal NK/T-cell lymphoma: results of a Western series of 48 patients treated with first-line polychemotherapy within the Groupe d'Etude des Lymphomes de l'Adulte (GELA) trials.
Lymphoma
GLS1-mediated glutaminolysis unbridled by MALT1 protease promotes psoriasis pathogenesis.
Lymphoma
Heparanase activity expressed by platelets, neutrophils, and lymphoma cells releases active fibroblast growth factor from extracellular matrix.
Lymphoma
Icariin protects against ischemia?reperfusion injury in H9C2 cells by upregulating heat shock protein 20.
Lymphoma
Identification of Novel Fused Heteroaromatics-Based MALT1 Inhibitors by High-Throughput Screening to Treat B Cell Lymphoma.
Lymphoma
Immunolocalization of the ICE/Ced-3-family protease, CPP32 (Caspase-3), in non-Hodgkin's lymphomas, chronic lymphocytic leukemias, and reactive lymph nodes.
Lymphoma
Inhibition of MALT1 protease activity is selectively toxic for activated B cell-like diffuse large B cell lymphoma cells.
Lymphoma
Inhibitory effect of hyperoside isolated from Zanthoxylum bungeanum leaves on SW620 human colorectal cancer cells via induction of the p53 signaling pathway and apoptosis.
Lymphoma
Licochalcone A induces T24 bladder cancer cell apoptosis by increasing intracellular calcium levels.
Lymphoma
Luteolin induces myelodysplastic syndrome?derived cell apoptosis via the p53?dependent mitochondrial signaling pathway mediated by reactive oxygen species.
Lymphoma
MALT1 as a promising target to treat lymphoma and other diseases related to MALT1 anomalies.
Lymphoma
MALT1 inhibitors prevent the development of DSS-induced experimental colitis in mice via inhibiting NF-?B and NLRP3 inflammasome activation.
Lymphoma
MALT1 Protease Activity Controls the Expression of Inflammatory Genes in Keratinocytes upon Zymosan Stimulation.
Lymphoma
Prognostic significance of activated cytotoxic T-lymphocytes in primary nodal diffuse large B-cell lymphomas.
Lymphoma
Protease inhibitors restore radiation-induced apoptosis to Bcl-2-expressing lymphoma cells.
Lymphoma
Protease nexin-1 prevents growth of human B cell lymphoma via inhibition of sonic hedgehog signaling.
Lymphoma
Protease receptors in Hodgkin's disease: expression of the factor Xa receptor, effector cell protease receptor-1, in Reed-Sternberg cells.
Lymphoma
Recombinant Pierisin-5 Induces Apoptosis and Differential Expression of Bcl-2, Bax, and p53 in Human Cancer Cells.
Lymphoma
Saquinavir enhances the mucosal toxicity of infusional cyclophosphamide, doxorubicin, and etoposide in patients with HIV-associated non-Hodgkin's lymphoma.
Lymphoma
Small Molecule Inhibition of the Ubiquitin-specific Protease USP2 Accelerates cyclin D1 Degradation and Leads to Cell Cycle Arrest in Colorectal Cancer and Mantle Cell Lymphoma Models.
Lymphoma
Structure elucidation and absolute configuration of metabolites from the soil-derived fungus Dictyosporium digitatum using spectroscopic and computational methods.
Lymphoma
Superior Therapeutic Index in Lymphoma Therapy: CD30(+) CD34(+) Hematopoietic Stem Cells Resist a Chimeric Antigen Receptor T-cell Attack.
Lymphoma
Survival in HIV-infected patients with lymphoma according to the choice of antiretroviral treatment: an observational multicentre study.
Lymphoma
The ability of Ia and H-2Kk-bearing membranes to replace the antigen-presenting cell in an H-2Kk allogeneic cytotoxic T cell response.
Lymphoma
The mitochondrial ATP-dependent Lon protease: a novel target in lymphoma death mediated by the synthetic triterpenoid CDDO and its derivatives.
Lymphoma
The protease activity of the paracaspase MALT1 is controlled by monoubiquitination.
Lymphoma, AIDS-Related
Improved prognosis in patients with acquired immunodeficiency syndrome-related lymphoma.
Lymphoma, AIDS-Related
Risk factors for febrile neutropenia during chemotherapy for HIV-related lymphoma.
Lymphoma, B-Cell
Activity-based probes for detection of active MALT1 paracaspase in immune cells and lymphomas.
Lymphoma, B-Cell
Acute Noise Exposure Is Associated With Intrinsic Apoptosis in Murine Central Auditory Pathway.
Lymphoma, B-Cell
Antiapoptotic properties of MALT1 protease are associated with redox homeostasis in ABC-DLBCL cells.
Lymphoma, B-Cell
Azaphenylalanine-based serine protease inhibitors induce caspase-mediated apoptosis.
Lymphoma, B-Cell
Deficiency of dietary pyridoxine disturbed the intestinal physical barrier function of young grass carp (Ctenopharyngodon idella).
Lymphoma, B-Cell
Dietary protein levels regulated antibacterial activity, inflammatory response and structural integrity in the head kidney, spleen and skin of grass carp (Ctenopharyngodon idella) after challenged with Aeromonas hydrophila.
Lymphoma, B-Cell
Dietary vitamin C deficiency depressed the gill physical barriers and immune barriers referring to Nrf2, apoptosis, MLCK, NF-?B and TOR signaling in grass carp (Ctenopharyngodon idella) under infection of Flavobacterium columnare.
Lymphoma, B-Cell
Dietary vitamin C deficiency depresses the growth, head kidney and spleen immunity and structural integrity by regulating NF-?B, TOR, Nrf2, apoptosis and MLCK signaling in young grass carp (Ctenopharyngodon idella).
Lymphoma, B-Cell
Effect of dietary phosphorus deficiency on the growth, immune function and structural integrity of head kidney, spleen and skin in young grass carp (Ctenopharyngodon idella).
Lymphoma, B-Cell
Effects of dietary protein levels on the disease resistance, immune function and physical barrier function in the gill of grass carp (Ctenopharyngodon idella) after challenged with Flavobacterium columnare.
Lymphoma, B-Cell
Essential role of MALT1 protease activity in activated B cell-like diffuse large B-cell lymphoma.
Lymphoma, B-Cell
Expression of p16 in lymph node metastases of adjuvantly treated stage III colorectal cancer patients identifies poor prognostic subgroups: a retrospective analysis of biomarkers in matched primary tumor and lymph node metastases.
Lymphoma, B-Cell
Fatty Acids of CLA-enriched Egg Yolks Can Induce Mitochondrial Pathway of Apoptosis in MCF-7 Breast Cancer Cells.
Lymphoma, B-Cell
Identification of collaborative activities with oxidative phosphorylation in bipolar disorder.
Lymphoma, B-Cell
Identification of Novel Fused Heteroaromatics-Based MALT1 Inhibitors by High-Throughput Screening to Treat B Cell Lymphoma.
Lymphoma, B-Cell
Induction of apoptosis in HCT-116 colon cancer cells by polysaccharide of Larimichthys crocea swim bladder.
Lymphoma, B-Cell
Influences of cold atmospheric plasma on apoptosis related molecules in osteoblast-like cells in vitro.
Lymphoma, B-Cell
Inhibition of MALT1 protease activity is selectively toxic for activated B cell-like diffuse large B cell lymphoma cells.
Lymphoma, B-Cell
MALT1 inhibitors prevent the development of DSS-induced experimental colitis in mice via inhibiting NF-?B and NLRP3 inflammasome activation.
Lymphoma, B-Cell
Malt1 protease inactivation efficiently dampens immune responses but causes spontaneous autoimmunity.
Lymphoma, B-Cell
Monoubiquitination and Activity of the Paracaspase MALT1 Requires Glutamate 549 in the Dimerization Interface.
Lymphoma, B-Cell
Optimal dietary protein level improved growth, disease resistance, intestinal immune and physical barrier function of young grass carp (Ctenopharyngodon idella).
Lymphoma, B-Cell
Paracaspase MALT1 regulates glioma cell survival by controlling endo-lysosome homeostasis.
Lymphoma, B-Cell
PCR array analysis identified hyperproliferation but not autophagy or apoptosis in fibrous epulis.
Lymphoma, B-Cell
Protease nexin-1 prevents growth of human B cell lymphoma via inhibition of sonic hedgehog signaling.
Lymphoma, B-Cell
Sedum takesimense Protects PC12 Cells against Corticosterone-Induced Neurotoxicity by Inhibiting Neural Apoptosis.
Lymphoma, B-Cell
Short-term heat stress causes altered intracellular signaling in oxidative skeletal muscle.
Lymphoma, B-Cell
Survival in HIV-infected patients with lymphoma according to the choice of antiretroviral treatment: an observational multicentre study.
Lymphoma, B-Cell
Synergistic Effect of Forbesione From Garcinia hanburyi in Combination with 5-Fluorouracil on Cholangiocarcinoma
Lymphoma, B-Cell
The ability of Ia and H-2Kk-bearing membranes to replace the antigen-presenting cell in an H-2Kk allogeneic cytotoxic T cell response.
Lymphoma, B-Cell
The Pivotal Role of Long Noncoding RNA RAB5IF in the Proliferation of Hepatocellular Carcinoma Via LGR5 Mediated ?-Catenin and c-Myc Signaling.
Lymphoma, B-Cell
The protease activity of the paracaspase MALT1 is controlled by monoubiquitination.
Lymphoma, B-Cell, Marginal Zone
A role for MALT1 activity in Kaposi's sarcoma-associated herpes virus latency and growth of primary effusion lymphoma.
Lymphoma, B-Cell, Marginal Zone
Antiapoptotic properties of MALT1 protease are associated with redox homeostasis in ABC-DLBCL cells.
Lymphoma, B-Cell, Marginal Zone
Backbone Assignment of the MALT1 Paracaspase by Solution NMR.
Lymphoma, B-Cell, Marginal Zone
GLS1-mediated glutaminolysis unbridled by MALT1 protease promotes psoriasis pathogenesis.
Lymphoma, B-Cell, Marginal Zone
MALT1 as a promising target to treat lymphoma and other diseases related to MALT1 anomalies.
Lymphoma, B-Cell, Marginal Zone
MALT1 Protease Activity Controls the Expression of Inflammatory Genes in Keratinocytes upon Zymosan Stimulation.
Lymphoma, B-Cell, Marginal Zone
Protease activity of the API2-MALT1 fusion oncoprotein in MALT lymphoma development and treatment.
Lymphoma, B-Cell, Marginal Zone
Structure elucidation and absolute configuration of metabolites from the soil-derived fungus Dictyosporium digitatum using spectroscopic and computational methods.
Lymphoma, Large B-Cell, Diffuse
Activity-based probes for detection of active MALT1 paracaspase in immune cells and lymphomas.
Lymphoma, Large B-Cell, Diffuse
Antiapoptotic properties of MALT1 protease are associated with redox homeostasis in ABC-DLBCL cells.
Lymphoma, Large B-Cell, Diffuse
Essential role of MALT1 protease activity in activated B cell-like diffuse large B-cell lymphoma.
Lymphoma, Large B-Cell, Diffuse
Identification of Novel Fused Heteroaromatics-Based MALT1 Inhibitors by High-Throughput Screening to Treat B Cell Lymphoma.
Lymphoma, Large B-Cell, Diffuse
Inhibition of MALT1 protease activity is selectively toxic for activated B cell-like diffuse large B cell lymphoma cells.
Lymphoma, Large B-Cell, Diffuse
Survival in HIV-infected patients with lymphoma according to the choice of antiretroviral treatment: an observational multicentre study.
Lymphoma, Large B-Cell, Diffuse
The protease activity of the paracaspase MALT1 is controlled by monoubiquitination.
Lymphoma, Large-Cell, Anaplastic
Prognostic significance of activated cytotoxic T-lymphocytes in primary nodal diffuse large B-cell lymphomas.
Lymphoma, Mantle-Cell
Small Molecule Inhibition of the Ubiquitin-specific Protease USP2 Accelerates cyclin D1 Degradation and Leads to Cell Cycle Arrest in Colorectal Cancer and Mantle Cell Lymphoma Models.
Lymphoma, Non-Hodgkin
Activation of a cyclic AMP-independent protein kinase by an endogenous ATP-requiring protease from lymphosarcoma cells.
Lymphoma, Non-Hodgkin
Cathepsin S Protease Mediates T-Cell Response in Non-Hodgkin Lymphoma.
Lymphoma, Non-Hodgkin
Differential effect of HIV-1 protease inhibitors on P-glycoprotein function in multidrug-resistant variants of the human CD4+ T lymphoblastoid CEM cell line.
Lymphoma, Non-Hodgkin
Pharmacokinetic interaction between chemotherapy for non-Hodgkin's lymphoma and protease inhibitors in HIV-1-infected patients.
Lymphoma, Non-Hodgkin
Protection against metastasis of radiation-induced thymic lymphosarcoma and weight loss in C57Bl/6NCr1BR mice by an autoclave-resistant factor present in soybeans.
Lymphoma, Non-Hodgkin
Remission of an HHV8-related extracavitary primary effusion lymphoma in an HIV-positive patient during antiretroviral treatment containing dolutegravir.
Lymphoma, Non-Hodgkin
Rituximab (anti-CD20) selectively modifies Bcl-xL and apoptosis protease activating factor-1 (Apaf-1) expression and sensitizes human non-Hodgkin's lymphoma B cell lines to paclitaxel-induced apoptosis.
Lymphoma, Non-Hodgkin
Rodent kinin-forming enzyme systems--II. Purification and characterization of an acid protease from Murphy-Sturm lymphosarcoma.
Lymphoma, Non-Hodgkin
Saquinavir enhances the mucosal toxicity of infusional cyclophosphamide, doxorubicin, and etoposide in patients with HIV-associated non-Hodgkin's lymphoma.
Lymphoma, T-Cell
A gammaherpesvirus ubiquitin-specific protease is involved in the establishment of murine gammaherpesvirus 68 infection.
Lymphoma, T-Cell
A herpesvirus ubiquitin-specific protease is critical for efficient T cell lymphoma formation.
Lymphoma, T-Cell
Effective inhibition of experimental metastasis and prolongation of survival in mice by a potent factor Xa-specific synthetic serine protease inhibitor with weak anticoagulant activity.
Lymphoma, T-Cell
Survival in HIV-infected patients with lymphoma according to the choice of antiretroviral treatment: an observational multicentre study.
Lymphoma, T-Cell
Synergistic antiviral effect of PEG-asparaginase (ONCASPAR), with protease inhibitor alone and in combination with RT inhibitors against HIV-1 infected T-cells: a model of HIV-1-induced T-cell lymphoma.
Lymphoma, T-Cell
The serine protease granzyme M is preferentially expressed in NK-cell, gamma delta T-cell, and intestinal T-cell lymphomas: evidence of origin from lymphocytes involved in innate immunity.
Lymphoma, T-Cell, Cutaneous
Ubiquitin-specific protease 2 decreases p53-dependent apoptosis in cutaneous T-cell lymphoma.
Lymphoproliferative Disorders
Characterization of a novel, human cytotoxic lymphocyte-specific serine protease cDNA clone (CSP-C).
lysine carboxypeptidase deficiency
Plasma protease inhibitor and anaphylatoxin inactivator levels in chronic urticaria/angioedema and in patients experiencing anaphylactoid reactions to radiographic contrast media.
Macular Degeneration
An association of neovascular age-related macular degeneration with polymorphisms of CFH, ARMS2, HTRA1 and C3 genes in Czech population.
Macular Degeneration
Biologically Active Fibronectin Fragments Stimulate Release of MCP-1 and Catabolic Cytokines from Murine Retinal Pigment Epithelium.
Macular Degeneration
HtrA1 Is Specifically Up-Regulated in Active Keloid Lesions and Stimulates Keloid Development.
Macular Degeneration
HTRA1, an age-related macular degeneration protease, processes extracellular matrix proteins EFEMP1 and TSP1.
Macular Degeneration
Inhibition of choroidal neovascularization by a peptide inhibitor of the urokinase plasminogen activator and receptor system in a mouse model.
Macular Degeneration
Small-molecule factor D inhibitors targeting the alternative complement pathway.
Macular Degeneration
The trimeric serine protease HtrA1 forms a cage-like inhibition complex with an anti-HtrA1 antibody.
Macular Edema
Cystoid macular edema in a patient with acquired immunodeficiency syndrome and past ocular history of cytomegalovirus retinitis after initiation of protease inhibitors.
Malabsorption Syndromes
Effect of malabsorption syndrome on pancreatic function in broilers.
Malaria
A gut-specific serine protease from the malaria vector Aanopheles gambiae is downregulated after blood ingestion.
Malaria
A malaria parasite subtilisin propeptide-like protein is a potent inhibitor of the egress protease SUB1.
Malaria
A modular chitin-binding protease associated with hemocytes and hemolymph in the mosquito Anopheles gambiae.
Malaria
A multifunctional serine protease primes the malaria parasite for red blood cell invasion.
Malaria
A protease cascade regulates release of the human malaria parasite Plasmodium falciparum from host red blood cells.
Malaria
A role for the protease falcipain 1 in host cell invasion by the human malaria parasite.
Malaria
A Serine Protease Homolog Negatively Regulates TEP1 Consumption in Systemic Infections of the Malaria Vector Anopheles gambiae.
Malaria
A single malaria merozoite serine protease mediates shedding of multiple surface proteins by juxtamembrane cleavage.
Malaria
Activated protein C protects vascular endothelial cells from apoptosis in malaria and in sepsis.
Malaria
An easter-like serine protease from Anopheles gambiae exhibits changes in transcript abundance following immune challenge.
Malaria
Anemia and Micronutrient Status during Pregnancy, and Their Associations with Obstetric and Infant Outcomes among HIV-Infected Ugandan Women Receiving Antiretroviral Therapy.
Malaria
Antiretroviral protease inhibitors potentiate chloroquine antimalarial activity in malaria parasites by regulating intracellular glutathione metabolism.
Malaria
Autocatalytic activation of a malarial egress protease is druggable and requires a protein cofactor.
Malaria
Brief Report: Antimalarial Benefit of HIV Antiretroviral Therapy in Areas of Low to Moderate Malaria Transmission Intensity.
Malaria
CaaX-Like Protease of Cyanobacterial Origin Is Required for Complex Plastid Biogenesis in Malaria Parasites.
Malaria
Characterization of the autophagy marker protein Atg8 reveals atypical features of autophagy in Plasmodium falciparum.
Malaria
Characterization of the Plasmodium falciparum M17 leucyl aminopeptidase. A protease involved in amino acid regulation with potential for antimalarial drug development.
Malaria
Chloroquine resistant malaria: association with enhanced plasmodial protease activity.
Malaria
CLIPB10 is a Terminal Protease in the Regulatory Network That Controls Melanization in the African Malaria Mosquito Anopheles gambiae.
Malaria
Cloning and characterization of a serine protease from the human malaria vector, Anopheles gambiae.
Malaria
Cloning and characterization of four Anopheles gambiae serpin isoforms, differentially induced in the midgut by Plasmodium berghei invasion.
Malaria
Cloning of a trypsin-like serine protease and expression patterns during Plasmodium falciparum invasion in the mosquito, Anopheles dirus (Peyton and Harrison).
Malaria
Computational prediction of structure, substrate binding mode, mechanism, and rate for a malaria protease with a novel type of active site.
Malaria
Correction: Picomolar Inhibition of Plasmepsin V, an Essential Malaria Protease, Achieved Exploiting the Prime Region.
Malaria
Disruption of rosetting in Plasmodium falciparum malaria with chemically modified heparin and low molecular weight derivatives possessing reduced anticoagulant and other serine protease inhibition activities.
Malaria
Distinct mechanisms govern proteolytic shedding of a key invasion protein in apicomplexan pathogens.
Malaria
Effect of antiretroviral therapy on malaria incidence in HIV-infected Ugandan adults.
Malaria
Effect of metalloprotease inhibitors on invasion of red blood cell by Plasmodium falciparum.
Malaria
Endoperoxide Carbonyl Falcipain 2/3 Inhibitor Hybrids: Toward Combination Chemotherapy of Malaria through a Single Chemical Entity.
Malaria
Estradiol Levels Are Altered in Human Immunodeficiency Virus-Infected Pregnant Women Randomized to Efavirenz-Versus Lopinavir/Ritonavir-Based Antiretroviral Therapy.
Malaria
Expression of recombinant Plasmodium falciparum subtilisin-like protease-1 in insect cells. Characterization, comparison with the parasite protease, and homology modeling.
Malaria
Expression of three serine protease genes from the South East Asian malaria vector, Anopheles dirus, in relation to blood feeding and parasite infection.
Malaria
Falstatin, a cysteine protease inhibitor of Plasmodium falciparum, facilitates erythrocyte invasion.
Malaria
Functional characterization of the propeptide of Plasmodium falciparum subtilisin-like protease-1.
Malaria
Genes identified by an expression screen of the vector mosquito Anopheles gambiae display differential molecular immune response to malaria parasites and bacteria.
Malaria
High-affinity inhibition of a family of Plasmodium falciparum proteases by a designed adaptive inhibitor.
Malaria
Identification of electrophoretically separated proteases from midgut and hemolymph of adult Anopheles stephensi mosquitoes.
Malaria
Malaria in HIV-Infected Children Receiving HIV Protease-Inhibitor- Compared with Non-Nucleoside Reverse Transcriptase Inhibitor-Based Antiretroviral Therapy, IMPAACT P1068s, Substudy to P1060.
Malaria
Malaria Parasite Signal Peptide Peptidase is an ER-Resident Protease Required for Growth but not for Invasion.
Malaria
Malaria proteases mediate inside-out egress of gametocytes from red blood cells following parasite transmission to the mosquito.
Malaria
Molecular characterization of five serine protease genes cloned from Anopheles gambiae hemolymph.
Malaria
Multiple sclerosis-like diagnosis as a complication of previously treated malaria in an iron and vitamin D deficient Nigerian patient.
Malaria
Non-detergent sulphobetaines: a new class of mild solubilization agents for protein purification.
Malaria
Optimization of a multi-stage, multi-subunit malaria vaccine candidate for the production in Pichia pastoris by the identification and removal of protease cleavage sites.
Malaria
Parasite killing in Plasmodium vivax malaria by nitric oxide: implication of aspartic protease inhibition.
Malaria
Peptidic boronic acids are potent cell-permeable inhibitors of the malaria parasite egress serine protease SUB1.
Malaria
Peritrophic membranes and protease activity in the midgut of the malaria mosquito, Anopheles stephensi (Liston) (Insecta: Diptera) under normal and experimental conditions.
Malaria
Picomolar Inhibition of Plasmepsin V, an Essential Malaria Protease, Achieved Exploiting the Prime Region.
Malaria
Plasmodium falciparum and Plasmodium chabaudi: characterization of glycosylphosphatidylinositol-degrading activities.
Malaria
Potencies of human immunodeficiency virus protease inhibitors in vitro against Plasmodium falciparum and in vivo against murine malaria.
Malaria
Prevalence of Asymptomatic Parasitemia and Gametocytemia among HIV-Infected Ugandan Children Randomized to Receive Different Antiretroviral Therapies.
Malaria
Prevalence of Plasmodium falciparum delayed clearance associated polymorphisms in adaptor protein complex 2 mu subunit (pfap2mu) and ubiquitin specific protease 1 (pfubp1) genes in Ghanaian isolates.
Malaria
Protective immune responses against protease-like antigens of the murine malaria parasite Plasmodium vinckei.
Malaria
Publisher Correction: A protease cascade regulates release of the human malaria parasite Plasmodium falciparum from host red blood cells.
Malaria
Serum alpha-1 antichymotrypsin is a possible growth inhibitor of Plasmodium falciparum.
Malaria
Stronger activity of human immunodeficiency virus type 1 protease inhibitors against clinical isolates of Plasmodium vivax than against those of P. falciparum.
Malaria
Subcellular discharge of a serine protease mediates release of invasive malaria parasites from host erythrocytes.
Malaria
Synergy of the antiretroviral protease inhibitor indinavir and chloroquine against malaria parasites in vitro and in vivo.
Malaria
Targeting the Plasmodium falciparum plasmepsin V by ligand-based virtual screening.
Malaria
The CLIP-domain serine protease CLIPC9 regulates melanization downstream of SPCLIP1, CLIPA8, and CLIPA28 in the malaria vector Anopheles gambiae.
Malaria
The CLIP-Domain Serine Protease Homolog SPCLIP1 Regulates Complement Recruitment to Microbial Surfaces in the Malaria Mosquito Anopheles gambiae.
Malaria
The malaria parasite egress protease SUB1 is a calcium-dependent redox switch subtilisin.
Malaria
The serine protease homolog CLIPA14 modulates the intensity of the immune response in the mosquito Anopheles gambiae.
Malaria
Transcriptional analysis of an immune-responsive serine protease from Indian malarial vector, Anopheles culicifacies.
Malaria, Cerebral
Serum alpha-1 antichymotrypsin is a possible growth inhibitor of Plasmodium falciparum.
Malaria, Falciparum
Disruption of rosetting in Plasmodium falciparum malaria with chemically modified heparin and low molecular weight derivatives possessing reduced anticoagulant and other serine protease inhibition activities.
Malformations of Cortical Development, Group II
The function of presenilin-1 in amyloid beta-peptide generation and brain development.
Malnutrition
Bioelectrical impedance analysis in HIV-infected patients treated with triple antiretroviral treatment.
Malnutrition
Hypogonadotropic hypogonadism in human immunodeficiency virus-infected men: uncommonly low testosterone levels.
Malnutrition
Lack of evidence for elevated breakdown rate of skeletal muscles in weight-losing, tumor-bearing mice.
Malnutrition
Prevalence, Risk Factors, and Pathophysiology of Dysglycemia among People Living with HIV in Sub-Saharan Africa.
Mandibular Fractures
[Effect of a protease inhibitor on the process of bone tissue mineralization in the healing of mandibular fractures]
Marek Disease
A gammaherpesvirus ubiquitin-specific protease is involved in the establishment of murine gammaherpesvirus 68 infection.
Marek Disease
Marek's disease virus (MDV) ubiquitin-specific protease (USP) performs critical functions beyond its enzymatic activity during virus replication.
Marek Disease
Sequential autoprocessing of Marek's disease herpesvirus protease differs from that of other herpesviruses.
Marfan Syndrome
Classical and neonatal Marfan syndrome mutations in fibrillin-1 cause differential protease susceptibilities and protein function.
Massive Hepatic Necrosis
Significance of tumor necrosis factor (TNF) and interleukin-1 (IL-1) in the pathogenesis of fulminant hepatitis: possible involvement of serine protease in TNF-mediated liver injury.
Massive Hepatic Necrosis
[Clinical trial of protease inhibitor in the treatment of fulminant hepatitis]
Mastitis
A simple identification scheme for coagulase negative staphylococci from bovine mastitis.
Mastitis
Analysis of Milk from Mothers Who Delivered Prematurely Reveals Few Changes in Proteases and Protease Inhibitors across Gestational Age at Birth and Infant Postnatal Age.
Mastitis
Short communication: Protease activity measurement in milk as a diagnostic test for clinical mastitis in dairy cows.
Mastocytoma
Chymase and tryptase in dog mastocytoma cells: asynchronous expression as revealed by enzyme cytochemical staining.
Mastocytoma
Dog mast cell alpha-chymase activates progelatinase B by cleaving the Phe88-Gln89 and Phe91-Glu92 bonds of the catalytic domain.
Mastocytoma
Dog mastocytoma cells secrete a 92-kD gelatinase activated extracellularly by mast cell chymase.
Mastocytoma
Dog mastocytoma tryptase: affinity purification, characterization, and amino-terminal sequence.
Mastocytoma
Expression and utilization of chymotrypsin-like but not trypsin-like serine protease enzymes by nonspecific T killer cells activated by anti-CD3 monoclonal antibody.
Mastocytoma
Generation of active myeloid and lymphoid granule serine proteases requires processing by the granule thiol protease dipeptidyl peptidase I.
Mastocytoma
Mast cell and neutrophil expression of dog mast cell protease-3. A novel tryptase-related serine protease.
Mastocytoma
Tryptase and chymase: comparison of extraction and release in two dog mastocytoma lines.
Mastocytosis
Altered expression of mast cell proteases in the rat. Quantitative and immunohistochemical analysis of the distribution of rat mast cell proteases I and II during helminth infection.
Mastocytosis
Conditioned media from a cell strain derived from a patient with mastocytosis induces preferential development of cells that possess high affinity IgE receptors and the granule protease phenotype of mature cutaneous mast cells.
Mastocytosis
Expulsion of Secondary Trichinella spiralis Infection in Rats Occurs Independently of Mucosal Mast Cell Release of Mast Cell Protease II.
Mastocytosis
Inflammatory responses in the intestine during tapeworm infections. Mucosal mast cells and mucosal mast cell proteases in Sprague-Dawley rats infected with Hymenolepis diminuta.
Mastocytosis, Systemic
Protease profile of normal and neoplastic mast cells in the human bone marrow with special emphasis on systemic mastocytosis.
Mastocytosis, Systemic
The alpha form of human tryptase is the predominant type present in blood at baseline in normal subjects and is elevated in those with systemic mastocytosis.
Maxillary Sinusitis
[Enzymatic study on the mucus membrane in upper maxillary sinusitis and the effects of radioactive iodine-labelled alpha-chymotrypsin on protease activity]
Measles
AR-12 Inhibits Multiple Chaperones Concomitant With Stimulating Autophagosome Formation Collectively Preventing Virus Replication.
Measles
Engineered serine protease inhibitor prevents furin-catalyzed activation of the fusion glycoprotein and production of infectious measles virus.
Measles
Isolation of the measles virus hemagglutinin protein in a soluble form by protease digestion.
Measles
Liver cancer protease activity profiles support therapeutic options with matrix metalloproteinase-activatable oncolytic measles virus.
Measles
Recombinant measles virus requiring an exogenous protease for activation of infectivity.
Measles
The protease inhibitor TLCK alters the apparent molecular weights of some measles virus proteins by a mechanism unrelated to inhibition of proteolytic cleavage.
Mediastinitis
[Effect of reinfusion of UV-irradiated blood on the activity of the kallikrein-kinin system in patients with diffuse phlegmons of the face and neck]
Medulloblastoma
Molecular genetic analysis of the hepatocyte growth factor/MET signaling pathway in pediatric medulloblastoma.
Medulloblastoma
Serpine2/PN-1 Is Required for Proliferative Expansion of Pre-Neoplastic Lesions and Malignant Progression to Medulloblastoma.
Medulloblastoma
Suppression of uPAR retards radiation-induced invasion and migration mediated by integrin ?1/FAK signaling in medulloblastoma.
Melanoma
A 170-kDa membrane-bound protease is associated with the expression of invasiveness by human malignant melanoma cells.
Melanoma
A matrix metalloproteinase-1/protease activated receptor-1 signaling axis promotes melanoma invasion and metastasis.
Melanoma
A potential marker protease of invasiveness, seprase, is localized on invadopodia of human malignant melanoma cells.
Melanoma
Antimetastatic activity of boro-amino acid analog protease inhibitors against B16BL6 melanoma in vivo.
Melanoma
Apoptosis induced by ursodeoxycholic acid in human melanoma cells through the mitochondrial pathway.
Melanoma
Apoptosis protease activator protein-1 expression is dispensable for response of human melanoma cells to distinct proapoptotic agents.
Melanoma
ATP-dependent Lon protease controls tumor bioenergetics by reprogramming mitochondrial activity.
Melanoma
Cell-surface proteolysis, growth factor activation and intercellular communication in the progression of melanoma.
Melanoma
Characterization of seven human melanoma cell lines: melanogenesis and secretion of plasminogen activators.
Melanoma
Cloning and characterization of human ubiquitin-processing protease-43 from terminally differentiated human melanoma cells using a rapid subtraction hybridization protocol RaSH.
Melanoma
Cytokine-dependent invasiveness in B16 murine melanoma cells: role of uPA system and MMP-9.
Melanoma
Different roles for plasminogen activators and metalloproteinases in melanoma metastasis.
Melanoma
Dipeptidyl peptidase IV (DPPIV), a candidate tumor suppressor gene in melanomas is silenced by promoter methylation.
Melanoma
Double-stranded RNA-induced interferon-beta and inflammatory cytokine production modulated by hepatitis C virus serine proteases derived from patients with hepatic diseases.
Melanoma
Effects of Alpha-Connexin Carboxyl-Terminal Peptide (aCT1) and Bowman-Birk Protease Inhibitor (BBI) on Canine Oral Mucosal Melanoma (OMM) Cells.
Melanoma
Epigenetic regulation of the transcription factor Foxa2 directs differential elafin expression in melanocytes and melanoma cells.
Melanoma
Estradiol-induced biochemical changes in human neoplastic cells: estradiol-mediated protease.
Melanoma
Exosome-mediated uptake of mast cell tryptase into the nucleus of melanoma cells: a novel axis for regulating tumor cell proliferation and gene expression.
Melanoma
Expression of the apoptosis inhibitor protease inhibitor 9 predicts clinical outcome in vaccinated patients with stage III and IV melanoma.
Melanoma
Expression of tissue factor by melanoma cells promotes efficient hematogenous metastasis.
Melanoma
Extracellular Protease ADAMTS1 Is Required at Early Stages of Human Uveal Melanoma Development by Inducing Stemness and Endothelial-Like Features on Tumor Cells.
Melanoma
Fibrin serves as a divalent ligand that regulates neutrophil-mediated melanoma cells adhesion to endothelium under shear conditions.
Melanoma
Gradient centrifugation analysis of steroid-hormone binding in human malignant melanoma.
Melanoma
Human skin fibroblast stromelysin: structure, glycosylation, substrate specificity, and differential expression in normal and tumorigenic cells.
Melanoma
Identification of a novel recognition sequence for the integrin alpha 4 beta 1 in the COOH-terminal heparin-binding domain of fibronectin.
Melanoma
Identification of differentially expressed genes in models of melanoma progression by cDNA array analysis: SPARC, MIF and a novel cathepsin protease characterize aggressive phenotypes.
Melanoma
Identification of the 170-kDa melanoma membrane-bound gelatinase (seprase) as a serine integral membrane protease.
Melanoma
Immune-Complexed Adenovirus Induce AIM2-Mediated Pyroptosis in Human Dendritic Cells.
Melanoma
Immunochemical characterization of a tumor-associated antigen defined by a monoclonal antibody.
Melanoma
Improved detection of labile cell-surface components with zinc chloride-aprotinin: demonstration of glycoprotein differences in K-1735 metastatic melanoma variants.
Melanoma
Inhibition of the human tissue plasminogen activator in plasma from different species.
Melanoma
Invasion of melanoma cells by Mycoplasma hyorhinis: enhancement by protease treatment.
Melanoma
Kunitz type protease inhibitor from the canine tapeworm as a potential therapeutic for melanoma.
Melanoma
Loss of maspin expression contributes to a more invasive potential in malignant melanoma.
Melanoma
Low levels of urokinase plasminogen activator components in basal cell carcinoma of the skin.
Melanoma
MEK2 is sufficient but not necessary for proliferation and anchorage-independent growth of SK-MEL-28 melanoma cells.
Melanoma
Melanoma cell migration on vitronectin: regulation by components of the plasminogen activation system.
Melanoma
Melanoma invasion in reconstructed human skin is influenced by skin cells--investigation of the role of proteolytic enzymes.
Melanoma
Microtubule-dependent matrix metalloproteinase-2/matrix metalloproteinase-9 exocytosis: prerequisite in human melanoma cell invasion.
Melanoma
Molecular basis of complement resistance of human melanoma cells expressing the C3-cleaving membrane protease p65.
Melanoma
Molecular cloning of seprase: a serine integral membrane protease from human melanoma.
Melanoma
Neuronal NLRP1 inflammasome activation of Caspase-1 coordinately regulates inflammatory interleukin-1-beta production and axonal degeneration-associated Caspase-6 activation.
Melanoma
Noncanonical Activation of Notch1 Protein by Membrane Type 1 Matrix Metalloproteinase (MT1-MMP) Controls Melanoma Cell Proliferation.
Melanoma
Potential MMP2-mediated availability of HLA binding, mutant ECM peptides reflects better melanoma survival rates and greater T-cell infiltrates.
Melanoma
Preclinical evaluation of Amblyomin-X, a Kunitz-type protease inhibitor with antitumor activity.
Melanoma
Protease activated receptor-1 inhibits the Maspin tumor-suppressor gene to determine the melanoma metastatic phenotype.
Melanoma
Proteolytic cleavage of Livin (ML-IAP) in apoptotic melanoma cells potentially mediated by a non-canonical caspase.
Melanoma
Regulatory and functional connection of microphthalmia-associated transcription factor and anti-metastatic pigment epithelium derived factor in melanoma.
Melanoma
Relationship between cell surface protease activity and doubling time in various normal and transformed cells.
Melanoma
Seprase, a membrane-bound protease, is overexpressed by invasive ductal carcinoma cells of human breast cancers.
Melanoma
Soluble CD44 inhibits melanoma tumor growth by blocking cell surface CD44 binding to hyaluronic acid.
Melanoma
Spatial orientation of tissue-type plasminogen activator bound at the melanoma cell surface.
Melanoma
Stroma-derived but not tumor ADAMTS1 is a main driver of tumor growth and metastasis.
Melanoma
The combined action of mast cell chymase, tryptase and carboxypeptidase A3 protects against melanoma colonization of the lung.
Melanoma
The effect of trasylol (Trascolan "Polfa") and p-aminomethylbenzoic acid (Pamba "Germed") on the experimental metastases of transplantable melanotic melanoma in golden hamster (Mesocricetus auratus, Waterhouse)
Melanoma
The Emerging Role of the Thrombin Receptor (PAR-1) in Melanoma Metastasis - a Possible Therapeutic Target.
Melanoma
The field bean protease inhibitor has the potential to suppress B16F10 melanoma cell lung metastasis in mice.
Melanoma
The HtrA1 serine protease is down-regulated during human melanoma progression and represses growth of metastatic melanoma cells.
Melanoma
The influence of the protease inhibitor aprotinin on tumor invasion of three cell lines in vitro.
Melanoma
The membrane tethered matrix metalloproteinase MT1-MMP at the forefront of melanoma cell invasion and metastasis.
Melanoma
The protease inhibitor, elafin, induces p53-dependent apoptosis in human melanoma cells.
Melanoma
The receptor for urokinase-plasminogen activator (uPAR) controls plasticity of cancer cell movement in mesenchymal and amoeboid migration style.
Melanoma
The ubiquitin-specific protease 17 is involved in virus-triggered type I IFN signaling.
Melanoma
Therapeutic Potential of Medicinal Plant Proteins: Present Status and Future Perspectives.
Melanoma
TNF-alpha increases human melanoma cell invasion and migration in vitro: the role of proteolytic enzymes.
Melanoma
Transmigration of melanoma cells through the blood-brain barrier: role of endothelial tight junctions and melanoma-released serine proteases.
Melanoma
Unequal forms of 140-110 kD glycoproteins in B16 melanoma cells with differing detachment properties and metastatic behavior: influence of bromodeoxyuridine.
Melanoma
Unique antineoplastic profile of Saquinavir-NO, a novel NO-derivative of the protease inhibitor Saquinavir, on the in vitro and in vivo tumor formation of A375 human melanoma cells.
Melanoma
Up-regulation of Flotillin-2 is associated with melanoma progression and modulates expression of the thrombin receptor protease activated receptor 1.
Melanoma
USP22 deficiency in melanoma mediates resistance to T cells through IFN?-JAK1-STAT1 signal axis.
Melanoma
USP5 promotes tumorigenesis and progression of pancreatic cancer by stabilizing FoxM1 protein.
Melanoma
Vitamin D-induced apoptosis and melanoma: does calpain represent the major execution protease rather than caspases?
Melanoma
[Endogenous Tumor necrosis factor alpha unmasks the binding sites for N-acetylglucosaminyl-(beta1-4)-N-acetylmuramyl-alanyl-D-isoglutamine on the surface of melanoma cells]
Melanoma, Experimental
Differences in induction of lysosomal protease activity by protease inhibitors in B16 melanoma cell lines.
Melanoma, Experimental
Unequal forms of 140-110 kD glycoproteins in B16 melanoma cells with differing detachment properties and metastatic behavior: influence of bromodeoxyuridine.
MELAS Syndrome
Activation of the mitochondrial protein quality control system and actin cytoskeletal alterations in cells harbouring the MELAS mitochondrial DNA mutation.
Memory Disorders
A serine protease KLK8 emerges as a regulator of regulators in memory: Microtubule protein dependent neuronal morphology and PKA-CREB signaling.
Memory Disorders
Deletion of the Cathepsin B Gene Improves Memory Deficits in a Transgenic Alzheimer's Disease Mouse Model Expressing A?PP Containing the Wild-Type ?-Secretase Site Sequence.
Memory Disorders
Learning and memory deficits in mice lacking protease activated receptor-1.
Meningioma
Expression of matrix metalloproteinases, their inhibitors, and urokinase plasminogen activator in human meningiomas.
Meningioma
Molecular alterations in the neurofibromatosis type 2 gene and its protein rarely occurring in meningothelial meningiomas.
Meningioma
RNAi-mediated downregulation of urokinase plasminogen activator and its receptor in human meningioma cells inhibits tumor invasion and growth.
Meningioma
Tight association of loss of merlin expression with loss of heterozygosity at chromosome 22q in sporadic meningiomas.
Meningitis
Central nervous system HIV replication and HIV-related pachymeningitis in a patient on protease inhibitor monotherapy despite an undetectable plasma viral load.
Meningitis
Concentrations of insulin-like growth factor (IGF)-binding protein-3 (IGFBP-3), IGF, and IGFBP-3 protease activity in cerebrospinal fluid of children with leukemia, central nervous system tumor, or meningitis.
Meningitis
Degradation of immunoglobulins A2, A2, and G by suspected principal periodontal pathogens.
Meningitis
Increased permeability of blood-brain barrier is mediated by serine protease during Cryptococcus meningitis.
Meningitis
[Elastase-like protease activity in the granulocytes and the level of acid-stable inhibitors in the cerebrospinal fluid of children with suppurative meningitis]
Meningitis, Bacterial
Nuclear trafficking, histone cleavage and induction of apoptosis by the meningococcal App and MspA autotransporters.
Meningitis, Cryptococcal
Voriconazole use and pharmacokinetics in combination with interferon-gamma for refractory cryptococcal meningitis in a patient receiving low-dose ritonavir.
Meningococcal Infections
Neisseria meningitidis IgA1-specific serine protease exhibits novel cleavage activity against IgG3.
Meningoencephalitis
The human immunodeficiency virus (HIV) protease inhibitor indinavir directly affects the opportunistic fungal pathogen Cryptococcus neoformans.
MERRF Syndrome
Mitochondrial DNA Mutation-Elicited Oxidative Stress, Oxidative Damage, and Altered Gene Expression in Cultured Cells of Patients with MERRF Syndrome.
Mesothelioma
Aberrant splicing and protease involvement in mesothelin release from epithelioid mesothelioma cells.
Mesothelioma
Biochemical characterization of hyaluronic acid from a case of benign, localized, pleural mesothelioma.
Mesothelioma
Bowman-Birk protease inhibitor from soybeans enhances cisplatin-induced cytotoxicity in human mesothelioma cells.
Mesothelioma
Endothelial Cell Protein C Receptor Opposes Mesothelioma Growth Driven by Tissue Factor.
Mesothelioma
Extracellular protease imaging for cell mass tracking of xenografted human malignant pleural mesothelioma.
Mesothelioma
Hepatocyte growth factor/scatter factor enhances the invasion of mesothelioma cell lines and the expression of matrix metalloproteinases.
Mesothelioma
The serine protease HtrA1 is a novel prognostic factor for human mesothelioma.
Mesothelioma, Malignant
Endothelial Cell Protein C Receptor Opposes Mesothelioma Growth Driven by Tissue Factor.
Mesothelioma, Malignant
Extracellular protease imaging for cell mass tracking of xenografted human malignant pleural mesothelioma.
Mesothelioma, Malignant
Targeting CD26 suppresses proliferation of malignant mesothelioma cell via downmodulation of ubiquitin-specific protease 22.
Mesothelioma, Malignant
The serine protease HtrA1 is a novel prognostic factor for human mesothelioma.
Metabolic Diseases
Macrophage ubiquitin-specific protease 2 modifies insulin sensitivity in obese mice.
Metabolic Diseases
Protease activated receptor 2 (PAR2) modulators: a patent review (2010-2015).
Metabolic Diseases
Protective role of serpina3c as a novel thrombin inhibitor against atherosclerosis in mice.
Metabolic Diseases
Targeting Enteropeptidase with Reversible Covalent Inhibitors To Achieve Metabolic Benefits.
Metabolic Diseases
The adipokine vaspin is associated with decreased coronary in-stent restenosis in vivo and inhibits migration of human coronary smooth muscle cells in vitro.
Metabolic Diseases
Vaspin prevents elevation of blood pressure through inhibition of peripheral vascular remodeling in spontaneously hypertensive rats.
Metabolic Diseases
What can be learned in the snake antivenom field from the developments in human plasma derived products?
Metabolic Syndrome
A serine protease inhibitor camostat mesilate prevents podocyte apoptosis and attenuates podocyte injury in metabolic syndrome model rats.
Metabolic Syndrome
Abnormalities in plasma fatty acid composition in human immunodeficiency virus-infected children treated with protease inhibitors.
Metabolic Syndrome
Association Between the Framingham Risk Score and Carotid Artery Intima-Media Thickness in Patients With Human Immunodeficiency Virus.
Metabolic Syndrome
Association between the use of protease inhibitors in highly active antiretroviral therapy and incidence of diabetes mellitus and/or metabolic syndrome in HIV-infected patients: A systematic review and meta-analysis.
Metabolic Syndrome
Carotid intimal medial thickness in human immunodeficiency virus-infected women: effects of protease inhibitor use, cardiac risk factors, and the metabolic syndrome.
Metabolic Syndrome
Coronary Heart Disease (CHD) Risk Factors and Metabolic Syndrome in HIV-Positive Drug Users in Miami.
Metabolic Syndrome
Effect of metformin and rosiglitazone on lipid metabolism in HIV infected patients receiving protease inhibitor containing HAART.
Metabolic Syndrome
Functions of NQO1 in Cellular Protection and CoQ10 Metabolism and its Potential Role as a Redox Sensitive Molecular Switch.
Metabolic Syndrome
Heart and HAART: Two sides of the coin for HIV-associated cardiology issues.
Metabolic Syndrome
High-sensitivity C-reactive protein levels in HIV-infected patients treated or not with antiretroviral drugs and their correlation with factors related to cardiovascular risk and HIV infection.
Metabolic Syndrome
Highly active antiretroviral therapy-associated metabolic syndrome and cardiovascular risk.
Metabolic Syndrome
Highly active antiretroviral therapy-associated metabolic syndrome: pathogenesis and cardiovascular risk.
Metabolic Syndrome
HIV, metabolic syndrome X, inflammation, oxidative stress, and coronary heart disease risk : role of protease inhibitor exposure.
Metabolic Syndrome
Metabolic and cardiovascular complications of highly active antiretroviral therapy for HIV infection.
Metabolic Syndrome
Metabolic and neurologic consequences of chronic lopinavir/ritonavir administration to C57BL/6 mice.
Metabolic Syndrome
Metabolic disorders and cardiovascular risk in treatment-naïve HIV-infected patients of Sub-Saharan origin starting antiretrovirals: impact of westernized lifestyle.
Metabolic Syndrome
Metabolic Disorders in HIV-Infected Adolescents Receiving Protease Inhibitors.
Metabolic Syndrome
Metabolic syndrome among HIV-infected patients: prevalence, characteristics, and related factors.
Metabolic Syndrome
Micronised fenofibrate: an updated review of its clinical efficacy in the management of dyslipidaemia.
Metabolic Syndrome
Prevalence of metabolic syndrome in HIV-infected patients receiving highly active antiretroviral therapy using International Diabetes Foundation and Adult Treatment Panel III criteria: associations with insulin resistance, disturbed body fat compartmentalization, elevated C-reactive protein, and [corrected] hypoadiponectinemia.
Metabolic Syndrome
Prevalence of Metabolic Syndrome in Patients with HIV in the Era of Highly Active Antiretroviral Therapy.
Metabolic Syndrome
Recent Developments regarding Human Immunodeficiency Virus Infection and Stroke.
Metabolic Syndrome
Reviewing the cardiovascular complications of HIV infection after the introduction of highly active antiretroviral therapy.
Metabolic Syndrome
Therapeutic dose of HIV-1 protease inhibitor saquinavir does not permanently influence early insulin signaling.
Metabolic Syndrome
Treatment of HIV-associated dyslipidemia: a role for omega-3 fatty acids.
Metabolic Syndrome
Vitamin D insufficiency is associated with subclinical atherosclerosis in HIV-1-infected patients on combination antiretroviral therapy.
Metrorrhagia
Differential expression of conserved protease genes in crucifer-attacking pathovars of Xanthomonas campestris.
Metrorrhagia
Imaging of protease functions--current guide to spotting cysteine cathepsins in classical and novel scenes of action in mammalian epithelial cells and tissues.
Microcephaly
LONP1 de novo dominant mutation causes mitochondrial encephalopathy with loss of LONP1 chaperone activity and excessive LONP1 proteolytic activity.
Microphthalmos
Alteration of the serine protease PRSS56 causes angle-closure glaucoma in mice and posterior microphthalmia in humans and mice.
Microphthalmos
Differential expression of cathepsin K in neoplasms harboring TFE3 gene fusions.
Microscopic Polyangiitis
Antibodies to selected minor target antigens in patients with anti-neutrophil cytoplasmic antibodies (ANCA).
Microscopic Polyangiitis
Distinct differences in autoantigen specificity of anti-neutrophil cytoplasm antibodies in systemic vasculitides and other inflammatory diseases.
Microsporidiosis
Inhibitory activity of human immunodeficiency virus aspartyl protease inhibitors against Encephalitozoon intestinalis evaluated by cell culture-quantitative PCR assay.
Migraine Disorders
(292) Protease activated receptor 2 (PAR2) is a mediator of nociception in a mouse model of migraine.
Migraine Disorders
Characterization and preclinical evaluation of a protease activated receptor 2 (PAR2) monoclonal antibody as a preventive therapy for migraine.
Migraine Disorders
Protease activated receptor 2 (PAR2) activation causes migraine-like pain behaviors in mice.
Mite Infestations
Study of defense-related gene expression in grapevine infested by Colomerus vitis (Acari: Eriophyidae).
Mitochondrial Diseases
A salvage pathway maintains highly functional respiratory complex I.
Mitochondrial Diseases
Cell stress management by the mitochondrial LonP1 protease - Insights into mitigating developmental, oncogenic and cardiac stress.
Mitochondrial Diseases
Defective mitochondrial protease LonP1 can cause classical mitochondrial disease.
Mitochondrial Diseases
Spondyloepimetaphyseal dysplasia with neurodegeneration associated with AIFM1 mutation - a novel phenotype of the mitochondrial disease.
Molluscum Contagiosum
A novel family of viral death effector domain-containing molecules that inhibit both CD-95- and tumor necrosis factor receptor-1-induced apoptosis.
Mononeuropathies
[A case of Sjögren's syndrome and systemic sclerosis complicated with acute pancreatitis]
Motor Neuron Disease
Three-dimensional reconstruction of the S885A mutant of human mitochondrial Lon protease.
Mouth Diseases
Biologically active protease of foot and mouth disease virus is expressed from cloned viral cDNA in Escherichia coli.
Mouth Diseases
In vitro and in vivo studies of the Yrp1 protease from Yersinia ruckeri and its role in protective immunity against enteric red mouth disease of salmonids.
Mouth Diseases
L protease from foot and mouth disease virus confers eIF2-independent translation for mRNAs bearing picornavirus IRES.
Mouth Neoplasms
Combinations of SERPINB5 gene polymorphisms and environmental factors are associated with oral cancer risks.
Mouth Neoplasms
Impact of Maspin Polymorphism rs2289520 G/C and Its Interaction with Gene to Gene, Alcohol Consumption Increase Susceptibility to Oral Cancer Occurrence.
Mouth Neoplasms
Maspin expression, angiogenesis, prognostic parameters, and outcome in malignant melanoma.
Mouth Neoplasms
Quantitative proteomic analysis of oral brush biopsies identifies secretory leukocyte protease inhibitor as a promising, mechanism-based oral cancer biomarker.
Mouth Neoplasms
Relationship between protease activity and neu oncogene expression in patients with oral leukoplakia treated with the Bowman Birk Inhibitor.
Mouth Neoplasms
Sentrin/small ubiquitin-like modifier-specific protease 5 protects oral cancer cells from oxidative stress-induced apoptosis.
Mouth Neoplasms
Serine protease inhibitor (SERPIN) B1 promotes oral cancer cell motility and is over-expressed in invasive oral squamous cell carcinoma.
Mouth Neoplasms
The expression of E-cadherin and cathepsin-D in normal oral mucosa, oral epithelial dysplasia and oral squamous cell carcinoma: A comparative analysis between immunohistochemistry and routine histopathology.
Mouth Neoplasms
The inhibitory effects of immunosuppressive factors, dexamethasone and interleukin-4, on NF-kappaB-mediated protease production by oral cancer.
Mouth Neoplasms
Ubiquitin-specific protease 14 regulates cell proliferation and apoptosis in oral squamous cell carcinoma.
Moyamoya Disease
Loss of mitochondrial ClpP, Lonp1, and Tfam triggers transcriptional induction of Rnf213, a susceptibility factor for moyamoya disease.
Mucocutaneous Lymph Node Syndrome
Complement and protease inhibitors in the mucocutaneous lymph node syndrome.
Mucocutaneous Lymph Node Syndrome
Potential New Treatments for Kawasaki Disease, Its Variations, and Multisystem Inflammatory Syndrome.
Mucocutaneous Lymph Node Syndrome
The role of bacterial lipopolysaccharide-bound neutrophils in the pathogenesis of Kawasaki disease.
Mucocutaneous Lymph Node Syndrome
[Clinical utility of ulinastatin, urinary protease inhibitor in acute Kawasaki disease]
Mucopolysaccharidoses
Glycosaminoglycan-Mediated Loss of Cathepsin K Collagenolytic Activity in MPS I Contributes to Osteoclast and Growth Plate Abnormalities.
Mucormycosis
Pathogenicity patterns of mucormycosis: epidemiology, interaction with immune cells and virulence factors.
Mucositis
Saquinavir enhances the mucosal toxicity of infusional cyclophosphamide, doxorubicin, and etoposide in patients with HIV-associated non-Hodgkin's lymphoma.
Mulibrey Nanism
A diverse family of proteins containing tumor necrosis factor receptor-associated factor domains.
Multiple Myeloma
Cost of paid transplantation abroad: possible donor-origin early multiple myeloma in a renal transplant recipient treated using bortezomib.
Multiple Myeloma
Gambogenic acid synergistically potentiates bortezomib-induced apoptosis in multiple myeloma.
Multiple Myeloma
HIV-1 protease inhibitor induces growth arrest and apoptosis of human multiple myeloma cells via inactivation of signal transducer and activator of transcription 3 and extracellular signal-regulated kinase 1/2.
Multiple Myeloma
IGFBP-1 protease activity and IGFBP-1 fragments in a patient with multiple myeloma.
Multiple Myeloma
Improved nonclinical safety profile of a novel, highly selective inhibitor of the immunoproteasome subunit LMP7 (M3258).
Multiple Myeloma
Incidence of neutropenia and use of granulocyte colony-stimulating factors in multiple myeloma: is current clinical practice adequate?
Multiple Myeloma
Multiple myeloma cells catalyze hepatocyte growth factor (HGF) activation by secreting the serine protease HGF-activator.
Multiple Myeloma
Specific cleavage of insulin-like growth factor-binding protein-1 by a novel protease activity.
Multiple Myeloma
Synergistic Efficacy of the Demethylation Agent Decitabine in Combination With the Protease Inhibitor Bortezomib for Treating Multiple Myeloma Through the Wnt/?-Catenin Pathway.
Multiple Myeloma
The Mitochondrial Protease LonP1 Promotes Proteasome Inhibitor Resistance in Multiple Myeloma.
Multiple Myeloma
The role of Ubiquitin-specific protease 14 (USP14) in cell adhesion-mediated drug resistance(CAM-DR) of multiple myeloma cells.
Multiple Myeloma
The ubiquitin-proteasome system in prostate cancer and its transition to castration resistance.
Multiple Sclerosis
Altered proteolytic events in experimental autoimmune encephalomyelitis discovered by iTRAQ shotgun proteomics analysis of spinal cord.
Multiple Sclerosis
Biochemical characterization and N-terminomics analysis of leukolysin, the membrane-type 6 matrix metalloprotease (MMP25): chemokine and vimentin cleavages enhance cell migration and macrophase phagocytic activities.
Multiple Sclerosis
Differential expression of protease M/neurosin in oligodendrocytes and their progenitors in an animal model of multiple sclerosis.
Multiple Sclerosis
Gelatinase in the cerebrospinal fluid of patients with multiple sclerosis and other inflammatory neurological disorders.
Multiple Sclerosis
Human kallikrein 6 cerebrospinal levels are elevated in multiple sclerosis.
Multiple Sclerosis
ICAM1+ neutrophils promote chronic inflammation via ASPRV1 in B cell-dependent autoimmune encephalomyelitis.
Multiple Sclerosis
Increased protease activity and changes in basic proteins and lipids in multiple sclerosis plaques.
Multiple Sclerosis
Inhibition of SLPI ameliorates disease activity in experimental autoimmune encephalomyelitis.
Multiple Sclerosis
Interferon-gamma regulates cathepsin G activity in microglia-derived lysosomes and controls the proteolytic processing of myelin basic protein in vitro.
Multiple Sclerosis
Kallikrein 6 Regulates Early CNS Demyelination in a Viral Model of Multiple Sclerosis.
Multiple Sclerosis
Latent-period stool proteomic assay of multiple sclerosis model indicates protective capacity of host-expressed protease inhibitors.
Multiple Sclerosis
Peptide Cross-Linked Poly(2-oxazoline) as a Sensor Material for the Detection of Proteases with a Quartz Crystal Microbalance.
Multiple Sclerosis
Pharmacological inhibition of MALT1 protease activity protects mice in a mouse model of multiple sclerosis.
Multiple Sclerosis
Prevention of acute autoimmune encephalomyelitis and abrogation of relapses in murine models of multiple sclerosis by the protease inhibitor D-penicillamine.
Multiple Sclerosis
Protease activated receptor-1 antagonist ameliorates the clinical symptoms of experimental autoimmune encephalomyelitis via inhibiting breakdown of blood-brain barrier.
Multiple Sclerosis
Suppressive effect of camostat mesilate (FOY 305) on acute experimental allergic encephalomyelitis (EAE).
Multiple Sclerosis
The multiple sclerosis degradome: enzymatic cascades in development and progression of central nervous system inflammatory disease.
Multiple Sclerosis
The protease inhibitor, Bowman-Birk Inhibitor, suppresses experimental autoimmune encephalomyelitis: a potential oral therapy for multiple sclerosis.
Multiple Sclerosis
Tissue-type plasminogen activator is a regulator of monocyte diapedesis through the brain endothelial barrier.
Multiple Sclerosis
[Changes in the protease inhibitor activity of the blood serum in patients with disseminated sclerosis]
Multiple System Atrophy
Exploring the putative role of kallikrein-6, calpain-1 and cathepsin-D in the proteolytic degradation of ?-synuclein in multiple system atrophy.
Mumps
AR-12 Inhibits Multiple Chaperones Concomitant With Stimulating Autophagosome Formation Collectively Preventing Virus Replication.
Muscle Cramp
Characterization of a hapten-induced, murine model with multiple features of atopic dermatitis: structural, immunologic, and biochemical changes following single versus multiple oxazolone challenges.
Muscle Cramp
Gut microbiota-CRAMP axis shapes intestinal barrier function and immune responses in dietary gluten-induced enteropathy.
Muscle Cramp
Interplay between antibacterial effectors: a macrophage antimicrobial peptide impairs intracellular Salmonella replication.
Muscle Spasticity
Novel chimeras of botulinum and tetanus neurotoxins yield insights into their distinct sites of neuroparalysis.
Muscle Weakness
Defective mitochondrial protease LonP1 can cause classical mitochondrial disease.
Muscle Weakness
The role of proteases in excitation-contraction coupling failure in muscular dystrophy.
Muscular Atrophy
A novel interplay between irisin and PTH: from basic studies to clinical evidence in hyperparathyroidism.
Muscular Atrophy
A semiautomated measurement of muscle fiber size using the Imaris software.
Muscular Atrophy
Archaeal proteasomes effectively degrade aggregation-prone proteins and reduce cellular toxicities in mammalian cells.
Muscular Atrophy
Clenbuterol suppresses proteasomal and lysosomal proteolysis and atrophy-related genes in denervated rat soleus muscles independently of Akt.
Muscular Atrophy
Conditional activation of MET in differentiated skeletal muscle induces atrophy.
Muscular Atrophy
Daidzein down-regulates ubiquitin-specific protease 19 expression through estrogen receptor ? and increases skeletal muscle mass in young female mice.
Muscular Atrophy
Effects of manipulation of the caspase system on myofibrillar protein degradation in vitro.
Muscular Atrophy
Effects of neuromuscular electrical stimulation on pulmonary alveola and cytokines in chronic obstructive pulmonary disease (COPD) and skeletal muscle atrophy model mice.
Muscular Atrophy
Estrogen administration attenuates immobilization-induced skeletal muscle atrophy in male rats.
Muscular Atrophy
Mitochondrial-targeted antioxidants protect the skeletal muscle against immobilization-induced muscle atrophy.
Muscular Atrophy
Ubiquitin-specific protease 19 blunts pathological cardiac hypertrophy via inhibition of the TAK1-dependent pathway.
Muscular Atrophy, Spinal
Ubiquitin-specific protease 9x deubiquitinates and stabilizes the spinal muscular atrophy protein-survival motor neuron.
Muscular Diseases
Agonist-induced myopathy at the neuromuscular junction is mediated by calcium.
Muscular Diseases
Inducible overexpression of wild-type prion protein in the muscles leads to a primary myopathy in transgenic mice.
Muscular Diseases
Rhabdomyolysis: a case study exploring the possible side effect of lipid lowering medication by a HIV positive patient taking a protease inhibitor.
Muscular Diseases
The N-terminal domain plays a crucial role in the structure of a full-length human mitochondrial Lon protease.
Muscular Diseases
Three-dimensional reconstruction of the S885A mutant of human mitochondrial Lon protease.
Muscular Disorders, Atrophic
Attenuation of skeletal muscle atrophy via protease inhibition.
Muscular Disorders, Atrophic
Bowman Birk inhibitor attenuates dystrophic pathology in mdx mice.
Muscular Dystrophies
A drug inhibits the mitochondrial protease inducing calmitine deficiency in skeletal muscle of patients with Duchenne's muscular dystrophy and dy/dy dystrophic mice.
Muscular Dystrophies
A new pathway encompassing calpain 3 and its newly identified substrate cardiac ankyrin repeat protein is involved in the regulation of the nuclear factor-?B pathway in skeletal muscle.
Muscular Dystrophies
Absence of a calmitine-specific protease inhibitor in skeletal muscle mitochondria of patients with Duchenne's muscular dystrophy.
Muscular Dystrophies
Calpain 3 is activated through autolysis within the active site and lyses sarcomeric and sarcolemmal components.
Muscular Dystrophies
Expression and functional characteristics of calpain 3 isoforms generated through tissue-specific transcriptional and posttranscriptional events.
Muscular Dystrophies
Identification of putative in vivo substrates of calpain 3 by comparative proteomics of overexpressing transgenic and nontransgenic mice.
Muscular Dystrophies
In vivo effects of protease inhibitors on chickens with hereditary muscular dystrophy.
Muscular Dystrophies
Molecular and cellular basis of calpainopathy (limb girdle muscular dystrophy type 2A).
Muscular Dystrophies
Multiple molecular interactions implicate the connectin/titin N2A region as a modulating scaffold for p94/calpain 3 activity in skeletal muscle.
Muscular Dystrophies
Muscular dystrophy: inhibition of degeneration in vivo with protease inhibitors.
Muscular Dystrophies
Non-proteolytic functions of calpain-3 in sarcoplasmic reticulum in skeletal muscles.
Muscular Dystrophies
Null mutation of calpain 3 (p94) in mice causes abnormal sarcomere formation in vivo and in vitro.
Muscular Dystrophies
Proteasome expression in the skeletal muscles of patients with muscular dystrophy.
Muscular Dystrophies
Report of limb girdle muscular dystrophy type 2a in 6 Iranian patients, one with a novel deletion in CAPN3 gene.
Muscular Dystrophies
Successful treatment of murine muscular dystrophy with the protease inhibitor bestatin.
Muscular Dystrophies
Suppressed disassembly of autolyzing p94/CAPN3 by N2A connectin/titin in a genetic reporter system.
Muscular Dystrophies
Therapeutic trial with protease inhibitor (leupeptin) in chicken muscular dystrophy. A histologic and histochemical study.
Muscular Dystrophies
Treatment of mouse muscular dystrophy with the protease inhibitor pepstatin.
Muscular Dystrophies, Limb-Girdle
A new pathway encompassing calpain 3 and its newly identified substrate cardiac ankyrin repeat protein is involved in the regulation of the nuclear factor-?B pathway in skeletal muscle.
Muscular Dystrophies, Limb-Girdle
A proteomic study of calpain-3 and its involvement in limb girdle muscular dystrophy type 2a.
Muscular Dystrophies, Limb-Girdle
A small in-frame deletion within the protease domain of muscle-specific calpain, p94 causes early-onset limb-girdle muscular dystrophy 2A.
Muscular Dystrophies, Limb-Girdle
A third of LGMD2A biopsies have normal calpain 3 proteolytic activity as determined by an in vitro assay.
Muscular Dystrophies, Limb-Girdle
Calpain 3 is activated through autolysis within the active site and lyses sarcomeric and sarcolemmal components.
Muscular Dystrophies, Limb-Girdle
Calpain-3 is autolyzed and hence activated in human skeletal muscle 24 h following a single bout of eccentric exercise.
Muscular Dystrophies, Limb-Girdle
Expression and functional characteristics of calpain 3 isoforms generated through tissue-specific transcriptional and posttranscriptional events.
Muscular Dystrophies, Limb-Girdle
Identification of putative in vivo substrates of calpain 3 by comparative proteomics of overexpressing transgenic and nontransgenic mice.
Muscular Dystrophies, Limb-Girdle
Mdm muscular dystrophy: interactions with calpain 3 and a novel functional role for titin's N2A domain.
Muscular Dystrophies, Limb-Girdle
Molecular and cellular basis of calpainopathy (limb girdle muscular dystrophy type 2A).
Muscular Dystrophies, Limb-Girdle
Molecular diagnosis in LGMD2A: mutation analysis or protein testing?
Muscular Dystrophies, Limb-Girdle
Muscle-specific calpain-3 is phosphorylated in its unique insertion region for enrichment in a myofibril fraction.
Muscular Dystrophies, Limb-Girdle
Non-proteolytic functions of calpain-3 in sarcoplasmic reticulum in skeletal muscles.
Muscular Dystrophies, Limb-Girdle
Null mutation of calpain 3 (p94) in mice causes abnormal sarcomere formation in vivo and in vitro.
Muscular Dystrophies, Limb-Girdle
PLEIAD/SIMC1/C5orf25, a novel autolysis regulator for a skeletal-muscle-specific calpain, CAPN3, scaffolds a CAPN3 substrate, CTBP1.
Muscular Dystrophies, Limb-Girdle
Possible regulation of the conventional calpain system by skeletal muscle-specific calpain, p94/calpain 3.
Muscular Dystrophies, Limb-Girdle
Report of limb girdle muscular dystrophy type 2a in 6 Iranian patients, one with a novel deletion in CAPN3 gene.
Muscular Dystrophies, Limb-Girdle
Stable expression of calpain 3 from a muscle transgene in vivo: immature muscle in transgenic mice suggests a role for calpain 3 in muscle maturation.
Muscular Dystrophies, Limb-Girdle
The N- and C-terminal autolytic fragments of CAPN3/p94/calpain-3 restore proteolytic activity by intermolecular complementation.
Muscular Dystrophy, Duchenne
Cloning of cDNA encoding a regeneration-associated muscle protease whose expression is attenuated in cell lines derived from Duchenne muscular dystrophy patients.
Muscular Dystrophy, Duchenne
Effect of prednisone on protease activities and structural protein levels in rat muscles in vivo.
Musculoskeletal Pain
Circulating Levels of Visceral Adipose Tissue-Derived Serine Protease Inhibitor (Vaspin) Appear as a Marker of Musculoskeletal Pain Disability.
Myalgia
Effects of a protease supplement on eccentric exercise-induced markers of delayed-onset muscle soreness and muscle damage.
Myalgia
The effects of protease supplementation on skeletal muscle function and DOMS following downhill running.
Myasthenia Gravis
Cathepsin V is involved in the degradation of invariant chain in human thymus and is overexpressed in myasthenia gravis.
Myasthenia Gravis
Treatment of experimental autoimmune myasthenia gravis in rabbits with leupeptin, a protease inhibitor.
Mycetoma
Immunogenicity and biophysical properties of a Nocardia brasiliensis protease involved in pathogenesis of mycetoma.
Mycoplasma Infections
Mycoplasma hyorhinis-Contaminated Cell Lines Activate Primary Innate Immune Cells via a Protease-Sensitive Factor.
Mycoses
A non-toxic pokeweed antiviral protein mutant inhibits pathogen infection via a novel salicylic acid-independent pathway.
Mycoses
Antiretroviral drugs saquinavir and ritonavir reduce inhibitory concentration values of itraconazole against Histoplasma capsulatum strains in vitro.
Mycoses
Functional Interaction between Apolipophorins and Complement Regulate the Mosquito Immune Response to Systemic Infections.
Mycoses
Gluten-degrading proteases in wheat infected by Fusarium graminearum - protease identification and effects on gluten and dough properties.
Mycoses
Mucosal and systemic fungal infections in patients with AIDS: prophylaxis and treatment.
Mycoses
Purification and characterization of a neutral serine protease with nematicidal activity from Hirsutella rhossiliensis.
Mycoses
The C3HC type zinc-finger protein (ZFC3) interacting with Lon/MAP1 is important for mitochondrial gene regulation, infection hypha development and longevity of Magnaporthe oryzae.
Mycoses
The Challenge of Potential Drug-Drug Interactions Among People Living With HIV on Antiretroviral Therapy: A Cross-Sectional Study in Selected Provinces in China.
Myelitis
Enterovirus D68 Protease 2Apro Targets TRAF3 To Subvert Host Innate Immune Responses.
Myelodysplastic Syndromes
Indication of an involvement of interleukin-1 beta converting enzyme-like protease in intramedullary apoptotic cell death in the bone marrow of patients with myelodysplastic syndromes.
Myelodysplastic Syndromes
Serine Protease Inhibitor Kunitz-Type 2 Is Downregulated in Myelodysplastic Syndromes and Modulates Cell-Cell Adhesion.
Myelodysplastic Syndromes
Up-regulation of SPINT2/HAI-2 by Azacytidine in bone marrow mesenchymal stromal cells affects leukemic stem cell survival and adhesion.
Myeloproliferative Disorders
Dual functions of cell-autonomous and non-cell-autonomous ADAM10 activity in granulopoiesis.
Myocardial Infarction
39-kD protein inhibits tissue-type plasminogen activator clearance in vivo.
Myocardial Infarction
Acute coronary syndromes in human immunodeficiency virus patients: a meta-analysis investigating adverse event rates and the role of antiretroviral therapy.
Myocardial Infarction
Acute myocardial infarction elevates serine protease activity in saliva of patients with periodontitis.
Myocardial Infarction
Acute Myocardial Infarction in a 34-Year-Old HIV-Positive Female Patient While Undergoing Active Antiretroviral Therapy Containing a Protease Inhibitor.
Myocardial Infarction
Attenuation of increased secretory leukocyte protease inhibitor, matricellular proteins and angiotensin II and left ventricular remodeling by candesartan and omapatrilat during healing after reperfused myocardial infarction.
Myocardial Infarction
Cardiovascular complications and atherosclerotic manifestations in the HIV-infected population: type, incidence and associated risk factors.
Myocardial Infarction
Cardiovascular disease and use of contemporary protease inhibitors: the D:A:D international prospective multicohort study.
Myocardial Infarction
Caspase-dependent and serine protease-dependent DNA fragmentation of myocytes in the ischemia-reperfused rabbit heart: these inhibitors do not reduce infarct size.
Myocardial Infarction
Changes in concentrations of circulating fibroblast activation protein alpha are associated with myocardial damage in patients with acute ST-elevation MI.
Myocardial Infarction
Circulating Serpina3 levels predict the major adverse cardiac events in patients with myocardial infarction.
Myocardial Infarction
Critical role for white blood cell NAD(P)H oxidase-mediated plasminogen activator inhibitor-1 oxidation and ventricular rupture following acute myocardial infarction.
Myocardial Infarction
Dual channel optical tomographic imaging of leukocyte recruitment and protease activity in the healing myocardial infarct.
Myocardial Infarction
Effects of exogenous recombinant APC in mouse models of ischemia reperfusion injury and of atherosclerosis.
Myocardial Infarction
Elastin-like recombinamers-based hydrogel modulates post-ischemic remodeling in a non-transmural myocardial infarction in sheep.
Myocardial Infarction
Enhanced myocardial cathepsin B expression in patients with dilated cardiomyopathy.
Myocardial Infarction
HAART patients can face greater risk of developing heart disease--studies.
Myocardial Infarction
Impact of individual antiretroviral drugs on the risk of myocardial infarction in human immunodeficiency virus-infected patients: a case-control study nested within the French Hospital Database on HIV ANRS cohort CO4.
Myocardial Infarction
Incidence of myocardial infarction in randomized clinical trials of protease inhibitor-based antiretroviral therapy: an analysis of four different protease inhibitors.
Myocardial Infarction
Increased risk of myocardial infarction with duration of protease inhibitor therapy in HIV-infected men.
Myocardial Infarction
Influence of control selection in nested case-control studies: the example of exposure to antiretroviral treatment (ART) and the risk of myocardial infarction (MI) in the French Hospital Database on HIV (FHDH-ANRS CO4).
Myocardial Infarction
LIPID abnormalities in patients infected with human immunodeficiency virus.
Myocardial Infarction
Molecular Implications of Natriuretic Peptides in the Protection from Hypertension and Target Organ Damage Development.
Myocardial Infarction
Mouse Mast Cell Protease 4 Deletion Protects Heart Function and Survival After Permanent Myocardial Infarction.
Myocardial Infarction
Myocardial infarction in HIV-infected men receiving protease inhibitors.
Myocardial Infarction
Near-infrared fluorescent imaging of matrix metalloproteinase activity after myocardial infarction.
Myocardial Infarction
Octahydrocyclopenta[c]pyridine and octahydrocyclopenta[c]pyran analogues as a protease activated receptor 1 (PAR1) antagonist.
Myocardial Infarction
Pentraxin 3, ficolin-2 and lectin pathway associated serine protease MASP-3 as early predictors of myocardial infarction - the HUNT2 study.
Myocardial Infarction
Postprandial lipid effects of low-dose ritonavir vs. raltegravir in HIV-uninfected adults.
Myocardial Infarction
Prospective single-arm observational study of human chymase inhibitor Polygonum hydropiper L in subjects with hypertension.
Myocardial Infarction
Prostate-specific antigen, prostate cancer, and disorders of hemostasis.
Myocardial Infarction
Protease activated receptor 4 (PAR4) antagonists: Research progress on small molecules in the field of antiplatelet agents.
Myocardial Infarction
Protease inhibitors and cardiovascular outcomes in patients with HIV-1.
Myocardial Infarction
Protective anti-inflammatory effect of ADAMTS13 on myocardial ischemia/reperfusion injury in mice.
Myocardial Infarction
Purification and functional characterisation of Rhinocerase, a novel serine protease from the venom of Bitis gabonica rhinoceros.
Myocardial Infarction
Redox Regulation of Neutrophils and Monocytes in Different Types of Myocardial Infarction.
Myocardial Infarction
Role of PMN elastase on ischemic myocardial injury in evolving myocardial infarction: correlation with clinical parameters and intervention by protease inhibitor ulinastatin.
Myocardial Infarction
Soluble expression of active recombinant human tissue plasminogen activator derivative (K2S) in Escherichia coli.
Myocardial Infarction
Structural basis of specific inhibition of tissue-type plasminogen activator by plasminogen activators inhibitor-1.
Myocardial Infarction
Synthesis and evaluation of novel and potent protease activated receptor 4 (PAR4) antagonists based on a quinazolin-4(3H)-one scaffold.
Myocardial Infarction
TFPI inhibits lectin pathway of complement activation by direct interaction with MASP-2.
Myocardial Infarction
Tissue factor, protease activated receptors and pathologic heart remodelling.
Myocardial Infarction
Trans-fused 5-[(tert-Butoxtycarbonyl)amino]octahydroindenes as a protease activated receptor-1 (PAR1) antagonist.
Myocardial Infarction
Viral load of the human immunodeficiency virus could be an independent risk factor for endothelial dysfunction.
Myocardial Infarction
[ACTION OF PROTEASE INHIBITORS IN THE SYNDROME DUE TO MYOCARDIAL INFARCT.]
Myocardial Infarction
[Acute myocardial infarct in HIV-positive patients in treatment with protease inhibitors]
Myocardial Infarction
[Effect of drugs on the permeability of the histohematic barriers in a complicated course of myocardial infarct]
Myocardial Infarction
[Effect of protease inhibitors on indices of microcirculation and the blood kinin system in myocardial infarct patients]
Myocardial Infarction
[Myocardial infarction in hiv patients treated with protease inhibitors: report of two cases]
Myocardial Infarction
[Myocardial infarction in the course of antiretroviral therapy with protease inhibitor]
Myocardial Infarction
[Protease inhibitors in the combined treatment of acute myocardial infarct]
Myocardial Infarction
[Rationale for using kinin system inhibitors in patients with acute ischemia and infarction of the myocardium during the prehospital phase]
Myocardial Infarction
[Relationship between post-stenting coronary thrombolysis in myocardial infarction flow and plasma von Willebrand factor and ADAMTS-13 levels in patients with ST segment elevation myocardial infarction].
Myocardial Infarction
[The effect of protease inhibitions on the serum proteolytic activity in the myocardial infarct syndrome]
Myocardial Infarction
[Use of natural kallikrein-protease inhibitors (contrical and gordox) in the therapy of acute myocardial infarct]
Myocardial Ischemia
Apoptotic Protease Activating Factor-1 Inhibitor Mitigates Myocardial Ischemia Injury via Disturbing Procaspase-9 Recruitment by Apaf-1.
Myocardial Ischemia
Cardioprotection by a novel recombinant serine protease inhibitor in myocardial ischemia and reperfusion injury.
Myocardial Ischemia
Cardioprotective effects of the serine protease inhibitor aprotinin after regional ischemia and reperfusion on the beating heart.
Myocardial Ischemia
Diagnosis of silent myocardial ischemia during the staging of HIV-associated lymphoma with FDG PET/CT.
Myocardial Ischemia
Effect of NCO-700, an inhibitor of protease, on myocardial pH decreased by coronary occlusion in dogs.
Myocardial Ischemia
Inhibition of granulocyte-derived proteases reduces the increase in plasma endothelin associated with myocardial ischemia in the pig.
Myocardial Ischemia
Overexpression and pre-treatment of recombinant human Secretory Leukocyte Protease Inhibitor (rhSLPI) reduces an in vitro ischemia/reperfusion injury in rat cardiac myoblast (H9c2) cell.
Myocardial Ischemia
Preservation of myocardial integrity by a protease inhibitor during acute myocardial ischemia.
Myocardial Ischemia
Serine protease inhibitor nafamostat given before reperfusion reduces inflammatory myocardial injury by complement and neutrophil inhibition.
Myocardial Ischemia
Two-dimensional analysis of myocardial protein expression following myocardial ischemia and reperfusion in rabbits.
Myocardial Reperfusion Injury
Cardioprotective effects of the serine protease inhibitor aprotinin after regional ischemia and reperfusion on the beating heart.
Myocardial Stunning
A protease inhibitor, NCO-700, improves the contractile function in stunned canine myocardium.
Myocardial Stunning
Inhomogeneous disappearance of myofilament-related cytoskeletal proteins in stunned myocardium of guinea pig.
Myocardial Stunning
Intrinsic myofilament alterations underlying the decreased contractility of stunned myocardium. A consequence of Ca2+-dependent proteolysis?
Myocardial Stunning
Protease inhibitor leupeptin attenuates myocardial stunning in rat heart.
Myocardial Stunning
Protective effect of the protease inhibitor leupeptin against myocardial stunning.
Myocarditis
Inhibition of Coxsackievirus-associated dystrophin cleavage prevents cardiomyopathy.
Myocarditis
Proteasomal Protein Degradation: Adaptation of Cellular Proteolysis With Impact on Virus-and Cytokine-Mediated Damage of Heart Tissue During Myocarditis.
Myocarditis
The Role of Protease-Activated Receptors for the Development of Myocarditis: Possible Therapeutic Implications.
Myocarditis
[Serum concentrations of proteinase inhibitors, complement components and of acid alpha-1-glucoprotein in children with myocarditis (author's transl)]
Myoclonic Epilepsies, Progressive
A pathogenetic hypothesis of Unverricht-Lundborg disease onset and progression.
Myoclonic Epilepsies, Progressive
Characterization of PTZ-induced seizure susceptibility in a down syndrome mouse model that overexpresses CSTB.
Myoclonic Epilepsies, Progressive
The epilepsy, the protease inhibitor and the dodecamer: progressive myoclonus epilepsy, cystatin b and a 12-mer repeat expansion.
Myoepithelioma
Adhesion and protease activity in cell lines from human salivary gland tumors are regulated by the laminin-derived peptide AG73, syndecan-1 and beta1 integrin.
Myoma
Human uterus myoma and gene expression profiling: A novel in vitro model for studying secretory leukocyte protease inhibitor-mediated tumor invasion.
Myoma
[Diagnostic value of determining alpha1 protease inhibitor and alpha2 macroglobulin in the serum of women with malignant and non-malignant ovarian tumors and uterine myomas]
Myopia
Cause and Effect Relationship between Changes in Scleral Matrix Metallopeptidase-2 Expression and Myopia Development in Mice.
Myopia
Müller glia-derived PRSS56 is required to sustain ocular axial growth and prevent refractive error.
Myositis
Antigen processing and presentation in human muscle: cathepsin S is critical for MHC class II expression and upregulated in inflammatory myopathies.
Myositis
beta-Amyloid precursor protein mRNA is increased in inclusion-body myositis muscle.
Myositis
Protease nexin I expression is up-regulated in human skeletal muscle by injury-related factors.
Myositis, Inclusion Body
beta-Amyloid precursor protein mRNA is increased in inclusion-body myositis muscle.
Myotonic Dystrophy
Leukocyte protease activities in myotonic dystrophy: studies on effects of protease inhibitors.
Myxoma
Adeno-Associated Virus Delivery of Viral Serpins for Ocular Diseases: Design and Validation.
Myxoma
Amelioration of antigen induced arthritis in rabbits treated with a secreted viral serine proteinase inhibitor.
Myxoma
Myxoma viral serpin, Serp-1, inhibits human monocyte adhesion through regulation of actin-binding protein filamin B.
Myxoma
Myxoma virus and malignant rabbit fibroma virus encode a serpin-like protein important for virus virulence.
Myxoma
Potential for broad-spectrum protection against feline calicivirus using an attenuated myxoma virus expressing a chimeric FCV capsid protein.
Myxoma
Serine protease inhibitor Serp-1 strongly impairs atherosclerotic lesion formation and induces a stable plaque phenotype in ApoE-/-mice.
Nairobi Sheep Disease
Crimean-Congo hemorrhagic fever virus genome L RNA segment and encoded protein.
Nasal Polyps
Airborne Fungi Induce Nasal Polyp Epithelial Cell Activation and Toll-Like Receptor Expression.
Nasal Polyps
Dexamethasone-induced apoptosis of freshly isolated human nasal epithelial cells concomitant with abrogation of IL-8 production.
Nasal Polyps
Growth and differentiation of human nasal epithelial cells in culture. Serum-free, hormone-supplemented medium and proteoglycan synthesis.
Nasal Polyps
Safety-assessment of 3-methoxyquercetin as an antirhinoviral compound for nasal application: effect on ciliary beat frequency.
Nasal Polyps
Tissue and Exosomal Serine Protease Inhibitors Are Significantly Overexpressed in Chronic Rhinosinusitis With Nasal Polyps.
Nasopharyngeal Carcinoma
CEBPB knockdown sensitizes nasopharyngeal carcinoma cells to cisplatin by promoting the expression of serine protease inhibitor Kazal-type 5.
Nasopharyngeal Carcinoma
Expressions of Tumor Necrosis Factor alpha-induced Protein 3 and Mammary Serine Protease Inhibitor in Radiotherapy of Nasopharyngeal Carcinoma.
Nasopharyngeal Carcinoma
Extracellular protease ADAMTS9 suppresses esophageal and nasopharyngeal carcinoma tumor formation by inhibiting angiogenesis.
Nasopharyngeal Carcinoma
Knockdown of TMPRSS3, a Transmembrane Serine Protease, Inhibits the Proliferation, Migration, and Invasion in Human Nasopharyngeal Carcinoma Cells.
Nasopharyngeal Carcinoma
ShRNA-mediated silencing of the ubiquitin-specific protease 22 gene restrained cell progression and affected the Akt pathway in nasopharyngeal carcinoma.
Nasopharyngeal Carcinoma
SPINK6 Promotes Metastasis of Nasopharyngeal Carcinoma via Binding and Activation of Epithelial Growth Factor Receptor.
Nasopharyngeal Carcinoma
The relationship between secretory leukocyte protease inhibitor expression and Epstein-Barr virus status among patients with nasopharyngeal carcinoma.
Nasopharyngeal Carcinoma
[The role of EPR-1 in proliferation and apoptosis in nasopharyngeal carcinoma]
Nematode Infections
An efficient gene disruption system for the nematophagous fungus Purpureocillium lavendulum.
Nematode Infections
Biotechnological advances with applicability in potatoes for resistance against root-knot nematodes.
Nematode Infections
Constitutive expression of mouse mast cell protease-1 in normal BALB/c mice and its up-regulation during intestinal nematode infection.
Nematode Infections
Differential expression of genes in fetal brain as a consequence of maternal protein deficiency and nematode infection.
Nematode Infections
Genotype-dependent expression of specific members of potato protease inhibitor gene families in different tissues and in response to wounding and nematode infection.
Nematode Infections
IgE-mediated release of rat mast cell protease II, beta-hexosaminidase and leukotriene C4 from cultured bone marrow-derived rat mast cells.
Nematode Infections
Physicochemical properties of the modeled structure of astacin metalloprotease moulting enzyme NAS-36 and mapping the druggable allosteric space of Heamonchus contortus, Brugia malayi and Ceanorhabditis elegans via molecular dynamics simulation.
Nematode Infections
Protease activity and phytocystatin expression in Arabidopsis thaliana upon Heterodera schachtii infection.
Neoplasm Metastasis
'Increased expression of seprase, a membrane-type serine protease, is associated with lymph node metastasis in human colorectal cancer'.
Neoplasm Metastasis
(4-aminomethyl)phenylguanidine derivatives as nonpeptidic highly selective inhibitors of human urokinase.
Neoplasm Metastasis
2, 3-Dihydro-3?-methoxy Withaferin-A Lacks Anti-Metastasis Potency: Bioinformatics and Experimental Evidences.
Neoplasm Metastasis
6-Substituted Hexamethylene Amiloride (HMA) Derivatives as Potent and Selective Inhibitors of the Human Urokinase Plasminogen Activator for Use in Cancer.
Neoplasm Metastasis
A comparative study of protein expression in primary colorectal cancer and synchronous hepatic metastases: the significance of matrix metalloproteinase-1 expression as a predictor of liver metastasis.
Neoplasm Metastasis
A JUN N-terminal kinase inhibitor induces ectodomain shedding of the cancer-associated membrane protease Prss14/epithin via protein kinase C?II.
Neoplasm Metastasis
A Kunitz-type protease inhibitor, bikunin, inhibits ovarian cancer cell invasion by blocking the calcium-dependent transforming growth factor-beta 1 signaling cascade.
Neoplasm Metastasis
A multifunctional protease inhibitor to regulate endolysosomal function.
Neoplasm Metastasis
A Novel Antitumor Prodrug Platform Designed to Be Cleaved by the Endoprotease Legumain.
Neoplasm Metastasis
A novel role of interleukin-13 receptor alpha2 in pancreatic cancer invasion and metastasis.
Neoplasm Metastasis
A novel strategy for the tumor angiogenesis-targeted gene therapy: generation of angiostatin from endogenous plasminogen by protease gene transfer.
Neoplasm Metastasis
A novel transmembrane serine protease (TMPRSS3) overexpressed in pancreatic cancer.
Neoplasm Metastasis
A role for membrane-type serine protease (MT-SP1) in intestinal epithelial turnover.
Neoplasm Metastasis
A role for tissue factor in cell adhesion and migration mediated by interaction with actin-binding protein 280.
Neoplasm Metastasis
A soybean Kunitz trypsin inhibitor suppresses ovarian cancer cell invasion by blocking urokinase upregulation.
Neoplasm Metastasis
Activation mechanisms of the urokinase-type plasminogen activator promoter by hepatocyte growth factor/scatter factor.
Neoplasm Metastasis
Activation of matrix metalloproteinase-2 (MMP-2) by membrane type 1 matrix metalloproteinase through an artificial receptor for proMMP-2 generates active MMP-2.
Neoplasm Metastasis
Activity Regulation by Fibrinogen and Fibrin of Streptokinase from Streptococcus Pyogenes.
Neoplasm Metastasis
ADAM-12 as a Diagnostic Marker for the Proliferation, Migration and Invasion in Patients with Small Cell Lung Cancer.
Neoplasm Metastasis
ADAM-17 over-expression in gallbladder carcinoma correlates with poor prognosis of patients.
Neoplasm Metastasis
ADAMTS1 Promotes Adhesion to Extracellular Matrix Proteins and Predicts Prognosis in Early Stage Breast Cancer Patients.
Neoplasm Metastasis
Adenovirus E1A represses protease gene expression and inhibits metastasis of human tumor cells.
Neoplasm Metastasis
alpha2-Macroglobulin is mainly produced by cancer cells and not by hepatocytes in rats with colon carcinoma metastases in liver.
Neoplasm Metastasis
Amplification of chromosome 21q22.3 harboring trefoil factor family genes in liver fluke related cholangiocarcinoma is associated with poor prognosis.
Neoplasm Metastasis
Amplification of the Urokinase-Type Plasminogen Activator Receptor (uPAR) Gene in Ductal Pancreatic Carcinomas Identifies a Clinically High-Risk Group.
Neoplasm Metastasis
Anchored protease-activatable polymersomes for molecular diagnostics of metastatic cancer cells.
Neoplasm Metastasis
Androgen-Induced TMPRSS2 Activates Matriptase and Promotes Extracellular Matrix Degradation, Prostate Cancer Cell Invasion, Tumor Growth, and Metastasis.
Neoplasm Metastasis
Anti-tumour/metastasis effects of the potassium-sparing diuretic amiloride: An orally active anti-cancer drug waiting for its call-of-duty?
Neoplasm Metastasis
Antimetastasis Effect of Anthraquinones from Marine Fungus, Microsporum sp.
Neoplasm Metastasis
Antithrombin controls tumor migration, invasion and angiogenesis by inhibition of enteropeptidase.
Neoplasm Metastasis
Antitumor effects of Mucin 1/sec involves the modulation of urokinase-type plasminogen activator and signal transducer and activator of transcription 1 expression in tumor cells.
Neoplasm Metastasis
Assessment of the interaction between urokinase and reactive site mutants of protein C inhibitor.
Neoplasm Metastasis
Association of trypsin expression with tumour progression and matrilysin expression in human colorectal cancer.
Neoplasm Metastasis
ATP-dependent Lon protease controls tumor bioenergetics by reprogramming mitochondrial activity.
Neoplasm Metastasis
Autoactivation and calpain-1-mediated shedding of hepsin in human hepatoma cells.
Neoplasm Metastasis
Bikunin target genes in ovarian cancer cells identified by microarray analysis.
Neoplasm Metastasis
Biochemical characterization of human tissue kallikrein 15 and examination of its potential role in cancer.
Neoplasm Metastasis
Bioconjugatable azo-based dark-quencher dyes: synthesis and application to protease-activatable far-red fluorescent probes.
Neoplasm Metastasis
Biological and clinical significance of cathepsin D in breast cancer metastasis.
Neoplasm Metastasis
Bromelain proteases suppress growth, invasion and lung metastasis of B16F10 mouse melanoma cells.
Neoplasm Metastasis
C/EBP?/AEP Signaling Regulates the Oxidative Stress in Malignant Cancers, Stimulating the Metastasis.
Neoplasm Metastasis
Cardamonin inhibited cell viability and tumorigenesis partially through blockade of testes-specific protease 50-mediated nuclear factor-kappaB signaling pathway activation.
Neoplasm Metastasis
Caspase-3 enhances lung metastasis and cell migration in a protease-independent mechanism through the ERK pathway.
Neoplasm Metastasis
Caspase-8 association with the focal adhesion complex promotes tumor cell migration and metastasis.
Neoplasm Metastasis
Cathepsin C promotes breast cancer lung metastasis by modulating neutrophil infiltration and neutrophil extracellular trap formation.
Neoplasm Metastasis
Cathepsin D maturation and its stimulatory effect on metastasis are prevented by addition of KDEL retention signal.
Neoplasm Metastasis
Cathepsin D specifically cleaves the chemokines macrophage inflammatory protein-1 alpha, macrophage inflammatory protein-1 beta, and SLC that are expressed in human breast cancer.
Neoplasm Metastasis
Cathepsin D, both a prognostic factor and a predictive factor for the effect of adjuvant tamoxifen in breast cancer. South Sweden Breast Cancer Group.
Neoplasm Metastasis
Cathepsin D: newly discovered functions of a long-standing aspartic protease in cancer and apoptosis.
Neoplasm Metastasis
CD163 as a marker of M2 macrophage, contribute to predicte aggressiveness and prognosis of Kazakh esophageal squamous cell carcinoma.
Neoplasm Metastasis
CD26/DPPIV expression and 8-azaguanine response in T-acute lymphoblastic leukaemia cell lines in culture.
Neoplasm Metastasis
Changes in plasma levels of protease inhibitors to the degree of metastasis and prognosis of gastric cancer.
Neoplasm Metastasis
Characterization and enumeration of cells secreting tumor markers in the peripheral blood of breast cancer patients.
Neoplasm Metastasis
Characterization of downstream Ras signals that induce alternative protease-dependent invasive phenotypes.
Neoplasm Metastasis
Characterization of F3II, a sarcomatoid mammary carcinoma cell line originated from a clonal subpopulation of a mouse adenocarcinoma.
Neoplasm Metastasis
Chemical Modulation of Human Mitochondrial ClpP: Potential Application in Cancer Therapeutics.
Neoplasm Metastasis
Circulating nucleic acids and protease activities in blood of tumor patients.
Neoplasm Metastasis
Clinical evidence for correlation of insufficient tissue oxygen supply (hypoxia) and tumor-associated proteolysis in squamous cell carcinoma of the head and neck.
Neoplasm Metastasis
Clinical impact of the plasminogen activation system in tumor invasion and metastasis: prognostic relevance and target for therapy.
Neoplasm Metastasis
Cloning of a new Kunitz-type protease inhibitor with a putative transmembrane domain overexpressed in pancreatic cancer.
Neoplasm Metastasis
Combined evaluation of urokinase-type plasminogen activator and plasminogen activator inhibitor-2 expression in gastric carcinoma.
Neoplasm Metastasis
Coronin 1C promotes triple-negative breast cancer invasiveness through regulation of MT1-MMP traffic and invadopodia function.
Neoplasm Metastasis
Correction for: Ubiquitin-specific protease 4 promotes metastasis of hepatocellular carcinoma by increasing TGF-? signaling-induced epithelial-mesenchymal transition.
Neoplasm Metastasis
Correction: Protease Nexin I is a feedback regulator of EGF/ PKC/MAPK/EGR1 signaling in breast cancer cells metastasis and stemness.
Neoplasm Metastasis
Correlation of the osteoblastic phenotype with prostate-specific antigen expression in metastatic prostate cancer: implications for paracrine growth.
Neoplasm Metastasis
Crosstalk between cancer and haemostasis. Implications for cancer biology and cancer-associated thrombosis with focus on tissue factor.
Neoplasm Metastasis
Crystals of the urokinase type plasminogen activator variant beta(c)-uPAin complex with small molecule inhibitors open the way towards structure-based drug design.
Neoplasm Metastasis
Curcumin-targeting Pericellular Serine Protease Matriptase Role in Suppression of Prostate Cancer Cell Invasion, Tumor Growth and Metastasis.
Neoplasm Metastasis
Cytoplasmic and nuclear maspin expression in lung carcinomas: an immunohistochemical study using tissue microarrays.
Neoplasm Metastasis
Decreased secretion of Cathepsin D in breast cancer in vivo by tamoxifen: mediated by the mannose-6-phosphate/IGF-II receptor?
Neoplasm Metastasis
Delivery of a Protease-Activated Cytolytic Peptide Prodrug by Perfluorocarbon Nanoparticles.
Neoplasm Metastasis
Deoxyribonuclease treatment prevents blood-borne liver metastasis of cutaneously transplanted tumour cells in mice.
Neoplasm Metastasis
Design, synthesis, and biological evaluation of a dual tumor-specific motive containing integrin-targeted plasmin-cleavable doxorubicin prodrug.
Neoplasm Metastasis
Design, Synthesis, and Testing of Potent, Selective Hepsin Inhibitors via Application of an Automated Closed-Loop Optimization Platform.
Neoplasm Metastasis
Design, synthesis, biochemical studies, cellular characterization, and structure-based computational studies of small molecules targeting the urokinase receptor.
Neoplasm Metastasis
Detection of Cancer-Specific Proteases Using Magnetic Relaxation of Peptide-Conjugated Nanoparticles in Biological Environment.
Neoplasm Metastasis
Development of a Protease Biosensor Based on a Dimerization-Dependent Red Fluorescent Protein.
Neoplasm Metastasis
Differences in the Inhibitory Specificity Distinguish the Efficacy of Plant Protease Inhibitors on Mouse Fibrosarcoma.
Neoplasm Metastasis
Different roles for plasminogen activators and metalloproteinases in melanoma metastasis.
Neoplasm Metastasis
Differential activity of cathepsin L in human placenta at two different stages of gestation.
Neoplasm Metastasis
Differential expression of protease activity in serum samples of prostate carcinoma patients with metastases.
Neoplasm Metastasis
Differential inhibition of endothelial cell proliferation and migration by urokinase subdomains: amino-terminal fragment and kringle domain.
Neoplasm Metastasis
Dipeptidyl peptidase IV expression in cancer and stromal cells of human esophageal squamous cell carcinomas, adenocarcinomas and squamous cell carcinoma cell lines.
Neoplasm Metastasis
Direct visualization of protease activity on cells migrating in three-dimensions.
Neoplasm Metastasis
Distinct encounter complexes of PAI-1 with plasminogen activators and vitronectin revealed by changes in the conformation and dynamics of the reactive center loop.
Neoplasm Metastasis
Diverse functions of protease receptor tissue factor in inflammation and metastasis.
Neoplasm Metastasis
DNA methylation signal has a major role in the response of human breast cancer cells to the microenvironment.
Neoplasm Metastasis
Down-regulation of cathepsin-D expression by antisense gene transfer inhibits tumor growth and experimental lung metastasis of human breast cancer cells.
Neoplasm Metastasis
Downregulation of ubiquitin-specific protease 14 (USP14) inhibits breast cancer cell proliferation and metastasis, but promotes apoptosis.
Neoplasm Metastasis
Drug-resistant human laryngeal carcinoma cells have increased levels of cathepsin B.
Neoplasm Metastasis
E-Cadherin fragments as potential mediators for peritoneal metastasis in advanced epithelial ovarian cancer.
Neoplasm Metastasis
Effect of LY287045, a thrombin/trypsin inhibitor, on thrombin and trypsin-induced aortic contraction and relaxation.
Neoplasm Metastasis
Effect of Silibinin on Maspin and ER? Gene Expression in MCF-7 Human Breast Cancer Cell Line.
Neoplasm Metastasis
Effective inhibition of experimental metastasis and prolongation of survival in mice by a potent factor Xa-specific synthetic serine protease inhibitor with weak anticoagulant activity.
Neoplasm Metastasis
Effects of cathepsin D inhibitor from Vicia sativa L. seed hulls on human skin fibroblasts and breast cancer cells (in vitro studies).
Neoplasm Metastasis
Effects of demethylating agent 5-aza-2(')-deoxycytidine and histone deacetylase inhibitor FR901228 on maspin gene expression in oral cancer cell lines.
Neoplasm Metastasis
Effects of serine protease and deoxyribonuclease on intravascular tumor cell arrest in rat blood-borne lung metastasis.
Neoplasm Metastasis
Effects of vitamin A and dexamethasone on collagen degradation in mouse mammary adenocarcinoma.
Neoplasm Metastasis
Electrochemical sensing of human neutrophil elastase and polymorphonuclear neutrophil activity.
Neoplasm Metastasis
Elevated expression of USP22 in correlation with poor prognosis in patients with invasive breast cancer.
Neoplasm Metastasis
Enhanced activity of meprin-?, a pro-migratory and pro-angiogenic protease, in colorectal cancer.
Neoplasm Metastasis
Epigenetic silencing of PRSS3 provides growth and metastasis advantage for human hepatocellular carcinoma.
Neoplasm Metastasis
Expression analysis of maspin in invasive ductal carcinoma of breast and modulation of its expression by curcumin in breast cancer cell lines.
Neoplasm Metastasis
Expression and activity analysis of a new fusion protein targeting ovarian cancer cells.
Neoplasm Metastasis
Expression and regulation of tumor suppressor gene maspin in human bladder cancer.
Neoplasm Metastasis
Expression levels of seprase/FAP? and DPPIV/CD26 in epithelial ovarian carcinoma.
Neoplasm Metastasis
Expression of A disintegrin and metalloprotease 10 in pancreatic carcinoma.
Neoplasm Metastasis
Expression of ADAMs (a disintegrin and metalloproteases) and TIMP-3 (tissue inhibitor of metalloproteinase-3) in human prostatic adenocarcinomas.
Neoplasm Metastasis
Expression of cathepsin D, stromelysin-3, and urokinase by reactive stromal cells on breast carcinoma prognosis.
Neoplasm Metastasis
Expression of Maspin in non-muscle invasive bladder carcinoma: correlation with tumor angiogenesis and prognosis.
Neoplasm Metastasis
Expression of maspin in non-small cell lung cancer and its relationship to vasculogenic mimicry.
Neoplasm Metastasis
Expression of maspin in non-small-cell lung cancer: correlation with clinical features.
Neoplasm Metastasis
Expression of p16 in lymph node metastases of adjuvantly treated stage III colorectal cancer patients identifies poor prognostic subgroups: a retrospective analysis of biomarkers in matched primary tumor and lymph node metastases.
Neoplasm Metastasis
Expression of protease activated receptor-2 in human colorectal cancer and its association with tumor progression.
Neoplasm Metastasis
Expression of secretory leukocyte protease inhibitor detected by immunohistochemistry correlating with prognosis and metastasis in colorectal cancer.
Neoplasm Metastasis
Expression of serine protease SNC19/matriptase and its inhibitor hepatocyte growth factor activator inhibitor type 1 in normal and malignant tissues of gastrointestinal tract.
Neoplasm Metastasis
Expression of the immune modulator secretory leukocyte protease inhibitor (SLPI) in colorectal cancer liver metastases and matched primary tumors is associated with a poorer prognosis.
Neoplasm Metastasis
Expression of the tumor suppressor gene maspin and its significance in intraductal papillary mucinous neoplasms of the pancreas.
Neoplasm Metastasis
Expression of Tissue Factor Pathway Inhibitor 2 in Human Pancreatic Carcinoma and its Effect on Tumor Growth, Invasion, and Migration in vitro and in vivo.
Neoplasm Metastasis
Expression of TMPRSS4 in non-small cell lung cancer and its modulation by hypoxia.
Neoplasm Metastasis
Fibrin formation induced by tumor procoagulants enhances urokinase activity produced by mammary carcinoma cells.
Neoplasm Metastasis
Fibroblasts transformed by different ras oncogenes show dissimilar patterns of protease gene expression and regulation.
Neoplasm Metastasis
Fragments generated upon extracellular matrix remodeling: Biological regulators and potential drugs.
Neoplasm Metastasis
Gene expression profiles in cells transformed by overexpression of the IGF-I receptor.
Neoplasm Metastasis
Genistein inhibits human prostate cancer cell detachment, invasion, and metastasis.
Neoplasm Metastasis
Gossypol Reduces Metastasis and Epithelial-Mesenchymal Transition by Targeting Protease in Human Cervical Cancer.
Neoplasm Metastasis
HAI-2 as a novel inhibitor of plasmin represses lung cancer cell invasion and metastasis.
Neoplasm Metastasis
Hepatocyte growth factor activation inhibitors (HAI-1 and HAI-2) regulate HGF-induced invasion of human breast cancer cells.
Neoplasm Metastasis
Heregulin inhibits proliferation via ERKs and phosphatidyl-inositol 3-kinase activation but regulates urokinase plasminogen activator independently of these pathways in metastatic mammary tumor cells.
Neoplasm Metastasis
High frequency of coexpression of maspin with p63 and p53 in squamous cell carcinoma but not in adenocarcinoma of the lung.
Neoplasm Metastasis
High level synthesis of recombinant soluble urokinase receptor (CD87) by ovarian cancer cells reduces intraperitoneal tumor growth and spread in nude mice.
Neoplasm Metastasis
High levels of cathepsin B predict poor outcome in patients with breast cancer.
Neoplasm Metastasis
Hispolon suppresses metastasis via autophagic degradation of cathepsin S in cervical cancer cells.
Neoplasm Metastasis
Human monocyte chemotactic protein-3 (MCP-3): molecular cloning of the cDNA and comparison with other chemokines.
Neoplasm Metastasis
Identification of degradome components associated with prostate cancer progression by expression analysis of human prostatic tissues.
Neoplasm Metastasis
Identification of inhibitory scFv antibodies targeting fibroblast activation protein utilizing phage display functional screens.
Neoplasm Metastasis
IL-4 induces cathepsin protease activity in tumor-associated macrophages to promote cancer growth and invasion.
Neoplasm Metastasis
Immunohistochemical analysis and prognostic value of cathepsin D determination in laryngeal squamous cell carcinoma.
Neoplasm Metastasis
Immunohistochemical visualisation of cathepsin-D expression in breast cancer.
Neoplasm Metastasis
Improved detection of ovarian cancer metastases by intraoperative quantitative fluorescence protease imaging in a pre-clinical model.
Neoplasm Metastasis
In vivo imaging of membrane type-1 matrix metalloproteinase with a novel activatable near-infrared fluorescence probe.
Neoplasm Metastasis
Increased expression of seprase, a membrane-type serine protease, is associated with lymph node metastasis in human colorectal cancer.
Neoplasm Metastasis
Increased plasma cathepsin D concentration in hepatic carcinoma and cirrhosis but not in breast cancer.
Neoplasm Metastasis
Increased plasma levels of serine proteinase inhibitors in lung cancer patients.
Neoplasm Metastasis
Increased von Willebrand factor over decreased ADAMTS-13 activity is associated with poor prognosis in patients with advanced non-small-cell lung cancer.
Neoplasm Metastasis
Influence of HPV16 E2 and its localisation on the expression of matrix metalloproteinase-9.
Neoplasm Metastasis
Inhibition of experimental blood-borne lung metastasis by protease inhibitors.
Neoplasm Metastasis
Inhibition of experimental metastasis by enzyme inhibitors from microorganisms and plants.
Neoplasm Metastasis
Inhibition of hepatocellular carcinoma invasion by suppression of claudin-10 in HLE cells.
Neoplasm Metastasis
Inhibition of LONP1 Suppresses Pancreatic Cancer Progression Via c-Jun N-Terminal Kinase Pathway-Meditated Epithelial-Mesenchymal Transition.
Neoplasm Metastasis
Inhibition of the interaction of urokinase-type plasminogen activator (uPA) with its receptor (uPAR) by synthetic peptides.
Neoplasm Metastasis
Inhibition of TMPRSS2 by HAI-2 reduces prostate cancer cell invasion and metastasis.
Neoplasm Metastasis
Inhibition of TMPRSS4 mediated epithelial-mesenchymal transition is critically involved in antimetastatic effect of melatonin in colorectal cancers.
Neoplasm Metastasis
Inhibitory effect of a serine protease inhibitor, FOY-305 on the invasion and metastasis of human pancreatic cancers.
Neoplasm Metastasis
Inhibitory effect of lignin from Canna edulis Ker residues on trypsin: kinetics and molecular docking studies.
Neoplasm Metastasis
Inhibitory effect of nafamostat mesilate on metastasis into the livers of mice and on invasion of the extracellular matrix by cancer cells.
Neoplasm Metastasis
Integrated functions of membrane-type 1 matrix metalloproteinase in regulating cancer malignancy: Beyond a proteinase.
Neoplasm Metastasis
Involvement of plasminogen activator production with tumor metastasis in a rat model.
Neoplasm Metastasis
ITIH5, a novel member of the inter-alpha-trypsin inhibitor heavy chain family is downregulated in breast cancer.
Neoplasm Metastasis
Knocking down USP39 Inhibits the Growth and Metastasis of Non-Small-Cell Lung Cancer Cells through Activating the p53 Pathway.
Neoplasm Metastasis
Kondrat'eva ligation: Diels-Alder-based irreversible reaction for bioconjugation.
Neoplasm Metastasis
Leading the invasion: The role of Cathepsin S in the tumour microenvironment.
Neoplasm Metastasis
Levels of uPA and PAI-1 in breast cancer and its correlation to Ki67-index and results of a 21-multigene-array.
Neoplasm Metastasis
LIM kinase 1 increases tumor metastasis of human breast cancer cells via regulation of the urokinase-type plasminogen activator system.
Neoplasm Metastasis
LonP1 Differently Modulates Mitochondrial Function and Bioenergetics of Primary Versus Metastatic Colon Cancer Cells.
Neoplasm Metastasis
Loss of Maspin Expression in Bladder Cancer: Its Relationship with p53 and Clinicopathological Parameters.
Neoplasm Metastasis
Loss of Maspin expression is a negative prognostic factor in common salivary gland tumors.
Neoplasm Metastasis
Low levels of urokinase plasminogen activator components in basal cell carcinoma of the skin.
Neoplasm Metastasis
Lysosome-Targeting Fluorogenic Probe for Cathepsin B Imaging in Living Cells.
Neoplasm Metastasis
Macrophage Elastase Induces TRAIL-mediated Tumor Cell Death Through its Carboxyterminal Domain.
Neoplasm Metastasis
Magnetic nanoparticle decorated anodic alumina nanotubes for fluorescent detection of cathepsin B.
Neoplasm Metastasis
MALT1 is a critical mediator of PAR1-driven NF-?B activation and metastasis in multiple tumor types.
Neoplasm Metastasis
Mammary serine protease inhibitor inhibits epithelial growth factor-induced epithelial-mesenchymal transition of esophageal carcinoma cells.
Neoplasm Metastasis
Maspin acts at the cell membrane to inhibit invasion and motility of mammary and prostatic cancer cells.
Neoplasm Metastasis
Maspin and Mutant p53 expression in malignant melanoma and carcinoma: use of tissue microarray.
Neoplasm Metastasis
Maspin expression in epithelial skin tumours: an immunohistochemical study.
Neoplasm Metastasis
Maspin expression was involved in colorectal adenoma-adenocarcinoma sequence and liver metastasis of tumors.
Neoplasm Metastasis
Maspin functions as tumor suppressor by increasing cell adhesion to extracellular matrix in prostate tumor cells.
Neoplasm Metastasis
Maspin inhibits cell migration in the absence of protease inhibitory activity.
Neoplasm Metastasis
Maspin is useful in the distinction of pancreatic adenocarcinoma from chronic pancreatitis: a tissue microarray based study.
Neoplasm Metastasis
Maspin nuclear localization is linked to favorable morphological features in pulmonary adenocarcinoma.
Neoplasm Metastasis
Maspin sensitizes prostate cancer cells to doxazosin-induced apoptosis.
Neoplasm Metastasis
Maspin, VEGF and p53 Expression in Small Biopsies of Primary Advanced Lung Cancer and Relationship with Clinicopathologic Parameters.
Neoplasm Metastasis
Matriptase and HAI-1 are expressed by normal and malignant epithelial cells in vitro and in vivo.
Neoplasm Metastasis
Mechanisms of disease: the impact of antithrombotic therapy in cancer patients.
Neoplasm Metastasis
Membrane-Anchored Serine Proteases and Protease-Activated Receptor-2-Mediated Signaling: Co-Conspirators in Cancer Progression.
Neoplasm Metastasis
Mesotrypsin promotes malignant growth of breast cancer cells through shedding of CD109.
Neoplasm Metastasis
Metastatic suppressor CD44 is related with oxidative stress in breast cancer cell lines.
Neoplasm Metastasis
Micro-lymph node metastasis and its correlation with cathepsin D expression in early gastric cancer.
Neoplasm Metastasis
microRNA-186 Suppresses Cell Proliferation and Metastasis Through Targeting Sentrin Specific Protease 1 in Renal Cell Carcinoma.
Neoplasm Metastasis
Microsphere-Based Nanoindentation for the Monitoring of Cellular Cortical Stiffness Regulated by MT1-MMP.
Neoplasm Metastasis
miR-5089-5p suppresses castration-resistant prostate cancer resistance to enzalutamide and metastasis via miR-5089-5p/SPINK1/ MAPK/MMP9 signaling.
Neoplasm Metastasis
Molecular cloning of cDNA for matriptase, a matrix-degrading serine protease with trypsin-like activity.
Neoplasm Metastasis
Monitoring of chemotherapy successfulness of platina/taxol chemotherapy protocol by using determination of serum urokinase plasminogen activator (uPA) and soluble urokinase plasminogen activator receptor (suPAR) in patients with ovarian carcinoma FIGO II and III stage.
Neoplasm Metastasis
MT1-MMP recruits the ER-Golgi SNARE Bet1 for efficient MT1-MMP transport to the plasma membrane.
Neoplasm Metastasis
Neutrophil elastase as a diagnostic marker and therapeutic target in colorectal cancers.
Neoplasm Metastasis
New ELISA for quantitation of human urokinase receptor (CD87) in cancer.
Neoplasm Metastasis
Nimbolide inhibits invasion and migration, and down-regulates uPAR chemokine gene expression, in two breast cancer cell lines.
Neoplasm Metastasis
Nitric oxide increases the invasion of pancreatic cancer cells via activation of the PI3K-AKT and RhoA pathways after carbon ion irradiation.
Neoplasm Metastasis
NLRP7 deubiquitination by USP10 promotes tumor progression and tumor-associated macrophage polarization in colorectal cancer.
Neoplasm Metastasis
Nonpolarized secretion of human meprin alpha in colorectal cancer generates an increased proteolytic potential in the stroma.
Neoplasm Metastasis
Nuclear cathepsin D enhances TRPS1 transcriptional repressor function to regulate cell cycle progression and transformation in human breast cancer cells.
Neoplasm Metastasis
Nuclear translocation of ADAM-10 contributes to the pathogenesis and progression of human prostate cancer.
Neoplasm Metastasis
Osteoblast-derived TGF-beta1 modulates matrix degrading protease expression and activity in prostate cancer cells.
Neoplasm Metastasis
Osteonectin promotes prostate cancer cell migration and invasion: a possible mechanism for metastasis to bone.
Neoplasm Metastasis
Osteoprotegerin expression in triple-negative breast cancer cells promotes metastasis.
Neoplasm Metastasis
Overexpression in colorectal carcinoma of two lysosomal enzymes, CLN2 and CLN1, involved in neuronal ceroid lipofuscinosis.
Neoplasm Metastasis
Overexpression of a hybrid gene consisting of the amino-terminal fragment of urokinase and carboxyl-terminal domain of bikunin suppresses invasion and migration of human ovarian cancer cells in vitro.
Neoplasm Metastasis
Overexpression of a secretory leukocyte protease inhibitor in human gastric cancer.
Neoplasm Metastasis
Overexpression of the urokinase receptor mRNA splice variant uPAR-del4/5 affects tumor-associated processes of breast cancer cells in vitro and in vivo.
Neoplasm Metastasis
Overexpression of TMPRSS4 in non-small cell lung cancer is associated with poor prognosis in patients with squamous histology.
Neoplasm Metastasis
Overexpression of urinary plasminogen activator (uPA) protein and mRNA in thyroid carcinogenesis.
Neoplasm Metastasis
p202, an interferon-inducible protein, mediates multiple antitumor activities in human pancreatic cancer xenograft models.
Neoplasm Metastasis
Paradoxical expression of maspin in gastric carcinomas: correlation with carcinogenesis and progression.
Neoplasm Metastasis
Pathophysiological functions of cathepsin D: Targeting its catalytic activity versus its protein binding activity?
Neoplasm Metastasis
Phloretin suppresses metastasis by targeting protease and inhibits cancer stemness and angiogenesis in human cervical cancer cells.
Neoplasm Metastasis
Piperidine carbamate peptidomimetic inhibitors of the serine proteases HGFA, matriptase and hepsin.
Neoplasm Metastasis
Plasminogen activator inhibitor-1 (PAI-1) gene transfection inhibits the liver metastasis of pancreatic cancer by preventing angiogenesis.
Neoplasm Metastasis
Plasminogen activator inhibitor-2 is highly tolerant to P8 residue substitution--implications for serpin mechanistic model and prediction of nsSNP activities.
Neoplasm Metastasis
Pleiotrophic inhibition of pericellular urokinase-type plasminogen activator system by endogenous tumor suppressive maspin.
Neoplasm Metastasis
Pleiotropic functions of the tumor- and metastasis-suppressing matrix metalloproteinase-8 in mammary cancer in MMTV-PyMT transgenic mice.
Neoplasm Metastasis
Pneumococcal zinc metalloproteinase ZmpC cleaves human matrix metalloproteinase 9 and is a virulence factor in experimental pneumonia.
Neoplasm Metastasis
Potent blockade of hepatocyte growth factor-stimulated cell motility, matrix invasion and branching morphogenesis by antagonists of Grb2 Src homology 2 domain interactions.
Neoplasm Metastasis
Potential molecular targets of tea polyphenols in human tumor cells: significance in cancer prevention.
Neoplasm Metastasis
Predictive value of cathepsin-D for cervical lymph node metastasis in head and neck squamous cell carcinoma.
Neoplasm Metastasis
Prevention of early liver metastasis after pancreatectomy by perioperative administration of a nuclear factor-?B inhibitor in mice.
Neoplasm Metastasis
Procedures for the quantitative protein determination of urokinase and its inhibitor, PAI-1, in human breast cancer tissue extracts by ELISA.
Neoplasm Metastasis
Prognostic impact of urokinase-type plasminogen activator (PA), PA inhibitor type-1, and tissue-type PA antigen levels in node-negative breast cancer: a prospective study on multicenter basis.
Neoplasm Metastasis
Prognostic role of maspin expression in patients with cervical dysplasia and cervical cancer.
Neoplasm Metastasis
Prognostic significance of USP22 as an oncogene in papillary thyroid carcinoma.
Neoplasm Metastasis
Prostate Cancer-Associated Kallikrein-Related Peptidase 4 Activates Matrix Metalloproteinase-1 and Thrombospondin-1.
Neoplasm Metastasis
Prostate-specific antigen activates single-chain urokinase-type plasminogen activator.
Neoplasm Metastasis
Prostate-specific antigen, a serine protease, facilitates human prostate cancer cell invasion.
Neoplasm Metastasis
Prostatic human kallikrein 2 inactivates and complexes with plasminogen activator inhibitor-1.
Neoplasm Metastasis
Protease activated receptor 2 signaling promotes self-renewal and metastasis in colorectal cancer through ?-catenin and periostin.
Neoplasm Metastasis
Protease Nexin I is a feedback regulator of EGF/PKC/MAPK/EGR1 signaling in breast cancer cells metastasis and stemness.
Neoplasm Metastasis
Protein C inhibitor inhibits breast cancer cell growth, metastasis and angiogenesis independently of its protease inhibitory activity.
Neoplasm Metastasis
Protumor activities of the immune response: insights in the mechanisms of immunological shift, oncotraining, and oncopromotion.
Neoplasm Metastasis
PSA affects prostate cancer cell invasion in vitro and induces an osteoblastic phenotype in bone in vivo.
Neoplasm Metastasis
Quantum dots based molecular beacons for in vitro and in vivo detection of MMP-2 on tumor.
Neoplasm Metastasis
Quercetin inhibits invasion, migration and signalling molecules involved in cell survival and proliferation of prostate cancer cell line (PC-3).
Neoplasm Metastasis
Radiation-induced lung metastasis development is MT1-MMP-dependent in a triple-negative breast cancer mouse model.
Neoplasm Metastasis
Reduced Proteolytic Shedding of Receptor Tyrosine Kinases Is a Post-Translational Mechanism of Kinase Inhibitor Resistance.
Neoplasm Metastasis
Reduction of breast carcinoma tumor growth and lung colonization by overexpression of the soluble urokinase-type plasminogen activator receptor (CD87).
Neoplasm Metastasis
Reduction of experimental human fibrosarcoma lung metastasis in mice by adenovirus-mediated cystatin C overexpression in the host.
Neoplasm Metastasis
Regulation of DNA methylation in human breast cancer. Effect on the urokinase-type plasminogen activator gene production and tumor invasion.
Neoplasm Metastasis
Relationship between urokinase-type plasminogen receptor, interleukin-8 gene expression and clinicopathological features in gastric cancer.
Neoplasm Metastasis
Reprogramming epigenetic silencing: artificial transcription factors synergize with chromatin remodeling drugs to reactivate the tumor suppressor mammary serine protease inhibitor.
Neoplasm Metastasis
RNAi-mediated downregulation of urokinase plasminogen activator receptor and matrix metalloprotease-9 in human breast cancer cells results in decreased tumor invasion, angiogenesis and growth.
Neoplasm Metastasis
Role of MMP9 on invadopodia formation in cells from adenoid cystic carcinoma. Study by laser scanning confocal microscopy.
Neoplasm Metastasis
ROLE OF PLASMINOGEN ACTIVATOR INHIBITOR-1 IN UROKINASE'S PARADOXICAL IN VIVO TUMOR SUPPRESSING OR PROMOTING EFFECTS.
Neoplasm Metastasis
Role of protease activated receptor-2 in lymph node metastasis of uterine cervical cancers.
Neoplasm Metastasis
Role of protease activated receptor-2 in tumor advancement of ovarian cancers.
Neoplasm Metastasis
Role of squamous cell carcinoma antigen 1 expression in the invasive potential of head and neck squamous cell carcinoma.
Neoplasm Metastasis
Role of urokinase-type plasminogen activator and inhibitory effect of protease inhibitor in invasion and metastasis of pancreatic cancer.
Neoplasm Metastasis
Secretion of urokinase and metalloproteinase-9 induced by staurosporine is dependent on a tyrosine kinase pathway in mammary tumor cells.
Neoplasm Metastasis
Secretory leukocyte protease inhibitor (SLPI) as a potential target for inhibiting metastasis of triple-negative breast cancers.
Neoplasm Metastasis
Secretory leukocyte protease inhibitor is associated with MMP-2 and MMP-9 to promote migration and invasion in SNU638 gastric cancer cells.
Neoplasm Metastasis
Secretory leukocyte protease inhibitor promotes the tumorigenic and metastatic potential of cancer cells.
Neoplasm Metastasis
Selection criteria for epirubicin-based adjuvant chemotherapy in node-negative breast cancer.
Neoplasm Metastasis
Selective attenuation of the extrinsic limb of the tissue factor-driven coagulation protease cascade by occupancy of a novel peptidyl docking site on tissue factor.
Neoplasm Metastasis
Sense and antisense cDNA transfection of CD36 (glycoprotein IV) in melanoma cells. Role of CD36 as a thrombospondin receptor.
Neoplasm Metastasis
Sequential production and activation of matrix-metalloproteinase-9 (MMP-9) with breast cancer progression.
Neoplasm Metastasis
Serine protease inhibitor Kazal type 1 (SPINK1) downregulates E-cadherin and induces EMT of hepatoma cells to promote hepatocellular carcinoma metastasis via the MEK/ERK signaling pathway.
Neoplasm Metastasis
SerpinE2 promotes multiple cell proliferation and drug resistance in osteosarcoma.
Neoplasm Metastasis
Significance of the tumor protease Cathepsin D for the biology of breast cancer.
Neoplasm Metastasis
Single cell multiplexed assay for proteolytic activity using droplet microfluidics.
Neoplasm Metastasis
SLPI promotes the gastric cancer growth and metastasis by regulating the expression of P53, Bcl-2 and Caspase-8.
Neoplasm Metastasis
Sodium hydrogen exchanger and phospholipase D are required for alpha1-adrenergic receptor stimulation of metalloproteinase-9 and cellular invasion in CCL39 fibroblasts.
Neoplasm Metastasis
Spatial distribution of endogenous tissue protease activity in gastric carcinoma mapped by MALDI mass spectrometry imaging.
Neoplasm Metastasis
SPINK6 Promotes Metastasis of Nasopharyngeal Carcinoma via Binding and Activation of Epithelial Growth Factor Receptor.
Neoplasm Metastasis
SRC family kinases: potential targets for the treatment of human cancer and leukemia.
Neoplasm Metastasis
Stromal cell-derived factor-1/CXC receptor 4 and b1 integrin interaction regulates urokinase-type plasminogen activator expression in human colorectal cancer cells.
Neoplasm Metastasis
Structural basis for selectivity of a small molecule, S1-binding, submicromolar inhibitor of urokinase-type plasminogen activator.
Neoplasm Metastasis
Structure-based design, synthesis and SAR of a novel series of thiopheneamidine urokinase plasminogen activator inhibitors.
Neoplasm Metastasis
Structure-function studies on inhibitory activity of Bungarus multicinctus protease inhibitor-like protein on matrix metalloprotease-2, and invasion and migration of human neuroblastoma SK-N-SH cells.
Neoplasm Metastasis
Structure-guided discovery of 1,3,5 tri-substituted benzenes as potent and selective matriptase inhibitors exhibiting in vivo antitumor efficacy.
Neoplasm Metastasis
Substrate-derived triazolo- and azapeptides as inhibitors of cathepsins K and S.
Neoplasm Metastasis
Suppression of asparaginyl endopeptidase attenuates breast cancer-induced bone pain through inhibition of neurotrophin receptors.
Neoplasm Metastasis
Suppression of invasion and peritoneal carcinomatosis of ovarian cancer cell line by overexpression of bikunin.
Neoplasm Metastasis
Suppression of urokinase-type plasminogen activator expression from human ovarian cancer cells by urinary trypsin inhibitor.
Neoplasm Metastasis
Synthesis, solution structure, and biological evaluation of urokinase type plasminogen activator (uPA)-derived receptor binding domain mimetics.
Neoplasm Metastasis
Tamoxifen induces the expression of maspin through estrogen receptor-alpha.
Neoplasm Metastasis
Targeted inhibition of cell-surface serine protease Hepsin blocks prostate cancer bone metastasis.
Neoplasm Metastasis
Targeting an autocrine IL-6-SPINK1 signaling axis to suppress metastatic spread in ovarian clear cell carcinoma.
Neoplasm Metastasis
Targeting mast cells tryptase in tumor microenvironment: a potential antiangiogenetic strategy.
Neoplasm Metastasis
Targeting serous epithelial ovarian cancer with designer zinc finger transcription factors.
Neoplasm Metastasis
Targeting the intestinal TMPRSS2 protease to prevent SARS-CoV-2 entry into enterocytes-prospects and challenges.
Neoplasm Metastasis
Targeting ubiquitin-specific protease 22 suppresses growth and metastasis of anaplastic thyroid carcinoma.
Neoplasm Metastasis
Targeting urokinase-type plasminogen activator and its receptor for cancer therapy.
Neoplasm Metastasis
Testes-specific protease 50 (TSP50) promotes invasion and metastasis by inducing EMT in gastric cancer.
Neoplasm Metastasis
Testes-specific protease 50 promotes cell invasion and metastasis by increasing NF-kappaB-dependent matrix metalloproteinase-9 expression.
Neoplasm Metastasis
Tfs1p, a member of the PEBP family, inhibits the Ira2p but not the Ira1p Ras GTPase-activating protein in Saccharomyces cerevisiae.
Neoplasm Metastasis
TGF-beta1 promotes liver metastasis of pancreatic cancer by modulating the capacity of cellular invasion.
Neoplasm Metastasis
The ADAMTS1 protease gene is required for mammary tumor growth and metastasis.
Neoplasm Metastasis
The androgen-regulated protease TMPRSS2 activates a proteolytic cascade involving components of the tumor microenvironment and promotes prostate cancer metastasis.
Neoplasm Metastasis
The compound 14-keto-stypodiol diacetate from the algae Stypopodium flabelliforme inhibits microtubules and cell proliferation in DU-145 human prostatic cells.
Neoplasm Metastasis
The effect of 3-bromopyruvate on the properties of cathepsin B in the aspect of metastatic potential of colon cancer cells.
Neoplasm Metastasis
The effect of dietary supplementation with limonene or myo-inositol on the induction of neoplasia and matrix metalloproteinase and plasminogen activator activities in accessory sex organs of male Lobund-Wistar rats.
Neoplasm Metastasis
The effect of essential fatty acids on growth and urokinase-type plasminogen activator production in human prostate DU-145 cells.
Neoplasm Metastasis
The effect of gamma-linolenic acid and eicosapentaenoic acid on urokinase activity.
Neoplasm Metastasis
The ERK/MAPK pathway regulates the activity of the human tissue factor pathway inhibitor-2 promoter.
Neoplasm Metastasis
The expression of the ADAMs proteases in prostate cancer cell lines and their regulation by dihydrotestosterone.
Neoplasm Metastasis
The expression of TMPRSS4 and Erk1 correlates with metastasis and poor prognosis in Chinese patients with gastric cancer.
Neoplasm Metastasis
The field bean protease inhibitor has the potential to suppress B16F10 melanoma cell lung metastasis in mice.
Neoplasm Metastasis
The HtrA1 serine protease is down-regulated during human melanoma progression and represses growth of metastatic melanoma cells.
Neoplasm Metastasis
The membrane tethered matrix metalloproteinase MT1-MMP at the forefront of melanoma cell invasion and metastasis.
Neoplasm Metastasis
The Mitochondrial Unfoldase-Peptidase Complex ClpXP Controls Bioenergetics Stress and Metastasis.
Neoplasm Metastasis
The multi-functional serpin, protein C inhibitor: beyond thrombosis and hemostasis.
Neoplasm Metastasis
The novel serine protease tumor-associated differentially expressed gene-14 (KLK8/Neuropsin/Ovasin) is highly overexpressed in cervical cancer.
Neoplasm Metastasis
The novel serine protease tumor-associated differentially expressed gene-15 (matriptase/MT-SP1) is highly overexpressed in cervical carcinoma.
Neoplasm Metastasis
The osteoclast-associated protease cathepsin K is expressed in human breast carcinoma.
Neoplasm Metastasis
The protease activated receptor 1 gene variation IVSn -14A>T is associated with distant metastasis and cancer-specific survival in renal cell carcinoma.
Neoplasm Metastasis
The Protease Activated Receptor2 Promotes Rab5a Mediated Generation of Pro-metastatic Microvesicles.
Neoplasm Metastasis
The role of annexin II in angiogenesis and tumor progression: a potential therapeutic target.
Neoplasm Metastasis
The role of cancer cell protease in invasion of rat ascites hepatome AH 109 A cells, with special reference to pulmonary metastasis of subcutaneously transplanted cells.
Neoplasm Metastasis
The role of endocytic Rab GTPases in regulation of growth factor signaling and the migration and invasion of tumor cells.
Neoplasm Metastasis
The role of nutraceutical proteins and peptides in apoptosis, angiogenesis, and metastasis of cancer cells.
Neoplasm Metastasis
The role of urokinase-type plasminogen activator and its inhibitor PAI-1 in gastric cancer.
Neoplasm Metastasis
The secretory leukocyte protease inhibitor (SLPI) suppresses cancer cell invasion but promotes blood-borne metastasis via an invasion-independent pathway.
Neoplasm Metastasis
The Secretory Leukocyte Protease Inhibitor Is a Type 1 Insulin-Like Growth Factor Receptor-Regulated Protein that Protects against Liver Metastasis by Attenuating the Host Proinflammatory Response.
Neoplasm Metastasis
The serine protease inhibitor protease nexin-1 controls mammary cancer metastasis through LRP-1-mediated MMP-9 expression.
Neoplasm Metastasis
The serine protease stratum corneum chymotryptic enzyme (kallikrein 7) is highly overexpressed in squamous cervical cancer cells.
Neoplasm Metastasis
The surface of prostate carcinoma DU145 cells mediates the inhibition of urokinase-type plasminogen activator by maspin.
Neoplasm Metastasis
The urokinase plasminogen activating system in thyroid cancer: clinical implications.
Neoplasm Metastasis
The urokinase plasminogen activator system in breast cancer invasion and metastasis.
Neoplasm Metastasis
The urokinase plasminogen activator system: a target for anti-cancer therapy.
Neoplasm Metastasis
The urokinase receptor (uPAR, CD87) as a target for tumor therapy: uPA-silica particles (SP-uPA) as a new tool for assessing synthetic peptides to interfere with uPA/uPA-receptor interaction.
Neoplasm Metastasis
Therapeutic efficacy of once-daily oral administration of a Kunitz-type protease inhibitor, bikunin, in a mouse model and in human cancer.
Neoplasm Metastasis
Thrombin induces tumor invasion through the induction and association of matrix metalloproteinase-9 and beta1-integrin on the cell surface.
Neoplasm Metastasis
Thrombomodulin, a receptor for the serine protease thrombin, is decreased in primary tumors and metastases but increased in ascitic fluids of patients with advanced ovarian cancer FIGO IIIc.
Neoplasm Metastasis
Timp3 loss accelerates tumour invasion and increases prostate inflammation in a mouse model of prostate cancer.
Neoplasm Metastasis
Tissue factor and cell signalling in cancer progression and thrombosis.
Neoplasm Metastasis
Tissue inhibitor of metalloproteinases-1-induced scattered liver metastasis is mediated by hypoxia-inducible factor-1?.
Neoplasm Metastasis
Tissue inhibitor of metalloproteinases-2 inhibits bFGF-induced human microvascular endothelial cell proliferation.
Neoplasm Metastasis
Tissue inhibitors of metalloproteinases (TIMP) in invasion and proliferation.
Neoplasm Metastasis
TLS-CHOP represses miR-486 expression, inducing upregulation of a metastasis regulator PAI-1 in human myxoid liposarcoma.
Neoplasm Metastasis
Transcriptional and posttranscriptional activation of urokinase plasminogen activator gene expression in metastatic tumor cells.
Neoplasm Metastasis
Transfected cathepsin D stimulates high density cancer cell growth by inactivating secreted growth inhibitors.
Neoplasm Metastasis
Transmembrane Protease TMPRSS4 Promotes the Formation and Development of Mismatch Repair Deficient Colon Cancer Liver Metastasis.
Neoplasm Metastasis
Truncated Human Cathepsin L, Encoded by a Novel Splice Variant, Exhibits Altered Subcellular Localization and Cytotoxicity.
Neoplasm Metastasis
Tumor cell invasion is promoted by activation of protease activated receptor-1 in cooperation with the alpha vbeta 5 integrin.
Neoplasm Metastasis
Tumor-host interactions contribute to the elevated expression level of alpha1-antichymotrypsin in metastatic breast tumor xenografts.
Neoplasm Metastasis
Tumor-suppressive maspin regulates cell response to oxidative stress by direct interaction with glutathione S-transferase.
Neoplasm Metastasis
Tumour but not stromal expression of ?3 integrin is essential, and is required early, for spontaneous dissemination of bone-metastatic breast cancer.
Neoplasm Metastasis
Tumour-associated urokinase-type plasminogen activator (uPA) and its inhibitor PAI-1 in normal and neoplastic tissues of patients with squamous cell cancer of the oral cavity - clinical relevance and prognostic value.
Neoplasm Metastasis
Ubiquitin-speci?c protease 4 promotes metastasis of hepatocellular carcinoma by increasing TGF-? signaling-induced epithelial-mesenchymal transition.
Neoplasm Metastasis
Ubiquitin-specific peptidase 46 (USP46) suppresses renal cell carcinoma tumorigenesis through AKT pathway inactivation.
Neoplasm Metastasis
Ubiquitin-specific protease 11 serves as a marker of poor prognosis and promotes metastasis in hepatocellular carcinoma.
Neoplasm Metastasis
Ubiquitin-specific protease 14 (USP14) promotes proliferation and metastasis in pancreatic ductal adenocarcinoma.
Neoplasm Metastasis
Ubiquitin-specific protease 14 expression in colorectal cancer is associated with liver and lymph node metastases.
Neoplasm Metastasis
Ubiquitin-specific protease 14 regulates cell proliferation and apoptosis in oral squamous cell carcinoma.
Neoplasm Metastasis
Ubiquitin-Specific Protease 21 Promotes Colorectal Cancer Metastasis by Acting as a Fra-1 Deubiquitinase.
Neoplasm Metastasis
Ubiquitin-specific protease 22 is critical to in vivo angiogenesis, growth and metastasis of non-small cell lung cancer.
Neoplasm Metastasis
Ubiquitin?specific protease 22?induced autophagy is correlated with poor prognosis of pancreatic cancer.
Neoplasm Metastasis
uPA and PAI-1 as biomarkers in breast cancer: validated for clinical use in level-of-evidence-1 studies.
Neoplasm Metastasis
uPA-silica-Particles (SP-uPA): a novel analytical system to investigate uPA-uPAR interaction and to test synthetic uPAR antagonists as potential cancer therapeutics.
Neoplasm Metastasis
Upregulation of maspin expression in human cervical carcinoma cells by transforming growth factor ?1 through the convergence of Smad and non-Smad signaling pathways.
Neoplasm Metastasis
Upregulation of tissue kallikrein, kinin B1 receptor, and kinin B2 receptor in mast and giant cells infiltrating oesophageal squamous cell carcinoma.
Neoplasm Metastasis
Urokinase plasminogen activator and its inhibitor, PAI-1, as prognostic markers in breast cancer: from pilot to level 1 evidence studies.
Neoplasm Metastasis
Urokinase plasminogen activator as a prognostic marker in different subgroups of patients with breast cancer.
Neoplasm Metastasis
Urokinase plasminogen activator predicts poor prognosis in hepatocellular carcinoma.
Neoplasm Metastasis
Urokinase plasminogen activator receptor choreographs multiple ligand interactions: implications for tumor progression and therapy.
Neoplasm Metastasis
Urokinase plasminogen activator: a prognostic marker in breast cancer including patients with axillary node-negative disease.
Neoplasm Metastasis
Urokinase plasminogen activator: a prognostic marker in multiple types of cancer.
Neoplasm Metastasis
Urokinase receptor localization in breast cancer and benign lesions assessed by in situ hybridization and immunohistochemistry.
Neoplasm Metastasis
Urokinase-mediated recruitment of myeloid-derived suppressor cells and their suppressive mechanisms are blocked by MUC1/sec.
Neoplasm Metastasis
Urokinase-plasminogen activator, a new and independent prognostic marker in breast cancer.
Neoplasm Metastasis
Urokinase-type plasminogen activator (uPA) and its receptor (uPAR): development of antagonists of uPA/uPAR interaction and their effects in vitro and in vivo.
Neoplasm Metastasis
Urokinase-type plasminogen activator and outcome in Dukes' B colorectal cancer.
Neoplasm Metastasis
Urokinase-type plasminogen activator in colorectal cancer: relationship with clinicopathological features and patient outcome.
Neoplasm Metastasis
Urokinase-type plasminogen activator, its inhibitor, and its receptor in patients with upper urinary tract carcinoma.
Neoplasm Metastasis
Urokinase-type plasminogen activator: a potent marker of metastatic potential in human cancers.
Neoplasm Metastasis
Use of HIV protease inhibitors to block Kaposi's sarcoma and tumour growth.
Neoplasm Metastasis
USP1 Maintains the Survival of Liver Circulating Tumor Cells by Deubiquitinating and Stabilizing TBLR1.
Neoplasm Metastasis
USP21 promotes cell proliferation and metastasis through suppressing EZH2 ubiquitination in bladder carcinoma.
Neoplasm Metastasis
Validation of immunolocalization of the urokinase receptor expression in ductal carcinoma in situ of the breast: comparison with detection by non-isotopic in-situ hybridization.
Neoplasm Metastasis
Verapamil inhibits tumor protease production, local invasion and metastasis development in murine carcinoma cells.
Neoplasm Metastasis
Zinc oxide nanoparticles enhance expression of maspin in human breast cancer cells.
Neoplasm Metastasis
[Activity of cathepsin D in the blood serum and urine of patients with cancer of the stomach, pancreas and liver]
Neoplasm Metastasis
[Clinical and prognostic significance of tumor-associated proteases in gynecologic oncology]
Neoplasm Metastasis
[Correlation of prostate-specific antigen with the progression and metastasis of human prostate cancer].
Neoplasm Metastasis
[Inhibitory effect of FOY-305 on liver metastasis of the pancreatic cancer]
Neoplasm Metastasis
[The clinical prospects for the study of the plasminogen activation system in breast cancer]
Neoplasm Metastasis
[The inhibitory effect of nafamostat mesilate (FUT-175) on liver metastasis]
Neoplasm Metastasis
[The role of cathepsins and the plasminogen activator/inhibitor system in colorectal cancer]
Neoplasm Micrometastasis
Evaluating the role of serine protease inhibition in the management of tumor micrometastases.
Neoplasm Micrometastasis
Membrane proteases as potential diagnostic and therapeutic targets for breast malignancy.
Neoplasms
'Pseudopalisading' necrosis in glioblastoma: a familiar morphologic feature that links vascular pathology, hypoxia, and angiogenesis.
Neoplasms
(4-aminomethyl)phenylguanidine derivatives as nonpeptidic highly selective inhibitors of human urokinase.
Neoplasms
2, 3-Dihydro-3?-methoxy Withaferin-A Lacks Anti-Metastasis Potency: Bioinformatics and Experimental Evidences.
Neoplasms
25-methoxyl-dammarane-3?, 12?, 20-triol and artemisinin synergistically inhibit MDA-MB-231 cell proliferation through downregulation of testes-specific protease 50 (TSP50) expression.
Neoplasms
3-Cl-AHPC inhibits pro-HGF maturation by inducing matriptase/HAI-1 complex formation.
Neoplasms
3D-QSAR CoMFA studies on trypsin-like serine protease inhibitors: a comparative selectivity analysis.
Neoplasms
3D-quantitative structure-activity relationship and docking studies of coumarin derivatives as tissue kallikrein 7 inhibitors.
Neoplasms
99mTc-labeled field bean protease inhibitor can function as an efficient tumor detecting agent.
Neoplasms
?-Ketobenzothiazole Serine Protease Inhibitors of Aberrant HGF/c-MET and MSP/RON Kinase Pathway Signaling in Cancer.
Neoplasms
?-Secretase Activity Is Required for Regulated Intramembrane Proteolysis of Tumor Necrosis Factor (TNF) Receptor 1 and TNF-mediated Pro-apoptotic Signaling.
Neoplasms
A bacterial protease depletes c-MYC and increases survival in mouse models of bladder and colon cancer.
Neoplasms
A CASP-8 mutation recognized by cytolytic T lymphocytes on a human head and neck carcinoma.
Neoplasms
A clonal human chondrosarcoma cell line produces an anti-angiogenic antitumor factor.
Neoplasms
A comparative study of protein expression in primary colorectal cancer and synchronous hepatic metastases: the significance of matrix metalloproteinase-1 expression as a predictor of liver metastasis.
Neoplasms
A cytosol protease from the estrogen-resistant C3H mammary carcinoma increases the affinity of the estrogen receptor for DNA in vitro.
Neoplasms
A detrimental mutation on USP40 unlocks the tumorigenesis in a rare case of lung cancer.
Neoplasms
A disintegrin and metalloproteinase 9 is involved in ectodomain shedding of receptor-binding cancer antigen expressed on SiSo cells.
Neoplasms
A diverse family of proteins containing tumor necrosis factor receptor-associated factor domains.
Neoplasms
A DNA probe study on the origin of the cancer recognition, immunedefense suppression and serine protease protection peptide.
Neoplasms
A dual magnetic resonance imaging/fluorescent contrast agent for Cathepsin-D detection.
Neoplasms
A Dual-Response DNA Probe for Simultaneously Monitoring Enzymatic Activity and Environmental pH Using a Nanopore.
Neoplasms
A fluorescent study of ligands for guanidinobenzoatase, a protease associated with tumour cells.
Neoplasms
A JUN N-terminal kinase inhibitor induces ectodomain shedding of the cancer-associated membrane protease Prss14/epithin via protein kinase C?II.
Neoplasms
A Kunitz-type protease inhibitor, bikunin, inhibits ovarian cancer cell invasion by blocking the calcium-dependent transforming growth factor-beta 1 signaling cascade.
Neoplasms
A mathematical model for the roles of pericytes and macrophages in the initiation of angiogenesis. I. The role of protease inhibitors in preventing angiogenesis.
Neoplasms
A metalloproteinase, capable of destroying cultured brain tissue isolated from rat glioma cells.
Neoplasms
A mitochondrial protease that cleaves the precursor of ornithine carbamoyltransferase. Purification and properties.
Neoplasms
A monoclonal antibody against hinge-cleaved IgG restores effector function to proteolytically-inactivated IgGs in vitro and in vivo.
Neoplasms
A Multiresponsive Nanohybrid to Enhance the Lysosomal Delivery of Oxygen and Photosensitizers.
Neoplasms
A natural bacterial-derived product, the metalloprotease arazyme, inhibits metastatic murine melanoma by inducing MMP-8 cross-reactive antibodies.
Neoplasms
A novel antisense oligonucleotide targeting survivin expression induces apoptosis and sensitizes lung cancer cells to chemotherapy.
Neoplasms
A Novel Antitumor Prodrug Platform Designed to Be Cleaved by the Endoprotease Legumain.
Neoplasms
A novel expression and purification system for the production of enzymatic and biologically active human granzyme B.
Neoplasms
A novel FAP?-based Z-Gly-Pro epirubicin prodrug for improving tumor-targeting chemotherapy.
Neoplasms
A novel peptide-based electrochemical biosensor for the determination of a metastasis-linked protease in pancreatic cancer cells.
Neoplasms
A novel serine protease highly expressed in the pancreas is expressed in various kinds of cancer cells.
Neoplasms
A novel strategy for the tumor angiogenesis-targeted gene therapy: generation of angiostatin from endogenous plasminogen by protease gene transfer.
Neoplasms
A novel transmembrane serine protease (TMPRSS3) overexpressed in pancreatic cancer.
Neoplasms
A novel transport and delivery mechanism underpins the effectiveness of prolyl-m-sarcolysyl-p-fluorophenylalanine (PSF) in a human melanoma xenograft nude-mouse model.
Neoplasms
A Phase II, Multicenter, Single-Arm Study of Mipsagargin (G-202) as a Second-Line Therapy Following Sorafenib for Adult Patients with Progressive Advanced Hepatocellular Carcinoma.
Neoplasms
A potentially novel peptidase, resembling but distinct from neutrophil elastase, produced by carcinoma cells.
Neoplasms
A preliminary study: is fibulin 1 a friend or an enemy that needs to be silenced with siRNAs for mesothelioma?
Neoplasms
A prospective study on the prognostic significance of urokinase-type plasminogen activator levels in breast cancer tissue.
Neoplasms
A prostate-specific antigen activated N-(2-hydroxypropyl) methacrylamide copolymer prodrug as dual-targeted therapy for prostate cancer.
Neoplasms
A protease storm cleaves a cell-cell adhesion molecule in cancer: multiple proteases converge to regulate PTPmu in glioma cells.
Neoplasms
A proteolytic activity in a human breast cancer cell line which is inhibited by the anticarcinogenic Bowman-Birk protease inhibitor.
Neoplasms
A review of nanoparticle drug delivery systems responsive to endogenous breast cancer microenvironment.
Neoplasms
A review on peptide functionalized graphene derivatives as nanotools for biosensing.
Neoplasms
A role for tissue factor in cell adhesion and migration mediated by interaction with actin-binding protein 280.
Neoplasms
A secreted form of ADAM9 promotes carcinoma invasion through tumor-stromal interactions.
Neoplasms
A soybean Kunitz trypsin inhibitor suppresses ovarian cancer cell invasion by blocking urokinase upregulation.
Neoplasms
A specific, transmembrane interface regulates fibroblast activation protein (FAP) homodimerization, trafficking and exopeptidase activity.
Neoplasms
A urokinase-activated recombinant anthrax toxin is selectively cytotoxic to many human tumor cell types.
Neoplasms
AbCD133 Modified ?CT1 Loaded Target Magnetic Mesoporous Silica Nano-Drugcarriers Can Sensitizes Glioma Cancer Stem Cells to TMZ and Have Therapeutic Potential on TMZ Resistant Glioblastoma.
Neoplasms
Aberrant DNA methylation of apoptotic signaling genes in patients responsive and nonresponsive to therapy for cervical carcinoma.
Neoplasms
Aberrant expression of the maspin gene associated with epigenetic modification in melanoma cells.
Neoplasms
Aberrant maspin expression is involved in early carcinogenesis of gallbladder cancer.
Neoplasms
Abnormal regulation of soluble and anchored IL-6 receptor in monocytes from patients with essential thrombocythemia.
Neoplasms
Absence of host plasminogen activator inhibitor 1 prevents cancer invasion and vascularization.
Neoplasms
Abundant expression of the membrane-anchored protease-regulator RECK in the anterior pituitary gland and its implication in the growth hormone/insulin-like growth factor 1 axis in mice.
Neoplasms
Accelerated beta-cell destruction in adoptively transferred autoimmune diabetes correlates with an increased expression of the genes coding for TNF-alpha and granzyme A in the intra-islet infiltrates.
Neoplasms
Acetylation-dependent regulation of MDM2 E3 ligase activity dictates its oncogenic function.
Neoplasms
Acquired immunodeficiency syndrome-related Kaposi's sarcoma regression after highly active antiretroviral therapy: biologic correlates of clinical outcome.
Neoplasms
Activatable Carbocyanine Dimers for Photoacoustic and Fluorescent Detection of Protease Activity.
Neoplasms
Activatable oligomerizable imaging agents for photoacoustic imaging of furin-like activity in living subjects.
Neoplasms
Activatable Zymography Probes Enable In Situ Localization of Protease Dysregulation in Cancer.
Neoplasms
Activation mechanisms of the urokinase-type plasminogen activator promoter by hepatocyte growth factor/scatter factor.
Neoplasms
Activation of actin-cleavable interleukin 1beta-converting enzyme (ICE) family protease CPP-32 during chemotherapeutic agent-induced apoptosis in ovarian carcinoma cells.
Neoplasms
Activation of CPP32-like protease in tumor necrosis factor-induced apoptosis is dependent on mitochondrial function.
Neoplasms
Activation of ERK signaling upon alternative protease nexin-1 internalization mediated by syndecan-1.
Neoplasms
Activation of hepatocyte growth factor activator zymogen (pro-HGFA) by human kallikrein 1-related peptidases.
Neoplasms
Activation of human meprin-alpha in a cell culture model of colorectal cancer is triggered by the plasminogen-activating system.
Neoplasms
Activation of matrix metalloproteinase-2 (MMP-2) by membrane type 1 matrix metalloproteinase through an artificial receptor for proMMP-2 generates active MMP-2.
Neoplasms
Activation of pro-uPA is critical for initial escape from the primary tumor and hematogenous dissemination of human carcinoma cells.
Neoplasms
Activation of the epidermal growth factor signalling pathway by tissue plasminogen activator in pancreas cancer cells.
Neoplasms
Active-site MMP-selective antibody inhibitors discovered from convex paratope synthetic libraries.
Neoplasms
Activity and stability of human kallikrein-2-specific linear and cyclic peptide inhibitors.
Neoplasms
Activity of chromatin-bound protease in histone fractions from rat liver and Morris hepatoma.
Neoplasms
Activity, expression, and transcription rate of the cathepsins B, D, H, and L in cutaneous malignant melanoma.
Neoplasms
ADAM-12 as a Diagnostic Marker for the Proliferation, Migration and Invasion in Patients with Small Cell Lung Cancer.
Neoplasms
ADAM-17 is expressed in the inflammatory myopathy and is involved with interstitial lung disease.
Neoplasms
ADAM-17 over-expression in gallbladder carcinoma correlates with poor prognosis of patients.
Neoplasms
ADAM17 selectively activates the IL-6 trans-signaling/ERK MAPK axis in KRAS-addicted lung cancer.
Neoplasms
ADAM9-Responsive Mesoporous Silica Nanoparticles for Targeted Drug Delivery in Pancreatic Cancer.
Neoplasms
ADAMTS-1 disrupts HGF/c-MET signaling and HGF-stimulated cellular processes in fibrosarcoma.
Neoplasms
ADAMTS1 contributes to the acquisition of an endothelial-like phenotype in plastic tumor cells.
Neoplasms
ADAMTS1 Promotes Adhesion to Extracellular Matrix Proteins and Predicts Prognosis in Early Stage Breast Cancer Patients.
Neoplasms
ADAMTS1 protease is required for a balanced immune cell repertoire and tumour inflammatory response.
Neoplasms
ADAMTS1 Supports Endothelial Plasticity of Glioblastoma Cells with Relevance for Glioma Progression.
Neoplasms
Adeno-associated virus 2-mediated intratumoral prostate cancer gene therapy: long-term maspin expression efficiently suppresses tumor growth.
Neoplasms
Adenovirus E1A represses protease gene expression and inhibits metastasis of human tumor cells.
Neoplasms
Adhesion and protease activity in cell lines from human salivary gland tumors are regulated by the laminin-derived peptide AG73, syndecan-1 and beta1 integrin.
Neoplasms
Adipsin, the adipocyte serine protease: gene structure and control of expression by tumor necrosis factor.
Neoplasms
Adrenocortical carcinoma. An immunohistochemical comparison with renal cell carcinoma.
Neoplasms
Aging splenocyte and thymocyte apoptosis is associated with enhanced expression of p53, bax, and caspase-3.
Neoplasms
Aging-related early changes in markers of ventricular and matrix remodeling after reperfused ST-segment elevation myocardial infarction in the canine model: effect of early therapy with an angiotensin II type 1 receptor blocker.
Neoplasms
Akt phosphorylation of mitochondrial Lonp1 protease enables oxidative metabolism and advanced tumor traits.
Neoplasms
Alantolactone induces cell apoptosis partially through down-regulation of testes-specific protease 50 expression.
Neoplasms
Albumin-binding prodrugs of camptothecin and doxorubicin with an Ala-Leu-Ala-Leu-linker that are cleaved by cathepsin B: synthesis and antitumor efficacy.
Neoplasms
Allelic imbalance of 12q22-23 associated with APAF-1 locus correlates with poor disease outcome in cutaneous melanoma.
Neoplasms
Allosteric Regulation of Serine Protease HtrA2 through Novel Non-Canonical Substrate Binding Pocket.
Neoplasms
Alpha 1-antitrypsin and protease complexation is induced by lipopolysaccharide, interleukin-1beta, and tumor necrosis factor-alpha in monocytes.
Neoplasms
Alpha 1-antitrypsin, alpha 1-antichymotrypsin, and alpha 2-macroglobulin in human gastric carcinomas: a retrospective immunohistochemical study.
Neoplasms
alpha(v)beta(3) integrin engagement modulates cell adhesion, proliferation, and protease secretion in human lymphoid tumor cells.
Neoplasms
Alpha-1-antichymotrypsin expression in lung adenocarcinoma and its possible association with tumor progression.
Neoplasms
Alpha-1-antichymotrypsin immunoreactivity in papillary carcinoma of the thyroid gland.
Neoplasms
Aminopeptidase M and dipeptidyl peptidase IV activity in epithelial skin tumors: a histochemical study.
Neoplasms
Amplification of arachidonic acid metabolism in rat liver cells (the C-9 cell-line) by tosyl-L-phenylalanine chloromethyl ketone and phenylmethyl-sulfonyl fluoride.
Neoplasms
Amplification of chromosome 21q22.3 harboring trefoil factor family genes in liver fluke related cholangiocarcinoma is associated with poor prognosis.
Neoplasms
Amplification of the Urokinase-Type Plasminogen Activator Receptor (uPAR) Gene in Ductal Pancreatic Carcinomas Identifies a Clinically High-Risk Group.
Neoplasms
Amplified and label-free electrochemical detection of a protease biomarker by integrating proteolysis-triggered transcription.
Neoplasms
An aggressive desmoid tumor in a patient with familial adenomatous polyposis: immunohistochemical findings.
Neoplasms
An allosteric anti-hepsin antibody derived from a constrained phage display library.
Neoplasms
An artemisinin-mediated ROS evolving and dual protease light-up nanocapsule for real-time imaging of lysosomal tumor cell death.
Neoplasms
An ataxia telangiectasia model: inefficient cell differentiation and possible reversal by serine protease inhibitors, tumor necrosis factor inhibitors, dexamethasone, and glutathione enhancers.
Neoplasms
An emerging role for the nuclear localization of maspin in the suppression of tumor progression and metastasis (1) (1) This article is part of Special Issue entitled Asilomar Chromatin and has undergone the Journal's usual peer review process.
Neoplasms
An epigenetic genome-wide screen identifies SPINT2 as a novel tumor suppressor gene in pediatric medulloblastoma.
Neoplasms
An exo-cell assay for examining real-time gamma-secretase activity and inhibition.
Neoplasms
An innate host response to the neoplastic cell: syngeneic rat tumor cells can elicit a rapid de novo lymphoid procoagulant response.
Neoplasms
An introduction to matrikines: extracellular matrix-derived peptides which regulate cell activity. Implication in tumor invasion.
Neoplasms
An inverse correlation between expression of NCAM-A and the matrix-metalloproteinases gelatinase-A and gelatinase-B in human glioma cells in vitro.
Neoplasms
An upregulation of SENP3 after spinal cord injury: implications for neuronal apoptosis.
Neoplasms
Analysis of deubiquitinase OTUD5 as a biomarker and therapeutic target for cervical cancer by bioinformatic analysis.
Neoplasms
Analysis of genes expressed during porcine fetal pituitary development by suppressive subtraction hybridization.
Neoplasms
Analysis of the substrate specificity of Factor VII activating protease (FSAP) and design of specific and sensitive peptide substrates.
Neoplasms
Anchorage-independent growth-conferring factor production by rat mammary tumor cells.
Neoplasms
Androgen-Induced TMPRSS2 Activates Matriptase and Promotes Extracellular Matrix Degradation, Prostate Cancer Cell Invasion, Tumor Growth, and Metastasis.
Neoplasms
Androgen-induced TOP2B-mediated double-strand breaks and prostate cancer gene rearrangements.
Neoplasms
Another biological effect of tosylphenylalanylchloromethane (TPCK): it prevents p47phox phosphorylation and translocation upon neutrophil stimulation.
Neoplasms
Anthrax lethal toxin blocks MAPK kinase-dependent IL-2 production in CD4+ T cells.
Neoplasms
Anti-angiogenesis therapy:concepts and importance of dosing schedules in clinical trials.
Neoplasms
Anti-cancer action of 4-iodo-3-nitrobenzamide in combination with buthionine sulfoximine: inactivation of poly(ADP-ribose) polymerase and tumor glycolysis and the appearance of a poly(ADP-ribose) polymerase protease.
Neoplasms
Anti-cancer activity of the novel 2-hydroxydiarylamide derivatives IMD-0354 and KRT1853 through suppression of cancer cell invasion, proliferation, and survival mediated by TMPRSS4.
Neoplasms
Anti-inflammatory actions of serine protease inhibitors containing the Kunitz domain.
Neoplasms
Anti-intoxication and protective effects of a recombinant serine protease inhibitor from Lentinula edodes against acute alcohol-induced liver injury in mice.
Neoplasms
Anti-invasive activity of synthetic serine protease inhibitors and its combined effect with a matrix metalloproteinase inhibitor.
Neoplasms
Anti-invasive and Anti-tumor Effects of Dryopteris crassirhizoma Extract by Disturbing Actin Polymerization.
Neoplasms
Anti-tumour/metastasis effects of the potassium-sparing diuretic amiloride: An orally active anti-cancer drug waiting for its call-of-duty?
Neoplasms
Antibodies neutralizing hepsin protease activity do not impact cell growth but inhibit invasion of prostate and ovarian tumor cells in culture.
Neoplasms
Antibodies to the 70 kDa heat shock protein in midtrimester amniotic fluid and intraamniotic immunity.
Neoplasms
Anticancer activities of emetine prodrugs that are proteolytically activated by the prostate specific antigen (PSA) and evaluation of in vivo toxicity of emetine derivatives.
Neoplasms
Antimetastatic activity of a synthetic serine protease inhibitor, FOY-305 (Foypan).
Neoplasms
Antimetastatic activity of boro-amino acid analog protease inhibitors against B16BL6 melanoma in vivo.
Neoplasms
Antimicrobial peptide levels are linked to airway inflammation, bacterial colonisation and exacerbations in chronic obstructive pulmonary disease.
Neoplasms
Antiproliferative activity of Lavatera cashmeriana- protease inhibitors towards human cancer cells.
Neoplasms
Antisense Oligonucleotide Therapeutic Approach for Suppression of Ataxin-1 Expression: A Safety Assessment.
Neoplasms
Antiserum against tumor necrosis factor-alpha and a protease inhibitor reduce immune glomerular injury.
Neoplasms
Antitumor activity of ginsenoside Rd in gastric cancer via up-regulation of Caspase-3 and Caspase-9.
Neoplasms
Antitumor activity of some bacterial proteases: eradication of solid tumors in mice by intratumor injection.
Neoplasms
Antitumour effects of a protease inhibitor, nelfinavir, in hepatocellular carcinoma cancer cells.
Neoplasms
Apigenin acts on the tumor cell invasion process and regulates protease production.
Neoplasms
Application of Frontal Affinity Chromatography to Study the Biomolecular Interactions with Trypsin.
Neoplasms
Application of the 4D fingerprint method with a robust scoring function for scaffold-hopping and drug repurposing strategies.
Neoplasms
Aprotinin enhances the endogenous release of interleukin-10 after cardiac operations.
Neoplasms
Arf-induced turnover of the nucleolar nucleophosmin-associated SUMO-2/3 protease Senp3.
Neoplasms
ARF6-JIP3/4 regulate endosomal tubules for MT1-MMP exocytosis in cancer invasion.
Neoplasms
As an independent prognostic factor, USP6 promotes the invasion and metastasis of colon cancer.
Neoplasms
Assembly and selective "in synthesis" labeling of quenched fluorogenic protease substrates.
Neoplasms
Assessment of the interaction between urokinase and reactive site mutants of protein C inhibitor.
Neoplasms
Association between SNPs in Serpin gene family and risk of esophageal squamous cell carcinoma.
Neoplasms
Association of c-erbB-2 protein over-expression with high rate of cell proliferation, increased risk of visceral metastasis and poor long-term survival in breast cancer.
Neoplasms
Association of maspin expression with the high histological grade and lymphocyte-rich stroma in early-stage breast cancer.
Neoplasms
Association of trypsin expression with tumour progression and matrilysin expression in human colorectal cancer.
Neoplasms
ATP-dependent Lon protease controls tumor bioenergetics by reprogramming mitochondrial activity.
Neoplasms
Autoactivation and calpain-1-mediated shedding of hepsin in human hepatoma cells.
Neoplasms
Autocrine factors, type IV collagenase secretion and prostatic cancer cell invasion.
Neoplasms
Autocrine induction of tumor protease production and invasion by a metallothionein-regulated TGF-beta 1 (Ser223, 225).
Neoplasms
Bacillus Calmette-Guerin abrogates in vitro invasion and motility of human bladder tumor cells via fibronectin interaction.
Neoplasms
Basement membrane derived fibulin-1 and fibulin-5 function as angiogenesis inhibitors and suppress tumor growth.
Neoplasms
Bcl-2 and Bcl-XL antagonize the mitochondrial dysfunction preceding nuclear apoptosis induced by chemotherapeutic agents.
Neoplasms
Bcl-xL functions downstream of caspase-8 to inhibit Fas- and tumor necrosis factor receptor 1-induced apoptosis of MCF7 breast carcinoma cells.
Neoplasms
Beneficial effects of secretory leukocyte protease inhibitor after spinal cord injury.
Neoplasms
Beneficial role of overexpression of TFPI-2 on tumour progression in human small cell lung cancer.
Neoplasms
Bi-cell surface plasmon resonance detection of aptamer mediated thrombin capture in serum.
Neoplasms
Bikunin inhibits lipopolysaccharide-induced tumor necrosis factor alpha induction in macrophages.
Neoplasms
Biochemical and enzymatic characterization of human kallikrein 5 (hK5), a novel serine protease potentially involved in cancer progression.
Neoplasms
Biochemical aspects of the neuroprotective mechanism of PTEN-induced kinase-1 (PINK1).
Neoplasms
Biochemical characterization and N-terminomics analysis of leukolysin, the membrane-type 6 matrix metalloprotease (MMP25): chemokine and vimentin cleavages enhance cell migration and macrophase phagocytic activities.
Neoplasms
Biochemical pathways of apoptosis: nicotinamide adenine dinucleotide-deficient cells are resistant to tumor necrosis factor or ultraviolet light activation of the 24-kD apoptotic protease and DNA fragmentation.
Neoplasms
Bioconjugatable azo-based dark-quencher dyes: synthesis and application to protease-activatable far-red fluorescent probes.
Neoplasms
Bioengineered Macrophages Can Responsively Transform into Nanovesicles To Target Lung Metastasis.
Neoplasms
Bioengineering of an elastase inhibitor from Caesalpinia echinata (Brazil wood) seeds.
Neoplasms
Biological and biochemical inhibitors of the NF-kappa B/Rel proteins and cytokine synthesis.
Neoplasms
Biological and clinical characterization of paclitaxel poliglumex (PPX, CT-2103), a macromolecular polymer-drug conjugate.
Neoplasms
Biological basis of personalized anticoagulation in cancer: oncogene and oncomir networks as putative regulators of coagulopathy.
Neoplasms
Biological heterogeneity of ER-positive breast cancers in the post-menopausal population.
Neoplasms
Biology and insights into the role of cohesin protease separase in human malignancies.
Neoplasms
Biomimetic and enzyme-responsive dynamic hydrogels for studying cell-matrix interactions in pancreatic ductal adenocarcinoma.
Neoplasms
Bioprospecting endophytic fungi from Fusarium genus as sources of bioactive metabolites.
Neoplasms
Biotechnological Potential of Araucaria angustifolia Pine Nuts Extract and the Cysteine Protease Inhibitor AaCI-2S.
Neoplasms
Blockade of the granzyme B/perforin pathway through overexpression of the serine protease inhibitor PI-9/SPI-6 constitutes a mechanism for immune escape by tumors.
Neoplasms
Blocking of CDCP1 cleavage in vivo prevents Akt-dependent survival and inhibits metastatic colonization through PARP1-mediated apoptosis of cancer cells.
Neoplasms
Blocking tumor growth, invasion, and metastasis by maspin in a syngeneic breast cancer model.
Neoplasms
Bombyx mori homolog of tumor suppressor p53 is involved in apoptosis-mediated antiviral immunity of B. mori cells infected with nucleopolyhedrovirus.
Neoplasms
Both Rb and E7 are regulated by the ubiquitin proteasome pathway in HPV-containing cervical tumor cells.
Neoplasms
Both the cytosols and detergent extracts of breast cancer tissues are suited to evaluate the prognostic impact of the urokinase-type plasminogen activator and its inhibitor, plasminogen activator inhibitor type 1.
Neoplasms
Bowman-Birk protease inhibitor from soybeans enhances cisplatin-induced cytotoxicity in human mesothelioma cells.
Neoplasms
Bromelain proteases suppress growth, invasion and lung metastasis of B16F10 mouse melanoma cells.
Neoplasms
c-Met overexpression is a prognostic factor in ovarian cancer and an effective target for inhibition of peritoneal dissemination and invasion.
Neoplasms
C/EBP?/AEP Signaling Regulates the Oxidative Stress in Malignant Cancers, Stimulating the Metastasis.
Neoplasms
Calpain 2 and Src dependence distinguishes mesenchymal and amoeboid modes of tumour cell invasion: a link to integrin function.
Neoplasms
Calpain3 is expressed in a proteolitically active form in papillomavirus-associated urothelial tumors of the urinary bladder in cattle.
Neoplasms
Cancer cell structure: actin changes in tumour cells--possible mechanisms for malignant tumour formation.
Neoplasms
Cancer Cell-Derived Matrisome Proteins Promote Metastasis in Pancreatic Ductal Adenocarcinoma.
Neoplasms
Cancer cells release anaphylatoxin C5a from C5 by serine protease to enhance invasiveness.
Neoplasms
Cancer invasion and tissue remodeling--cooperation of protease systems and cell types.
Neoplasms
Cancer modeling: modern imaging applications in the generation of novel animal model systems to study cancer progression and therapy.
Neoplasms
Cancer Risk and Use of Protease Inhibitor or Nonnucleoside Reverse Transcriptase Inhibitor-Based Combination Antiretroviral Therapy: The D: A: D Study.
Neoplasms
Cancer-associated fibroblasts, a parameter of the tumor microenvironment, overcomes carcinoma-associated parameters in the prognosis of patients with mobile tongue cancer.
Neoplasms
Cancer-associated SCM-recognition, immunedefense suppression, and serine protease protection peptide. Part II. Immunedefense suppressive effects of the CRISPPs peptide.
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Cancer-associated SCM-recognition, immunedefense suppression, and serine protease protection peptide. Part III. CRISPP peptide protection of serine proteases against inhibition.
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Capillary-assisted microfluidic biosensing platform captures single cell secretion dynamics in nanoliter compartments.
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Cardamonin inhibited cell viability and tumorigenesis partially through blockade of testes-specific protease 50-mediated nuclear factor-kappaB signaling pathway activation.
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Carrageenan inhibits granzyme A-induced detachment of and interleukin-8 release from alveolar epithelial A549 cells.
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Caspase I-related protease inhibition retards the execution of okadaic acid- and camptothecin-induced apoptosis and PAI-2 cleavage, but not commitment to cell death in HL-60 cells.
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Caspase- and serine protease-dependent apoptosis by the death domain of FADD in normal epithelial cells.
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Caspase-3 activity, response to chemotherapy and clinical outcome in patients with colon cancer.
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Caspase-3 enhances lung metastasis and cell migration in a protease-independent mechanism through the ERK pathway.
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Caspase-3 inhibits the growth of breast cancer cells independent of protease activity.
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Caspase-8 deficiency induces a switch from TLR3 induced apoptosis to lysosomal cell death in neuroblastoma.
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Caspase-8: A Novel Target to Overcome Resistance to Chemotherapy in Glioblastoma.
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Catalytic cleavage of the androgen-regulated TMPRSS2 protease results in its secretion by prostate and prostate cancer epithelia.
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Catch and Release Photosensitizers: Combining Dual-Action Ruthenium Complexes with Protease Inactivation for Targeting Invasive Cancers.
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Cathepsin A knockdown decreases the proliferation and invasion of A549 lung adenocarcinoma cells.
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Cathepsin B acts as a dominant execution protease in tumor cell apoptosis induced by tumor necrosis factor.
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Cathepsin cysteine proteases are effectors of invasive growth and angiogenesis during multistage tumorigenesis.
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Cathepsin D deficiency in mammary epithelium transiently stalls breast cancer by interference with mTORC1 signaling.
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Cathepsin D maturation and its stimulatory effect on metastasis are prevented by addition of KDEL retention signal.
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Cathepsin D specifically cleaves the chemokines macrophage inflammatory protein-1 alpha, macrophage inflammatory protein-1 beta, and SLC that are expressed in human breast cancer.
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Cathepsin D, both a prognostic factor and a predictive factor for the effect of adjuvant tamoxifen in breast cancer. South Sweden Breast Cancer Group.
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Cathepsin G recruits osteoclast precursors via proteolytic activation of protease-activated receptor-1.
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Cathepsin L inactivation leads to multimodal inhibition of prostate cancer cell dissemination in a preclinical bone metastasis model.
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Cathepsin L inhibition suppresses drug resistance in vitro and in vivo: a putative mechanism.
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Cathepsin S from both tumor and tumor-associated cells promote cancer growth and neovascularization.
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Catheter-based in vivo imaging of enzyme activity and gene expression: feasibility study in mice.
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Cationized Bowman-Birk protease inhibitor as a targeted cancer chemopreventive agent.
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CCAAT-displacement protein/cut homeobox transcription factor (CUX1) represses estrogen receptor-alpha (ER-?) in triple-negative breast cancer cells and can be antagonized by muscadine grape skin extract (MSKE).
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CCL21 and IFN? recruit and activate tumor specific T cells in 3D scaffold model of breast cancer.
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CCR5 Antagonists: Comparison of Efficacy, Side Effects, Pharmacokinetics and Interactions - Review of the Literature.
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CD13 as target for tissue factor induced tumor vascular infarction in small cell lung cancer.
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CD163 as a marker of M2 macrophage, contribute to predicte aggressiveness and prognosis of Kazakh esophageal squamous cell carcinoma.
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CD26/DPPIV expression and 8-azaguanine response in T-acute lymphoblastic leukaemia cell lines in culture.
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CD87-positive tumor cells in bone marrow aspirates identified by confocal laser scanning fluorescence microscopy.
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Cell Intrinsic Deregulated ß-Catenin Signaling Promotes Expansion of Bone Marrow Derived Connective Tissue Type Mast Cells, Systemic Inflammation, and Colon Cancer.
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Cell surface glycoproteins expressed on activated human T cells induce production of interleukin-1 beta by monocytic cells: a possible role of CD69.
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Cell-Membrane-Localizing, Two-Photon Probe for Ratiometric Imaging of ?-Glutamyl Transpeptidase in Cancerous Cells and Tissues.
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Cell-type-specific repression of the maspin gene is disrupted frequently by demethylation at the promoter region in gastric intestinal metaplasia and cancer cells.
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Cellular resistance to bleomycin in Saccharomyces cerevisiae is not affected by changes in bleomycin hydrolase levels.
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CH05-10, a novel indinavir analog, is a broad-spectrum antitumor agent that induces cell cycle arrest, apoptosis, endoplasmic reticulum stress and autophagy.
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Changes in cyclic adenosine 3':5'-monophosphate-dependent protein kinases during the progression of urethan-induced mouse lung tumors.
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Characteristics of the level-of-evidence-1 disease forecast cancer biomarkers uPA and its inhibitor PAI-1.
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Characterization of a pineal region malignant rhabdoid tumor. Towards understanding brain tumor cell invasion.
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Characterization of an extracellular matrix-degrading protease derived from a highly metastatic tumor cell line.
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Characterization of downstream Ras signals that induce alternative protease-dependent invasive phenotypes.
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Characterization of F3II, a sarcomatoid mammary carcinoma cell line originated from a clonal subpopulation of a mouse adenocarcinoma.
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Characterization of naturally occurring pentacyclic triterpenes as novel inhibitors of deubiquitinating protease USP7 with anticancer activity in vitro.
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Characterization of prostate-specific antigen proteolytic activity on its major physiological substrate, the sperm motility inhibitor precursor/semenogelin I.
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Characterization of the lymphokine responsible for migration-inhibitory activity against tumor cells.
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Characterization of thrombin generation potential of leukemic and solid tumor cells by the calibrated automated thrombography.
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Chemical and biological evaluation of dipeptidyl boronic acid proteasome inhibitors for use in prodrugs and pro-soft drugs targeting solid tumors.
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Chemical and viral transformation of cultured skin fibroblasts from patients with familial polyposis coli.
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Chemical Modulation of Human Mitochondrial ClpP: Potential Application in Cancer Therapeutics.
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Chemistry-based functional proteomics: mechanism-based activity-profiling tools for ubiquitin and ubiquitin-like specific proteases.
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Chickpea (Cicer arietinum) and other plant-derived protease inhibitor concentrates inhibit breast and prostate cancer cell proliferation in vitro.
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Chromosomal events in carcinogenic initiation and promotion: implications for carcinogenicity testing and cancer prevention strategies.
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Chymase and tryptase in dog mastocytoma cells: asynchronous expression as revealed by enzyme cytochemical staining.
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Circulation of a fragment of haemoglobin alpha-chain during a pentagastrin-induced flush in patients with metastatic carcinoid tumours.
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Cleavage of E-Cadherin by Matrix Metalloproteinase-7 Promotes Cellular Proliferation in Nontransformed Cell Lines via Activation of RhoA.
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Cleavage of misfolded nuclear receptor corepressor confers resistance to unfolded protein response-induced apoptosis.
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Clinical evidence for correlation of insufficient tissue oxygen supply (hypoxia) and tumor-associated proteolysis in squamous cell carcinoma of the head and neck.
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Clinical impact of the plasminogen activation system in tumor invasion and metastasis: prognostic relevance and target for therapy.
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Clinical implications of fibroblast activation protein-? in non-small cell lung cancer after curative resection: a new predictor for prognosis.
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Clinical relevance of uPA, uPAR, PAI 1 and PAI 2 tissue expression and plasma PAI 1 level in colorectal carcinoma patients.
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Clinical significance of cathepsin D concentration in tumor cytosol of primary breast cancer.
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Clinical significance of the plasminogen activator system in relation to grade of tumor and treatment response in colorectal carcinoma patients.
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Cloning and expression of a cDNA encoding human placental protein 11, a putative serine protease with diagnostic significance as a tumor marker.
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Cloning of a new Kunitz-type protease inhibitor with a putative transmembrane domain overexpressed in pancreatic cancer.
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Co-chaperones TIMP2 and AHA1 Competitively Regulate Extracellular HSP90:Client MMP2 Activity and Matrix Proteolysis.
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Co-detection of members of the urokinase plasminogen activator system in tumour tissue and serum correlates with a poor prognosis for soft-tissue sarcoma patients.
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Co-localization of cortactin and phosphotyrosine identifies active invadopodia in human breast cancer cells.
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Co-localization of Protein Z, Protein Z-Dependent protease inhibitor and coagulation factor X in human colon cancer tissue: implications for coagulation regulation on tumor cells.
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Co?expression of peripheral olfactory receptors with SARS?CoV?2 infection mediators: Potential implications beyond loss of smell as a COVID?19 symptom.
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Coagulation Signaling through PAR1 as a Therapeutic Target in Pancreatic Ductal Adenocarcinoma.
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Coexpression of matrix metalloproteinase-7 (MMP-7) and epidermal growth factor (EGF) receptor in colorectal cancer: an EGF receptor tyrosine kinase inhibitor is effective against MMP-7-expressing cancer cells.
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Collagen-Immobilized Extracellular FRET Reporter for Visualizing Protease Activity Secreted by Living Cells.
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Collagenase-3 (MMP-13) expression in chondrosarcoma cells and its regulation by basic fibroblast growth factor.
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Collagenases (MMP-1, -8 and -13) and trypsinogen-2 in fluid from benign and malignant ovarian cysts.
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Combination of tumour-infarction therapy and chemotherapy via the co-delivery of doxorubicin and thrombin encapsulated in tumour-targeted nanoparticles.
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Combinatorial BTK and MALT1 inhibition augments killing of CD79 mutant diffuse large B cell lymphoma.
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Combinatorial protein engineering of proteolytically resistant mesotrypsin inhibitors as candidates for cancer therapy.
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Combined deletion of cathepsin protease family members reveals compensatory mechanisms in cancer.
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Combined evaluation of urokinase-type plasminogen activator and plasminogen activator inhibitor-2 expression in gastric carcinoma.
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Combined magnetic resonance and fluorescence imaging of the living mouse brain reveals glioma response to chemotherapy.
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Combined modulation of the mesangial machinery for monocyte recruitment by inhibition of NF-kappaB.
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Comment on "Endothelial Protein C Receptor (EPCR), Protease Activated Receptor-1 (PAR-1) and Their Interplay in Cancer Growth and Metastatic Dissemination" Cancers 2019, 11, 51.
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Comparative assessment of substrates and activity based probes as tools for non-invasive optical imaging of cysteine protease activity.
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Comparative studies on antibody and lectin-dependent macrophage-mediated tumor lysis.
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Comparison of estrogen receptors in hormone-dependent and hormone-independent Grunder strain mouse mammary tumors.
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Comparison of gene expression profiles of gingival carcinoma Ca9-22 cells and colorectal adenocarcinoma HT-29 cells to identify potentially important mediators of SLPI-induced cell migration.
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Comparison of human glutamate carboxypeptidases II and III reveals their divergent substrate specificities.
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Comparison of the acute inflammation induced by calcium pyrophosphate dihydrate, apatite and mixed crystals in the rat air pouch model of a synovial space.
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Competitive inhibition of a tumour cell surface protease. A rapid technique for in vitro testing of selective targeting systems.
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Complementary roles in cancer prevention: protease inhibitor makes the cancer preventive peptide lunasin bioavailable.
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Complex of urokinase-type plasminogen activator with its type 1 inhibitor predicts poor outcome in 576 patients with lymph node-negative breast carcinoma.
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Complex Regulation of the Pericellular Proteolytic Microenvironment during Tumor Progression and Wound Repair: Functional Interactions between the Serine Protease and Matrix Metalloproteinase Cascades.
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Complexity of cancer protease biology: Cathepsin K expression and function in cancer progression.
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Concanavalin A hepatotoxicity in mice: tumor necrosis factor-mediated organ failure independent of caspase-3-like protease activation.
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Concentrations of insulin-like growth factor (IGF)-binding protein-3 (IGFBP-3), IGF, and IGFBP-3 protease activity in cerebrospinal fluid of children with leukemia, central nervous system tumor, or meningitis.
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Conditional Gene Targeting Reveals Cell Type-Specific Roles of the Lysosomal Protease Cathepsin L in Mammary Tumor Progression.
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Constitutive shedding of the amyloid precursor protein ectodomain is up-regulated by tumour necrosis factor-alpha converting enzyme.
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Constitutive tissue factor expression of human breast cancer cell line MCF-7 is modulated by growth factors.
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Construction of a sensitive protease sensor with DNA-peptide conjugates for single-molecule detection of multiple matrix metalloproteinases.
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Context-dependent function of the deubiquitinating enzyme USP9X in pancreatic ductal adenocarcinoma.
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Contribution of ADAMTS1 as a tumor suppressor gene in human breast carcinoma. Linking its tumor inhibitory properties to its proteolytic activity on nidogen-1 and nidogen-2.
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Controlled intracellular self-assembly of gadolinium nanoparticles as smart molecular MR contrast agents.
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Cooperation of tissue factor cytoplasmic domain and PAR2 signaling in breast cancer development.
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Coronin 1C promotes triple-negative breast cancer invasiveness through regulation of MT1-MMP traffic and invadopodia function.
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Correction to Studies of Thioamide Effects on Serine Protease Activity Enable Two-Site Stabilization of Cancer Imaging Peptides.
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Correlation between cathepsin D expression and p53 protein nuclear accumulation in oesophageal squamous cell carcinoma.
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Correlation between serum tryptase, mast cells positive to tryptase and microvascular density in colo-rectal cancer patients: possible biological-clinical significance.
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Correlation between tumor cell cytotoxicity and serine protease activity of peritoneal macrophages from mice treated with bakers' yeast mannans.
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Correlation of collagenase secretion with metastatic-colonization potential in naturally occurring murine mammary tumours.
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Correlation of serpin-protease expression by comparative analysis of real-time PCR profiling data.
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Correlation of the osteoblastic phenotype with prostate-specific antigen expression in metastatic prostate cancer: implications for paracrine growth.
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Crimean-Congo hemorrhagic fever virus-encoded ovarian tumor (OTU) protease activity is dispensable for virus RNA polymerase function.
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Critical Adjuvant Influences on Preventive Anti-Metastasis Vaccine Using a Structural Epitope Derived from Membrane Type Protease PRSS14.
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Critical protein-protein interactions within the CARMA1-BCL10-MALT1 complex: Take-home points for the cell biologist.
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CRP enhances soluble LOX-1 release from macrophages by activating TNF-{alpha} converting enzyme.
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Cryptosporidium parvum induces apoptosis in biliary epithelia by a Fas/Fas ligand-dependent mechanism.
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Crystal structure of cancer chemopreventive Bowman-Birk inhibitor in ternary complex with bovine trypsin at 2.3 A resolution. Structural basis of Janus-faced serine protease inhibitor specificity.
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Crystal structure of tissue factor in complex with antibody 10H10 reveals the signaling epitope.
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Crystals of the urokinase type plasminogen activator variant beta(c)-uPAin complex with small molecule inhibitors open the way towards structure-based drug design.
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Curcumin-targeting Pericellular Serine Protease Matriptase Role in Suppression of Prostate Cancer Cell Invasion, Tumor Growth and Metastasis.
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Current Status and Perspectives of Protease Inhibitors and Their Combination with Nanosized Drug Delivery Systems for Targeted Cancer Therapy.
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CVS-3983, a selective matriptase inhibitor, suppresses the growth of androgen independent prostate tumor xenografts.
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Cyst fluid SPINK1 may help to differentiate benign and potentially malignant cystic pancreatic lesions.
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Cystatin D Locates in the Nucleus at Sites of Active Transcription and Modulates Gene and Protein Expression.
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Cysteine Cathepsin Protease Inhibition: An update on its Diagnostic, Prognostic and Therapeutic Potential in Cancer.
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Cysteine proteinase inhibitors stefin A, stefin B, and cystatin C in sera from patients with colorectal cancer: relation to prognosis.
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Cytolytic activity of peptides derived from the Cry11Bb insecticidal toxin of B. thuringiensis subsp. medellin.
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Cytoplasmic and nuclear maspin expression in lung carcinomas: an immunohistochemical study using tissue microarrays.
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Cytoskeleton and ECM tumor mutant peptides: Increased protease sensitivities and potential consequences for the HLA class I mutant epitope reservoir.
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Cytotoxic lymphocyte granzymes trigger a target cell internal disintegration pathway leading to cytolysis and DNA breakdown.
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Cytotoxicity of bacterial proteases in various tumor cells mediated through alpha 2-macroglobulin receptor.
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Dabigatran potentiates gemcitabine-induced growth inhibition of pancreatic cancer in mice.
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Decrease in serine protease HtrA1 expression correlates with grade and recurrence in meningiomas.
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Decreased Cytoplasmic Expression of ADAMTS14 Is Correlated with Reduced Survival Rates in Oral Squamous Cell Carcinoma Patients.
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Decreased matriptase/HAI-1 ratio in advanced colorectal adenocarcinoma of Chinese patients.
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Defective expression of prohormone convertase 4 and enhanced expression of insulin-like growth factor II by pleural solitary fibrous tumor causing hypoglycemia.
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Deficient activity of von Willebrand's factor-cleaving protease in patients with disseminated malignancies.
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Definition of an immunogenic region within the ovarian tumor antigen stratum corneum chymotryptic enzyme.
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Degradation of DNA topoisomerase I by a novel trypsin-like serine protease in proliferating human T lymphocytes.
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Degradation of insulin and glucagon by a factor associated with Walker 256 carcinosarcoma cells.
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Degradomics: systems biology of the protease web. Pleiotropic roles of MMPs in cancer.
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Deletion of cathepsin H perturbs angiogenic switching, vascularization and growth of tumors in a mouse model of pancreatic islet cell cancer.
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Deletions in the cytoplasmic domain of iRhom1 and iRhom2 promote shedding of the TNF receptor by the protease ADAM17.
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Delivery of a Protease-Activated Cytolytic Peptide Prodrug by Perfluorocarbon Nanoparticles.
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Demonstration and characterization of zeta (zeta), a growth-related opioid receptor, in a neuroblastoma cell line.
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Demonstration in vivo that stromelysin-3 functions through its proteolytic activity.
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Deoxyribonuclease treatment prevents blood-borne liver metastasis of cutaneously transplanted tumour cells in mice.
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Deregulation of the signaling pathways controlling urokinase production. Its relationship with the invasive phenotype.
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Desensitization of Capsaicin-Sensitive Afferents Accelerates Early Tumor Growth via Increased Vascular Leakage in a Murine Model of Triple Negative Breast Cancer.
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Design and synthesis of a pro-drug of vinblastine targeted at treatment of prostate cancer with enhanced efficacy and reduced systemic toxicity.
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Design and synthesis of fluorogenic substrate-based probes for detecting Cathepsin B activity.
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Design of novel and selective inhibitors of urokinase-type plasminogen activator with improved pharmacokinetic properties for use as antimetastatic agents.
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Design, synthesis, and anti-tumor activities of novel Brevinin-1BYa peptidomimetics.
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Design, Synthesis, and Antitumor Activities Study of Stapled A4K14-Citropin 1.1 Peptides.
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Design, synthesis, and biological evaluation of a dual tumor-specific motive containing integrin-targeted plasmin-cleavable doxorubicin prodrug.
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Design, synthesis, biochemical studies, cellular characterization, and structure-based computational studies of small molecules targeting the urokinase receptor.
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Detection of Cancer-Specific Proteases Using Magnetic Relaxation of Peptide-Conjugated Nanoparticles in Biological Environment.
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Detection of oral squamous cell carcinoma metastasis with cathepsin D: An immunohistochemical approach.
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Detection of pancreatic cancer tumours and precursor lesions by cathepsin E activity in mouse models.
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Detection of the receptor for the human urokinase-type plasminogen activator using fluoresceinated uPA.
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Determining the molecular drivers of species-specific interferon-stimulated gene product 15 interactions with nairovirus ovarian tumor domain proteases.
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Deubiquitinase USP9X promotes cell migration, invasion and inhibits apoptosis of human pancreatic cancer.
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Deubiquitinating enzyme 4 facilitates chemoresistance in glioblastoma by inhibiting P53 activity.
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Deubiquitinating enzyme USP33/VDU1 is required for Slit signaling in inhibiting breast cancer cell migration.
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Deubiquitinating enzyme USP46 suppresses the progression of hepatocellular carcinoma by stabilizing MST1.
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Development of a Cross-Reactive Monoclonal Antibody for Detecting the Tumor Stroma.
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Development of a human immuno-oncology therapeutic agent targeting HER2: targeted delivery of granzyme B.
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Development of a Protease Biosensor Based on a Dimerization-Dependent Red Fluorescent Protein.
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Development of biological tools to assess the role of TMPRSS4 and identification of novel tumor types with high expression of this prometastatic protein.
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Development of membrane type-1 matrix metalloproteinase-specific activatable fluorescent probe for malignant tumor detection.
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Development of selective protease inhibitors via engineering of the bait region of human ?2-macroglobulin.
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Development of tobacco smoke-induced lung tumors in mice fed Bowman-Birk protease inhibitor concentrate (BBIC).
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Developmental regulation of synthesis and dimerization of the amyloidogenic protease inhibitor cystatin C in the hematopoietic system.
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Diagnostic value of serum peptidome analyses for protease activated pathological conditions beyond cancer diagnosis.
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Different maspin functions in the lung adenocarcinoma A549 and SPC-A1 cell lines.
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Differential activity of cathepsin L in human placenta at two different stages of gestation.
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Differential effects of anticoagulants on tumor development of mouse cancer cell lines B16, K1735 and CT26 in lung.
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Differential effects of serine proteases on the migration of normal and tumor cells: implications for tumor microenvironment.
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Differential exoprotease activities confer tumor-specific serum peptidome patterns.
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Differential expression of protease-activated receptors-1 and -2 in stromal fibroblasts of normal, benign, and malignant human tissues.
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Differential gene expression in pristane-induced arthritis susceptible DA versus resistant E3 rats.
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Differential inhibition of endothelial cell proliferation and migration by urokinase subdomains: amino-terminal fragment and kringle domain.
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Differential proteome analysis of conditioned media to detect Smad4 regulated secreted biomarkers in colon cancer.
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Differential regulation of elafin in normal and tumor-derived mammary epithelial cells is mediated by CCAAT/enhancer binding protein beta.
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Differential regulation of plasminogen activators by epidermal growth factor in normal and neoplastic human urothelium.
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Differential response of premalignant epithelial cell classes to phorbol ester tumor promoters and to deoxycholic acid.
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Dimerization of Fab fragments enables ready screening of phage antibodies that affect hepatocyte growth factor/scatter factor activity on target cells.
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Dipeptidyl peptidase inhibits malignant phenotype of prostate cancer cells by blocking basic fibroblast growth factor signaling pathway.
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Dipeptidyl peptidase IV expression in cancer and stromal cells of human esophageal squamous cell carcinomas, adenocarcinomas and squamous cell carcinoma cell lines.
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Direct visualization of protease activity on cells migrating in three-dimensions.
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Directed Evolution of Protease Beacons that Enable Sensitive Detection of Endogenous MT1-MMP Activity in Tumor Cell Lines.
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Discovery of Selective Matriptase and Hepsin Serine Protease Inhibitors: Useful Chemical Tools for Cancer Cell Biology.
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Discovery, Synthesis, Pharmacological Profiling, and Biological Characterization of Brintonamides A-E, Novel Dual Protease and GPCR Modulators from a Marine Cyanobacterium.
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Disease processes may be reflected by correlations among tissue kallikrein proteases but not with proteolytic factors uPA and PAI-1 in primary ovarian carcinoma.
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Dissociation of solid tumor tissues with cold active protease for single-cell RNA-seq minimizes conserved collagenase-associated stress responses.
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Distinct encounter complexes of PAI-1 with plasminogen activators and vitronectin revealed by changes in the conformation and dynamics of the reactive center loop.
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Distinct functions of macrophage-derived and cancer cell-derived cathepsin Z combine to promote tumor malignancy via interactions with the extracellular matrix.
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Distribution of acid stable trypsin inhibitor immunoreactivity in normal and malignant human tissues.
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Divergence in Ubiquitin Interaction and Catalysis among the Ubiquitin-Specific Protease Family Deubiquitinating Enzymes.
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Diverse functions of protease receptor tissue factor in inflammation and metastasis.
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Diverse mitogenic agents induce the phosphorylation of two related 42,000-dalton proteins on tyrosine in quiescent chick cells.
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DNA Damage Response Proteins and Oxygen Modulate Prostaglandin E2 Growth Factor Release in Response to Low and High LET Ionizing Radiation.
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DNA methylation signal has a major role in the response of human breast cancer cells to the microenvironment.
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Down regulation of the tumor suppressor gene maspin in breast carcinoma is associated with a higher risk of distant metastasis.
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Down-regulated expression of SERPIN genes located on chromosome 18q21 in oral squamous cell carcinomas.
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Down-regulating overexpressed human Lon in cervical cancer suppresses cell proliferation and bioenergetics.
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Down-regulation of the de-ubiquitinating enzyme ubiquitin-specific protease 2 contributes to tumor necrosis factor-alpha-induced hepatocyte survival.
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Down-regulation of USP8 Inhibits Cholangiocarcinoma Cell Proliferation and Invasion.
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Downregulation of A disintegrin and metallopeptidase with thrombospondin motif type 1 by DNA hypermethylation in human gastric cancer.
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Downregulation of ER60 Protease Inhibits Cellular Proliferation by Inducing G1/S Arrest in Breast Cancer Cells In Vitro.
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Downregulation of SPINK13 Promotes Metastasis by Regulating uPA in Ovarian Cancer Cells.
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Downregulation of survivin expression by induction of the effector cell protease receptor-1 reduces tumor growth potential and results in an increased sensitivity to anticancer agents in human colon cancer.
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Downregulation of USP33 inhibits Slit/Robo signaling pathway and is associated with poor patient survival of glioma.
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Doxycycline Inhibits Cancer Stem Cell-Like Properties via PAR1/FAK/PI3K/AKT Pathway in Pancreatic Cancer.
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Drug-resistant human laryngeal carcinoma cells have increased levels of cathepsin B.
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Dual-Ratiometric Target-Triggered Fluorescent Probe for Simultaneous Quantitative Visualization of Tumor Microenvironment Protease Activity and pH in Vivo.
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Dysregulation in Genital Tract Soluble Immune Mediators in Postmenopausal Women Is Distinct by HIV Status.
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E-Cadherin fragments as potential mediators for peritoneal metastasis in advanced epithelial ovarian cancer.
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E. coli Membrane Vesicles as a Catalase Carrier for Long-Term Tumor Hypoxia Relief to Enhance Radiotherapy.
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Early breast cancer screening using iron/iron oxide-based nanoplatforms with sub-femtomolar limits of detection.
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Early effect of boron neutron capture therapy mediated by boronophenylalanine (BPA-BNCT) on mast cells in premalignant tissue and tumors of the hamster cheek pouch.
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Early effects of laparotomy and laparoscopy on bacterial behavior and proinflammatory cytokines on bacterial peritonitis in rats I: Escherichia coli.
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ECRG2 regulates ECM degradation and uPAR/FPRL1 pathway contributing cell invasion/migration.
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Effect of actinomycin D on the expression of herpes simplex virus-common surface antigen in cells transformed by herpes simplex virus type 2.
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Effect of Ca2+ and salt on forms of estradiol cytoplasmic receptor in human neoplastic breast tissue.
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Effect of dietary astaxanthin administration on the growth performance and innate immunity of juvenile crucian carp (Carassius auratus).
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Effect of leupeptin, a protease inhibitor, on the development of spontaneous tumors in strain A mice.
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Effect of LY287045, a thrombin/trypsin inhibitor, on thrombin and trypsin-induced aortic contraction and relaxation.
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Effect of natural protease inhibitors and a chemoattractant on tumor cell invasion in vitro.
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Effect of oral administration of protease inhibitor [N,N-dimethylcarbamoylmethyl 4-(4-guanidinobenzoyloxy)-phenylacetate] methanesulfate on the growth of 3-methylcholanthrene-induced carcinoma in mice.
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Effect of p15-associated protease from an avian RNA tumor virus on avian virus-specific polyprotein precursors.
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Effect of perioperative steroid therapy on the postoperative course of patients with oesophageal cancer.
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Effect of prostaglandin E2 on urokinase-type plasminogen activator production by human lung fibroblasts.
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Effect of protease and protease inhibitors on the adhesion of Ehrlich ascites tumour cells to plastic.
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Effect of protease inhibitors in mice treated with the hepatocarcinogen, hexachlorocyclohexane (alpha-isomer) and the bladder carcinogen, N-butyl-N-(4-hydroxybutyl)nitrosamine.
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Effect of protease treatment on the sensitivity of tumor cells to antibody-GPC killing.
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Effect of sulglycotide on the apoptotic processes associated with indomethacin-induced gastric mucosal injury.
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Effect of the Bowman-Birk inhibitor (a soy protein) on in vitro bladder neck/urethral and penile corporal smooth muscle activity.
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Effect of the cancer recognition, immunedefense suppression, and serine protease protection peptide on DNA synthesis in rat hepatocytes and human lymphocytes.
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Effect of the serine protease inhibitor N-tosyl-l-phenylalanine-chloromethyl ketone (TPCK) on MCF-7 mammary tumour cells growth and differentiation.
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Effect of tumor promoters, protease inhibitors, and repair processes on x-ray-induced sister chromatid exchanges in mouse cells.
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Effect of tumour necrosis factor-alpha on proliferation, activation and protein synthesis of rat hepatic stellate cells.
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Effect of vitamin E and human placenta cysteine peptidase inhibitor on expression of cathepsins B and L in implanted hepatoma Morris 5123 tumor model in Wistar rats.
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Effective activation of the proenzyme form of the urokinase-type plasminogen activator (pro-uPA) by the cysteine protease cathepsin L.
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Effective immunoconjugate therapy in cancer models targeting a serine protease of tumor fibroblasts.
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Effects of Alpha-Connexin Carboxyl-Terminal Peptide (aCT1) and Bowman-Birk Protease Inhibitor (BBI) on Canine Oral Mucosal Melanoma (OMM) Cells.
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Effects of an antibiotic protease inhibitor, actinonin on the growth within collagen gels of non-metastatic and metastatic mouse mammary tumors of the same origin.
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Effects of anti-inflammatory cytokine agent (FR167653) and serine protease inhibitor on warm ischemia-reperfusion injury of the liver graft.
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Effects of cathepsin D inhibitor from Vicia sativa L. seed hulls on human skin fibroblasts and breast cancer cells (in vitro studies).
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Effects of cellular transformation on expression of plasminogen activator inhibitors 1 and 2. Evidence for independent regulation.
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Effects of combined in vivo treatment of transplantable solid mammary carcinoma in wistar rats using vitamin E and cysteine peptidase inhibitors from human placenta.
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Effects of demethylating agent 5-aza-2(')-deoxycytidine and histone deacetylase inhibitor FR901228 on maspin gene expression in oral cancer cell lines.
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Effects of indinavir in a preliminary phase I study on dogs with stage III slenic hemangiosarcoma.
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Effects of native and cleaved forms of alpha1-antitrypsin on ME 1477 tumor cell functional activity.
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Effects of plasminogen activator inhibitor-1-specific RNA aptamers on cell adhesion, motility, and tube formation.
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Effects of secretory leukocyte protease inhibitor on the tumor necrosis factor-alpha production and NF-kappaB activation of lipopolysaccharide-stimulated macrophages.
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Effects of serine protease and deoxyribonuclease on intravascular tumor cell arrest in rat blood-borne lung metastasis.
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Effects of shRNA targeting maspin on invasion of gastric carcinoma SGC7901 cell line.
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Effects of synthetic peptides and protease inhibitors on the interaction of a human ovarian cancer cell line (NIH:OVCAR-3) with a reconstituted basement membrane (Matrigel).
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Effects of Tepary bean (Phaseolus acutifolius) protease inhibitor and semipure lectin fractions on cancer cells.
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Effects of the Bowman-Birk protease inhibitor on survival of fibroblasts and cancer cells exposed to radiation and cis-platinum.
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Effects of tissue fixation conditions and protease pretreatment on immunohistochemical performance of a large series of new anti-keratin monoclonal antibodies: value in oncopathology.
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Effects of tumor-expressed coagulation factors on cancer progression and venous thrombosis: is there a key factor?
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Effects of vitamin A and dexamethasone on collagen degradation in mouse mammary adenocarcinoma.
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Efficacy of different proteolytic treatments for the immunohistochemical stain of cytokeratins.
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Efficient a priori identification of drug resistant mutations using Dead-End Elimination and MM-PBSA.
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Efficient, enzyme responsive and tumor receptor targeting gelatin nanoparticles decorated with concanavalin-A for site-specific and controlled drug delivery for cancer therapy.
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EGF stimulates Cdc42-dependent translocation of SCC antigen to the plasma membrane.
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Electrical dual-sensing method for real-time quantitative monitoring of cell-secreted MMP-9 and cellular morphology during migration process.
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Electrochemical Activity Assay for Protease Analysis Using Carbon Nanofiber Nanoelectrode Arrays.
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Electrochemical sensing of human neutrophil elastase and polymorphonuclear neutrophil activity.
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Elevated levels and fragmented nature of cellular fibronectin in the plasma of gastrointestinal and head and neck cancer patients.
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Elevated levels of serum urokinase plasminogen activator predict poor prognosis in hepatocellular carcinoma after resection.
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Elevated plasminogen receptor expression occurs as a degradative phase event in cellular apoptosis.
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Elucidation of the Contribution of Active Site and Exosite Interactions to Affinity and Specificity of Peptidylic Serine Protease Inhibitors, using Non-natural Arginine Analogs.
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Emergence of metastatic hormone-refractory disease in prostate cancer after anti-androgen therapy.
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Emerging role of ubiquitin-specific protease 14 in oncogenesis and development of tumor: Therapeutic implication.
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EMMPRIN promotes angiogenesis through HIF-2{alpha} mediated regulation of soluble VEGF isoforms and their receptor VEGFR-2.
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Endogenous expression of proteases in colon cancer cells facilitate influenza A viruses mediated oncolysis.
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Endothelial derived vasoactive factors and leukocyte derived inflammatory mediators in subjects with asymptomatic atherosclerosis.
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Endothelial Protein C Receptor (EPCR), Protease Activated Receptor-1 (PAR-1) and Their Interplay in Cancer Growth and Metastatic Dissemination.
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Endothelin-1 induces tumor proteinase activation and invasiveness of ovarian carcinoma cells.
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Engineered protease inhibitors based on sunflower trypsin inhibitor-1 (SFTI-1) provide insights into the role of sequence and conformation in Laskowski mechanism inhibition.
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Engineering carboxypeptidase G2 circular permutations for the design of an autoinhibited enzyme.
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Engineering of substrate selectivity for tissue factor-factor VIIa complex signaling through protease activated receptor 2.
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Engineering potent mesotrypsin inhibitors based on the plant-derived cyclic peptide, sunflower trypsin inhibitor-1.
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Enhanced activity of meprin-?, a pro-migratory and pro-angiogenic protease, in colorectal cancer.
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Enhancement of DNA vaccine potency by coadministration of a tumor antigen gene and DNA encoding serine protease inhibitor-6.
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Enrichment of common carp (Cyprinus carpio) diet with medlar (Mespilus germanica) leaf extract: Effects on skin mucosal immunity and growth performance.
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Ensnaring membrane type 1-matrix metalloproteinase (MT1-MMP) with tissue inhibitor of metalloproteinase (TIMP)-2 using the haemopexin domain of the protease as a carrier: a targeted approach in cancer inhibition.
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Enzyme activity profiles of the secreted and membrane proteome that depict cancer cell invasiveness.
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Enzyme leakage, trypsinogen activation, and inflammatory response in endoscopic retrograde cholangiopancreatography-induced pancreatitis.
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Enzyme-activatable imaging probe reveals enhanced neutrophil elastase activity in tumors following photodynamic therapy.
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Enzyme-induced aggregation and disaggregation of tumor cells via the cell surface glycocalyx in association with deoxyribonucleic acid.
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Epidermal growth factor and pro-inflammatory cytokines regulate the expression of components of plasminogen activation system in U373-MG astrocytoma cells.
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Epigenetic inactivation of the candidate tumor suppressor USP44 is a frequent and early event in colorectal neoplasia.
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Epigenetic silencing of PRSS3 provides growth and metastasis advantage for human hepatocellular carcinoma.
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Epigenetic silencing of the PRSS3 putative tumor suppressor gene in non-small cell lung cancer.
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Epigenetic silencing of the putative tumor suppressor gene testisin in testicular germ cell tumors.
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Epitope-based immunoinformatics and molecular docking studies of nucleocapsid protein and ovarian tumor domain of crimean-congo hemorrhagic Fever virus.
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ERMP1, a novel potential oncogene involved in UPR and oxidative stress defense, is highly expressed in human cancer.
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Establishment and validation of computational model for MT1-MMP dependent ECM degradation and intervention strategies.
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Establishment of a new human cancer cell line secreting protease nexin-II/amyloid beta protein precursor derived from squamous-cell carcinoma of lung.
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Estradiol selectively regulates innate immune function by polarized human uterine epithelial cells in culture.
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Estrogen regulated proteases and antiproteases in ovarian and breast cancer cells.
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Estrogen-induced lysosomal proteases secreted by breast cancer cells: a role in carcinogenesis?
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Etravirine: a good option for concomitant use with chemotherapy for Hodgkin's lymphoma.
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Ets-1 positively regulates expression of urokinase-type plasminogen activator (uPA) and invasiveness of astrocytic tumors.
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Evaluating the role of serine protease inhibition in the management of tumor micrometastases.
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Evaluation of an automated chemiluminescent immunoassay for complexed PSA on the Bayer ACS:180 system.
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Evidence for a direct interaction between the tumor suppressor serpin, maspin, and types I and III collagen.
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Evidence for a role of a tumor necrosis factor-alpha (TNF-alpha)-converting enzyme-like protease in shedding of TRANCE, a TNF family member involved in osteoclastogenesis and dendritic cell survival.
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Evidence for the functional similarity between tumour cell surface guanidinobenzoatase and tissue type plasminogen activator.
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Evidence for the induction of protease activity on cultured tumour cells as a consequence of implantation into nude mice.
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Evidence for the presence of a trypsin inhibitor within rabbit and mouse tumour cells.
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Evidence for the requirement of proteolysis in LH stimulated cyclic AMP production and steroidogenesis in Leydig cells.
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Evidence of post-translational modification of the tumor suppressor maspin under oxidative stress.
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Evidence that elastase is the TNF-R75 shedding enzyme in resting human polymorphonuclear leukocytes.
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Exercise ameliorates insulin resistance via regulating TGF?-activated kinase 1 (TAK1)-mediated insulin signaling in liver of high-fat diet-induced obese rats.
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Experimental and Clinical Evidence Supports the Use of Urokinase Plasminogen Activation System Components as Clinically Relevant Biomarkers in Gastroesophageal Adenocarcinoma.
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Experimental models of invasion and metastasis; can they provide reliable answers for the role of proteases in cancer?
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Exploiting proteases for cancer theranostic through molecular imaging and drug delivery.
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Expression analysis of maspin in invasive ductal carcinoma of breast and modulation of its expression by curcumin in breast cancer cell lines.
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Expression analysis of the estrogen receptor target genes in renal cell carcinoma.
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Expression and activity analysis of a new fusion protein targeting ovarian cancer cells.
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Expression and clinical significance of ubiquitin?specific?processing protease 34 in diffuse large B?cell lymphoma.
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Expression and functional analyses of mHAUSP regulating apoptosis of cervical adenocarcinoma cells.
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Expression and localization of maspin in cervical cancer and its role in tumor progression and lymphangiogenesis.
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Expression and prognostic significance of kallikrein-related peptidase 8 protein levels in advanced ovarian cancer by using automated quantitative analysis.
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Expression and regulation of tumor suppressor gene maspin in human bladder cancer.
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Expression and role of the cell surface protease seprase/fibroblast activation protein-? (FAP-?) in astroglial tumors.
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Expression of ?v?6 integrin and collagen fibre in oral squamous cell carcinoma: association with clinical outcomes and prognostic implications.
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Expression of ADAMs (a disintegrin and metalloproteases) and TIMP-3 (tissue inhibitor of metalloproteinase-3) in human prostatic adenocarcinomas.
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Expression of aminopeptidase-n (CD 13) in normal tissues and malignant neoplasms of epithelial and lymphoid origin.
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Expression of c-ets-1, collagenase 1, and urokinase-type plasminogen activator genes in lung carcinomas.
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Expression of cathepsin D, stromelysin-3, and urokinase by reactive stromal cells on breast carcinoma prognosis.
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Expression of CCCTC-binding factor (CTCF) is linked to poor prognosis in prostate cancer.
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Expression of CD133 confers malignant potential by regulating metalloproteinases in human hepatocellular carcinoma.
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Expression of cellular FLICE inhibitory protein, caspase-8, and protease inhibitor-9 in Ewing sarcoma and implications for susceptibility to cytotoxic pathways.
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Expression of Fibroblast Activating Protein and Correlation with Histological Grade, Mitotic Index and Ki67 Expression in Canine Mast Cell Tumours.
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Expression of HAUSP in gliomas correlates with disease progression and survival of patients.
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Expression of Hepatocyte Growth Factor Activator Inhibitor Type 1 in Human Hepatocellular Carcinoma and Postoperative Outcomes.
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Expression of insulin-like growth factor binding protein genes and its hypoxic regulation in U87 glioma cells depends on ERN1 mediated signaling pathway of endoplasmic reticulum stress.
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Expression of inter-alpha-trypsin inhibitor and tumor necrosis factor-stimulated gene 6 in renal proximal tubular epithelial cells.
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Expression of Maspin in non-muscle invasive bladder carcinoma: correlation with tumor angiogenesis and prognosis.
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Expression of maspin in non-small cell lung cancer and its relationship to vasculogenic mimicry.
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Expression of maspin in non-small-cell lung cancer: correlation with clinical features.
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Expression of OTUB1 in hepatocellular carcinoma and its effects on HCC cell migration and invasion.
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Expression of p16 in lymph node metastases of adjuvantly treated stage III colorectal cancer patients identifies poor prognostic subgroups: a retrospective analysis of biomarkers in matched primary tumor and lymph node metastases.
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Expression of plasminogen activator inhibitors type 1 and type 3 and urokinase plasminogen activator protein and mRNA in breast cancer.
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Expression of prostasin and its inhibitors during colorectal cancer carcinogenesis.
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Expression of prostate-specific antigen (PSA) correlates with poor response to tamoxifen therapy in recurrent breast cancer.
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Expression of protease activated receptor-2 in human colorectal cancer and its association with tumor progression.
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Expression of protease activated receptor-2 is reduced in renal cell carcinoma biopsies and cell lines.
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Expression of protease activated receptor-2 related to angiogenesis in tumor advancement of uterine endometrial cancers.
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Expression of protein C inhibitor (PCI) in benign and malignant prostatic tissues.
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Expression of serine protease matriptase in renal cell carcinoma: correlation of tissue microarray immunohistochemical expression analysis results with clinicopathological parameters.
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Expression of serine protease SNC19/matriptase and its inhibitor hepatocyte growth factor activator inhibitor type 1 in normal and malignant tissues of gastrointestinal tract.
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Expression of Snail, Slug and Sip1 in malignant mesothelioma effusions is associated with matrix metalloproteinase, but not with cadherin expression.
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Expression of the apoptosis inhibitor protease inhibitor 9 predicts clinical outcome in vaccinated patients with stage III and IV melanoma.
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Expression of the granzyme B inhibitor, protease inhibitor 9, by tumor cells in patients with non-Hodgkin and Hodgkin lymphoma: a novel protective mechanism for tumor cells to circumvent the immune system?
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Expression of the human urokinase-type plasminogen activator receptor in E. coli and Chinese hamster ovary cells: purification of the recombinant proteins and generation of polyclonal antibodies in chicken.
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Expression of the immune modulator secretory leukocyte protease inhibitor (SLPI) in colorectal cancer liver metastases and matched primary tumors is associated with a poorer prognosis.
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Expression of the p53 and Maspin protein in primary prostate cancer: correlation with clinical features.
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Expression of the protease inhibitor antileukoprotease and the serine protease stratum corneum chymotryptic enzyme (SCCE) is coordinated in ovarian tumors.
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Expression of the serine protease matriptase and its inhibitor HAI-1 in epithelial ovarian cancer: correlation with clinical outcome and tumor clinicopathological parameters.
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Expression of the serpin centerin defines a germinal center phenotype in B-cell lymphomas.
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Expression of the TGF alpha integral membrane precursor induces transformation of NRK cells.
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Expression of tissue factor by melanoma cells promotes efficient hematogenous metastasis.
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Expression of tissue factor in tumor stroma correlates with progression to invasive human breast cancer: paracrine regulation by carcinoma cell-derived members of the transforming growth factor beta family.
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Expression of Tissue Factor Pathway Inhibitor 2 in Human Pancreatic Carcinoma and its Effect on Tumor Growth, Invasion, and Migration in vitro and in vivo.
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Expression of tissue factor pathway inhibitor 2 inversely correlates during the progression of human gliomas.
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Expression of TMPRSS4 in non-small cell lung cancer and its modulation by hypoxia.
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Expression of tumor necrosis factor alpha and matrix metalloproteinase-9 in surgically induced necrotizing scleritis.
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Expression of USP22 and Survivin is an indicator of malignant behavior in hepatocellular carcinoma.
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Expression of USP22 and the chromosomal passenger complex is an indicator of malignant progression in oral squamous cell carcinoma.
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Expression Status of Serine Protease 27: A Prognostic Marker for Esophageal Squamous Cell Carcinoma Treated with Preoperative Chemotherapy/Chemoradiotherapy.
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Expressions of Tumor Necrosis Factor alpha-induced Protein 3 and Mammary Serine Protease Inhibitor in Radiotherapy of Nasopharyngeal Carcinoma.
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Extracellular binding of indinavir to matrix metalloproteinase-2 and the alpha-7-nicotinic acetylcholine receptor: implications for use in cancer treatment.
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Extracellular Granzyme A Promotes Colorectal Cancer Development by Enhancing Gut Inflammation.
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Extracellular matrix protein fibronectin induces matrix metalloproteinases in human prostate adenocarcinoma cells PC-3.
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Extracellular matrix protein laminin induces matrix metalloproteinase-9 in human breast cancer cell line mcf-7.
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Extracellular matrix remodeling: the common denominator in connective tissue diseases possibilities for evaluation and current understanding of the matrix as more than a passive architecture, but a key player in tissue failure.
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Extracellular matrix signature identifies breast cancer subgroups with different clinical outcome.
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Extracellular Protease ADAMTS1 Is Required at Early Stages of Human Uveal Melanoma Development by Inducing Stemness and Endothelial-Like Features on Tumor Cells.
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Extracellular protease ADAMTS9 suppresses esophageal and nasopharyngeal carcinoma tumor formation by inhibiting angiogenesis.
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Extracellular protease imaging for cell mass tracking of xenografted human malignant pleural mesothelioma.
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Extracellular proteolytic cleavage by urokinase is required for activation of hepatocyte growth factor/scatter factor.
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Extracellular sphingomyelinase activity impairs TNF-?-induced endothelial cell death via ADAM17 activation and TNF receptor 1 shedding.
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Factors predictive of disease progression and death in AIDS-related Kaposi's sarcoma.
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FAM105A/OTULINL Is a Pseudodeubiquitinase of the OTU-Class that Localizes to the ER Membrane.
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Familial polyposis coli plasma causes a transformation-associated morphology of cells in vitro: hyperproteinemia and colorectal polyps.
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FAPalpha, a surface peptidase expressed during wound healing, is a tumor suppressor.
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Fas- and tumor necrosis factor-induced apoptosis is inhibited by the poxvirus crmA gene product.
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Feasibility and Therapeutic Potential of 177Lu-Fibroblast Activation Protein Inhibitor-46 for Patients With Relapsed or Refractory Cancers: A Preliminary Study.
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Fem1b, a proapoptotic protein, mediates proteasome inhibitor-induced apoptosis of human colon cancer cells.
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Ferri-liposomes as an MRI-visible drug-delivery system for targeting tumours and their microenvironment.
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Fibrin formation induced by tumor procoagulants enhances urokinase activity produced by mammary carcinoma cells.
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Fibrinolytic activity in a human fibrosarcoma cell line and evidence for the induction of plasminogen activator secretion during tumor formation.
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Fibroblast activation protein (FAP) is upregulated in myelomatous bone and supports myeloma cell survival.
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Fibroblast Activation Protein ?-Targeted CD40 Agonism Abrogates Systemic Toxicity and Enables Administration of High Doses to Induce Effective Antitumor Immunity.
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Fibroblast activation protein alpha is expressed by transformed and stromal cells and is associated with mesenchymal features in glioblastoma.
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Fibroblast Activation Protein Expressing Mesenchymal Cells Promote Glioblastoma Angiogenesis.
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Fibroblast activation protein increases metastatic potential of fibrosarcoma line HT1080 through upregulation of integrin-mediated signaling pathways.
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Fibroblast activation protein is expressed by rheumatoid myofibroblast-like synoviocytes.
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Fibroblast activation protein peptide substrates identified from human collagen I derived gelatin cleavage sites.
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Fibroblast activation protein, a dual specificity serine protease expressed in reactive human tumor stromal fibroblasts.
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Fibroblast activation protein-? in fibrogenic disorders and cancer: more than a prolyl-specific peptidase?
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Fibroblast activation protein-? in tumor cells promotes colorectal cancer angiogenesis via the Akt and ERK signaling pathways.
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Fibroblast activation protein-?: a key modulator of the microenvironment in multiple pathologies.
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Fibroblast activation protein: differential expression and serine protease activity in reactive stromal fibroblasts of melanocytic skin tumors.
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Fibroblast activation proteins-? suppress tumor immunity by regulating T cells and tumor-associated macrophages.
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Field bean protease inhibitor preparations, unlike methotrexate, can completely suppress Yoshida sarcoma tumor in rats.
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Flipping the substrate preference of Hazara virus ovarian tumour domain protease through structure-based mutagenesis.
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Formulation and Evaluation of Isradipine Nanosuspension and Exploring its Role as a Potential Anticancer Drug by Computational Approach.
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Fragments generated upon extracellular matrix remodeling: Biological regulators and potential drugs.
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Frailty phenotype is associated with antiretroviral exposure among older persons living with HIV.
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Free oxygen radicals: necessary contributors to tumor promotion and cocarcinogenesis.
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Fsn0503h antibody-mediated blockade of cathepsin S as a potential therapeutic strategy for the treatment of solid tumors.
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Function and clinical relevance of kallikrein-related peptidases and other serine proteases in gynecological cancers.
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Functional analysis of HGF/MET signaling and aberrant HGF-activator expression in diffuse large B-cell lymphoma.
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Functional profiling of circulating tumor cells with an integrated vortex capture and single-cell protease activity assay.
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Further inhibition studies on guanidinobenzoatase, a trypsin-like enzyme associated with tumour cells.
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Fusion of [(18)F]FDG PET with Fluorescence Diffuse Optical Tomography to Improve Validation of Probes and Tumor Imaging.
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Gabexate mesilate, a synthetic protease inhibitor, attenuates endotoxin-induced pulmonary vascular injury by inhibiting tumor necrosis factor production by monocytes.
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Gabexate mesilate, a synthetic protease inhibitor, inhibits lipopolysaccharide-induced tumor necrosis factor-alpha production by inhibiting activation of both nuclear factor-kappaB and activator protein-1 in human monocytes.
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Gamma linolenic acid regulates expression of maspin and the motility of cancer cells.
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Gelsolin-Cu/ZnSOD interaction alters intracellular reactive oxygen species levels to promote cancer cell invasion.
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Gene expression profile of A549 cells from tissue of 4D model predicts poor prognosis in lung cancer patients.
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Gene expression profiles in cells transformed by overexpression of the IGF-I receptor.
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Gene expression profiling by DNA microarray analysis in mouse embryonic fibroblasts transformed by rasV12 mutated protein and the E1A oncogene.
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Gene expression profiling reveals molecular marker candidates of laryngeal squamous cell carcinoma.
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Generation of tumoricidal effector cells with a novel potentiator: N-[4-[(4-fluorophenyl)sulfonyl]phenyl] acetamide (CL 259,763).
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Genes encoding tumor necrosis factor alpha and granzyme A are expressed during development of autoimmune diabetes.
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Genetic downregulation of pregnancy-associated plasma protein-A (PAPP-A) by bikunin reduces IGF-I-dependent Akt and ERK1/2 activation and subsequently reduces ovarian cancer cell growth, invasion and metastasis.
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Genetically Encoded Fluorescent Biosensors for Live-Cell Imaging of MT1-MMP Protease Activity.
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Genetically-engineered protein prodrug-like nanoconjugates for tumor-targeting biomimetic delivery via a SHEATH strategy.
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Genomic analysis of low-grade serous ovarian carcinoma to identify key drivers and therapeutic vulnerabilities.
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Geometry of the simian virus 40 large tumor antigen-DNA complex as probed by protease digestion.
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Ginger DNA transposons in eukaryotes and their evolutionary relationships with long terminal repeat retrotransposons.
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Global gene expression profile of nasopharyngeal carcinoma by laser capture microdissection and complementary DNA microarrays.
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Global Protease Activity Profiling Identifies HER2-Driven Proteolysis in Breast Cancer.
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Global Protease Activity Profiling Provides Differential Diagnosis of Pancreatic Cysts.
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Glucan stimulates production of antitumor cytolytic/cytostatic factor(s) by macrophages.
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Glycosaminoglycan-sac formation in vitro. Interactions between normal and malignant cells.
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Gold Nanoparticles and Graphene Oxide Flakes Enhance Cancer Cells' Phagocytosis through Granzyme-Perforin-Dependent Biomechanism.
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Gold nanoparticles based molecular beacons for in vitro and in vivo detection of the matriptase expression on tumor.
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GPDPLQ1237-A Type II Collagen Neo-Epitope Biomarker of Osteoclast- and Inflammation-Derived Cartilage Degradation in vitro.
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Granule-associated serine proteases: granzymes might not just be killer proteases.
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Granzyme B Functionalized Nanoparticles Targeting Membrane Hsp70-Positive Tumors for Multimodal Cancer Theranostics.
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Granzyme B in Inflammatory Diseases: Apoptosis, Inflammation, Extracellular Matrix Remodeling, Epithelial-to-Mesenchymal Transition and Fibrosis.
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Granzyme B Is a Biomarker For Suspicion of Malignant Seromas Around Breast Implants.
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Granzyme M as a novel effector molecule for human cytolytic fusion proteins: CD64-specific cytotoxicity of Gm-H22(scFv) against leukemic cells.
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Growth inhibition of mouse autochthonous skin cancer by oral administration of new serine protease inhibitor ONO-3403.
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HAI-2 is epigenetically downregulated in human hepatocellular carcinoma, and its Kunitz domain type 1 is critical for anti-invasive functions.
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HATL5: A Cell Surface Serine Protease Differentially Expressed in Epithelial Cancers.
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Heat shock cognate 70 protein secretion as a new growth arrest signal for cancer cells.
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Hemagglutinin protease secreted by V. cholerae induced apoptosis in breast cancer cells by ROS mediated intrinsic pathway and regresses tumor growth in mice model.
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Hemocompatible LAT1-inhibitor can induce apoptosis in cancer cells without affecting brain amino acid homeostasis.
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Heparanase stimulation of protease expression implicates it as a master regulator of the aggressive tumor phenotype in myeloma.
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Heparinoids Activate a Protease, Secreted by Mucosa and Tumors, via Tethering Supplemented by Allostery.
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Hepatic natural killer cells exclusively kill splenic/blood natural killer-resistant tumor cells by the perforin/granzyme pathway.
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Hepatocyte growth factor activation inhibitors (HAI-1 and HAI-2) regulate HGF-induced invasion of human breast cancer cells.
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Hepsin and maspin are inversely expressed in laser capture microdissectioned prostate cancer.
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Hepsin, a cell surface serine protease identified in hepatoma cells, is overexpressed in ovarian cancer.
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HHV8 and Kaposi's sarcoma: should we really give up protease inhibitors in all HIV-infected patients?
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High expression of maspin is associated with early tumor relapse in breast cancer.
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High expression of PPM1G is associated with the progression and poor prognosis of hepatocellular carcinoma.
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High Expression of PRSS3 Indicates Unfavorable Clinical Outcomes in Colon Adenocarcinoma.
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High expression of ubiquitin carboxyl-terminal hydrolase 22 is associated with poor prognosis in hepatitis B virus-associated liver cancer.
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High Expression of Ubiquitin-Specific Protease 8 (USP8) Is Associated with Poor Prognosis in Patients with Cervical Squamous Cell Carcinoma.
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High frequency of coexpression of maspin with p63 and p53 in squamous cell carcinoma but not in adenocarcinoma of the lung.
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High level synthesis of recombinant soluble urokinase receptor (CD87) by ovarian cancer cells reduces intraperitoneal tumor growth and spread in nude mice.
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High Levels of Inflammatory Cytokines in the Reproductive Tract of Women with BV and Engaging in Intravaginal Douching: A Cross-Sectional Study of Participants in the Women Interagency HIV Study.
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High SPINK1 Expression Predicts Poor Prognosis and Promotes Cell Proliferation and Metastasis of Hepatocellular Carcinoma.
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High yield synthesis and characterization of phosphorylated recombinant human procathepsin D expressed in mammalian cells.
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High-density lipoproteins protect endothelial cells from tumor necrosis factor-alpha-induced apoptosis.
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High-grade anal intraepithelial neoplasia is associated with HIV-1 RNA rectal shedding in virologically suppressed men who have sex with men.
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Highly sensitive detection of early-stage pancreatic cancer by multimodal near-infrared molecular imaging in living mice.
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Hispolon suppresses metastasis via autophagic degradation of cathepsin S in cervical cancer cells.
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HIV Protease Inhibitors Block HPV16-Induced Murine Cervical Carcinoma and Promote Vessel Normalization in Association with MMP-9 Inhibition and TIMP-3 Induction.
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HIV-1 protease inhibitors nelfinavir and atazanavir induce malignant glioma death by triggering endoplasmic reticulum stress.
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Homocysteine inhibits the proliferation and invasive potential of HT-1080 human fibrosarcoma cells.
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Homotrimeric MMP-9 is an active hitchhiker on alpha-2-macroglobulin partially escaping protease inhibition and internalization through LRP-1.
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Hormonal modulation of plasminogen activator: an approach to prediction of human breast tumor responsiveness.
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Host factors in the susceptibility of mice to tumour initiating and promoting agents.
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HT-1080 fibrosarcoma cell matrix degradation and invasion are inhibited by the matrix-associated serine protease inhibitor TFPI-2/33 kDa MSPI.
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HtrA1 Down-regulation Induces Cisplatin Resistance in Colon Cancer by Increasing XIAP and Activating PI3K/Akt Pathway.
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HTRA1 promotes transdifferentiation of normal fibroblasts to cancer-associated fibroblasts through activation of the NF-?B/bFGF signaling pathway in gastric cancer.
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Hu/Mu ProtIn oligonucleotide microarray: dual-species array for profiling protease and protease inhibitor gene expression in tumors and their microenvironment.
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Human DESC1 serine protease confers tumorigenic properties to MDCK cells and it is upregulated in tumours of different origin.
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Human Kallikrein 10 Expression in Surgically Removed Human Pituitary Corticotroph Adenomas: An Immunohistochemical Study.
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Human metalloprotease-disintegrin Kuzbanian regulates sympathoadrenal cell fate in development and neoplasia.
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Human monocyte chemotactic protein-3 (MCP-3): molecular cloning of the cDNA and comparison with other chemokines.
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Human neutrophils uniquely release TIMP-free MMP-9 to provide a potent catalytic stimulator of angiogenesis.
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Human ovarian tumor-associated trypsin. Its purification and characterization from mucinous cyst fluid and identification as an activator of pro-urokinase.
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Human tissue kallikrein 7, a novel biomarker for advanced ovarian carcinoma using a novel in situ quantitative method of protein expression.
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Human uterus myoma and gene expression profiling: A novel in vitro model for studying secretory leukocyte protease inhibitor-mediated tumor invasion.
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Humoral and cellular immune functions are not compromised by the anticarcinogenic Bowman-Birk inhibitor.
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Hybrid Small Animal Imaging System Combining Magnetic Resonance Imaging With Fluorescence Tomography Using Single Photon Avalanche Diode Detectors.
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Hydrogel Microwell Arrays Allow the Assessment of Protease-Associated Enhancement of Cancer Cell Aggregation and Survival.
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Hypermethylation and histone deacetylation lead to silencing of the maspin gene in human breast cancer.
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Hypomethylation of urokinase (uPA) promoter in breast and prostate cancer: prognostic and therapeutic implications.
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Hypoxia and RAS-signaling pathways converge on, and cooperatively downregulate, the RECK tumor-suppressor protein through microRNAs.
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Hypoxia induces epithelial-mesenchymal transition in colorectal cancer cells through ubiquitin-specific protease 47-mediated stabilization of Snail: A potential role of Sox9.
Neoplasms
Hypoxia maintains the fenestration of liver sinusoidal endothelial cells and promotes their proliferation through the SENP1/HIF-1?/VEGF signaling axis.
Neoplasms
Hypoxia negatively regulates antimetastatic PEDF in melanoma cells by a hypoxia inducible factor-independent, autophagy dependent mechanism.
Neoplasms
Hypoxia Regulates DPP4 Expression, Proteolytic Inactivation, and Shedding from Ovarian Cancer Cells.
Neoplasms
Hypoxia-inducible factor 1 regulation through cross talk between mTOR and MT1-MMP.
Neoplasms
Hypoxia-inducible factor mediates hypoxic and tumor necrosis factor alpha-induced increases in tumor necrosis factor-alpha converting enzyme/ADAM17 expression by synovial cells.
Neoplasms
Identification and analysis of mammalian KLK6 orthologue genes for prediction of physiological substrates.
Neoplasms
Identification and characterization of the cell-associated binding protein for urinary trypsin inhibitor.
Neoplasms
Identification and cloning of a novel isoform of mouse secretory leukocyte protease inhibitor, mSLPI-beta, overexpressed in murine leukemias and a highly liver metastatic tumor, IMC-HA1 cells.
Neoplasms
Identification and interaction repertoire of large forms of the basement membrane protein nidogen.
Neoplasms
Identification and preclinical testing of a reversible cathepsin protease inhibitor reveals anti-tumor efficacy in a pancreatic cancer model.
Neoplasms
Identification and quantification of proteins differentially secreted by a pair of normal and malignant breast-cancer cell lines.
Neoplasms
Identification of a myeloid-derived suppressor cell cystatin-like protein that inhibits metastasis.
Neoplasms
Identification of a novel aspartic-like protease differentially expressed in human breast cancer cell lines.
Neoplasms
Identification of a putative nuclear localization signal in the tumor suppressor maspin sheds light on its nuclear import regulation.
Neoplasms
Identification of an intrinsic determinant critical for maspin subcellular localization and function.
Neoplasms
Identification of cell surface cathepsin B-like activity on murine melanomas and fibrosarcomas: modulation by butanol extraction.
Neoplasms
Identification of collaborative activities with oxidative phosphorylation in bipolar disorder.
Neoplasms
Identification of degradome components associated with prostate cancer progression by expression analysis of human prostatic tissues.
Neoplasms
Identification of differentially expressed messenger RNAs in human melanocytes and melanoma cells.
Neoplasms
Identification of immunoreactive tissue kallikrein in human ductal breast carcinomas.
Neoplasms
Identification of inhibitory scFv antibodies targeting fibroblast activation protein utilizing phage display functional screens.
Neoplasms
Identification of key miRNA-gene pairs in gastric cancer through integrated analysis of mRNA and miRNA microarray.
Neoplasms
Identification of Kinases and Phosphatases That Regulate ATG4B Activity by siRNA and Small Molecule Screening in Cells.
Neoplasms
Identification of low-risk node-negative breast cancer patients by tumor biological factors PAI-1 and cathepsin L.
Neoplasms
Identification of nafamostat mesilate as an inhibitor of the fat mass and obesity-associated protein (FTO) demethylase activity.
Neoplasms
Identification of novel tumor suppressor proteases by degradome profiling of colorectal carcinomas.
Neoplasms
Identification of potential mitochondrial CLPXP protease interactors and substrates suggests its central role in energy metabolism.
Neoplasms
Identification of potential target genes of USP22 via ChIP-seq and RNA-seq analysis in HeLa cells.
Neoplasms
Identification of Protease Cleavage Sites and Substrates in Cancer by Carboxy-TAILS (C-TAILS).
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Identification of small molecules that sensitize resistant tumor cells to tumor necrosis factor-family death receptors.
Neoplasms
Identification, Molecular Characterization and Alternative Splicing of Three Novel Members of the Canine Kallikrein (Klk)-related Peptidase Family.
Neoplasms
IgE-mediated basophil tumour necrosis factor alpha induces matrix metalloproteinase-9 from monocytes.
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IKK? inibition by a glucosamine derivative enhances Maspin expression in osteosarcoma cell line.
Neoplasms
IL-13 regulates cancer invasion and metastasis through IL-13R?2 via ERK/AP-1 pathway in mouse model of human ovarian cancer.
Neoplasms
IL-4 induces cathepsin protease activity in tumor-associated macrophages to promote cancer growth and invasion.
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Imaging of differential protease expression in breast cancers for detection of aggressive tumor phenotypes.
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Immunohistochemical Evaluation of Hemostatic Changes in Glioblastoma Multiforme and Low-Grade Astrocytoma.
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Immunohistochemical evaluation of tissue-specific proteolytic enzymes in adenomas containing foci of early carcinoma: correlations with cathepsin D expression and other malignant features.
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Immunologic detection of the cellular receptor for urokinase plasminogen activator.
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Immunological and functional determination of the protease inhibitors, protein C and antithrombin III, in liver cirrhosis and in neoplasia.
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Immunonutritional consequences of different serine-type protease inhibitors in a C57BL/6 hepatocarcinoma model.
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Immunotherapy with SLPI over-expressing mammary tumor cells decreases tumor growth.
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Impact of Antiretroviral Therapy on the Risk of Recurrence in HIV-1 Infected Patients with Kaposi Sarcoma: A Multicenter Cohort Experience.
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Impact of Herpes Simplex Virus Type 2 and Human Immunodeficiency Virus Dual Infection on Female Genital Tract Mucosal Immunity and the Vaginal Microbiome.
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Impact of platinum-based chemotherapy on circulating nucleic acid levels, protease activities in blood and disseminated tumor cells in bone marrow of ovarian cancer patients.
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Impact of uPA/PAI-1 and disseminated cytokeratin-positive cells in breast cancer.
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Improved circulating half-life and efficacy of an antibody-interleukin 2 immunocytokine based on reduced intracellular proteolysis.
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Improved detection of ovarian cancer metastases by intraoperative quantitative fluorescence protease imaging in a pre-clinical model.
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Improving the efficacy of proteasome inhibitors in the treatment of renal cell carcinoma by combination with the human immunodeficiency virus (HIV)-protease inhibitors lopinavir or nelfinavir.
Neoplasms
In silico analysis reveals a shared immune signature in CASP8-mutated carcinomas with varying correlations to prognosis.
Neoplasms
In Situ Proapoptotic Peptide-Generating Rapeseed Protein-Based Nanocomplexes Synergize Chemotherapy for Cathepsin-B Overexpressing Breast Cancer.
Neoplasms
In Situ Protease Secretion Visualization and Metastatic Lymph Nodes Imaging via a Cell Membrane-Anchored Upconversion Nanoprobe.
Neoplasms
In vitro antitumor and anti-angiogenic activities of a shrimp chondroitin sulfate.
Neoplasms
In vitro degradation of extracellular matrix with Mr 52,000 cathepsin D secreted by breast cancer cells.
Neoplasms
In vitro inhibition of endothelial cell growth by the antiangiogenic drug AGM-1470 (TNP-470) and the anti-endoglin antibody TEC-11.
Neoplasms
In vitro inhibition of human MMP-2 collagenolytic and gelatinolytic activity by neutralizing monoclonal antibodies.
Neoplasms
In vitro inhibition of human sarcoma cells' invasive ability by bis(5-amidino-2-benzimidazolyl)methane--a novel esteroprotease inhibitor.
Neoplasms
In vitro stability of endogenous parathyroid hormone-related protein in blood and plasma.
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In vivo characterization of activatable cell penetrating peptides for targeting protease activity in cancer.
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In vivo covalent cross-linking of photon-converted rare-earth nanostructures for tumour localization and theranostics.
Neoplasms
In vivo imaging of membrane type-1 matrix metalloproteinase with a novel activatable near-infrared fluorescence probe.
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In vivo imaging of tissue-remodeling activity involving infiltration of macrophages by a systemically administered protease-activatable probe in colon cancer tissues.
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In vivo invasion of head and neck squamous cell carcinoma cells does not require macrophages.
Neoplasms
In-depth LC-MS/MS analysis of the chicken ovarian cancer proteome reveals conserved and novel differentially regulated proteins in humans.
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In-silico analysis of kallikrein gene expression in pancreatic and colon cancers.
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In-silico evidence of ADAM metalloproteinase pathology in cancer signaling networks.
Neoplasms
In-vivo imaging of tumor associated urokinase-type plasminogen activator activity.
Neoplasms
Increase in ceramide level alters the lysosomal targeting of cathepsin D prior to onset of apoptosis in HT-29 colon cancer cells.
Neoplasms
Increase in proteins involved in mitochondrial fission, mitophagy, proteolysis and antioxidant response in type I endometrial cancer as an adaptive response to respiratory complex I deficiency.
Neoplasms
Increase of anti-metastatic efficacy by selectivity- but not affinity-optimization of synthetic serine protease inhibitors.
Neoplasms
Increase of lipid plasma concentrations under protease inhibitor-containing regimens are not related to modifications of the tumour necrosis factor system.
Neoplasms
Increased content of chondroitin sulfate proteoglycan in human colorectal carcinoma metastases compared with the primary tumor as determined by an anti-chondroitin-sulfate monoclonal antibody.
Neoplasms
Increased expression of matriptase is associated with histopathologic grades of cervical neoplasia.
Neoplasms
Increased expression of ubiquitin-specific protease 22 can promote cancer progression and predict therapy failure in human colorectal cancer.
Neoplasms
Increased levels of cathepsin B and L, urokinase-type plasminogen activator and its inhibitor type-1 as an early event in gastric carcinogenesis.
Neoplasms
Increased von Willebrand factor over decreased ADAMTS-13 activity is associated with poor prognosis in patients with advanced non-small-cell lung cancer.
Neoplasms
Increasing C-Terminal Hydrophobicity Improves the Cell Permeability and Antiproliferative Activity of PACE4 Inhibitors against Prostate Cancer Cell Lines.
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Increasing expression of serine protease matriptase in ovarian tumors: tissue microarray analysis of immunostaining score with clinicopathological parameters.
Neoplasms
Indomethacin-guided cancer selective prodrug conjugate activated by histone deacetylase and tumour-associated protease.
Neoplasms
Induction of a novel Ca2+-dependent chymotrypsin-like serine protease by tumor promoters in rat livers.
Neoplasms
Induction of apoptosis in the LNCaP human prostate carcinoma cell line and prostate adenocarcinomas of SV40T antigen transgenic rats by the Bowman-Birk inhibitor.
Neoplasms
Induction of CD4(+) and CD8(+) T-cell responses to the human stromal antigen, fibroblast activation protein: implication for cancer immunotherapy.
Neoplasms
Induction of intracellular signalling in human endothelial cells by the hyaluronan-binding protease involves two distinct pathways.
Neoplasms
Influence of highly active anti-retroviral therapy on response to treatment and survival in patients with acquired immunodeficiency syndrome-related non-Hodgkin's lymphoma treated with cyclophosphamide, hydroxydoxorubicin, vincristine and prednisone.
Neoplasms
Influence of treatment with tamoxifen and change in tumor burden on the IGF-system in breast cancer patients.
Neoplasms
Inhibiting USP14 ameliorates inflammatory responses in trophoblast cells by suppressing MAPK/NF-?B signaling.
Neoplasms
Inhibition of 12-O-tetradecanoylphorbol-13-acetate induction of epidermal transglutaminase activity by protease inhibitors.
Neoplasms
Inhibition of a protease associated with tumour cells and the probable mechanism of regulation of this interaction in vivo.
Neoplasms
Inhibition of a tumour protease with 3,4-dichloroisocoumarin, pentamidine-isethionate and guanidino derivatives.
Neoplasms
Inhibition of benzopyrene-induced forestomach tumors by field bean protease inhibitor(s).
Neoplasms
Inhibition of cysteine cathepsin protease activity enhances chemotherapy regimens by decreasing tumor growth and invasiveness in a mouse model of multistage cancer.
Neoplasms
Inhibition of cytokine-driven human immunodeficiency virus type 1 replication by protease inhibitor.
Neoplasms
Inhibition of growth and induction of differentiation in a malignant human glioma cell line by normal leptomeningeal extracellular matrix proteins.
Neoplasms
Inhibition of growth of 3-methylcholanthrene-induced mouse skin tumor by protease inhibitor [N,N-dimethylcarbamoylmethyl 4-(4-guanidinobenzoyloxy)-phenylacetate] methanesulfate.
Neoplasms
Inhibition of guanidinobenzoatase: evidence for multiple forms of this protease on different tumour cells.
Neoplasms
Inhibition of Lon protease by triterpenoids alters mitochondria and is associated to cell death in human cancer cells.
Neoplasms
Inhibition of MALT1 decreases neuroinflammation and pathogenicity of virulent rabies virus in mice.
Neoplasms
Inhibition of MT1-MMP activity using functional antibody fragments selected against its hemopexin domain.
Neoplasms
Inhibition of plasminogen activator inhibitor-1: its mechanism and effectiveness on coagulation and fibrosis.
Neoplasms
Inhibition of prostate cancer neovascularization and growth by urokinase-plasminogen activator receptor blockade.
Neoplasms
Inhibition of proteolytic enzymes in the in vitro amnion model for basement membrane invasion.
Neoplasms
Inhibition of Serine Protease Activity Protects Against High Fat Diet-Induced Inflammation and Insulin Resistance.
Neoplasms
Inhibition of SUMO-specific protease 1 induces apoptosis of astroglioma cells by regulating NF-?B/Akt pathways.
Neoplasms
Inhibition of the interaction of urokinase-type plasminogen activator (uPA) with its receptor (uPAR) by synthetic peptides.
Neoplasms
Inhibition of the tumor-associated urokinase-type plasminogen activation system: effects of high-level synthesis of soluble urokinase receptor in ovarian and breast cancer cells in vitro and in vivo.
Neoplasms
Inhibition of tumour cell invasion by protease inhibitors: correlation with the protease profile.
Neoplasms
Inhibition of Ubiquitin-Specific Protease 14 Suppresses Cell Proliferation and Synergizes with Chemotherapeutic Agents in Neuroblastoma.
Neoplasms
Inhibition of USP1 induces apoptosis via ID1/AKT pathway in B-cell acute lymphoblastic leukemia cells.
Neoplasms
Inhibition of USP11 sensitizes gastric cancer to chemotherapy via suppressing RhoA and Ras-mediated signaling pathways.
Neoplasms
Inhibition properties of Sepharose-bound trypsin and a protease on the surface of Ehrlich ascites tumour cells.
Neoplasms
Inhibitor-GCPII Interaction: Selective and Robust System for Targeting Cancer Cells with Structurally Diverse Nanoparticles.
Neoplasms
Inhibitory effect of a serine protease inhibitor, FOY-305 on the invasion and metastasis of human pancreatic cancers.
Neoplasms
Inhibitory effect of lignin from Canna edulis Ker residues on trypsin: kinetics and molecular docking studies.
Neoplasms
Inhibitory effect of soluble EP2 receptor on ovarian tumor growth in nude mice and utility of TMPRSS4 as a combinatorial molecular target.
Neoplasms
Inhibitory effects of the recombinant human serine protease inhibitor Hespintor on the proliferation, migration and invasion of hepatocellular carcinoma cells.
Neoplasms
Inhibitory role of plasminogen activator inhibitor-1 in invasion and proliferation of HLE hepatocellular carcinoma cells.
Neoplasms
Insights into the broad cellular effects of nelfinavir and the HIV protease inhibitors supporting their role in cancer treatment and prevention.
Neoplasms
Insights into the Porcine Reproductive and Respiratory Syndrome Virus Viral Ovarian Tumor Domain Protease Specificity for Ubiquitin and Interferon Stimulated Gene Product 15.
Neoplasms
Insulin-induced epidermal growth factor activation in vascular smooth muscle cells is ADAM-dependent.
Neoplasms
Insulin-like growth factor binding protein (IGFBP) proteases: functional regulators of cell growth.
Neoplasms
Insulin-like growth factor binding protein-3 concentrations and insulin-like growth factor binding protein-3 protease activity in sera of patients with malignant solid tumors or leukemia.
Neoplasms
Insulin-like growth factor I, IGF binding protein 3, and IGFBP protease activity: relation to anthropometric indices in solid tumours or leukaemia.
Neoplasms
Integrated functions of membrane-type 1 matrix metalloproteinase in regulating cancer malignancy: Beyond a proteinase.
Neoplasms
Integrative p53, micro-RNA and Cathepsin Protease Co-Regulatory Expression Networks in Cancer.
Neoplasms
Interactions of the third component of human complement (C3) with tumour cells: evidence for presence of C3b acceptor sites and direct activation of C3 by tumour cells.
Neoplasms
Interferon-alpha2b With Protease Inhibitor-Based Antiretroviral Therapy in Patients With AIDS-Associated Kaposi Sarcoma: An AIDS Malignancy Consortium Phase I Trial.
Neoplasms
Interferons and progesterone for establishment and maintenance of pregnancy: interactions among novel cell signaling pathways.
Neoplasms
Interleukin-1 and tumor necrosis factor-alpha increase insulin-like growth factor-binding protein-3 (IGFBP-3) production and IGFBP-3 protease activity in human articular chondrocytes.
Neoplasms
Interleukin-27 expression modifies prostate cancer cell crosstalk with bone and immune cells in vitro.
Neoplasms
Interleukin-6 induces proteolysis by activating intracellular proteases (cathepsins B and L, proteasome) in C2C12 myotubes.
Neoplasms
Internalization by multiple endocytic pathways and lysosomal processing impact maspin-based therapeutics.
Neoplasms
Interplay of transcription factors STAT3, STAT1 and AP-1 mediates activity of the matrix metallo-proteinase-1 promoter in colorectal carcinoma cells.
Neoplasms
Intestinal secretory factor released by macrophages stimulated with Clostridium difficile toxin A: role of interleukin 1beta.
Neoplasms
Intra- and intersubunit changes accompanying thermal activation of the HtrA2(Omi) protease homotrimer.
Neoplasms
Intracellular delivery of peptide drugs using viral nanoparticles of bacteriophage P22: covalent loading and cleavable release.
Neoplasms
Intracellular localization of the tumor suppressor HtrA1/Prss11 and its association with HPV16 E6 and E7 proteins.
Neoplasms
Intracellular Serine Protease Inhibitor SERPINB4 Inhibits Granzyme M-Induced Cell Death.
Neoplasms
Intricate structural coordination and domain plasticity regulate activity of serine protease HtrA2.
Neoplasms
Involvement of a serine protease in the synthesis of platelet-activating factor by endothelial cells stimulated by tumor necrosis factor-alpha or interleukin-1 alpha.
Neoplasms
Involvement of a serine protease, but not of neutrophil elastase, in tumor necrosis factor-induced lethal hepatitis and induction of platelet-activating factor.
Neoplasms
Involvement of urokinase and its receptor in the invasiveness of human prostatic carcinoma cell lines.
Neoplasms
Ionizing radiation and TNF-alpha and stimulated expression of alpha1-antichymotrypsin gene in human squamous carcinoma cells.
Neoplasms
Is nelfinavir exposure associated with cancer incidence in HIV-positive individuals?
Neoplasms
Is plasminogen activator inhibitor-1 the molecular switch that governs urokinase receptor-mediated cell adhesion and release?
Neoplasms
Is There a Trojan Horse to Aggressive Pancreatic Cancer Biology? A Review of the Trypsin-PAR2 Axis to Proliferation, Early Invasion, and Metastasis.
Neoplasms
Isolation and characterization of a novel mung bean protease inhibitor with antipathogenic and anti-proliferative activities.
Neoplasms
Isolation and characterization of an inhibitory human monoclonal antibody specific to the urokinase-type plasminogen activator, uPA.
Neoplasms
Isolation of multiple types of plasminogen activator inhibitors from vascular smooth muscle cells.
Neoplasms
Isolation of undifferentiated female germline cells from adult Drosophila ovaries.
Neoplasms
Isolation of Undifferentiated Female Germline Cells from Adult Drosophila Ovaries.
Neoplasms
It is All About Proteases: From Drug Delivery to In Vivo Imaging and Photomedicine.
Neoplasms
ITIH5, a novel member of the inter-alpha-trypsin inhibitor heavy chain family is downregulated in breast cancer.
Neoplasms
Jak1-STAT3 Signals Are Essential Effectors of the USP6/TRE17 Oncogene in Tumorigenesis.
Neoplasms
Kallikrein-related peptidase 6 can cleave human-muscle-type 6-phosphofructo-1-kinase into highly active shorter fragments.
Neoplasms
Kaposi's sarcoma and non-Hodgkin's lymphoma incidence trends in AIDS Clinical Trial Group study participants.
Neoplasms
Knock-down of ubiquitin-specific protease 22 by micro-RNA interference inhibits colorectal cancer growth.
Neoplasms
Knock-down of USP22 by small interfering RNA interference inhibits HepG2 cell proliferation and induces cell cycle arrest.
Neoplasms
Knockdown of SERPINE1 reverses resistance of triple?negative breast cancer to paclitaxel via suppression of VEGFA.
Neoplasms
Knockdown of TMPRSS3 inhibits cell proliferation, migration/invasion and induces apoptosis of glioma cells.
Neoplasms
Knockdown of ubiquitin?specific protease 51 attenuates cisplatin resistance in lung cancer through ubiquitination of zinc?finger E?box binding homeobox 1.
Neoplasms
Knockdown of USP28 enhances the radiosensitivity of esophageal cancer cells via the c-Myc/hypoxia-inducible factor-1 alpha pathway.
Neoplasms
Kondrat'eva ligation: Diels-Alder-based irreversible reaction for bioconjugation.
Neoplasms
Kunitz type protease inhibitor from the canine tapeworm as a potential therapeutic for melanoma.
Neoplasms
Label-Free Quantitation and Mapping of the ErbB2 Tumor Receptor by Multiple Protease Digestion with Data-Dependent (MS1) and Data-Independent (MS2) Acquisitions.
Neoplasms
Labelling of tumour cells with a biotinylated inhibitor of a cell surface protease.
Neoplasms
Lack of apoptotic protease activating factor-1 expression and resistance to hypoxia-induced apoptosis in cervical cancer.
Neoplasms
LAIR-1 shedding from human fibroblast-like synoviocytes in rheumatoid arthritis following TNF-? stimulation.
Neoplasms
Learning from host-defense peptides: cationic, amphipathic peptoids with potent anticancer activity.
Neoplasms
Lentivirus-mediated knockdown of TSP50 suppresses the growth of non-small cell lung cancer cells via G0/G1 phase arrest.
Neoplasms
Levels of proteolytic activities as intermediate marker endpoints in oral carcinogenesis.
Neoplasms
Levels of uPA and PAI-1 in breast cancer and its correlation to Ki67-index and results of a 21-multigene-array.
Neoplasms
Lewis lung carcinoma cells enhance the synthesis of C3 and are opsonized by C3 secreted from murine macrophages.
Neoplasms
LGR5-Targeted Antibody-Drug Conjugate Eradicates Gastrointestinal Tumors and Prevents Recurrence.
Neoplasms
Library-based selection of retroviruses selectively spreading through matrix metalloprotease-positive cells.
Neoplasms
LIM kinase 1 increases tumor metastasis of human breast cancer cells via regulation of the urokinase-type plasminogen activator system.
Neoplasms
Limitation of nuclear division by protease inhibitors in cytochalasin-B-treated tumor cells.
Neoplasms
Lipodystrophy in patients with HIV-1 infection: effect of stopping protease inhibitors on TNF-alpha and TNF-receptor levels, and on metabolic parameters.
Neoplasms
Lipopolysaccharide-related stimuli induce expression of the secretory leukocyte protease inhibitor, a macrophage-derived lipopolysaccharide inhibitor.
Neoplasms
Liver cancer protease activity profiles support therapeutic options with matrix metalloproteinase-activatable oncolytic measles virus.
Neoplasms
Localization, expression and genomic structure of the gene encoding the human serine protease testisin.
Neoplasms
Lon Peptidase 2, Peroxisomal (LONP2) Contributes to Cervical Carcinogenesis via Oxidative Stress.
Neoplasms
Long-term feeding of field bean protein containing protease inhibitors suppresses virus-induced mammary tumors in mice.
Neoplasms
LONP1 and ClpP cooperatively regulate mitochondrial proteostasis for cancer cell survival.
Neoplasms
LonP1 Differently Modulates Mitochondrial Function and Bioenergetics of Primary Versus Metastatic Colon Cancer Cells.
Neoplasms
Lopinavir-ritonavir dramatically affects the pharmacokinetics of irinotecan in HIV patients with Kaposi's sarcoma.
Neoplasms
Loss of ADAM9 expression impairs ?1 integrin endocytosis, focal adhesion formation and cancer cell migration.
Neoplasms
Loss of ADAM9 Leads to Modifications of the Extracellular Matrix Modulating Tumor Growth.
Neoplasms
Loss of cathepsin L activity promotes claudin-1 overexpression and intestinal neoplasia.
Neoplasms
Loss of ectodomain shedding due to mutations in the metalloprotease and cysteine-rich/disintegrin domains of the tumor necrosis factor-alpha converting enzyme (TACE).
Neoplasms
Loss of maspin expression contributes to a more invasive potential in malignant melanoma.
Neoplasms
Loss of Maspin Expression in Bladder Cancer: Its Relationship with p53 and Clinicopathological Parameters.
Neoplasms
Loss of Maspin expression is a negative prognostic factor in common salivary gland tumors.
Neoplasms
Loss of maspin is a helpful prognosticator in colorectal cancer: a tissue microarray analysis.
Neoplasms
Loss of prostasin (PRSS8) in human bladder transitional cell carcinoma cell lines is associated with epithelial-mesenchymal transition (EMT).
Neoplasms
Low cathepsin D and low plasminogen activator type 1 inhibitor in tumor cytosols defines a group of node negative breast cancer patients with low risk of recurrence.
Neoplasms
Low density lipoprotein receptor related protein gene amplification and 766T polymorphism in astrocytomas.
Neoplasms
LPS-induced signals in activation of caspase-3-like protease, a key enzyme regulating apoptotic cell damage into a macrophage-like cell line, J774.1, in the presence of cycloheximide.
Neoplasms
Lysosomal serine protease CLN2 regulates tumor necrosis factor-alpha-mediated apoptosis in a bid-dependent manner.
Neoplasms
Macrophage Dependent Cleavage of the Laminin Receptor {alpha}6{beta}1 in Prostate Cancer.
Neoplasms
Macrophage Elastase Induces TRAIL-mediated Tumor Cell Death Through its Carboxyterminal Domain.
Neoplasms
Macrophages and cathepsin proteases blunt chemotherapeutic response in breast cancer.
Neoplasms
Magnetic nanoparticle decorated anodic alumina nanotubes for fluorescent detection of cathepsin B.
Neoplasms
Malignancy in perinatally human immunodeficiency virus-infected children in the United States.
Neoplasms
Malignant tumor disease as a sub-chronic, progressive intoxication on the basis of the perpetuation of the release of amino acids, initiated by a retrograde-differentiated muscle degradation protease.
Neoplasms
MALT1 is a critical mediator of PAR1-driven NF-?B activation and metastasis in multiple tumor types.
Neoplasms
Mammary serine protease inhibitor (Maspin) binds directly to interferon regulatory factor 6: identification of a novel serpin partnership.
Neoplasms
Mapping the topographic epitope landscape on the urokinase plasminogen activator receptor (uPAR) by surface plasmon resonance and X-ray crystallography.
Neoplasms
Marked Increased Production of Acute Phase Reactants by Skeletal Muscle during Cancer Cachexia.
Neoplasms
Maspin acts at the cell membrane to inhibit invasion and motility of mammary and prostatic cancer cells.
Neoplasms
Maspin and Mutant p53 expression in malignant melanoma and carcinoma: use of tissue microarray.
Neoplasms
Maspin enhances cisplatin chemosensitivity in bladder cancer T24 and 5637 cells and correlates with prognosis of muscle-invasive bladder cancer patients receiving cisplatin based neoadjuvant chemotherapy.
Neoplasms
Maspin expression and melanoma progression: a matter of sub-cellular localization.
Neoplasms
Maspin expression and subcellular localization in invasive ductal carcinoma of the breast: Prognostic significance and relation to microvessel density.
Neoplasms
Maspin expression in CIN 3, microinvasive squamous cell carcinoma, and invasive squamous cell carcinoma of the uterine cervix.
Neoplasms
Maspin expression inversely correlates with breast tumor progression in MMTV/TGF-alpha transgenic mouse model.
Neoplasms
Maspin expression was involved in colorectal adenoma-adenocarcinoma sequence and liver metastasis of tumors.
Neoplasms
Maspin expression, angiogenesis, prognostic parameters, and outcome in malignant melanoma.
Neoplasms
Maspin functions as tumor suppressor by increasing cell adhesion to extracellular matrix in prostate tumor cells.
Neoplasms
Maspin gene expression in tumor suppression induced by overexpressing manganese-containing superoxide dismutase cDNA in human breast cancer cells.
Neoplasms
Maspin gene expression is a significant prognostic factor in resected non-small cell lung cancer (NSCLC) Maspin in NSCLC.
Neoplasms
Maspin influences response to doxorubicin by changing the tumor microenvironment organization.
Neoplasms
Maspin inhibits macrophage phagocytosis and enhances inflammatory cytokine production via activation of NF-?B signaling.
Neoplasms
Maspin is a PTEN-Upregulated and p53-Upregulated Tumor Suppressor Gene and Acts as an HDAC1 Inhibitor in Human Bladder Cancer.
Neoplasms
Maspin is involved in bone matrix maturation by enhancing the accumulation of latent TGF-beta.
Neoplasms
Maspin mediates the gemcitabine sensitivity of hormone-independent prostate cancer.
Neoplasms
Maspin nuclear localization is linked to favorable morphological features in pulmonary adenocarcinoma.
Neoplasms
Maspin suppresses growth, proliferation and invasion in cutaneous squamous cell carcinoma cells.
Neoplasms
Maspin, a serpin with tumor-suppressing activity in human mammary epithelial cells.
Neoplasms
Maspin, p53, p63, and Ki-67 in epithelial lesions of the tongue: from hyperplasia through dysplasia to carcinoma.
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Maspin, VEGF and p53 Expression in Small Biopsies of Primary Advanced Lung Cancer and Relationship with Clinicopathologic Parameters.
Neoplasms
Mass spectrometric proteomics profiles of in vivo tumor secretomes: capillary ultrafiltration sampling of regressive tumor masses.
Neoplasms
Mast cell phenotype, TNF? expression and degranulation status in non-small cell lung cancer.
Neoplasms
Mast cell positivity to tryptase correlates with metastatic lymph nodes in gastrointestinal cancer patients treated surgically.
Neoplasms
Mast Cells Positive to Tryptase and c-Kit Receptor Expressing Cells Correlates with Angiogenesis in Gastric Cancer Patients Surgically Treated.
Neoplasms
Mathematical modeling of capillary formation and development in tumor angiogenesis: penetration into the stroma.
Neoplasms
Matriptase activates stromelysin (MMP-3) and promotes tumor growth and angiogenesis.
Neoplasms
Matriptase and HAI-1 are expressed by normal and malignant epithelial cells in vitro and in vivo.
Neoplasms
Matrix metalloproteinase 3 is present in the cell nucleus and is involved in apoptosis.
Neoplasms
Matrix metalloproteinase-2, squamous cell carcinoma antigen, and tissue polypeptide-specific antigen expression in Egyptian patients with cervical carcinoma: Relationship with prognosis.
Neoplasms
Matrix metalloproteinase-26 is associated with estrogen-dependent malignancies and targets alpha1-antitrypsin serpin.
Neoplasms
Matrix metalloproteinase-9 (MMP-9) as an activator of nanosystems for targeted drug delivery in pancreatic cancer.
Neoplasms
Matrix metalloproteinase-9 regulates tumor cell invasion through cleavage of protease nexin-1.
Neoplasms
May human epididymis 4 protein play a role in the etiopathogenesis of hemolysis, elevated liver enzymes and low platelets (HELLP) syndrome?
Neoplasms
MCF-7 mammary tumour cells express the myeloid cell differentiation controlling factor, serine protease 3/myeloblastin.
Neoplasms
Measurements of proteases or protease system components in blood to enhance prediction of disease risk or outcome in possible cancer.
Neoplasms
Mechanism of BCG-activated macrophage-induced tumor cell cytotoxicity: evidence for both oxygen-dependent and independent mechanisms.
Neoplasms
Mechanism of the inhibitory effect of protease inhibitor on tumor necrosis factor alpha production of monocytes.
Neoplasms
Mechanism of tumor and liver concentration of 67Ga: 67Ga binding substances in tumor tissues and liver.
Neoplasms
Mechanisms of site-specific dephosphorylation and kinase opposition imposed by PP2A regulatory subunits.
Neoplasms
Mechanisms of sterol regulatory element-binding protein-2 (SREBP-2) regulation of human prostasin gene expression.
Neoplasms
Mechanisms of target recognition and destruction in macrophage-mediated tumor cytotoxicity.
Neoplasms
Meeting the Challenge of Identifying New Treatments for Type 2-low Neutrophilic Asthma.
Neoplasms
Membrane type 1 matrix metalloproteinase detection in tumors, using the iodinated endogenous [123I]-tissue inhibitor 2 of metalloproteinases as imaging agent.
Neoplasms
Membrane type 1-matrix metalloproteinase cleaves off the NH2-terminal portion of heparin-binding epidermal growth factor and converts it into a heparin-independent growth factor.
Neoplasms
Membrane-Anchored Serine Proteases and Protease-Activated Receptor-2-Mediated Signaling: Co-Conspirators in Cancer Progression.
Neoplasms
Mesotrypsin promotes malignant growth of breast cancer cells through shedding of CD109.
Neoplasms
Metabolically Stabilized (68)Ga-NOTA-Bombesin for PET Imaging of Prostate Cancer and Influence of Protease Inhibitor Phosphoramidon.
Neoplasms
Metabolism and distribution of two highly potent and selective peptidomimetic inhibitors of matriptase.
Neoplasms
Metadegradomics: toward in vivo quantitative degradomics of proteolytic post-translational modifications of the cancer proteome.
Neoplasms
Metalloprotease-dependent protransforming growth factor-alpha ectodomain shedding in the absence of tumor necrosis factor-alpha-converting enzyme.
Neoplasms
Metalloproteinase disintegrins ADAM8 and ADAM19 are highly regulated in human primary brain tumors and their expression levels and activities are associated with invasiveness.
Neoplasms
Metastasis of transgenic breast cancer in plasminogen activator inhibitor-1 gene-deficient mice.
Neoplasms
Methods to analyze the effects of the urokinase system on cancer cell adhesion, proliferation, migration, and signal transduction events.
Neoplasms
Methylation of tumour suppressor genes APAF-1 and DAPK-1 and in vitro effects of demethylating agents in bladder and kidney cancer.
Neoplasms
Methylation-induced silencing of maspin contributes to the proliferation of human glioma cells.
Neoplasms
MHC class I antigen processing regulated by cytosolic proteolysis-short cuts that alter peptide generation.
Neoplasms
Micro-lymph node metastasis and its correlation with cathepsin D expression in early gastric cancer.
Neoplasms
Microencapsulated octreotide pamoate in advanced gastrointestinal and pancreatic cancer: a phase I study.
Neoplasms
Microglial Signaling in Chronic Pain with a Special Focus on Caspase 6, p38 MAP Kinase, and Sex Dependence.
Neoplasms
Microheterogeneous changes of the C1-esterase inhibitor in plasma cannot predict operability, postoperative complications, or recurrence in cancer surgery.
Neoplasms
microRNA-539 functions as a tumor suppressor in papillary thyroid carcinoma via the transforming growth factor ?1/Smads signaling pathway by targeting secretory leukocyte protease inhibitor.
Neoplasms
MiR-148b functions as a tumor suppressor by targeting endoplasmic reticulum metallo protease 1 in human endometrial cancer cells.
Neoplasms
miR-186 promotes tumor growth in cutaneous squamous cell carcinoma by inhibiting apoptotic protease activating factor-1.
Neoplasms
MiR-484 promotes non-small-cell lung cancer (NSCLC) progression through inhibiting Apaf-1 associated with the suppression of apoptosis.
Neoplasms
Mis-sorting of procathepsin D in metastogenic tumor cells is not due to impaired synthesis of the phosphomannosyl signal.
Neoplasms
Mitochondrial ATP-Dependent Proteases-Biological Function and Potential Anti-Cancer Targets.
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Mitochondrial Caseinolytic Protease P: A Possible Novel Prognostic Marker and Therapeutic Target in Cancer.
Neoplasms
Mitochondrial ClpP serine protease-biological function and emerging target for cancer therapy.
Neoplasms
Mitochondrial Lon protease at the crossroads of oxidative stress, ageing and cancer.
Neoplasms
Mitogen-activated protein kinase kinase 4 (MAP2K4) promotes human prostate cancer metastasis.
Neoplasms
Mitogen-activated protein kinase-dependent and -independent routes control shedding of transmembrane growth factors through multiple secretases.
Neoplasms
MMP-2 responsive polymeric micelles for cancer-targeted intracellular drug delivery.
Neoplasms
Modeling to capture bystander-killing effect by released payload in target positive tumor cells.
Neoplasms
Modified immunoradiometric assay of parathyroid hormone-related protein: clinical application in the differential diagnosis of hypercalcemia.
Neoplasms
Modular Pore-Forming Immunotoxins with Caged Cytotoxicity Tailored by Directed Evolution.
Neoplasms
Modulation of antigen processing and presentation by persistent virus infections and in tumors.
Neoplasms
Modulation of cystatin C expression impairs the invasive and tumorigenic potential of human glioblastoma cells.
Neoplasms
Modulation of lung tumor development in mice with the soybean-derived Bowman-Birk protease inhibitor.
Neoplasms
Modulation of the urokinase-type plasminogen activator receptor by the beta6 integrin subunit.
Neoplasms
Molecular and mechanistic validation of delayed healing rat wounds as a model for human chronic wounds.
Neoplasms
Molecular cloning and characterization of a novel esophageal cancer related gene.
Neoplasms
Molecular cloning of fibroblast activation protein alpha, a member of the serine protease family selectively expressed in stromal fibroblasts of epithelial cancers.
Neoplasms
Molecular Imaging of Cancer Using X-ray Computed Tomography with Protease Targeted Iodinated Activity-Based Probes.
Neoplasms
Molecular recognition of fibroblast activation protein for diagnostic and therapeutic applications.
Neoplasms
Molecular-dynamics-simulation-driven design of a protease-responsive probe for in-vivo tumor imaging.
Neoplasms
Monitoring of chemotherapy successfulness of platina/taxol chemotherapy protocol by using determination of serum urokinase plasminogen activator (uPA) and soluble urokinase plasminogen activator receptor (suPAR) in patients with ovarian carcinoma FIGO II and III stage.
Neoplasms
Monitoring protease activity in biological tissues using antibody prodrugs as sensing probes.
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Monitoring Proteolytic Activity in Real Time: A New World of Opportunities for Biosensors.
Neoplasms
Morphine Modulates Interleukin-4- or Breast Cancer Cell-induced Pro-metastatic Activation of Macrophages.
Neoplasms
Mosaic structure of the secreted ECM metalloproteases and interaction of the type IV collagenases with inhibitors.
Neoplasms
Most effective colon cancer chemopreventive agents in rats: a systematic review of aberrant crypt foci and tumor data, ranked by potency.
Neoplasms
Motor and memory testing of long-lived pregnancy-associated plasma protein--a knock-out mice.
Neoplasms
Mouse fibroblast activation protein: molecular cloning, alternative splicing and expression in the reactive stroma of epithelial cancers.
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Mouse fibroblast-activation protein--conserved Fap gene organization and biochemical function as a serine protease.
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mRNA expression and hypermethylation of tumor suppressor genes apoptosis protease activating factor-1 and death-associated protein kinase in oral squamous cell carcinoma.
Neoplasms
MT1-MMP activatable fluorogenic probes with enhanced specificity via high-affinity peptide conjugation for tumor imaging.
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MT1-MMP dependent repression of the tumor suppressor SPRY4 contributes to MT1-MMP driven melanoma cell motility.
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MT4-MMP and EGFR expression levels are key biomarkers for breast cancer patient response to chemotherapy and erlotinib.
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Multi-platform Affinity Proteomics Identify Proteins Linked to Metastasis and Immune Suppression in Ovarian Cancer Plasma.
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Multifunctional Albumin Nanoparticles As Combination Drug Carriers for Intra-Tumoral Chemotherapy.
Neoplasms
Multilevel regulation of IL-6R by IL-6-sIL-6R fusion protein according to the primitiveness of peripheral blood-derived CD133+ cells.
Neoplasms
Multimodal therapy for synergic inhibition of tumour cell invasion and tumour-induced angiogenesis.
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Multiparametric prognostic evaluation of biological factors in primary breast cancer.
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Multiple effects of alpha1-antitrypsin on breast carcinoma MDA-MB 468 cell growth and invasiveness.
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Multiple pathways of cell invasion are regulated by multiple families of serine proteases.
Neoplasms
Multiplex profiling of tumor associated proteolytic activity in serum of colorectal cancer patients.
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Multispectral Photoacoustic Imaging of Tumor Protease Activity with a Gold Nanocage-Based Activatable Probe.
Neoplasms
Murine mast cell lines as indicators of early events in mast cell and basophil development.
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Muscadine grape skin extract can antagonize Snail-cathepsin L-mediated invasion, migration and osteoclastogenesis in prostate and breast cancer cells.
Neoplasms
Mutant cytoskeletal and ECM peptides sensitive to the ST14 protease are associated with a worse outcome for glioblastoma multiforme.
Neoplasms
Mutant K-ras regulates cathepsin B localization on the surface of human colorectal carcinoma cells.
Neoplasms
Mutations at vicinity of catalytic sites of hepatitis C virus NS3 serine protease gene isolated from hepatocellular carcinoma tissue.
Neoplasms
N-glycan in the scavenger receptor cysteine-rich domain of hepsin promotes intracellular trafficking and cell surface expression.
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Na/H Exchangers and RhoA Regulate Acidic Extracellular pH-Induced Lysosome Trafficking in Prostate Cancer Cells.
Neoplasms
Nafamostat Mesilate Enhances the Radiosensitivity and Reduces the Radiation-Induced Invasive Ability of Colorectal Cancer Cells.
Neoplasms
Nafamostat mesilate, a nuclear factor kappa B inhibitor, enhances the antitumor action of radiotherapy on gallbladder cancer cells.
Neoplasms
Nafamostat mesilate, a serine protease inhibitor, suppresses interferon-gamma-induced up-regulation of programmed cell death ligand 1 in human cancer cells.
Neoplasms
Nano-scale proteomics approach using two-dimensional fibrin zymography combined with fluorescent SYPRO ruby dye.
Neoplasms
Natural proteolytic processing of hemofiltrate CC chemokine 1 generates a potent CC chemokine receptor (CCR)1 and CCR5 agonist with anti-HIV properties.
Neoplasms
Naturally produced outer membrane vesicles from Pseudomonas aeruginosa elicit a potent innate immune response via combined sensing of both lipopolysaccharide and protein components.
Neoplasms
Near infrared thoracoscopy of tumoral protease activity for improved detection of peripheral lung cancer.
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Near-Infrared Fluorescent Probes for the Detection of Cancer-Associated Proteases.
Neoplasms
Nectin-4, a new serological breast cancer marker, is a substrate for tumor necrosis factor-alpha-converting enzyme (TACE)/ADAM-17.
Neoplasms
Negative growth control of osteosarcoma cell by Bowman-Birk protease inhibitor from soybean; involvement of connexin 43.
Neoplasms
Negative regulation of urokinase receptor activity by a GPI-specific phospholipase C in breast cancer cells.
Neoplasms
Neither creatinine nor cystatin C-estimated glomerular filtration rate is optimal in oncology patients treated with targeted agents.
Neoplasms
Nelfinavir and other protease inhibitors in cancer: mechanisms involved in anticancer activity.
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Nelfinavir and Ritonavir Kill Bladder Cancer Cells Synergistically By Inducing Endoplasmic Reticulum Stress.
Neoplasms
Nelfinavir induces the unfolded protein response in ovarian cancer cells, resulting in ER vacuolization, cell cycle retardation and apoptosis.
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Neutrophil elastase as a diagnostic marker and therapeutic target in colorectal cancers.
Neoplasms
New relationships between prostatic intraepithelial neoplasia and prostatic carcinoma.
Neoplasms
NF-?B pathway took part in the development of apoptosis mediated by miR-15a and oxidative stress via mitochondrial pathway in ammonia-treated chicken splenic lymphocytes.
Neoplasms
NFE2L1 and NFE2L3 Complementarily Maintain Basal Proteasome Activity in Cancer Cells through CPEB3-Mediated Translational Repression.
Neoplasms
Nimbolide inhibits invasion and migration, and down-regulates uPAR chemokine gene expression, in two breast cancer cell lines.
Neoplasms
Nitric oxide increases the invasion of pancreatic cancer cells via activation of the PI3K-AKT and RhoA pathways after carbon ion irradiation.
Neoplasms
Nitric oxide regulates tumor cell cross-talk with stromal cells in the tumor microenvironment of the liver.
Neoplasms
NK cell protease granzyme M targets alpha-tubulin and disorganizes the microtubule network.
Neoplasms
NLRP7 deubiquitination by USP10 promotes tumor progression and tumor-associated macrophage polarization in colorectal cancer.
Neoplasms
No association between the 4g/5G polymorphism of the plasminogen activator inhibitor-1 gene promoter and autistic disorder.
Neoplasms
NO-mesalamine protects colonic epithelial cells against apoptotic damage induced by proinflammatory cytokines.
Neoplasms
Non-combinatorial library screening reveals subsite cooperativity and identifies new high efficiency substrates for kallikrein-related peptidase 14.
Neoplasms
Non-combinatorial library screening reveals subsite cooperativity and identifies new high-efficiency substrates for kallikrein-related peptidase 14.
Neoplasms
Non-invasive imaging of cysteine cathepsin activity in solid tumors using a 64Cu-labeled activity-based probe.
Neoplasms
Non-proteolytic, receptor/ligand interactions associate cellular membrane type-1 matrix metalloproteinase with the complement component C1q.
Neoplasms
Noncanonical Activation of Notch1 Protein by Membrane Type 1 Matrix Metalloproteinase (MT1-MMP) Controls Melanoma Cell Proliferation.
Neoplasms
Noninsecticidal parasporal proteins of a Bacillus thuringiensis serovar shandongiensis isolate exhibit a preferential cytotoxicity against human leukemic T cells.
Neoplasms
Nonpolarized secretion of human meprin alpha in colorectal cancer generates an increased proteolytic potential in the stroma.
Neoplasms
Novel challenges in exploring peptide ligands and corresponding tissue-specific endothelial receptors.
Neoplasms
Novel forms of squamous cell carcinoma antigen transcripts produced by alternative splicing.
Neoplasms
Novel molecular discovery of promising amidine-based thiazole analogues as potent dual Matrix Metalloproteinase-2 and 9 inhibitors: Anticancer activity data with prominent cell cycle arrest and DNA fragmentation analysis effects.
Neoplasms
Novel Protective Role for Ubiquitin-Specific Protease 18 in Pathological Cardiac Remodeling.
Neoplasms
Novel role of the human alveolar epithelium in regulating intra-alveolar coagulation.
Neoplasms
NRF3-POMP-20S proteasome assembly axis promotes cancer development via ubiquitin-independent proteolysis of p53 and Rb.
Neoplasms
NS3 protein of Hepatitis C virus associates with the tumour suppressor p53 and inhibits its function in an NS3 sequence-dependent manner.
Neoplasms
Nuclear cathepsin D enhances TRPS1 transcriptional repressor function to regulate cell cycle progression and transformation in human breast cancer cells.
Neoplasms
Nuclear localization of apoptosis protease activating factor-1 predicts survival after tumor resection in early-stage non-small cell lung cancer.
Neoplasms
Nuclear localization of mammary serine protease inhibitor (MASPIN): is its impact on the prognosis in laryngeal carcinoma due to a proapoptotic effect?
Neoplasms
Nuclear localization of maspin is essential for its inhibition of tumor growth and metastasis.
Neoplasms
Nuclear maspin expression correlates with the CpG island methylator phenotype and tumor aggressiveness in colorectal cancer.
Neoplasms
Nuclear Maspin expression is associated with response to adjuvant 5-fluorouracil based chemotherapy in patients with stage III colon cancer.
Neoplasms
Nuclear translocation of ADAM-10 contributes to the pathogenesis and progression of human prostate cancer.
Neoplasms
Obtusilactone A and (-)-sesamin induce apoptosis in human lung cancer cells by inhibiting mitochondrial Lon protease and activating DNA damage checkpoints.
Neoplasms
On-demand manipulation of tumorigenic microenvironments by nano-modulator for synergistic tumor therapy.
Neoplasms
ONC212 is a Novel Mitocan Acting Synergistically with Glycolysis Inhibition in Pancreatic Cancer.
Neoplasms
Oncogenic Ras Disrupts Epithelial Integrity by Activating the Transmembrane Serine Protease Hepsin.
Neoplasms
Oncogenicity evaluations of chemopreventive soy components in p53((+/-)) (p53 knockout) mice.
Neoplasms
One-step 18F-fluorination of smart positron emission tomography tracer for sensing furin activity in tumors.
Neoplasms
ONO 3403, a synthetic serine protease inhibitor, inhibits lipopolysaccharide-induced tumor necrosis factor-{alpha} and nitric oxide production and protects mice from lethal endotoxic shock.
Neoplasms
Operative ubiquitin-specific protease 22 deubiquitination confers a more invasive phenotype to cholangiocarcinoma.
Neoplasms
Optical imaging of spontaneous breast tumors using protease sensing 'smart' optical probes.
Neoplasms
Optical Imaging with a Cathepsin B Activated Probe for the Enhanced Detection of Esophageal Adenocarcinoma by Dual Channel Fluorescent Upper GI Endoscopy.
Neoplasms
Oral secretory leukocyte protease inhibitor (SLPI): Associations with oropharyngeal cancer and treatment outcome.
Neoplasms
Organization and chromosomal localization of the murine Testisin gene encoding a serine protease temporally expressed during spermatogenesis.
Neoplasms
Osteoblast-derived TGF-beta1 modulates matrix degrading protease expression and activity in prostate cancer cells.
Neoplasms
Osteonectin promotes prostate cancer cell migration and invasion: a possible mechanism for metastasis to bone.
Neoplasms
Osteopontin: it's role in regulation of cell motility and nuclear factor kappa B-mediated urokinase type plasminogen activator expression.
Neoplasms
OTUB1-mediated deubiquitination of FOXM1 up-regulates ECT-2 to promote tumor progression in renal cell carcinoma.
Neoplasms
OTUB2 Promotes Homologous Recombination Repair Through Stimulating Rad51 Expression in Endometrial Cancer.
Neoplasms
Ovarian tumor cells express a transmembrane serine protease: a potential candidate for early diagnosis and therapeutic intervention.
Neoplasms
Overexpression of a hybrid gene consisting of the amino-terminal fragment of urokinase and carboxyl-terminal domain of bikunin suppresses invasion and migration of human ovarian cancer cells in vitro.
Neoplasms
Overexpression of cathepsin B and urokinase plasminogen activator is associated with increased risk of recurrence and metastasis in patients with chondrosarcoma.
Neoplasms
Overexpression of squamous cell carcinoma antigen in idiopathic pulmonary fibrosis: clinicopathological correlations.
Neoplasms
Overexpression of testisin, a serine protease expressed by testicular germ cells, in epithelial ovarian tumor cells.
Neoplasms
Overexpression of the urokinase receptor mRNA splice variant uPAR-del4/5 affects tumor-associated processes of breast cancer cells in vitro and in vivo.
Neoplasms
Overexpression of TMPRSS4 in non-small cell lung cancer is associated with poor prognosis in patients with squamous histology.
Neoplasms
Overexpression of TMPRSS4 promotes tumor proliferation and aggressiveness in breast cancer.
Neoplasms
Overexpression of ubiquitin-specific protease 22 predicts poor survival in patients with early-stage non-small cell lung cancer.
Neoplasms
Overexpression of urinary plasminogen activator (uPA) protein and mRNA in thyroid carcinogenesis.
Neoplasms
Overexpression of USP5 contributes to tumorigenesis in non-small cell lung cancer via the stabilization of ?-catenin protein.
Neoplasms
Overview on human breast cancer with focus on prognostic and predictive factors with special attention on the tumour suppressor gene p53.
Neoplasms
Oxidative Stress-Induced Signaling Pathways Implicated in the Pathogenesis of Parkinson's Disease.
Neoplasms
p202, an interferon-inducible protein, mediates multiple antitumor activities in human pancreatic cancer xenograft models.
Neoplasms
P2Y2 nucleotide receptors mediate metalloprotease-dependent phosphorylation of epidermal growth factor receptor and ErbB3 in human salivary gland cells.
Neoplasms
PAIII prostate tumors express prostate specific antigen (PSA) in Lobund-Wistar rats.
Neoplasms
Pan-Cancer Analysis of Genomic and Prognostic Characteristics Associated With Coronavirus Disease 2019 Regulators.
Neoplasms
Pancreatic intraepithelial neoplasia is associated with chronic pancreatitis due to serine protease inhibitor kazal type 1 and cystic fibrosis transmembrane conductance regulator mutations.
Neoplasms
Pancreatic stellate cells potentiate proinvasive effects of SERPINE2 expression in pancreatic cancer xenograft tumors.
Neoplasms
PAR-1 mediated apoptosis of breast cancer cells by V. cholerae hemagglutinin protease.
Neoplasms
PAR1 signaling on tumor cells limits tumor growth by maintaining a mesenchymal phenotype in pancreatic cancer.
Neoplasms
Paracrine factor and cell-cell contact-mediated induction of protease and c-ets gene expression in malignant keratinocyte/dermal fibroblast cocultures.
Neoplasms
Paradoxical expression of maspin in gastric carcinomas: correlation with carcinogenesis and progression.
Neoplasms
Parity predisposes breasts to the oncogenic action of PAPP-A and activation of the collagen receptor DDR2.
Neoplasms
Pathophysiological functions of cathepsin D: Targeting its catalytic activity versus its protein binding activity?
Neoplasms
Patients with localized and disseminated tumors have reduced but measurable levels of ADAMTS-13 (von Willebrand factor cleaving protease).
Neoplasms
Patterns for normal colon mucosa and colon adenocarcinoma compared by two-dimensional gel electrophoresis.
Neoplasms
Peptide-Nanoparticle Hybrid SERS Probe for Dynamic Detection of Active Cancer Biomarker Enzymes.
Neoplasms
Peptides in cancer nanomedicine: Drug carriers, targeting ligands and protease substrates.
Neoplasms
Peptidomics-driven strategy reveals peptides and predicted proteases associated with oral cancer prognosis.
Neoplasms
Peptidomics-Driven Strategy Reveals Peptides and Predicted Proteases Associated With Oral Cancer Prognosis.
Neoplasms
Pericellular pH affects distribution and secretion of cathepsin B in malignant cells.
Neoplasms
pH-Responsive Pluronic F127-Lenvatinib-Encapsulated Halogenated Boron-Dipyrromethene Nanoparticles for Combined Photodynamic Therapy and Chemotherapy of Liver Cancer.
Neoplasms
Pharmacokinetics of PK1 and doxorubicin in experimental colon tumor models with differing responses to PK1.
Neoplasms
Pharmacological Inhibition of MALT1 Protease Leads to a Progressive IPEX-Like Pathology.
Neoplasms
Phase II Trial of Single Agent Val-boroPro (Talabostat) Inhibiting Fibroblast Activation Protein in Patients with Metastatic Colorectal Cancer.
Neoplasms
pHLIP(Var7)-P1AP suppresses tumor cell proliferation in MDA-MB-231 triple-negative breast cancer by targeting protease activated receptor 1.
Neoplasms
Phloretin suppresses metastasis by targeting protease and inhibits cancer stemness and angiogenesis in human cervical cancer cells.
Neoplasms
Phorbol 12-myristate 13-acetate-induced ectodomain shedding and phosphorylation of the human meprinbeta metalloprotease.
Neoplasms
Phorbol ester-induced morphological changes in transformed chick fibroblasts: evidence for direct catalytic involvement of plasminogen activator.
Neoplasms
Phosphonic pseudopeptides as human neutrophil elastase inhibitors--a combinatorial approach.
Neoplasms
Phosphorylation of the beta subunit of Na+K+-ATPase in Ehrlich ascites tumor by a membrane-bound protein kinase.
Neoplasms
Photoactivated Spatiotemporally-Responsive Nanosensors of in Vivo Protease Activity.
Neoplasms
Photodynamic molecular beacon triggered by fibroblast activation protein on cancer-associated fibroblasts for diagnosis and treatment of epithelial cancers.
Neoplasms
Pilot study evaluating the interaction between paclitaxel and protease inhibitors in patients with human immunodeficiency virus-associated Kaposi's sarcoma: an Eastern Cooperative Oncology Group (ECOG) and AIDS Malignancy Consortium (AMC) trial.
Neoplasms
Piperidine carbamate peptidomimetic inhibitors of the serine proteases HGFA, matriptase and hepsin.
Neoplasms
Placental-like alkaline phosphatase reactivity in human tumors: an immunohistochemical study of 520 cases.
Neoplasms
Plant seed protease inhibitors differentially affect innate immunity in a tumor microenvironment to control hepatocarcinoma.
Neoplasms
Plasma islet amyloid polypeptide is not an effective tumor marker for pancreatic cancer even when protease inhibitors and rapid freezing of specimens are utilized.
Neoplasms
Plasmin-activated prodrugs for cancer chemotherapy. 1. Synthesis and biological activity of peptidylacivicin and peptidylphenylenediamine mustard.
Neoplasms
Plasminogen activator activities in short-term tissue cultures of benign prostatic hyperplasia and prostatic carcinoma.
Neoplasms
Plasminogen activator activity in clonogenic cell populations separated from a murine fibrosarcoma.
Neoplasms
Plasminogen activator inhibitor (PAI) trap3, an exocellular peptide inhibitor of PAI-1, attenuates the rearrangement of F-actin and migration of cancer cells.
Neoplasms
Plasminogen activator inhibitor-1 (PAI-1) gene transfection inhibits the liver metastasis of pancreatic cancer by preventing angiogenesis.
Neoplasms
Plasminogen activator, fibronectin, lymphotoxin sensitivity, and natural skin reactivity relationships to guinea pig cell tumorigenicity.
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Plasminogen activators and inhibitors in the neuromuscular system: III. The serpin protease nexin I is synthesized by muscle and localized at neuromuscular synapses.
Neoplasms
PLAU Promotes Cell Proliferation and Epithelial-Mesenchymal Transition in Head and Neck Squamous Cell Carcinoma.
Neoplasms
Pleiotrophic inhibition of pericellular urokinase-type plasminogen activator system by endogenous tumor suppressive maspin.
Neoplasms
PO-36 - Thrombin Inhibition Preoperatively (TIP) in early breast cancer, the first clinical trial of NOACs as an anti-cancer agent: trial methodology.
Neoplasms
Positional-scanning fluorigenic substrate libraries reveal unexpected specificity determinants of DUBs (deubiquitinating enzymes).
Neoplasms
Potent and specific inhibition of the biological activity of the type-II transmembrane serine protease matriptase by the cyclic microprotein MCoTI-II.
Neoplasms
Potent blockade of hepatocyte growth factor-stimulated cell motility, matrix invasion and branching morphogenesis by antagonists of Grb2 Src homology 2 domain interactions.
Neoplasms
Potential importance of protease activated receptor (PAR)-1 expression in the tumor stroma of non-small-cell lung cancer.
Neoplasms
Potential MMP2-mediated availability of HLA binding, mutant ECM peptides reflects better melanoma survival rates and greater T-cell infiltrates.
Neoplasms
Potential molecular targets of tea polyphenols in human tumor cells: significance in cancer prevention.
Neoplasms
Potential role for cathepsin D in p53-dependent tumor suppression and chemosensitivity.
Neoplasms
Potential role of insulin-like growth factor binding protein-4 in the uncoupling of bone turnover in multiple myeloma.
Neoplasms
PPP6R3-USP6 amplification: Novel oncogenic mechanism in malignant nodular fasciitis.
Neoplasms
Pre-operative plasma levels of C-reactive protein, albumin and various plasma protease inhibitors for the pre-operative assessment of operability and recurrence in cancer surgery.
Neoplasms
Preclinical evaluation of Amblyomin-X, a Kunitz-type protease inhibitor with antitumor activity.
Neoplasms
Preliminary characterization of a Kazal-type serine protease inhibitor from Caiman crocodilus yacare plasma.
Neoplasms
Presence of chelonid fibropapilloma-associated herpesvirus in tumored and non-tumored green turtles, as detected by polymerase chain reaction, in endemic and non-endemic aggregations, Puerto Rico.
Neoplasms
Presence of insulin-like growth factor binding proteins correlates with tumor-promoting effects of matrix metalloproteinase 9 in breast cancer.
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Pretreatment with protease is a useful experimental strategy for enhancing adenovirus-mediated cancer gene therapy.
Neoplasms
Prevention of prostate-cancer metastasis in vivo by a novel synthetic inhibitor of urokinase-type plasminogen activator (uPA).
Neoplasms
Pro-tumor necrosis factor-alpha processing activity is tightly controlled by a component that does not affect notch processing.
Neoplasms
Probing the impact of nairovirus genomic diversity on viral ovarian tumor domain protease (vOTU) structure and deubiquitinase activity.
Neoplasms
Probing the interaction mechanism of small molecule inhibitors with matriptase based on molecular dynamics simulation and free energy calculations.
Neoplasms
Probody Therapeutics: An Emerging Class of Therapies Designed to Enhance On-Target Effects with Reduced Off-Tumor Toxicity for Use in Immuno-Oncology.
Neoplasms
Procedures for the quantitative protein determination of urokinase and its inhibitor, PAI-1, in human breast cancer tissue extracts by ELISA.
Neoplasms
Production of active MMP7 in E. coli and its application for metalloproteinase inhibitors screening.
Neoplasms
Production of lipolytic and proteolytic factors by a murine tumor-producing cachexia in the host.
Neoplasms
Proenzyme to urokinase-type plasminogen activator in human colon cancer: in vitro inhibition by monocyte minactivin after proteolytic activation.
Neoplasms
Profiling of proteolytic activities secreted by cancer cells using phage display substrate technology.
Neoplasms
Profiling treatment-specific post-translational modifications in a complex proteome with subtractive substrate phage display.
Neoplasms
Progelatinase A mRNA expression in cell lines derived from tumors in patients with metastatic renal cell carcinoma correlates inversely with survival.
Neoplasms
Progesterone receptor structure and protease activity in primary human endometrial carcinoma.
Neoplasms
Prognostic and clinicopathological significance of ubiquitin-specific protease 22 overexpression in cancers: evidence from a meta-analysis.
Neoplasms
Prognostic impact of urokinase-type plasminogen activator (PA), PA inhibitor type-1, and tissue-type PA antigen levels in node-negative breast cancer: a prospective study on multicenter basis.
Neoplasms
Prognostic relevance of uPAR-del4/5 and TIMP-3 mRNA expression levels in breast cancer.
Neoplasms
Prognostic role of maspin expression in patients with cervical dysplasia and cervical cancer.
Neoplasms
Prognostic significance of plasma matrix metalloprotease-2 in pancreatic cancer patients.
Neoplasms
Prognostic significance of SERPINE2 in gastric cancer and its biological function in SGC7901 cells.
Neoplasms
Prognostic significance of stromelysin 3, gelatinase A, and urokinase expression in breast cancer.
Neoplasms
Prognostic significance of the estrogen-regulated protein, cathepsin D, in breast cancer. An immunohistochemical study.
Neoplasms
Prognostic significance of the tumor suppressor gene maspin in non-small cell lung cancer.
Neoplasms
Prognostic significance of urokinase (uPA) and its inhibitor PAI-1 for survival in advanced ovarian carcinoma stage FIGO IIIc.
Neoplasms
Prognostic significance of USP10 as a tumor-associated marker in gastric carcinoma.
Neoplasms
Prognostic Value of ADAMTS Proteases and Their Substrates in Epithelial Ovarian Cancer.
Neoplasms
Prognostic value of kallikrein-related peptidase 6 protein expression levels in advanced ovarian cancer evaluated by automated quantitative analysis (AQUA).
Neoplasms
Prognostic Value of Matrix Metalloproteinase-1/ Proteinase-Activated Receptor-1 Signaling Axis in Hepatocellular Carcinoma.
Neoplasms
Programmed cell life: anti-apoptotic signaling and therapeutic strategies for neurodegenerative disorders.
Neoplasms
Proinflammatory cytokine production by cultured neonatal rat microglia after exposure to blood products.
Neoplasms
Proliferation of NS0 cells in protein-free medium: the role of cell-derived proteins, known growth factors and cellular receptors.
Neoplasms
Promotion of tumor growth by murine fibroblast activation protein, a serine protease, in an animal model.
Neoplasms
Propolis prevents inhibition of apoptosis by potassium bromate in CCD 841 human colon cell.
Neoplasms
Prostasin attenuates inducible nitric oxide synthase expression in lipopolysaccharide-induced urinary bladder inflammation.
Neoplasms
Prostasin serine protease inhibits breast cancer invasiveness and is transcriptionally regulated by promoter DNA methylation.
Neoplasms
Prostate Cancer-Associated Kallikrein-Related Peptidase 4 Activates Matrix Metalloproteinase-1 and Thrombospondin-1.
Neoplasms
Prostate specific antigen-alpha 2-macroglobulin complexes in prostate cancer patient sera.
Neoplasms
Prostate-specific antigen (PSA/hK3): a further player in the field of breast cancer diagnostics?
Neoplasms
Prostate-specific antigen in breast cyst fluid: possible role of prostate-specific antigen in hormone-dependent breast cancer.
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Prostate-specific antigen may serve as a pathological predictor in breast cancer.
Neoplasms
Prostate-specific antigen rising in Iranian men in correlation with body mass index, fasting blood sugar and blood lipid profile.
Neoplasms
Prostate-specific antigen, a serine protease, facilitates human prostate cancer cell invasion.
Neoplasms
Protease activated receptor 1 gene -506 I?/?D polymorphism in cancer patients with and without venous thrombosis.
Neoplasms
Protease activated receptor-1 inhibits the Maspin tumor-suppressor gene to determine the melanoma metastatic phenotype.
Neoplasms
Protease activated receptor-1, PAR1, promotes placenta trophoblast invasion and beta-catenin stabilization.
Neoplasms
Protease activated receptors (PAR)-1 and -2 mediate cellular effects of factor VII activating protease (FSAP).
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Protease Activated Receptors 1 and 2 Correlate Differently with Breast Cancer Aggressiveness Depending on Tumor ER Status.
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Protease Activity and Cell-Free DNA in Blood Plasma of Healthy Donors and Breast Cancer Patients.
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Protease activity at invadopodial focal digestive areas is dependent on NHE1-driven acidic pHe.
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Protease activity of urokinase and tumor progression in a syngeneic mammary cancer model.
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Protease Degradation of Protein Coronas and Its Impact on Cancer Cells and Drug Payload Release.
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Protease domain glycans affect oligomerization, disulfide bond formation, and stability of the meprin A metalloprotease homo-oligomer.
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Protease expression in giant cell tumour of bone: a comparative study on feline and human samples.
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Protease inhibitor 10 inhibits tumor necrosis factor alpha -induced cell death. Evidence for the formation of intracellular high M(r) protease inhibitor 10-containing complexes.
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Protease inhibitor antipain suppresses 12-O-tetradecanoyl-phorbol-13-acetate induction of plasminogen activator in transformable mouse embryo fibroblasts.
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Protease inhibitor-induced apoptosis: accumulation of wt p53, p21WAF1/CIP1, and induction of apoptosis are independent markers of proteasome inhibition.
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Protease inhibitors block the macrophage-mediated inhibition of tumor cell mitochondrial respiration.
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Protease inhibitors differentially regulate tumor necrosis factor-induced apoptosis, nuclear factor-kappa B activation, cytotoxicity, and differentiation.
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Protease inhibitors from processed legumes effectively inhibit superoxide generation in response to TPA.
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Protease inhibitors interfere with the transforming growth factor-beta-dependent but not the transforming growth factor-beta-independent pathway of tumor cell-mediated immunosuppression.
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Protease Inhibitors of Parasitic Flukes: Emerging Roles in Parasite Survival and Immune Defence.
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Protease inhibitors suppress fibrinolytic activity of herpesvirus-transformed cells.
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Protease inhibitors: possible preventive agents of various types of cancer and their mechanisms of action.
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Protease levels in breast, ovary, and other gynecological tumor tissues: prognostic importance in breast cancer.
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Protease nexin 1 induces apoptosis of prostate tumor cells through inhibition of X-chromosome-linked inhibitor of apoptosis protein.
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Protease nexin I expression is up-regulated in human skeletal muscle by injury-related factors.
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Protease Nexin I is a feedback regulator of EGF/PKC/MAPK/EGR1 signaling in breast cancer cells metastasis and stemness.
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Protease pretreatment increases the efficacy of adenovirus-mediated gene therapy for the treatment of an experimental glioblastoma model.
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Protease Serine S1 Family Member 8 (PRSS8) Inhibits Tumor Growth In Vitro and In Vivo in Human Non-Small Cell Lung Cancer.
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Protease-activated receptor (PAR) 2, but not PAR1, signaling promotes the development of mammary adenocarcinoma in polyoma middle T mice.
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Protease-activated receptor 2 signaling upregulates angiogenic growth factors in renal cell carcinoma.
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Protease-activated receptor-1 (hPar1), a survival factor eliciting tumor progression.
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Protease-activated receptor-1 drives pancreatic cancer progression and chemoresistance.
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Protease-activated receptor-1 impedes prostate and intestinal tumor progression in mice.
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Protease-activated receptor-2 accelerates intestinal tumor formation through activation of nuclear factor-?B signaling and tumor angiogenesis in ApcMin/+ mice.
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Protease-activated receptor-2 mediates the expression of inflammatory cytokines, antimicrobial peptides, and matrix metalloproteinases in keratinocytes in response to Propionibacterium acnes.
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Protease-activated receptors (PAR1 and PAR2) contribute to tumor cell motility and metastasis.
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Protease-triggered bioresponsive drug delivery for the targeted theranostics of malignancy.
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Proteases and cancer invasion: from belief to certainty. AACR meeting on proteases and protease inhibitors in cancer, Nyborg, Denmark, 14-18 June 1998.
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Proteases and cytokines as mediators of interactions between cancer and stromal cells in tumours.
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Proteases and their inhibitors as prognostic factors for high-grade serous ovarian cancer.
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Proteases as anti-cancer targets--molecular and biological basis for development of inhibitor-like drugs against cancer.
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Proteases associated with invadopodia, and their role in degradation of extracellular matrix.
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Proteasome Dependent Actin Remodeling Facilitates Antigen Extraction at the Immune Synapse of B Cells.
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Proteasome dysfunction triggers activation of SKN-1A/Nrf1 by the aspartic protease DDI-1.
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Protection against dimethylhydrazine-induced adenomatous tumors of the mouse colon by the dietary addition of an extract of soybeans containing the Bowman-Birk protease inhibitor.
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Protective effects of alanyl-glutamine supplementation against nelfinavir-induced epithelial impairment in IEC-6 cells and in mouse intestinal mucosa.
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Protective role of kallistatin in renal fibrosis via modulation of Wnt/?-catenin signaling.
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Protein arginine methylation of SERBP1 by protein arginine methyltransferase 1 affects cytoplasmic/nuclear distribution.
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Protein C inhibitor inhibits breast cancer cell growth, metastasis and angiogenesis independently of its protease inhibitory activity.
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Protein Delivery System Containing a Nickel-Immobilized Polymer for Multimerization of Affinity-Purified His-Tagged Proteins Enhances Cytosolic Transfer.
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Protein expression of matriptase and its cognate inhibitor HAI-1 in human prostate cancer: a tissue microarray and automated quantitative analysis.
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Proteolysis of Complement Factors iC3b and C5 by the Serine Protease Prostate-Specific Antigen in Prostatic Fluid and Seminal Plasma.
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Proteolysis-Responsive Rolling Circle Transcription Assay Enabling Femtomolar Sensitivity Detection of a Target Protease Biomarker.
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Proteolytic activities of mouse sarcoma 180 cells that are inhibited by Bowman-Birk and Kunitz protease inhibitors.
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Proteolytic activity during the growth of C6 astrocytoma in the murine spheroid implantation model.
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Proteolytic single hinge cleavage of pertuzumab impairs its Fc effector function and antitumor activity in vitro and in vivo.
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Proteomic analysis of cancer tissues: shedding light on carcinogenesis and possible biomarkers.
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Proteomic comparison of colorectal tumours and non-neoplastic mucosa from paired patient samples using iTRAQ mass spectrometry.
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Proteomic identification of serum biomarkers for head and neck cancer surveillance.
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Protumor activities of the immune response: insights in the mechanisms of immunological shift, oncotraining, and oncopromotion.
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Protumoral TSP50 Regulates Macrophage Activities and Polarization via Production of TNF-? and IL-1?, and Activation of the NF-?B Signaling Pathway.
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Protumorigenic Activity of Plasminogen Activator Inhibitor-1 Through an Antiapoptotic Function.
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PRSS8 is Downregulated and Suppresses Tumour Growth and Metastases in Hepatocellular Carcinoma.
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PSA-alpha-2-macroglobulin complex is enzymatically active in the serum of patients with advanced prostate cancer and can degrade circulating peptide hormones.
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Pseudo-active sites of protease domains: HGF/Met and Sonic hedgehog signaling in cancer.
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Pulmonary hypoplasia in mice lacking tumor necrosis factor-alpha converting enzyme indicates an indispensable role for cell surface protein shedding during embryonic lung branching morphogenesis.
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Purification and characterization of a complex containing matriptase and a Kunitz-type serine protease inhibitor from human milk.
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Purification and characterization of the mouse mammary tumor virus protease expressed in Escherichia coli.
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Purification and structural characterization of intact and fragmented nidogen obtained from a tumor basement membrane.
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Purification of a 24-kD protease from apoptotic tumor cells that activates DNA fragmentation.
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Purification of a factor from the granules of a rat natural killer cell line (RNK) that reduces tumor cell growth and changes tumor morphology. Molecular identity with a granule serine protease (RNKP-1).
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Quantitation of fibroblast activation protein (FAP)-specific protease activity in mouse, baboon and human fluids and organs.
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Quantitative electrochemical detection of cathepsin B activity in breast cancer cell lysates using carbon nanofiber nanoelectrode arrays toward identification of cancer formation.
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Quantitative electrochemical detection of cathepsin B activity in complex tissue lysates using enhanced AC voltammetry at carbon nanofiber nanoelectrode arrays.
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Quantitative proteomic analysis of proteins released by neoplastic prostate epithelium.
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Quantum dots based molecular beacons for in vitro and in vivo detection of MMP-2 on tumor.
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Quercetin inhibits invasion, migration and signalling molecules involved in cell survival and proliferation of prostate cancer cell line (PC-3).
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Quercetin suppresses the chymotrypsin-like activity of proteasome via inhibition of MEK1/ERK1/2 signaling pathway in hepatocellular carcinoma HepG2 cells.
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Racial Variation in the Utility of Urinary Biomarkers PCA3 and T2ERG in a Large Multicenter Study.
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Radiation-induced lung metastasis development is MT1-MMP-dependent in a triple-negative breast cancer mouse model.
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Radioimmunotherapy of fibroblast activation protein positive tumors by rapidly internalizing antibodies.
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RalA requirement for v-Src- and v-Ras-induced tumorigenicity and overproduction of urokinase-type plasminogen activator: involvement of metalloproteases.
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Rapid killing of actinomycin D-treated tumor cells by human monocytes. II. Cytotoxicity is independent of secretion of reactive oxygen intermediates and is suppressed by protease inhibitors.
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Rapid vessel regression, protease inhibition, and stromal normalization upon short-term vascular endothelial growth factor receptor 2 inhibition in skin carcinoma heterotransplants.
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Rational Engineering a Multichannel Upconversion Sensor for Multiplex Detection of Matrix Metalloproteinase Activities.
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Rationale for clinical trials of coagulation: reactive drugs in hepatocellular carcinoma.
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Re-activation of a dormant tumor suppressor gene maspin by designed transcription factors.
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Reactivation of MASPIN in non-small cell lung carcinoma (NSCLC) cells by artificial transcription factors (ATFs).
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Real-time in vivo molecular detection of primary tumors and metastases with ratiometric activatable cell-penetrating peptides.
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Recent advances in the development of legumain-selective chemical probes and peptide prodrugs.
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Recent advances in the understanding of brown spider venoms: From the biology of spiders to the molecular mechanisms of toxins.
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RECK forms cowbell-shaped dimers and inhibits matrix metalloproteinase-catalyzed cleavage of fibronectin.
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Recombinant Pierisin-5 Induces Apoptosis and Differential Expression of Bcl-2, Bax, and p53 in Human Cancer Cells.
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Recombinant tumor necrosis factor receptor p75 fusion protein (TNFR:Fc) alters endotoxin-induced activation of the kinin, fibrinolytic, and coagulation systems in normal humans.
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Recovery of cell subpopulations from human tumour xenografts following dissociation with different enzymes.
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Redirecting extracellular proteases to molecularly guide radiosensitizing drugs to tumors.
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Reduced gene expression of bikunin as a prognostic marker for renal cell carcinoma.
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Reduced Proteolytic Shedding of Receptor Tyrosine Kinases Is a Post-Translational Mechanism of Kinase Inhibitor Resistance.
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Reduced ubiquitin-specific protease 9X expression induced by RNA interference inhibits the bioactivity of hepatocellular carcinoma cells.
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Reduction of breast carcinoma tumor growth and lung colonization by overexpression of the soluble urokinase-type plasminogen activator receptor (CD87).
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Reduction of Membrane Protein CRIM1 Decreases E-Cadherin and Increases Claudin-1 and MMPs, Enhancing the Migration and Invasion of Renal Carcinoma Cells.
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Reference intervals and biological variation for kallikrein 6: influence of age and renal failure.
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Regulating the tumor suppressor gene maspin in breast cancer cells: a potential mechanism for the anticancer properties of tamoxifen.
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Regulation of catabolic gene expression in normal and degenerate human intervertebral disc cells: implications for the pathogenesis of intervertebral disc degeneration.
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Regulation of DNA methylation in human breast cancer. Effect on the urokinase-type plasminogen activator gene production and tumor invasion.
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Regulation of Fibroblast Activation Protein by Transforming Growth Factor Beta-1 in Glioblastoma Microenvironment.
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Regulation of inhibition of a protease on the surface of human colonic tumour cells.
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Regulation of matrix metalloproteinases - their role in tumor invasion and metastasis.
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Regulation of membrane-type 4 matrix metalloproteinase by SLUG contributes to hypoxia-mediated metastasis.
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Regulation of tumor necrosis factor-alpha and tumor necrosis factor converting enzyme in human osteoarthritis.
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Regulation of urokinase production by androgens in human prostate cancer cells: effect on tumor growth and metastases in vivo.
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Regulatory Mechanism of Collagen Degradation by Keratocytes and Corneal Inflammation: The Role of Urokinase-Type Plasminogen Activator.
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Regulatory processes affecting androgen receptor expression, stability, and function: potential targets to treat hormone-refractory prostate cancer.
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Relationship between protease activity and neu oncogene expression in patients with oral leukoplakia treated with the Bowman Birk Inhibitor.
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Relationship between urokinase-type plasminogen receptor, interleukin-8 gene expression and clinicopathological features in gastric cancer.
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Remote ischemic preconditioning does not influence lectin pathway protein levels in head and neck cancer patients undergoing surgery.
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Reprogramming epigenetic silencing: artificial transcription factors synergize with chromatin remodeling drugs to reactivate the tumor suppressor mammary serine protease inhibitor.
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Requirement for binding of catalytically active factor VIIa in tissue factor-dependent experimental metastasis.
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Retinoic acid inhibition of a tumour protease immobilised on cell surfaces and in free solution.
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Revealing favorable and unfavorable residues in cooperative positions in protease cleavage sites.
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Reverse biochemistry: use of macromolecular protease inhibitors to dissect complex biological processes and identify a membrane-type serine protease in epithelial cancer and normal tissue.
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Reversion of tumor phenotype in surface transplants of skin SCC cells by scaffold-induced stroma modulation.
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Review on marine sponge alkaloid, aaptamine: A potential antibacterial and anticancer drug.
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RGD and polyhistidine tumor homing peptides potentiates the action of human Maspin as an antineoplastic candidate.
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RHAMM, p21 combined phenotype identifies microsatellite instability-high colorectal cancers with a highly adverse prognosis.
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Rhbdf2 mutations increase its protein stability and drive EGFR hyperactivation through enhanced secretion of amphiregulin.
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Ritonavir blocks AKT signaling, activates apoptosis and inhibits migration and invasion in ovarian cancer cells.
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Ritonavir-Mediated Induction of Apoptosis in Pancreatic Cancer Occurs via the RB/E2F-1 and AKT Pathways.
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RNA interference-mediated USP22 gene silencing promotes human brain glioma apoptosis and induces cell cycle arrest.
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RNA splicing factor USP39 promotes glioma progression by inducing TAZ mRNA maturation.
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RNAi-mediated downregulation of urokinase plasminogen activator receptor and matrix metalloprotease-9 in human breast cancer cells results in decreased tumor invasion, angiogenesis and growth.
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RNK granule extract cytolysis: increased tumor susceptibility and release of proteochondroitin sulphate inhibitor in high NaCl.
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Role of caspase-3 and nitric oxide synthase-2 in gastric mucosal injury induced by indomethacin: effect of sucralfate.
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Role of cytoplasmic localization of maspin in promoting cell invasion in breast cancer with aggressive phenotype.
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Role of epidermal growth factor in the expression of A431 cancer cell protease and red blood cell cytotoxicity.
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Role of mammary serine protease inhibitor on the inflammatory response in oral lichen planus.
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Role of mesenchymal stem cell-derived fibrinolytic factor in tissue regeneration and cancer progression.
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Role of MMP9 on invadopodia formation in cells from adenoid cystic carcinoma. Study by laser scanning confocal microscopy.
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ROLE OF PLASMINOGEN ACTIVATOR INHIBITOR-1 IN UROKINASE'S PARADOXICAL IN VIVO TUMOR SUPPRESSING OR PROMOTING EFFECTS.
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Role of protease activated receptor-2 in lymph node metastasis of uterine cervical cancers.
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Role of squamous cell carcinoma antigen 1 expression in the invasive potential of head and neck squamous cell carcinoma.
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Role of the inflammatory protein serine protease inhibitor Kazal in preventing cytolytic granule granzyme A-mediated apoptosis.
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Role of tumor cell membrane-bound serine proteases in tumor-induced target cytolysis.
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Role of tyrosine kinase inhibitors in the treatment of pituitary tumours: from bench to bedside.
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Role of urokinase (uPA) and its receptor (uPAR) in invasion and metastasis of hormone-dependent malignancies.
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Role of urokinase-type plasminogen activator and inhibitory effect of protease inhibitor in invasion and metastasis of pancreatic cancer.
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Runt-related gene 2 in endothelial cells: inducible expression and specific regulation of cell migration and invasion.
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Salivary secretory leukocyte protease inhibitor (SLPI) and head and neck cancer: The Cancer Prevention Study II Nutrition Cohort.
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SCCA1/SERPINB3 promotes oncogenesis and epithelial-mesenchymal transition via the unfolded protein response and IL6 signaling.
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Scoring of p53, VEGF, Bcl-2 and APAF-1 immunohistochemistry and interobserver reliability in colorectal cancer.
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Screening of phytochemicals against protease activated receptor 1 (PAR1), a promising target for cancer.
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Secretion of extracellular hsp90alpha via exosomes increases cancer cell motility: a role for plasminogen activation.
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Secretory leukocyte protease inhibitor (SLPI) as a potential target for inhibiting metastasis of triple-negative breast cancers.
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Secretory leukocyte protease inhibitor (SLPI) expression and tumor invasion in oral squamous cell carcinoma.
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Secretory Leukocyte Protease Inhibitor (SLPI) in mucosal tissues: Protects against inflammation, but promotes cancer.
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Secretory Leukocyte Protease Inhibitor Expression and High-Risk HPV Infection in Anal Lesions of HIV-Positive Patients.
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Secretory leukocyte protease inhibitor inhibits infection of monocytes and lymphocytes with human immunodeficiency virus type 1 but does not interfere with transcytosis of cell-associated virus across tight epithelial barriers.
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Secretory leukocyte protease inhibitor is a survival and proliferation factor for castration-resistant prostate cancer.
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Secretory leukocyte protease inhibitor promotes the tumorigenic and metastatic potential of cancer cells.
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Secretory leukocyte protease inhibitor suppresses HPV E6-expressing HNSCC progression by mediating NF-?B and Akt pathways.
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Selecting an intervention time for intravascular enzymatic cleavage of peptide linkers to clear radioisotope from normal tissues.
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Selection criteria for epirubicin-based adjuvant chemotherapy in node-negative breast cancer.
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Selection preserves Ubiquitin Specific Protease 4 alternative exon skipping in therian mammals.
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Selective attenuation of the extrinsic limb of the tissue factor-driven coagulation protease cascade by occupancy of a novel peptidyl docking site on tissue factor.
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Selective cancer targeting with prodrugs activated by histone deacetylases and a tumour-associated protease.
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Selective function-blocking monoclonal human antibody highlights the important role of membrane type-1 matrix metalloproteinase (MT1-MMP) in metastasis.
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Selective Homogeneous Assay for Circulating Endopeptidase Fibroblast Activation Protein (FAP).
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Selective imaging of cathepsin L in breast cancer by fluorescent activity-based probes.
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Selective inhibition of NF-?B suppresses bone invasion by oral squamous cell carcinoma in vivo.
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Selective Inhibitors of Fibroblast Activation Protein (FAP) with a (4-Quinolinoyl)-glycyl-2-cyanopyrrolidine Scaffold.
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Selective targeting of lysosomal cysteine proteases with radiolabeled electrophilic substrate analogs.
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Self-Assembly of Extracellular Vesicle-like Metal-Organic Framework Nanoparticles for Protection and Intracellular Delivery of Biofunctional Proteins.
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Semi-quantitation of urokinase plasminogen activator and its receptor in breast carcinomas by immunocytochemistry.
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SENP1-mediated deSUMOylation of USP28 regulated HIF-1? accumulation and activation during hypoxia response.
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Sense and antisense cDNA transfection of CD36 (glycoprotein IV) in melanoma cells. Role of CD36 as a thrombospondin receptor.
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Sensitive determination of proteolytic proteoforms in limited microscale proteome samples.
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Seprase, a membrane-bound protease, alleviates the serum growth requirement of human breast cancer cells.
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Seprase, a membrane-bound protease, is overexpressed by invasive ductal carcinoma cells of human breast cancers.
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Sequence and conformational specificity in substrate recognition: several human Kunitz protease inhibitor domains are specific substrates of mesotrypsin.
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Sequence variation in proprotein convertase subtilisin/kexin type 9 serine protease gene, low LDL cholesterol, and cancer incidence.
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Sequential activation of murine mononuclear phagocytes for tumor cytolysis: differential expression of markers by macrophages in the several stages of development.
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Sequential production and activation of matrix-metalloproteinase-9 (MMP-9) with breast cancer progression.
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Serine peptidase inhibitor Kazal type III (SPINK3) promotes BRL-3A cell proliferation by targeting the PI3K-AKT signaling pathway.
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Serine protease hepsin regulates hepatocyte size and hemodynamic retention of tumor cells via hepatocyte growth factor signaling.
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Serine protease HtrA1 as an inhibitor on proliferation invasion and migration of gastric cancer.
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Serine protease inhibition and mitochondrial dysfunction associated with cisplatin resistance in human tumor cell lines: targets for therapy.
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Serine protease inhibitor (SERPIN) B1 suppresses cell migration and invasion in glioma cells.
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Serine protease inhibitor Kazal type 1 and epidermal growth factor receptor are expressed in pancreatic tubular adenocarcinoma, intraductal papillary mucinous neoplasm, and pancreatic intraepithelial neoplasia.
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Serine protease inhibitor Kazal type 1 promotes proliferation of pancreatic cancer cells through the epidermal growth factor receptor.
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Serine protease inhibitor kazal-type 6 inhibits tumorigenesis of human hepatocellular carcinoma cells via its extracellular action.
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Serine protease inhibitors containing a Kunitz domain: their role in modulation of host inflammatory responses and parasite survival.
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Serine protease inhibitors inhibit superoxide release and adherence in human neutrophils stimulated by granulocyte-macrophage colony-stimulating factor and tumor necrosis factor-alpha.
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Serine protease inhibitors interact with IFN-? through up-regulation of FasR; a novel therapeutic strategy against cancer.
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Serine protease PRSS23 is upregulated by estrogen receptor ? and associated with proliferation of breast cancer cells.
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Serine protease-induced enhancement of blood-borne metastasis of rat ascites tumour cells and its prevention with deoxyribonuclease.
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Serine proteases and protease-activated receptor 2-dependent allodynia: a novel cancer pain pathway.
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Serpin inhibitors of urokinase and thrombin in normal rat brain and the 9L brain tumor: evidence for elevated expression of protease nexin I-like inhibitor and a novel sodium dodecyl sulfate-activated tumor antithrombin.
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Serpin Peptidase Inhibitor Clade A Member 1 as a Potential Marker for Malignancy in Insulinomas.
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SERPINB3 protects from oxidative damage by chemotherapeutics through inhibition of mitochondrial respiratory complex I.
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SerpinB3 upregulates the Cyclooxygenase-2 / ?-Catenin positive loop in colorectal cancer.
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SERPINB5 Genetic Variants rs2289519 and rs2289521 are Significantly Associated with Gallbladder Cancer Risk.
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SerpinE2 promotes multiple cell proliferation and drug resistance in osteosarcoma.
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Serum insulin-like growth factor-I, IGF binding protein-3 and IGFBP-3 protease activity after cranial irradiation.
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Serum protease inhibitor abrogation of Newcastle disease virus enhancement of cytolysis by recombinant tumor necrosis factors alpha and beta.
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Serum protease inhibitors promote anchorage-independent growth of transformed cells in serum-free medium.
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Serum total and free prostate-specific antigen for breast cancer diagnosis in women.
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Serum tryptase, mast cells positive to tryptase and microvascular density evaluation in early breast cancer patients: possible translational significance.
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Shedding of the transferrin receptor is mediated constitutively by an integral membrane metalloprotease sensitive to tumor necrosis factor alpha protease inhibitor-2.
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Short hairpin RNA targeting of fibroblast activation protein inhibits tumor growth and improves the tumor microenvironment in a mouse model.
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ShRNA-mediated silencing of the ubiquitin-specific protease 22 gene restrained cell progression and affected the Akt pathway in nasopharyngeal carcinoma.
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Shuganyin decoction improves the intestinal barrier function in a rat model of irritable bowel syndrome induced by water-avoidance stress.
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Si113-prodrugs selectively activated by plasmin against hepatocellular and ovarian carcinoma.
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Signalling via caveolin: involvement in the cross-talk between phosphoinositolglycans and insulin.
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Significance and prognostic value of lysosomal enzyme activities measured in surgically operated adenocarcinomas of the gastroesophageal junction and squamous cell carcinomas of the lower third of esophagus.
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Significance of tumor necrosis factor (TNF) and interleukin-1 (IL-1) in the pathogenesis of fulminant hepatitis: possible involvement of serine protease in TNF-mediated liver injury.
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SIKVAV, a laminin alpha1-derived peptide, interacts with integrins and increases protease activity of a human salivary gland adenoid cystic carcinoma cell line through the ERK 1/2 signaling pathway.
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SIKVAV, a Laminin {alpha}1-Derived Peptide, Interacts with Integrins and Increases Protease Activity of a Human Salivary Gland Adenoid Cystic Carcinoma Cell Line through the ERK 1/2 Signaling Pathway.
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Similarities and differences in the biogenesis, processing and lysosomal targeting between zebrafish and human pro-Cathepsin D: functional implications.
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Simple assay for proteases based on aggregation of stimulus-responsive polypeptides.
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Simultaneous fluorescence and positron emission tomography for in vivo imaging of small animals.
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Single cell multiplexed assay for proteolytic activity using droplet microfluidics.
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Single fluorescence probes along the reactive center loop reveal site-specific changes during the latency transition of PAI-1.
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Single-dose administration of Bowman-Birk inhibitor concentrate in patients with oral leukoplakia.
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Size of native and denatured DNA of Ehrlich ascites tumour cells isolated in the presence of different protease concentrations.
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Size-transformable nanohybrids with pH/redox/enzymatic sensitivity for anticancer therapy.
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Sj7170, a unique dual-functional peptide with a specific ?-chymotrypsin inhibitory activity and a potent tumor activating effect from scorpion venom.
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SLPI knockdown induced pancreatic ductal adenocarcinoma cells proliferation and invasion.
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SLPI promotes the gastric cancer growth and metastasis by regulating the expression of P53, Bcl-2 and Caspase-8.
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Small peptides derived from the Lys active fragment of the mung bean trypsin inhibitor are fully active against trypsin.
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Sodium hydrogen exchanger and phospholipase D are required for alpha1-adrenergic receptor stimulation of metalloproteinase-9 and cellular invasion in CCL39 fibroblasts.
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Soluble Form of the (Pro)Renin Receptor Generated by Intracellular Cleavage by Furin Is Secreted in Plasma.
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Soybean Bowman-Birk Protease Inhibitor (BBI): Identification of the Mechanisms of BBI Suppressive Effect on Growth of Two Adenocarcinoma Cell Lines: AGS and HT29.
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Spatial distribution of endogenous tissue protease activity in gastric carcinoma mapped by MALDI mass spectrometry imaging.
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Specific cleavage of alpha-fodrin during Fas- and tumor necrosis factor-induced apoptosis is mediated by an interleukin-1beta-converting enzyme/Ced-3 protease distinct from the poly(ADP-ribose) polymerase protease.
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Specific cleavage of the retinoblastoma protein by an ICE-like protease in apoptosis.
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Specific Investigation of Sample Handling Effects on Protease Activities and Absolute Serum Concentrations of Various Putative Peptidome Cancer Biomarkers.
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Spectroscopic Characterization of Successive Phosphorylation of the Tissue Factor Cytoplasmic Region.
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SPINK1 is a prognosis predicting factor of non-small cell lung cancer and regulates redox homeostasis.
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SPINK1 promotes cell growth and metastasis of lung adenocarcinoma and acts as a novel prognostic biomarker.
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Spontaneous lung and lymph node metastasis in transgenic breast cancer is independent of the urokinase receptor uPAR.
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Squamous cell carcinoma of the vulva. Expression of tumor proteases cathepsin-D and pro-cathepsin-L.
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SRC family kinases: potential targets for the treatment of human cancer and leukemia.
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SST5 expression and USP8 mutation in functioning and silent corticotroph pituitary tumors.
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Stability of parathyroid hormone-related protein and parathyroid hormone at room temperature.
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Statin therapy decreases serum levels of high-sensitivity C-reactive protein and tumor necrosis factor-? in HIV-infected patients treated with ritonavir-boosted protease inhibitors.
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Steam heat with an EDTA buffer and protease digestion optimizes immunohistochemical expression of basal cell-specific antikeratin 34betaE12 to discriminate cancer in prostatic epithelium.
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Stimulated shedding of vascular cell adhesion molecule 1 (VCAM-1) is mediated by tumor necrosis factor-alpha-converting enzyme (ADAM 17).
Neoplasms
Stimulation of proteinase activated receptor-2 causes endothelial cells to promote blood coagulation in vitro.
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Stroke-induced subventricular zone proliferation is promoted by tumor necrosis factor-alpha-converting enzyme protease activity.
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Stroma-derived but not tumor ADAMTS1 is a main driver of tumor growth and metastasis.
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Stromal cell expression of components of matrix-degrading protease systems in human cancer.
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Stromal cell-derived factor-1/CXC receptor 4 and b1 integrin interaction regulates urokinase-type plasminogen activator expression in human colorectal cancer cells.
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Stromal cells as the major source for matrix metalloproteinase-2 in cutaneous melanoma.
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Stromelysin-3 expression by mammary tumor-associated fibroblasts under in vitro breast cancer cell induction.
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Strong prognostic impact of tumor-associated urokinase-type plasminogen activator in completely resected adenocarcinoma of the esophagus.
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Structural analysis of a viral ovarian tumor domain protease from the crimean-congo hemorrhagic Fever virus in complex with covalently bonded ubiquitin.
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Structural basis for proteolytic specificity of the human apoptosis-inducing granzyme M.
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Structural basis for selectivity of a small molecule, S1-binding, submicromolar inhibitor of urokinase-type plasminogen activator.
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Structural basis for the removal of ubiquitin and interferon-stimulated gene 15 by a viral ovarian tumor domain-containing protease.
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Structural modification of 4, 5-dihydro-[1, 2, 4] triazolo [4, 3-f] pteridine derivatives as BRD4 inhibitors using 2D/3D-QSAR and molecular docking analysis.
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Structure-Based Design of Selective LONP1 Inhibitors for Probing In Vitro Biology.
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Structure-based design, synthesis and SAR of a novel series of thiopheneamidine urokinase plasminogen activator inhibitors.
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Structure-based drug design of diphenyl ?-aminoalkylphosphonates as prostate-specific antigen antagonists.
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Structure-function studies on inhibitory activity of Bungarus multicinctus protease inhibitor-like protein on matrix metalloprotease-2, and invasion and migration of human neuroblastoma SK-N-SH cells.
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Structure-guided discovery of 1,3,5 tri-substituted benzenes as potent and selective matriptase inhibitors exhibiting in vivo antitumor efficacy.
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Structure?Activity Relationship and Molecular Docking of Natural Product Library Reveal Chrysin as a Novel Dipeptidyl Peptidase-4 (DPP-4) Inhibitor: An Integrated In Silico and In Vitro Study.
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Structures of CYLD USP with Met1- or Lys63-linked diubiquitin reveal mechanisms for dual specificity.
Neoplasms
Studies of Thioamide Effects on Serine Protease Activity Enable Two-Site Stabilization of Cancer Imaging Peptides.
Neoplasms
Studies on detection and analysis of proteases in leaf extract of medicinally important plants.
Neoplasms
Studies on the activity of a protease associated with cells at the advancing edge of human tumour masses in frozen sections.
Neoplasms
Studies on the mechanisms of invasion in cancer. 3. Purification of a neutral protease of rat ascites hepatoma cell associated with production of chemotactic factor for cancer cells.
Neoplasms
Studies on the mechanisms of invasion in cancer. IV. A factor associated with release of neutral protease of tumor cell.
Neoplasms
Studies related to the potential antigenicity of the Bowman-Birk inhibitor, an anticarcinogenic protease inhibitor isolated from soybeans.
Neoplasms
Study of free and complexed prostate-specific antigen in mice bearing human prostate cancer xenografts.
Neoplasms
Subtle structural differences between human and mouse PAI-1 reveal the basis for biochemical differences.
Neoplasms
Sufficiency of the reactive site loop of maspin for induction of cell-matrix adhesion and inhibition of cell invasion. Conversion of ovalbumin to a maspin-like molecule.
Neoplasms
SUMO-specific protease 2 (SENP2) functions as a tumor suppressor in osteosarcoma via SOX9 degradation.
Neoplasms
Suppression of ADAM17-mediated Lyn/Akt pathways induces apoptosis of human leukemia U937 cells: Bungarus multicinctus protease inhibitor-like protein-1 uncovers the cytotoxic mechanism.
Neoplasms
Suppression of human leukocyte tumor necrosis factor secretion by the serine protease inhibitor p-toluenesulfonyl-L-arginine methyl ester (TAME).
Neoplasms
Suppression of invasion and peritoneal carcinomatosis of ovarian cancer cell line by overexpression of bikunin.
Neoplasms
Suppression of neuroblastoma growth by dipeptidyl peptidase IV: relevance of chemokine regulation and caspase activation.
Neoplasms
Suppression of phorbol ester-enhanced radiation-induced malignancy in vitro by protease inhibitors is independent of protein kinase C.
Neoplasms
Suppression of rat breast cancer metastasis and reduction of primary tumour growth by the small synthetic urokinase inhibitor WX-UK1.
Neoplasms
Suppression of urokinase receptor expression by bikunin is associated with inhibition of upstream targets of extracellular signal-regulated kinase-dependent cascade.
Neoplasms
Suppression of urokinase-type plasminogen activator expression from human ovarian cancer cells by urinary trypsin inhibitor.
Neoplasms
Suppression subtractive hybridization to identify gene expressions in variant and classic small cell lung cancer cell lines.
Neoplasms
Synergistic antiadipogenic effects of HIV type 1 protease inhibitors with tumor necrosis factor alpha: suppression of extracellular insulin action mediated by extracellular matrix-degrading proteases.
Neoplasms
Synergistic effect of combined growth factors in porcine intervertebral disc degeneration.
Neoplasms
Synonymous variants in HTRA1 implicated in AMD susceptibility impair its capacity to regulate TGF-? signaling.
Neoplasms
Synthesis and Anticancer Activity of CDDO and CDDO-Me, Two Derivatives of Natural Triterpenoids.
Neoplasms
Synthesis and Characterization of a Novel Prostate Cancer-Targeted Phosphatidylinositol-3-kinase Inhibitor Prodrug.
Neoplasms
Synthesis and Evaluation of a CBZ-AAN-Dox Prodrug and its in vitro Effects on SiHa Cervical Cancer Cells Under Hypoxic Conditions.
Neoplasms
Synthesis and evaluation of new NIR-fluorescent probes for cathepsin B: ICT versus FRET as a turn-ON mode-of-action.
Neoplasms
Synthesis and HPLC analysis of enzymatically cleavable linker consisting of poly(ethylene glycol) and dipeptide for the development of immunoconjugate.
Neoplasms
Synthesis, solution structure, and biological evaluation of urokinase type plasminogen activator (uPA)-derived receptor binding domain mimetics.
Neoplasms
Synthetic Circuit-Driven Expression of Heterologous Enzymes for Disease Detection.
Neoplasms
Systematic analysis of proteins from different signaling pathways in the tumor center and the invasive front of colorectal cancer.
Neoplasms
Systemic cytokines, clinical and physiological changes in patients hospitalized for exacerbation of COPD.
Neoplasms
Tailor-made legumain/pH dual-responsive doxorubicin prodrug-embedded nanoparticles for efficient anticancer drug delivery and in situ monitoring of drug release.
Neoplasms
Tailoring Adjuvant Radiation Therapy by Intraoperative Imaging to Detect Residual Cancer.
Neoplasms
Target cell-directed rapid degradation of TNF-alpha messenger RNA in human cytotoxic T cells.
Neoplasms
Targeted ex vivo reduction of CD64-positive monocytes in chronic myelomonocytic leukemia and acute myelomonocytic leukemia using human granzyme B-based cytolytic fusion proteins.
Neoplasms
Targeting cell surface alpha(v)beta(3) integrin increases therapeutic efficacies of a legumain protease-activated auristatin prodrug.
Neoplasms
Targeting fibroblast activation protein (FAP): next generation PET radiotracers using squaramide coupled bifunctional DOTA and DATA5m chelators.
Neoplasms
Targeting fibroblast activation protein inhibits tumor stromagenesis and growth in mice.
Neoplasms
Targeting Inhibition of Foxp3 by MMP2/9 Sensitive Short Peptide Linked P60 Fusion Protein 6(P60-MMPs) to Enhance Antitumor Immunity.
Neoplasms
Targeting mast cells tryptase in tumor microenvironment: a potential antiangiogenetic strategy.
Neoplasms
Targeting matriptase in breast cancer abrogates tumour progression via impairment of stromal-epithelial growth factor signalling.
Neoplasms
Targeting metastatic breast cancer with peptide epitopes derived from autocatalytic loop of Prss14/ST14 membrane serine protease and with monoclonal antibodies.
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Targeting of extracellular proteases required for the progression of pancreatic cancer.
Neoplasms
Targeting plasminogen activator inhibitor-1 inhibits angiogenesis and tumor growth in a human cancer xenograft model.
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Targeting prostate cancer: Prostate-specific membrane antigen based diagnosis and therapy.
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Targeting the autolysis loop of urokinase-type plasminogen activator with conformation-specific monoclonal antibodies.
Neoplasms
Targeting the cancer stroma with a fibroblast activation protein-activated promelittin protoxin.
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Targeting the circBMPR2/miR-553/USP4 Axis as a Potent Therapeutic Approach for Breast Cancer.
Neoplasms
Targeting the intestinal TMPRSS2 protease to prevent SARS-CoV-2 entry into enterocytes-prospects and challenges.
Neoplasms
Targeting the membrane-anchored serine protease testisin with a novel engineered anthrax toxin prodrug to kill tumor cells and reduce tumor burden.
Neoplasms
Targeting the tumor proteasome as a mechanism to control the synthesis and bioactivity of matrix macromolecules.
Neoplasms
Targeting tumor cell invasion and dissemination in vivo by an aptamer that inhibits urokinase-type plasminogen activator through a novel multifunctional mechanism.
Neoplasms
Targeting ubiquitin-specific protease 22 suppresses growth and metastasis of anaplastic thyroid carcinoma.
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Targeting urokinase-type plasminogen activator and its receptor for cancer therapy.
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TASP1 mutation in a female with craniofacial anomalies, anterior segment dysgenesis, congenital immunodeficiency and macrocytic anemia.
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TASP1 Promotes Gallbladder Cancer Cell Proliferation and Metastasis by Up-regulating FAM49B via PI3K/AKT Pathway.
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Taspase1 functions as a non-oncogene addiction protease that coordinates cancer cell proliferation and apoptosis.
Neoplasms
TBX2 represses CST6 resulting in uncontrolled legumain activity to sustain breast cancer proliferation: a novel cancer-selective target pathway with therapeutic opportunities.
Neoplasms
Temporary competitive inhibition of a tumour cell surface protease as a protective mechanism in the preparation of the membrane bound native enzyme in the presence of excess cytoplasmic inhibitors.
Neoplasms
Testes-specific protease 50 (TSP50) promotes invasion and metastasis by inducing EMT in gastric cancer.
Neoplasms
Testes-specific protease 50 as an independent risk factor for poor prognosis in patients with non-small cell lung cancer.
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Testes-specific protease 50 promotes cell proliferation via inhibiting activin signaling.
Neoplasms
TF:FVIIa-specific activation of CREB upregulates proapoptotic proteins via protease-activated receptor-2.
Neoplasms
TGF-? induced PAR-1 expression promotes tumor progression and osteoclast differentiation in giant cell tumor of bone.
Neoplasms
TGF-beta1-Induced Expression of the Poor Prognosis SERPINE1/PAI-1 Gene Requires EGFR Signaling: A New Target for Anti-EGFR Therapy.
Neoplasms
The 120 kDa cell-binding fragment of fibronectin up-regulates migration of alphavbeta6-expressing cells by increasing matrix metalloproteinase-2 and -9 secretion.
Neoplasms
The 52-kDa estrogen-induced protein secreted by MCF7 cells is a lysosomal acidic protease.
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The ADAM17 Protease Promotes Tobacco Smoke Carcinogen-induced Lung Tumourigenesis.
Neoplasms
The ADAMTS12 metalloprotease gene is epigenetically silenced in tumor cells and transcriptionally activated in the stroma during progression of colon cancer.
Neoplasms
The androgen-regulated protease TMPRSS2 activates a proteolytic cascade involving components of the tumor microenvironment and promotes prostate cancer metastasis.
Neoplasms
The androgen-regulated type II serine protease TMPRSS2 is differentially expressed and mislocalized in prostate adenocarcinoma.
Neoplasms
The Anti-Cancer Potency and Mechanism of a Novel Tumor-Activated Fused Toxin, DLM.
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The Arf-like GTPase Arl8b is essential for three-dimensional invasive growth of prostate cancer in vitro and xenograft formation and growth in vivo.
Neoplasms
The association between protease inhibitors and anal cancer outcomes in veterans living with HIV treated with definitive chemoradiation: a retrospective study.
Neoplasms
The Bcl-xL and Bax-alpha control points: modulation of apoptosis induced by cancer chemotherapy and relation to TPCK-sensitive protease and caspase activation.
Neoplasms
The CAP superfamily: cysteine-rich secretory proteins, antigen 5, and pathogenesis-related 1 proteins--roles in reproduction, cancer, and immune defense.
Neoplasms
The channel-activating protease CAP1/Prss8 is required for placental labyrinth maturation.
Neoplasms
The compound 14-keto-stypodiol diacetate from the algae Stypopodium flabelliforme inhibits microtubules and cell proliferation in DU-145 human prostatic cells.
Neoplasms
The conditions for the modification of radiation transformation in vitro by a tumor promoter and protease inhibitors.
Neoplasms
The countercurrent principle in invasion and metastasis of cancer cells. Recent insights on the roles of chemokines.
Neoplasms
The cystatin M/E-cathepsin L balance is essential for tissue homeostasis in epidermis, hair follicles, and cornea.
Neoplasms
The cysteine protease domain of porcine reproductive and respiratory syndrome virus nonstructural protein 2 possesses deubiquitinating and interferon antagonism functions.
Neoplasms
The cytoplasmic tail peptide sequence of membrane type-1 matrix metalloproteinase (MT1-MMP) directly binds to gC1qR, a compartment-specific chaperone-like regulatory protein.
Neoplasms
The deubiquitinase USP34 stabilizes SOX2 and induces cell survival and drug resistance in laryngeal squamous cell carcinoma.
Neoplasms
The deubiquitinating enzyme activity of USP22 is necessary for regulating HeLa cell growth.
Neoplasms
The deubiquitylase USP15 regulates topoisomerase II alpha to maintain genome integrity.
Neoplasms
The Differential Antitumor Activity of 5-Aza-2'-deoxycytidine in Prostate Cancer DU145, 22RV1, and LNCaP Cells.
Neoplasms
The DNA hypomethylating agent, 5-aza-2'-deoxycytidine, enhances tumor cell invasion through a transcription-dependent modulation of MMP-1 expression in human fibrosarcoma cells.
Neoplasms
The dual role of the urokinase receptor system in pericellular proteolysis and cell adhesion: implications for cardiovascular function.
Neoplasms
The DUSP-Ubl domain of USP4 enhances its catalytic efficiency by promoting ubiquitin exchange.
Neoplasms
The E2F1/USP11 positive feedback loop promotes hepatocellular carcinoma metastasis and inhibits autophagy by activating ERK/mTOR pathway.
Neoplasms
The effect of 3-bromopyruvate on the properties of cathepsin B in the aspect of metastatic potential of colon cancer cells.
Neoplasms
The effect of dietary supplementation with limonene or myo-inositol on the induction of neoplasia and matrix metalloproteinase and plasminogen activator activities in accessory sex organs of male Lobund-Wistar rats.
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The effect of essential fatty acids on growth and urokinase-type plasminogen activator production in human prostate DU-145 cells.
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The effect of gamma-linolenic acid and eicosapentaenoic acid on urokinase activity.
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The effect of platelets on invasiveness and protease production of human mammary tumor cells.
Neoplasms
The EMT-related transcription factor snail up-regulates FAP? in malignant melanoma cells.
Neoplasms
The ER-positive/PgR-negative breast cancer phenotype is not associated with mutations within the DNA binding domain.
Neoplasms
The ERK/MAPK pathway regulates the activity of the human tissue factor pathway inhibitor-2 promoter.
Neoplasms
The expression of E-cadherin and cathepsin-D in normal oral mucosa, oral epithelial dysplasia and oral squamous cell carcinoma: A comparative analysis between immunohistochemistry and routine histopathology.
Neoplasms
The expression of the ADAMs proteases in prostate cancer cell lines and their regulation by dihydrotestosterone.
Neoplasms
The extracellular matrix of hybrids between melanoma cells and normal fibroblasts.
Neoplasms
The Functionalized Human Serine Protease Granzyme B/VEGF121 Targets Tumor Vasculature and Ablates Tumor Growth.
Neoplasms
The gene for fibroblast activation protein alpha (FAP), a putative cell surface-bound serine protease expressed in cancer stroma and wound healing, maps to chromosome band 2q23.
Neoplasms
The growth inhibitory effect of mesenchymal stem cells on tumor cells in vitro and in vivo.
Neoplasms
The HAUSP gene plays an important role in non-small cell lung carcinogenesis through p53-dependent pathways.
Neoplasms
The HIV protease inhibitor saquinavir induces endoplasmic reticulum stress, autophagy, and apoptosis in ovarian cancer cells.
Neoplasms
The human immunodeficiency virus (HIV)-1 protease inhibitor saquinavir inhibits proteasome function and causes apoptosis and radiosensitization in non-HIV-associated human cancer cells.
Neoplasms
The hyaluronan-binding protease upregulates ERK1/2 and PI3K/Akt signalling pathways in fibroblasts and stimulates cell proliferation and migration.
Neoplasms
The Immune Profile of Pituitary Adenomas and a Novel Immune Classification for Predicting Immunotherapy Responsiveness.
Neoplasms
The Impact of Nelfinavir Exposure on Cancer Development Among a Large Cohort of HIV-Infected Patients.
Neoplasms
The induction of Maspin expression by a glucosamine-derivative has an antiproliferative activity in prostate cancer cell lines.
Neoplasms
The influence of matriptase-2 on prostate cancer in vitro: A possible role for ?-catenin.
Neoplasms
The influence of the protease inhibitor aprotinin on tumor invasion of three cell lines in vitro.
Neoplasms
The inhibition of a tumour cell surface protease in vivo and its re-activation by oxidation.
Neoplasms
The insulin-like growth factor system in human immunodeficiency virus infection: relations to immunological parameters, disease progression, and antiretroviral therapy.
Neoplasms
The interaction of HGF-SF with other cytokines in tumor invasion and angiogenesis.
Neoplasms
The interaction of plasminogen activator with a reconstituted basement membrane matrix and extracellular macromolecules produced by cultured epithelial cells.
Neoplasms
The involvement of calpain-dependent proteolysis of the tumor suppressor NF2 (merlin) in schwannomas and meningiomas.
Neoplasms
The Iron Chelator, Dp44mT, Effectively Inhibits Human Oral Squamous Cell Carcinoma Cell Growth in Vitro and in Vivo.
Neoplasms
The levels of alpha 1-antitrypsin and alpha 1-antichymotrypsin in the sera of patients with gastrointestinal cancers during diagnosis.
Neoplasms
The miR-27a-3p/USP25 axis participates in the pathogenesis of recurrent miscarriage by inhibiting trophoblast migration and invasion.
Neoplasms
The Mitochondrial Unfoldase-Peptidase Complex ClpXP Controls Bioenergetics Stress and Metastasis.
Neoplasms
The molecular biology of colorectal cancer development and the associated genetic events.
Neoplasms
The molecular function of kallikrein-related peptidase 14 demonstrates a key modulatory role in advanced prostate cancer.
Neoplasms
The mRNA coding for the secreted protease transin is expressed more abundantly in malignant than in benign tumors.
Neoplasms
The multi-functional serpin, protein C inhibitor: beyond thrombosis and hemostasis.
Neoplasms
The mutation spectrum of the EDA gene in X-linked anhidrotic ectodermal dysplasia.
Neoplasms
The N-terminal cysteine protease domain of rice stripe tenuivirus Pc1 possesses deubiquitinating enzyme activity.
Neoplasms
The N-terminal domain plays a crucial role in the structure of a full-length human mitochondrial Lon protease.
Neoplasms
The novel serine protease tumor-associated differentially expressed gene-15 (matriptase/MT-SP1) is highly overexpressed in cervical carcinoma.
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The Opportunity of Precision Medicine for Breast Cancer With Context-Sensitive Tumor Suppressor Maspin.
Neoplasms
The p38 SAPK pathway is required for Ha-ras induced in vitro invasion of NIH3T3 cells.
Neoplasms
The p42 variant of ETS1 protein rescues defective Fas-induced apoptosis in colon carcinoma cells.
Neoplasms
The pathogenesis of venous thromboembolism in cancer: emerging links with tumour biology.
Neoplasms
The pattern of Protease Activated Receptor 1 (PAR1) expression in endometrial carcinoma.
Neoplasms
The phosphorylated and/or sulfated structure of the carbohydrate-protein-linkage region isolated from chondroitin sulfate in the hybrid proteoglycans of Engelbreth-Holm-Swarm mouse tumor.
Neoplasms
The presence of elafin, SLPI, IL1-RA and STNFalpha RI in head and neck squamous cell carcinomas and their relation to the degree of tumour differentiation.
Neoplasms
The process of macrophage migration promotes matrix metalloproteinase-independent invasion by tumor cells.
Neoplasms
The promoter and the enhancer region of the KLK 3 (prostate specific antigen) gene is frequently mutated in breast tumours and in breast carcinoma cell lines.
Neoplasms
The protease activated receptor 1 gene variation IVSn -14A>T is associated with distant metastasis and cancer-specific survival in renal cell carcinoma.
Neoplasms
The Protease Activated Receptor2 Promotes Rab5a Mediated Generation of Pro-metastatic Microvesicles.
Neoplasms
The protease and antiprotease of plasmas of patients with cancer and other diseases.
Neoplasms
The protease consortium: an alliance to advance the understanding of proteolytic enzymes as therapeutic targets for cancer.
Neoplasms
The protease inhibitor, elafin, induces p53-dependent apoptosis in human melanoma cells.
Neoplasms
The protease-inhibitor SerpinB3 as a critical modulator of the stem-like subset in human cholangiocarcinoma.
Neoplasms
The proteolytic profile of human cancer procoagulant suggests that it promotes cancer metastasis at the level of activation rather than degradation.
Neoplasms
The Relationship between Vascular Endothelial Growth Factor 1154G/A Polymorphism and Recurrent Implantation Failure.
Neoplasms
The road to integrative cancer therapies: emergence of a tumor-associated fibroblast protease as a potential therapeutic target in cancer.
Neoplasms
The role of annexin II in angiogenesis and tumor progression: a potential therapeutic target.
Neoplasms
The role of atorvastatin in regulating the immune response leading to vascular damage in a model of Kawasaki disease.
Neoplasms
The role of cancer cell protease in invasion of rat ascites hepatome AH 109 A cells, with special reference to pulmonary metastasis of subcutaneously transplanted cells.
Neoplasms
The role of cell adhesion molecules and proteases in tumor invasion and metastasis.
Neoplasms
The role of endocytic Rab GTPases in regulation of growth factor signaling and the migration and invasion of tumor cells.
Neoplasms
The role of nutraceutical proteins and peptides in apoptosis, angiogenesis, and metastasis of cancer cells.
Neoplasms
The Role of Protease-Activated Receptor 2 in Hepatocellular Carcinoma after Hepatectomy.
Neoplasms
The role of steroid contraceptive hormones in the pathogenesis of invasive cervical cancer: a review.
Neoplasms
The role of the acute-phase protein alpha 1-antichymotrypsin in brain dysfunction and injury.
Neoplasms
The role of the deubiquitinating enzyme DUB3/USP17 in cancer: a narrative review.
Neoplasms
The role of the disintegrin metalloproteinase ADAM15 in prostate cancer progression.
Neoplasms
The role of tissue inhibitors of metalloproteinases in tumorigenesis and metastasis.
Neoplasms
The role of urokinase-type plasminogen activator and its inhibitor PAI-1 in gastric cancer.
Neoplasms
The secreted protein ANGPTL2 promotes metastasis of osteosarcoma cells through integrin ?5?1, p38 MAPK, and matrix metalloproteinases.
Neoplasms
The secretory leukocyte protease inhibitor (SLPI) suppresses cancer cell invasion but promotes blood-borne metastasis via an invasion-independent pathway.
Neoplasms
The secretory leukocyte protease inhibitor gene is a target of epidermal growth factor receptor action in endometrial epithelial cells.
Neoplasms
The Secretory Leukocyte Protease Inhibitor Is a Type 1 Insulin-Like Growth Factor Receptor-Regulated Protein that Protects against Liver Metastasis by Attenuating the Host Proinflammatory Response.
Neoplasms
The serine protease inhibitor protease nexin-1 controls mammary cancer metastasis through LRP-1-mediated MMP-9 expression.
Neoplasms
The serine protease stratum corneum chymotryptic enzyme (kallikrein 7) is highly overexpressed in squamous cervical cancer cells.
Neoplasms
The surface of prostate carcinoma DU145 cells mediates the inhibition of urokinase-type plasminogen activator by maspin.
Neoplasms
The TGF-alpha precursor expressed on the cell surface binds to the EGF receptor on adjacent cells, leading to signal transduction.
Neoplasms
The thymus-specific serine protease TSSP/PRSS16 is crucial for the antitumoral role of CD4(+) T cells.
Neoplasms
The Transcription Factor ERG Regulates Super-Enhancers Associated With an Endothelial-Specific Gene Expression Program.
Neoplasms
The Treponema denticola surface protease dentilisin degrades interleukin-1beta (IL-1beta), IL-6, and tumor necrosis factor alpha.
Neoplasms
The Tumor Proteolytic Landscape: A Challenging Frontier in Cancer Diagnosis and Therapy.
Neoplasms
The tumor suppressor maspin does not undergo the stressed to relaxed transition or inhibit trypsin-like serine proteases. Evidence that maspin is not a protease inhibitory serpin.
Neoplasms
The tumor suppressor maspin mediates E2F1-induced sensitivity of cancer cells to chemotherapy.
Neoplasms
The ubiquitin-proteasome system in prostate cancer and its transition to castration resistance.
Neoplasms
The ubiquitin-specific protease USP2a enhances tumor progression by targeting cyclin A1 in bladder cancer.
Neoplasms
The urokinase plasminogen activating system in thyroid cancer: clinical implications.
Neoplasms
The urokinase plasminogen activator system in breast cancer invasion and metastasis.
Neoplasms
The urokinase receptor (uPAR, CD87) as a target for tumor therapy: uPA-silica particles (SP-uPA) as a new tool for assessing synthetic peptides to interfere with uPA/uPA-receptor interaction.
Neoplasms
The urokinase receptor promotes cancer metastasis independently of urokinase-type plasminogen activator in mice.
Neoplasms
The urokinase receptor: focused cell surface proteolysis, cell adhesion and signaling.
Neoplasms
The urokinase-system in tumor tissue stroma of the breast and breast cancer cell invasion.
Neoplasms
The USP8 mutational status may predict long-term remission in patients with Cushing's disease.
Neoplasms
The vOTU domain of highly-pathogenic porcine reproductive and respiratory syndrome virus displays a differential substrate preference.
Neoplasms
Theranostic Layer-by-Layer Nanoparticles for Simultaneous Tumor Detection and Gene Silencing.
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Therapeutic efficacy of once-daily oral administration of a Kunitz-type protease inhibitor, bikunin, in a mouse model and in human cancer.
Neoplasms
Therapeutic nanomedicine based on dual-intelligent functionalized gold nanoparticles for cancer imaging and therapy in vivo.
Neoplasms
Therapeutic Potential of Medicinal Plant Proteins: Present Status and Future Perspectives.
Neoplasms
Thioredoxin Mediates Remodeling Factors of Human Bronchial Epithelial Cells upon Interaction with House Dust Mite-Stimulated Eosinophils.
Neoplasms
Three Female Familial Cases of Solid Pseudopapillary Tumors With a Protease Serine 1 Gene Mutation.
Neoplasms
Thrombin enhances degradation of heparan sulfate in the extracellular matrix by tumor cell heparanase.
Neoplasms
Thrombin induces osteosarcoma growth, a function inhibited by low molecular weight heparin in vitro and in vivo: Procoagulant nature of osteosarcoma.
Neoplasms
Thrombin induces tumor invasion through the induction and association of matrix metalloproteinase-9 and beta1-integrin on the cell surface.
Neoplasms
Thrombomodulin, a receptor for the serine protease thrombin, is decreased in primary tumors and metastases but increased in ascitic fluids of patients with advanced ovarian cancer FIGO IIIc.
Neoplasms
Time-domain in vivo near infrared fluorescence imaging for evaluation of matriptase as a potential target for the development of novel, inhibitor-based tumor therapies.
Neoplasms
Timp3 deficiency affects the progression of DEN-related hepatocellular carcinoma during diet-induced obesity in mice.
Neoplasms
Timp3 loss accelerates tumour invasion and increases prostate inflammation in a mouse model of prostate cancer.
Neoplasms
Tissue and plasma elastase and anti-protease (alpha 1 protease inhibitor-alpha 2 macroglobulin) levels in malignancies of head and neck.
Neoplasms
Tissue factor pathway inhibitor 2 is a potent kallikrein-related protease 12 inhibitor.
Neoplasms
Tissue factor pathway inhibitor?2 is specifically expressed in ovarian clear cell carcinoma tissues in the nucleus, cytoplasm and extracellular matrix.
Neoplasms
Tissue factor: A potent stimulator of Von Willebrand factor synthesis by human umbilical vein endothelial cells.
Neoplasms
Tissue inhibitor of metalloproteinases-1-induced scattered liver metastasis is mediated by host-derived urokinase-type plasminogen activator.
Neoplasms
Tissue inhibitor of metalloproteinases-2 inhibits bFGF-induced human microvascular endothelial cell proliferation.
Neoplasms
Tissue microarrays of human tumor xenografts: characterization of proteins involved in migration and angiogenesis for applications in the development of targeted anticancer agents.
Neoplasms
Tissue plasminogen activator induces pancreatic cancer cell proliferation by a non-catalytic mechanism that requires extracellular signal-regulated kinase 1/2 activation through epidermal growth factor receptor and annexin A2.
Neoplasms
TL1, a novel tumor necrosis factor-like cytokine, induces apoptosis in endothelial cells. Involvement of activation of stress protein kinases (stress-activated protein kinase and p38 mitogen-activated protein kinase) and caspase-3-like protease.
Neoplasms
TLS-CHOP represses miR-486 expression, inducing upregulation of a metastasis regulator PAI-1 in human myxoid liposarcoma.
Neoplasms
TMPRSS2, a Serine Protease Expressed in the Prostate on the Apical Surface of Luminal Epithelial Cells and Released into Semen in Prostasomes, Is Misregulated in Prostate Cancer Cells.
Neoplasms
TMPRSS4 as an emerging potential poor prognostic factor for solid tumors: A systematic review and meta-analysis.
Neoplasms
TMPRSS4 facilitates epithelial-mesenchymal transition of hepatocellular carcinoma and is a predictive marker for poor prognosis of patients after curative resection.
Neoplasms
TMPRSS4 Promotes Cell Proliferation and Inhibits Apoptosis in Pancreatic Ductal Adenocarcinoma by Activating ERK1/2 Signaling Pathway.
Neoplasms
TMPRSS4 promotes invasiveness of human gastric cancer cells through activation of NF-?B/MMP-9 signaling.
Neoplasms
TMPRSS4 regulates levels of integrin ?5 in NSCLC through miR-205 activity to promote metastasis.
Neoplasms
TMPRSS4 Upregulates TWIST1 Expression through STAT3 Activation to Induce Prostate Cancer Cell Migration.
Neoplasms
TRAF6 Plays a Proviral Role in Tick-Borne Flavivirus Infection through Interaction with the NS3 Protease.
Neoplasms
Transcriptional and posttranscriptional activation of urokinase plasminogen activator gene expression in metastatic tumor cells.
Neoplasms
Transcriptional Regulation of Seprase in Invasive Melanoma Cells by Transforming Growth Factor-? Signaling.
Neoplasms
Transcriptional regulation of urokinase (uPA) gene expression in breast cancer cells: role of DNA methylation.
Neoplasms
Transformation by oncogenic ras-p21 alters the processing and subcellular localization of the lysosomal protease cathepsin D.
Neoplasms
Transient alterations in the expression of protease and extracellular matrix genes during metastatic lung colonization by H-ras-transformed 10T1/2 fibroblasts.
Neoplasms
Transient denervation of viable myocardium after myocardial infarction does not alter arrhythmia susceptibility.
Neoplasms
Transmembrane protease serine 4 promotes thyroid cancer proliferation via CREB phosphorylation.
Neoplasms
Transmembrane Protease TMPRSS11B Promotes Lung Cancer Growth by Enhancing Lactate Export and Glycolytic Metabolism.
Neoplasms
Treatment with field bean protease inhibitor can effectively repress ethylnitrosourea (ENU)-induced neoplasms of the nervous system in Sprague-Dawley rats.
Neoplasms
Trichinella pseudospiralis infection is characterized by more continuous and diffuse myopathy than T. spiralis infection.
Neoplasms
Tricho-rhino-phalangeal syndrome 1 protein functions as a scaffold required for ubiquitin-specific protease 4-directed histone deacetylase 2 de-ubiquitination and tumor growth.
Neoplasms
TRIM11 activates the proteasome and promotes overall protein degradation by regulating USP14.
Neoplasms
Tripeptidyl peptidase II plays a role in the radiation response of selected primary cell types but not based on nuclear translocation and p53 stabilization.
Neoplasms
Trp(250) -hK2 is defective in intracellular trafficking and activates the unfolded protein response.
Neoplasms
Truncated Human Cathepsin L, Encoded by a Novel Splice Variant, Exhibits Altered Subcellular Localization and Cytotoxicity.
Neoplasms
Tryptase serum levels in patients suffering from hepatocellular carcinoma undergoing intra-arterial chemoembolization: Possible predictive role of response to treatment.
Neoplasms
Tryptase-positive mast cells correlate with angiogenesis in early breast cancer patients.
Neoplasms
TSP50 Depends on Its Threonine Protease Activity and Its Interactions with TNF-?-Induced NF-?B for Its Role in Human Cervical Tumorigenesis.
Neoplasms
TSP50 promotes hepatocyte proliferation and tumour formation by activating glucose-6-phosphate dehydrogenase (G6PD).
Neoplasms
Tumor cell collagenase and its inhibition by a cartilage-derived protease inhibitor.
Neoplasms
Tumor cell interactions with the extracellular matrix during invasion and metastasis.
Neoplasms
Tumor Cell Invasion Induced by Radiation in Balb/C Mouse is Prevented by the Cox-2 Inhibitor NS-398.
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Tumor cell invasion is promoted by activation of protease activated receptor-1 in cooperation with the alpha vbeta 5 integrin.
Neoplasms
Tumor cell resistance to apoptosis due to a defect in the activation of sphingomyelinase and the 24 kDa apoptotic protease (AP24).
Neoplasms
Tumor cell-derived Timp-1 is necessary for maintaining metastasis-promoting Met-signaling via inhibition of Adam-10.
Neoplasms
Tumor necrosis factor alpha-converting enzyme mediates MUC5AC mucin expression in cultured human airway epithelial cells.
Neoplasms
Tumor necrosis factor-alpha-converting enzyme (ADAM17) mediates the cleavage and shedding of fractalkine (CX3CL1).
Neoplasms
Tumor necrosis factor-alpha-converting enzyme (TACE/ADAM-17) mediates the ectodomain cleavage of intercellular adhesion molecule-1 (ICAM-1).
Neoplasms
Tumor necrosis factor-induced apoptosis stimulates p53 accumulation and p21WAF1 proteolysis in ME-180 cells.
Neoplasms
Tumor suppressive microRNA-124a inhibits stemness and enhances gefitinib sensitivity of non-small cell lung cancer cells by targeting ubiquitin-specific protease 14.
Neoplasms
Tumor suppressor cell adhesion molecule 1 (CADM1) is cleaved by a disintegrin and metalloprotease 10 (ADAM10) and subsequently cleaved by ?-secretase complex.
Neoplasms
Tumor suppressor maspin is up-regulated during keratinocyte senescence, exerting a paracrine antiangiogenic activity.
Neoplasms
Tumor transcriptome reveals the predictive and prognostic impact of lysosomal protease inhibitors in non-small-cell lung cancer.
Neoplasms
Tumor-associated proteases and inhibitors in gastric cancer: analysis of prognostic impact and individual risk protease patterns.
Neoplasms
Tumor-associated trypsin participates in cancer cell-mediated degradation of extracellular matrix.
Neoplasms
Tumor-conditional anti-CTLA4 uncouples antitumor efficacy from immunotherapy-related toxicity.
Neoplasms
Tumor-host interactions contribute to the elevated expression level of alpha1-antichymotrypsin in metastatic breast tumor xenografts.
Neoplasms
Tumor-Penetrating Hierarchically Structured Nanomarker for Imaging-Guided Urinary Monitoring of Cancer.
Neoplasms
Tumor-Recruited Neutrophils and Neutrophil TIMP-Free MMP-9 Regulate Coordinately the Levels of Tumor Angiogenesis and Efficiency of Malignant Cell Intravasation.
Neoplasms
Tumor-stroma interactions directing phenotype and progression of epithelial skin tumor cells.
Neoplasms
Tumor-suppressive maspin regulates cell response to oxidative stress by direct interaction with glutathione S-transferase.
Neoplasms
Tumoral and macrophage uPAR and MMP-9 contribute to the invasiveness of B16 murine melanoma cells.
Neoplasms
Tumour but not stromal expression of ?3 integrin is essential, and is required early, for spontaneous dissemination of bone-metastatic breast cancer.
Neoplasms
Tumour necrosis factor ? secretion induces protease activation and acinar cell necrosis in acute experimental pancreatitis in mice.
Neoplasms
Tumour suppression by targeted intravenous non-viral CRISPRa using dendritic polymers.
Neoplasms
Tumour-associated fibrinolysis: the prognostic relevance of plasminogen activators uPA and tPA in human breast cancer.
Neoplasms
Tumour-associated urokinase-type plasminogen activator (uPA) and its inhibitor PAI-1 in normal and neoplastic tissues of patients with squamous cell cancer of the oral cavity - clinical relevance and prognostic value.
Neoplasms
Tuning Cellular Uptake of Molecular Probes by Rational Design of Their Assembly into Supramolecular Nanoprobes.
Neoplasms
Twenty-five-year panorama of corneal immunology: emerging concepts in the immunopathogenesis of microbial keratitis, peripheral ulcerative keratitis, and corneal transplant rejection.
Neoplasms
Tyrosine phosphorylation of maspin in normal mammary epithelia and breast cancer cells.
Neoplasms
U94 alters FN1 and ANGPTL4 gene expression and inhibits tumorigenesis of prostate cancer cell line PC3.
Neoplasms
Ubiquitin C-terminal hydrolase-l1 activity induces polyubiquitin accumulation in podocytes and increases proteinuria in rat membranous nephropathy.
Neoplasms
Ubiquitin specific peptidase 33 promotes cell proliferation and reduces apoptosis through regulation of the SP1/PI3K/AKT pathway in retinoblastoma.
Neoplasms
Ubiquitin specific protease 2 acts as a key modulator for the regulation of cell cycle by adiponectin and leptin in cancer cells.
Neoplasms
Ubiquitin specific protease 22 promotes cell proliferation and tumor growth of epithelial ovarian cancer through synergy with transforming growth factor ?1.
Neoplasms
Ubiquitin Specific Protease 29 Functions as an Oncogene Promoting Tumorigenesis in Colorectal Carcinoma.
Neoplasms
Ubiquitin-Specific Peptidase 10 (USP10) Inhibits Hepatic Steatosis, Insulin Resistance, and Inflammation Through Sirt6.
Neoplasms
Ubiquitin-specific peptidase 39 promotes human glioma cells migration and invasion by facilitating ADAM9 mRNA maturation.
Neoplasms
Ubiquitin-specific peptidase 46 (USP46) suppresses renal cell carcinoma tumorigenesis through AKT pathway inactivation.
Neoplasms
Ubiquitin-specific protease 11 (USP11) functions as a tumor suppressor through deubiquitinating and stabilizing VGLL4 protein.
Neoplasms
Ubiquitin-specific protease 11 functions as a tumor suppressor by modulating Mgl-1 protein to regulate cancer cell growth.
Neoplasms
Ubiquitin-specific protease 14 (USP14) promotes proliferation and metastasis in pancreatic ductal adenocarcinoma.
Neoplasms
Ubiquitin-specific protease 14 regulates cell proliferation and apoptosis in oral squamous cell carcinoma.
Neoplasms
Ubiquitin-specific protease 14 regulates ovarian cancer cisplatin-resistance by stabilizing BCL6 oncoprotein.
Neoplasms
Ubiquitin-specific protease 15 contributes to gastric cancer progression by regulating the Wnt/?-catenin signaling pathway.
Neoplasms
Ubiquitin-specific protease 15 promotes tumor cell invasion and proliferation in glioblastoma.
Neoplasms
Ubiquitin-specific protease 21 stabilizes BRCA2 to control DNA repair and tumor growth.
Neoplasms
Ubiquitin-specific protease 22 acts as an oncoprotein to maintain glioma malignancy through deubiquitinating B cell-specific Moloney murine leukemia virus integration site 1 for stabilization.
Neoplasms
Ubiquitin-specific protease 22 enhances intestinal cell proliferation and tissue regeneration after intestinal ischemia reperfusion injury.
Neoplasms
Ubiquitin-specific protease 22 is associated with poor prognosis in neuroblastoma.
Neoplasms
Ubiquitin-specific protease 22 promotes the proliferation, migration and invasion of glioma cells.
Neoplasms
Ubiquitin-specific protease 22: a novel molecular biomarker in cervical cancer prognosis and therapeutics.
Neoplasms
Ubiquitin-specific protease 22: a novel molecular biomarker in glioma prognosis and therapeutics.
Neoplasms
Ubiquitin-specific protease 39 is overexpressed in human lung cancer and promotes tumor cell proliferation in vitro.
Neoplasms
Ubiquitin-specific protease 4 (USP4) targets TRAF2 and TRAF6 for deubiquitination and inhibits TNF?-induced cancer cell migration.
Neoplasms
Ubiquitin-specific protease 4 predicts an unfavorable prognosis and promotes malignant behaviors in vitro in pancreatic cancer.
Neoplasms
Ubiquitin-specific protease 4 promotes glioblastoma multiforme via activating ERK pathway.
Neoplasms
Ubiquitin-specific protease 4 promotes hepatocellular carcinoma progression via cyclophilin A stabilization and deubiquitination.
Neoplasms
Ubiquitin-Specific Protease 6 Functions as a Tumor Suppressor in Ewing Sarcoma through Immune Activation.
Neoplasms
Ubiquitin-specific protease 8 inhibitor suppresses adrenocorticotropic hormone production and corticotroph tumor cell proliferation.
Neoplasms
Ubiquitin-specific protease-44 inhibits the proliferation and migration of cells via inhibition of JNK pathway in clear cell renal cell carcinoma.
Neoplasms
Ubiquitin?specific protease 22?induced autophagy is correlated with poor prognosis of pancreatic cancer.
Neoplasms
UBP5 encodes a putative yeast ubiquitin-specific protease that is related to the human Tre-2 oncogene product.
Neoplasms
Ulinastatin, a protease inhibitor, may inhibit allogeneic blood transfusion-associated pro-inflammatory cytokines and systemic inflammatory response syndrome and improve postoperative recovery.
Neoplasms
Unique antineoplastic profile of Saquinavir-NO, a novel NO-derivative of the protease inhibitor Saquinavir, on the in vitro and in vivo tumor formation of A375 human melanoma cells.
Neoplasms
Unique proliferation-associated marker expressed on activated and transformed human cells defined by monoclonal antibody.
Neoplasms
Up-regulation of Flotillin-2 is associated with melanoma progression and modulates expression of the thrombin receptor protease activated receptor 1.
Neoplasms
Up-regulation of TNF-alpha convertase (TACE/ADAM17) after oxygen-glucose deprivation in rat forebrain slices.
Neoplasms
Up-regulation of urokinase-type plasminogen activator expression by the HER2/neu proto-oncogene.
Neoplasms
uPA and PAI-1 as biomarkers in breast cancer: validated for clinical use in level-of-evidence-1 studies.
Neoplasms
uPA-silica-Particles (SP-uPA): a novel analytical system to investigate uPA-uPAR interaction and to test synthetic uPAR antagonists as potential cancer therapeutics.
Neoplasms
Upregulation of apoptotic protease activating factor-1 expression correlates with anti-tumor effect of taxane drug.
Neoplasms
Upregulation of kallikrein?related peptidase 5 is associated with the malignant behavior of colorectal cancer.
Neoplasms
Upregulation of maspin expression in human cervical carcinoma cells by transforming growth factor ?1 through the convergence of Smad and non-Smad signaling pathways.
Neoplasms
Upregulation of tissue kallikrein, kinin B1 receptor, and kinin B2 receptor in mast and giant cells infiltrating oesophageal squamous cell carcinoma.
Neoplasms
Urinary trypsin inhibitor, a Kunitz-type protease inhibitor, modulates tumor necrosis factor-stimulated activation and translocation of protein kinase C in U937 cells.
Neoplasms
Urokinase (uPA) and its inhibitor PAI-1 are strong and independent prognostic factors in node-negative breast cancer.
Neoplasms
Urokinase expression in course of benign and malignant mammary lesions: comparison between nodular and healthy tissues.
Neoplasms
Urokinase plasminogen activator and urokinase plasminogen activator receptor in breast cancer.
Neoplasms
Urokinase plasminogen activator as a prognostic marker in different subgroups of patients with breast cancer.
Neoplasms
Urokinase Plasminogen Activator System Targeted Delivery of Nanobins as a Novel Ovarian Cancer Therapeutics.
Neoplasms
Urokinase plasminogen activator: a prognostic marker in breast cancer including patients with axillary node-negative disease.
Neoplasms
Urokinase plasminogen activator: a prognostic marker in multiple types of cancer.
Neoplasms
Urokinase receptor antibody can reduce tumor volume and detect the presence of occult tumor metastases in vivo.
Neoplasms
Urokinase receptor localization in breast cancer and benign lesions assessed by in situ hybridization and immunohistochemistry.
Neoplasms
Urokinase signaling through its receptor protects against anoikis by increasing BCL-xL expression levels.
Neoplasms
Urokinase system expression in gastric carcinoma: prognostic impact in an independent patient series and first evidence of predictive value in preoperative biopsy and intestinal metaplasia specimens.
Neoplasms
Urokinase-mediated recruitment of myeloid-derived suppressor cells and their suppressive mechanisms are blocked by MUC1/sec.
Neoplasms
Urokinase-plasminogen activator in breast cancer: assay by both catalytic and immunoassay.
Neoplasms
Urokinase-plasminogen activator, a new and independent prognostic marker in breast cancer.
Neoplasms
Urokinase-type plasminogen activator (uPA) and its receptor (uPAR): development of antagonists of uPA/uPAR interaction and their effects in vitro and in vivo.
Neoplasms
Urokinase-type plasminogen activator in colorectal cancer: relationship with clinicopathological features and patient outcome.
Neoplasms
Urokinase-type plasminogen activator, its inhibitor, and its receptor in patients with upper urinary tract carcinoma.
Neoplasms
Urokinase-type plasminogen activator: a potent marker of metastatic potential in human cancers.
Neoplasms
Use of a macrophage cytotoxicity system to show macrophage activation by Listeria monocytogenes cell wall fraction.
Neoplasms
USP1 links platinum resistance to cancer cell dissemination by regulating Snail stability.
Neoplasms
USP10 regulates Musashi-2 stability via deubiquitination and promotes tumour proliferation in colon cancer.
Neoplasms
USP10 suppresses tumor progression by inhibiting mTOR activation in hepatocellular carcinoma.
Neoplasms
USP11 facilitates colorectal cancer proliferation and metastasis by regulating IGF2BP3 stability.
Neoplasms
USP11 promotes growth and metastasis of colorectal cancer via PPP1CA-mediated activation of ERK/MAPK signaling pathway.
Neoplasms
USP17-mediated de-ubiquitination and cancer: Clients cluster around the cell cycle.
Neoplasms
USP18 promotes cell proliferation and suppressed apoptosis in cervical cancer cells via activating AKT signaling pathway.
Neoplasms
USP2 promotes cell migration and invasion in triple negative breast cancer cell lines.
Neoplasms
USP21 promotes cell proliferation and metastasis through suppressing EZH2 ubiquitination in bladder carcinoma.
Neoplasms
USP21 upregulation in cholangiocarcinoma promotes cell proliferation and migration in a deubiquitinase-dependent manner.
Neoplasms
USP22 acts as an oncogene by regulating the stability of cyclooxygenase-2 in non-small cell lung cancer.
Neoplasms
Usp22 is expressed in mouse uterus during early pregnancy and involved in endometrial stromal cell decidualization.
Neoplasms
USP22 maintains gastric cancer stem cell stemness and promotes gastric cancer progression by stabilizing BMI1 protein.
Neoplasms
USP22 promotes resistance to EGFR-TKIs by preventing ubiquitination-mediated EGFR degradation in EGFR-mutant lung adenocarcinoma.
Neoplasms
USP22 Suppresses SPARC Expression in Acute Colitis and Inflammation-Associated Colorectal Cancer.
Neoplasms
USP22 transcriptional activity is negatively regulated by the histone deacetylase inhibitor trichostatin A.
Neoplasms
USP22-dependent HSP90AB1 expression promotes resistance to HSP90 inhibition in mammary and colorectal cancer.
Neoplasms
USP32 is an active, membrane-bound ubiquitin protease overexpressed in breast cancers.
Neoplasms
USP33 regulates c-Met expression by deubiquitinating SP1 to facilitate metastasis in hepatocellular carcinoma.
Neoplasms
USP39 mediates p21-dependent proliferation and neoplasia of colon cancer cells by regulating the p53/p21/CDC2/cyclin B1 axis.
Neoplasms
USP39, a direct target of microRNA-133a, promotes progression of pancreatic cancer via the AKT pathway.
Neoplasms
USP48 Is Upregulated by Mettl14 to Attenuate Hepatocellular Carcinoma via Regulating SIRT6 Stabilization.
Neoplasms
USP5 Promotes Metastasis in Non-Small Cell Lung Cancer by Inducing Epithelial-Mesenchymal Transition via Wnt/?-Catenin Pathway.
Neoplasms
USP5 promotes tumorigenesis and progression of pancreatic cancer by stabilizing FoxM1 protein.
Neoplasms
USP5 Promotes Uterine Corpus Endometrial Carcinoma Cell Growth and Migration via mTOR/4EBP1 Activation.
Neoplasms
USP6 Confers Sensitivity to IFN-Mediated Apoptosis through Modulation of TRAIL Signaling in Ewing Sarcoma.
Neoplasms
USP9X mRNA expression predicts clinical outcome for esophageal squamous cell carcinoma treated with cisplatin-based therapy.
Neoplasms
USP9X stabilizes BRCA1 and confers resistance to DNA-damaging agents in human cancer cells.
Neoplasms
Utility of TMPRSS4 as a Prognostic Biomarker and Potential Therapeutic Target in Patients with Gastric Cancer.
Neoplasms
UV radiation promotes melanoma dissemination mediated by the sequential reaction axis of cathepsins-TGF-?1-FAP-?.
Neoplasms
Validation of immunolocalization of the urokinase receptor expression in ductal carcinoma in situ of the breast: comparison with detection by non-isotopic in-situ hybridization.
Neoplasms
Venom gland transcriptome from Heloderma horridum horridum by high-throughput sequencing.
Neoplasms
Verapamil inhibits tumor protease production, local invasion and metastasis development in murine carcinoma cells.
Neoplasms
Versatile Functionalization of Poly(methacrylic acid) Brushes with Series of Proteolytically Cleavable Peptides for Highly Sensitive Protease Assay.
Neoplasms
Vertebrate TFPI-2 C-terminal peptides exert therapeutic applications against Gram-negative infections.
Neoplasms
Viability and DNA damage responses of TPPII-deficient Myc- and Ras-transformed fibroblasts.
Neoplasms
Vitamin K-dependent procoagulant in cancer cells: a potential target for the antimetastatic effect of warfarin?
Neoplasms
von Hippel-Lindau tumor suppressor protein stimulation by thrombin involves RhoA activation.
Neoplasms
Vorinostat and hydroxychloroquine improve immunity and inhibit autophagy in metastatic colorectal cancer.
Neoplasms
Vorinostat and sorafenib synergistically kill tumor cells via FLIP suppression and CD95 activation.
Neoplasms
Western blotting and isoform analysis of cathepsin D from normal and malignant human breast cell lines.
Neoplasms
Widespread immunoreactivity for alpha-1-antichymotrypsin in different types of tumors.
Neoplasms
Workshop report from the Division of Cancer Etiology, National Cancer Institute, National Institutes of Health. Protease inhibitors as cancer chemopreventive agents.
Neoplasms
Zebrafish modeling reveals that SPINT1 regulates the aggressiveness of skin cutaneous melanoma and its crosstalk with tumor immune microenvironment.
Neoplasms
Zinc oxide nanoparticles enhance expression of maspin in human breast cancer cells.
Neoplasms
[A review on the role of angiotensin-converting enzyme 2 in children with coronavirus disease 2019].
Neoplasms
[Activity of cathepsin D in the blood serum and urine of patients with cancer of the stomach, pancreas and liver]
Neoplasms
[Anti-metastatic effects of serine protease inhibitors: animal models for analysis]
Neoplasms
[Assessment of the efficacy of cancer procoagulant (CP) activity evaluation in the oncological diagnosis of the urinary system]
Neoplasms
[Association of immune system gene polymorphisms with quantitative features which are pathogenetically important in chronic viral hepatitis]
Neoplasms
[Association of uPA and uPAR expression with invasive behaviors of urinary transitional cell carcinoma]
Neoplasms
[Autocrine-generated matrix metalloproteinases of tumor cells and the cascade network of protease activation mediated by membrane associated urokinase-type plasminogen activator: involvement in the degradation of extracellular matrices]
Neoplasms
[Caspase-2 as an Oncosupressor and Metabolism Regulator: What Life Will Bring over the Long Run?]
Neoplasms
[Change in endogeous hydrogen sulfide in patients with acute pancreatitis and its relationship to coagulation function].
Neoplasms
[Clinical and prognostic significance of tumor-associated proteases in gynecologic oncology]
Neoplasms
[Diagnostic value of determining alpha1 protease inhibitor and alpha2 macroglobulin in the serum of women with malignant and non-malignant ovarian tumors and uterine myomas]
Neoplasms
[Digestion in vitro of basal membrane, bovine lens capsule, by human liver lysosome cathepsins B, H and L and ascitic fluid tumor cathepsin B from ovarian adenocarcinoma]
Neoplasms
[Dipeptidyl peptidase IV (DPP IV, CD 26): a tumor marker in cytologic and histopathologic diagnosis of lesions of the thyroid gland]
Neoplasms
[Effect of anticancer drugs on invasive capacity of human small-cell lung cancer cells in vitro]
Neoplasms
[Effect of moxa-burning heat stimulating Liangmen (ST 21) and Zusanli (ST 36) on proliferation and apoptosis signaling proteins in rats with stress-induced gastric ulcer].
Neoplasms
[Expression of human epidermal growth factor and DNA ploidy pattern in gastric carcinoma]
Neoplasms
[Immunohistochemical characteristics and a degree of differentiation of urinary bladder cancer]
Neoplasms
[Immunomodulatory activity and anti-tumor activity of Oldenlandia diffusa in vitro]
Neoplasms
[In-vivo imaging of tumors with protease activated near-infrared fluorescent probes]
Neoplasms
[Increased complexes between protease and protease inhibitor in the plasma from patients with neoplasm]
Neoplasms
[Inhibitory effect and the mechanism of Astragalus polysaccharide combined with cisplatin on growth of inplanted Lewis lung carcinoma in mice].
Neoplasms
[Inhibitory effects of alpha 1 protease inhibitor on the production of IL-1 and TNF alpha by alveolar macrophages in patients with lung cancer]
Neoplasms
[Mechanism of formation of blocking factors and method of antiblocking immunotherapy in malignant tumors]
Neoplasms
[Mechanism of tumor cell-induced extracellular matrix degradation--inhibition of cell-surface proteolytic activity might have a therapeutic effect on tumor cell invasion and metastasis]
Neoplasms
[Mechanisms of tumor invasion in the laryngeal structure. A study of undecalcified thin sections]
Neoplasms
[Natural history of ovarian adenocarcinomas: from epidemiology to experimentation]
Neoplasms
[Plasminogen activator system and its clinical significance in patients with a malignant disease].
Neoplasms
[Prognostic value of immunohistochemical determination of urokinase plasminogen activator in primary breast cancers]
Neoplasms
[Protease inhibitors as anticancer chemotherapy--experimental and clinical studies]
Neoplasms
[Screening of TACE peptide inhibitors from a phage display random 15-peptide library by recombinant TACE ecotodomain]
Neoplasms
[Signaling pathways regulating the expression of proteases during tumor progression]
Neoplasms
[Significance of urokinase and its inhibitors in the invasiveness and metastasing of malignant tumors].
Neoplasms
[Studies on fibrinolysis and ascites accumulation associated with peritonitis carcinomatosa--effects of protease inhibitors (PI) on MM2 ascites tumor growth, ascites accumulation and fibrinolysis]
Neoplasms
[The clinical prospects for the study of the plasminogen activation system in breast cancer]
Neoplasms
[The role of cathepsins and the plasminogen activator/inhibitor system in colorectal cancer]
Neoplasms
[The role of protease activities in the local infiltrative mechanism of cutaneous malignant tumors]
Neoplasms
[The role of the system of proteolytic enzymes and their inhibitors in the pathogenesis of ovarian tumors in Wistar rats and the possibilities for correcting the disorders detected]
Neoplasms
[The urokinase-type plasminogen activator system and its role in tumor progression].
Neoplasms, Germ Cell and Embryonal
Epigenetic silencing of the putative tumor suppressor gene testisin in testicular germ cell tumors.
Neoplasms, Germ Cell and Embryonal
Placental-like alkaline phosphatase reactivity in human tumors: an immunohistochemical study of 520 cases.
Neoplasms, Glandular and Epithelial
Fibroblast activation protein ? in tumor microenvironment: Recent progression and implications (Review).
Neoplastic Cells, Circulating
Functional profiling of circulating tumor cells with an integrated vortex capture and single-cell protease activity assay.
Nephritis
Antiserum against tumor necrosis factor-alpha and a protease inhibitor reduce immune glomerular injury.
Nephritis
Collagenase activity of rat kidney with glomerulonephritis is inhibited by erythromycin.
Nephritis
Corin: an ANP protease that may regulate sodium reabsorption in nephrotic syndrome.
Nephritis
Effect of antiproteolytic drugs: epsilon-aminocaproic acid (EACA) and aprotinin on experimental anti-GBM nephritis.
Nephritis
Increased mRNA expression encoding for medullasin in peripheral blood mononuclear cells from patients with IgA nephropathy.
Nephritis
Renal effects of non-tenofovir antiretroviral therapy in patients living with HIV.
Nephritis
Urine proteome scans uncover total urinary protease, prostaglandin D synthase, serum amyloid P, and superoxide dismutase as potential markers of lupus nephritis.
Nephritis, Hereditary
Antigen retrieval with protease digestion applied in immunohistochemical diagnosis of Alport syndrome.
Nephritis, Interstitial
Acute interstitial nephritis associated with atazanavir, a new protease inhibitor.
Nephritis, Interstitial
Pharmacotherapy Considerations in CKD Patients With COVID-19, A Narrative Review.
Nephritis, Interstitial
SerpinB9 expression in human renal tubular epithelial cells is induced by triggering of the viral dsRNA sensors TLR3, MDA5 and RIG-I.
Nephrolithiasis
Endourological management of a rare radiopaque ritonavir-composed urinary calculus.
Nephrolithiasis
Focal mycobacterial lymphadenitis following initiation of protease-inhibitor therapy in patients with advanced HIV-1 disease.
Nephrolithiasis
Indinavir crystalluria: identification of patients at increased risk of developing nephrotoxicity.
Nephrolithiasis
Indinavir-induced nephrolithiasis three and one-half years after cessation of indinavir therapy.
Nephrolithiasis
Nephrolithiasis and renal failure among patients exposed to atazanavir, other PIs and PI-free regimens.
Nephrolithiasis
Pharmacotherapy Considerations in CKD Patients With COVID-19, A Narrative Review.
Nephrolithiasis
Prevalence of nephrolithiasis in human immunodeficiency virus infected patients on the highly active antiretroviral therapy.
Nephrolithiasis
Renal effects of non-tenofovir antiretroviral therapy in patients living with HIV.
Nephrolithiasis
Ritonavir-boosted darunavir is rarely associated with nephrolithiasis compared with ritonavir-boosted atazanavir in HIV-infected patients.
Nephrolithiasis
[Crystalluria and nephrolithiasis during therapy with the protease inhibitor indinavir]
Nephrosis
Urine protease and antiprotease activity in experimental aminonucleoside nephrotoxicity.
Nephrosis, Lipoid
Minimal change-like glomerular alterations induced by a human plasma factor.
Nephrosis, Lipoid
Reduced Lon protease 1 expression in podocytes contributes to the pathogenesis of podocytopathy.
Nephrotic Syndrome
Aprotinin prevents proteolytic epithelial sodium channel (ENaC) activation and volume retention in nephrotic syndrome.
Nephrotic Syndrome
Corin: an ANP protease that may regulate sodium reabsorption in nephrotic syndrome.
Nephrotic Syndrome
Effect of camostat mesilate on urinary protein excretion in three patients with advanced diabetic nephropathy.
Nephrotic Syndrome
Effect of proteinase inhibitor camostat mesilate on nephrotic syndrome with diabetic nephropathy.
Nephrotic Syndrome
Experimental nephrotic syndrome leads to proteolytic activation of the epithelial Na+ channel in the mouse kidney.
Nephrotic Syndrome
Plasma alpha 2 macroglobulin is increased in nephrotic patients as a result of increased synthesis alone.
Nephrotic Syndrome
Plasma levels and urinary excretion of fibrinolytic and protease inhibitory proteins in nephrotic syndrome.
Nephrotic Syndrome
Plasma levels of the von Willebrand factor-cleaving protease in physiological and pathological conditions in children.
Nephrotic Syndrome
Protease inhibitor therapy for HIV infection: the effect on HIV-associated nephrotic syndrome.
Nephrotic Syndrome
Proteasuria in nephrotic syndrome-quantification and proteomic profiling.
Nephrotic Syndrome
Upregulation of the immunoproteasome in peripheral blood mononuclear cells of patients with IgA nephropathy.
Nephrotic Syndrome
[Favorable effects of epsilon-aminocaproic acid on the children with nephrotic syndrome and Schonlein-Henoch syndrome treated with corticosteroids]
Nervous System Diseases
Comparison of human glutamate carboxypeptidases II and III reveals their divergent substrate specificities.
Nervous System Diseases
Crystal structure and autoactivation pathway of the precursor form of human tripeptidyl-peptidase 1, the enzyme deficient in late infantile ceroid lipofuscinosis.
Nervous System Diseases
Gelatinase in the cerebrospinal fluid of patients with multiple sclerosis and other inflammatory neurological disorders.
Nervous System Diseases
Occurrence of reduced alpha 2-macroglobulin and lowered protease inhibiting capacity in plasma of amyotrophic lateral sclerosis patients.
Nervous System Diseases
Prion protein gene variability in Spanish goats. Inference through susceptibility to classical scrapie strains and pathogenic distribution of peripheral PrP(sc.).
Nervous System Neoplasms
Treatment with field bean protease inhibitor can effectively repress ethylnitrosourea (ENU)-induced neoplasms of the nervous system in Sprague-Dawley rats.
Netherton Syndrome
A case of netherton syndrome: successful treatment with omalizumab and pulse prednisolone and its effects on cytokines and immunoglobulin levels.
Netherton Syndrome
A heterozygous null mutation combined with the G1258A polymorphism of SPINK5 causes impaired LEKTI function and abnormal expression of skin barrier proteins.
Netherton Syndrome
A Potent and Selective Kallikrein-5 Inhibitor Delivers High Pharmacological Activity in Skin from Patients with Netherton Syndrome.
Netherton Syndrome
A synonymous mutation in SPINK5 exon 11 causes Netherton syndrome by altering exonic splicing regulatory elements.
Netherton Syndrome
Association between polymorphisms in the SPINK5 gene and atopic dermatitis in the Japanese.
Netherton Syndrome
Cathelicidin represents a new target for manipulation of skin inflammation in Netherton syndrome.
Netherton Syndrome
Characterization and expression analysis of the Spink5 gene, the mouse ortholog of the defective gene in Netherton syndrome.
Netherton Syndrome
Clinical and molecular implications of structural changes to desmosomes and corneodesmosomes.
Netherton Syndrome
Clinical Expression and New SPINK5 Splicing Defects in Netherton Syndrome: Unmasking a Frequent Founder Synonymous Mutation and Unconventional Intronic Mutations.
Netherton Syndrome
Corneodesmosomal cadherins are preferential targets of stratum corneum trypsin- and chymotrypsin-like hyperactivity in Netherton syndrome.
Netherton Syndrome
Correlation between SPINK5 Gene Mutations and Clinical Manifestations in Netherton Syndrome Patients.
Netherton Syndrome
Elastase 2 is expressed in human and mouse epidermis and impairs skin barrier function in Netherton syndrome through filaggrin and lipid misprocessing.
Netherton Syndrome
Elevated stratum corneum hydrolytic activity in Netherton syndrome suggests an inhibitory regulation of desquamation by SPINK5-derived peptides.
Netherton Syndrome
Epidermal barrier abnormalities in exfoliative ichthyosis with a novel homozygous loss-of-function mutation in CSTA.
Netherton Syndrome
Generation of a quenched phosphonate activity-based probe for labelling the active KLK7 protease.
Netherton Syndrome
Generation of recombinant antibodies against human tissue kallikrein 7 to treat skin diseases.
Netherton Syndrome
Human involucrin promoter mediates repression-resistant and compartment-specific LEKTI expression.
Netherton Syndrome
Identification by in silico and in vitro screenings of small organic molecules acting as reversible inhibitors of kallikreins.
Netherton Syndrome
Identification of lympho-epithelial Kazal-type inhibitor 2 in human skin as a kallikrein-related peptidase 5-specific protease inhibitor.
Netherton Syndrome
Intercellular Skin Barrier Lipid Composition and Organization in Netherton Syndrome Patients.
Netherton Syndrome
Interplay of Staphylococcal and Host Proteases Promotes Skin Barrier Disruption in Netherton Syndrome.
Netherton Syndrome
Kallikrein 5 induces atopic dermatitis-like lesions through PAR2-mediated thymic stromal lymphopoietin expression in Netherton syndrome.
Netherton Syndrome
KLK5 and KLK7 Ablation Fully Rescues Lethality of Netherton Syndrome-Like Phenotype.
Netherton Syndrome
LEKTI proteolytic processing in human primary keratinocytes, tissue distribution and defective expression in Netherton syndrome.
Netherton Syndrome
Matriptase initiates activation of epidermal pro-kallikrein and disease onset in a mouse model of Netherton syndrome.
Netherton Syndrome
Mutations in SPINK5, encoding a serine protease inhibitor, cause Netherton syndrome.
Netherton Syndrome
Netherton syndrome previously misdiagnosed as hyper IgE syndrome caused by a probable mutation in SPINK5 C.
Netherton Syndrome
Netherton syndrome subtypes share IL-17/IL-36 signature with distinct IFN-? and allergic responses.
Netherton Syndrome
Netherton syndrome: disease expression and spectrum of SPINK5 mutations in 21 families.
Netherton Syndrome
Netherton syndrome: skin inflammation and allergy by loss of protease inhibition.
Netherton Syndrome
Phase I study protocol for ex vivo lentiviral gene therapy for the inherited skin disease, Netherton syndrome.
Netherton Syndrome
Phase I study protocol for ex-vivo lentiviral gene therapy for the inherited skin disease, Netherton Syndrome.
Netherton Syndrome
Serine protease activity and residual LEKTI expression determine phenotype in Netherton syndrome.
Netherton Syndrome
Skin barrier lipid enzyme activity in Netherton patients is associated with protease activity and ceramide abnormalities.
Netherton Syndrome
SPINK5 knockdown in organotypic human skin culture as a model system for Netherton syndrome: effect of genetic inhibition of serine proteases kallikrein 5 and kallikrein 7.
Netherton Syndrome
SPINK5, the defective gene in netherton syndrome, encodes multiple LEKTI isoforms derived from alternative pre-mRNA processing.
Netherton Syndrome
Spink5-deficient mice mimic Netherton syndrome through degradation of desmoglein 1 by epidermal protease hyperactivity.
Netherton Syndrome
Therapeutic Implications of a Barrier-Based Pathogenesis of Atopic Dermatitis.
Netherton Syndrome
Transgenic kallikrein 5 mice reproduce major cutaneous and systemic hallmarks of Netherton syndrome.
Neural Tube Defects
Analysis of the effects of Streptomyces hyaluronidase on formation of the neural tube.
Neural Tube Defects
Reduced Prostasin (CAP1/PRSS8) Activity Eliminates HAI-1 and HAI-2 Deficiency-Associated Developmental Defects by Preventing Matriptase Activation.
Neuralgia
Cav3.2 overexpression in L4 dorsal root ganglion neurons after L5 spinal nerve cutting involves Egr-1, USP5 and HMGB1 in rats: An emerging signaling pathway for neuropathic pain.
Neuralgia
Cytokine expressions of spinal cord injury treated by neurotropin and nafamostat mesylate.
Neuralgia
Effect of recombinant adenovirus coding for endomorphin-2 on neuropathic pain in rats.
Neuralgia
Nerve injury evoked loss of latexin expression in spinal cord neurons contributes to the development of neuropathic pain.
Neuralgia
Neuropathic pain in HIV patients receiving ART without stavudine in an Indonesia Referral Hospital.
Neuralgia
Protease activated receptor 4 status of mast cells in post infectious irritable bowel syndrome.
Neuralgia
The serine protease inhibitor SerpinA3N attenuates neuropathic pain by inhibiting T cell-derived leukocyte elastase.
Neuralgia
Therapeutic potential for leukocyte elastase in chronic pain states harboring a neuropathic component.
Neurilemmoma
Tight association of loss of merlin expression with loss of heterozygosity at chromosome 22q in sporadic meningiomas.
Neuritis, Autoimmune, Experimental
The use of protease inhibitors in experimental allergic neuritis.
Neuroblastoma
A novel combination therapy targeting ubiquitin-specific protease 5 in MYCN-driven neuroblastoma.
Neuroblastoma
Abnormal properties of prion protein with insertional mutations in different cell types.
Neuroblastoma
Acyl peptide hydrolase, a serine proteinase isolated from conditioned medium of neuroblastoma cells, degrades the amyloid-beta peptide.
Neuroblastoma
Addition of protease inhibitors to culture medium of neuroblastoma cells induces both neurite outgrowth and phosphorylation of microtubule-associated protein MAP-1B.
Neuroblastoma
Alterations of extracellular calcium elicit selective modes of cell death and protease activation in SH-SY5Y human neuroblastoma cells.
Neuroblastoma
Amyloid beta-protein is degraded by cellular angiotensin-converting enzyme (ACE) and elevated by an ACE inhibitor.
Neuroblastoma
Botulinum neurotoxin type C protease induces apoptosis in differentiated human neuroblastoma cells.
Neuroblastoma
Ca(2+)-induced inhibition of apoptosis in human SH-SY5Y neuroblastoma cells: degradation of apoptotic protease activating factor-1 (APAF-1).
Neuroblastoma
Caspase-8 association with the focal adhesion complex promotes tumor cell migration and metastasis.
Neuroblastoma
Characterization of an insulin-like growth factor binding protein-5 protease produced by rat articular chondrocytes and a neuroblastoma cell line.
Neuroblastoma
Characterization of CPP32-like protease activity following apoptotic challenge in SH-SY5Y neuroblastoma cells.
Neuroblastoma
Curcumin binds to the alpha-helical intermediate and to the amyloid form of prion protein - a new mechanism for the inhibition of PrP(Sc) accumulation.
Neuroblastoma
DE-71-induced apoptosis involving intracellular calcium and the Bax-mitochondria-caspase protease pathway in human neuroblastoma cells in vitro.
Neuroblastoma
Degradation of dynorphin-(1-13) and dynorphin-(1-17) by the neuroblastoma cell membrane. Evidence for the involvement of a cysteine protease.
Neuroblastoma
Enhancement of neurite outgrowth from central nervous system neurons in primary culture by thrombin inhibitors.
Neuroblastoma
Evidence that neutral sphingomyelinase of cultured murine neuroblastoma cells is oriented externally on the plasma membrane.
Neuroblastoma
Fumonisin B1-induced apoptosis in neuroblastoma, glioblastoma and hypothalamic cell lines.
Neuroblastoma
Functional sites of glia-derived nexin (GDN): importance of the site reacting with the protease.
Neuroblastoma
Glia-derived nexin potentiates neurite extension in hippocampal pyramidal cells in vitro.
Neuroblastoma
Heparan sulfate proteoglycans in the substratum adhesion sites of human neuroblastoma cells: modulation of affinity binding to fibronectin.
Neuroblastoma
Honokiol traverses the blood-brain barrier and induces apoptosis of neuroblastoma cells via an intrinsic bax-mitochondrion-cytochrome c-caspase protease pathway.
Neuroblastoma
Immunoreactivity, ultrastructural localization, and transcript expression of prostate-specific antigen in human neuroblastoma cell lines.
Neuroblastoma
Inhibition of protease activity can lead to neurite extension in neuroblastoma cells.
Neuroblastoma
Inhibition of Ubiquitin-Specific Protease 14 Suppresses Cell Proliferation and Synergizes with Chemotherapeutic Agents in Neuroblastoma.
Neuroblastoma
Interleukin-1 beta converting enzyme (ICE) is preferentially expressed in neuroblastomas with favourable prognosis.
Neuroblastoma
Involvement of puromycin-sensitive aminopeptidase in proteolysis of tau protein in cultured cells, and attenuated proteolysis of frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17) mutant tau.
Neuroblastoma
Lysosomal proteases as potential targets for the induction of apoptotic cell death in human neuroblastomas.
Neuroblastoma
Mechanisms of uptake of gallium by human neuroblastoma cells and effects of gallium and aluminum on cell growth, lysosomal protease, and choline acetyl transferase activity.
Neuroblastoma
Modification of opioid receptor activity by acid phosphatase in neuroblastoma x glioma NG108-15 hybrid cells.
Neuroblastoma
Mutant prion protein acquires resistance to protease in mouse neuroblastoma cells.
Neuroblastoma
Neurite outgrowth activity of protease nexin-1 on neuroblastoma cells requires thrombin inhibition.
Neuroblastoma
Neuroprotective effects of Mycoplasma hyorhinis against amyloid-?-peptide toxicity in SH-SY5Y human neuroblastoma cells are mediated by calpastatin upregulation in the mycoplasma-infected cells.
Neuroblastoma
NF-?B Regulates Caspase-4 Expression and Sensitizes Neuroblastoma Cells to Fas-Induced Apoptosis.
Neuroblastoma
NMDA and HIV-1 coat protein, GP120, produce necrotic but not apoptotic cell death in human CHP100 neuroblastoma cultures via a mechanism involving calpain.
Neuroblastoma
Novel synthetic lipopeptides derived from Mycoplasma hyorhinis upregulate calpastatin in SH-SY5Y neuroblastoma cells and induce a neuroprotective effect against amyloid-?-peptide toxicity.
Neuroblastoma
Plasma membrane targeting of SNAP-25 increases its local concentration and is necessary for SNARE complex formation and regulated exocytosis.
Neuroblastoma
Plasminogen activators and inhibitors in the neuromuscular system: III. The serpin protease nexin I is synthesized by muscle and localized at neuromuscular synapses.
Neuroblastoma
Potent growth-suppressive activity of a serine protease inhibitor, ONO-3403, toward malignant human neuroblastoma cell lines.
Neuroblastoma
Protease Omi cleaving Hax-1 protein contributes to OGD/R-induced mitochondrial damage in neuroblastoma N2a cells and cerebral injury in MCAO mice.
Neuroblastoma
Protease Omi facilitates neurite outgrowth in mouse neuroblastoma N2a cells by cleaving transcription factor E2F1.
Neuroblastoma
Protease sensitivity and nuclease resistance of the scrapie agent propagated in vitro in neuroblastoma cells.
Neuroblastoma
Proteasome or calpain inhibition does not alter cellular tau levels in neuroblastoma cells or primary neurons.
Neuroblastoma
Proteolytic regulation of neurite outgrowth from neuroblastoma cells by thrombin and protease nexin-1.
Neuroblastoma
Regulation of neurite outgrowth through protein kinase C and protease nexin-1 in neuroblastoma cell.
Neuroblastoma
Regulation of neuronal migration and neuritogenesis by distinct surface proteases. Relative contribution of plasmin and a thrombin-like protease.
Neuroblastoma
Screening for genetic abnormalities involved in ovarian carcinogenesis using retroviral expression libraries.
Neuroblastoma
Sequential effects of astroglial-derived factors on neurite outgrowth: initiation by protease inhibitors and potentiation by extracellular matrix components.
Neuroblastoma
Stimulation of beta-amyloid precursor protein alpha-processing by phorbol ester involves calcium and calpain activation.
Neuroblastoma
Structure-function studies on inhibitory activity of Bungarus multicinctus protease inhibitor-like protein on matrix metalloprotease-2, and invasion and migration of human neuroblastoma SK-N-SH cells.
Neuroblastoma
Suppression of neuroblastoma growth by dipeptidyl peptidase IV: relevance of chemokine regulation and caspase activation.
Neuroblastoma
Symplocamide A, a potent cytotoxin and chymotrypsin inhibitor from the marine Cyanobacterium Symploca sp.
Neuroblastoma
Temporal changes in chromatin, intracellular calcium, and poly(ADP-ribose) polymerase during Sindbis virus-induced apoptosis of neuroblastoma cells.
Neuroblastoma
The effects of serine protease inhibitors on morphological differentiation of murine neuroblastoma cells (NB15).
Neuroblastoma
The membrane topological analysis of 3?-hydroxysteroid-Delta24 reductase (DHCR24) on endoplasmic reticulum.
Neuroblastoma
Thiol-dependent membrane-bound metallo-endopeptidase functioning in degradation of luteinizing hormone-releasing hormone in neuroblastoma cells and rat brain synaptic membrane. Isolation and characterization.
Neuroblastoma
Transient neuritogenesis in NB2a/d1 neuroblastoma cells induced by glial-derived protease inhibitors.
Neuroblastoma
Ubiquitin-specific protease 22 is associated with poor prognosis in neuroblastoma.
Neurocysticercosis
A membrane-associated metalloprotease of Taenia solium metacestode structurally related to the FACE-1/Ste24p protease family.
Neurodegenerative Diseases
3K3A-activated protein C blocks amyloidogenic BACE1 pathway and improves functional outcome in mice.
Neurodegenerative Diseases
A mouse model of classical late-infantile neuronal ceroid lipofuscinosis based on targeted disruption of the CLN2 gene results in a loss of tripeptidyl-peptidase I activity and progressive neurodegeneration.
Neurodegenerative Diseases
A mutation in the serine protease TMPRSS4 in a novel pediatric neurodegenerative disorder.
Neurodegenerative Diseases
A Novel 2-DE-Based Proteomic Analysis to Identify Multiple Substrates for Specific Protease in Neuronal Cells.
Neurodegenerative Diseases
Age-associated neurodegeneration and oxidative damage to lipids, proteins and DNA.
Neurodegenerative Diseases
Allosteric Regulation of Serine Protease HtrA2 through Novel Non-Canonical Substrate Binding Pocket.
Neurodegenerative Diseases
Altered regulation of phosphatidylinositol 3-kinase signaling in cathepsin D-deficient brain.
Neurodegenerative Diseases
Analysis of catalytic properties of tripeptidyl peptidase I (TTP-I), a serine carboxyl lysosomal protease, and its detection in tissue extracts using selective FRET peptide substrate.
Neurodegenerative Diseases
Archaeal proteasomes effectively degrade aggregation-prone proteins and reduce cellular toxicities in mammalian cells.
Neurodegenerative Diseases
Calcium-activated calpain-2 is a mediator of beta cell dysfunction and apoptosis in type 2 diabetes.
Neurodegenerative Diseases
Calpastatin overexpression reduces oxidative stress-induced mitochondrial impairment and cell death in human neuroblastoma SH-SY5Y cells by decreasing calpain and calcineurin activation, induction of mitochondrial fission and destruction of mitochondrial fusion.
Neurodegenerative Diseases
Chronic Enzyme Replacement to the Brain of a Late Infantile Neuronal Ceroid Lipofuscinosis Mouse Has Differential Effects on Phenotypes of Disease.
Neurodegenerative Diseases
Constitutive ablation of caspase-6 reduces the inflammatory response and behavioural changes caused by peripheral pro-inflammatory stimuli.
Neurodegenerative Diseases
Contribution of a metal-peroxide adduct to neurodegeneration is due to its oxidative protease activity.
Neurodegenerative Diseases
Cyclotides Isolated From Violet Plants of Cameroon Are Inhibitors of Human Prolyl Oligopeptidase.
Neurodegenerative Diseases
Cytoskeletal changes in rat cortical neurons induced by long-term intraventricular infusion of leupeptin.
Neurodegenerative Diseases
Detection of Protein Uptake in In Vitro Cultured Astrocytes Exemplified by the Uptake of the Serine Protease, Tissue Plasminogen Activator.
Neurodegenerative Diseases
Determination of the substrate specificity of tripeptidyl-peptidase I using combinatorial peptide libraries and development of improved fluorogenic substrates.
Neurodegenerative Diseases
Dipeptidyl-peptidase I does not functionally compensate for the loss of tripeptidyl-peptidase I in the neurodegenerative disease late-infantile neuronal ceroid lipofuscinosis.
Neurodegenerative Diseases
Dissecting the role of interprotomer cooperativity in the activation of oligomeric high-temperature requirement A2 protein.
Neurodegenerative Diseases
Effect of neurotoxic metal ions in vitro on proteolytic enzyme activities in human cerebral cortex.
Neurodegenerative Diseases
Effects of porcine brain hydrolysate on impairment of cognitive learning ability in amyloid ?(1-40) -infused rats.
Neurodegenerative Diseases
G392E neuroserpin causing the dementia FENIB is secreted from cells but is not synaptotoxic.
Neurodegenerative Diseases
Gel-based protease proteomics for identifying the novel calpain substrates in dopaminergic neuronal cell.
Neurodegenerative Diseases
Glial fibrillary acidic protein is elevated in the lysosomal storage disease classical late-infantile neuronal ceroid lipofuscinosis but is not a component of the storage material.
Neurodegenerative Diseases
Idebenone and resveratrol extend lifespan and improve motor function of HtrA2 knockout mice.
Neurodegenerative Diseases
Identification of potential mitochondrial CLPXP protease interactors and substrates suggests its central role in energy metabolism.
Neurodegenerative Diseases
Immunocytochemical co-localization of the proteasome in ubiquitinated structures in neurodegenerative diseases and the elderly.
Neurodegenerative Diseases
Inducible transgenic expression of tripeptidyl peptidase 1 in a mouse model of late-infantile neuronal ceroid lipofuscinosis.
Neurodegenerative Diseases
Inhibiting USP14 ameliorates inflammatory responses in trophoblast cells by suppressing MAPK/NF-?B signaling.
Neurodegenerative Diseases
Intra- and intersubunit changes accompanying thermal activation of the HtrA2(Omi) protease homotrimer.
Neurodegenerative Diseases
Intraventricular Enzyme Replacement Improves Disease Phenotypes in a Mouse Model of Late Infantile Neuronal Ceroid Lipofuscinosis.
Neurodegenerative Diseases
Intraventricular enzyme replacement improves disease phenotypes in a mouse model of late infantile neuronal ceroid lipofuscinosis.
Neurodegenerative Diseases
Mitochondrial protein quality control systems in aging and disease.
Neurodegenerative Diseases
MMP-1 overexpression selectively alters inhibition in D1 spiny projection neurons in the mouse nucleus accumbens core.
Neurodegenerative Diseases
Monitoring Proteolytic Activity in Real Time: A New World of Opportunities for Biosensors.
Neurodegenerative Diseases
MSP, a trypsin-like serine protease, is abundantly expressed in the human nervous system.
Neurodegenerative Diseases
Natural Biomolecules and Protein Aggregation: Emerging Strategies against Amyloidogenesis.
Neurodegenerative Diseases
Neuroproteases in peptide neurotransmission and neurodegenerative diseases: applications to drug discovery research.
Neurodegenerative Diseases
One round of SELEX for the generation of DNA aptamers directed against KLK6.
Neurodegenerative Diseases
Peptidase activities of the 20/26S proteasome and a novel protease in human brain.
Neurodegenerative Diseases
Prion protein misfolding affects calcium homeostasis and sensitizes cells to endoplasmic reticulum stress.
Neurodegenerative Diseases
Prolyl oligopeptidase inhibition activates autophagy via protein phosphatase 2A.
Neurodegenerative Diseases
Protease inhibitors and their peptidomimetic derivatives as potential drugs.
Neurodegenerative Diseases
Protease pathways in peptide neurotransmission and neurodegenerative diseases.
Neurodegenerative Diseases
Protein Hydrolysate of Silkworm Pupa Prevents Memory Impairment Induced by Oxidative Stress in Scopolamine-Induced Mice via Modulating the Cholinergic Nervous System and Antioxidant Defense System.
Neurodegenerative Diseases
Protein markers for the differential diagnosis of vascular dementia and Alzheimer's disease.
Neurodegenerative Diseases
Purkinje neuron Ca2+ influx reduction rescues ataxia in SCA28 model.
Neurodegenerative Diseases
Reference intervals and biological variation for kallikrein 6: influence of age and renal failure.
Neurodegenerative Diseases
Residue-specific mobility changes in soluble oligomers of the prion protein define regions involved in aggregation.
Neurodegenerative Diseases
Similarities and differences in the biogenesis, processing and lysosomal targeting between zebrafish and human pro-Cathepsin D: functional implications.
Neurodegenerative Diseases
Specific substrate for CLN2 protease/tripeptidyl-peptidase I assay.
Neurodegenerative Diseases
Stress Conditions Increase Vimentin Cleavage by Omi/HtrA2 Protease in Human Primary Neurons and Differentiated Neuroblastoma Cells.
Neurodegenerative Diseases
SUMO-specific protease 2 (SENP2) suppresses keratinocyte migration by targeting NDR1 for de-SUMOylation.
Neurodegenerative Diseases
Synonymous variants in HTRA1 implicated in AMD susceptibility impair its capacity to regulate TGF-? signaling.
Neurodegenerative Diseases
Targeted Covalent Inhibition of Prolyl Oligopeptidase (POP): Discovery of Sulfonylfluoride Peptidomimetics.
Neurodegenerative Diseases
The calpain inhibitor MDL 28170 prevents inflammation-induced neurofilament light chain breakdown in the spinal cord and reduces thermal hyperalgesia.
Neurodegenerative Diseases
The compound (3-{5-[(2,5-dimethoxyphenyl)amino]-1,3,4-thiadiazolidin-2-yl}-5,8-methoxy-2H-chromen-2-one) inhibits the prion protein conversion from PrP
Neurodegenerative Diseases
The regulatory mechanism of the caspase 6 pro-domain revealed by crystal structure and biochemical assays.
Neurodegenerative Diseases
Two-dimensional mapping of three phenotype-associated isoforms of the prion protein in sporadic Creutzfeldt-Jakob disease.
Neurodegenerative Diseases
Ubiquitin C-terminal hydrolase-l1 activity induces polyubiquitin accumulation in podocytes and increases proteinuria in rat membranous nephropathy.
Neurodegenerative Diseases
Ubiquitin-specific protease 14 is a new therapeutic target for the treatment of diseases.
Neurodegenerative Diseases
Unique Structural Features of the Mitochondrial AAA+ Protease AFG3L2 Reveal the Molecular Basis for Activity in Health and Disease.
Neurodermatitis
The serine protease inhibitor of Kazal-type 9 (SPINK9) is expressed in lichen simplex chronicus, actinic keratosis and squamous cell carcinoma.
Neurodermatitis
[Establishment of a SD rat model of vulvar lichen simplex chronicus and detection of the expression of protease activated receptor 2].
Neuroendocrine Tumors
Distinct functions of macrophage-derived and cancer cell-derived cathepsin Z combine to promote tumor malignancy via interactions with the extracellular matrix.
Neuroendocrine Tumors
Serine protease inhibitor 8 is a novel immunohistochemical marker for neuroendocrine tumors of the pancreas.
Neurofibromatoses
A universal expression-purification system based on the coiled-coil interaction of myosin heavy chain.
Neurofibromatosis 1
A universal expression-purification system based on the coiled-coil interaction of myosin heavy chain.
Neurogenic Inflammation
The transient receptor potential vanilloid 4 (TRPV4) ion channel mediates protease activated receptor 1 (PAR1)-induced vascular hyperpermeability.
Neuroinflammatory Diseases
A serine protease inhibitor suppresses autoimmune neuroinflammation by activating the STING/IFN-? axis in macrophages.
Neuroinflammatory Diseases
Activation of the amyloid cascade by intracerebroventricular injection of the protease inhibitor phosphoramidon.
Neuroinflammatory Diseases
Cathepsin C aggravates neuroinflammation via promoting production of CCL2 and CXCL2 in glial cells and neurons in a cryogenic brain lesion.
Neuroinflammatory Diseases
Cytoprotective protein C pathways and implications for stroke and neurological disorders.
Neuroinflammatory Diseases
Differential expression of 14 genes in amyotrophic lateral sclerosis spinal cord detected using gridded cDNA arrays.
Neuroinflammatory Diseases
Inhibition of PAR-2 Attenuates Neuroinflammation and Improves Short-Term Neurocognitive Functions via ERK1/2 Signaling Following Asphyxia-Induced Cardiac Arrest in Rats.
Neuroinflammatory Diseases
Ligation of the jugular veins does not result in brain inflammation or demyelination in mice.
Neuroinflammatory Diseases
Natural haemozoin modulates matrix metalloproteinases and induces morphological changes in human microvascular endothelium.
Neuroinflammatory Diseases
Regulation of ubiquitin-specific processing protease 8 suppresses neuroinflammation.
Neuroinflammatory Diseases
Structural Insights into the Unique Activation Mechanisms of a Non-classical Calpain and Its Disease-Causing Variants.
Neuroinflammatory Diseases
Synergy between plasminogen activator inhibitor-1, ?-synuclein, and neuroinflammation in Parkinson's disease.
Neuroinflammatory Diseases
Targeting Neurological Manifestations of Coronaviruses by Candidate Phytochemicals: A Mechanistic Approach.
Neuroinflammatory Diseases
The Protease Omi Cleaves the Mitogen-Activated Protein Kinase Kinase MEK1 to Inhibit Microglial Activation.
Neuroinflammatory Diseases
Upregulation of Cysteine Protease Cathepsin X in the 6-Hydroxydopamine Model of Parkinson's Disease.
Neuroinflammatory Diseases
USP8 protects against lipopolysaccharide-induced cognitive and motor deficits by modulating microglia phenotypes through TLR4/MyD88/NF-?B signaling pathway in mice.
Neurologic Manifestations
Epidural spinal lipomatosis with acute onset of paraplegia in an HIV-positive patient treated with corticosteroids and protease inhibitor: case report.
Neurologic Manifestations
[Paediatric case report of an acquired autoimmune thrombotic thrombocytopenic purpura]
Neuromuscular Diseases
Expression of beta-amyloid precursor protein gene is developmentally regulated in human muscle fibers in vivo and in vitro.
Neuromuscular Diseases
Genetic background alters the severity and onset of neuromuscular disease caused by the loss of ubiquitin-specific protease 14 (usp14).
Neuronal Ceroid-Lipofuscinoses
A mouse model of classical late-infantile neuronal ceroid lipofuscinosis based on targeted disruption of the CLN2 gene results in a loss of tripeptidyl-peptidase I activity and progressive neurodegeneration.
Neuronal Ceroid-Lipofuscinoses
A replacement of the active-site aspartic acid residue 293 in mouse cathepsin D affects its intracellular stability, processing and transport in HEK-293 cells.
Neuronal Ceroid-Lipofuscinoses
Biochemical characterization of a lysosomal protease deficient in classical late infantile neuronal ceroid lipofuscinosis (LINCL) and development of an enzyme-based assay for diagnosis and exclusion of LINCL in human specimens and animal models.
Neuronal Ceroid-Lipofuscinoses
Chronic Enzyme Replacement to the Brain of a Late Infantile Neuronal Ceroid Lipofuscinosis Mouse Has Differential Effects on Phenotypes of Disease.
Neuronal Ceroid-Lipofuscinoses
Crystal structure and autoactivation pathway of the precursor form of human tripeptidyl-peptidase 1, the enzyme deficient in late infantile ceroid lipofuscinosis.
Neuronal Ceroid-Lipofuscinoses
Determination of the substrate specificity of tripeptidyl-peptidase I using combinatorial peptide libraries and development of improved fluorogenic substrates.
Neuronal Ceroid-Lipofuscinoses
Developmental study of tripeptidyl peptidase I activity in the mouse central nervous system and peripheral organs.
Neuronal Ceroid-Lipofuscinoses
Enzyme-based diagnosis of classical late infantile neuronal ceroid lipofuscinosis: comparison of tripeptidyl peptidase I and pepstatin-insensitive protease assays.
Neuronal Ceroid-Lipofuscinoses
Glial fibrillary acidic protein is elevated in the lysosomal storage disease classical late-infantile neuronal ceroid lipofuscinosis but is not a component of the storage material.
Neuronal Ceroid-Lipofuscinoses
Inducible transgenic expression of tripeptidyl peptidase 1 in a mouse model of late-infantile neuronal ceroid lipofuscinosis.
Neuronal Ceroid-Lipofuscinoses
Intraventricular Enzyme Replacement Improves Disease Phenotypes in a Mouse Model of Late Infantile Neuronal Ceroid Lipofuscinosis.
Neuronal Ceroid-Lipofuscinoses
Intraventricular enzyme replacement improves disease phenotypes in a mouse model of late infantile neuronal ceroid lipofuscinosis.
Neuronal Ceroid-Lipofuscinoses
Large-volume Intrathecal Enzyme Delivery Increases Survival of a Mouse Model of Late Infantile Neuronal Ceroid Lipofuscinosis.
Neuronal Ceroid-Lipofuscinoses
Lysosomal protein thermal stability does not correlate with cellular half-life: global observations and a case study of tripeptidyl-peptidase 1.
Neuronal Ceroid-Lipofuscinoses
Mutational analysis of the defective protease in classic late-infantile neuronal ceroid lipofuscinosis, a neurodegenerative lysosomal storage disorder.
Neuronal Ceroid-Lipofuscinoses
Overexpression in colorectal carcinoma of two lysosomal enzymes, CLN2 and CLN1, involved in neuronal ceroid lipofuscinosis.
Neuronal Ceroid-Lipofuscinoses
Residual levels of tripeptidyl-peptidase I activity dramatically ameliorate disease in late-infantile neuronal ceroid lipofuscinosis.
Neuronal Ceroid-Lipofuscinoses
Specific substrate for CLN2 protease/tripeptidyl-peptidase I assay.
Neuronal Ceroid-Lipofuscinoses
Systemic administration of tripeptidyl peptidase I in a mouse model of late infantile neuronal ceroid lipofuscinosis: effect of glycan modification.
Neuronal Ceroid-Lipofuscinoses
Targeted disruption of the Cln3 gene provides a mouse model for Batten disease. The Batten Mouse Model Consortium [corrected]
Neuronal Ceroid-Lipofuscinoses
The human CLN2 protein/tripeptidyl-peptidase I is a serine protease that autoactivates at acidic pH.
Neuronal Ceroid-Lipofuscinoses
Topographic heterogeneity of amyloid B-protein epitopes in brains with various forms of neuronal ceroid lipofuscinoses suggesting defective processing of amyloid precursor protein.
Neuronal Ceroid-Lipofuscinoses
Viral-mediated delivery of the late-infantile neuronal ceroid lipofuscinosis gene, TPP-I to the mouse central nervous system.
Neutropenia
A lack of secretory leukocyte protease inhibitor (SLPI) causes defects in granulocytic differentiation.
Neutropenia
A novel notch protein, N2N, targeted by neutrophil elastase and implicated in hereditary neutropenia.
Neutropenia
A Potential Mechanism for ADC-Induced Neutropenia: Role of Neutrophils in Their Own Demise.
Neutropenia
Can mutations in ELA2, neutrophil elastase expression or differential cell toxicity explain sulphasalazine-induced agranulocytosis?
Neutropenia
Detrimental clinical interaction between ritonavir-boosted protease inhibitors and vinblastine in HIV-infected patients with Hodgkin's lymphoma.
Neutropenia
High Risk of Infection During Triple Therapy with First-Generation Protease Inhibitors: A Nationwide Cohort Study.
Neutropenia
Kostmann syndrome or infantile genetic agranulocytosis, part two: Understanding the underlying genetic defects in severe congenital neutropenia.
Neutropenia
Lymphoid enhancer factor-1 links two hereditary leukemia syndromes through core-binding factor alpha regulation of ELA2.
Neutropenia
Mutations associated with neutropenia in dogs and humans disrupt intracellular transport of neutrophil elastase.
Neutropenia
Neutrophil and nonneutrophil-mediated injury in intestinal ischemia-reperfusion.
Neutropenia
Risk factors for febrile neutropenia during chemotherapy for HIV-related lymphoma.
Neutropenia
Stage specific gene expression of serpins and their cognate proteases during myeloid differentiation.
Newcastle Disease
Comparison of substrate specificities against the fusion glycoprotein of virulent Newcastle disease virus between a chick embryo fibroblast processing protease and mammalian subtilisin-like proteases.
Newcastle Disease
Differences in hemagglutination inhibition activity against bovine rotavirus and hen Newcastle disease virus based on the subunits in hen egg white ovomucin.
Newcastle Disease
Evolutionary mechanisms involved in the virulence of infectious salmon anaemia virus (ISAV), a piscine orthomyxovirus.
Newcastle Disease
Mutational changes of the protease susceptibility of glycoprotein F of Newcastle disease virus: effects on pathogenicity.
Newcastle Disease
Proteins of Newcastle disease virus. A comparison by partial protease digestion among the strains of different pathogenicity.
Newcastle Disease
Serum protease inhibitor abrogation of Newcastle disease virus enhancement of cytolysis by recombinant tumor necrosis factors alpha and beta.
Newcastle Disease
Structure of the major oligosaccharides in the fusion glycoprotein of Newcastle disease virus.
Newcastle Disease
The spread of a pathogenic and an apathogenic strain of Newcastle disease virus in the chick embryo as depending on the protease sensitivity of the virus glycoproteins.
Non-alcoholic Fatty Liver Disease
Coagulation-driven hepatic fibrosis requires protease activated receptor-1 (PAR-1) in a mouse model of TCDD-elicited steatohepatitis.
Non-alcoholic Fatty Liver Disease
Common SPINK-1 mutations do not predispose to the development of non-alcoholic fatty liver disease.
Non-alcoholic Fatty Liver Disease
Improvement in liver steatosis after the switch from a ritonavir-boosted protease inhibitor to raltegravir in HIV-infected patients with non-alcoholic fatty liver disease.
Non-alcoholic Fatty Liver Disease
Is it appropriate to study blood ghrelin and obestatin in non-alcoholic fatty liver disease (NAFLD) without using protease inhibitors?
Non-alcoholic Fatty Liver Disease
Liver Fat, Adipose Tissue, and Body Composition Changes After Switching from a Protease Inhibitor or Efavirenz to Raltegravir.
Non-alcoholic Fatty Liver Disease
Network pharmacology analysis of Chaihu Lizhong Tang treating non-alcoholic fatty liver disease.
Non-alcoholic Fatty Liver Disease
Plasma cathepsin d levels: a novel tool to predict pediatric hepatic inflammation.
Non-alcoholic Fatty Liver Disease
To what extent is it right to measure serum vaspin, obestatin, and apelin-36 levels without a protease inhibitor in nonalcoholic fatty liver disease?
Non-alcoholic Fatty Liver Disease
Ubiquitin-specific protease 4 is an endogenous negative regulator of metabolic dysfunctions in nonalcoholic fatty liver disease.
Non-alcoholic Fatty Liver Disease
USP18 protects against hepatic steatosis and insulin resistance via its DUB activity.
Non-ST Elevated Myocardial Infarction
Mast cell derived carboxypeptidase A3 is decreased among patients with advanced coronary artery disease.
Obesity
A Non-Perturbative Molecular Grafting Strategy for Stable and Potent Therapeutic Peptide Ligands.
Obesity
A novel adipocytokine, visceral adipose tissue-derived serine protease inhibitor (vaspin), and obesity.
Obesity
Assessment of alpha1-antitrypsin and alpha2-macroglobulin levels in obese patients.
Obesity
Bace1-dependent amyloid processing regulates hypothalamic leptin sensitivity in obese mice.
Obesity
Cathepsin s promotes human preadipocyte differentiation: possible involvement of fibronectin degradation.
Obesity
Characteristics of foot fractures in HIV-infected patients previously treated with tenofovir versus non-tenofovir-containing highly active antiretroviral therapy.
Obesity
Control of the adipsin gene in adipocyte differentiation. Identification of distinct nuclear factors binding to single- and double-stranded DNA.
Obesity
Enteropeptidase inhibition improves kidney function in a rat model of diabetic kidney disease.
Obesity
Enteropeptidase inhibitor SCO-792 effectively prevents kidney function decline and fibrosis in a rat model of chronic kidney disease.
Obesity
Expression of LONP1 Is High in Visceral Adipose Tissue in Obesity, and Is Associated with Glucose and Lipid Metabolism.
Obesity
Familial aggregation of abnormal ventilatory control and pulmonary function in chronic obstructive pulmonary disease.
Obesity
Functions of NQO1 in Cellular Protection and CoQ10 Metabolism and its Potential Role as a Redox Sensitive Molecular Switch.
Obesity
Genetic variation in the vaspin gene affects circulating serum vaspin concentrations.
Obesity
Human obesity and thinness, hyperlipidemia, hyperglycemia, and insulin resistance associated with HIV1 protease inhibitors. Prevention by alternating several antiproteases in short sequences.
Obesity
Inhibition of Serine Protease Activity Protects Against High Fat Diet-Induced Inflammation and Insulin Resistance.
Obesity
Loss of mitochondrial protease ClpP protects mice from diet-induced obesity and insulin resistance.
Obesity
Loss of mitochondrial protease OMA1 alters processing of the GTPase OPA1 and causes obesity and defective thermogenesis in mice.
Obesity
Membrane Phospholipids and Polyphosphates as Cofactors and Binding Molecules of SERPINA12 (vaspin).
Obesity
Metformin decreases the adipokine vaspin in overweight women with polycystic ovary syndrome concomitant with improvement in insulin sensitivity and a decrease in insulin resistance.
Obesity
Obesity is associated with poor response to clopidogrel and an increased susceptibility to protease activated receptor-1 mediated platelet activation.
Obesity
Pappa2 deletion alters IGFBPs but has little effect on glucose disposal or adiposity.
Obesity
Prevalence of Metabolic Syndrome in Patients with HIV in the Era of Highly Active Antiretroviral Therapy.
Obesity
Prevention and Reversal of Liver Damage following Biliopancreatic Diversion for Obesity.
Obesity
Role of vaspin in porcine ovary: effect on signaling pathways and steroid synthesis via GRP78 receptor and protein kinase A.
Obesity
S3-2, a novel long-lasting oxyntomodulin derivative, exerts improvement on diabesity and renal injury through activating GLP-1 and glucagon receptors.
Obesity
Serum visceral adipose tissue-derived serine protease inhibitor concentrations in human obesity and polycystic ovary syndrome.
Obesity
Structure?Activity Relationship and Molecular Docking of Natural Product Library Reveal Chrysin as a Novel Dipeptidyl Peptidase-4 (DPP-4) Inhibitor: An Integrated In Silico and In Vitro Study.
Obesity
The effect of protease inhibitors derived from potato formulated in a minidrink on appetite, food intake and plasma cholecystokinin levels in humans.
Obesity
The serine protease granzyme B as an inflammatory marker, in relation to the insulin receptor cleavage in human obesity and type 2 diabetes mellitus.
Obesity
Treatment with a fixed dose combination antiretroviral therapy drug containing tenofovir, emtricitabine and efavirenz is associated with cardioprotection in high calorie diet-induced obese rats.
Obesity
Vaspin is related to gender, puberty and deteriorating insulin sensitivity in children.
Obesity
Vaspin prevents elevation of blood pressure through inhibition of peripheral vascular remodeling in spontaneously hypertensive rats.
Obesity
Visceral adipose tissue-derived serine protease inhibitor: a unique insulin-sensitizing adipocytokine in obesity.
Obesity, Abdominal
A syndrome of lipoatrophy, lactic acidaemia and liver dysfunction associated with HIV nucleoside analogue therapy: contribution to protease inhibitor-related lipodystrophy syndrome.
Obesity, Abdominal
Cardiometabolic risk among HIV-POSITIVE Ugandan adults: prevalence, predictors and effect of long-term antiretroviral therapy.
Obesity, Abdominal
Effects of metformin or gemfibrozil on the lipodystrophy of HIV-infected patients receiving protease inhibitors.
Obesity, Abdominal
Human obesity and thinness, hyperlipidemia, hyperglycemia, and insulin resistance associated with HIV1 protease inhibitors. Prevention by alternating several antiproteases in short sequences.
Obesity, Abdominal
Minireview: weapons of lean body mass destruction: the role of ectopic lipids in the metabolic syndrome.
Obesity, Abdominal
Prevalence and incidence of diabetes in HIV-infected minority patients on protease inhibitors.
Obesity, Abdominal
Regulation of expression of 11beta-hydroxysteroid dehydrogenase type 1 in adipose tissue: tissue-specific induction by cytokines.
Obesity, Abdominal
Risk of lipodystrophy in HIV-1-infected patients treated with protease inhibitors: a prospective cohort study.
Obesity, Abdominal
Visceral obesity, hypertriglyceridemia and hypercortisolism in a boy with perinatally acquired HIV infection receiving protease inhibitor-containing antiviral treatment.
Obstetric Labor, Premature
Antenatal microbiologic and maternal risk factors associated with prematurity.
Obstetric Labor, Premature
Protease production by microorganisms associated with reproductive tract infection.
Odontogenic Cysts
Differential expression of protease inhibitor and small proline-rich protein genes between normal human oral tissue and odontogenic keratocysts.
Odontogenic Tumors
Immunohistochemical detection and distribution of enamelysin (MMP-20) in human odontogenic tumors.
Oligospermia
A novel frameshift mutation in ubiquitin-specific protease 26 gene in a patient with severe oligozoospermia.
Onychomycosis
Detection of Trichophyton rubrum and Trichophyton interdigitale in onychomycosis using monoclonal antibodies against Sub6 (Tri r 2).
Opisthorchiasis
Evaluation of liver fluke recombinant cathepsin B-1 protease as a serodiagnostic antigen for human opisthorchiasis.
Opisthorchiasis
Serum protease inhibitors in opisthorchiasis, hepatoma, cholangiocarcinoma, and other liver diseases.
Opportunistic Infections
A case-control study of HIV-associated pancreatic abnormalities during HAART era. Focus on emerging risk factors and specific management.
Opportunistic Infections
Challenges in providing comprehensive and coordinated care to HIV/AIDS patients: a Canadian perspective.
Opportunistic Infections
Changes in CD4+ cell count and the risk of opportunistic infection or death after highly active antiretroviral treatment. Groupe d'Epidémiologie Clinique du SIDA en Aquitaine.
Opportunistic Infections
Changing patterns in the neuropathogenesis of HIV during the HAART era.
Opportunistic Infections
Changing prevalence of oral manifestations of human immuno-deficiency virus in the era of protease inhibitor therapy.
Opportunistic Infections
Does HIV infection affect growth and puberty of Cameroonian children?
Opportunistic Infections
Factors predictive of disease progression and death in AIDS-related Kaposi's sarcoma.
Opportunistic Infections
HIV infection and the pancreas: risk factors and potential management guidelines.
Opportunistic Infections
HIV-Associated Thromboembolic Phenomenon due to Protein C Deficiency.
Opportunistic Infections
HIV-associated thromboembolic phenomenon due to protein C deficiency.
Opportunistic Infections
Identification and characterization of an aspartyl protease from Cryptococcus neoformans.
Opportunistic Infections
Improved prognosis in patients with acquired immunodeficiency syndrome-related lymphoma.
Opportunistic Infections
Influence of highly active anti-retroviral therapy on response to treatment and survival in patients with acquired immunodeficiency syndrome-related non-Hodgkin's lymphoma treated with cyclophosphamide, hydroxydoxorubicin, vincristine and prednisone.
Opportunistic Infections
Modeling changes in CD4-positive T-lymphocyte counts after the start of highly active antiretroviral therapy and the relation with risk of opportunistic infections: the Aquitaine Cohort, 1996-1997.
Opportunistic Infections
Osteonecrosis in patients infected with human immunodeficiency virus: a case-control study.
Opportunistic Infections
Protease inhibitor-based therapy is associated with decreased HIV-related health care costs in men treated at a Veterans Administration hospital.
Opportunistic Infections
Protease inhibitors: a therapeutic breakthrough for the treatment of patients with human immunodeficiency virus.
Opportunistic Infections
Re-emerging Aspartic Protease Targets: Examining Cryptococcus neoformans Major Aspartyl Peptidase 1 as a Target for Antifungal Drug Discovery.
Opportunistic Infections
Regression of acquired immunodeficiency syndrome-related pulmonary Kaposi's sarcoma after highly active antiretroviral therapy.
Opportunistic Infections
Relapsing visceral leishmaniasis in HIV-infected patients undergoing successful protease inhibitor therapy.
Opportunistic Infections
Risk factors for venous thromboembolism in patients with human immunodeficiency virus infection.
Opportunistic Infections
The human immunodeficiency virus (HIV) protease inhibitor indinavir directly affects the opportunistic fungal pathogen Cryptococcus neoformans.
Opportunistic Infections
The long-term outcomes of antiretroviral treatment initiated with mono or dual nucleoside reverse transcriptase inhibitors in HIV-1-infected children: an Asian observational study.
Opportunistic Infections
[Antiretroviral therapy for HIV-infected patients with schizophrenia. Coordinated multidisciplinary management (7 cases)]
Opportunistic Infections
[Prevention of opportunistic infections in the protease inhibitor era]
Opportunistic Infections
[Pulmonary thromboembolism in HIV infected admitted patients under 50 years old.]
Opportunistic Infections
[Treatment and prophylaxis of opportunistic infections in the course of HIV disease: a state of the art in 2004. Part 2: Viral, fungal and bacterial infections]
Optic Atrophy
Renal cold storage followed by transplantation impairs expression of key mitochondrial fission and fusion proteins.
Optic Nerve Injuries
Mechanisms governing neuronal degeneration and axonal regeneration in the mature retinofugal system.
Optic Nerve Injuries
The Relationship of Microglial Cells to Dying Neurons During Natural Neuronal Cell Death and Axotomy-induced Degeneration of the Rat Retina.
Oral Manifestations
Changing prevalence of oral manifestations of human immuno-deficiency virus in the era of protease inhibitor therapy.
Oral Manifestations
Impact of PI and NNRTI HAART-based therapy on oral lesions of Brazilian HIV-infected patients.
Orchitis
Micro-encapsulated secretory leukocyte protease inhibitor decreases cell-mediated immune response in autoimmune orchitis.
Oropharyngeal Neoplasms
Oral secretory leukocyte protease inhibitor (SLPI): Associations with oropharyngeal cancer and treatment outcome.
Orthomyxoviridae Infections
Tmprss2 is essential for influenza H1N1 virus pathogenesis in mice.
Osteoarthritis
A new model of osteoarthritis in rabbits. III. Evaluation of anti-osteoarthritic effects of selected drugs administered intraarticularly.
Osteoarthritis
Association of osteoarthritis with homozygosity for a 5.8 kb Taq I fragment of the alpha 1-antichymotrypsin gene.
Osteoarthritis
CD56(+)/CD16(-) Natural Killer cells expressing the inflammatory protease granzyme A are enriched in synovial fluid from patients with osteoarthritis.
Osteoarthritis
Characteristics of the protease activity in synovial fluid from patients with rheumatoid arthritis and osteoarthritis.
Osteoarthritis
Demonstration of granzyme A and perforin messenger RNA in the synovium of patients with rheumatoid arthritis.
Osteoarthritis
Development of a Protease Biosensor Based on a Dimerization-Dependent Red Fluorescent Protein.
Osteoarthritis
Discovery and characterization of a novel inhibitor of matrix metalloprotease-13 that reduces cartilage damage in vivo without joint fibroplasia side effects.
Osteoarthritis
Distinct expression of mast cell tryptase and protease activated receptor-2 in synovia of rheumatoid arthritis and osteoarthritis.
Osteoarthritis
Engineering of TIMP-3 as a LAP-fusion protein for targeting to sites of inflammation.
Osteoarthritis
Expression and activity profiling of selected cysteine cathepsins and matrix metalloproteinases in synovial fluids from patients with rheumatoid arthritis and osteoarthritis.
Osteoarthritis
Further characterization of a neutral metalloprotease isolated from human articular cartilage.
Osteoarthritis
High throughput screening of potentially selective MMP-13 exosite inhibitors utilizing a triple-helical FRET substrate.
Osteoarthritis
HtrA1 Is Specifically Up-Regulated in Active Keloid Lesions and Stimulates Keloid Development.
Osteoarthritis
Human and bovine articular cartilage loading measured with a new resistive sensor: effects of protease degradation and osteoarthritis.
Osteoarthritis
Hyaluronan suppresses enhanced cathepsin K expression via activation of NF-?B with mechanical stress loading in a human chondrocytic HCS-2/8 cells.
Osteoarthritis
Identification of a Novel HtrA1-susceptible cleavage site in human aggrecan: evidence for the involvement of HtrA1 in aggrecan proteolysis in vivo.
Osteoarthritis
Identification of novel, exosite-binding matrix metalloproteinase-13 inhibitor scaffolds.
Osteoarthritis
IL-15 and IL15RA in Osteoarthritis: Association With Symptoms and Protease Production, but Not Structural Severity.
Osteoarthritis
In vivo fluorescence reflectance imaging of protease activity in a mouse model of post-traumatic osteoarthritis.
Osteoarthritis
Joint immobilisation prevents murine osteoarthritis, and reveals the highly mechanosensitive nature of protease expression in vivo.
Osteoarthritis
Licofelone reduces progression of structural changes in a canine model of osteoarthritis under curative conditions: effect on protease expression and activity.
Osteoarthritis
Meta-analyses of genes modulating intracellular T3 bio-availability reveal a possible role for the DIO3 gene in osteoarthritis susceptibility.
Osteoarthritis
Microparticle-induced release of B-lymphocyte regulators by rheumatoid synoviocytes.
Osteoarthritis
Oral treatment with a Brachystemma calycinum D. don plant extract reduces disease symptoms and the development of cartilage lesions in experimental dog osteoarthritis: inhibition of protease activated receptor-2 (PAR-2).
Osteoarthritis
Osteochondral angiogenesis and increased protease inhibitor expression in OA.
Osteoarthritis
Overexpression of secretory leukocyte peptidase inhibitor (SLPI) does not modulate experimental osteoarthritis but may be a biomarker for the disease.
Osteoarthritis
Plasmin, plasminogen activators and inhibitor in human osteoarthritic cartilage.
Osteoarthritis
Protease activated receptor 2 and matriptase expression in the joints of cats with and without osteoarthritis.
Osteoarthritis
Protease-activated receptor 2: a novel pathogenic pathway in a murine model of osteoarthritis.
Osteoarthritis
Quantification of protease activities in synovial fluid from rheumatoid and osteoarthritis cases: comparison with antioxidant and free radical damage markers.
Osteoarthritis
Regulation of tumor necrosis factor-alpha and tumor necrosis factor converting enzyme in human osteoarthritis.
Osteoarthritis
Screening of potential a disintegrin and metalloproteinase with thrombospondin motifs-4 inhibitors using a collagen model fluorescence resonance energy transfer substrate.
Osteoarthritis
SPRY4 acts as an indicator of osteoarthritis severity and regulates chondrocyte hypertrophy and ECM protease expression.
Osteoarthritis
Tenascin-C fragments are endogenous inducers of cartilage matrix degradation.
Osteoarthritis
The role of alpha-1-protease inhibitor (A1PI) in the inhibition of protease activity in human knee osteoarthritis.
Osteoarthritis
The serine protease inhibitor trappin-2 is present in cartilage and synovial fluid in osteoarthritis.
Osteoarthritis
Tissue IGFBP-3 proteolysis: contrasting pathophysiology to that in the circulation.
Osteoarthritis
TNF-alpha convertase enzyme from human arthritis-affected cartilage: isolation of cDNA by differential display, expression of the active enzyme, and regulation of TNF-alpha.
Osteoarthritis
[The effectiveness of the protease inhibitor Contrykal in the drug therapy of arthrosis deformans]
Osteoarthritis, Knee
The role of alpha-1-protease inhibitor (A1PI) in the inhibition of protease activity in human knee osteoarthritis.
Osteochondrodysplasias
Undersulfated chondroitin sulfate in cartilage from a miniature poodle with spondyloepiphyseal dysplasia.
Osteogenesis Imperfecta
BMP1 and TLL1 Are Required for Maintaining Periodontal Homeostasis.
Osteogenesis Imperfecta
Consequences of Glycine Mutations in the Fibronectin-binding Sequence of Collagen.
Osteogenesis Imperfecta
Gly85 to Val substitution in pro alpha 1(I) chain causes mild osteogenesis imperfecta and introduces a susceptibility to protease digestion.
Osteomyelitis
A secreted bacterial protease tailors the Staphylococcus aureus virulence repertoire to modulate bone remodeling during osteomyelitis.
Osteomyelitis
[Protease mechanism of changes in fibrinolytic activity of blood in hematogenic osteomyelitis in children]
Osteomyelitis
[Treatment of experimental osteomyelitis with dimexid, protease inhibitors and proteolytic enzymes]
Osteonecrosis
Avascular necrosis of bone in patients with human immunodeficiency virus infection: report of 6 cases and review of the literature.
Osteonecrosis
Hyperlipidaemia a risk factor for femoral head osteonecrosis (Legg-Calv -Perthes-like disease) in children with AIDS: case report.
Osteonecrosis
Iatrogenic Cushing syndrome and multifocal osteonecrosis caused by the interaction between inhaled fluticasone and ritonavir.
Osteonecrosis
Osteonecrosis in patients infected with human immunodeficiency virus: a case-control study.
Osteonecrosis
Symptomatic bone disorders in HIV-infected patients: incidence in the Aquitaine cohort (1999-2002).
Osteopetrosis
Impaired bone resorption in cathepsin K-deficient mice is partially compensated for by enhanced osteoclastogenesis and increased expression of other proteases via an increased RANKL/OPG ratio.
Osteophyte
Osteophytes and fracture calluses share developmental milestones and are diminished by unloading.
Osteoporosis
Accelerated bone mineral loss in HIV-infected patients receiving potent antiretroviral therapy.
Osteoporosis
Antiretroviral therapy and the prevalence of osteopenia and osteoporosis: a meta-analytic review.
Osteoporosis
Associations between osteoporosis and drug exposure: A post-marketing study of the World Health Organization pharmacovigilance database (VigiBase®).
Osteoporosis
Characteristics of foot fractures in HIV-infected patients previously treated with tenofovir versus non-tenofovir-containing highly active antiretroviral therapy.
Osteoporosis
EVALUATION OF BONE RESORPTIVE POTENTIAL IN THE TREATMENT OF GENERALIZED PERIODONTITIS.
Osteoporosis
Frailty in HIV infected people: a new risk factor for bone mineral density loss.
Osteoporosis
Heel quantitative ultrasound in HIV-infected patients: a cross-sectional study.
Osteoporosis
HIV envelope gp120-mediated regulation of osteoclastogenesis via receptor activator of nuclear factor kappa B ligand (RANKL) secretion and its modulation by certain HIV protease inhibitors through interferon-gamma/RANKL cross-talk.
Osteoporosis
Iatrogenic Cushing's syndrome with osteoporosis and secondary adrenal failure in human immunodeficiency virus-infected patients receiving inhaled corticosteroids and ritonavir-boosted protease inhibitors: six cases.
Osteoporosis
Incidence and prevalence of medication-induced osteoporosis: evidence-based review.
Osteoporosis
Proteolytic activity of human osteoclast cathepsin K. Expression, purification, activation, and substrate identification.
Osteoporosis
Rat cathepsin K: Enzymatic specificity and regulation of its collagenolytic activity.
Osteoporosis
Role of plasminogen activator inhibitor-1 in glucocorticoid-induced muscle change in mice.
Osteoporosis
Substrate-derived triazolo- and azapeptides as inhibitors of cathepsins K and S.
Osteoporosis
Symptomatic bone disorders in HIV-infected patients: incidence in the Aquitaine cohort (1999-2002).
Osteoporosis
Timing, Dosage, and Adherence of Antiretroviral Therapy and Risk of Osteoporosis in Patients With Human Immunodeficiency Virus Infection in Taiwan: A Nested Case-Control Study.
Osteoporosis, Postmenopausal
Regulation of insulin-like growth factor-binding protein-4 protease activity by estrogen and parathyroid hormone in SaOS-2 cells: implications for the pathogenesis of postmenopausal osteoporosis.
Osteosarcoma
ADAM-9 is an insulin-like growth factor binding protein-5 protease produced and secreted by human osteoblasts.
Osteosarcoma
Downregulation of Ubiquitin-Specific Protease 22 Inhibits Proliferation, Invasion, and Epithelial-Mesenchymal Transition in Osteosarcoma Cells.
Osteosarcoma
Evidence that human bone cells in culture produce insulin-like growth factor-binding protein-4 and -5 proteases.
Osteosarcoma
Expression of the ectodomain-releasing protease ADAM17 is directly regulated by the osteosarcoma and bone-related transcription factor RUNX2.
Osteosarcoma
MALT1 is a critical mediator of PAR1-driven NF-?B activation and metastasis in multiple tumor types.
Osteosarcoma
MicroRNA-192-5p suppresses the initiation and progression of osteosarcoma by targeting USP1.
Osteosarcoma
miR-140 inhibits osteosarcoma progression by impairing USP22-mediated LSD1 stabilization and promoting p21 expression.
Osteosarcoma
Mitofilin is a transmembrane protein of the inner mitochondrial membrane expressed as two isoforms.
Osteosarcoma
Negative growth control of osteosarcoma cell by Bowman-Birk protease inhibitor from soybean; involvement of connexin 43.
Osteosarcoma
Target-activated transcription for the amplified sensing of protease biomarkers.
Otitis
[Effect of enzymes of the protease and nuclease groups on Eustachian tube function in patients with chronic suppurative otitis]
Otitis Externa
Protease activities of Candida spp. isolated from otitis externa: preliminary result.
Otitis Media
Antiinflammatory effects of a corticosteroid and protease inhibitor agents on antigen-induced otitis media in chinchillas.
Otitis Media
Biochemical study of protease inhibitors in experimental otitis media with effusion.
Otitis Media
Endotoxin and lysosomal protease activity in acute and chronic otitis media with effusion.
Otitis Media
Otitis media in Brazilian human immunodeficiency virus infected children undergoing antiretroviral therapy.
Otitis Media
Otitis media in children with vertically-acquired HIV infection: the Great Ormond Street Hospital experience.
Otitis Media
Protease inhibitors alpha1-antitrypsin and ilomastat are not ototoxic in the chinchilla.
Otitis Media
Protease inhibitors in middle ear effusions from experimental otitis media with effusion: kinetics of alpha 1-antitrypsin and alpha 2-macroglobulin levels.
Otitis Media
Proteases and protease inhibitors in immune complex otitis media in chinchillas.
Otitis Media
The significance of protease inhibitors in the pathogenesis of otitis media with effusion.
Otitis Media with Effusion
Activities of antiplasmin and antiplasminogen activator in serous middle ear effusions.
Otitis Media with Effusion
Alpha 1-antitrypsin and ilomastat inhibit inflammatory proteases present in human middle ear effusions.
Otitis Media with Effusion
Biochemical study of protease inhibitors in experimental otitis media with effusion.
Otitis Media with Effusion
Endotoxin and lysosomal protease activity in acute and chronic otitis media with effusion.
Otitis Media with Effusion
Granulocyte protease inhibition in acute and chronic middle ear effusion.
Otitis Media with Effusion
Kinetics of lysosomal protease activity in human otitis media with effusion.
Otitis Media with Effusion
Protease inhibitors in middle ear effusions from experimental otitis media with effusion: kinetics of alpha 1-antitrypsin and alpha 2-macroglobulin levels.
Otitis Media with Effusion
The significance of protease inhibitors in the pathogenesis of otitis media with effusion.
Otitis Media with Effusion
Vascular permeability of the middle ear mucosa in otitis media with effusion.
Otomycosis
Protease activities of Candida spp. isolated from otitis externa: preliminary result.
Otosclerosis
[The genetics of the protease inhibitor system and osteospongiosis. Statistical study in 199 patients]
Ovarian Cysts
Use of serum secretory leukocyte protease inhibitor levels in patients to improve specificity of ovarian cancer diagnosis.
Ovarian Cysts
[Placental protein 5 and pregnancy zone protein in ovarian cysts and benign cystic ovarian tumors]
Ovarian Diseases
Blood and lymphatic vasculature in the ovary: development, function and disease.
Ovarian Diseases
Minireview: weapons of lean body mass destruction: the role of ectopic lipids in the metabolic syndrome.
Ovarian Neoplasms
A kunitz-type protease inhibitor bikunin disrupts ligand-induced oligomerization of receptors for transforming growth factor (TGF)-beta and subsequently suppresses TGF-beta signalings.
Ovarian Neoplasms
A Kunitz-type protease inhibitor, bikunin, inhibits ovarian cancer cell invasion by blocking the calcium-dependent transforming growth factor-beta 1 signaling cascade.
Ovarian Neoplasms
A novel protease homolog differentially expressed in breast and ovarian cancer.
Ovarian Neoplasms
Activation and enzymatic characterization of recombinant human kallikrein 8.
Ovarian Neoplasms
Advanced high-grade serous ovarian cancer: inverse association of KLK13 and KLK14 mRNA levels in tumor tissue and patients' prognosis.
Ovarian Neoplasms
Aging issues in invasion and metastasis. Fertile ground for investigation.
Ovarian Neoplasms
c-Met overexpression is a prognostic factor in ovarian cancer and an effective target for inhibition of peritoneal dissemination and invasion.
Ovarian Neoplasms
Cathepsin B mediates the pH-dependent proinvasive activity of tumor-shed microvesicles.
Ovarian Neoplasms
Cathepsin D non-proteolytically induces proliferation and migration in human omental microvascular endothelial cells via activation of the ERK1/2 and PI3K/AKT pathways.
Ovarian Neoplasms
Constitutive and lysophosphatidic acid (LPA)-induced LPA production: role of phospholipase D and phospholipase A2.
Ovarian Neoplasms
Decreased expression of long non-coding RNA GAS5 promotes cell proliferation, migration and invasion, and indicates a poor prognosis in ovarian cancer.
Ovarian Neoplasms
Defective cytochrome c-dependent caspase activation in ovarian cancer cell lines due to diminished or absent apoptotic protease activating factor-1 activity.
Ovarian Neoplasms
Disease processes may be reflected by correlations among tissue kallikrein proteases but not with proteolytic factors uPA and PAI-1 in primary ovarian carcinoma.
Ovarian Neoplasms
Effect of small interfering RNA transfection on FAK and DLC1 mRNA expression in OVCAR-3.
Ovarian Neoplasms
Effects of synthetic peptides and protease inhibitors on the interaction of a human ovarian cancer cell line (NIH:OVCAR-3) with a reconstituted basement membrane (Matrigel).
Ovarian Neoplasms
Effects of the Bowman-Birk inhibitor on clonogenic survival and cisplatin- or radiation-induced cytotoxicity in human breast, cervical, and head and neck cancer cells.
Ovarian Neoplasms
Elafin is downregulated during breast and ovarian tumorigenesis but its residual expression predicts recurrence.
Ovarian Neoplasms
Elevated serum CXCL16 is an independent predictor of poor survival in ovarian cancer and may reflect pro-metastatic ADAM protease activity.
Ovarian Neoplasms
ERMP1, a novel potential oncogene involved in UPR and oxidative stress defense, is highly expressed in human cancer.
Ovarian Neoplasms
Genetic down-regulation of phosphoinositide 3-kinase by bikunin correlates with suppression of invasion and metastasis in human ovarian cancer HRA cells.
Ovarian Neoplasms
Hepatocyte growth factor is a preferred in vitro substrate for human hepsin, a membrane-anchored serine protease implicated in prostate and ovarian cancers.
Ovarian Neoplasms
Hepsin, a cell surface serine protease identified in hepatoma cells, is overexpressed in ovarian cancer.
Ovarian Neoplasms
Heterogeneous expression of serine protease inhibitor maspin in ovarian cancer.
Ovarian Neoplasms
High-temperature requirement factor A3 (Htra3): a novel serine protease and its potential role in ovarian function and ovarian cancers.
Ovarian Neoplasms
HtrA1 sensitizes ovarian cancer cells to cisplatin-induced cytotoxicity by targeting XIAP for degradation.
Ovarian Neoplasms
Human Epididymis Protein 4 and Secretory Leukocyte Protease Inhibitor in Vaginal Fluid: Relation to Vaginal Components and Bacterial Composition.
Ovarian Neoplasms
Human kallikrein 6 activity is regulated via an autoproteolytic mechanism of activation/inactivation.
Ovarian Neoplasms
Identification and analysis of mammalian KLK6 orthologue genes for prediction of physiological substrates.
Ovarian Neoplasms
Impact of platinum-based chemotherapy on circulating nucleic acid levels, protease activities in blood and disseminated tumor cells in bone marrow of ovarian cancer patients.
Ovarian Neoplasms
Improved detection of ovarian cancer metastases by intraoperative quantitative fluorescence protease imaging in a pre-clinical model.
Ovarian Neoplasms
Increased expression of matrix metalloproteinases (MMP)-2, MMP-9, and the urokinase-type plasminogen activator is associated with progression from benign to advanced ovarian cancer.
Ovarian Neoplasms
Kallikrein family proteases KLK6 and KLK7 are potential early detection and diagnostic biomarkers for serous and papillary serous ovarian cancer subtypes.
Ovarian Neoplasms
Lysophosphatidic acid induces tumor necrosis factor-alpha to regulate a pro-inflammatory cytokine network in ovarian cancer.
Ovarian Neoplasms
Lysophosphatidic Acid Stimulates Ovarian Cancer Cell Migration via a Ras-MEK Kinase 1 Pathway.
Ovarian Neoplasms
Mass spectrometry-based peptidome profiling of human serous ovarian cancer tissues.
Ovarian Neoplasms
Overexpression of miRNA-221 promotes cell proliferation by targeting the apoptotic protease activating factor-1 and indicates a poor prognosis in ovarian cancer.
Ovarian Neoplasms
Overexpression of protease inhibitor-dead secretory leukocyte protease inhibitor causes more aggressive ovarian cancer in vitro and in vivo.
Ovarian Neoplasms
Overview of transcriptomic analysis of all human proteases, non-proteolytic homologs and inhibitors: Organ, tissue and ovarian cancer cell line expression profiling of the human protease degradome by the CLIP-CHIP DNA microarray.
Ovarian Neoplasms
PAR2 induces ovarian cancer cell motility by merging three signalling pathways to transactivate EGFR.
Ovarian Neoplasms
Paracrine SLPI secretion upregulates MMP-9 transcription and secretion in ovarian cancer cells.
Ovarian Neoplasms
Phosphatidylinositol 3-kinase/Akt regulates the balance between plasminogen activator inhibitor-1 and urokinase to promote migration of SKOV-3 ovarian cancer cells.
Ovarian Neoplasms
Prognostic significance of urokinase (uPA) and its inhibitor PAI-1 for survival in advanced ovarian carcinoma stage FIGO IIIc.
Ovarian Neoplasms
Protease Cargo in Circulating Exosomes of Breast Cancer and Ovarian Cancer Patients
Ovarian Neoplasms
PRSS21/testisin inhibits ovarian tumor metastasis and antagonizes proangiogenic angiopoietins ANG2 and ANGPTL4.
Ovarian Neoplasms
Role of plasmin in the degradation of the stroma-derived fibrin in human ovarian carcinoma.
Ovarian Neoplasms
Role of protease activated receptor-2 in tumor advancement of ovarian cancers.
Ovarian Neoplasms
Secretory leukocyte protease inhibitor antagonizes paclitaxel in ovarian cancer cells.
Ovarian Neoplasms
Secretory leukocyte protease inhibitor is a survival and proliferation factor for castration-resistant prostate cancer.
Ovarian Neoplasms
Secretory leukocyte protease inhibitor modulates urethane-induced lung carcinogenesis.
Ovarian Neoplasms
Serine protease inhibition and mitochondrial dysfunction associated with cisplatin resistance in human tumor cell lines: targets for therapy.
Ovarian Neoplasms
Serine protease inhibitor Kazal type 1 (SPINK1) drives proliferation and anoikis resistance in a subset of ovarian cancers.
Ovarian Neoplasms
SLPI promotes the gastric cancer growth and metastasis by regulating the expression of P53, Bcl-2 and Caspase-8.
Ovarian Neoplasms
Synthetic Circuit-Driven Expression of Heterologous Enzymes for Disease Detection.
Ovarian Neoplasms
Testisin, a glycosyl-phosphatidylinositol-linked serine protease, promotes malignant transformation in vitro and in vivo.
Ovarian Neoplasms
The alarm anti-protease, secretory leukocyte protease inhibitor, is a proliferation and survival factor for ovarian cancer cells.
Ovarian Neoplasms
The HIV protease inhibitor saquinavir induces endoplasmic reticulum stress, autophagy, and apoptosis in ovarian cancer cells.
Ovarian Neoplasms
The human kallikrein protein 5 (hK5) is enzymatically active, glycosylated and forms complexes with two protease inhibitors in ovarian cancer fluids.
Ovarian Neoplasms
The serine protease prostasin (PRSS8) is a potential biomarker for early detection of ovarian cancer.
Ovarian Neoplasms
The transmembrane protease serine (TMPRSS3/TADG-12) D variant: a potential candidate for diagnosis and therapeutic intervention in ovarian cancer.
Ovarian Neoplasms
Thrombomodulin, a receptor for the serine protease thrombin, is decreased in primary tumors and metastases but increased in ascitic fluids of patients with advanced ovarian cancer FIGO IIIc.
Ovarian Neoplasms
Tissue factor-factor VIIa complex triggers protease activated receptor 2-dependent growth factor release and migration in ovarian cancer.
Ovarian Neoplasms
TMPRSS3 modulates ovarian cancer cell proliferation, invasion and metastasis.
Ovarian Neoplasms
Transforming growth factor-beta1 produced by ovarian cancer cell line HRA stimulates attachment and invasion through an up-regulation of plasminogen activator inhibitor type-1 in human peritoneal mesothelial cells.
Ovarian Neoplasms
Transmembrane serine protease TADG-15 (ST14/Matriptase/MT-SP1): expression and prognostic value in ovarian cancer.
Ovarian Neoplasms
Ubiquitin-specific protease 14 regulates ovarian cancer cisplatin-resistance by stabilizing BCL6 oncoprotein.
Ovarian Neoplasms
Upregulation of bikunin in tumor-infiltrating macrophages as a factor of favorable prognosis in ovarian cancer.
Ovarian Neoplasms
Urokinase (uPA) and PAI-1 predict survival in advanced ovarian cancer patients (FIGO III) after radical surgery and platinum-based chemotherapy.
Ovarian Neoplasms
Use of serum secretory leukocyte protease inhibitor levels in patients to improve specificity of ovarian cancer diagnosis.
Ovarian Neoplasms
USP1 links platinum resistance to cancer cell dissemination by regulating Snail stability.
Ovarian Neoplasms
Utility of Progranulin and Serum Leukocyte Protease Inhibitor as Diagnostic and Prognostic Biomarkers in Ovarian Cancer.
Ovarian Neoplasms
Visualizing protein-ligand binding with chemical energy-wise decomposition (CHEWD): application to ligand binding in the kallikrein-8 S1 Site.
Ovarian Neoplasms
[Determination of tumor-associated trypsin inhibitor (TATI) in subjects with gastrointestinal diseases. Preliminary data]
Overweight
Expression of LONP1 Is High in Visceral Adipose Tissue in Obesity, and Is Associated with Glucose and Lipid Metabolism.
Overweight
Leveraging routine viral load testing to integrate diabetes screening among patients on antiretroviral therapy in Malawi.
Overweight
Metabolic disorders and cardiovascular risk in treatment-naïve HIV-infected patients of Sub-Saharan origin starting antiretrovirals: impact of westernized lifestyle.
Overweight
Overweight HIV patients with abdominal fat distribution treated with protease inhibitors are at high risk for abnormalities in glucose metabolism - a reason for glycemic control.
Pancreatic Cyst
Global Protease Activity Profiling Provides Differential Diagnosis of Pancreatic Cysts.
Pancreatic Diseases
Efficacy of camostat mesilate against dyspepsia associated with non-alcoholic mild pancreatic disease.
Pancreatic Diseases
Roles of serine protease inhibitor Kazal type 1 (SPINK1) in pancreatic diseases.
Pancreatic Diseases
Serum protease inhibitor capacity for elastase and the severity of pancreatitis.
Pancreatic Fistula
Canine pancreatic responses to intestinally perfused proteins and protein digests.
Pancreatic Fistula
Early intraperitoneal metabolic changes and protease activation as indicators of pancreatic fistula after pancreaticoduodenectomy.
Pancreatic Fistula
[Topical treatment of duodenal and pancreatic fistulas with protease inhibitors]
Pancreatic Neoplasms
A novel peptide-based electrochemical biosensor for the determination of a metastasis-linked protease in pancreatic cancer cells.
Pancreatic Neoplasms
A novel transmembrane serine protease (TMPRSS3) overexpressed in pancreatic cancer.
Pancreatic Neoplasms
A phase I study of full-dose gemcitabine and regional arterial infusion of nafamostat mesilate for advanced pancreatic cancer.
Pancreatic Neoplasms
A Thai family with hereditary pancreatitis and increased cancer risk due to a mutation in PRSS1 gene.
Pancreatic Neoplasms
Antiproteases in preventing the invasive potential of pancreatic cancer cells.
Pancreatic Neoplasms
CFTR, SPINK1, PRSS1, and CTRC Mutations Are Not Associated With Pancreatic Cancer in German Patients.
Pancreatic Neoplasms
Cloning of a new Kunitz-type protease inhibitor with a putative transmembrane domain overexpressed in pancreatic cancer.
Pancreatic Neoplasms
Combination chemotherapy of nafamostat mesilate with gemcitabine for pancreatic cancer targeting NF-kappaB activation.
Pancreatic Neoplasms
Combination chemotherapy of serine protease inhibitor nafamostat mesilate with oxaliplatin targeting NF-?B activation for pancreatic cancer.
Pancreatic Neoplasms
Completion Pancreaticoduodenectomy for Hereditary Pancreatitis After Prior Puestow Procedure: A Case Report.
Pancreatic Neoplasms
Concentrations of protease and anti-protease in serum of patients with pancreatic cancer.
Pancreatic Neoplasms
Dabigatran potentiates gemcitabine-induced growth inhibition of pancreatic cancer in mice.
Pancreatic Neoplasms
Designing protease sensors for real-time imaging of trypsin activation in pancreatic cancer cells.
Pancreatic Neoplasms
Deubiquitinase USP18 promotes the progression of pancreatic cancer via enhancing the Notch1-c-Myc axis.
Pancreatic Neoplasms
Doxycycline Inhibits Cancer Stem Cell-Like Properties via PAR1/FAK/PI3K/AKT Pathway in Pancreatic Cancer.
Pancreatic Neoplasms
Dual inhibition of nuclear factor kappa-B and Mdm2 enhance the antitumor effect of radiation therapy for pancreatic cancer.
Pancreatic Neoplasms
Effect of synthetic protease inhibitor on histologic changes and free radical activity in hamsters with pancreatic cancer.
Pancreatic Neoplasms
Hereditary pancreatitis as the premalignant disease: a Japanese case of pancreatic cancer involving the SPINK1 gene mutation N34S.
Pancreatic Neoplasms
Heterogeneities of attachment, chemotaxis, and protease production among clones with different metastatic potentials from a human pancreatic cancer cell line.
Pancreatic Neoplasms
Highly sensitive detection of early-stage pancreatic cancer by multimodal near-infrared molecular imaging in living mice.
Pancreatic Neoplasms
Identification and preclinical testing of a reversible cathepsin protease inhibitor reveals anti-tumor efficacy in a pancreatic cancer model.
Pancreatic Neoplasms
Identification of various types of ?2-HS glycoprotein in sera of patients with pancreatic cancer: Possible implication in resistance to protease treatment.
Pancreatic Neoplasms
In-silico analysis of kallikrein gene expression in pancreatic and colon cancers.
Pancreatic Neoplasms
Inhibition and mechanism of action of a protease inhibitor in human pancreatic cancer cells.
Pancreatic Neoplasms
Inhibition of LONP1 Suppresses Pancreatic Cancer Progression Via c-Jun N-Terminal Kinase Pathway-Meditated Epithelial-Mesenchymal Transition.
Pancreatic Neoplasms
Inhibitory effect of a serine protease inhibitor, FOY-305 on the invasion and metastasis of human pancreatic cancers.
Pancreatic Neoplasms
Is There a Trojan Horse to Aggressive Pancreatic Cancer Biology? A Review of the Trypsin-PAR2 Axis to Proliferation, Early Invasion, and Metastasis.
Pancreatic Neoplasms
Mechanisms of synthetic serine protease inhibitor (FUT-175)-mediated cell death.
Pancreatic Neoplasms
Mutations N34S and P55S of the SPINK1 gene in patients with chronic pancreatitis or pancreatic cancer and in healthy subjects: a report from Finland.
Pancreatic Neoplasms
Nafamostat mesilate can prevent adhesion, invasion and peritoneal dissemination of pancreatic cancer thorough nuclear factor kappa-B inhibition.
Pancreatic Neoplasms
Novel mutations of PRSS1 gene in patients with pancreatic cancer among Han population.
Pancreatic Neoplasms
Optimizing the Profile of [99mTc]Tc-NT(7-13) Tracers in Pancreatic Cancer Models by Means of Protease Inhibitors.
Pancreatic Neoplasms
p202, an interferon-inducible protein, mediates multiple antitumor activities in human pancreatic cancer xenograft models.
Pancreatic Neoplasms
Pancreatic cancer: the role of pancreatic stellate cells in tumor progression.
Pancreatic Neoplasms
Pancreatic stellate cells potentiate proinvasive effects of SERPINE2 expression in pancreatic cancer xenograft tumors.
Pancreatic Neoplasms
Phase II Study of Gemcitabine in Combination With Regional Arterial Infusion of Nafamostat Mesilate for Advanced Pancreatic Cancer.
Pancreatic Neoplasms
Plasma islet amyloid polypeptide is not an effective tumor marker for pancreatic cancer even when protease inhibitors and rapid freezing of specimens are utilized.
Pancreatic Neoplasms
Plasma membrane associated protease activity in human pancreatic cancer.
Pancreatic Neoplasms
Prevention of early liver metastasis after pancreatectomy by perioperative administration of a nuclear factor-?B inhibitor in mice.
Pancreatic Neoplasms
Protease activated receptor-2 induces migration of pancreatic cancer cells in an extracellular ATP dependent manner.
Pancreatic Neoplasms
Rapid characterization of candidate biomarkers for pancreatic cancer using cell microarrays (CMAs).
Pancreatic Neoplasms
Role of urokinase-type plasminogen activator and inhibitory effect of protease inhibitor in invasion and metastasis of pancreatic cancer.
Pancreatic Neoplasms
Secretory leukocyte protease inhibitor is a proliferation and survival factor for pancreatic cancer cells.
Pancreatic Neoplasms
Serine protease inhibitor Kazal type 1 and epidermal growth factor receptor are expressed in pancreatic tubular adenocarcinoma, intraductal papillary mucinous neoplasm, and pancreatic intraepithelial neoplasia.
Pancreatic Neoplasms
Serine protease inhibitor Kazal type 1 promotes proliferation of pancreatic cancer cells through the epidermal growth factor receptor.
Pancreatic Neoplasms
Synthetic serine protease inhibitor, gabexate mesilate, prevents nuclear factor-kappaB activation and increases TNF-alpha-mediated apoptosis in human pancreatic cancer cells.
Pancreatic Neoplasms
The construction and proliferative effects of a lentiviral vector capable of stably overexpressing SPINK1 gene in human pancreatic cancer AsPC-1 cell line.
Pancreatic Neoplasms
TMPRSS4 Promotes Cell Proliferation and Inhibits Apoptosis in Pancreatic Ductal Adenocarcinoma by Activating ERK1/2 Signaling Pathway.
Pancreatic Neoplasms
Trypsin-protease activated receptor-2 signaling contributes to pancreatic cancer pain.
Pancreatic Neoplasms
Ubiquitin-specific protease 4 predicts an unfavorable prognosis and promotes malignant behaviors in vitro in pancreatic cancer.
Pancreatic Neoplasms
Ubiquitin?specific protease 22?induced autophagy is correlated with poor prognosis of pancreatic cancer.
Pancreatic Neoplasms
Workshop report from the Division of Cancer Etiology, National Cancer Institute, National Institutes of Health. Protease inhibitors as cancer chemopreventive agents.
Pancreatic Neoplasms
[Effect of synthetic protease inhibitor on the oncogenesis of pancreatic cancer in hamsters: study on pancreatic endocrine cells and free radicals]
Pancreatic Neoplasms
[Inhibitory effect of FOY-305 on liver metastasis of the pancreatic cancer]
Pancreatic Pseudocyst
Pancreatic pseudocysts: a biochemical evaluation of proteases and protease inhibitors in plasma.
Pancreatitis
"Cocktail" therapy for acute pancreatitis: combined therapy of protease inhibitor, xanthine oxidase inhibitor and platelet activating factor antagonist in rat caerulein-induced pancreatis.
Pancreatitis
A new synthetic protease inhibitor, E-3123, prevents lysosomal and mitochondrial fragility in rat caerulein-induced pancreatitis.
Pancreatitis
A new synthetic protease inhibitor, E-3123, reduces organelle fragility of acinar cells in rat caerulein pancreatitis.
Pancreatitis
A Paper-Based Near-Infrared Optical Biosensor for Quantitative Detection of Protease Activity Using Peptide-Encapsulated SWCNTs.
Pancreatitis
A ten-year analysis of the incidence and risk factors for acute pancreatitis requiring hospitalization in an urban HIV clinical cohort.
Pancreatitis
A Thai family with hereditary pancreatitis and increased cancer risk due to a mutation in PRSS1 gene.
Pancreatitis
Absence of the neutrophil serine protease cathepsin G decreases neutrophil granulocyte infiltration but does not change the severity of acute pancreatitis.
Pancreatitis
Activation of trypsinogen in experimental models of acute pancreatitis in rats.
Pancreatitis
Acute hypercalcemia causes acute pancreatitis and ectopic trypsinogen activation in the rat.
Pancreatitis
Acute ischemic pancreatitis associated with acute type B aortic dissection: a case report.
Pancreatitis
Acute Myocardial Infarction in a 34-Year-Old HIV-Positive Female Patient While Undergoing Active Antiretroviral Therapy Containing a Protease Inhibitor.
Pancreatitis
Acute pancreatitis associated with different combination therapies in patients infected with human immunodeficiency virus.
Pancreatitis
Acute pancreatitis in HIV-infected patients: are etiologies changing since the introduction of protease inhibitor therapy?
Pancreatitis
Acute pancreatitis in man. A clinical and biochemical study of pathophysiology and treatment.
Pancreatitis
Acute pancreatitis. The correlation between clinical course, protease inhibitors, and complement and kinin activation.
Pancreatitis
Acute Pancreatitis: Hypertonic Saline Increases Heat Shock Proteins 70 and 90 and Reduces Neutrophil Infiltration in Lung Injury.
Pancreatitis
Adjuvant treatment of severe acute pancreatitis with C1 esterase inhibitor concentrate after haematopoietic stem cell transplantation.
Pancreatitis
Alpha-1-antichymotrypsin is an effective inhibitor of pancreatitis-induced lung injury.
Pancreatitis
Amelioration of rat cerulein pancreatitis by guamerin-derived peptide, a novel elastase inhibitor.
Pancreatitis
An anti-coagulation agent Futhan preferentially targets GABA(A) receptors in lungepithelia: implication in treating asthma.
Pancreatitis
Anti-tryptase treatment using nafamostat mesilate has a therapeutic effect on experimental colitis.
Pancreatitis
Antimetastatic activity of a synthetic serine protease inhibitor, FOY-305 (Foypan).
Pancreatitis
Antiproteases in the treatment of acute necrotizing pancreatitis: continuous regional arterial infusion.
Pancreatitis
Antiretroviral drugs and acute pancreatitis in HIV/AIDS patients: is there any association? A literature review.
Pancreatitis
Antisecretory vs. antiproteasic drugs in the prevention of post-ERCP pancreatitis: the evidence-based medicine derived from a meta-analysis study.
Pancreatitis
Aprotinin revisited: formulation, characterization, biodistribution and therapeutic potential of new aprotinin microemulsion in acute pancreatitis.
Pancreatitis
ASSESSMENT OF THE PROTECTIVE EFFECTS OF ORAL TOCOTRIENOLS IN ARGININE CHRONIC-LIKE PANCREATITIS.
Pancreatitis
Autophagic cell death of pancreatic acinar cells in serine protease inhibitor Kazal type 3-deficient mice.
Pancreatitis
Auxiliary activation of the complement system and its importance for the pathophysiology of clinical conditions.
Pancreatitis
Beneficial effects of cholecystokinin-receptor blockade and inhibition of proteolytic enzyme activity in experimental acute hemorrhagic pancreatitis in mice. Evidence for cholecystokinin as a major factor in the development of acute pancreatitis.
Pancreatitis
Benefit of continuous regional arterial infusion of protease inhibitor and antibiotic in the management of acute necrotizing pancreatitis.
Pancreatitis
Biochemical characterization of reperfusion pancreatitis in porcine pancreatic allografts after six hours of cold storage.
Pancreatitis
Biochemical studies in peritoneal fluid from patients with acute pancreatitis. Relationship to etiology.
Pancreatitis
Can specific calcium channel blockade be the basis for a drug-based treatment of acute pancreatitis?
Pancreatitis
Case of a bleeding pseudoaneurysm of the middle colic artery complicating acute pancreatitis.
Pancreatitis
Cathepsin B Activates Human Trypsinogen 1 but Not Proelastase 2 or Procarboxypeptidase B.
Pancreatitis
Cathepsin B Activity Initiates Apoptosis via Digestive Protease Activation in Pancreatic Acinar Cells and Experimental Pancreatitis.
Pancreatitis
Cathepsin B regulates the intrinsic angiogenic threshold of endothelial cells.
Pancreatitis
Cathepsin D regulates cathepsin B activation and disease severity predominantly in inflammatory cells during experimental pancreatitis.
Pancreatitis
Chronic hereditary pancreatitis in a girl with a serine protease inhibitor kazal type I (SPINK-1) gene mutation and a coxsackie type B5 infection.
Pancreatitis
Chronic pancreatitis associated with the p.G208A variant of PRSS1 gene in a European patient.
Pancreatitis
Chymotrypsin Reduces the Severity of Secretagogue-Induced Pancreatitis in Mice.
Pancreatitis
Clinical profile of acute pancreatitis following treatment with protease inhibitors: a real-world analysis of post-marketing surveillance data.
Pancreatitis
Clinical trial with a protease inhibitor gabexate mesilate in acute pancreatitis.
Pancreatitis
Combined therapy of a cephalosporin, Shiomarin and a new potent protease inhibitor, E3123 in rat taurocholate-induced pancreatitis.
Pancreatitis
Combined treatment with C1 esterase inhibitor and antithrombin III improves survival in severe acute experimental pancreatitis.
Pancreatitis
Comparative study of protease inhibitors on coagulation abnormalities in canine pancreatitis.
Pancreatitis
Comparison of the efficacy of continuous i.v. infusion versus continuous regional arterial infusion of nafamostat mesylate for severe acute pancreatitis.
Pancreatitis
Compatibility of carbapenem antibiotics with nafamostat mesilate in arterial infusion therapy for severe acute pancreatitis: stabilities of carbapenem antibiotics.
Pancreatitis
Completion Pancreaticoduodenectomy for Hereditary Pancreatitis After Prior Puestow Procedure: A Case Report.
Pancreatitis
Connections Between Genetics and Clinical Data: Role of MCP-1, CFTR, and SPINK-1 in the Setting of Acute, Acute Recurrent, and Chronic Pancreatitis.
Pancreatitis
Continuous arterial infusion of protease inhibitor for severe acute pancreatitis.
Pancreatitis
Continuous arterial infusion therapy for severe acute pancreatitis: correlation between CT arteriography and therapeutic effect.
Pancreatitis
Continuous intraarterial infusion of protease inhibitors in acute pancreatitis.
Pancreatitis
Continuous regional application of protease inhibitor in the treatment of acute pancreatitis. An experimental study using closed duodenal obstruction model in dogs.
Pancreatitis
Continuous regional arterial infusion (CRAI) therapy reduces the mortality rate of acute necrotizing pancreatitis: results of a cooperative survey in Japan.
Pancreatitis
Continuous regional arterial infusion effective for children with acute necrotizing pancreatitis even under neutropenia.
Pancreatitis
Continuous regional arterial infusion for acute pancreatitis: a propensity score analysis using a nationwide administrative database.
Pancreatitis
Continuous regional arterial infusion of protease inhibitor and antibiotics in acute necrotizing pancreatitis.
Pancreatitis
Continuous Regional Arterial Infusion of Protease Inhibitors for Treatment of Severe Acute Pancreatitis: Systematic Review and Meta-Analysis.
Pancreatitis
Continuous Regional Arterial Infusion of Protease Inhibitors Has No Efficacy in the Treatment of Severe Acute Pancreatitis: A Retrospective Multicenter Cohort Study.
Pancreatitis
Continuous regional arterial infusion therapy for acute necrotizing pancreatitis due to Mycoplasma pneumoniae infection in a child.
Pancreatitis
Continuous regional arterial infusion versus intravenous administration of the protease inhibitor nafamostat mesilate for predicted severe acute pancreatitis: a multicenter, randomized, open-label, phase 2 trial.
Pancreatitis
Controlled trial of protease inhibitor gabexelate mesilate (FOY) in the treatment of acute pancreatitis.
Pancreatitis
Correlation among complement activation, protease inhibitors, and clinical course in acute pancreatitis in man.
Pancreatitis
Cytokine expressions of spinal cord injury treated by neurotropin and nafamostat mesylate.
Pancreatitis
Cytoprotective effects of prostaglandins and a new potent protease inhibitor in acute pancreatitis.
Pancreatitis
Defective binding of SPINK1 variants is an uncommon mechanism for impaired trypsin inhibition in chronic pancreatitis.
Pancreatitis
Deficiency of cathepsin C ameliorates severity of acute pancreatitis by reduction of neutrophil elastase activation and cleavage of E-cadherin.
Pancreatitis
Design and screening of ASIC inhibitors based on aromatic diamidines for combating neurological disorders.
Pancreatitis
Detection and measurement of canine alpha-macroglobulins by enzyme immuno-assay.
Pancreatitis
Digestive enzymes and protease inhibitors in plasma from patients with acute pancreatitis.
Pancreatitis
Distribution of a synthetic protease inhibitor in rat pancreatic acini after supramaximal secretagogue stimulation.
Pancreatitis
Distribution of protease inhibitors in lipid emulsions: gabexate mesilate and camostat mesilate.
Pancreatitis
Drug-Induced lipid changes: a review of the unintended effects of some commonly used drugs on serum lipid levels.
Pancreatitis
E-3123, a new synthetic protease inhibitor, protects against deoxycholic acid-induced acute pancreatitis in dogs.
Pancreatitis
Early trypsin activation develops independently of autophagy in caerulein-induced pancreatitis in mice.
Pancreatitis
Effect of a new synthetic protease inhibitor on beta-endorphin release during acute pancreatitis in dogs.
Pancreatitis
Effect of a synthetic protease inhibitor (Fut-175) on coagulation abnormalities during experimental acute pancreatitis in dogs.
Pancreatitis
Effect of camostate administration for two weeks on experimental pancreatitis in mice and rats.
Pancreatitis
Effect of continuous arterial infusion of protease inhibitor on experimental acute pancreatitis.
Pancreatitis
Effect of different immunosuppressive agents on acute pancreatitis: a comparative study in an improved animal model.
Pancreatitis
Effect of ligands that increase cAMP on caerulein-induced zymogen activation in pancreatic acini.
Pancreatitis
Effect of magnesium supplementation and depletion on the onset and course of acute experimental pancreatitis.
Pancreatitis
Effect of oral administration of AZD8309, a CXCR2 antagonist, on the severity of experimental pancreatitis.
Pancreatitis
Effect of T-0632, a cholecystokininA receptor antagonist, on experimental acute pancreatitis.
Pancreatitis
Effect of the oral administration of sepimostat mesilate on cerulein induced acute pancreatitis in rats.
Pancreatitis
Effect of ultrasonic nebulization of Miraclid on the proteolytic activity in tracheobronchial secretions of rats.
Pancreatitis
Effects of a newly synthesized pancreatic protease inhibitor (PATM) on pancreatic microcirculation in experimental acute pancreatitis.
Pancreatitis
Effects of acute pancreatitis on hepatic secretion of lysosomal enzymes into bile and hepatic lysosomal fragility: protective effects of a new synthetic protease inhibitor, ONO 3307.
Pancreatitis
Effects of nafamostat mesilate on the prevention of cerulein-induced acute pancreatitis.
Pancreatitis
Effects of protease inhibitor pretreatment on hemodynamic performances and survival rate in experimental, acute pancreatitis.
Pancreatitis
Effects of protease inhibitors on coagulation abnormalities in acute canine pancreatitis.
Pancreatitis
Effects of serine protease inhibitors on accumulation of polymorphonuclear leukocytes in the lung induced by acute pancreatitis in rats.
Pancreatitis
Efficacy of continuous regional arterial infusion of a protease inhibitor and antibiotic for severe acute pancreatitis in patients admitted to an intensive care unit.
Pancreatitis
Endoscopic lithotomy of common bile duct stones with sublingual nitroglycerin and guidewire.
Pancreatitis
Endothelin receptor blockade in severe acute pancreatitis leads to systemic enhancement of microcirculation, stabilization of capillary permeability, and improved survival rates.
Pancreatitis
Ethanol enhances carbachol-induced protease activation and accelerates Ca2+ waves in isolated rat pancreatic Acini.
Pancreatitis
Evidence for altered cellular calcium in the pathogenetic mechanism of acute pancreatitis in rats.
Pancreatitis
Evidence for extraluminal trypsinogen activation in three different models of acute pancreatitis.
Pancreatitis
Extracellular cleavage of E-cadherin by leukocyte elastase during acute experimental pancreatitis in rats.
Pancreatitis
Fluorescent diphenylphosphonate-based probes for detection of serine protease activity during inflammation.
Pancreatitis
Gabexate mesilate improves pancreatic microcirculation and reduces lung edema in a rat model of acute pancreatitis.
Pancreatitis
Gabexate mesilate in human acute pancreatitis. German Pancreatitis Study Group.
Pancreatitis
Gabexate mesilate suppresses influenza pneumonia in mice through inhibition of cytokines.
Pancreatitis
Gabexate mesilate vs aprotinin in human acute pancreatitis (GA.ME.P.A.). A prospective, randomized, double-blind multicenter study.
Pancreatitis
Gabexate mesilate, a synthetic protease inhibitor, attenuates carbon tetrachloride-induced liver injury in rats.
Pancreatitis
Genetic Abnormalities in Pancreatitis: An Update on Diagnosis, Clinical Features, and Treatment.
Pancreatitis
Genetic background is different between sentinel and recurrent acute pancreatitis.
Pancreatitis
Genetic, epidemiological, and clinical aspects of hereditary pancreatitis: a population-based cohort study in Denmark.
Pancreatitis
Granulocyte elastase in assessment of severity of acute pancreatitis. Comparison with acute-phase proteins C-reactive protein, alpha 1-antitrypsin, and protease inhibitor alpha 2-macroglobulin.
Pancreatitis
High Incidence of PRSS1 and SPINK1 Mutations in Korean Children With Acute Recurrent and Chronic Pancreatitis.
Pancreatitis
High prevalence of the c.74A>C SPINK1 variant in miniature and standard Schnauzers.
Pancreatitis
Histone Deacetylase Regulates Trypsin Activation, Inflammation, and Tissue Damage in Acute Pancreatitis in Mice.
Pancreatitis
Human urinary trypsin inhibitor, urinastatin, prevents pancreatic injuries induced by pancreaticobiliary duct obstruction with cerulein stimulation and systemic hypotension in the rat.
Pancreatitis
Hyperlipidemia associated with HIV protease inhibitor use: pathophysiology, prevalence, risk factors and treatment.
Pancreatitis
Identification of CFTR, PRSS1, and SPINK1 mutations in 381 patients with pancreatitis.
Pancreatitis
Identification of impurities in nafamostat mesylate using HPLC-IT-TOF/MS: A series of double-charged ions.
Pancreatitis
Identification of nafamostat mesilate as an inhibitor of the fat mass and obesity-associated protein (FTO) demethylase activity.
Pancreatitis
Identification of variants of the SPINK1 gene and their association with pancreatitis in Miniature Schnauzers.
Pancreatitis
Impact of continuous regional arterial infusion in the treatment of acute necrotizing pancreatitis: analysis of a national administrative database.
Pancreatitis
Impaired hepatic energy metabolism in rat acute pancreatitis: protective effects of prostaglandin E2 and synthetic protease inhibitor ONO 3307.
Pancreatitis
Improved survival in mice with diet-induced pancreatitis treated with new potent protease inhibitor, E-3123 and a broad spectrum antibiotic, cefmetazole.
Pancreatitis
In vivo imaging with fluorescent smart probes to assess treatment strategies for acute pancreatitis.
Pancreatitis
Inactivation of mesotrypsin by chymotrypsin C prevents trypsin inhibitor degradation.
Pancreatitis
Incidence, Prevalence, Etiology, and Prognosis of First-Time Chronic Pancreatitis in Young Patients: A Nationwide Cohort Study.
Pancreatitis
Influence of the CCK-antagonist loxiglumide on bile-induced experimental pancreatitis.
Pancreatitis
Inhibition of prostasin secretion by serine protease inhibitors in the kidney.
Pancreatitis
Inhibitory effects of native and synthetic protease inhibitors on plasma proteases in acute pancreatitis.
Pancreatitis
Interstitial protease activation is the central event in progression to necrotizing pancreatitis.
Pancreatitis
Intestinal microcirculation and gut permeability in acute pancreatitis: early changes and therapeutic implications.
Pancreatitis
Intracellular action of an exogenous low-molecular-weight synthetic protease inhibitor, E3123, in cerulein-induced acute pancreatitis in rats.
Pancreatitis
Intrapancreatic zymogen activation and levels of ATP and glutathione during caerulein pancreatitis in rats.
Pancreatitis
Is High-Dose Nafamostat Mesilate Effective for the Prevention of Post-ERCP Pancreatitis, Especially in High-Risk Patients?
Pancreatitis
Is the SPINK1 variant p.N34S overrepresented in patients with acute pancreatitis?
Pancreatitis
Japanese guidelines for the management of acute pancreatitis: Japanese Guidelines 2015.
Pancreatitis
JPN Guidelines for the management of acute pancreatitis: medical management of acute pancreatitis.
Pancreatitis
Levels of leukocyte proteases in plasma and peritoneal exudate in severe, acute pancreatitis.
Pancreatitis
Levels of total alpha-macroglobulin and trypsin-like immunoreactivity are poor indicators of clinical severity in spontaneous canine acute pancreatitis.
Pancreatitis
Ligation-induced acute pancreatitis increases pancreatic circulating trypsinogen activation peptides.
Pancreatitis
Long-term effects of nafamostat and imipenem on experimental acute pancreatitis in rats.
Pancreatitis
Loss of chymotrypsin-like protease (CTRL) alters intrapancreatic protease activation but not pancreatitis severity in mice.
Pancreatitis
Making sense of meta-analyses on the use of protease inhibitors for the prevention of post-ERCP pancreatitis.
Pancreatitis
Matrix metalloproteinase-9 derived from polymorphonuclear neutrophils increases gut barrier dysfunction and bacterial translocation in rat severe acute pancreatitis.
Pancreatitis
Mechanism of kinin release during experimental acute pancreatitis in rats: evidence for pro- as well as anti-inflammatory roles of oedema formation.
Pancreatitis
Missorting of cathepsin B into the secretory compartment of CI-MPR/IGFII-deficient mice does not induce spontaneous trypsinogen activation but leads to enhanced trypsin activity during experimental pancreatitis--without affecting disease severity.
Pancreatitis
MMP-9 in serum correlates with the development of pulmonary complications in experimental acute pancreatitis.
Pancreatitis
Molecular dynamics simulations reveal structural instability of human trypsin inhibitor upon D50E and Y54H mutations.
Pancreatitis
Monitoring of serum proteinase--antiproteinase balance and systemic inflammatory response in prognostic evaluation of acute pancreatitis. Results of a prospective multicenter study.
Pancreatitis
Multifactorial Genesis of Pancreatitis in Primary Hyperparathyroidism: Evidence for "Protective" (PRSS2) and "Destructive" (CTRC) Genetic Factors.
Pancreatitis
Mutations in the cationic trypsinogen gene are associated with recurrent acute and chronic pancreatitis.
Pancreatitis
Mutations in the serine protease inhibitor Kazal Type 1 (SPINK1) gene in Japanese patients with pancreatitis.
Pancreatitis
Nafamostat and sepimostat identified as novel neuroprotective agents via NR2B N-methyl-D-aspartate receptor antagonism using a rat retinal excitotoxicity model.
Pancreatitis
Nafamostat for Prophylaxis against Post-Endoscopic Retrograde Cholangiopancreatography Pancreatitis Compared with Gabexate.
Pancreatitis
Nafamostat mesilate attenuates inflammation and apoptosis and promotes locomotor recovery after spinal cord injury.
Pancreatitis
Nafamostat mesilate attenuates transient focal ischemia/reperfusion-induced brain injury via the inhibition of endoplasmic reticulum stress.
Pancreatitis
Nafamostat mesilate for prevention of post-endoscopic retrograde cholangiopancreatography pancreatitis: a prospective, randomized, double-blind, controlled trial.
Pancreatitis
Nafamostat Mesilate Improves Function Recovery after Stroke by Inhibiting Neuroinflammation in Rats.
Pancreatitis
Nafamostat mesilate, a noncalcium compound, as an anticoagulant, induces calcium-dependent haemolysis when infused with packed erythrocytes.
Pancreatitis
Nafamostat mesilate, a serine protease inhibitor, suppresses lipopolysaccharide-induced nitric oxide synthesis and apoptosis in cultured human trophoblasts.
Pancreatitis
Nelfinavir/ritonavir reduces acinar injury but not inflammation during mouse caerulein pancreatitis.
Pancreatitis
New strategy for acute necrotizing pancreatitis: Continuous Regional Arterial Infusion (CRAI) therapy.
Pancreatitis
Obstructive pancreatitis secondary to a pancreatic metastasis from lung cancer treated with nasopancreatic drainage.
Pancreatitis
Pancreatic lysosomal thiol proteinases and inhibitors in acute pancreatitis induced in rats.
Pancreatitis
Pancreatic protease activation by alcohol metabolite depends on Ca2+ release via acid store IP3 receptors.
Pancreatitis
Pancreatic secretory proteins in sera from rats before and after induction of experimental pancreatitis.
Pancreatitis
Pancreatitis risk in primary hyperparathyroidism: relation to mutations in the SPINK1 trypsin inhibitor (N34S) and the cystic fibrosis gene.
Pancreatitis
para-Sulphonato-calix[n]arene capped silver nanoparticles challenge the catalytic efficiency and the stability of a novel human gut serine protease inhibitor.
Pancreatitis
Peritoneal lavage with aprotinin in patients with severe acute pancreatitis. Effects on plasma and peritoneal levels of trypsin and leukocyte proteases and their major inhibitors.
Pancreatitis
Pharmacologic prophylaxis of post-endoscopic retrograde cholangiopancreatography pancreatitis: protease inhibitors and NSAIDs in a meta-analysis.
Pancreatitis
Pharmacological studies of 6-amidino-2-naphthyl 4-[(4,5-dihydro-1H-imidazol-2-yl)amino]benzoate dimethanesulfonate. Effects on experimental pancreatitis.
Pancreatitis
Pharmacological studies of FUT-175, nafamostat mesilate. V. Effects on the pancreatic enzymes and experimental acute pancreatitis in rats.
Pancreatitis
Plasma alpha 2-macroglobulin-trypsin complexlike substance (MTLS) in pancreatic disease.
Pancreatitis
Plasmapheresis in the treatment of an acute pancreatitis due to protease inhibitor-induced hypertriglyceridemia.
Pancreatitis
Pre-Study protocol MagPEP: a multicentre randomized controlled trial of magnesium sulphate in the prevention of post-ERCP pancreatitis.
Pancreatitis
Prevention of the spread of experimental acute pancreatitis by intraductal administration of a synthetic protease inhibitor in dogs.
Pancreatitis
Protease activation during in vivo pancreatitis is dependent on calcineurin activation.
Pancreatitis
Protease Activation during in vivo Pancreatitis is Dependent upon Calcineurin Activation.
Pancreatitis
Protease Activation, Pancreatic Leakage, and Inflammation in Acute Pancreatitis: Differences between Mild and Severe Cases and Changes over the First Three Days.
Pancreatitis
Protease inhibitors for prevention of ERCP pancreatitis: can we afford the price of success?
Pancreatitis
Protease inhibitors in acute human pancreatitis. Correlation between biochemical changes and clinical course.
Pancreatitis
Protease inhibitors in acute pancreatitis: lessons from the bench and failed clinical trials.
Pancreatitis
Protease inhibitors, inflammatory markers, and their association with outcome in dogs with naturally occurring acute pancreatitis.
Pancreatitis
Protease Inhibitors: Candidate Drugs to Inhibit Severe Acute Respiratory Syndrome Coronavirus 2 Replication.
Pancreatitis
Protease-antiprotease imbalance, hemodynamic and regional blood flow changes in experimental pancreatitis.
Pancreatitis
Protease-Sensitive Pancreatic Lipase Variants Are Associated With Early Onset Chronic Pancreatitis.
Pancreatitis
Proteases and protease inhibitors in cerulein-induced acute pancreatitis in rats.
Pancreatitis
Proteases and protease inhibitors in taurocholate-induced acute pancreatitis in rats.
Pancreatitis
Protection by a new synthetic protease inhibitor, ONO3307, of the rat exocrine pancreas during acute edematous pancreatitis induced by a supramaximal dose of caerulein in comparison with FOY007.
Pancreatitis
Protection by gabexate mesilate (FOY) of the exocrine pancreas in rats with acute pancreatitis induced by a supramaximal dose of caerulein.
Pancreatitis
Protective effect of a cephalosporin, Shiomarin, plus a new potent protease inhibitor, E3123, on rat taurocholate-induced pancreatitis.
Pancreatitis
Protective effect of nafamostat mesilate on cellular and lysosomal fragility of acinar cells in rat cerulein pancreatitis.
Pancreatitis
Protective effects of a prostaglandin E1 oligomer on taurocholate-induced rat pancreatitis.
Pancreatitis
Protective effects of combined therapy with a protease inhibitor, ONO 3307, and a xanthine oxidase inhibitor, allopurinol on temporary ischaemic model of pancreatitis in rats.
Pancreatitis
Protective effects of prophylaxis with a protease inhibitor and a free radical scavenger against a temporary ischemia model of pancreatitis.
Pancreatitis
Protective effects of therapy with a protease and xanthine oxidase inhibitor in short form pancreatic biliary obstruction and ischemia in rats.
Pancreatitis
Protective effects of urinary trypsin inhibitor on systemic inflammatory response induced by lipopolysaccharide.
Pancreatitis
Protective role of urinary trypsin inhibitor in acute lung injury induced by lipopolysaccharide.
Pancreatitis
Protective role of urinary trypsin inhibitor in lung expression of proinflammatory cytokines accompanied by lethal liver injury in mice.
Pancreatitis
PROTEOLYTIC ENZYMES : II. THE PHYSIOLOGICAL SIGNIFICANCE OF THE CONTROL OF THEIR ACTIVITY, ESPECIALLY WITH RESPECT TO BACTERIAL GROWTH.
Pancreatitis
PRSS1 and SPINK1 mutations in idiopathic chronic and recurrent acute pancreatitis.
Pancreatitis
Randomized, placebo-controlled trial of lazaroid effects on severe acute pancreatitis in rats.
Pancreatitis
Rat experimental model of continuous regional arterial infusion of protease inhibitor and its effects on severe acute pancreatitis.
Pancreatitis
Recurrent idiopathic pancreatitis in familial adenomatous polyposis: report of a case-series and review of the literature.
Pancreatitis
Reducing extracellular pH sensitizes the acinar cell to secretagogue-induced pancreatitis responses in rats.
Pancreatitis
Regional effects of nafamostat, a novel potent protease and complement inhibitor, on severe necrotizing pancreatitis.
Pancreatitis
Renal function in experimentally induced acute pancreatitis in dogs: how it is affected by the nephrotoxic substance in pancreatic exudate from ascitic fluid.
Pancreatitis
Risk for post-ERCP pancreatitis after needle knife precut sphincterotomy following repeated cannulation attempts.
Pancreatitis
Role of early continuous regional arterial infusion of protease inhibitor and antibiotic in nonsurgical treatment of acute necrotizing pancreatitis.
Pancreatitis
Role of Intrapancreatic SPINK1/Spink3 Expression in the Development of Pancreatitis.
Pancreatitis
Role of Ulinastatin, a trypsin inhibitor, in severe acute pancreatitis in critical care setting: A retrospective analysis.
Pancreatitis
Selected biochemical parameters and ultrastructural picture of pancreas due to Ulinastatin treatment of experimental acute pancreatitis.
Pancreatitis
Serine Protease Inhibitor Kazal Type 1 (SPINK1) c.194+2T > C Mutation May Predict Long-term Outcome of Endoscopic Treatments in Idiopathic Chronic Pancreatitis.
Pancreatitis
Serum interleukin-6 and interleukin-10 in patients with acute pancreatitis: clinical implications.
Pancreatitis
Serum protease inhibitor capacity for elastase and the severity of pancreatitis.
Pancreatitis
Site-specific therapeutic effects of protease inhibitors: effect of route of administration in experimental pancreatitis.
Pancreatitis
Sodium taurocholate-induced acute pancreatitis in pigs. Pathomorphological studies of the pancreas in untreated animals and animals pretreated with high doses of corticosteroids or protease inhibitors.
Pancreatitis
SPINK1 N34S is strongly associated with recurrent acute pancreatitis but is not a risk factor for the first or sentinel acute pancreatitis event.
Pancreatitis
SPINK1/PSTI mutations are associated with tropical pancreatitis in Bangladesh. A preliminary report.
Pancreatitis
Stability of gabexate mesilate products: Influence of the addition of mannitol.
Pancreatitis
Status of use of protease inhibitors for the prevention and treatment of pancreatitis after endoscopic retrograde cholangiopancreatography: An epidemiologic analysis of the evidence-practice gap using a health insurance claims database.
Pancreatitis
Studies on the role of the plasma protease inhibitors on in vitro C3 activation and in acute pancreatitis.
Pancreatitis
Successful management of severe L-asparaginase-associated pancreatitis by continuous regional arterial infusion of protease inhibitor and antibiotic.
Pancreatitis
Successful treatment of severe acute pancreatitis by the combination therapy of continuous arterial infusion of a protease inhibitor and continuous hemofiltration.
Pancreatitis
Suppressive effect of camostat mesilate (FOY 305) on acute experimental allergic encephalomyelitis (EAE).
Pancreatitis
Surgical anatomy of arteries running transversely in the pancreas, with special reference to the superior transverse pancreatic artery.
Pancreatitis
Synthetic versus natural protease inhibitors in acute experimental pancreatitis.
Pancreatitis
The effect of gabexate mesilate on pancreatic and hepatic microcirculation in acute experimental pancreatitis in rats.
Pancreatitis
The mechanism of conversion of xanthine dehydrogenase to xanthine oxidase in acute pancreatitis in the canine isolated pancreas preparation.
Pancreatitis
The Molecular Aspect of Antitumor Effects of Protease Inhibitor Nafamostat Mesylate and Its Role in Potential Clinical Applications.
Pancreatitis
The pH modulator chloroquine blocks trypsinogen activation peptide generation in cerulein-induced pancreatitis.
Pancreatitis
The Prevalence and Characteristics of Genetic Pancreatitis in Children with Chronic and Recurrent Acute Pancreatitis.
Pancreatitis
The proteome of mesenteric lymph during acute pancreatitis and implications for treatment.
Pancreatitis
The Results of Severe Acute Pancreatitis Treatment With Continuous Regional Arterial Infusion of Protease Inhibitor and Antibiotic: A Randomized Controlled Study.
Pancreatitis
The role of intracellular calcium signaling in premature protease activation and the onset of pancreatitis.
Pancreatitis
The therapeutic effect of a new synthetic protease inhibitor (E-3123) on hemodynamic changes during experimental acute pancreatitis in dogs.
Pancreatitis
The use of protease inhibitors during acute haemorrhagic pancreatitis. Experimental findings and clinical implications.
Pancreatitis
Therapeutic effect of ultrasound interventional perirenal catheter-assisted early peripancreatic lavage of protease inhibitor on severe acute pancreatitis in miniature pigs.
Pancreatitis
Therapeutic effects of ulinastatin on experimental crescentic glomerulonephritis in rats.
Pancreatitis
Therapeutic efficacy of continuous arterial infusion of an antibiotic and a protease inhibitor via the superior mesenteric artery for acute pancreatitis in an animal model.
Pancreatitis
Therapeutic regimens in acute experimental pancreatitis in rats: effects of a protease inhibitor, a beta-agonist, and antibiotics.
Pancreatitis
Treatment of acute pancreatitis with protease inhibitors administered through intravenous infusion: an updated systematic review and meta-analysis.
Pancreatitis
Treatment with ginkgo biloba extract protects rats against acute pancreatitis-associated lung injury by modulating alveolar macrophage.
Pancreatitis
Trypsinogen stabilization by mutation Arg117-->His: a unifying pathomechanism for hereditary pancreatitis?
Pancreatitis
Tumour necrosis factor ? secretion induces protease activation and acinar cell necrosis in acute experimental pancreatitis in mice.
Pancreatitis
Ulinastatin attenuates LPS-induced inflammation in mouse macrophage RAW264.7 cells by inhibiting the JNK/NF-?B signaling pathway and activating the PI3K/Akt/Nrf2 pathway.
Pancreatitis
Ulinastatin Exerts Synergistic Effects with Taxotere and Inhibits Invasion and Metastasis of Breast Cancer by Blocking Angiogenesis and the Epithelial-Mesenchymal Transition.
Pancreatitis
Ulinastatin for pancreatitis after endoscopic retrograde cholangiopancreatography: a randomized, controlled trial.
Pancreatitis
Ulinastatin Protects against CVB3-Induced Acute Viral Myocarditis through Nrf2 Activation.
Pancreatitis
Ulinastatin Protects Against LPS-Induced Acute Lung Injury by Attenuating TLR4/NF-?B Pathway Activation and Reducing Inflammatory Mediators.
Pancreatitis
Ulinastatin shows preventive effect on post-endoscopic retrograde cholangiopancreatography pancreatitis in a multicenter prospective randomized study.
Pancreatitis
Urinary trypsin inhibitor as a therapeutic option for endotoxin-related inflammatory disorders.
Pancreatitis
Urinary trypsin inhibitor protects against liver injury and coagulation pathway dysregulation induced by lipopolysaccharide/D-galactosamine in mice.
Pancreatitis
Urinary trypsin inhibitor protects against systemic inflammation induced by lipopolysaccharide.
Pancreatitis
Urinary trypsin inhibitor reduces inflammatory response in kidney induced by lipopolysaccharide.
Pancreatitis
Urinary trypsin inhibitor suppresses surgical stress-facilitated lung metastasis of murine colon 26-L5 carcinoma cells.
Pancreatitis
Use of a synthetic protease inhibitor for the treatment of L-asparaginase-induced acute pancreatitis complicated by disseminated intravascular coagulation.
Pancreatitis
Utility of the new Japanese severity score and indications for special therapies in acute pancreatitis.
Pancreatitis
Vascular access system for continuous arterial infusion of a protease inhibitor in acute necrotizing pancreatitis.
Pancreatitis
[A 50-year history of new drugs in Japan-the development and trends of hemostatics and antithrombotic drugs]
Pancreatitis
[A case of severe acute pancreatitis successfully treated by continuous arterial infusion of a protease inhibitor]
Pancreatitis
[Acute Pancreatitis after Thoracoabdominal Aortic Aneurysm Repair in Patient Having a History of Pancreaticoduodenectomy;Report of a Case].
Pancreatitis
[Acute pancreatitis: biochemical markers and pathogenical approaches to the treatment using protease inhibitors]
Pancreatitis
[Apropos of the immediate prognosis of acute pancreatitis treated with protease inhibitors.]
Pancreatitis
[Changes of acinar cells in the pancreato-biliary duct ligation with exocrine pancreatic stimulation model in rats; protective effects of a new potent protease inhibitor, ONO3307]
Pancreatitis
[Classification of acute pancreatitis in correlation with serum protease levels]
Pancreatitis
[Clinical experiences with the new protease inhibitor Contrybal. Current status of combined therapy of pancreatitis]
Pancreatitis
[Continuous arterial infusion of protease inhibitor with supplementary therapy for the patients with severe acute pancreatitis--clinical effect of arterial injection of ulinastatin]
Pancreatitis
[Continuous regional arterial infusion of protease inhibitor and antibiotic for severe acute pancreatitis]
Pancreatitis
[Could nafamostat or gabexate prevent the post endoscopic retrograde cholangiopancreatography pancreatitis?].
Pancreatitis
[Effect of continuous arterial infusion of protease inhibitor on experimental acute pancreatitis induced by closed duodenal loop obstruction]
Pancreatitis
[Effect of protease inhibitors on the activity of trypsin and lipase in the pancreas and blood serum of rats in acute pancreatitis]
Pancreatitis
[Effect of the endolymphatic administration of protease inhibitors on pancreatic morphofunctional activity in acute experimental pancreatitis]
Pancreatitis
[Effects of E-3123, a new protease inhibitor, on several protease activities and on experimental acute pancreatitis]
Pancreatitis
[Flow cytometry detection of erythrocyte antigens and antibodies. Technical aspects and new clinical applications]
Pancreatitis
[Gabexate mesilate vs gabexate mesilate combined with octreotide in the prevention of postoperative complications of pancreatic surgery: preliminary results]
Pancreatitis
[Hemodynamic and microcirculatory changes in the liver in experimental acute pancreatitis of dogs]
Pancreatitis
[Lipodystrophy and lipid metabolism alterations in HIV-infected patients receiving highly active antiretroviral therapy (HAART)]
Pancreatitis
[Peridural anesthesia and intra-aortic administration of protease inhibitors and antibiotics in the combined treatment of acute biliary pancreatitis]
Pancreatitis
[Pharmacodynamics of therapeutic agents for pancreatitis. Effect of a synthetic protease inhibitor on the serum alpha1-antitrypsin and alpha2-macroglobulin levels]
Pancreatitis
[Pharmacokinetics studies of nafamostat mesilate (FUT), a synthetic protease inhibitor, which has been used for the treatments of DIC and acute pancreatitis, and as an anticoagulant in extracorporeal circulation]
Pancreatitis
[Protease inhibitors as immunomodulators in experimental acute pancreatitis and staphylococcal infection]
Pancreatitis
[Remote future of lesions of acute pancreatitis treated by protease inhibitors.]
Pancreatitis
[Renal microcirculation in experimental acute pancreatitis of dogs--the effect of pancreatic protease inhibitor and dopamine]
Pancreatitis
[SPINK1 N34S mutation as a possible cause of chronic pancreatitis in a patient with familial background]
Pancreatitis
[Study of activated pancreatic protease in experimental caerulein-induced pancreatitis]
Pancreatitis
[The level of protease inhibitors in experimental acute pancreatitis and after glucagon administration (author's transl)]
Pancreatitis
[The protease inhibitor gabexate mesilate in experimentally-induced acute pancreatitis with early gram-negative infection in the Göttingen minipig: therapeutic efficacy and effects on blood coagulation and fibrinolysis]
Pancreatitis
[Therapy of acute pancreatitis with a synthetic protease and phospholipase A2 inhibitor gabexate mesilate]
Pancreatitis
[Transduodenal electrophoresis of protease inhibitors in the treatment of acute pancreatitis]
Pancreatitis
[Treatment of acute pancreatitis with protease inhibitor, H2 receptor antagonist and somatostatin analogue]
Pancreatitis
[Ways of reducing the main postoperative complications of gastrectomy in patients with gastric cancer]
Pancreatitis, Acute Hemorrhagic
Beneficial effects of cholecystokinin-receptor blockade and inhibition of proteolytic enzyme activity in experimental acute hemorrhagic pancreatitis in mice. Evidence for cholecystokinin as a major factor in the development of acute pancreatitis.
Pancreatitis, Acute Hemorrhagic
Effect of protease inhibitor FUT-175 on acute hemorrhagic pancreatitis in mice.
Pancreatitis, Acute Hemorrhagic
Protease inhibitors and experimental acute hemorrhagic pancreatitis.
Pancreatitis, Acute Hemorrhagic
Therapeutic regimens in acute experimental hemorrhagic pancreatitis. Effects of hydration, oxygenation, peritoneal lavage, and a potent protease inhibitor.
Pancreatitis, Acute Necrotizing
Active residues and viral substrate cleavage sites of the protease of the birnavirus infectious pancreatic necrosis virus.
Pancreatitis, Acute Necrotizing
Benefit of continuous regional arterial infusion of protease inhibitor and antibiotic in the management of acute necrotizing pancreatitis.
Pancreatitis, Acute Necrotizing
Continuous regional arterial infusion (CRAI) therapy reduces the mortality rate of acute necrotizing pancreatitis: results of a cooperative survey in Japan.
Pancreatitis, Acute Necrotizing
Continuous regional arterial infusion of protease inhibitor and antibiotics in acute necrotizing pancreatitis.
Pancreatitis, Acute Necrotizing
Continuous Regional Arterial Infusion of Protease Inhibitors for Treatment of Severe Acute Pancreatitis: Systematic Review and Meta-Analysis.
Pancreatitis, Acute Necrotizing
Continuous Regional Arterial Infusion of Protease Inhibitors Has No Efficacy in the Treatment of Severe Acute Pancreatitis: A Retrospective Multicenter Cohort Study.
Pancreatitis, Acute Necrotizing
Continuous regional arterial infusion versus intravenous administration of the protease inhibitor nafamostat mesilate for predicted severe acute pancreatitis: a multicenter, randomized, open-label, phase 2 trial.
Pancreatitis, Acute Necrotizing
Crystal structure of the VP4 protease from infectious pancreatic necrosis virus reveals the acyl-enzyme complex for an intermolecular self-cleavage reaction.
Pancreatitis, Acute Necrotizing
Effect of different immunosuppressive agents on acute pancreatitis: a comparative study in an improved animal model.
Pancreatitis, Acute Necrotizing
Heparin and protease inhibitors in the prevention of experimental acute pancreatic necrosis in dogs.
Pancreatitis, Acute Necrotizing
New strategy for acute necrotizing pancreatitis: Continuous Regional Arterial Infusion (CRAI) therapy.
Pancreatitis, Acute Necrotizing
Peritoneal lavage with aprotinin in patients with severe acute pancreatitis. Effects on plasma and peritoneal levels of trypsin and leukocyte proteases and their major inhibitors.
Pancreatitis, Acute Necrotizing
Purification, crystallization and preliminary X-ray analysis of truncated and mutant forms of VP4 protease from infectious pancreatic necrosis virus.
Pancreatitis, Acute Necrotizing
Role of early continuous regional arterial infusion of protease inhibitor and antibiotic in nonsurgical treatment of acute necrotizing pancreatitis.
Pancreatitis, Acute Necrotizing
Role of Ser-652 and Lys-692 in the protease activity of infectious bursal disease virus VP4 and identification of its substrate cleavage sites.
Pancreatitis, Acute Necrotizing
Surgical anatomy of arteries running transversely in the pancreas, with special reference to the superior transverse pancreatic artery.
Pancreatitis, Acute Necrotizing
Synthesis of the infectious pancreatic necrosis virus polyprotein, detection of a virus-encoded protease, and fine structure mapping of genome segment A coding regions.
Pancreatitis, Acute Necrotizing
Vascular access system for continuous arterial infusion of a protease inhibitor in acute necrotizing pancreatitis.
Pancreatitis, Acute Necrotizing
[Effect of continuous arterial infusion of protease inhibitor on experimental acute pancreatitis induced by closed duodenal loop obstruction]
Pancreatitis, Chronic
A Hypothesized Mechanism for Chronic Pancreatitis Caused by the N34S Mutation of Serine Protease Inhibitor Kazal-Type 1 Based on Conformational Studies.
Pancreatitis, Chronic
A novel mutation of the calcium sensing receptor gene is associated with chronic pancreatitis in a family with heterozygous SPINK1 mutations.
Pancreatitis, Chronic
A phase I study of high dose camostat mesylate in healthy adults provides a rationale to repurpose the TMPRSS2 inhibitor for the treatment of COVID-19.
Pancreatitis, Chronic
Association between calcium sensing receptor gene polymorphisms and chronic pancreatitis in a US population: role of serine protease inhibitor Kazal 1type and alcohol.
Pancreatitis, Chronic
Association of rare SPINK1 gene mutation with another base substitution in chronic pancreatitis patients.
Pancreatitis, Chronic
Camostat mesilate attenuates pancreatic fibrosis via inhibition of monocytes and pancreatic stellate cells activity.
Pancreatitis, Chronic
CFTR, PRSS1 and SPINK1 mutations in the development of pancreatitis in Brazilian patients.
Pancreatitis, Chronic
CFTR, SPINK1, PRSS1, and CTRC Mutations Are Not Associated With Pancreatic Cancer in German Patients.
Pancreatitis, Chronic
Chronic pancreatitis associated with the p.G208A variant of PRSS1 gene in a European patient.
Pancreatitis, Chronic
Chymotrypsin C (CTRC) variants that diminish activity or secretion are associated with chronic pancreatitis.
Pancreatitis, Chronic
Clinical and radiological outcome of patients suffering from chronic pancreatitis associated with gene mutations.
Pancreatitis, Chronic
Completion Pancreaticoduodenectomy for Hereditary Pancreatitis After Prior Puestow Procedure: A Case Report.
Pancreatitis, Chronic
Connections Between Genetics and Clinical Data: Role of MCP-1, CFTR, and SPINK-1 in the Setting of Acute, Acute Recurrent, and Chronic Pancreatitis.
Pancreatitis, Chronic
Detection of pancreatic cancer tumours and precursor lesions by cathepsin E activity in mouse models.
Pancreatitis, Chronic
Effect of camostat mesilate on the expression of pancreatitis-associated protein (PAP), p8, and cytokines in rat spontaneous chronic pancreatitis.
Pancreatitis, Chronic
Effect of oral administration of protease inhibitor on pancreatic exocrine function in WBN/Kob rats with chronic pancreatitis.
Pancreatitis, Chronic
Effect of oral protease inhibitor administration on gallbladder motility in patients with mild chronic pancreatitis.
Pancreatitis, Chronic
Effects of synthetic serine protease inhibitors on proliferation and collagen synthesis of human pancreatic periacinar fibroblast-like cells.
Pancreatitis, Chronic
Evaluation of matrix metalloproteinase 7 in plasma and pancreatic juice as a biomarker for pancreatic cancer.
Pancreatitis, Chronic
Gene conversion between functional trypsinogen genes PRSS1 and PRSS2 associated with chronic pancreatitis in a six-year-old girl.
Pancreatitis, Chronic
High Incidence of PRSS1 and SPINK1 Mutations in Korean Children With Acute Recurrent and Chronic Pancreatitis.
Pancreatitis, Chronic
In silico prioritization and further functional characterization of SPINK1 intronic variants.
Pancreatitis, Chronic
Investigation of the SPINK1 N34S mutation in Romanian patients with alcoholic chronic pancreatitis. A clinical analysis based on the criteria of the M-ANNHEIM classification.
Pancreatitis, Chronic
Is genetic analysis helpful for diagnosing chronic pancreatitis in its early stage?
Pancreatitis, Chronic
Metastatic pancreatic adenocarcinoma associated with chronic calcific pancreatitis and a heterozygous SPINK1 N34S mutation.
Pancreatitis, Chronic
Minigene analysis of intronic variants in common SPINK1 haplotypes associated with chronic pancreatitis.
Pancreatitis, Chronic
Motion--genetic testing is useful in the diagnosis of nonhereditary pancreatic conditions: arguments for the motion.
Pancreatitis, Chronic
Mutation analysis of the cystic fibrosis transmembrane conductance regulator (CFTR) gene, the cationic trypsinogen (PRSS1) gene, and the serine protease inhibitor, Kazal type 1 (SPINK1) gene in patients with alcoholic chronic pancreatitis.
Pancreatitis, Chronic
Mutational screening of patients with nonalcoholic chronic pancreatitis: identification of further trypsinogen variants.
Pancreatitis, Chronic
Mutations in serine protease inhibitor Kazal type 1 are strongly associated with chronic pancreatitis.
Pancreatitis, Chronic
Mutations in the gene encoding the serine protease inhibitor, Kazal type 1 are associated with chronic pancreatitis.
Pancreatitis, Chronic
Mutations in the serine protease inhibitor Kazal Type 1 (SPINK1) gene in Japanese patients with pancreatitis.
Pancreatitis, Chronic
Mutations N34S and P55S of the SPINK1 gene in patients with chronic pancreatitis or pancreatic cancer and in healthy subjects: a report from Finland.
Pancreatitis, Chronic
Mutations of the serine protease inhibitor, Kazal type 1 gene, in patients with idiopathic chronic pancreatitis.
Pancreatitis, Chronic
N34S mutation in the SPINK1 gene is not associated with alternative splicing.
Pancreatitis, Chronic
Natural single-nucleotide deletion in chymotrypsinogen C gene increases severity of secretagogue-induced pancreatitis in C57BL/6 mice.
Pancreatitis, Chronic
No effect of long-term treatment with pancreatic extract on recurrent abdominal pain in patients with chronic pancreatitis.
Pancreatitis, Chronic
Novel method to rescue a lethal phenotype through integration of target gene onto the X-chromosome.
Pancreatitis, Chronic
Novel Pathogenic PRSS1 Variant p.Glu190Lys in a Case of Chronic Pancreatitis.
Pancreatitis, Chronic
Overexpression of caspase-1 (interleukin-1beta converting enzyme) in chronic pancreatitis and its participation in apoptosis and proliferation.
Pancreatitis, Chronic
Pancreatic intraepithelial neoplasia is associated with chronic pancreatitis due to serine protease inhibitor kazal type 1 and cystic fibrosis transmembrane conductance regulator mutations.
Pancreatitis, Chronic
Phenotypic variability of the homozygous IVS3+2T>C mutation in the serine protease inhibitor Kazal type 1 (SPINK1) gene in patients with chronic pancreatitis.
Pancreatitis, Chronic
Plasma alpha 2-macroglobulin-trypsin complexlike substance (MTLS) in pancreatic disease.
Pancreatitis, Chronic
Protease inhibitor therapy for recessive dystrophic epidermolysis bullosa. In vitro effect and clinical trial with camostat mesylate.
Pancreatitis, Chronic
PRSS1 and SPINK1 Mutations in Alcoholic and Idiopathic Chronic Pancreatitis.
Pancreatitis, Chronic
PRSS1 and SPINK1 mutations in idiopathic chronic and recurrent acute pancreatitis.
Pancreatitis, Chronic
Rare hereditary cause of chronic pancreatitis in a young male: SPINK1 mutation.
Pancreatitis, Chronic
Relevance of variants in serum antiproteinases for the course of chronic pancreatitis.
Pancreatitis, Chronic
Serine Protease Inhibitor Kazal Type 1 (SPINK1) c.194+2T > C Mutation May Predict Long-term Outcome of Endoscopic Treatments in Idiopathic Chronic Pancreatitis.
Pancreatitis, Chronic
SPINK1 N34S is strongly associated with recurrent acute pancreatitis but is not a risk factor for the first or sentinel acute pancreatitis event.
Pancreatitis, Chronic
Structural Basis of Covalent Inhibitory Mechanism of TMPRSS2-Related Serine Proteases by Camostat.
Pancreatitis, Chronic
The contribution of the SPINK1 c.194+2T>C mutation to the clinical course of idiopathic chronic pancreatitis in Chinese patients.
Pancreatitis, Chronic
The impact of physiological stress conditions on protein structure and trypsin inhibition of serine protease inhibitor Kazal type 1 (SPINK1) and its N34S variant.
Pancreatitis, Chronic
The NS34 mutation of serine protease inhibitor Kazal type 1 (SPINK1) gene and alcoholic chronic pancreatitis.
Pancreatitis, Chronic
The Prevalence of Cationic Trypsinogen (PRSS1) and Serine Protease Inhibitor, Kazal Type 1 (SPINK1) Gene Mutations in Polish Patients with Alcoholic and Idiopathic Chronic Pancreatitis.
Pancreatitis, Chronic
The SPINK1 N34S mutation is not associated with Type 2 diabetes mellitus in a population of the USA.
Pancreatitis, Chronic
Two novel severe mutations in the pancreatic secretory trypsin inhibitor gene (SPINK1) cause familial and/or hereditary pancreatitis.
Pancreatitis, Chronic
[Clinico-immunological changes in patients with chronic pancreatitis and their correction during the treatment]
Pancreatitis, Chronic
[Effective use of camostat mesilate for chronic disseminated intravascular coagulation complicated by thoracoabdominal aortic aneurysm]
Pancreatitis, Chronic
[Mutations of SPINK1 and PRSS1 gene in Korean patients with chronic pancreatitis]
Pancreatitis, Chronic
[Role of bioantioxidants depression and deficiency of protease inhibitor alpha 1-antitrypsin in mechanisms activating free radical oxidation and proteolysis in chronic pancreatitis]
Pancreatitis, Chronic
[SPINK1 N34S mutation as a possible cause of chronic pancreatitis in a patient with familial background]
Pancreatitis, Graft
Characterization of immunoreactive trypsin as a means of differentiating graft pancreatitis and allograft rejection after porcine pancreatic transplantation.
Pancreatitis, Graft
Graft pancreatitis and hemorrhagic cystitis. Treatment with bladder irrigation and protease inhibition.
Panniculitis
Recurrent panniculitis in a patient receiving protease inhibitor therapy for human immunodeficiency virus infection.
Panniculitis
Treatment of alpha-1-antitrypsin deficiency, massive edema, and panniculitis with alpha-1 protease inhibitor.
Panuveitis
Cicatrization of cytomegalovirus retinitis following introduction of highly active anti-retroviral therapy: uveitis as a possible indicator of good ocular prognosis.
Panuveitis
Immune recovery vitritis presenting as panuveitis following therapy with protease inhibitors.
Papilloma
Overexpression of plasminogen activator inhibitor type 2 in basal keratinocytes enhances papilloma formation in transgenic mice.
Papilloma
The interaction of smoking habit, SLPI and AnxA2 in HPV associated head and neck and other cancers.
Papilloma
[Implications of antiretroviral therapy in oral medicine--a review of literature]
Papillomavirus Infections
?-Secretase promotes membrane insertion of the human papillomavirus L2 capsid protein during virus infection.
Papillomavirus Infections
Human papillomavirus infection in head and neck cancer: The role of the secretory leukocyte protease inhibitor.
Papillomavirus Infections
Resolution of recalcitrant hand warts in an HIV-infected patient treated with potent antiretroviral therapy.
Papillomavirus Infections
Secretory Leukocyte Protease Inhibitor Expression and High-Risk HPV Infection in Anal Lesions of HIV-Positive Patients.
Papillon-Lefevre Disease
A homozygous cathepsin C mutation associated with Haim-Munk syndrome.
Papillon-Lefevre Disease
Epidermal differentiation: the role of proteases and their inhibitors.
Paralysis
Accelerated neuronal cell recovery from Botulinum neurotoxin intoxication by targeted ubiquitination.
Paralysis
Amyloid-beta deposition in the cerebral cortex in Dementia with Lewy bodies is accompanied by a relative increase in AbetaPP mRNA isoforms containing the Kunitz protease inhibitor.
Paralysis
Cell-free translation of Drosophila C virus RNA: identification of a virus protease activity involved in capsid protein synthesis and further studies on in vitro processing of cricket paralysis virus specified proteins.
Paralysis
Increased M-calpain expression in the mesencephalon of patients with Parkinson's disease but not in other neurodegenerative disorders involving the mesencephalon: a role in nerve cell death?
Paralysis
Lathyrus sativus Originating from Different Geographical Regions Reveals Striking Differences in Kunitz and Bowman-Birk Inhibitor Activities.
Paralysis
Longer-Acting and Highly-Potent Chimeric Inhibitors of Excessive Exocytosis Created with Domains from Botulinum Neurotoxin A and B.
Paralysis
Monoclonal Antibodies that Inhibit the Proteolytic Activity of Botulinum Neurotoxin Serotype/B.
Paralysis
Novel chimeras of botulinum and tetanus neurotoxins yield insights into their distinct sites of neuroparalysis.
Paralysis
Retargeting Clostridium difficile Toxin B to Neuronal Cells as a Potential Vehicle for Cytosolic Delivery of Therapeutic Biomolecules to Treat Botulism.
Paralysis
Studies on Screening, Isolation and Purification of a Fibrinolytic Protease from an Isolate (VK12) of Ganoderma Lucidum and Evaluation of its Antithrombotic Activity.
Paralysis
Targeted delivery into motor nerve terminals of inhibitors for SNARE-cleaving proteases via liposomes coupled to an atoxic botulinum neurotoxin.
Paralysis
The intracellular proteins induced by cricket paralysis virus in Drosophila cells: the effect of protease inhibitors and amino acid analogues.
Paramyxoviridae Infections
Broad spectrum antiviral activity for paramyxoviruses is modulated by biophysical properties of fusion inhibitory peptides.
Paramyxoviridae Infections
Crystals of hemagglutinin-neuraminidase of parainfluenza virus contain triple-stranded helices.
Paramyxoviridae Infections
Effects of protease inhibitors on replication of various myxoviruses.
Paramyxoviridae Infections
Proteolytic cleavage of wild type and mutants of the F protein of human parainfluenza virus type 3 by two subtilisin-like endoproteases, furin and Kex2.
Paramyxoviridae Infections
TMPRSS2 Is an Activating Protease for Respiratory Parainfluenza Viruses.
Paramyxoviridae Infections
[The pathogenetic therapy of acute respiratory diseases by aprotinin inhalations]
Paraplegia
Epidural spinal lipomatosis with acute onset of paraplegia in an HIV-positive patient treated with corticosteroids and protease inhibitor: case report.
Paraplegia
Metalloprotease-mediated OPA1 processing is modulated by the mitochondrial membrane potential.
Paraplegia
SPG7 targets the m-AAA protease complex to process MCU for uniporter assembly, Ca2+ influx, and regulation of mitochondrial permeability transition pore opening.
Paraplegia
The N-terminal domain plays a crucial role in the structure of a full-length human mitochondrial Lon protease.
Parasitic Diseases
Comparison of the separation of aziridine isomers applying heptakis(2,3-di-O-methyl-6-sulfato)beta-CD and heptakis(2,3-di-O-acetyl-6-sulfato)beta-CD in aqueous and nonaqueous systems.
Parasitic Diseases
Expression of three serine protease genes from the South East Asian malaria vector, Anopheles dirus, in relation to blood feeding and parasite infection.
Parasitic Diseases
Genes identified by an expression screen of the vector mosquito Anopheles gambiae display differential molecular immune response to malaria parasites and bacteria.
Parasitic Diseases
Growth, phenotype, and function of human intestinal mast cells are tightly regulated by transforming growth factor beta1.
Parasitic Diseases
Microbial and fungal protease inhibitors--current and potential applications.
Parasitic Diseases
Protease inhibitors and haemagglutinins associated with resistance to the protozoan parasite, Perkinsus marinus, in the Pacific oyster, Crassostrea gigas.
Parasitic Diseases
Protease inhibitors and their peptidomimetic derivatives as potential drugs.
Parasitic Diseases
Proteolytic activity in the adult and larval stages of the human roundworm parasite Angiostrongylus costaricensis.
Parasitic Diseases
Serine proteases from nematode and protozoan parasites: isolation of sequence homologs using generic molecular probes.
Paratuberculosis
A Mycobacterium avium subsp. paratuberculosis Predicted Serine Protease Is Associated with Acid Stress and Intraphagosomal Survival.
Paratuberculosis
Identification and characterization of a putative serine protease expressed in vivo by Mycobacterium avium subsp. paratuberculosis.
Paresthesia
[Implications of antiretroviral therapy in oral medicine--a review of literature]
Parkinson Disease
?-Synuclein stimulation of monoamine oxidase-B and legumain protease mediates the pathology of Parkinson's disease.
Parkinson Disease
A brain-targeted, modified neurosin (kallikrein-6) reduces ?-synuclein accumulation in a mouse model of multiple system atrophy.
Parkinson Disease
A Novel 2-DE-Based Proteomic Analysis to Identify Multiple Substrates for Specific Protease in Neuronal Cells.
Parkinson Disease
Amyloid-beta deposition in the cerebral cortex in Dementia with Lewy bodies is accompanied by a relative increase in AbetaPP mRNA isoforms containing the Kunitz protease inhibitor.
Parkinson Disease
Archaeal proteasomes effectively degrade aggregation-prone proteins and reduce cellular toxicities in mammalian cells.
Parkinson Disease
Calpastatin Gene (CAST) Is Not Associated with Late Onset Sporadic Parkinson's Disease in the Han Chinese Population.
Parkinson Disease
Cloning, expression, and purification of the general stress protein YhbO from Escherichia coli.
Parkinson Disease
Comparison of cathepsin protease activities in brain tissue from normal cases and cases with Alzheimer's disease, Lewy body dementia, Parkinson's disease and Huntington's disease.
Parkinson Disease
DJ-1 is indispensable for the S-nitrosylation of Parkin, which maintains function of mitochondria.
Parkinson Disease
Drosophila HtrA2 is dispensable for apoptosis but acts downstream of PINK1 independently from Parkin.
Parkinson Disease
Dysfunction of mitochondrial Lon protease and identification of oxidized protein in mouse brain following exposure to MPTP: Implications for Parkinson disease.
Parkinson Disease
Idebenone and resveratrol extend lifespan and improve motor function of HtrA2 knockout mice.
Parkinson Disease
Increased M-calpain expression in the mesencephalon of patients with Parkinson's disease but not in other neurodegenerative disorders involving the mesencephalon: a role in nerve cell death?
Parkinson Disease
Insulin-degrading enzyme prevents ?-synuclein fibril formation in a nonproteolytical manner.
Parkinson Disease
Lentivirus Mediated Delivery of Neurosin Promotes Clearance of Wild-type ?-Synuclein and Reduces the Pathology in an ?-Synuclein Model of LBD.
Parkinson Disease
Loss-of-function analysis suggests that Omi/HtrA2 is not an essential component of the PINK1/PARKIN pathway in vivo.
Parkinson Disease
Low CSF levels of both ?-synuclein and the ?-synuclein cleaving enzyme neurosin in patients with synucleinopathy.
Parkinson Disease
Mitochondrial serine protease HTRA2 p.G399S in a kindred with essential tremor and Parkinson disease.
Parkinson Disease
Molecular motion regulates the activity of the Mitochondrial Serine Protease HtrA2.
Parkinson Disease
Mutation analyses and association studies to assess the role of the presenilin-associated rhomboid-like gene in Parkinson's disease.
Parkinson Disease
Neural-specific deletion of Htra2 causes cerebellar neurodegeneration and defective processing of mitochondrial OPA1.
Parkinson Disease
Novel mitochondrial substrates of omi indicate a new regulatory role in neurodegenerative disorders.
Parkinson Disease
Parkinson disease protein DJ-1 converts from a zymogen to a protease by carboxyl-terminal cleavage.
Parkinson Disease
Post-treatment with the GLP-1 analogue liraglutide alleviate chronic inflammation and mitochondrial stress induced by Status epilepticus.
Parkinson Disease
Sensitive detection of caspase-3 enzymatic activities and inhibitor screening by mass spectrometry with dual maleimide labelling quantitation.
Parkinson Disease
Tensor decomposition of stimulated monocyte and macrophage gene expression profiles identifies neurodegenerative disease-specific trans-eQTLs.
Parkinson Disease
The HtrA2 Drosophila model of Parkinson's disease is suppressed by the pro-survival Bcl-2 Buffy.
Parkinson Disease
The Protease Omi Cleaves the Mitogen-Activated Protein Kinase Kinase MEK1 to Inhibit Microglial Activation.
Parkinson Disease
The yeast HtrA orthologue Ynm3 is a protease with chaperone activity that aids survival under heat stress.
Parkinson Disease
Three SNPs in the GSTO1, GSTO2 and PRSS11 genes on chromosome 10 are not associated with age-at-onset of Alzheimer's disease.
Paronychia
Dermatologic adverse effects of antiretroviral therapy: recognition and management.
Paronychia
Paronychia with pyogenic granuloma in a child treated with indinavir: the retinoid-mediated side effect theory revisited.
Paronychia
Protease inhibitor-related paronychia, ingrown toenails, desquamative cheilitis and cutaneous xerosis.
Parotitis
[Treatment of chronic recurring parotitis with the protease inhibitor aprotinin (trasylol)]
Pasteurellosis, Pneumonic
Evidence of bovine immunoglobulin G1 (IgG1) protease activity in partially purified culture supernate of Pasteurella haemolytica A1.
Pasteurellosis, Pneumonic
Novel protease produced by a Pasteurella trehalosi serotype 10 isolate from a pneumonic bighorn sheep: characteristics and potential relevance to protection.
Pemphigoid, Benign Mucous Membrane
Limbal conjunctival Langerhans cell density in ocular cicatricial pemphigoid: an indirect immunofluorescence study on Dispase-split conjunctiva.
Pemphigoid, Bullous
An immunohistochemical study of the distribution of plasminogen and plasminogen activators in bullous pemphigoid.
Pemphigoid, Bullous
Granzyme B inhibition reduces disease severity in autoimmune blistering diseases.
Pemphigoid, Bullous
Laminin in the cutaneous basement membrane as a potential target in lewisite vesication.
Pemphigoid, Bullous
[Comparison of urinary proteomics between steroid-sensitive and steroid-resistant minimal change nephrotic syndrome in children.]
Pemphigus
Effects of steroid, retinoid, and protease inhibitors on the formation of acantholysis induced in organ culture of skins from patients with benign familial chronic pemphigus.
Pemphigus
Protease inhibitors prevent plasminogen-mediated, but not pemphigus vulgaris-induced, acantholysis in human epidermis.
Pemphigus
Staphylococcal scalded skin syndrome: exfoliative toxin A (ETA) induces serine protease activity when combined with A431 cells.
Pemphigus
The protease inhibitor alpha-2-macroglobulin-like-1 is the p170 antigen recognized by paraneoplastic pemphigus autoantibodies in human.
Peptic Ulcer
Effect of pepstatin, a specific protease inhibitor, on the experimental peptic ulcers.
Peptic Ulcer
Inhibition of gastric and duodenal proteases in the treatment of haemorrhage from peptic ulcer. I. An experimental study of bentonite and other protease inhibitors.
Peptic Ulcer
[The effect of almagel, gastrotsepin and food on the acidity and protease activity of the stomach and duodenum in peptic ulcer]
Peri-Implantitis
Bacterial profiles and proteolytic activity in peri-implantitis versus healthy sites.
Perinatal Death
Lack of whey acidic protein (WAP) four-disulfide core domain protease inhibitor 2 (WFDC2) causes neonatal death from respiratory failure in mice.
Perinatal Death
[Perinatal outcomes on mortality and influencing factors among HIV-infected mothers in Sichuan province].
Periodontal Diseases
Analysis of in situ protease activity in chronic adult periodontitis patients: expression of activated MMP-2 and a 40 kDa serine protease.
Periodontal Diseases
Approaches to Understanding Mechanisms of Dentilisin Protease Complex Expression in Treponema denticola.
Periodontal Diseases
Changes of alpha1-protease inhibitor and secretory leukocyte protease inhibitor levels in gingival crevicular fluid before and after non-surgical periodontal treatment.
Periodontal Diseases
Characterization of a trypsin-like protease from the bacterium Bacteroides gingivalis isolated from human dental plaque.
Periodontal Diseases
Conservation and revised annotation of the Treponema denticola prcB-prcA-prtP locus encoding the dentilisin (CTLP) protease complex.
Periodontal Diseases
Effect of Actinobacillus actinomycetemcomitans protease on the proliferation of gingival epithelial cells.
Periodontal Diseases
Generation of lys-gingipain protease activity in Porphyromonas gingivalis W50 is independent of Arg-gingipain protease activities.
Periodontal Diseases
Generic protease detection technology for monitoring periodontal disease.
Periodontal Diseases
Molecular characterization of plasminogen activator in human supragingival plaque.
Periodontal Diseases
Molecular mechanism for the spontaneous generation of pigmentless Porphyromonas gingivalis mutants.
Periodontal Diseases
NO production in RAW264 cells stimulated with Porphyromonas gingivalis extracellular vesicles.
Periodontal Diseases
Overexpression, purification, and refolding of a Porphyromonas gingivalis cysteine protease from Escherichia coli.
Periodontal Diseases
Porphyromonas gulae lipopolysaccharide elicits inflammatory responses through toll-like receptor 2 and 4 in human gingivalis epithelial cells.
Periodontal Diseases
Protease-activated receptors and their role in IL-6 and NF-IL-6 expression in human gingival fibroblasts.
Periodontal Diseases
Proteases and their inhibitors in chronic inflammatory periodontal disease.
Periodontal Diseases
Role of salivary leukocyte protease inhibitor in periodontal disease progression.
Periodontal Diseases
Salivary and gingival crevicular fluid histatin in periodontal health and disease.
Periodontal Diseases
Sequence analysis of kgp in Porphyromonas gingivalis isolates from periodontitis patients.
Periodontal Diseases
The prpR1 and prR2 arginine-specific protease genes of Porphyromonas gingivalis W50 produce five biochemically distinct enzymes.
Periodontal Diseases
The Treponema denticola FhbB Protein Is a Dominant Early Antigen That Elicits FhbB Variant-Specific Antibodies That Block Factor H Binding and Cleavage by Dentilisin.
Periodontal Diseases
Treponema denticola dentilisin triggered TLR2/MyD88 activation upregulates a tissue destructive program involving MMPs via Sp1 in human oral cells.
Periodontal Diseases
Treponema denticola PrcB is required for expression and activity of the PrcA-PrtP (dentilisin) complex.
Periodontal Diseases
[Concentration of protease inhibitor alpha 1-antitrypsin in the blood of patients with inflammatory periodontal disease]
Periodontal Diseases
[Effect of proteases from Porphyromonas gingivalis on adhesion molecules of human periodontal ligament fibroblast cells]
Periodontal Diseases
[Protease inhibitors in gingival crevicular fluid and serum of patients with periodontal disease]
Periodontal Diseases
[Proteases and their inhibitors in rapidly progressive and in juvenile periodontitis]
Periodontal Diseases
[The relationship between periodontal disease and protease activity in gingival fluid and in saliva (author's transl)]
Periodontal Pocket
Correlations between salivary protease and supragingival or subgingival calculus index.
Periodontal Pocket
Evidence of mutualism between two periodontal pathogens: co-operative haem acquisition by the HmuY haemophore of Porphyromonas gingivalis and the cysteine protease interpain A (InpA) of Prevotella intermedia.
Periodontal Pocket
Gingival tissue human beta-defensin levels in relation to infection and inflammation.
Periodontal Pocket
[Determination of protease activity in the contents of periodontal pockets in chronic marginal periodontitis]
Periodontitis
Acute myocardial infarction elevates serine protease activity in saliva of patients with periodontitis.
Periodontitis
An in-vitro evaluation of the efficacy of garlic extract as an antimicrobial agent on periodontal pathogens: A microbiological study.
Periodontitis
Biochemical comparison of proteolytic enzymes present in rough- and smooth-surfaced capnocytophagas isolated from the subgingival plaque of periodontitis patients.
Periodontitis
Characterization of oral polymorphonuclear neutrophils in periodontitis patients: a case-control study.
Periodontitis
Cleavage of IgG1 and IgG3 by gingipain K from Porphyromonas gingivalis may compromise host defense in progressive periodontitis.
Periodontitis
Draft genome sequence of Fusobacterium nucleatum ChDC F128, isolated from a periodontitis lesion.
Periodontitis
EVALUATION OF BONE RESORPTIVE POTENTIAL IN THE TREATMENT OF GENERALIZED PERIODONTITIS.
Periodontitis
Gingival tissue human beta-defensin levels in relation to infection and inflammation.
Periodontitis
Identification of proteases from periodontopathogenic bacteria as activators of latent human neutrophil and fibroblast-type interstitial collagenases.
Periodontitis
Latency, thermal stability, and identification of an inhibitory compound of mirolysin, a secretory protease of the human periodontopathogen Tannerella forsythia.
Periodontitis
Metabolomics Reveals Elevated Macromolecular Degradation in Periodontal Disease.
Periodontitis
MMP-8 -799 C>T genetic polymorphism is associated with the susceptibility to chronic and aggressive periodontitis in Taiwanese.
Periodontitis
On site visual detection of Porphyromonas gingivalis related periodontitis by using a magnetic-nanobead based assay for gingipains protease biomarkers.
Periodontitis
Protease activity in gingival crevicular fluid from discrete periodontal sites in humans with periodontitis or gingivitis.
Periodontitis
Review of the association between periodontitis and chronic obstructive pulmonary disease in smokers.
Periodontitis
Role of salivary leukocyte protease inhibitor in periodontal disease progression.
Periodontitis
Sequence variations in rgpA and rgpB of Porphyromonas gingivalis in periodontitis.
Periodontitis
Serum and salivary matrix metalloproteinases, neutrophil elastase, myeloperoxidase in patients with chronic or aggressive periodontitis.
Periodontitis
Tobacco smoking and neutrophil activity in patients with periodontal disease.
Periodontitis
Transcriptome sequencing of gingival biopsies from chronic periodontitis patients reveals novel gene expression and splicing patterns.
Periodontitis
[Cloning and sequence analysis of a sialidase gene (siaHI) from Bacteroides forsythus ATCC 43037]
Periodontitis
[Determination of protease activity in the contents of periodontal pockets in chronic marginal periodontitis]
Periodontitis
[Protease activity and anti-protease activity in the saliva in chronic marginal periodontitis]
Periodontitis
[Protease activity of microflora in the oral cavity of patients with periodontitis]
Periodontitis
[The correlationship between the protease activity and the epithelial cells in the saliva from the patients with gingivitis or marginal periodontitis (author's transl)]
Peripheral Arterial Disease
Octahydrocyclopenta[c]pyridine and octahydrocyclopenta[c]pyran analogues as a protease activated receptor 1 (PAR1) antagonist.
Peripheral Arterial Disease
Of Mice and Men: Neuropeptide Y and Its Receptors Are Associated with Atherosclerotic Lesion Burden and Vulnerability.
Peripheral Arterial Disease
Protein Z-dependent protease inhibitor and protein Z in peripheral arterial disease patients.
Peripheral Arterial Disease
Trans-fused 5-[(tert-Butoxtycarbonyl)amino]octahydroindenes as a protease activated receptor-1 (PAR1) antagonist.
Peripheral Nerve Injuries
A derivative of the plasma protease inhibitor alpha(2)-macroglobulin regulates the response to peripheral nerve injury.
Peripheral Nerve Injuries
Cytokine regulation of MMP-9 in peripheral glia: implications for pathological processes and pain in injured nerve.
Peripheral Nerve Injuries
Neural thrombin and protease nexin I kinetics after murine peripheral nerve injury.
Peripheral Nerve Injuries
Peripheral nerve injury induced expression of mRNA for serine protease inhibitor 3 in the rat facial and hypoglossal nuclei but not in the spinal cord.
Peripheral Vascular Diseases
Beneficial effects of a serine protease inhibitor in peripheral vascular disease.
Peritoneal Neoplasms
Improved detection of ovarian cancer metastases by intraoperative quantitative fluorescence protease imaging in a pre-clinical model.
Peritonitis
Characterization of amino acid substitutions in feline coronavirus 3C-like protease from a cat with feline infectious peritonitis treated with a protease inhibitor.
Peritonitis
Collagenase and elastase released during peritonitis are complexed by plasma protease inhibitors.
Peritonitis
Demonstration and semiquantitative determination of complexes between various proteases and human alpha2-macroglobulin.
Peritonitis
Feline coronavirus drug inhibits the main protease of SARS-CoV-2 and blocks virus replication.
Peritonitis
Neutrophil and macrophage cell surface CSF-1 shed by ADAM17 drives mouse macrophage proliferation in acute and chronic inflammation.
Peritonitis
Pancreatic injuries in rats with fecal peritonitis: protective effect of a new synthetic protease inhibitor, sepinostat mesilate (FUT-187).
Peritonitis
Protease inhibitor GC376 for COVID-19: Lessons learned from feline infectious peritonitis.
Peritonitis
Protease inhibitor reduces loss of tensile strength in rat anastomosis with peritonitis.
Peritonitis
Protease-antiprotease levels and whole-blood chemiluminescence in acute peritonitis.
Peritonitis
[Parenteral use of an immobilized microbial protease in the combined treatment of experimental peritonitis]
Peritonitis
[Studies on fibrinolysis and ascites accumulation associated with peritonitis carcinomatosa--effects of protease inhibitors (PI) on MM2 ascites tumor growth, ascites accumulation and fibrinolysis]
Persistent Infection
Activated ClpP kills persisters and eradicates a chronic biofilm infection.
Persistent Infection
Boceprevir: a recently approved protease inhibitor for hepatitis C virus infection.
Persistent Infection
Cysteine protease isoforms from Trypanosoma cruzi, cruzipain 2 and cruzain, present different substrate preference and susceptibility to inhibitors.
Persistent Infection
Development of a high-throughput pyrosequencing assay for monitoring temporal evolution and resistance associated variant emergence in the Hepatitis C virus protease coding-region.
Persistent Infection
Development of an intergenotypic hepatitis C virus (HCV) cell culture method to assess antiviral susceptibilities and resistance development of HCV NS3 protease genes from HCV genotypes 1 to 6.
Persistent Infection
Direct acting antivirals for the treatment of chronic hepatitis C: one pill a day for tomorrow.
Persistent Infection
Efficacy of constant infusion of A-77003, an inhibitor of the human immunodeficiency virus type 1 (HIV-1) protease, in limiting acute HIV-1 infection in vitro.
Persistent Infection
European recommendations for the clinical use of HIV drug resistance testing: 2011 update.
Persistent Infection
Expression and translocation of chlamydial protease during acute and persistent infection of the epithelial HEp-2 cells with Chlamydophila (Chlamydia) pneumoniae.
Persistent Infection
Genotypic resistance in plasma and peripheral blood lymphocytes in a group of naive HIV-1 patients.
Persistent Infection
Hepatitis C virus protease NS3/4A cleaves mitochondrial antiviral signaling protein off the mitochondria to evade innate immunity.
Persistent Infection
Mutations in reovirus outer-capsid protein sigma3 selected during persistent infections of L cells confer resistance to protease inhibitor E64.
Persistent Infection
Mycobacterium tuberculosis MycP1 protease plays a dual role in regulation of ESX-1 secretion and virulence.
Persistent Infection
Phenotypic characterization of clonal and nonclonal Pseudomonas aeruginosa strains isolated from lungs of adults with cystic fibrosis.
Persistent Infection
Repurposing Saquinavir for Host-Directed Therapy to Control Mycobacterium Tuberculosis Infection.
Persistent Infection
Role of protease in mouse hepatitis virus-induced cell fusion. Studies with a cold-sensitive mutant isolated from a persistent infection.
Persistent Infection
Serine protease(s) secreted by the nematode Trichuris muris degrade the mucus barrier.
Persistent Infection
Structural and Antiviral Studies of the Human Norovirus GII.4 Protease.
Persistent Infection
The Brucella abortus Lon functions as a generalized stress response protease and is required for wild-type virulence in BALB/c mice.
Persistent Infection
The cytokine balance in the maintenance of a persistent infection with Salmonella enterica serovar Typhimurium in mice.
Persistent Infection
The first wave: HCV NS3 protease inhibitors telaprevir and boceprevir.
Persistent Infection
The Pseudomonas aeruginosa periplasmic protease CtpA can affect systems that impact its ability to mount both acute and chronic infections.
Persistent Infection
Toxoplasma Cathepsin Protease B and Aspartyl Protease 1 Are Dispensable for Endolysosomal Protein Digestion.
Persistent Infection
Triple therapy with boceprevir or telaprevir for prior HCV non-responders.
Persistent Infection
[HIV reproduction inhibition by amino acid and dipeptide derivatives of fullerene C60]
Persistent Infection
[Management of side effects induced by antiviral therapy for chronic hepatitis infection].
Pharyngitis
An Experimental Group A Streptococcus Vaccine That Reduces Pharyngitis and Tonsillitis in a Nonhuman Primate Model.
Pheochromocytoma
Co-expression of PC2 and proenkephalin in human tumoral adrenal medullary tissues.
Pheochromocytoma
LONP1 induction by SRT1720 attenuates mitochondrial dysfunction against high glucose induced neurotoxicity in PC12 cells.
Pheochromocytoma
Sunghyangjungisan protects PC12 cells against neurotoxicity elicited by withdrawal of trophic support via CRE activation.
phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase deficiency
Phosphatase and tensin homologue deficiency in glioblastoma confers resistance to radiation and temozolomide that is reversed by the protease inhibitor nelfinavir.
Photophobia
Genotype-Phenotype Correlations Emerging from the Identification of Missense Mutations in MBTPS2.
Phytoplasma Disease
Characterization of a protease produced by a Trichoderma harzianum isolate which controls cocoa plant witches' broom disease.
Picornaviridae Infections
Coxsackievirus B3 Responds to Polyamine Depletion via Enhancement of 2A and 3C Protease Activity.
Pituitary ACTH Hypersecretion
Biophysical and structural insight into the USP8/14-3-3 interaction.
Pituitary ACTH Hypersecretion
Clinical characteristics and surgical outcome in USP8-mutated human adrenocorticotropic hormone-secreting pituitary adenomas.
Pituitary ACTH Hypersecretion
PATHOGENESIS OF CUSHING DISEASE: AN UPDATE ON THE GENETICS OF CORTICOTROPINOMAS.
Pituitary ACTH Hypersecretion
Role of tyrosine kinase inhibitors in the treatment of pituitary tumours: from bench to bedside.
Pituitary ACTH Hypersecretion
Somatic USP8 Gene Mutations Are a Common Cause of Pediatric Cushing Disease.
Pituitary ACTH Hypersecretion
The Gene of the Ubiquitin-Specific Protease 8 Is Frequently Mutated in Adenomas Causing Cushing's Disease.
Pituitary ACTH Hypersecretion
The USP8 mutational status may predict long-term remission in patients with Cushing's disease.
Pituitary ACTH Hypersecretion
Ubiquitin-specific protease 8 inhibitor suppresses adrenocorticotropic hormone production and corticotroph tumor cell proliferation.
Pituitary Neoplasms
Bioregulatory role of the kallikrein-kinin system in the normal pituitary gland and its tumours.
Pituitary Neoplasms
Emerging Role of USP8, HMGA, and Non-Coding RNAs in Pituitary Tumorigenesis.
Pituitary Neoplasms
Immunohistochemical demonstration of alpha1-antichymotrypsin and alpha1 -antitrypsin in the normal pituitary gland and its tumors.
Pituitary Neoplasms
Lack of Ubiquitin Specific Protease 8 (USP8) Mutations in Canine Corticotroph Pituitary Adenomas.
Pituitary Neoplasms
Pttg1/securin is required for the branching morphogenesis of the mammary gland and suppresses mammary tumorigenesis.
Pituitary Neoplasms
Somatic and germline mutations in the pathogenesis of pituitary adenomas.
Pituitary Neoplasms
Type 2 iodothyronine deiodinase in rat pituitary tumor cells is inactivated in proteasomes.
Placenta Diseases
miR-34a expression, epigenetic regulation, and function in human placental diseases.
Plague
A dual role for the Plasminogen activator protease during the pre-inflammatory phase of primary pneumonic plague.
Plague
A plasminogen-activating protease specifically controls the development of primary pneumonic plague.
Plague
Deletion of Braun lipoprotein and plasminogen activating protease-encoding genes attenuates Yersinia pestis in mouse models of bubonic and pneumonic plague.
Plague
Modeling Pneumonic Plague in Human Precision-Cut Lung Slices Highlights a Role for the Plasminogen Activator Protease in Facilitating Type 3 Secretion.
Plague
Protein regions important for plasminogen activation and inactivation of alpha2-antiplasmin in the surface protease Pla of Yersinia pestis.
Plague
Relative immunogenicity and protection potential of candidate Yersinia Pestis antigens against lethal mucosal plague challenge in Balb/C mice.
Plague
Temperature-Induced Changes in the Lipopolysaccharide of Yersinia pestis Affect Plasminogen Activation by the Pla Surface Protease.
Plasmablastic Lymphoma
Survival in HIV-infected patients with lymphoma according to the choice of antiretroviral treatment: an observational multicentre study.
Plasmacytoma
Inhibition of initiation of protein synthesis in mammalian tissue culture cells by L-1-tosylamido-2-phenylethyl chloromethyl ketone.
Pleural Effusion
Marked effect of octreotide acetate in a case of pancreatic pleural effusion.
Pleural Effusion
Use of a protease inhibitor, ulinastatin, for reexpansion pulmonary edema following evacuation of bilateral pleural effusion.
Pleural Effusion
[Trypsin-induced polyseritis: action of di-iso-propyl-fluorophosphate; evolution of the proteas activity of effusion; comparison with elastase]
Pleurisy
Fibrinolytic and coagulation mechanisms in stages of inflammation: a study of BCG-induced pleural exudate in guinea pig.
Pleuropneumonia
Actinobacillus pleuropneumoniae metalloprotease: cloning and in vivo expression.
Pneumococcal Infections
NLRP3/ASC/Caspase-1 axis and serine protease activity are involved in neutrophil IL-1? processing during Streptococcus pneumoniae infection.
Pneumonia
A Proteolytic Complex Targets Multiple Cell Wall Hydrolases in Pseudomonas aeruginosa.
Pneumonia
A Unique Protease Cleavage Site Predicted in the Spike Protein of the Novel Pneumonia Coronavirus (2019-nCoV) Potentially Related to Viral Transmissibility.
Pneumonia
Alpha-1 antitrypsin reduces severity of pseudomonas pneumonia in mice and inhibits epithelial barrier disruption and pseudomonas invasion of respiratory epithelial cells.
Pneumonia
Alveolar macrophages play a key role in cockroach-induced allergic inflammation via TNF-? pathway.
Pneumonia
Analysis of proteolytic enzymes and their natural inhibitors in serum and bronchial lavage fluid in atopic bronchial asthma, chronic bronchitis and pneumonia.
Pneumonia
Analysis of type I IFN response and T cell activation in severe COVID-19/HIV-1 coinfection: A case report.
Pneumonia
Author Correction: Effects of the serine protease inhibitor rBmTI-A in an experimental mouse model of chronic allergic pulmonary inflammation.
Pneumonia
Comparison of the effects of a multi-component vaccine and a formalin-killed cell vaccine on protection against enzootic of hemorrhagic pneumonia due to Pseudomonas aeruginosa in mink.
Pneumonia
Deregulated Stat3 signaling dissociates pulmonary inflammation from emphysema in gp130 mutant mice.
Pneumonia
Differential protease, innate immunity, and NF-kappaB induction profiles during lung inflammation induced by subchronic cigarette smoke exposure in mice.
Pneumonia
Effectiveness of immunization with multicomponent vaccines in protection against hemorrhagic pneumonia due to Pseudomonas aeruginosa infection in mink.
Pneumonia
Effectiveness of immunization with single and multi-component vaccines prepared from a common antigen (OEP), protease and elastase toxoids of Pseudomonas aeruginosa on protection against hemorrhagic pneumonia in mink due to P. aeruginosa.
Pneumonia
Effects of an isogenic Zn-metalloprotease-deficient mutant of Legionella pneumophila in a guinea-pig pneumonia model.
Pneumonia
Effects of the common protective antigen (OEP) and toxoids of protease and elastase from Pseudomonas aeruginosa on protection against hemorrhagic pneumonia in mink.
Pneumonia
Effects of the serine protease inhibitor rBmTI-A in an experimental mouse model of chronic allergic pulmonary inflammation.
Pneumonia
Examination of Haemophilus pleuropneumoniae for immunoglobulin A protease activity.
Pneumonia
Immunocytochemical demonstration of the association between Legionella pneumophila, its tissue-destructive protease, and pulmonary lesions in experimental legionnaires' disease.
Pneumonia
Importance of serratia protease in the pathogenesis of experimental Serratia marcescens pneumonia.
Pneumonia
In vitro activity of human immunodeficiency virus protease inhibitors against Pneumocystis carinii.
Pneumonia
Inhibition of NF-kappaB activation and augmentation of IkappaBbeta by secretory leukocyte protease inhibitor during lung inflammation.
Pneumonia
Inhibition of Pseudomonas aeruginosa secreted virulence factors reduces lung inflammation in CF mice.
Pneumonia
Inhibitory effect of a protease inhibitor, leupeptin, on the development of influenza pneumonia, mediated by concomitant bacteria.
Pneumonia
Integrated innate mechanisms involved in airway allergic inflammation to the serine protease subtilisin.
Pneumonia
Interactions between bacteria and influenza A virus in the development of influenza pneumonia.
Pneumonia
Lineage-specific regulation of inducible and constitutive mast cells in allergic airway inflammation.
Pneumonia
Mast cells contribute to bleomycin-induced lung inflammation and injury in mice through a chymase/mast cell protease 4-dependent mechanism.
Pneumonia
Microbial diversity in bioaerosol samples causing ODTS compared to reference bioaerosol samples as measured using Illumina sequencing and MALDI-TOF.
Pneumonia
Mycoplasma hyopneumoniae type I signal peptidase: Expression and evaluation of its diagnostic potential.
Pneumonia
Neutrophil-targeted, protease-activated pulmonary drug delivery blocks airway and systemic inflammation.
Pneumonia
Out-Smarting the Host: Bacteria Maneuvering the Immune Response to Favor Their Survival.
Pneumonia
p-Coumaric Acid, a Major Active Compound of Bambusae Caulis in Taeniam, Suppresses Cigarette Smoke-Induced Pulmonary Inflammation.
Pneumonia
Plasma concentrations of secretory leukocyte protease inhibitor (SLPI) differ depending on etiology and severity in community-onset bloodstream infection.
Pneumonia
Pretreatment of a matrix metalloproteases inhibitor and aprotinin attenuated the development of acute pancreatitis-induced lung injury in rat model.
Pneumonia
Protease activated receptor 4 limits bacterial growth and lung pathology during late stage Streptococcus pneumoniae induced pneumonia in mice.
Pneumonia
Protease inhibitors in bronchoalveolar lavage fluid from neonates with special reference to secretory leukocyte protease inhibitor.
Pneumonia
Protection against hemorrhagic pneumonia of mink by Pseudomonas aeruginosa multicomponent vaccine.
Pneumonia
Protection of mice by a protease inhibitor, aprotinin, against lethal Sendai virus pneumonia.
Pneumonia
Respiratory syncytial virus infections enhance cigarette smoke induced COPD in mice.
Pneumonia
Retinoic-Acid-Receptor-Related Orphan Nuclear Receptor Alpha Is Required for Natural Helper Cell Development and Allergic Inflammation.
Pneumonia
Safety of protease inhibitors and Arbidol for SARS-CoV-2 pneumonia in Zhejiang Province, China.
Pneumonia
SCH79797 improves outcomes in experimental bacterial pneumonia by boosting neutrophil killing and direct antibiotic activity.
Pneumonia
Secretory leukocyte protease inhibitor and lung inflammation in developing bronchopulmonary dysplasia.
Pneumonia
Specification of type 2 innate lymphocytes by the transcriptional determinant Gfi1.
Pneumonia
Streptococcus pneumoniae serine protease HtrA, but not SFP or PrtA, is a major virulence factor in pneumonia.
Pneumonia
Synergistic role of staphylococcal proteases in the induction of influenza virus pathogenicity.
Pneumonia
The endoplasmic reticulum remains functionally connected by vesicular transport after its fragmentation in cells expressing Z-?1-antitrypsin.
Pneumonia
The probiotic strain Escherichia coli Nissle 1917 prevents papain-induced respiratory barrier injury and severe allergic inflammation in mice.
Pneumonia
THE SERUM FERMENTS AND ANTIFERMENT DURING PNEUMONIA : STUDIES ON FERMENT ACTION. XXIV.
Pneumonia
The TLR4-PAR1 Axis Regulates Bone Marrow Mesenchymal Stromal Cell Survival and Therapeutic Capacity in Experimental Bacterial Pneumonia.
Pneumonia
Thrombin-induced CCAAT/enhancer-binding protein ? activation and IL-8/CXCL8 expression via MEKK1, ERK, and p90 ribosomal S6 kinase 1 in lung epithelial cells.
Pneumonia
Thrombin-induced IL-8/CXCL8 release is mediated by CK2, MSK1, and NF-?B pathways in human lung epithelial cells.
Pneumonia
Ubiquitin-Specific Protease 14 (USP14) Aggravates Inflammatory Response and Apoptosis of Lung Epithelial Cells in Pneumonia by Modulating Poly (ADP-Ribose) Polymerase-1 (PARP-1).
Pneumonia
Vaccine-Induced Immunogenicity and Protection Against Pneumocystis Pneumonia in a Nonhuman Primate Model of HIV and Pneumocystis Coinfection.
Pneumonia
[Metabolic function characteristics and respiratory pathology of premature infants]
Pneumonia
[Validation of the use of protease inhibitors in severe forms of pneumonia in young infants]
Pneumonia, Bacterial
A computational drug repurposing approach in identifying the cephalosporin antibiotic and anti-hepatitis C drug derivatives for COVID-19 treatment.
Pneumonia, Bacterial
Effect of antiretroviral therapy on the incidence of bacterial pneumonia in patients with advanced HIV infection.
Pneumonia, Bacterial
Incidence and risk factors of bacterial pneumonia requiring hospitalization in HIV-infected patients started on a protease inhibitor-containing regimen.
Pneumonia, Bacterial
Reappraisal of the aetiology and prognostic factors of severe acute respiratory failure in HIV patients.
Pneumonia, Bacterial
[Proteolytic activities in bronchoalveolar lavage fluid in pneumonia and chronic bronchitis]
Pneumonia, Pneumococcal
Protease and antiprotease responses in lung and peripheral blood in experimental canine pneumococcal pneumonia.
Pneumonia, Pneumococcal
Subcellular localization and further characterization of a new elastase inhibitor from pneumococci.
Pneumonia, Pneumocystis
In vitro activity of human immunodeficiency virus protease inhibitors against Pneumocystis carinii.
Pneumothorax
[Alternation of protease inhibitors and hemostasis system in treatment of spontaneous pneumothorax]
Poliomyelitis
Activator of plasminogen and protease from various cell cultures and present in poliomyelitis vaccine.
Poliomyelitis
beta-Galactosidase containing a human immunodeficiency virus protease cleavage site is cleaved and inactivated by human immunodeficiency virus protease.
Polyarteritis Nodosa
Detection of autoantibodies against myeloid lysosomal enzymes: a useful adjunct to classification of patients with biopsy-proven necrotizing arteritis.
Polycystic Ovary Syndrome
Comparison of body mass index and metabolic parameters with serum vaspin levels in women with polycystic ovary syndrome.
Polycystic Ovary Syndrome
Delayed healing and induction of secretory leukocyte protease inhibitor in polycystic ovary syndrome rat skin wounds.
Polycystic Ovary Syndrome
Serum visceral adipose tissue-derived serine protease inhibitor concentrations in human obesity and polycystic ovary syndrome.
Polycystic Ovary Syndrome
Vaspin regulates the osteogenic differentiation of MC3T3-E1 through the PI3K-Akt/miR-34c loop.
Polymyalgia Rheumatica
Association of osteoarthritis with homozygosity for a 5.8 kb Taq I fragment of the alpha 1-antichymotrypsin gene.
Polyneuropathies
Activities of some antioxidative and hexose monophosphate shunt enzymes of skeletal muscle in neuromuscular diseases.
Polyneuropathies
Clinical and laboratory signs of mitochondrial dysfunction secondary to nucleoside analogue antiretroviral therapy are reversible.
Polyneuropathies
Diagnosis of silent myocardial ischemia during the staging of HIV-associated lymphoma with FDG PET/CT.
Polyneuropathies
DJ-1 degrades transthyretin and an inactive form of DJ-1 is secreted in familial amyloidotic polyneuropathy.
Polyneuropathies
Human immunodeficiency virus protease inhibitors and risk for peripheral neuropathy.
Polyneuropathies
Sensory neuropathy and metabolic risk factors in human immune deficiency virus infected South Africans receiving protease inhibitors.
Polyneuropathies
Studies of protease and protease inhibitors in familial amyloidotic polyneuropathy.
Porcine Reproductive and Respiratory Syndrome
Identification of a single nucleotide promoter polymorphism regulating the transcription of ubiquitin specific protease 18 gene related to the resistance to porcine reproductive and respiratory syndrome virus infection.
Porcine Reproductive and Respiratory Syndrome
Identification of nonessential regions of the nsp2 replicase protein of porcine reproductive and respiratory syndrome virus strain VR-2332 for replication in cell culture.
Porcine Reproductive and Respiratory Syndrome
Identification of two antiviral inhibitors targeting 3C-like serine/3C-like protease of porcine reproductive and respiratory syndrome virus and porcine epidemic diarrhea virus.
Porcine Reproductive and Respiratory Syndrome
Insights into the Porcine Reproductive and Respiratory Syndrome Virus Viral Ovarian Tumor Domain Protease Specificity for Ubiquitin and Interferon Stimulated Gene Product 15.
Porcine Reproductive and Respiratory Syndrome
Monitoring activation of the antiviral pattern recognition receptors RIG-I and PKR by limited protease digestion and native PAGE.
Porcine Reproductive and Respiratory Syndrome
Proteolytic products of the porcine reproductive and respiratory syndrome virus nsp2 replicase protein.
Porcine Reproductive and Respiratory Syndrome
Signaling in innate immunity and inflammation.
Porcine Reproductive and Respiratory Syndrome
Structure and cleavage specificity of the chymotrypsin-like serine protease (3CLSP/nsp4) of Porcine Reproductive and Respiratory Syndrome Virus (PRRSV).
Porcine Reproductive and Respiratory Syndrome
The cysteine protease domain of porcine reproductive and respiratory syndrome virus nonstructural protein 2 possesses deubiquitinating and interferon antagonism functions.
Porcine Reproductive and Respiratory Syndrome
The effects of the context-dependent codon usage bias on the structure of the nsp1? of porcine reproductive and respiratory syndrome virus.
Porcine Reproductive and Respiratory Syndrome
[Expression and purification of porcine reproductive and respiratory syndrome virus Nsp2 protein and analysis of cleavage activity]
Porphyrias
[The HLA and protease inhibitor (Pi) system in erythropoietic (hepatic) protoporphyria. Family studies]
Pouchitis
Fecal Proteases from Pouchitis Patients Activate Protease Activating Receptor-2 to Disrupt the Epithelial Barrier.
Pre-Eclampsia
8C.02: THE SERINE PROTEASE PROSTASIN IS ABERRANTLY FILTRATED IN URINE IN PREECLAMPSIA WITH SIMILAR LEVELS IN PLASMA AND PLACENTA TISSUE COMPARED TO NORMAL PREGNANCY.
Pre-Eclampsia
Altered protease expression by periarterial trophoblast cells in severe early-onset preeclampsia with IUGR.
Pre-Eclampsia
Alternative forms of a novel aspartyl protease gene are differentially expressed in human gestational tissues.
Pre-Eclampsia
Antithrombin III prevents blood pressure elevation and proteinuria induced by high salt intake in pregnant stroke-prone spontaneously hypertensive rats.
Pre-Eclampsia
Changes of plasma protease inhibitors in late pregnancy, during delivery and puerperium in normal women and in preeclampsia.
Pre-Eclampsia
Chymotrypsin Enhances Soluble Fms-Like Tyrosine Kinase 1 Production Through Protease-Activated Receptor 2 in Placenta-Derived Immortalized Human Trophoblast Cells.
Pre-Eclampsia
Complement activation, circulating protease inhibitors and pregnancy-associated proteins in severe pre-eclampsia.
Pre-Eclampsia
Correlation of Plasma Neutrophil Elastase Activity and Endogenous Protease Inhibitor Levels with the Severity of Pre-eclampsia.
Pre-Eclampsia
Differential expression of human placental PAPP-A2 over gestation and in preeclampsia.
Pre-Eclampsia
Discerning the mechanism of action of HtrA4: a serine protease implicated in the cell death pathway.
Pre-Eclampsia
Elevated protease HtrA4 in the maternal circulation of preeclampsia may contribute to endothelial barrier disruption by cleaving key junctional protein VE-cadherin.
Pre-Eclampsia
Expressional and epigenetic alterations of placental serine protease inhibitors: SERPINA3 is a potential marker of preeclampsia.
Pre-Eclampsia
Heparin cofactor activity and antithrombin III antigen levels in preeclampsia.
Pre-Eclampsia
Highly significant association between two common single nucleotide polymorphisms in CORIN gene and preeclampsia in Caucasian women.
Pre-Eclampsia
HtrA4 is up-regulated during trophoblast syncytialization and BeWo cells fail to syncytialize without HtrA4.
Pre-Eclampsia
Increased levels of pregnancy-associated plasma protein-A2 in the serum of pre-eclamptic patients.
Pre-Eclampsia
Interaction between pregnancy-induced bioactive peptides and the placental proteases.
Pre-Eclampsia
MMP-14 Is Expressed in Preeclamptic Placentas and Mediates Release of Soluble Endoglin.
Pre-Eclampsia
Placenta-derived chymotrypsin-like protease (CLP) disturbs endothelial junctional structure in preeclampsia.
Pre-Eclampsia
Plasma concentration of protein Z-dependent protease inhibitor and ZPI exon 3 mutations in preeclampsia.
Pre-Eclampsia
Pregnancy-Associated Cardiac Hypertrophy in Corin-Deficient Mice: Observations in a Transgenic Model of Preeclampsia.
Pre-Eclampsia
Processing of procorticotropin-releasing hormone (pro-CRH): molecular forms of CRH in normal and preeclamptic pregnancy.
Pre-Eclampsia
Regulation of pregnancy-associated plasma protein A2 (PAPPA2) in a human placental trophoblast cell line (BeWo).
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Evaluation of Apaf-1 and procaspases-2, -3, -7, -8, and -9 as potential prognostic markers in acute leukemia.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Prognostic value of protease activated receptor-1 in children with acute lymphoblastic leukemia.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Suppressive activity of protease inhibitors from buckwheat seeds against human T-acute lymphoblastic leukemia cell lines.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
[Preparation of novel specific aminopeptidase inhibitors with a cyclic imide skeleton]
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
A leukemia-enriched cDNA microarray platform identifies new transcripts with relevance to the biology of pediatric acute lymphoblastic leukemia.
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
ALKBH5-mediated m6A-demethylation of USP1 regulated T-cell acute lymphoblastic leukemia cell glucocorticoid resistance by Aurora B.
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
Redundancy and specificity of the metalloprotease system mediating oncogenic NOTCH1 activation in T-ALL.
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
Selective killing of human T-ALL cells: an integrated approach targeting redox homeostasis and the OMA1/OPA1 axis.
Pregnancy Complications
Elevated Levels of Estradiol in Human Immunodeficiency Virus-Infected Pregnant Women on Protease Inhibitor-Based Regimens.
Pregnancy Complications
Low Prolactin and High 20-?-Hydroxysteroid Dehydrogenase Levels Contribute to Lower Progesterone Levels in HIV-Infected Pregnant Women Exposed to Protease Inhibitor-Based Combination Antiretroviral Therapy.
Pregnancy Complications
Protease Inhibitors and Adverse Birth Outcomes: Is Progesterone the Missing Piece to the Puzzle?
Pregnancy, Ectopic
Expression of Protease HtrA1 Is Increased at the Site of Ectopic Pregnancy.
Pregnancy, Tubal
Altered secretory leukocyte protease inhibitor expression in the uterine decidua of tubal compared with intrauterine pregnancy.
Premature Birth
Association between maternal human immunodeficiency virus infection and preterm birth: A matched case-control study from a pregnancy outcome registry.
Premature Birth
Combination antiretroviral therapy with protease inhibitors in HIV-infected pregnancy.
Premature Birth
Declines in low birth weight and preterm birth among infants who were born to HIV-infected women during an era of increased use of maternal antiretroviral drugs: Pediatric Spectrum of HIV Disease, 1989-2004.
Premature Birth
Elevated protease activities in human amnion and chorion correlate with preterm premature rupture of membranes.
Premature Birth
Is protease inhibitors based antiretroviral therapy during pregnancy associated with an increased risk of preterm birth? Systematic review and a meta-analysis.
Premature Birth
Maternal antiretroviral drugs during pregnancy and infant low birth weight and preterm birth.
Premature Birth
Predictive biomarkers of preterm delivery in women with ongoing IVF pregnancies.
Premature Birth
Prenatal protease inhibitor use and risk of preterm birth among HIV-infected women initiating antiretroviral drugs during pregnancy.
Premature Birth
Protease Amplification of the Inflammatory Response Induced by Commensal Bacteria: Implications for Racial Disparity in Term and Preterm Birth.
Premature Birth
Repeat Pregnancies Among US Women Living with HIV in the SMARTT Study: Temporal Changes in HIV Disease Status and Predictors of Preterm Birth.
Premature Birth
Risk factors for preterm birth among HIV-infected pregnant Ugandan women randomized to lopinavir/ritonavir- or efavirenz-based antiretroviral therapy.
Premature Birth
The PHACS SMARTT Study: Assessment of the Safety of In Utero Exposure to Antiretroviral Drugs.
Premature Birth
The Use of Protease Inhibitors in Pregnancy: Maternal and Fetal Considerations.
Priapism
Antipsychotic-induced priapism in an HIV patient: a cytochrome P450-mediated drug interaction.
Prion Diseases
Adult human microglia secrete cytokines when exposed to neurotoxic prion protein peptide: no intermediary role for prostaglandin E2.
Prion Diseases
Cellular prion protein: A co-receptor mediating neuronal cofilin-actin rod formation induced by ?-amyloid and proinflammatory cytokines.
Prion Diseases
Characterisation of new monoclonal antibodies reacting with prions from both human and animal brain tissues.
Prion Diseases
Characterization of the F198S prion protein mutation: enhanced glycosylation and defective refolding.
Prion Diseases
CJD PrPsc removal by nanofiltration process: application to a therapeutic immunoglobulin solution (Lymphoglobuline).
Prion Diseases
Contribution of a metal-peroxide adduct to neurodegeneration is due to its oxidative protease activity.
Prion Diseases
Correction: PrPST, a Soluble, Protease Resistant and Truncated PrP Form Features in the Pathogenesis of a Genetic Prion Disease.
Prion Diseases
Creutzfeldt-Jakob disease, prion protein gene codon 129VV, and a novel PrPSc type in a young British woman.
Prion Diseases
Delivery of Therapeutic siRNA to the CNS Using Cationic and Anionic Liposomes.
Prion Diseases
Detection and characterization of proteinase K-sensitive disease-related prion protein with thermolysin.
Prion Diseases
Distinct glycoform ratios of protease resistant prion protein associated with PRNP point mutations.
Prion Diseases
Four types of scrapie in goats differentiated from each other and bovine spongiform encephalopathy by biochemical methods.
Prion Diseases
Glycosaminoglycan sulphation affects the seeded misfolding of a mutant prion protein.
Prion Diseases
Limited amplification of chronic wasting disease prions in the peripheral tissues of intracerebrally inoculated cattle.
Prion Diseases
Mapping of possible prion protein self-interaction domains using peptide arrays.
Prion Diseases
Metabotropic glutamate receptor/phospholipase C pathway: a vulnerable target to Creutzfeldt-Jakob disease in the cerebral cortex.
Prion Diseases
Monitoring immune cells trafficking fluorescent prion rods hours after intraperitoneal infection.
Prion Diseases
Prion subcellular fractionation reveals infectivity spectrum, with a high titre-low PrPres level disparity.
Prion Diseases
Prion urine comprises a glycosaminoglycan-light chain IgG complex that can be stained by Congo red.
Prion Diseases
Processing of high-titer prions for mass spectrometry inactivates prion infectivity.
Prion Diseases
Protease-resistant prion protein in brain and lymphoid organs of sheep within a naturally scrapie-infected flock.
Prion Diseases
Protease-resistant SOD1 aggregates in amyotrophic lateral sclerosis demonstrated by paraffin-embedded tissue (PET) blot.
Prion Diseases
PrP(ST), a soluble, protease resistant and truncated PrP form features in the pathogenesis of a genetic prion disease.
Prion Diseases
Rapid formation of amyloid from alpha-monomeric recombinant human PrP in vitro.
Prion Diseases
Screening a library of potential prion therapeutics against cellular prion proteins and insights into their mode of biological activities by surface plasmon resonance.
Prion Diseases
Selection of ovine PrP high-producer subclones from a transfected epithelial cell line.
Prion Diseases
Sequential appearance and accumulation of pathognomonic markers in the central nervous system of hamsters orally infected with scrapie.
Prion Diseases
Sites of prion protein accumulation in scrapie-infected mouse spleen revealed by immuno-electron microscopy.
Prion Diseases
Small ruminant nor98 prions share biochemical features with human gerstmann-sträussler-scheinker disease and variably protease-sensitive prionopathy.
Prion Diseases
Synthesis and SAR study of acridine, 2-methylquinoline and 2-phenylquinazoline analogues as anti-prion agents.
Prion Diseases
Tetracycline and its analogues as inhibitors of amyloid fibrils: searching for a geometrical pharmacophore by theoretical investigation of their conformational behavior in aqueous solution.
Prion Diseases
The architecture of prions: how understanding would provide new therapeutic insights.
Prion Diseases
The compound (3-{5-[(2,5-dimethoxyphenyl)amino]-1,3,4-thiadiazolidin-2-yl}-5,8-methoxy-2H-chromen-2-one) inhibits the prion protein conversion from PrP
Prion Diseases
The prion protein protease sensitivity, stability and seeding activity in variably protease sensitive prionopathy brain tissue suggests molecular overlaps with sporadic Creutzfeldt-Jakob disease.
Prion Diseases
Transgenic Overexpression of the Disordered Prion Protein N1 Fragment in Mice Does Not Protect Against Neurodegenerative Diseases Due to Impaired ER Translocation.
Prion Diseases
Trehalose impairs aggregation of PrPSc molecules and protects prion-infected cells against oxidative damage.
Prion Diseases
Two-dimensional mapping of three phenotype-associated isoforms of the prion protein in sporadic Creutzfeldt-Jakob disease.
Prion Diseases
[A process of programmed cell death as a mechanisms of neuronal death in prion diseases]
Progeria
Genomic Instability and DNA Damage Responses in Progeria Arising from Defective Maturation of Prelamin A.
Progeria
Nuclear envelope alterations generate an aging-like epigenetic pattern in mice deficient in Zmpste24 metalloprotease.
Progeria
Reduction of unscheduled DNA synthesis and plasminogen activator activity in Hutchinson-Gilford fibroblasts during passaging in vitro: partial correction by interferon-beta.
Progeria
RNAi of FACE1 protease results in growth inhibition of human cells expressing lamin A: implications for Hutchinson-Gilford progeria syndrome.
Prostatic Diseases
The role of molecular forms of prostate-specific antigen (PSA or hK3) and of human glandular kallikrein 2 (hK2) in the diagnosis and monitoring of prostate cancer and in extra-prostatic disease.
Prostatic Hyperplasia
Plasminogen activator activities in short-term tissue cultures of benign prostatic hyperplasia and prostatic carcinoma.
Prostatic Hyperplasia
Progression of prostate cancer: diagnostic and prognostic utility of prostate-specific antigen, alpha2-macroglobulin, and their complexes.
Prostatic Hyperplasia
Protein C inhibitor (plasminogen activator inhibitor-3) expression in the CWR22 prostate cancer xenograft.
Prostatic Hyperplasia
Serum total and free prostate-specific antigen for breast cancer diagnosis in women.
Prostatic Hyperplasia
The TMPRSS2 gene encoding transmembrane serine protease is overexpressed in a majority of prostate cancer patients: detection of mutated TMPRSS2 form in a case of aggressive disease.
Prostatic Intraepithelial Neoplasia
Prostate-specific antigen, a serine protease, facilitates human prostate cancer cell invasion.
Prostatic Neoplasms
A claudin 3 and claudin 4-targeted Clostridium perfringens protoxin is selectively cytotoxic to PSA-producing prostate cancer cells.
Prostatic Neoplasms
A new method to assay protease based on amyloid misfolding: application to prostate cancer diagnosis using a panel of proteases biomarkers.
Prostatic Neoplasms
A Novel High Content Imaging-Based Screen Identifies the Anti-Helminthic Niclosamide as an Inhibitor of Lysosome Anterograde Trafficking and Prostate Cancer Cell Invasion.
Prostatic Neoplasms
A novel transcript from the KLKP1 gene is androgen regulated, down-regulated during prostate cancer progression and encodes the first non-serine protease identified from the human kallikrein gene locus.
Prostatic Neoplasms
A phase I trial of DNA vaccination with a plasmid expressing prostate-specific antigen in patients with hormone-refractory prostate cancer.
Prostatic Neoplasms
A Phase II, Multicenter, Single-Arm Study of Mipsagargin (G-202) as a Second-Line Therapy Following Sorafenib for Adult Patients with Progressive Advanced Hepatocellular Carcinoma.
Prostatic Neoplasms
A prostate-specific antigen activated N-(2-hydroxypropyl) methacrylamide copolymer prodrug as dual-targeted therapy for prostate cancer.
Prostatic Neoplasms
A recombinant vaccinia virus expressing human prostate-specific antigen (PSA): safety and immunogenicity in a non-human primate.
Prostatic Neoplasms
A Single Glycan at the 99-Loop of Human Kallikrein-related Peptidase 2 Regulates Activation and Enzymatic Activity.
Prostatic Neoplasms
Aberrant expression of the maspin gene associated with epigenetic modification in melanoma cells.
Prostatic Neoplasms
Activatable Zymography Probes Enable In Situ Localization of Protease Dysregulation in Cancer.
Prostatic Neoplasms
Adeno-associated virus 2-mediated intratumoral prostate cancer gene therapy: long-term maspin expression efficiently suppresses tumor growth.
Prostatic Neoplasms
An allosteric anti-hepsin antibody derived from a constrained phage display library.
Prostatic Neoplasms
Androgen-Induced TMPRSS2 Activates Matriptase and Promotes Extracellular Matrix Degradation, Prostate Cancer Cell Invasion, Tumor Growth, and Metastasis.
Prostatic Neoplasms
Anti-cancer activity of the novel 2-hydroxydiarylamide derivatives IMD-0354 and KRT1853 through suppression of cancer cell invasion, proliferation, and survival mediated by TMPRSS4.
Prostatic Neoplasms
APAF-1-ALT, a novel alternative splicing form of APAF-1, potentially causes impeded ability of undergoing DNA damage-induced apoptosis in the LNCaP human prostate cancer cell line.
Prostatic Neoplasms
Application of in-gel protease assay in a biological sample: characterization and identification of urokinase-type plasminogen activator (uPA) in secreted proteins from a prostate cancer cell line PC-3.
Prostatic Neoplasms
Association of prostate-specific antigen promoter genotype with clinical and histopathologic features of prostate cancer.
Prostatic Neoplasms
Autocrine regulation of prostate-specific antigen gene expression in a human prostatic cancer (LNCaP) subline.
Prostatic Neoplasms
Biomarkers in prostate cancer diagnosis and prognosis: beyond prostate-specific antigen.
Prostatic Neoplasms
Blood-based and urinary prostate cancer biomarkers: a review and comparison of novel biomarkers for detection and treatment decisions.
Prostatic Neoplasms
Calpain activation through galectin-3 inhibition sensitizes prostate cancer cells to cisplatin treatment.
Prostatic Neoplasms
Camalexin-induced apoptosis in prostate cancer cells involves alterations of expression and activity of lysosomal protease cathepsin d.
Prostatic Neoplasms
Caspase protease manipulation: a novel approach to apoptotic induction in prostate cancer.
Prostatic Neoplasms
Catalytic cleavage of the androgen-regulated TMPRSS2 protease results in its secretion by prostate and prostate cancer epithelia.
Prostatic Neoplasms
Cell-type-specific repression of the maspin gene is disrupted frequently by demethylation at the promoter region in gastric intestinal metaplasia and cancer cells.
Prostatic Neoplasms
Chickpea (Cicer arietinum) and other plant-derived protease inhibitor concentrates inhibit breast and prostate cancer cell proliferation in vitro.
Prostatic Neoplasms
Classification of prostate cancer using a protease activity nanosensor library.
Prostatic Neoplasms
Cleavage of beta-catenin by calpain in prostate and mammary tumor cells.
Prostatic Neoplasms
Clonal evaluation of early onset prostate cancer by expression profiling of ERG, SPINK1, ETV1, and ETV4 on whole-mount radical prostatectomy tissue.
Prostatic Neoplasms
Compartmentalized expression of kallikrein 4 (KLK4/hK4) isoforms in prostate cancer: nuclear, cytoplasmic and secreted forms.
Prostatic Neoplasms
Conformational and biochemical analysis of the cyclic peptides which modulate serine protease activity.
Prostatic Neoplasms
Crystal structure of the inhibitor-free form of the serine protease kallikrein-4.
Prostatic Neoplasms
Curcumin-targeting Pericellular Serine Protease Matriptase Role in Suppression of Prostate Cancer Cell Invasion, Tumor Growth and Metastasis.
Prostatic Neoplasms
Decreased expression of serine protease inhibitor family G1 (SERPING1) in prostate cancer can help distinguish high-risk prostate cancer and predicts malignant progression.
Prostatic Neoplasms
Design of drug-like hepsin inhibitors against prostate cancer and kidney stones.
Prostatic Neoplasms
Design of new and sensitive fluorogenic substrates for human kallikrein hK3 (prostate-specific antigen) derived from semenogelin sequences.
Prostatic Neoplasms
Detection of TMPRSS2-ETS fusions by a multiprobe fluorescence in situ hybridization assay for the early diagnosis of prostate cancer: a pilot study.
Prostatic Neoplasms
Deubiquitinating enzyme USP33 restrains docetaxel-induced apoptosis via stabilising the phosphatase DUSP1 in prostate cancer.
Prostatic Neoplasms
Does PSA play a role as a promoting agent during the initiation and/or progression of prostate cancer?
Prostatic Neoplasms
Down-regulation of prostasin serine protease: a potential invasion suppressor in prostate cancer.
Prostatic Neoplasms
Effect of Silibinin on Maspin and ER? Gene Expression in MCF-7 Human Breast Cancer Cell Line.
Prostatic Neoplasms
Ellagic Acid inhibits migration and invasion by prostate cancer cell lines.
Prostatic Neoplasms
Enhanced prostate cancer targeting by modified protease sensitive photosensitizer prodrugs.
Prostatic Neoplasms
ERG immunohistochemistry and clinicopathologic characteristics in Korean prostate adenocarcinoma patients.
Prostatic Neoplasms
Evaluation of an automated chemiluminescent immunoassay for complexed PSA on the Bayer ACS:180 system.
Prostatic Neoplasms
Evidence that the prostate-specific antigen (PSA)/Zn2+ axis may play a role in human prostate cancer cell invasion.
Prostatic Neoplasms
Excess hepsin proteolytic activity limits oncogenic signaling and induces ER stress and autophagy in prostate cancer cells.
Prostatic Neoplasms
Expression and regulation of tumor suppressor gene maspin in human bladder cancer.
Prostatic Neoplasms
Expression of the p53 and Maspin protein in primary prostate cancer: correlation with clinical features.
Prostatic Neoplasms
Expression of the serine protease kallikrein 7 and its inhibitor antileukoprotease is decreased in prostate cancer.
Prostatic Neoplasms
Frequency of PTEN alterations, TMPRSS2-ERG fusion and their association in prostate cancer.
Prostatic Neoplasms
Genetic upregulation of matriptase-2 reduces the aggressiveness of prostate cancer cells in vitro and in vivo and affects FAK and paxillin localisation.
Prostatic Neoplasms
Gold nanoparticle-based colorimetric method for the detection of prostate-specific antigen.
Prostatic Neoplasms
Hepsin and maspin are inversely expressed in laser capture microdissectioned prostate cancer.
Prostatic Neoplasms
Hepsin immunohistochemical expression in prostate cancer in relation to Gleason's grade and serum prostate specific antigen.
Prostatic Neoplasms
Human kallikrein 2 (hK2), but not prostate-specific antigen (PSA), rapidly complexes with protease inhibitor 6 (PI-6) released from prostate carcinoma cells.
Prostatic Neoplasms
Human prostate cancer and benign prostatic hyperplasia: molecular dissection by gene expression profiling.
Prostatic Neoplasms
Human tissue kallikrein 5 is a member of a proteolytic cascade pathway involved in seminal clot liquefaction and potentially in prostate cancer progression.
Prostatic Neoplasms
Hydrolysis of androgen receptor by cathepsin D: its biological significance in human prostate cancer.
Prostatic Neoplasms
Hypomethylation of urokinase (uPA) promoter in breast and prostate cancer: prognostic and therapeutic implications.
Prostatic Neoplasms
Identification of a novel complex between human kallikrein 2 and protease inhibitor-6 in prostate cancer tissue.
Prostatic Neoplasms
Immunohistochemical Evaluation of ERG Expression in Various Benign and Malignant Tissues.
Prostatic Neoplasms
In vitro and in vivo anticancer action of Saquinavir-NO, a novel nitric oxide-derivative of the protease inhibitor saquinavir, on hormone resistant prostate cancer cells.
Prostatic Neoplasms
In vitro evidence that KLK14 regulates the components of the HGF/Met axis, pro-HGF and HGF-activator inhibitor 1A and 1B.
Prostatic Neoplasms
Increasing C-Terminal Hydrophobicity Improves the Cell Permeability and Antiproliferative Activity of PACE4 Inhibitors against Prostate Cancer Cell Lines.
Prostatic Neoplasms
Induction of the SUMO-specific protease 1 transcription by the androgen receptor in prostate cancer cells.
Prostatic Neoplasms
Inhibition of TMPRSS2 by HAI-2 reduces prostate cancer cell invasion and metastasis.
Prostatic Neoplasms
Inhibition of ubiquitin specific protease 17 restrains prostate cancer proliferation by regulation of epithelial-to-mesenchymal transition (EMT) via ROS production.
Prostatic Neoplasms
Inhibitor-GCPII Interaction: Selective and Robust System for Targeting Cancer Cells with Structurally Diverse Nanoparticles.
Prostatic Neoplasms
Inhibitors of tyrosine kinase inhibit the production of urokinase plasminogen activator in human prostatic cancer cells.
Prostatic Neoplasms
Interaction between Tumor Cell Surface Receptor RAGE and Proteinase 3 Mediates Prostate Cancer Metastasis to Bone.
Prostatic Neoplasms
Interactions and relationships of PTEN, ERG, SPINK1 and AR in castration-resistant prostate cancer.
Prostatic Neoplasms
Interleukin-1? promotes skeletal colonization and progression of metastatic prostate cancer cells with neuroendocrine features.
Prostatic Neoplasms
Intracellular cargo delivery by an octaarginine transporter adapted to target prostate cancer cells through cell surface protease activation.
Prostatic Neoplasms
KLK14 interactions with HAI-1 and HAI-2 serine protease inhibitors: A molecular dynamics and relative free-energy calculations study.
Prostatic Neoplasms
Laminin-332 is a substrate for hepsin, a protease associated with prostate cancer progression.
Prostatic Neoplasms
LONP1 and ClpP cooperatively regulate mitochondrial proteostasis for cancer cell survival.
Prostatic Neoplasms
Loss of Maspin Expression in Bladder Cancer: Its Relationship with p53 and Clinicopathological Parameters.
Prostatic Neoplasms
Loss of the matriptase inhibitor HAI-2 during prostate cancer progression.
Prostatic Neoplasms
Marked heterogeneity of ERG expression in large primary prostate cancers.
Prostatic Neoplasms
Maspin protein expression: a special feature of papillary thyroid carcinoma.
Prostatic Neoplasms
Mastering the canonical loop of serine protease inhibitors: enhancing potency by optimising the internal hydrogen bond network.
Prostatic Neoplasms
Mechanistic insights into the inhibition of prostate specific antigen by beta-lactam class compounds.
Prostatic Neoplasms
Metabolically Stabilized (68)Ga-NOTA-Bombesin for PET Imaging of Prostate Cancer and Influence of Protease Inhibitor Phosphoramidon.
Prostatic Neoplasms
miR-5089-5p suppresses castration-resistant prostate cancer resistance to enzalutamide and metastasis via miR-5089-5p/SPINK1/ MAPK/MMP9 signaling.
Prostatic Neoplasms
Molecular insights into substrate specificity of prostate specific antigen through structural modeling.
Prostatic Neoplasms
Momordin Ic, a new natural SENP1 inhibitor, inhibits prostate cancer cell proliferation.
Prostatic Neoplasms
Murine, but not human, ephrin-B2 can be efficiently cleaved by the serine protease kallikrein-4: Implications for xenograft models of human prostate cancer.
Prostatic Neoplasms
Novel MMP-9 substrates in cancer cells revealed by a label-free quantitative proteomics approach.
Prostatic Neoplasms
Optimization of peptide-based inhibitors of prostate-specific antigen (PSA) as targeted imaging agents for prostate cancer.
Prostatic Neoplasms
Osteoblast-derived TGF-beta1 modulates matrix degrading protease expression and activity in prostate cancer cells.
Prostatic Neoplasms
Osteoblast-derived TGFbeta-1 modulates matrix degrading protease expression and activity in prostate cancer cells
Prostatic Neoplasms
Osteonectin promotes prostate cancer cell migration and invasion: a possible mechanism for metastasis to bone.
Prostatic Neoplasms
Patterns of protease production during prostate cancer progression: proteomic evidence for cascades in a transgenic model.
Prostatic Neoplasms
Pegylated kunitz domain inhibitor suppresses hepsin-mediated invasive tumor growth and metastasis.
Prostatic Neoplasms
Peptide-Nanoparticle Hybrid SERS Probe for Dynamic Detection of Active Cancer Biomarker Enzymes.
Prostatic Neoplasms
Peptide-nanoparticle hybrid SERS probes for optical detection of protease activity.
Prostatic Neoplasms
Potent and selective peptidyl boronic acid inhibitors of the serine protease prostate-specific antigen.
Prostatic Neoplasms
Potent, Selective, and Cell-Penetrating Inhibitors of Kallikrein-Related Peptidase 4 Based on the Cyclic Peptide MCoTI-II.
Prostatic Neoplasms
Powerful Chemiluminescence Probe for Rapid Detection of Prostate Specific Antigen Proteolytic Activity: Forensic Identification of Human Semen.
Prostatic Neoplasms
Preferential production of latent transforming growth factor beta-2 by primary prostatic epithelial cells and its activation by prostate-specific antigen.
Prostatic Neoplasms
Presence and enzymatic activity of prostate-specific antigen in archival prostate cancer samples.
Prostatic Neoplasms
Production and activation of recombinant hK2 with propeptide mutations resulting in high expression levels.
Prostatic Neoplasms
Production of recombinant PSA and HK2 and analysis of their immunologic cross-reactivity.
Prostatic Neoplasms
Profiling of proteolytic activities secreted by cancer cells using phage display substrate technology.
Prostatic Neoplasms
Prognostic impact of SUMO-specific protease 1 (SENP1) in prostate cancer patients undergoing radical prostatectomy.
Prostatic Neoplasms
Prognostic value of ERG, PTEN, CRISP3 and SPINK1 in predicting biochemical recurrence in prostate cancer.
Prostatic Neoplasms
Propapoptotic effects of NF-kappaB in LNCaP prostate cancer cells lead to serine protease activation.
Prostatic Neoplasms
Prostasin serine protease inhibits breast cancer invasiveness and is transcriptionally regulated by promoter DNA methylation.
Prostatic Neoplasms
Prostate cancer cells-osteoblast interaction shifts expression of growth/survival-related genes in prostate cancer and reduces expression of osteoprotegerin in osteoblasts.
Prostatic Neoplasms
Prostate Cancer-Associated Kallikrein-Related Peptidase 4 Activates Matrix Metalloproteinase-1 and Thrombospondin-1.
Prostatic Neoplasms
Prostate specific antigen reduction following statin therapy: Mechanism of action and review of the literature.
Prostatic Neoplasms
Prostate-localized and androgen-regulated expression of the membrane-bound serine protease TMPRSS2.
Prostatic Neoplasms
Prostate-specific antigen and human glandular kallikrein 2 are markedly elevated in urine of patients with polycystic ovary syndrome.
Prostatic Neoplasms
Prostate-specific antigen is a "chymotrypsin-like" serine protease with unique P1 substrate specificity.
Prostatic Neoplasms
Prostate-specific antigen may serve as a pathological predictor in breast cancer.
Prostatic Neoplasms
Prostate-Specific Antigen Modulates Genes Involved in Bone Remodeling and Induces Osteoblast Differentiation of Human Osteosarcoma Cell Line SaOS-2.
Prostatic Neoplasms
Prostate-specific antigen modulates the expression of genes involved in prostate tumor growth.
Prostatic Neoplasms
Prostate-specific antigen modulates the osteogenic differentiation of MSCs via the cadherin 11-Akt axis.
Prostatic Neoplasms
Prostate-specific antigen rising in Iranian men in correlation with body mass index, fasting blood sugar and blood lipid profile.
Prostatic Neoplasms
Prostate-specific antigen, a serine protease, facilitates human prostate cancer cell invasion.
Prostatic Neoplasms
Prostate-specific antigen-activated thapsigargin prodrug as targeted therapy for prostate cancer.
Prostatic Neoplasms
Prostate-specific antigen: an overlooked candidate for the targeted treatment and selective imaging of prostate cancer.
Prostatic Neoplasms
Prostatic human kallikrein 2 inactivates and complexes with plasminogen activator inhibitor-1.
Prostatic Neoplasms
Protease Expression Levels in Prostate Cancer Tissue Can Explain Prostate Cancer-Associated Seminal Biomarkers-An Explorative Concept Study.
Prostatic Neoplasms
Protease nexin 1 induces apoptosis of prostate tumor cells through inhibition of X-chromosome-linked inhibitor of apoptosis protein.
Prostatic Neoplasms
Protease nexin 1: a novel regulator of prostate cancer cell growth and neo-angiogenesis.
Prostatic Neoplasms
Proteasome-associated deubiquitinase ubiquitin-specific protease 14 regulates prostate cancer proliferation by deubiquitinating and stabilizing androgen receptor.
Prostatic Neoplasms
Protection of prostatic acid phosphatase activity in human serum samples by plasmin inhibitors.
Prostatic Neoplasms
Protein C inhibitor (plasminogen activator inhibitor-3) expression in the CWR22 prostate cancer xenograft.
Prostatic Neoplasms
PSA affects prostate cancer cell invasion in vitro and induces an osteoblastic phenotype in bone in vivo.
Prostatic Neoplasms
PSA-alpha-2-macroglobulin complex is enzymatically active in the serum of patients with advanced prostate cancer and can degrade circulating peptide hormones.
Prostatic Neoplasms
Quantitative proteomic analysis of proteins released by neoplastic prostate epithelium.
Prostatic Neoplasms
Quercetin inhibits invasion, migration and signalling molecules involved in cell survival and proliferation of prostate cancer cell line (PC-3).
Prostatic Neoplasms
Re: Classification of Prostate Cancer Using a Protease Activity Nanosensor Library.
Prostatic Neoplasms
Recombinant prostate specific antigen inhibits angiogenesis in vitro and in vivo.
Prostatic Neoplasms
Regulation of the enzymatic activity of prostate-specific antigen and its reactions with extracellular protease inhibitors in prostate cancer.
Prostatic Neoplasms
Regulation of urokinase production by androgens in human prostate cancer cells: effect on tumor growth and metastases in vivo.
Prostatic Neoplasms
Related Endogenous Retrovirus-K Elements Harbor Distinct Protease Active Site Motifs.
Prostatic Neoplasms
Reverse biochemistry: use of macromolecular protease inhibitors to dissect complex biological processes and identify a membrane-type serine protease in epithelial cancer and normal tissue.
Prostatic Neoplasms
Role of cathepsin D in prostatic cancer cell growth and its regulation by brefeldin A.
Prostatic Neoplasms
Role of urokinase (uPA) and its receptor (uPAR) in invasion and metastasis of hormone-dependent malignancies.
Prostatic Neoplasms
Screening a combinatorial peptide library to develop a human glandular kallikrein 2-activated prodrug as targeted therapy for prostate cancer.
Prostatic Neoplasms
Screening strategy of TMPRSS2 inhibitors by FRET-based enzymatic activity for TMPRSS2-based cancer and COVID-19 treatment.
Prostatic Neoplasms
Secretory leukocyte protease inhibitor is a survival and proliferation factor for castration-resistant prostate cancer.
Prostatic Neoplasms
Seminal fluid characterization for male fertility and prostate cancer: kallikrein-related serine proteases and whole proteome approaches.
Prostatic Neoplasms
SENP1 induces prostatic intraepithelial neoplasia through multiple mechanisms.
Prostatic Neoplasms
Separation of enzymatically active and inactive prostate-specific antigen (PSA) by peptide affinity chromatography.
Prostatic Neoplasms
Serine protease inhibitor Kazal type 1 promotes epithelial-mesenchymal transition through EGFR signaling pathway in prostate cancer.
Prostatic Neoplasms
Serum human glandular kallikrein-2 protease levels predict the presence of prostate cancer among men with elevated prostate-specific antigen.
Prostatic Neoplasms
Serum total and free prostate-specific antigen for breast cancer diagnosis in women.
Prostatic Neoplasms
Snail transcription factor NLS and importin ?1 regulate the subcellular localization of Cathepsin L and Cux1.
Prostatic Neoplasms
Specific and efficient peptide substrates for assaying the proteolytic activity of prostate-specific antigen.
Prostatic Neoplasms
Stability of total prostate-specific antigen and free prostate-specific antigen after 10 years' storage.
Prostatic Neoplasms
Steam heat with an EDTA buffer and protease digestion optimizes immunohistochemical expression of basal cell-specific antikeratin 34betaE12 to discriminate cancer in prostatic epithelium.
Prostatic Neoplasms
Structural basis of ubiquitin recognition by the deubiquitinating protease USP2.
Prostatic Neoplasms
Structural optimization, biological evaluation, and application of peptidomimetic prostate specific antigen inhibitors.
Prostatic Neoplasms
Substrate-guided design of a potent and selective kallikrein-related peptidase inhibitor for kallikrein 4.
Prostatic Neoplasms
Synergistic tumor growth-inhibitory effect of the prostate-specific antigen-activated fusion peptide BSD352 for prostate cancer therapy.
Prostatic Neoplasms
Synthesis of thiophene-2-carboxamidines containing 2-aminothiazoles and their biological evaluation as urokinase inhibitors.
Prostatic Neoplasms
Tannic acid suppresses SARS-CoV-2 as a dual inhibitor of the viral main protease and the cellular TMPRSS2 protease.
Prostatic Neoplasms
Targeted inhibition of cell-surface serine protease Hepsin blocks prostate cancer bone metastasis.
Prostatic Neoplasms
Testosterone and prostate specific antigen stimulate generation of reactive oxygen species in prostate cancer cells.
Prostatic Neoplasms
Tfs1p, a member of the PEBP family, inhibits the Ira2p but not the Ira1p Ras GTPase-activating protein in Saccharomyces cerevisiae.
Prostatic Neoplasms
The androgen-regulated protease TMPRSS2 activates a proteolytic cascade involving components of the tumor microenvironment and promotes prostate cancer metastasis.
Prostatic Neoplasms
The androgen-regulated type II serine protease TMPRSS2 is differentially expressed and mislocalized in prostate adenocarcinoma.
Prostatic Neoplasms
The human immunodeficiency virus (HIV)-1 protease inhibitor saquinavir inhibits proteasome function and causes apoptosis and radiosensitization in non-HIV-associated human cancer cells.
Prostatic Neoplasms
The impaired viability of prostate cancer cell lines by the recombinant plant kallikrein inhibitor.
Prostatic Neoplasms
The induction of Maspin expression by a glucosamine-derivative has an antiproliferative activity in prostate cancer cell lines.
Prostatic Neoplasms
The Kunitz Domain I of Hepatocyte Growth Factor Activator Inhibitor-2 Inhibits Matriptase Activity and Invasive Ability of Human Prostate Cancer Cells.
Prostatic Neoplasms
The mediating role of caspase-3 protease in the intracellular mechanism of genistein-induced apoptosis in human prostatic carcinoma cell lines, DU145 and LNCaP.
Prostatic Neoplasms
The membrane-anchored serine protease, TMPRSS2, activates PAR-2 in prostate cancer cells.
Prostatic Neoplasms
The Role of Biomarkers and Genetics in the Diagnosis of Prostate Cancer.
Prostatic Neoplasms
The SERCA pump as a therapeutic target: making a "smart bomb" for prostate cancer.
Prostatic Neoplasms
The surface of prostate carcinoma DU145 cells mediates the inhibition of urokinase-type plasminogen activator by maspin.
Prostatic Neoplasms
The TMPRSS2 gene encoding transmembrane serine protease is overexpressed in a majority of prostate cancer patients: detection of mutated TMPRSS2 form in a case of aggressive disease.
Prostatic Neoplasms
The Transcription Factor ERG Regulates Super-Enhancers Associated With an Endothelial-Specific Gene Expression Program.
Prostatic Neoplasms
Thiophilic-interaction chromatography of enzymatically active tissue prostate-specific antigen (T-PSA) and its modulation by zinc ions.
Prostatic Neoplasms
Thrombin/thrombin receptor (PAR-1)-mediated induction of IL-8 and VEGF expression in prostate cancer cells.
Prostatic Neoplasms
Timp3 loss accelerates tumour invasion and increases prostate inflammation in a mouse model of prostate cancer.
Prostatic Neoplasms
TMPRSS2, a Serine Protease Expressed in the Prostate on the Apical Surface of Luminal Epithelial Cells and Released into Semen in Prostasomes, Is Misregulated in Prostate Cancer Cells.
Prostatic Neoplasms
Treatment with soybean-derived Bowman Birk inhibitor increases serum prostate-specific antigen concentration while suppressing growth of human prostate cancer xenografts in nude mice.
Prostatic Neoplasms
Trp(250) -hK2 is defective in intracellular trafficking and activates the unfolded protein response.
Prostatic Neoplasms
Trypsin-like proteolytic contamination of commercially available psa purified from human seminal fluid.
Prostatic Neoplasms
Tumor-suppressive maspin regulates cell response to oxidative stress by direct interaction with glutathione S-transferase.
Prostatic Neoplasms
Tumor-suppressive microRNA-145 induces growth arrest by targeting SENP1 in human prostate cancer cells.
Prostatic Neoplasms
Ubiquitin-specific protease 12 interacting partners Uaf-1 and WDR20 are potential therapeutic targets in prostate cancer.
Prostatic Neoplasms
Ubiquitin-specific protease 14 promotes prostate cancer progression through deubiquitinating the transcriptional factor ATF2.
Prostatic Neoplasms
Urinary biomarkers in prostate cancer detection and monitoring progression.
Prostatic Neoplasms
Urokinase plasminogen activator is necessary but not sufficient for prostate cancer cell invasion.
Prostatic Neoplasms
Urokinase-mediated extracellular matrix degradation by human prostatic carcinoma cells and its inhibition by retinoic acid.
Prostatic Neoplasms
Variants in the HEPSIN gene are associated with prostate cancer in men of European origin.
Prostatic Neoplasms
White Button Mushroom (Agaricus bisporus) Interrupts Tissue AR-TMPRSS2 Expression and Attenuates Pro-inflammatory Cytokines in C57BL/6 Mice: Implication for COVID-19 Dietary Intervention.
Prostatic Neoplasms
White button mushroom interrupts tissue AR-mediated TMPRSS2 expression and attenuates pro-inflammatory cytokines in C57BL/6 mice.
Prostatic Neoplasms
Whole-transcriptome analysis reveals established and novel associations with TMPRSS2:ERG fusion in prostate cancer.
Prostatic Neoplasms
[Correlation of prostate-specific antigen with the progression and metastasis of human prostate cancer].
Prostatic Neoplasms
[Research on the structure of the PSA promoter and the mechanisms of its expression regulation.]
Prostatitis
Neonatal exposure to 2,3,7,8-tetrachlorodibenze-p-dioxin increases the mRNA expression of prostatic proteins in C57BL mice.
Protein C Deficiency
A molecular model of the serine protease domain of activated protein C: application to the study of missense mutations causing protein C deficiency.
Protein C Deficiency
Hereditary thrombophilia: identification of nonsense and missense mutations in the protein C gene.
Protein C Deficiency
Rapid detection of a protein C gene mutation present in the asymptomatic and not in the thrombosis-prone lineage.
Protein C Deficiency
Six missense mutations associated with type I and type II protein C deficiency and implications obtained from molecular modelling.
Protein Deficiency
Activation of protease activity in rat peritoneal macrophages in protein deficiency: characterization of cathepsin D.
Protein Deficiency
Differential expression of genes in fetal brain as a consequence of maternal protein deficiency and nematode infection.
Protein Deficiency
Downregulation of mitochondrial lon protease impairs mitochondrial function and causes hepatic insulin resistance in human liver SK-HEP-1 cells.
Protein Deficiency
New therapeutics in C1INH deficiency: a review of recent studies and advances.
Protein Deficiency
The ultrastructure of skeletal and smooth muscle in experimental protein malnutrition in rats fed a low protein diet.
Protein Deficiency
What can be learned in the snake antivenom field from the developments in human plasma derived products?
protein disulfide-isomerase deficiency
Lung vascular injury with protease infusion. Relationship to plasma fibronectin.
Protein S Deficiency
Familial thrombophilia due to a previously unrecognized mechanism characterized by poor anticoagulant response to activated protein C: prediction of a cofactor to activated protein C.
protein-glutamine gamma-glutamyltransferase deficiency
Bleeding disorder with abnormal wound healing, acid-soluble clots and normal factor XIII.
Proteinuria
A serine protease inhibitor camostat mesilate prevents podocyte apoptosis and attenuates podocyte injury in metabolic syndrome model rats.
Proteinuria
Aberrant glomerular filtration of urokinase-type plasminogen activator in nephrotic syndrome leads to amiloride-sensitive plasminogen activation in urine.
Proteinuria
Antithrombin III prevents blood pressure elevation and proteinuria induced by high salt intake in pregnant stroke-prone spontaneously hypertensive rats.
Proteinuria
Aprotinin prevents proteolytic epithelial sodium channel (ENaC) activation and volume retention in nephrotic syndrome.
Proteinuria
Effect of camostat mesilate on urinary protein excretion in three patients with advanced diabetic nephropathy.
Proteinuria
Enzymolysis of glomerular immune deposits in vivo with dextranase/protease ameliorates proteinuria, hematuria, and mesangial proliferation in murine experimental IgA nephropathy.
Proteinuria
Impact of protease inhibitors on the evolution of urinary markers: Subanalyses from an observational cross-sectional study.
Proteinuria
Induction of Nephrotic Syndrome in Mice by Retrobulbar Injection of Doxorubicin and Prevention of Volume Retention by Sustained Release Aprotinin.
Proteinuria
Long-term kidney function, proteinuria, and associated risks among HIV-infected and uninfected men.
Proteinuria
Prevalence of renal disease within an urban HIV-infected cohort in northern Italy.
Proteinuria
Reduced Lon protease 1 expression in podocytes contributes to the pathogenesis of podocytopathy.
Proteinuria
Tenofovir use and urinary biomarkers among HIV-infected women in the Women's Interagency HIV Study (WIHS).
Proteinuria
Upregulation of the immunoproteasome in peripheral blood mononuclear cells of patients with IgA nephropathy.
Proteinuria
Urine protease and antiprotease activity in experimental aminonucleoside nephrotoxicity.
Proteinuria
Urine proteome scans uncover total urinary protease, prostaglandin D synthase, serum amyloid P, and superoxide dismutase as potential markers of lupus nephritis.
Pruritus
Double-Blind, Randomized, Pilot Study Assessing the Resolution of Postburn Pruritus.
Pruritus
Epidermal Proteinase-Activated Receptor-2 Expression is Increased in End-Stage Renal Disease Patients with Pruritus: A Pilot Study.
Pruritus
How best to fight that nasty itch - from new insights into the neuroimmunological, neuroendocrine, and neurophysiological bases of pruritus to novel therapeutic approaches.
Pruritus
Involvement of serine protease and proteinase-activated receptor 2 in dermatophyte-associated itch in mice.
Pruritus
Mechanisms of itching in mycosis fungoides: grade of itching correlates with eosinophil infiltration and kallikrein 5 expression.
Pruritus
The Importance of Acidification in Atopic Eczema: An Underexplored Avenue for Treatment.
Pseudomonas Infections
A secretory leukocyte protease inhibitor variant with improved activity against lung infection.
Pseudomonas Infections
Assessment of protease (elastase) as a Pseudomonas aeruginosa virulence factor in experimental mouse burn infection.
Pseudomonas Infections
Effects of immunization of horses with common antigen (OEP), protease toxoid, and elastase toxoid on corneal ulceration due to Pseudomonas aeruginosa infection.
Pseudomonas Infections
Effects of zinc sulfate on Pseudomonas aeruginosa infections and protease in rabbit corneas.
Pseudomonas Infections
Experimental studies of the pathogenesis of infections due to Pseudomonas aeruginosa: effect of treatment with protease inhibitors.
Pseudomonas Infections
Specific protease activity indicates the degree of Pseudomonas aeruginosa infection in chronic infected wounds.
Pseudomonas Infections
Therapeutic effect of immunization with OEP, protease toxoid and elastase toxoid on corneal ulcers in mice due to Pseudomonas aeruginosa infection.
Pseudomonas Infections
Virulence factors are released from Pseudomonas aeruginosa in association with membrane vesicles during normal growth and exposure to gentamicin: a novel mechanism of enzyme secretion.
Pseudorabies
Correction: Dimerization-Induced Allosteric Changes of the Oxyanion-Hole Loop Activate the Pseudorabies Virus Assemblin pUL26N, a Herpesvirus Serine Protease.
Pseudorabies
Dimerization-Induced Allosteric Changes of the Oxyanion-Hole Loop Activate the Pseudorabies Virus Assemblin pUL26N, a Herpesvirus Serine Protease.
Pseudorabies
Mutagenesis of the active-site cysteine in the ubiquitin-specific protease contained in large tegument protein pUL36 of pseudorabies virus impairs viral replication in vitro and neuroinvasion in vivo.
Pseudorabies
Proteolytic cleavage of glycoprotein B is dispensable for in vitro replication, but required for syncytium formation of pseudorabies virus.
Pseudorabies
The export pathway of the pseudorabies virus gB homolog gII involves oligomer formation in the endoplasmic reticulum and protease processing in the Golgi apparatus.
Pseudoxanthoma Elasticum
Elastase-like protease and elastolytic activities expressed in cultured dermal fibroblasts derived from lesional skin of patients with pseudoxanthoma elasticum, actinic elastosis, and cutis laxa.
Pseudoxanthoma Elasticum
Evidence for increased protease activity secreted from cultured fibroblasts from patients with pseudoxanthoma elasticum.
Psoriasis
Altered insulin-like growth factor-II (IGF-II) level and IGF-binding protein-3 (IGFBP-3) protease activity in interstitial fluid taken from the skin lesion of psoriasis.
Psoriasis
Association of osteoarthritis with homozygosity for a 5.8 kb Taq I fragment of the alpha 1-antichymotrypsin gene.
Psoriasis
Down-regulation of tissue levels of serine protease inhibitor (vaspin) in psoriasis vulgaris patients: a possible mechanism of narrowband ultraviolet B radiation.
Psoriasis
Generation of recombinant antibodies against human tissue kallikrein 7 to treat skin diseases.
Psoriasis
GLS1-mediated glutaminolysis unbridled by MALT1 protease promotes psoriasis pathogenesis.
Psoriasis
Human skin proteases. Fractionation of psoriasis scale proteases and separation of a plasminogen activator and a histone hydrolysing protease.
Psoriasis
Increased plasma concentrations of cytoskeletal and Ca2+-binding proteins and their peptides in psoriasis patients.
Psoriasis
Influence of skin penetration enhancers on skin barrier function and skin protease activity.
Psoriasis
Sequence, organization, chromosomal localization, and alternative splicing of the human serine protease inhibitor gene hurpin (PI13) which is upregulated in psoriasis.
Psoriasis
SERPINB3/B4 contributes to early inflammation and barrier dysfunction in an experimental murine model of atopic dermatitis.
Psoriasis
The serine protease marapsin is expressed in stratified squamous epithelia and is up-regulated in the hyperproliferative epidermis of psoriasis and regenerating wounds.
Pterygium
Ultraviolet-A irradiation upregulated urokinase-type plasminogen activator in pterygium fibroblasts through ERK and JNK pathways.
Pterygium
UVB-elicited induction of MMP-1 expression in human ocular surface epithelial cells is mediated through the ERK1/2 MAPK-dependent pathway.
Puberty, Precocious
Serum concentrations of free and total insulin-like growth factor-I, IGF binding proteins -1 and -3 and IGFBP-3 protease activity in boys with normal or precocious puberty.
Puerperal Infection
Protease production by microorganisms associated with reproductive tract infection.
Pulmonary Arterial Hypertension
Pharmacokinetics and pharmacodynamics of sildenafil in a patient treated with human immunodeficiency virus protease inhibitors.
Pulmonary Arterial Hypertension
Sildenafil and bosentan plasma concentrations in a human immunodeficiency virus- infected patient with pulmonary arterial hypertension treated with ritonavir-boosted protease inhibitor.
Pulmonary Arterial Hypertension
Visceral adipose tissue-derived serine protease inhibitor prevents the development of monocrotaline-induced pulmonary arterial hypertension in rats.
Pulmonary Disease, Chronic Obstructive
A Mitochondrial Perspective of Chronic Obstructive Pulmonary Disease Pathogenesis.
Pulmonary Disease, Chronic Obstructive
A Randomised, Placebo-Controlled, Dose-Finding Study Of AZD9668, An Oral Inhibitor of Neutrophil Elastase, in Patients with Chronic Obstructive Pulmonary Disease Treated with Tiotropium.
Pulmonary Disease, Chronic Obstructive
A randomised, placebo-controlled, dose-finding study of AZD9668, an oral inhibitor of neutrophil elastase, in patients with chronic obstructive pulmonary disease treated with tiotropium.
Pulmonary Disease, Chronic Obstructive
Absence of association between SERPINE2 genetic polymorphisms and chronic obstructive pulmonary disease in Han Chinese: a case-control cohort study.
Pulmonary Disease, Chronic Obstructive
ADAM17 Deficiency Protects against Pulmonary Emphysema.
Pulmonary Disease, Chronic Obstructive
Adenoviral E1A suppresses secretory leukoprotease inhibitor and elafin secretion in human alveolar epithelial cells and bronchial epithelial cells.
Pulmonary Disease, Chronic Obstructive
Airway Resistance Caused by Sphingomyelin Synthase 2 Insufficiency in Response to Cigarette Smoke.
Pulmonary Disease, Chronic Obstructive
All-trans retinoic acid modulates the balance of matrix metalloproteinase-9 and tissue inhibitor of metalloproteinase-1 in patients with emphysema.
Pulmonary Disease, Chronic Obstructive
Alpha-1-antitrypsin deficiency in the Cape Verde islands (Northwest Africa): High prevalence in a sub-Saharan population.
Pulmonary Disease, Chronic Obstructive
Altered protease and antiprotease balance during a COPD exacerbation contributes to mucus obstruction.
Pulmonary Disease, Chronic Obstructive
Anti-inflammatory activity of neutrophil elastase inhibitors.
Pulmonary Disease, Chronic Obstructive
Antimicrobial Peptides SLPI and Beta Defensin-1 in Sputum are Negatively Correlated with FEV1.
Pulmonary Disease, Chronic Obstructive
Attacking the multi-tiered proteolytic pathology of COPD: new insights from basic and translational studies.
Pulmonary Disease, Chronic Obstructive
Cathepsin G degradation of phospholipid transfer protein (PLTP) augments pulmonary inflammation.
Pulmonary Disease, Chronic Obstructive
Cellular Signaling Crosstalk Between Multiple Receptors for Investigation of Pathophysiology in Multifactorial Diseases - What is Clinically-Relevant Crosstalk?
Pulmonary Disease, Chronic Obstructive
Characterisation of urokinase plasminogen activator receptor variants in human airway and peripheral cells.
Pulmonary Disease, Chronic Obstructive
Chronic obstructive pulmonary disease in alpha1-antitrypsin PI MZ heterozygotes: a meta-analysis.
Pulmonary Disease, Chronic Obstructive
Cigarette smoke extract-treated mast cells promote alveolar macrophage infiltration and polarization in experimental chronic obstructive pulmonary disease.
Pulmonary Disease, Chronic Obstructive
Cleavage of CXCR1 on neutrophils disables bacterial killing in cystic fibrosis lung disease.
Pulmonary Disease, Chronic Obstructive
Clickable 4-Oxo-?-lactam-Based Selective Probing for Human Neutrophil Elastase Related Proteomes.
Pulmonary Disease, Chronic Obstructive
Comparative proteome analysis of peripheral neutrophils from sulfur mustard-exposed and COPD patients.
Pulmonary Disease, Chronic Obstructive
Cytokine and chemokine expression in cigarette smoke-induced lung injury in guinea pigs.
Pulmonary Disease, Chronic Obstructive
Detection of an alteration of the alpha 2-macroglobulin gene in a patient with chronic lung disease and serum alpha 2-macroglobulin deficiency.
Pulmonary Disease, Chronic Obstructive
Development of predictive models for airflow obstruction in alpha-1-antitrypsin deficiency.
Pulmonary Disease, Chronic Obstructive
Does Protease-Antiprotease Imbalance Explain Chronic Obstructive Pulmonary Disease?
Pulmonary Disease, Chronic Obstructive
Double deficiency of tetraspanins CD9 and CD81 Alters cell motility and protease production of macrophages and causes chronic obstructive pulmonary disease-like phenotype in mice.
Pulmonary Disease, Chronic Obstructive
Dual function inhibitors of relevance to chronic obstructive pulmonary disease.
Pulmonary Disease, Chronic Obstructive
Dysregulation of COVID-19 related gene expression in the COPD lung.
Pulmonary Disease, Chronic Obstructive
Effect of corticosteroids on sputum sol-phase protease inhibitors in chronic obstructive pulmonary disease.
Pulmonary Disease, Chronic Obstructive
Effect of Oxidative Stress on Diaphragm Dysfunction and Exercise Intervention in Chronic Obstructive Pulmonary Disease.
Pulmonary Disease, Chronic Obstructive
Effect of Pingchuan Guben decoction on patients with chronic obstructive pulmonary disease: Results from a randomized comparative effectiveness research trial.
Pulmonary Disease, Chronic Obstructive
Effects of neuromuscular electrical stimulation on pulmonary alveola and cytokines in chronic obstructive pulmonary disease (COPD) and skeletal muscle atrophy model mice.
Pulmonary Disease, Chronic Obstructive
Efficient inhibition of human leukocytic elastase by means of ?1 -antitrypsin/peptide complexes.
Pulmonary Disease, Chronic Obstructive
Emerging drugs for chronic obstructive pulmonary disease.
Pulmonary Disease, Chronic Obstructive
Emerging role of MAP kinase pathways as therapeutic targets in COPD.
Pulmonary Disease, Chronic Obstructive
Environmental and genetic risk factors and gene-environment interactions in the pathogenesis of chronic obstructive lung disease.
Pulmonary Disease, Chronic Obstructive
Exogenous neutrophil elastase enters bronchial epithelial cells and suppresses cigarette smoke extract-induced heme oxygenase-1 by cleaving sirtuin 1.
Pulmonary Disease, Chronic Obstructive
Experimental Pneumocystis lung infection promotes M2a alveolar macrophage-derived MMP12 production.
Pulmonary Disease, Chronic Obstructive
Familial aggregation of abnormal ventilatory control and pulmonary function in chronic obstructive pulmonary disease.
Pulmonary Disease, Chronic Obstructive
Familial variation of leukocyte lysosomal protease and serum 1 -antitrypsin as determinants in chronic obstructive pulmonary disease.
Pulmonary Disease, Chronic Obstructive
Functions of NQO1 in Cellular Protection and CoQ10 Metabolism and its Potential Role as a Redox Sensitive Molecular Switch.
Pulmonary Disease, Chronic Obstructive
Gene-Gene Interactions Between Glutathione S-Transferase M1 and Matrix Metalloproteinases 1, 9, and 12 in Chronic Obstructive Pulmonary Disease in Serbians.
Pulmonary Disease, Chronic Obstructive
Granulocyte/macrophage-colony-stimulating factor (GM-CSF) regulates lung innate immunity to lipopolysaccharide through Akt/Erk activation of NFkappa B and AP-1 in vivo.
Pulmonary Disease, Chronic Obstructive
Haplotype in SERPINA1 (AAT) Is Associated with Reduced Risk for COPD in a Mexican Mestizo Population.
Pulmonary Disease, Chronic Obstructive
Heterozygous Genotype rs17580 AT (PiS) in SERPINA1 is Associated with COPD Secondary to Biomass-Burning and Tobacco Smoking: A Case-Control and Populational Study.
Pulmonary Disease, Chronic Obstructive
High Serum Level of IL-17 in Patients with Chronic Obstructive Pulmonary Disease and the Alpha-1 Antitrypsin PiZ Allele.
Pulmonary Disease, Chronic Obstructive
High-resolution ex vivo NMR spectroscopy of human Z ?1-antitrypsin.
Pulmonary Disease, Chronic Obstructive
Identification and characterisation of the major antiproteases in equine serum and an investigation of their role in the onset of chronic obstructive pulmonary disease (COPD).
Pulmonary Disease, Chronic Obstructive
IL-1R1/MyD88 signaling is critical for elastase-induced lung inflammation and emphysema.
Pulmonary Disease, Chronic Obstructive
Immune-mediated inflammation in the pathogenesis of emphysema: insights from mouse models.
Pulmonary Disease, Chronic Obstructive
Inhibition of the protease activity in tracheobronchial aspirates of horses with chronic obstructive pulmonary disease.
Pulmonary Disease, Chronic Obstructive
Innate immunity proteins in chronic obstructive pulmonary disease and idiopathic pulmonary fibrosis.
Pulmonary Disease, Chronic Obstructive
Interrelationships between neutrophil elastase, serum alpha, -antitrypsin, lung function and chest radiography in patients with chronic airflow obstruction.
Pulmonary Disease, Chronic Obstructive
Letter: Familial variation of leukocyte lysosomal protease and serum alpha 1-antitrypsin as determinants in chronic obstructive pulmonary disease.
Pulmonary Disease, Chronic Obstructive
Letter: Familial variation of leukocyte lysosomal protease and serum alpha 1-antitrypsin as determinants in chronic obstructive pulmonary diseases.
Pulmonary Disease, Chronic Obstructive
Lung tissue destruction by proteinase 3 and cathepsin G mediated elastin degradation is elevated in chronic obstructive pulmonary disease.
Pulmonary Disease, Chronic Obstructive
N-Arylacyl O-sulfonated aminoglycosides as novel inhibitors of human neutrophil elastase, cathepsin G and proteinase 3.
Pulmonary Disease, Chronic Obstructive
Neutrophil elastase increases MUC4 expression in normal human bronchial epithelial cells.
Pulmonary Disease, Chronic Obstructive
Neutrophil elastase inhibitors: recent advances in the development of mechanism-based and nonelectrophilic inhibitors.
Pulmonary Disease, Chronic Obstructive
Neutrophilic inflammation and IL-8 levels in induced sputum of alpha-1-antitrypsin PiMZ subjects.
Pulmonary Disease, Chronic Obstructive
New treatments for chronic obstructive pulmonary disease and viable formulation/device options for inhalation therapy.
Pulmonary Disease, Chronic Obstructive
Novel drug targets for asthma and COPD: Lessons learned from in vitro and in vivo models.
Pulmonary Disease, Chronic Obstructive
Novel RNA-binding activity of NQO1 promotes SERPINA1 mRNA translation.
Pulmonary Disease, Chronic Obstructive
Pathogenesis of COPD. Part I. The role of protease-antiprotease imbalance in emphysema.
Pulmonary Disease, Chronic Obstructive
PDE4 inhibitors as potential therapeutic agents in the treatment of COPD-focus on roflumilast.
Pulmonary Disease, Chronic Obstructive
PI SZ phenotype in chronic obstructive pulmonary disease.
Pulmonary Disease, Chronic Obstructive
Pine bark extract (Pycnogenol®) suppresses cigarette smoke-induced fibrotic response via transforming growth factor-?1/Smad family member 2/3 signaling.
Pulmonary Disease, Chronic Obstructive
Plasma levels of alpha1-antichymotrypsin and secretory leukocyte proteinase inhibitor in healthy and chronic obstructive pulmonary disease (COPD) subjects with and without severe alpha1-antitrypsin deficiency.
Pulmonary Disease, Chronic Obstructive
Prevalence of ?1-antitrypsin PiZZ genotypes in patients with COPD in Europe: a systematic review.
Pulmonary Disease, Chronic Obstructive
Prevalence of abnormal protease inhibitor phenotypes in patients with chronic obstructive lung disease.
Pulmonary Disease, Chronic Obstructive
Protease inhibitor phenotypes and serum alpha-1-antitrypsin levels in patients with COPD: a study from Hong Kong.
Pulmonary Disease, Chronic Obstructive
Protease inhibitors in chronic obstructive pulmonary disease.
Pulmonary Disease, Chronic Obstructive
Protease inhibitors in patients with chronic obstructive pulmonary disease: the alpha-antitrypsin heterozygote controversy.
Pulmonary Disease, Chronic Obstructive
Protease inhibitors in respiratory disease: focus on asthma and chronic obstructive pulmonary disease.
Pulmonary Disease, Chronic Obstructive
Protease injury in the development of COPD: Thomas A. Neff Lecture.
Pulmonary Disease, Chronic Obstructive
Proteases and protease inhibitors in chronic obstructive lung disease.
Pulmonary Disease, Chronic Obstructive
Proteases and Their Inhibitors in Chronic Obstructive Pulmonary Disease.
Pulmonary Disease, Chronic Obstructive
Proteases, Mucus, and Mucosal Immunity in Chronic Lung Disease.
Pulmonary Disease, Chronic Obstructive
Protection of alpha-1 protease inhibitor by plasma antioxidants. Potential abnormality in chronic obstructive pulmonary disease (COPD).
Pulmonary Disease, Chronic Obstructive
Quantification and evaluation of the role of antielastin autoantibodies in the emphysematous lung.
Pulmonary Disease, Chronic Obstructive
Real time PCR detection of the PI*Z and PI*S mutations associated with alpha-1 antitrypsin deficiency.
Pulmonary Disease, Chronic Obstructive
Respiratory failure associated with the lipodystrophy syndrome in an HIV-positive patient with compromised lung function.
Pulmonary Disease, Chronic Obstructive
Review of the association between periodontitis and chronic obstructive pulmonary disease in smokers.
Pulmonary Disease, Chronic Obstructive
Risk factors for reduced pulmonary function in women. A possible relationship between Pi phenotype, number of children, and pulmonary function.
Pulmonary Disease, Chronic Obstructive
Role of Proteases in Chronic Obstructive Pulmonary Disease.
Pulmonary Disease, Chronic Obstructive
Secretory leucocyte protease inhibitor inhibits interferon-gamma-induced cathepsin S expression.
Pulmonary Disease, Chronic Obstructive
Serine Protease Imbalance in the Small Airways and Development of Centrilobular Emphysema in COPD.
Pulmonary Disease, Chronic Obstructive
Serpine2 deficiency results in lung lymphocyte accumulation and bronchus-associated lymphoid tissue formation.
Pulmonary Disease, Chronic Obstructive
SERPINE2 rs16865421 polymorphism is associated with a lower risk of chronic obstructive pulmonary disease in the Uygur population: A case-control study.
Pulmonary Disease, Chronic Obstructive
Serum and bronchial lavage fluid concentrations of IL-8, SLPI, sCD14 and sICAM-1 in patients with COPD and asthma.
Pulmonary Disease, Chronic Obstructive
Stem cell therapy in chronic obstructive pulmonary disease. Seeking the prometheus effect.
Pulmonary Disease, Chronic Obstructive
Synergistic cycles of protease activity and inflammation via PPAR? degradation in chronic obstructive pulmonary disease.
Pulmonary Disease, Chronic Obstructive
Synthesis and evaluation of silanediols as highly selective uncompetitive inhibitors of human neutrophil elastase.
Pulmonary Disease, Chronic Obstructive
Systemic cytokines, clinical and physiological changes in patients hospitalized for exacerbation of COPD.
Pulmonary Disease, Chronic Obstructive
TAILS proteomics reveals dynamic changes in airway proteolysis controlling protease activity and innate immunity during COPD exacerbations.
Pulmonary Disease, Chronic Obstructive
Targeted Treatments for Chronic Obstructive Pulmonary Disease (COPD) Using Low-Molecular-Weight Drugs (LMWDs).
Pulmonary Disease, Chronic Obstructive
Targeting COPD: Advances on low-molecular-weight inhibitors of human neutrophil elastase.
Pulmonary Disease, Chronic Obstructive
Ten-year changes of protease inhibitors in the sons of patients with COPD.
Pulmonary Disease, Chronic Obstructive
TGF-?1 Impairs Vitamin D-Induced and Constitutive Airway Epithelial Host Defense Mechanisms.
Pulmonary Disease, Chronic Obstructive
The correlation of age and body mass index with the level of both protease MMP3 and anti-protease TIMP-1 among Indonesian patients with chronic obstructive pulmonary disease: a preliminary findings.
Pulmonary Disease, Chronic Obstructive
The Impact of Lung Proteases on Snake-Derived Antimicrobial Peptides.
Pulmonary Disease, Chronic Obstructive
The protease inhibitor PI*S allele and COPD: a meta-analysis.
Pulmonary Disease, Chronic Obstructive
The Role of Computed Tomography for the Evaluation of Lung Disease in Alpha-1 Antitrypsin Deficiency.
Pulmonary Disease, Chronic Obstructive
The roles of inflammatory cells in the pathogenesis of asthma and of chronic obstructive pulmonary disease.
Pulmonary Disease, Chronic Obstructive
The Serpin Superfamily and Their Role in the Regulation and Dysfunction of Serine Protease Activity in COPD and Other Chronic Lung Diseases.
Pulmonary Disease, Chronic Obstructive
Therapeutic potential of alpha-1 antitrypsin in human disease.
Pulmonary Disease, Chronic Obstructive
TLR4 Protein Contributes to Cigarette Smoke-induced Matrix Metalloproteinase-1 (MMP-1) Expression in Chronic Obstructive Pulmonary Disease.
Pulmonary Disease, Chronic Obstructive
Unexpected active-site flexibility in the structure of human neutrophil elastase in complex with a new dihydropyrimidone inhibitor.
Pulmonary Disease, Chronic Obstructive
Untangling the protease web in COPD: metalloproteinases in the silent zone.
Pulmonary Disease, Chronic Obstructive
[Alpha 1-antitrypsin deficiency: a review with special reference to the significance of heterozygous deficiency]
Pulmonary Disease, Chronic Obstructive
[Clinical significance of fibronectin and protease inhibitors in chronic obstructive pulmonary diseases]
Pulmonary Disease, Chronic Obstructive
[Correlations between chymase activity ,levels of tryptase, and eotaxin in the sputum of patients with chronic obstructive puhnonary disease and their clinical implications]
Pulmonary Disease, Chronic Obstructive
[Effect of the protease inhibitor aprotinin on pulmonary function and on the inhibitory activity of sputum in patients with chronic obstructive bronchitis]
Pulmonary Disease, Chronic Obstructive
[Effects of secretary leukocyte protease inhibitor-transfected bone marrow mesenchymal stem cells on airway inflammation and mucus secretion in chronic obstructive pulmonary disease].
Pulmonary Disease, Chronic Obstructive
[Protease inhibitors from lung, secretions and blood in horses and cattle: a comparative study on endogenous, predisposing factors of chronic obstructive lung disease]
Pulmonary Disease, Chronic Obstructive
[Proteases and protease inhibitors of possible clinical relevance in COPD of horses]
Pulmonary Edema
Importance of serratia protease in the pathogenesis of experimental Serratia marcescens pneumonia.
Pulmonary Edema
Use of a protease inhibitor, ulinastatin, for reexpansion pulmonary edema following evacuation of bilateral pleural effusion.
Pulmonary Edema
Using a Caesalpinia echinata Lam. protease inhibitor as a tool for studying the roles of neutrophil elastase, cathepsin G and proteinase 3 in pulmonary edema.
Pulmonary Embolism
[Experimental pulmonary embolism in dogs. Local administration of Aspergillus-oryzae protease I]
Pulmonary Emphysema
A novel SERPINA1 mutation causing serum alpha(1)-antitrypsin deficiency.
Pulmonary Emphysema
A polymorphism of the alpha1-antitrypsin gene represents a risk factor for liver disease.
Pulmonary Emphysema
Correlation of lung surface area to apoptosis and proliferation in human emphysema.
Pulmonary Emphysema
Loss of skin elasticity is associated with pulmonary emphysema, biomarkers of inflammation, and matrix metalloproteinase activity in smokers.
Pulmonary Emphysema
Modulation of elastase binding to elastin by human alveolar macrophage-derived lipids.
Pulmonary Emphysema
Pallid mice with genetic emphysema. Neutrophil elastase burden and elastin loss occur without alteration in the bronchoalveolar lavage cell population.
Pulmonary Emphysema
Pharmacological and genetic reappraisals of protease and oxidative stress pathways in a mouse model of obstructive lung diseases.
Pulmonary Emphysema
Polymorphisms of ?1-antitrypsin and Interleukin-6 genes and the progression of hepatic cirrhosis in patients with a hepatitis C virus infection.
Pulmonary Emphysema
Protease inhibitor phenotypes and pulmonary disease in patients with Sjögren's syndrome.
Pulmonary Emphysema
Protection of rat lung from elastase-induced elastic fiber degradation in vitro and from emphysema in vivo by a trifluoroacetylpeptide anilide inhibitor.
Pulmonary Emphysema
Pulmonary deposition and disappearance of aerosolised secretory leucocyte protease inhibitor.
Pulmonary Emphysema
Relation of serum elastin peptide concentration to age, FEV1, smoking habits, alcohol consumption, and protease inhibitor phenotype: an epidemiological study in working men.
Pulmonary Emphysema
Role of secretory leukocyte protease inhibitor in the development of subclinical emphysema.
Pulmonary Emphysema
Serine Protease Imbalance in the Small Airways and Development of Centrilobular Emphysema in COPD.
Pulmonary Emphysema
Siiyama (serine 53 (TCC) to phenylalanine 53 (TTC)). A new alpha 1-antitrypsin-deficient variant with mutation on a predicted conserved residue of the serpin backbone.
Pulmonary Emphysema
Spontaneous hepatic repopulation in transgenic mice expressing mutant human ?1-antitrypsin by wild-type donor hepatocytes.
Pulmonary Emphysema
Structural modelling and thermostability of a serine protease inhibitor belonging to the Kunitz-BPTI family from the Rhipicephalus microplus tick.
Pulmonary Emphysema
Synthesis of stress proteins is increased in individuals with homozygous PiZZ alpha 1-antitrypsin deficiency and liver disease.
Pulmonary Emphysema
[Alpha 1-antitrypsin genes in patients with alpha 1AT deficiency in Japan: mutational analysis and allelic background]
Pulmonary Emphysema
[Combined primary pulmonary emphysema with multiple herniated intervertebral disks and protease inhibitor deficiency]
Pulmonary Emphysema
[Probucol inhibits tobacco smoke-induced decrease in plasma anti-elastase activity and ferroxidase activity in rats]
Pulmonary Emphysema
[Proteases and protease inhibitors of possible clinical relevance in COPD of horses]
Pulmonary Fibrosis
Diallylsulfide attenuates excessive collagen production and apoptosis in a rat model of bleomycin induced pulmonary fibrosis through the involvement of protease activated receptor-2.
Pulmonary Fibrosis
Essential role for the ATG4B protease and autophagy in bleomycin-induced pulmonary fibrosis.
Pulmonary Fibrosis
Functions of pulmonary epithelial integrins: from development to disease.
Pulmonary Fibrosis
Hematopoietic protease nexin-1 protects against lung injury by preventing thrombin signaling in mice.
Pulmonary Fibrosis
IL-32? attenuates airway fibrosis by modulating the integrin-FAK signaling pathway in fibroblasts.
Pulmonary Fibrosis
Inactivation of AP1 proteins by a nuclear serine protease precedes the onset of radiation-induced fibrosing alveolitis.
Pulmonary Fibrosis
Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 Inhibitor as a Novel Therapeutic Tool for Lung Injury.
Pulmonary Fibrosis
Secretory leukocyte protease inhibitor gene deletion alters bleomycin-induced lung injury, but not development of pulmonary fibrosis.
Pulmonary Fibrosis
Targeting protease activated receptor-1 with P1pal-12 limits bleomycin-induced pulmonary fibrosis.
Pulmonary Fibrosis
[Recent advances in the study of the mechanisms of silica-induced pulmonary fibrosis]
Purpura
A perspective on the measurement of ADAMTS13 in thrombotic thrombocytopaenic purpura.
Purpura
Are increased levels of von Willebrand factor in chronic coronary heart disease caused by decrease in von Willebrand factor cleaving protease activity? A study by an immunoassay with antibody against intact bond 842Tyr-843Met of the von Willebrand factor protein.
Purpura
Detection of autoantibodies against myeloid lysosomal enzymes: a useful adjunct to classification of patients with biopsy-proven necrotizing arteritis.
Purpura
Emerging roles of adjunct therapies in acquired thrombotic thrombocytopenia purpura.
Purpura
Refractory thrombotic thrombocytopenic purpura associated with oral contraceptives and factor V Leiden: a case report.
Purpura, Thrombocytopenic, Idiopathic
MALT1 protease activity is required for Fc?R-induced arthritis but not Fc?R-mediated platelet elimination in mice.
Purpura, Thrombotic Thrombocytopenic
A case of thrombotic thrombocytopenic purpura induced by acute pancreatitis.
Purpura, Thrombotic Thrombocytopenic
ADAMTS-13 plasma level determination uncovers antigen absence in acquired thrombotic thrombocytopenic purpura and ethnic differences.
Purpura, Thrombotic Thrombocytopenic
ADAMTS13 and anti-ADAMTS13 antibodies as markers for recurrence of acquired thrombotic thrombocytopenic purpura during remission.
Purpura, Thrombotic Thrombocytopenic
ADAMTS13 autoantibodies in patients with thrombotic microangiopathies and other immunomediated diseases.
Purpura, Thrombotic Thrombocytopenic
ADAMTS13 gene mutation in congenital thrombotic thrombocytopenic purpura with previously reported normal VWF cleaving protease activity.
Purpura, Thrombotic Thrombocytopenic
An update on the pathogenesis and management of acquired thrombotic thrombocytopenic purpura.
Purpura, Thrombotic Thrombocytopenic
Anti-Factor H autoantibodies associated with atypical hemolytic uremic syndrome.
Purpura, Thrombotic Thrombocytopenic
Antibodies to von Willebrand factor-cleaving protease in acute thrombotic thrombocytopenic purpura.
Purpura, Thrombotic Thrombocytopenic
Apheresis in cryoglobulinemia complicating hepatitis C and in other renal diseases.
Purpura, Thrombotic Thrombocytopenic
Assay of von Willebrand factor (vWF)-cleaving protease based on decreased collagen binding affinity of degraded vWF: a tool for the diagnosis of thrombotic thrombocytopenic purpura (TTP)
Purpura, Thrombotic Thrombocytopenic
Association between thrombotic microangiopathy and reduced ADAMTS13 activity in malignant hypertension.
Purpura, Thrombotic Thrombocytopenic
Carboxiterminal pro-endothelin-1 as an endothelial cell biomarker in thrombotic thrombocytopenic purpura.
Purpura, Thrombotic Thrombocytopenic
Cloning, expression and functional characterization of the full-length murine ADAMTS13.
Purpura, Thrombotic Thrombocytopenic
Comparison and stability of ADAMTS13 activity in therapeutic plasma products.
Purpura, Thrombotic Thrombocytopenic
Comparison of ADAMTS13 and Von Willebrand factor levels and activities, and plasminogen levels, in plasma products currently available for the treatment of thrombotic thrombocytopenic purpura in South Africa.
Purpura, Thrombotic Thrombocytopenic
Concentration and Subclass Distribution of Anti-ADAMTS13 IgG Autoantibodies in Different Stages of Acquired Idiopathic Thrombotic Thrombocytopenic Purpura.
Purpura, Thrombotic Thrombocytopenic
Congenital thrombotic thrombocytopenic purpura caused by new compound heterozygous mutations of the ADAMTS13 gene.
Purpura, Thrombotic Thrombocytopenic
Coombs Positive Thrombotic Thrombocytopenic Purpura in a Male Pediatric Patient: An Urgent Diagnostic Challenge.
Purpura, Thrombotic Thrombocytopenic
Correlation of thrombotic thrombocytopenic purpura disease activity with von Willibrand factor-cleaving protease level in ulcerative colitis.
Purpura, Thrombotic Thrombocytopenic
COVID-19 as a Potential Trigger for Immune Thrombotic Thrombocytopenic Purpura and Reason for an Unusual Treatment: A Case Report.
Purpura, Thrombotic Thrombocytopenic
Deficiency of ADAMTS13 in thrombotic thrombocytopenic purpura.
Purpura, Thrombotic Thrombocytopenic
Developments in the use of plasma exchange and adjunctive therapies to treat immune-mediated thrombotic thrombocytopenic purpura.
Purpura, Thrombotic Thrombocytopenic
Diagnosis and follow-up of thrombotic thrombocytopenic purpura with an automated chemiluminescent ADAMTS13 activity immunoassay.
Purpura, Thrombotic Thrombocytopenic
Effect of ADAMTS13 activity turnaround time on plasma utilization for suspected thrombotic thrombocytopenic purpura.
Purpura, Thrombotic Thrombocytopenic
Enzymatically active ADAMTS13 variants are not inhibited by anti-ADAMTS13 autoantibodies: a novel therapeutic strategy?
Purpura, Thrombotic Thrombocytopenic
Epitope mapping of ADAMTS13 autoantibodies in acquired thrombotic thrombocytopenic purpura.
Purpura, Thrombotic Thrombocytopenic
Estimation of the von Willebrand factor-cleaving protease in plasma using monoclonal antibodies to vWF.
Purpura, Thrombotic Thrombocytopenic
Evaluation of a rapid turn-over, fully-automated ADAMTS13 activity assay: a method comparison study.
Purpura, Thrombotic Thrombocytopenic
Expression and characterization of recombinant human ADAMTS-13.
Purpura, Thrombotic Thrombocytopenic
Immunotherapy for thrombotic thrombocytopenic purpura.
Purpura, Thrombotic Thrombocytopenic
In-vitro and in-vivo consequences of mutations in the von Willebrand factor cleaving protease ADAMTS13 in thrombotic thrombocytopenic purpura.
Purpura, Thrombotic Thrombocytopenic
Inhibitors of von Willebrand factor-cleaving protease in thrombotic thrombocytopenic purpura.
Purpura, Thrombotic Thrombocytopenic
Inhibitory autoantibodies against ADAMTS-13 in patients with thrombotic thrombocytopenic purpura bind ADAMTS-13 protease and may accelerate its clearance in vivo.
Purpura, Thrombotic Thrombocytopenic
Making the Correct Diagnosis in Thrombotic Microangiopathy: A Narrative Review.
Purpura, Thrombotic Thrombocytopenic
MASP2 levels are elevated in thrombotic microangiopathies: association with microvascular endothelial cell injury and suppression by anti-MASP2 antibody narsoplimab.
Purpura, Thrombotic Thrombocytopenic
Novel, semi-automated, 60-min-assay to determine von Willebrand factor cleaving activity of ADAMTS-13.
Purpura, Thrombotic Thrombocytopenic
Pathogenesis of Shiga toxin-induced hemolytic uremic syndrome.
Purpura, Thrombotic Thrombocytopenic
Patients with localized and disseminated tumors have reduced but measurable levels of ADAMTS-13 (von Willebrand factor cleaving protease).
Purpura, Thrombotic Thrombocytopenic
Postoperative thrombotic thrombocytopenic purpura in an infant: case report and literature review.
Purpura, Thrombotic Thrombocytopenic
Prolonged inhibition of von Willebrand factor-cleaving protease after splenectomy in a 22-year-old patient with acute and plasma refractory thrombotic thrombocytopenic purpura.
Purpura, Thrombotic Thrombocytopenic
Recombinant ADAMTS13 normalizes von Willebrand factor-cleaving activity in plasma of acquired TTP patients by overriding inhibitory antibodies.
Purpura, Thrombotic Thrombocytopenic
Rituximab and intermediate-purity plasma-derived factor VIII concentrate (Koate®) as adjuncts to therapeutic plasma exchange for thrombotic thrombocytopenic purpura in patients with an ADAMTS13 inhibitor.
Purpura, Thrombotic Thrombocytopenic
Rituximab for chronic recurring thrombotic thrombocytopenic purpura: a case report and review of the literature.
Purpura, Thrombotic Thrombocytopenic
Rituximab for refractory and or relapsing thrombotic thrombocytopenic purpura related to immune-mediated severe ADAMTS13-deficiency: a report of four cases and a systematic review of the literature.
Purpura, Thrombotic Thrombocytopenic
Rituximab in the treatment of relapsed thrombotic thrombocytopenic purpura.
Purpura, Thrombotic Thrombocytopenic
Severe malaria is associated with a deficiency of von Willebrand factor cleaving protease, ADAMTS13.
Purpura, Thrombotic Thrombocytopenic
Specific von Willebrand factor-cleaving protease in thrombotic microangiopathies: a study of 111 cases.
Purpura, Thrombotic Thrombocytopenic
Ten years of prophylactic treatment with fresh-frozen plasma in a child with chronic relapsing thrombotic thrombocytopenic purpura as a result of a congenital deficiency of von Willebrand factor-cleaving protease.
Purpura, Thrombotic Thrombocytopenic
The role of ADAMTS13 testing in the diagnosis and management of thrombotic microangiopathies and thrombosis.
Purpura, Thrombotic Thrombocytopenic
The role of human leukocyte antigen DRB1-DQB1 haplotypes in the susceptibility to acquired idiopathic thrombotic thrombocytopenic purpura.
Purpura, Thrombotic Thrombocytopenic
The use of 50% albumin/plasma replacement fluid in therapeutic plasma exchange for thrombotic thrombocytopenic purpura.
Purpura, Thrombotic Thrombocytopenic
Thrombocytopenia and severe hyperbilirubinemia in the neonatal period secondary to congenital thrombotic thrombocytopenic purpura and ADAMTS13 deficiency.
Purpura, Thrombotic Thrombocytopenic
Thrombotic thrombocytopenic purpura associated with Staphylococcus aureus endocarditis in a diabetic with furunculosis.
Purpura, Thrombotic Thrombocytopenic
Thrombotic Thrombocytopenic Purpura Masquerading as Acute Ischemic Stroke.
Purpura, Thrombotic Thrombocytopenic
Two approaches to the clinical dilemma of treating TTP with therapeutic plasma exchange in patients with a history of anaphylactic reactions to plasma.
Purpura, Thrombotic Thrombocytopenic
von Willebrand factor and its cleaving protease ADAMTS13 balance in coronary artery vessels: Lessons learned from thrombotic thrombocytopenic purpura. A narrative review.
Purpura, Thrombotic Thrombocytopenic
von Willebrand factor cleaving protease (ADAMTS-13) and ADAMTS-13 neutralizing autoantibodies in 100 patients with thrombotic thrombocytopenic purpura.
Purpura, Thrombotic Thrombocytopenic
Von Willebrand factor cleaving protease (ADAMTS-13) in 123 patients with connective tissue diseases (systemic lupus erythematosus and systemic sclerosis).
Purpura, Thrombotic Thrombocytopenic
Von Willebrand factor, ADAMTS13, and thrombotic thrombocytopenic purpura.
Purpura, Thrombotic Thrombocytopenic
von Willebrand factor, von Willebrand factor-cleaving protease, and shear stress.
Purpura, Thrombotic Thrombocytopenic
Von Willebrand factor--cleaving protease activity in congenital thrombotic thrombocytopenic purpura.
Purpura, Thrombotic Thrombocytopenic
von Willebrand factor-cleaving protease (ADAMTS-13) activity determination in the diagnosis of thrombotic microangiopathies: the Swiss experience.
Purpura, Thrombotic Thrombocytopenic
von Willebrand factor-cleaving protease in childhood diarrhoea-associated haemolytic uraemic syndrome.
Purpura, Thrombotic Thrombocytopenic
von Willebrand factor-cleaving protease in thrombotic thrombocytopenic purpura and the hemolytic-uremic syndrome.
Purpura, Thrombotic Thrombocytopenic
von Willebrand factor-cleaving protease inhibitor in a patient with human immunodeficiency syndrome-associated thrombotic thrombocytopenic purpura.
Purpura, Thrombotic Thrombocytopenic
VWF-cleaving protease (ADAMTS13) in premature infants.
Purpura, Thrombotic Thrombocytopenic
[Determination of the ADAMTS13 antigen and its activity in TTP patients and carriers]
Purpura, Thrombotic Thrombocytopenic
[Hereditary hemolytic uremic syndromes and thrombotic thrombocytopenic purpura]
Purpura, Thrombotic Thrombocytopenic
[Paediatric case report of an acquired autoimmune thrombotic thrombocytopenic purpura]
Purpura, Thrombotic Thrombocytopenic
[The role of von Willebrand protease in aetiopathogenesis of thrombotic thrombocytopenic purpura]
Purpura, Thrombotic Thrombocytopenic
[Thrombotic microangiopathy under an effective treatment with gemcitabine]
Purpura, Thrombotic Thrombocytopenic
[Thrombotic thrombocytopenic purpura. Reduced activity of von Willebrand factor cleaving protease]
Purpura, Thrombotic Thrombocytopenic
[Variety of thrombotic thrombocytopenic purpura clinical course in Polish family members with ADAMTS 13 gene mutation].
Purpura, Thrombotic Thrombocytopenic
[Von Willebrand factor and ADAMTS13 balancing primary haemostasis.]
Pycnodysostosis
Bilateral subtrochanteric femoral fracture due to a very rare disease: Pycnodisostosis.
Pyelonephritis
Alpha 1-antitrypsin and antithrombin III in atrophic nephrons of chronic pyelonephritis.
Pyelonephritis
Deposition of alpha 1-antitrypsin and loss of glycoconjugate carrying Ulex europaeus agglutinin-I binding sites in the glomerular sclerotic process. Phenomena common to chronic pyelonephritis and chronic diffuse proliferative glomerulonephritis.
Pyelonephritis
Pearls and pitfalls in the diagnosis of ureterolithiasis with unenhanced helical CT.
Pyoderma
A synthetic M protein peptide synergizes with a CXC chemokine protease to induce vaccine-mediated protection against virulent streptococcal pyoderma and bacteremia.
pyruvate dehydrogenase (nadp+) deficiency
Bi-allelic mutations of LONP1 encoding the mitochondrial LonP1 protease cause pyruvate dehydrogenase deficiency and profound neurodegeneration with progressive cerebellar atrophy.
Pyruvate Dehydrogenase Complex Deficiency Disease
Bi-allelic mutations of LONP1 encoding the mitochondrial LonP1 protease cause pyruvate dehydrogenase deficiency and profound neurodegeneration with progressive cerebellar atrophy.
Rabies
A novel oral rabies vaccine enhances the immunogenicity through increasing dendritic cells activation and germinal center formation by expressing U-OMP19 in a mouse model.
Rabies
Semliki Forest Virus replicon particles production in serum-free medium BHK-21 cell cultures and their use to express different proteins.
Rabies
Some effects of a bacterial protease on the complement fixing antigenicity of rabies virus.
Rectal Neoplasms
High SPINK4 Expression Predicts Poor Outcomes among Rectal Cancer Patients Receiving CCRT.
Relapsing Fever
Relapsing fever spirochaetes produce a serine protease that provides resistance to oxidative stress and killing by neutrophils.
Relapsing Fever
The bacterial nucleoid visualized by fluorescence microscopy of cells lysed within agarose: comparison of Escherichia coli and spirochetes of the genus Borrelia.
Renal Insufficiency
Acute renal failure in zebrafish: a novel system to study a complex disease.
Renal Insufficiency
Alteration in insulin-like growth factor-binding proteins (IGFBPs) and IGFBP-3 protease activity in serum and urine from acute and chronic renal failure.
Renal Insufficiency
Caspase inhibition causes hyperacute tumor necrosis factor-induced shock via oxidative stress and phospholipase A2.
Renal Insufficiency
Effects of calcitriol on the biogenesis of a lysosomal protease in monocytes from patients with renal failure.
Renal Insufficiency
Effects of protease therapy in the remnant kidney model of progressive renal failure.
Renal Insufficiency
Nephrolithiasis and renal failure among patients exposed to atazanavir, other PIs and PI-free regimens.
Renal Insufficiency
Prasugrel and Acquired Thrombotic Thrombocytopenic Purpura Associated with ADAMTS13 Activity Deficiency.
Renal Insufficiency
Protease inhibitors and haptoglobin for treatment of renal failure in paroxysmal nocturnal hemoglobinuria.
Renal Insufficiency
Renal events among women treated with tenofovir/emtricitabine in combination with either lopinavir/ritonavir or nevirapine: analysis from the AIDS Clinical Trial Group A5208 trial.
Renal Insufficiency
Renal function in experimentally induced acute pancreatitis in dogs: how it is affected by the nephrotoxic substance in pancreatic exudate from ascitic fluid.
Renal Insufficiency
The "cutting" edge: von Willebrand factor-cleaving protease activity in thrombotic microangiopathies.
Renal Insufficiency
The alpha1-antitrypsin/elastase complex as an experimental model for hemodialysis in acute catabolic renal failure, extracorporeal blood circulation and cardiocirculatory bypass.
Renal Insufficiency
The use of statins in conjunction with protease inhibitors and in renal insufficiency.
Renal Insufficiency
Treat chronic hepatitis C virus infection in decompensated cirrhosis - pre- or post-liver transplantation? the ironic conundrum in the era of effective and well-tolerated therapy.
Renal Insufficiency
von Willebrand factor-cleaving protease (ADAMTS-13) activity determination in the diagnosis of thrombotic microangiopathies: the Swiss experience.
Renal Insufficiency, Chronic
Combination therapy with renin-angiotensin-aldosterone system inhibitor telmisartan and serine protease inhibitor camostat mesilate provides further renoprotection in a rat chronic kidney disease model.
Renal Insufficiency, Chronic
CONSENSUS STATEMENT BY THE AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS AND AMERICAN COLLEGE OF ENDOCRINOLOGY ON THE COMPREHENSIVE TYPE 2 DIABETES MANAGEMENT ALGORITHM - 2019 EXECUTIVE SUMMARY.
Renal Insufficiency, Chronic
CONSENSUS STATEMENT BY THE AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS AND AMERICAN COLLEGE OF ENDOCRINOLOGY ON THE COMPREHENSIVE TYPE 2 DIABETES MANAGEMENT ALGORITHM - 2020 EXECUTIVE SUMMARY.
Renal Insufficiency, Chronic
Cumulative and current exposure to potentially nephrotoxic antiretrovirals and development of chronic kidney disease in HIV-positive individuals with a normal baseline estimated glomerular filtration rate: a prospective international cohort study.
Renal Insufficiency, Chronic
Evidence for the participation of proteases on protein catabolism during hypercatabolic renal failure.
Renal Insufficiency, Chronic
HIV protease inhibitor ritonavir induces renal fibrosis and dysfunction: role of platelet-derived TGF-?1 and intervention via anti-oxidant pathways.
Renal Insufficiency, Chronic
Incidence of Acute Kidney Injury in Patients Coinfected with HIV and Hepatitis C Virus Receiving Tenofovir Disoproxil Fumarate and Ledipasvir/Sofosbuvir in a Real-World, Urban, Ryan White Clinic.
Renal Insufficiency, Chronic
Inhibition of lysosomal protease cathepsin D reduces renal fibrosis in murine chronic kidney disease.
Renal Insufficiency, Chronic
New treatment for hepatitis C in chronic kidney disease, dialysis, and transplant.
Renal Insufficiency, Chronic
Overhydration Measured by Bioimpedance Spectroscopy and Urinary Serine Protease Activity Are Risk Factors for Progression of Chronic Kidney Disease.
Renal Insufficiency, Chronic
Real-world safety and efficacy of sofosbuvir and ledipasvir for elderly patients.
Renal Insufficiency, Chronic
Serum Cystatin C and Arterial Stiffness in Middle-Aged and Elderly Adults without Chronic Kidney Disease: A Population-Based Study.
Renal Insufficiency, Chronic
Serum protease activity in chronic kidney disease patients: The GANI_MED renal cohort.
Renal Insufficiency, Chronic
The Serine Protease Inhibitor Camostat Mesilate Attenuates the Progression of Chronic Kidney Disease through its Antioxidant Effects.
Renal Insufficiency, Chronic
Use of contemporary protease inhibitors and risk of incident chronic kidney disease in HIV-positive persons; the D:A:D Study.
Renal Insufficiency, Chronic
[Novel treatments for hepatitis C virus infection in chronic kidney disease].
Renal Insufficiency, Chronic
[Plasma serine protease inhibitors in dialyzed patients with chronic renal insufficiency]
Reoviridae Infections
Addition of exogenous protease facilitates reovirus infection in many restrictive cells.
Reoviridae Infections
Avian reovirus-triggered apoptosis enhances both virus spread and the processing of the viral nonstructural muNS protein.
Reperfusion Injury
Attenuation of hepatic ischemia and reperfusion injury by serine protease inhibitor, FUT-175, in dogs.
Reperfusion Injury
Cardioprotection by a novel recombinant serine protease inhibitor in myocardial ischemia and reperfusion injury.
Reperfusion Injury
Crosstalk between thrombosis and inflammation in lung reperfusion injury.
Reperfusion Injury
Effect of protease inhibitor on ischemia-reperfusion injury to rat liver.
Reperfusion Injury
Effects of anti-inflammatory cytokine agent (FR167653) and serine protease inhibitor on warm ischemia-reperfusion injury of the liver graft.
Reperfusion Injury
Effects of gabexate mesilate (FOY) on ischemia-reperfusion-induced acute lung injury in dogs.
Reperfusion Injury
Elimination of Kupffer cells and administration of protease inhibitor improve graft viability and prevent reperfusion injury in NHBD.
Reperfusion Injury
Evaluation of a protease inhibitor in the prevention of ischemia and reperfusion injury in hepatectomy under intermittent Pringle maneuver.
Reperfusion Injury
Inhibition of myocardial cathepsin-L release during reperfusion following myocardial infarction improves cardiac function and reduces infarct size.
Reperfusion Injury
Nafamostat mesilate, a serine protease inhibitor, suppresses lipopolysaccharide-induced nitric oxide synthesis and apoptosis in cultured human trophoblasts.
Reperfusion Injury
Neuroprotective effect of urinary trypsin inhibitor against focal cerebral ischemia-reperfusion injury in rats.
Reperfusion Injury
Participation of caspase-3-like protease in necrotic cell death of myocardium during ischemia-reperfusion injury in rat hearts.
Reperfusion Injury
Potent cardioprotection from ischemia-reperfusion injury by a two-domain fusion protein comprising annexin V and Kunitz protease inhibitor.
Reperfusion Injury
Preconditioning with gabexate is superior to inosine for ameliorating acute renal ischemia-reperfusion injury in rats.
Reperfusion Injury
Prevention of lung ischemia-reperfusion injury by short hairpin RNA-mediated caspase-3 gene silencing.
Reperfusion Injury
Prostacyclin analog-suppressed ischemia-reperfusion injury of the rat liver: evaluation by calpain mu activation.
Reperfusion Injury
Protection by Carolina rinse solution, acidotic pH, and glycine against lethal reperfusion injury to sinusoidal endothelial cells of rat livers stored for transplantation.
Reperfusion Injury
Protective effect of S-nitrosylated alpha(1)-protease inhibitor on hepatic ischemia-reperfusion injury.
Reperfusion Injury
Recombinant Kunitz protease inhibitor ameliorates reperfusion injury in rat lung transplantation.
Reperfusion Injury
Reduction of myocardial reperfusion injury by aprotinin after regional ischemia and cardioplegic arrest.
Reperfusion Injury
The effect of aprotinin on brain ischemic-reperfusion injury after hemorrhagic shock in rats: an experimental study.
Reperfusion Injury
The effect of aprotinin on ischemia-reperfusion injury in an in situ normothermic ischemic lung model.
Reperfusion Injury
The effect of intestinal ischemia and reperfusion injury on ICAM-1 expression, endothelial barrier function, neutrophil tissue influx, and protease inhibitor levels in rats.
Reperfusion Injury
The effect of protease inhibitor on reperfusion injury after unilateral pulmonary ischemia.
Reperfusion Injury
The novel synthetic serine protease inhibitor CU-2010 dose-dependently reduces postoperative blood loss and improves postischemic recovery after cardiac surgery in a canine model.
Reperfusion Injury
Thrombospondin is upregulated by protease activated receptor-1 in renal ischaemia reperfusion injury.
Reperfusion Injury
Ubiquitin-specific protease 22 enhances intestinal cell proliferation and tissue regeneration after intestinal ischemia reperfusion injury.
Reperfusion Injury
Urinary trypsin inhibitor reduces C-X-C chemokine production in rat liver ischemia/reperfusion.
Reperfusion Injury
[Protective effect of adenosine preconditioning against spinal cord ischemia-reperfusion injury in rats].
Reproductive Tract Infections
Levels of vaginal secretory leukocyte protease inhibitor are decreased in women with lower reproductive tract infections.
Reproductive Tract Infections
Protease production by microorganisms associated with reproductive tract infection.
Respiratory Distress Syndrome
?1-Antitrypsin: Key Player or Bystander in Acute Respiratory Distress Syndrome?
Respiratory Distress Syndrome
Alpha-1-antichymotrypsin is an effective inhibitor of pancreatitis-induced lung injury.
Respiratory Distress Syndrome
Alpha-2-macroglobulin levels in early respiratory distress syndrome.
Respiratory Distress Syndrome
Anti-inflammatory activity of neutrophil elastase inhibitors.
Respiratory Distress Syndrome
Characterisation of eppin function: expression and activity in the lung.
Respiratory Distress Syndrome
Critical role of non-muscle myosin light chain kinase in thrombin-induced endothelial cell inflammation and lung PMN infiltration.
Respiratory Distress Syndrome
Effects of serine protease inhibitors on accumulation of polymorphonuclear leukocytes in the lung induced by acute pancreatitis in rats.
Respiratory Distress Syndrome
Gabexate mesilate, a synthetic protease inhibitor, attenuates endotoxin-induced pulmonary vascular injury by inhibiting tumor necrosis factor production by monocytes.
Respiratory Distress Syndrome
Plasma neutrophil lipocalin, elastase-alpha1-antitrypsin complex and neutrophil protease 4 in preterm infants with respiratory distress syndrome.
Respiratory Distress Syndrome
Protease inhibitors in bronchoalveolar lavage fluid from neonates with special reference to secretory leukocyte protease inhibitor.
Respiratory Distress Syndrome
Tracheobronchial aspirate fluid neutrophil lipocalin, elastase- and neutrophil protease-4-alpha1-antitrypsin complexes, protease inhibitors and free proteolytic activity in respiratory distress syndrome.
Respiratory Distress Syndrome
[The protease inhibitor potential in newborns with respiratory distress syndrome]
Respiratory Hypersensitivity
A fungal protease allergen provokes airway hyper-responsiveness in asthma.
Respiratory Insufficiency
Acute respiratory failure associated with the human immunodeficiency virus (HIV) protease inhibitor indinavir in an HIV-infected patient.
Respiratory Insufficiency
Lack of whey acidic protein (WAP) four-disulfide core domain protease inhibitor 2 (WFDC2) causes neonatal death from respiratory failure in mice.
Respiratory Insufficiency
Role of salivary protease activity in adherence of gram-negative bacilli to mammalian buccal epithelial cells in vivo.
Respiratory Syncytial Virus Infections
Type-I interferons induce lung protease responses following respiratory syncytial virus infection via RIG-I-like receptors.
Respiratory Tract Infections
Enterovirus D68 Protease 2Apro Targets TRAF3 To Subvert Host Innate Immune Responses.
Respiratory Tract Infections
Exuberant fibroblast activity compromises lung function via ADAMTS4.
Respiratory Tract Infections
Genotypic and phenotypic analyses of a Pseudomonas aeruginosa chronic bronchiectasis isolate reveal differences from cystic fibrosis and laboratory strains.
Respiratory Tract Infections
Good and bad molecular fingerprints for human rhinovirus 3C protease inhibition: identification, validation, and application in designing of new inhibitors through Monte Carlo-based QSAR study.
Respiratory Tract Infections
Pseudomonas aeruginosa proteolytically alters the interleukin 22-dependent lung mucosal defense.
Respiratory Tract Infections
[Plasma levels of mannan-binding lectin-associated serine protease 2 in children with upper respiratory tract infection].
Respiratory Tract Infections
[The pathogenetic therapy of acute respiratory diseases by aprotinin inhalations]
Restless Legs Syndrome
Genetic factors influencing ferritin levels in 14,126 blood donors: results from the Danish Blood Donor Study.
Retinal Degeneration
A novel de novo CAPN5 mutation in a patient with inflammatory vitreoretinopathy, hearing loss, and developmental delay.
Retinal Degeneration
Functional validation of a human CAPN5 exome variant by lentiviral transduction into mouse retina.
Retinal Detachment
Effect of highly active antiretroviral therapy on the incidence of HIV-related cytomegalovirus retinitis and retinal detachment.
Retinal Diseases
Structural Insights into the Unique Activation Mechanisms of a Non-classical Calpain and Its Disease-Causing Variants.
Retinal Dystrophies
Identification and partial purification of a nucleotide-stimulated protease in rat retina.
Retinal Neovascularization
The Serine Protease HTRA-1 Is a Biomarker for ROP and Mediates Retinal Neovascularization.
Retinal Perforations
Differential expression of vitreous proteins in proliferative diabetic retinopathy.
Retinal Perforations
Incomplete release of vitreomacular attachments after intravitreal ocriplasmin.
Retinal Vasculitis
Alpha 1 antitrypsin serum levels and phenotypes in patients with retinal vasculitis.
Retinal Vein Occlusion
[Clinical use of oral protease preparation "Dasen" in the treatment of retinal vein thrombosis and hyaloid hemorrhage]
Retinitis
Cicatrization of cytomegalovirus retinitis following introduction of highly active anti-retroviral therapy: uveitis as a possible indicator of good ocular prognosis.
Retinitis
Cystoid macular edema in a patient with acquired immunodeficiency syndrome and past ocular history of cytomegalovirus retinitis after initiation of protease inhibitors.
Retinitis
Cytomegalovirus retinitis in advanced HIV-infected patients treated with protease inhibitors: incidence and outcome over 2 years.
Retinitis
Effects of protease inhibitors on the course of CMV retinitis in relation to CD4+ lymphocyte responses in HIV+ patients.
Retinitis
Immune recovery vitritis associated with inactive cytomegalovirus retinitis: a new syndrome.
Retinitis
Improved outcome of cytomegalovirus retinitis in AIDS patients after introduction of protease inhibitors.
Retinitis
Incidence and risk factors for developing cytomegalovirus retinitis in HIV-infected patients receiving protease inhibitor therapy. Spanish CMV-AIDS Study Group.
Retinitis
Lack of reactivation of cytomegalovirus (CMV) retinitis after stopping CMV maintenance therapy in AIDS patients with sustained elevations in CD4 T cells in response to highly active antiretroviral therapy.
Retinitis
Long-lasting remission of cytomegalovirus retinitis without maintenance therapy in human immunodeficiency virus-infected patients.
Retinitis
Nonprogressive CMV retinitis in AIDS patients with protease inhibitors therapy for AIDS.
Retinitis
[Clinical course of cytomegalovirus retinitis with the different antiretroviral therapies in our hospital]
Retinoblastoma
A retinoblastoma susceptibility gene product, RB, targeting protease is regulated through the cell cycle.
Retinoblastoma
A unique cathepsin-like protease isolated from CV-1 cells is involved in rapid degradation of retinoblastoma susceptibility gene product, RB, and transcription factor SP1.
Retinoblastoma
Cleavage of retinoblastoma protein during apoptosis: an interleukin 1 beta-converting enzyme-like protease as candidate.
Retinoblastoma
Human papillomavirus E7 requires the protease calpain to degrade the retinoblastoma protein.
Retinoblastoma
Isolation of genes differentially expressed at the downstream anastomosis of prosthetic arterial grafts with use of mRNA differential display.
Retinoblastoma
Met72Thr polymorphism of pigment epithelium-derived factor gene and susceptibility to age-related macular degeneration.
Retinoblastoma
Pigment epithelium-derived factor promotes the survival and differentiation of developing spinal motor neurons.
Retinoblastoma
Posttranslational regulation of the retinoblastoma gene family member p107 by calpain protease.
Retinoblastoma
Sequential two-step cleavage of the retinoblastoma protein by caspase-3/-7 during etoposide-induced apoptosis.
Retinoblastoma
Silencing of integrated human papillomavirus type 18 oncogene transcription in cells expressing SerpinB2.
Retinoblastoma
Specific cleavage of the retinoblastoma protein by an ICE-like protease in apoptosis.
Retroviridae Infections
Improved 3D-QSAR Prediction by Multiple Conformational Alignments and Molecular Docking Studies to Design and Discover HIV-I Protease Inhibitors.
Rhabdomyolysis
Rhabdomyolysis after cerivastatin-gemfibrozil therapy in an HIV-infected patient with protease inhibitor-related hyperlipidemia.
Rhabdomyolysis
Rhabdomyolysis: a case study exploring the possible side effect of lipid lowering medication by a HIV positive patient taking a protease inhibitor.
Rhabdomyolysis
Severe rhabdomyolysis due to rosuvastatin in a liver transplant subject with human immunodeficiency virus and immunosuppressive therapy-related dyslipidemia.
Rhabdomyosarcoma
Stimulation of cell surface plasminogen activation by heparin and related polyionic substances.
Rheumatic Diseases
The TLC-NOSF (Technology Lipido-Colloid Plus Nano-Oligo Saccharide Factor) protease inhibitor for the treatment of ulceration in rheumatic disease A case report.
Rhinitis
Allergic reactions, including asthma, to the pineapple protease bromelain following occupational exposure.
Rhinitis
Histochemical study of dipeptidylpeptidase IV in the nasal cavity organs of laboratory rodents and man.
Rhinitis
Potential roles in rhinitis for protease and other enzymatic activities of allergens.
Rhinitis, Allergic
Blocking of protease allergens with inhibitors reduces allergic responses in allergic rhinitis and other allergic diseases.
Rhinitis, Allergic
Human cystatin SN is an endogenous protease inhibitor that prevents allergic rhinitis.
Rhinitis, Allergic
Mite and cockroach allergens activate protease-activated receptor 2 and delay epidermal permeability barrier recovery.
Rhinitis, Allergic
Secretory leukocyte protease inhibitor in normal, allergic and virus induced nasal secretions.
Rhinitis, Allergic
The Serine Protease Inhibitor, 4-(2-aminoethyl) Benzene Sulfonyl Fluoride Hydrochloride, Reduces Allergic Inflammation in a House Dust Mite Allergic Rhinitis Mouse Model.
Rhinitis, Allergic, Seasonal
Identification of Proteases and Protease Inhibitors in Allergenic and Non-Allergenic Pollen.
Rhinitis, Allergic, Seasonal
Molecular Cloning and Immunochemical Characterization of a Novel Major Japanese Cedar Pollen Allergen Belonging to the Aspartic Protease Family.
Rhinitis, Allergic, Seasonal
Protease activity of allergenic pollen of cedar, cypress, juniper, birch and ragweed.
Rift Valley Fever
High content image-based screening of a protease inhibitor library reveals compounds broadly active against Rift Valley fever virus and other highly pathogenic RNA viruses.
Rosacea
Cathelicidin, kallikrein 5, and serine protease activity is inhibited during treatment of rosacea with azelaic acid 15% gel.
Rosacea
Improved clinical outcome and biomarkers in adults with papulopustular rosacea treated with doxycycline modified-release capsules in a randomized trial.
Rosacea
Increased serine protease activity and cathelicidin promotes skin inflammation in rosacea.
Rosacea
Microscale coiling in bis-imidazolium supramolecular hydrogel fibres induced by the release of a cationic serine protease inhibitor.
Rosacea
Multifunctional Serine Protease Inhibitor-Coated Water-Soluble Gold Nanoparticles as a Novel Targeted Approach for the Treatment of Inflammatory Skin Diseases.
Rosacea
Reduction in serine protease activity correlates with improved rosacea severity in a small, randomized pilot study of a topical serine protease inhibitor.
Rosacea
TLR2 expression is increased in rosacea and stimulates enhanced serine protease production by keratinocytes.
Rosacea
Topical Treatment of Rosacea with Ivermectin Inhibits Gene Expression of Cathelicidin Innate Immune Mediators, LL-37 and KLK5, in Reconstructed and Ex Vivo Skin Models.
Rotavirus Infections
Protease inhibitors prevent the development of human rotavirus-induced diarrhea in suckling mice.
Rubella
AR-12 Inhibits Multiple Chaperones Concomitant With Stimulating Autophagosome Formation Collectively Preventing Virus Replication.
Rubella
Calcium-dependent association of calmodulin with the rubella virus nonstructural protease domain.
Rubella
Characterization of the rubella virus nonstructural protease domain and its cleavage site.
Rubella
Characterization of the zinc binding activity of the rubella virus nonstructural protease.
Rubella
Elucidation of the full genetic information of Japanese rubella vaccines and the genetic changes associated with in vitro and in vivo vaccine virus phenotypes.
Rubella
Identification of a Ca2+-binding domain in the rubella virus nonstructural protease.
Rubella
Protease and helicase domains are related to the temperature sensitivity of wild-type rubella viruses.
Rubella
Rubella virus nonstructural protein protease domains involved in trans- and cis-cleavage activities.
Rubella
The rubella virus nonstructural protease recognizes itself via an internal sequence present upstream of the cleavage site for trans-activity.
Rubella
The rubella virus nonstructural protease requires divalent cations for activity and functions in trans.
Salmonella Infections
Oral immunization with ATP-dependent protease-deficient mutants protects mice against subsequent oral challenge with virulent Salmonella enterica serovar typhimurium.
Salmonella Infections
Persistent Salmonella enterica Serovar Typhimurium Infection Induces Protease Expression During Intestinal Fibrosis.
Sarcoidosis
Mycobacterial catalase-peroxidase is a tissue antigen and target of the adaptive immune response in systemic sarcoidosis.
Sarcoidosis, Pulmonary
Behaviour of angiotensin converting enzyme, hydroxyproline and some protease inhibitors in pulmonary sarcoidosis.
Sarcoidosis, Pulmonary
Phagocyte enzymes in bronchoalveolar lavage from patients with pulmonary sarcoidosis and collagen vascular disorders.
Sarcoma
Characterization of the protease of a fish retrovirus, walleye dermal sarcoma virus.
Sarcoma
Fibroblast activation protein increases metastatic potential of fibrosarcoma line HT1080 through upregulation of integrin-mediated signaling pathways.
Sarcoma
Field bean protease inhibitor preparations, unlike methotrexate, can completely suppress Yoshida sarcoma tumor in rats.
Sarcoma
Identification and molecular cloning of a novel mouse mucosal mast cell serine protease.
Sarcoma
Identification of a new viral protein containing CAp30 and NCp10 sequences in murine and feline leukemia retroviruses.
Sarcoma
Imaging Primary Mouse Sarcomas After Radiation Therapy Using Cathepsin-Activatable Fluorescent Imaging Agents.
Sarcoma
Insulin-like growth factor binding protein-3 concentrations and insulin-like growth factor binding protein-3 protease activity in sera of patients with malignant solid tumors or leukemia.
Sarcoma
Molecular cloning of the mouse mast cell protease-5 gene. A novel secretory granule protease expressed early in the differentiation of serosal mast cells.
Sarcoma
Selective toxicity of a bacterial protease preparation for the rat bearing ascites sarcoma.
Sarcoma
Targeted inhibition of cell-surface serine protease Hepsin blocks prostate cancer bone metastasis.
Sarcoma
Up-regulation of Rho/ROCK signaling in sarcoma cells drives invasion and increased generation of protrusive forces.
Sarcoma
Virologic and immunologic parameters that predict clinical response of AIDS-associated Kaposi's sarcoma to highly active antiretroviral therapy.
Sarcoma 180
Proteolytic activities of mouse sarcoma 180 cells that are inhibited by Bowman-Birk and Kunitz protease inhibitors.
Sarcoma, Avian
A range of catalytic efficiencies with avian retroviral protease subunits genetically linked to form single polypeptide chains.
Sarcoma, Avian
An anticatalytic monoclonal antibody to avian plasminogen activator: its effect on behavior of RSV-transformed chick fibroblasts.
Sarcoma, Avian
Analysis of substrate interactions of the Rous sarcoma virus wild type and mutant proteases and human immunodeficiency virus-1 protease using a set of systematically altered peptide substrates.
Sarcoma, Avian
Assembly and processing of avian retroviral gag polyproteins containing linked protease dimers.
Sarcoma, Avian
Association of a protease (plasminogen activator) with a specific membrane fraction isolated from transformed cells.
Sarcoma, Avian
Avian sarcoma leukemia virus protease linked to the adjacent Gag polyprotein is enzymatically active.
Sarcoma, Avian
Characterization of a small (25-kilodalton) derivative of the Rous sarcoma virus Gag protein competent for particle release.
Sarcoma, Avian
Cleavage of the X-Pro peptide bond by pepsin is specific for the trans isomer.
Sarcoma, Avian
Close structural resemblance between putative polymerase of a Drosophila transposable genetic element 17.6 and pol gene product of Moloney murine leukaemia virus.
Sarcoma, Avian
Crystal structure of a retroviral protease proves relationship to aspartic protease family.
Sarcoma, Avian
Human immunodeficiency virus type 1 Vif binds the viral protease by interaction with its N-terminal region.
Sarcoma, Avian
In vitro transformation with Rous sarcoma virus and the pp60src-associated protein kinase.
Sarcoma, Avian
Inhibition of protease activity in cultures of rous sarcoma virus-transformed cells: effect on the transformed phenotype.
Sarcoma, Avian
Invasion of Rous sarcoma virus-transformed retinal cells: role of cell motility.
Sarcoma, Avian
Mechanism of inhibition of the retroviral protease by a Rous sarcoma virus peptide substrate representing the cleavage site between the gag p2 and p10 proteins.
Sarcoma, Avian
Modeling of structure of human immunodeficiency virus-1 protease with substrate based on crystal structure of Rous sarcoma virus protease.
Sarcoma, Avian
Molecular mechanics calculations on Rous sarcoma virus protease with peptide substrates.
Sarcoma, Avian
Mutational analysis of the substrate binding pockets of the Rous sarcoma virus and human immunodeficiency virus-1 proteases.
Sarcoma, Avian
Neutral protease activity of Rous sarcoma (RSV) transformed chick embryo fibroblasts.
Sarcoma, Avian
Phorbol ester-induced morphological changes in transformed chick fibroblasts: evidence for direct catalytic involvement of plasminogen activator.
Sarcoma, Avian
Point mutation in avian sarcoma leukaemia virus protease which increases its activity but impairs infectious virus production.
Sarcoma, Avian
Processing of avian retroviral gag polyprotein precursors is blocked by a mutation at the NC-PR cleavage site.
Sarcoma, Avian
Programming the Rous sarcoma virus protease to cleave new substrate sequences.
Sarcoma, Avian
Proteases from human immunodeficiency virus and avian myeloblastosis virus show distinct specificities in hydrolysis of multidomain protein substrates.
Sarcoma, Avian
Role of the Rous sarcoma virus p10 domain in shape determination of gag virus-like particles assembled in vitro and within Escherichia coli.
Sarcoma, Avian
Site-directed mutagenesis of the P2 region of the Rous sarcoma virus gag gene: effects on Gag polyprotein processing.
Sarcoma, Avian
Synergistic effect of tumor virus transformation and tumor promoter treatment on the production of plasminogen activator by chick embryo fibroblasts.
Sarcoma, Avian
The gag and pol genes of bovine leukemia virus: nucleotide sequence and analysis.
Sarcoma, Ewing
Expression of cellular FLICE inhibitory protein, caspase-8, and protease inhibitor-9 in Ewing sarcoma and implications for susceptibility to cytotoxic pathways.
Sarcoma, Ewing
Ubiquitin-Specific Protease 6 Functions as a Tumor Suppressor in Ewing Sarcoma through Immune Activation.
Sarcoma, Ewing
USP6-induced neoplasms: the biologic spectrum of aneurysmal bone cyst and nodular fasciitis.
Sarcoma, Experimental
Laminin in the cutaneous basement membrane as a potential target in lewisite vesication.
Sarcoma, Kaposi
A comparison of regimens based on non-nucleoside reverse transcriptase inhibitors or protease inhibitors in preventing Kaposi's sarcoma.
Sarcoma, Kaposi
Clinical and biological impact of antiretroviral therapy with protease inhibitors on HIV-related Kaposi's sarcoma.
Sarcoma, Kaposi
Complete histological regression of Kaposi's sarcoma following treatment with protease inhibitors despite persistence of HHV-8 in lesions.
Sarcoma, Kaposi
Complete remission of AIDS-related Kaposi's sarcoma associated with undetectable human herpesvirus-8 sequences during anti-HIV protease therapy.
Sarcoma, Kaposi
Different impact of anti-retroviral regimen containing protease inhibitors on development of HIV-related Kaposi sarcoma.
Sarcoma, Kaposi
Differential effect of HIV-1 protease inhibitors on P-glycoprotein function in multidrug-resistant variants of the human CD4+ T lymphoblastoid CEM cell line.
Sarcoma, Kaposi
Effect of protease inhibitor-based highly active antiretroviral therapy on survival in HIV-associated advanced Kaposi's sarcoma patients treated with chemotherapy.
Sarcoma, Kaposi
Effects of indinavir in a preliminary phase I study on dogs with stage III slenic hemangiosarcoma.
Sarcoma, Kaposi
HHV8 and Kaposi's sarcoma: should we really give up protease inhibitors in all HIV-infected patients?
Sarcoma, Kaposi
Impact of Antiretroviral Therapy on the Risk of Recurrence in HIV-1 Infected Patients with Kaposi Sarcoma: A Multicenter Cohort Experience.
Sarcoma, Kaposi
Impact of Protease Inhibitors on HIV-Associated Kaposi Sarcoma Incidence: A Systematic Review.
Sarcoma, Kaposi
Interferon-alpha2b With Protease Inhibitor-Based Antiretroviral Therapy in Patients With AIDS-Associated Kaposi Sarcoma: An AIDS Malignancy Consortium Phase I Trial.
Sarcoma, Kaposi
Kaposi's-sarcoma-associated herpesvirus is detected in peripheral blood mononuclear cells of HIV-infected homosexuals more often than in heterosexuals.
Sarcoma, Kaposi
Monitoring of endogenous interferon-alpha and human herpesvirus 8 in HIV-infected patients with Kaposi's sarcoma.
Sarcoma, Kaposi
Mucosal Kaposi's sarcoma following protease inhibitor therapy in an HIV-infected patient.
Sarcoma, Kaposi
Pilot study evaluating the interaction between paclitaxel and protease inhibitors in patients with human immunodeficiency virus-associated Kaposi's sarcoma: an Eastern Cooperative Oncology Group (ECOG) and AIDS Malignancy Consortium (AMC) trial.
Sarcoma, Kaposi
Regression of AIDS-related Kaposi's sarcoma following antiretroviral therapy with protease inhibitors: biological correlates of clinical outcome.
Sarcoma, Kaposi
Relapse of Kaposi's Sarcoma and HHV-8 viremia in an HIV-infected patient switching from protease inhibitor to integrase inhibitor-based antiretroviral therapy.
Sarcoma, Kaposi
Relapse of Kaposi's sarcoma in HIV-infected patients switching from a protease inhibitor to a non-nucleoside reverse transcriptase inhibitor-based highly active antiretroviral therapy regimen.
Sarcoma, Kaposi
Remission from Kaposi's sarcoma on HAART is associated with suppression of HIV replication and is independent of protease inhibitor therapy.
Sarcoma, Kaposi
Resolution of Kaposi's sarcoma associated with undetectable level of human herpesvirus 8 DNA in a patient with AIDS after protease inhibitor therapy.
Sarcoma, Kaposi
The pharmacokinetics of liposomal encapsulated daunorubicin are not modified by HAART in patients with HIV-associated Kaposi's sarcoma.
Sarcoma, Kaposi
Use of Boosted Protease Inhibitors Reduces Kaposi Sarcoma Incidence Among Male Veterans With HIV Infection.
Sarcoma, Kaposi
Use of HIV protease inhibitors to block Kaposi's sarcoma and tumour growth.
Sarcoma, Kaposi
[Pulmonary thromboembolism in HIV infected admitted patients under 50 years old.]
Sarcoma, Yoshida
Field bean protease inhibitor preparations, unlike methotrexate, can completely suppress Yoshida sarcoma tumor in rats.
Sarcopenia
Cross-sectional associations among P3NP, HtrA, Hsp70, Apelin and sarcopenia in Taiwanese population.
Sarcopenia
Loss of high-temperature requirement protein A2 protease activity induces mitonuclear imbalance via differential regulation of mitochondrial biogenesis in sarcopenia.
Sarcopenia
Sarcopenia in Persons Living with HIV under Antiretroviral Therapy: Literature Review.
Scabies
Characterisation of a serine protease homologous to house dust mite group 3 allergens from the scabies mite sarcoptes scabiei.
Scabies
Novel scabies mite serpins inhibit the three pathways of the human complement system.
Scabies
Scabies mite inactivated serine protease paralogs inhibit the human complement system.
Scabies
Scabies mite inactivated serine protease paralogues are present both internally in the mite gut and externally in feces.
Scabies
Scabies mite inactive serine proteases are potent inhibitors of the human complement lectin pathway.
Scarlet Fever
Outbreak of scarlet fever at a hospital day care centre: analysis of strain relatedness with phenotypic and genotypic characteristics.
Schistosomiasis
Activation route of the Schistosoma mansoni cathepsin B1 drug target: structural map with a glycosaminoglycan switch.
Schistosomiasis
Characterization of Ca(2+)-dependent neutral protease (calpain) from human blood flukes, Schistosoma mansoni.
Schistosomiasis
Establishment of Schistosoma japonicum calpain-specific mouse T cell hybridomas and identification of a T cell epitope that stimulates IFNgamma production.
Schistosomiasis
Peptides Derived of Kunitz-Type Serine Protease Inhibitor as Potential Vaccine Against Experimental Schistosomiasis.
Schistosomiasis
Role of T lymphocytes and papain enzymatic activity in the protection induced by the cysteine protease against Schistosoma mansoni in mice.
Schistosomiasis
SmSP2: A serine protease secreted by the blood fluke pathogen Schistosoma mansoni with anti-hemostatic properties.
Schistosomiasis
Species-Specific Serological Detection for Schistosomiasis by Serine Protease Inhibitor (SERPIN) in Multiplex Assay.
Schistosomiasis mansoni
Immunochemical characterization and purification of Sm-97, a Schistosoma mansoni antigen monospecifically recognized by antibodies from mice protectively immunized with a nonliving vaccine.
Schistosomiasis mansoni
Kunitz-type protease inhibitor as a vaccine candidate against schistosomiasis mansoni.
Scleroderma, Systemic
Autoantibody against a protease domain of caspase-8 in patients with systemic sclerosis.
Scleroderma, Systemic
Circulating fibroblast activation protein and dipeptidyl peptidase 4 in rheumatoid arthritis and systemic sclerosis.
Scleroderma, Systemic
Clinical significance of serum levels of secretory leukocyte protease inhibitor in patients with systemic sclerosis.
Scleroderma, Systemic
Protease nexin-1 messenger RNA levels are not affected by serum or interferon beta in cultured systemic sclerosis fibroblasts.
Scleroderma, Systemic
Von Willebrand factor cleaving protease (ADAMTS-13) in 123 patients with connective tissue diseases (systemic lupus erythematosus and systemic sclerosis).
Scoliosis
LONP1 is associated with the incidence of idiopathic scoliosis possibly via defective mitochondrial function.
Scrapie
Attempts to convert the cellular prion protein into the scrapie isoform in cell-free systems.
Scrapie
Biochemical properties of protease resistant prion protein PrPsc in natural sheep scrapie.
Scrapie
Characterization of a proteolytic enzyme derived from a Bacillus strain that effectively degrades prion protein.
Scrapie
Co-existence of scrapie prion protein types 1 and 2 in sporadic Creutzfeldt-Jakob disease: its effect on the phenotype and prion-type characteristics.
Scrapie
Comparative molecular analysis of the abnormal prion protein in field scrapie cases and experimental bovine spongiform encephalopathy in sheep by use of Western blotting and immunohistochemical methods.
Scrapie
Comparative study of the effects of several chemical and physical treatments on the activity of protease resistance and infectivity of scrapie strain 263K.
Scrapie
Comparison of detergent and protease enzyme combinations for the detection of scrapie-associated fibrils from the central nervous system of sheep naturally affected with scrapie.
Scrapie
Evidence suggesting that PrP is not the infectious agent in Creutzfeldt-Jakob disease.
Scrapie
Exposure of RML scrapie agent to a sodium percarbonate-based product and sodium dodecyl sulfate renders PrPSc protease sensitive but does not eliminate infectivity.
Scrapie
High-level expression and characterization of a purified 142-residue polypeptide of the prion protein.
Scrapie
Histopathological changes in the islets of Langerhans in scrapie 139H-affected hamsters.
Scrapie
Influence of Surface Functionality of Poly(propylene imine) Dendrimers on Protease Resistance and Propagation of the Scrapie Prion Protein.
Scrapie
Mapping the antigenicity of copper-treated cellular prion protein with the scrapie isoform.
Scrapie
Monitoring immune cells trafficking fluorescent prion rods hours after intraperitoneal infection.
Scrapie
Prion metal interaction: is prion pathogenesis a cause or a consequence of metal imbalance?
Scrapie
Prion protein gene variability in Spanish goats. Inference through susceptibility to classical scrapie strains and pathogenic distribution of peripheral PrP(sc.).
Scrapie
Prion seeding activities of mouse scrapie strains with divergent PrPSc protease sensitivities and amyloid plaque content using RT-QuIC and eQuIC.
Scrapie
Pronase does not reduce the protein content of Hirt supernatant of normal mouse brain.
Scrapie
Properties of the scrapie prion protein: quantitative analysis of protease resistance.
Scrapie
Protease sensitivity and nuclease resistance of the scrapie agent propagated in vitro in neuroblastoma cells.
Scrapie
Protease-resistant prion protein in brain and lymphoid organs of sheep within a naturally scrapie-infected flock.
Scrapie
PrP(c) mRNA, but not PrP(Sc) is found in the salivary glands of scrapie-infected sheep.
Scrapie
Scrapie infectivity correlates with converting activity, protease resistance, and aggregation of scrapie-associated prion protein in guanidine denaturation studies.
Scrapie
Scrapie protein degradation by cysteine proteases in CD11c+ dendritic cells and GT1-1 neuronal cells.
Scrapie
Screening of intact yeasts and cell extracts to reduce Scrapie prions during biotransformation of food waste.
Scrapie
Ultrastructural immuno-localization of synthetic prion protein peptide antibodies in 87V murine scrapie.
Seizures
A novel approach for imaging brain-behavior relationships in mice reveals unexpected metabolic patterns during seizures in the absence of tissue plasminogen activator.
Seizures
Amyloid precursor protein mRNA encoding the Kunitz protease inhibitor domain is increased by kainic acid-induced seizures in rat hippocampus.
Seizures
Detection of Protein Uptake in In Vitro Cultured Astrocytes Exemplified by the Uptake of the Serine Protease, Tissue Plasminogen Activator.
Seizures
Detection of truncated isoforms of human neuroserpin lacking the reactive center loop: Implications in noninhibitory role.
Seizures
Endogenous methionine enkephalin may play an anticonvulsant role in the seizure-susceptible El mouse.
Seizures
Ethanol-withdrawal seizures are controlled by tissue plasminogen activator via modulation of NR2B-containing NMDA receptors.
Seizures
Increased expression of matrix metalloproteinase 9 in cortical lesions from patients with focal cortical dysplasia type IIb and tuberous sclerosis complex.
Seizures
Increased expression of the lysosomal protease cathepsin S in hippocampal microglia following kainate-induced seizures.
Seizures
Involvement of caspase-3-like protease in the mechanism of cell death following focally evoked limbic seizures.
Seizures
LONP1 de novo dominant mutation causes mitochondrial encephalopathy with loss of LONP1 chaperone activity and excessive LONP1 proteolytic activity.
Seizures
Loss of hippocampal serine protease BSP1/neuropsin predisposes to global seizure activity.
Seizures
mRNAs encoding urokinase-type plasminogen activator and plasminogen activator inhibitor-1 are elevated in the mouse brain following kainate-mediated excitation.
Seizures
Neuroserpin Differentiates Between Forms of Tissue Type Plasminogen Activator via pH Dependent Deacylation.
Seizures
Regional distribution and time-course of calpain activation following kainate-induced seizure activity in adult rat brain.
Seizures
Seizure protein 6 controls glycosylation and trafficking of kainate receptor subunits GluK2 and GluK3.
Seizures
Seizures in patients with chronic hepatitis C treated with NS3/4A protease inhibitors: does pharmacological interaction play a role?
Seizures
The SUMO-specific protease SENP2 plays an essential role in the regulation of Kv7.2 and Kv7.3 potassium channels.
Seizures
Tissue-plasminogen activator is induced as an immediate-early gene during seizure, kindling and long-term potentiation.
Seizures
Viral-mediated delivery of the late-infantile neuronal ceroid lipofuscinosis gene, TPP-I to the mouse central nervous system.
Sepsis
Activated protein C mediates novel lung endothelial barrier enhancement: role of sphingosine 1-phosphate receptor transactivation.
Sepsis
Activated protein C protects vascular endothelial cells from apoptosis in malaria and in sepsis.
Sepsis
Activated protein C signals through the thrombin receptor PAR1 in endothelial cells.
Sepsis
Activation of Bacteroides fragilis toxin by a novel bacterial protease contributes to anaerobic sepsis in mice.
Sepsis
Acute stress response in children with meningococcal sepsis: important differences in the growth hormone/insulin-like growth factor I axis between nonsurvivors and survivors.
Sepsis
ADAMTS13 activity is decreased in a septic porcine model. Significance for glomerular thrombus deposition.
Sepsis
Aeromonas sobria serine protease (ASP): a subtilisin family endopeptidase with multiple virulence activities.
Sepsis
An exciting candidate therapy for sepsis: ulinastatin, a urinary protease inhibitor.
Sepsis
Calcium-dependent and calcium-independent protease activities in skeletal muscle during sepsis.
Sepsis
Changes in components of the plasma protease systems related to course and outcome of surgical sepsis.
Sepsis
Combined host and specific anti-Pseudomonas-directed therapy for Pseudomonas aeruginosa infections in burned mice: experimental results and theoretic considerations.
Sepsis
Demonstration of granulocytic proteases in plasma of patients with acute leukemia and septicemia with coagulation defects.
Sepsis
Diabetes-independent increase of factor VII-activating protease activation in patients with Gram-negative sepsis (melioidosis).
Sepsis
Effects of exogenous recombinant APC in mouse models of ischemia reperfusion injury and of atherosclerosis.
Sepsis
Effects of indomethacin and leupeptin on muscle cathepsin B activity and protein degradation during sepsis.
Sepsis
Elucidating sources and roles of granzymes A and B during bacterial infection and sepsis.
Sepsis
Endogenous EPCR/aPC-PAR1 signaling prevents inflammation-induced vascular leakage and lethality.
Sepsis
Engineering the proteolytic specificity of activated protein C improves its pharmacological properties.
Sepsis
Enhanced release of elastase is not concomitant with increased secretion of granulocyte-activating cytokines in whole blood from patients with sepsis.
Sepsis
Evaluation of severity and prognosis in early stages of septicemia by means of chromogenic peptide substrate assays.
Sepsis
Evidence that cathepsin B contributes to skeletal muscle protein breakdown during sepsis.
Sepsis
Gabexate mesilate, a synthetic anticoagulant, inhibits the expression of endothelial leukocyte adhesion molecules in vitro.
Sepsis
Granzyme A inhibition reduces inflammation and increases survival during abdominal sepsis.
Sepsis
Hemodynamic, renal, and hormonal actions of aprotinin in an ovine model of septic shock.
Sepsis
Heparin-binding protein as a novel biomarker for sepsis-related acute kidney injury.
Sepsis
IL-15 constrains mast cell-dependent antibacterial defenses by suppressing chymase activities.
Sepsis
IL-1beta induction of NF-kappaB activation in human intestinal epithelial cells is independent of oxyradical signaling.
Sepsis
Improved survival in experimental sepsis with an orally administered inhibitor of apoptosis.
Sepsis
Influence of plasma protease activation on electroimmunoassay and nephelometry of plasma fibronectin in sepsis.
Sepsis
Inhibition of Neutrophil Migration by Hemopexin Leads to Increased Mortality Due to Sepsis in Mice.
Sepsis
Inter-alpha inhibitor protein administration improves survival from neonatal sepsis in mice.
Sepsis
Inter-alpha-trypsin inhibitor attenuates complement activation and complement-induced lung injury.
Sepsis
Intraintestinal administration of ulinastatin protects against sepsis by relieving intestinal damage.
Sepsis
Intravenous administration of ulinastatin (human urinary trypsin inhibitor) in severe sepsis: a multicenter randomized controlled study.
Sepsis
Limiting protease production plays a key role in the pathogenesis of the divergent clinical isolates of Staphylococcus aureus LAC and UAMS-1.
Sepsis
Myxomavirus-derived serpin prolongs survival and reduces inflammation and hemorrhage in an unrelated lethal mouse viral infection.
Sepsis
Nafamostat Attenuated the Impairment of Fibrinolysis in Animal Sepsis Model by Suppressing the Increase of Plasminogen Activator Inhibitor Type 1.
Sepsis
No Association of SERPINE1 -675 Polymorphism With Sepsis Susceptibility: A Meta-Analysis.
Sepsis
Pancreatic injuries in rats with fecal peritonitis: protective effect of a new synthetic protease inhibitor, sepinostat mesilate (FUT-187).
Sepsis
Plasma concentrations of secretory leukocyte protease inhibitor (SLPI) differ depending on etiology and severity in community-onset bloodstream infection.
Sepsis
Preserved Expression of mRNA Coding von Willebrand Factor-Cleaving Protease ADAMTS13 by Selenite and Activated Protein C.
Sepsis
Protease and phospholipase inhibition protect Veneza zonata (Hemiptera Coreidae) against septicemia caused by parasite trypanosomatid 563DT.
Sepsis
Protection of vascular barrier integrity by activated protein C in murine models depends on protease-activated receptor-1.
Sepsis
Protective cross talk between activated protein C and TNF signaling in vascular endothelial cells: implication of EPCR, noncanonical NF-{kappa}B, and ERK1/2 MAP kinases.
Sepsis
Quantification of Immune Dysregulation by Next-generation Polymerase Chain Reaction to Improve Sepsis Diagnosis in Surgical Patients.
Sepsis
Regulation of RelA/p65 and Endothelial Cell Inflammation by Proline-Rich Tyrosine Kinase 2.
Sepsis
Review of cellular and molecular pathways linking thrombosis and innate immune system during sepsis.
Sepsis
Role of bradykinin in microbial infection: enhancement of septicemia by microbial proteases and kinin.
Sepsis
Secretory leukocyte protease inhibitor, an inhibitor of neutrophil activation, is elevated in serum in human sepsis and experimental endotoxemia.
Sepsis
Selective attenuation of the extrinsic limb of the tissue factor-driven coagulation protease cascade by occupancy of a novel peptidyl docking site on tissue factor.
Sepsis
Shedding of the tumor necrosis factor (TNF) receptor from the surface of hepatocytes during sepsis limits inflammation through cGMP signaling.
Sepsis
Studies on components of the plasma kallikrein-kinin system in plasma samples from normal individuals and patients with septic shock.
Sepsis
The Effect of the Environmental Temperature on the Adaptation to Host in the Zoonotic Pathogen Vibrio vulnificus.
Sepsis
The high prevalence of serine protease autotransporters of Enterobacteriaceae (SPATEs) in Escherichia coli causing neonatal septicemia.
Sepsis
The Proteolytic Inactivation of Protein Z-Dependent Protease Inhibitor by Neutrophil Elastase Might Promote the Procoagulant Activity of Neutrophil Extracellular Traps in Sepsis.
Sepsis
The ScpC protease of Streptococcus pyogenes affects the outcome of sepsis in a murine model.
Sepsis
Treatment of porcine sepsis with high-dose antithrombin III reduces tissue edema and effusion but does not increase risk for bleeding.
Sepsis
Treatment of sepsis in the surgical patient evaluated by means of chromogenic peptide substrate assays.
Sepsis
Ulinastatin alone does not reduce caspase 3-mediated apoptosis in protease-positive Aeromonas hydrophilia-induced sepsis.
Sepsis
Ulinastatin ameliorates acute kidney injury induced by crush syndrome inflammation by modulating Th17/Treg cells.
Sepsis
Ulinastatin attenuates liver injury and inflammation in a cecal ligation and puncture induced sepsis mouse model.
Sepsis
Ulinastatin attenuates LPS-induced inflammation in mouse macrophage RAW264.7 cells by inhibiting the JNK/NF-?B signaling pathway and activating the PI3K/Akt/Nrf2 pathway.
Sepsis
Ulinastatin is a novel candidate drug for sepsis and secondary acute lung injury, evidence from an optimized CLP rat model.
Sepsis
Ulinastatin mediates suppression of regulatory T cells through TLR4/NF-?B signaling pathway in murine sepsis.
Sepsis
Ulinastatin Protects Against LPS-Induced Acute Lung Injury by Attenuating TLR4/NF-?B Pathway Activation and Reducing Inflammatory Mediators.
Sepsis
Ulinastatin Reduces the Severity of Intestinal Damage in the Neonatal Rat Model of Necrotizing Enterocolitis.
Sepsis
Vaccine based on a ubiquitous cysteinyl protease and streptococcal pyrogenic exotoxin A protects against Streptococcus pyogenes sepsis and toxic shock.
Sepsis
Variations in the ratio between von Willebrand factor and its cleaving protease during systemic inflammation and association with severity and prognosis of organ failure.
Sepsis
von Willebrand factor is a major determinant of ADAMTS-13 decrease during mouse sepsis induced by cecum ligation and puncture.
Sepsis
[Effect of reinfusion of UV-irradiated blood on the activity of the kallikrein-kinin system in patients with diffuse phlegmons of the face and neck]
Sepsis
[Peptide-agonist of protease-activated receptor (PAR 1), similar to activated protein C, promotesproliferation in keratinocytes and wound healing of epithelial layer.]
Sepsis
[Reduction in leukocyte elastase levels in patients with sepsis by administration of urinastatin]
Serum Sickness
Removal of glomerular immune complexes in passive serum sickness nephritis by treatment in vivo with proteolytic enzymes.
Severe Acute Respiratory Syndrome
A chimeric virus-mouse model system for evaluating the function and inhibition of papain-like proteases of emerging coronaviruses.
Severe Acute Respiratory Syndrome
A novel class of TMPRSS2 inhibitors potently block SARS-CoV-2 and MERS-CoV viral entry and protect human epithelial lung cells.
Severe Acute Respiratory Syndrome
A Review on Expression, Pathological Roles, and Inhibition of TMPRSS2, the Serine Protease Responsible for SARS-CoV-2 Spike Protein Activation.
Severe Acute Respiratory Syndrome
A transmembrane serine protease is linked to the severe acute respiratory syndrome coronavirus receptor and activates virus entry.
Severe Acute Respiratory Syndrome
ACE inhibition and cardiometabolic risk factors, lung ACE2 and TMPRSS2 gene expression, and plasma ACE2 levels: a Mendelian randomization study.
Severe Acute Respiratory Syndrome
ACE2 and TMPRSS2 expression by clinical, HLA, immune, and microbial correlates across 34 human cancers and matched normal tissues: implications for SARS-CoV-2 COVID-19.
Severe Acute Respiratory Syndrome
Activation of the SARS coronavirus spike protein via sequential proteolytic cleavage at two distinct sites.
Severe Acute Respiratory Syndrome
Alpha-1 Antitrypsin for COVID-19 Treatment: Dual Role in Antiviral Infection and Anti-Inflammation.
Severe Acute Respiratory Syndrome
An insightful recollection since the distorted key theory was born about 23?years ago.
Severe Acute Respiratory Syndrome
Angiotensin Converting Enzyme-2 (ACE-2) role in disease and future in research.
Severe Acute Respiratory Syndrome
Autoprocessing mechanism of severe acute respiratory syndrome coronavirus 3C-like protease (SARS-CoV 3CL(pro) ) from its polyproteins.
Severe Acute Respiratory Syndrome
Binding site-based classification of coronaviral papain-like proteases.
Severe Acute Respiratory Syndrome
Bioactive Indolyl Diketopiperazines from the Marine Derived Endophytic Aspergillusversicolor DY180635.
Severe Acute Respiratory Syndrome
Camostat Mesylate May Reduce Severity of Coronavirus Disease 2019 Sepsis: A First Observation.
Severe Acute Respiratory Syndrome
Cardiorenal Tissues Express SARS-CoV-2 Entry Genes and Basigin (BSG/CD147) Increases With Age in Endothelial Cells.
Severe Acute Respiratory Syndrome
Cigarette Smoke Stimulates SARS-CoV-2 Internalization by Activating AhR and Increasing ACE2 Expression in Human Gingival Epithelial Cells.
Severe Acute Respiratory Syndrome
Cleavage of the SARS coronavirus spike glycoprotein by airway proteases enhances virus entry into human bronchial epithelial cells in vitro.
Severe Acute Respiratory Syndrome
Co?expression of peripheral olfactory receptors with SARS?CoV?2 infection mediators: Potential implications beyond loss of smell as a COVID?19 symptom.
Severe Acute Respiratory Syndrome
Combining fragment docking with graph theory to improve ligand docking for homology model structures.
Severe Acute Respiratory Syndrome
Coronaviruses resistant to a 3C-like protease inhibitor are attenuated for replication and pathogenesis, revealing a low genetic barrier but high fitness cost of resistance.
Severe Acute Respiratory Syndrome
Design, synthesis, and molecular dynamics simulation studies of quinoline derivatives as protease inhibitors against SARS-CoV-2.
Severe Acute Respiratory Syndrome
Dissection study on the severe acute respiratory syndrome 3C-like protease reveals the critical role of the extra domain in dimerization of the enzyme: defining the extra domain as a new target for design of highly specific protease inhibitors.
Severe Acute Respiratory Syndrome
Early combination treatment with existing HIV antivirals: an effective treatment for COVID-19?
Severe Acute Respiratory Syndrome
Efficacy of the TMPRSS2 inhibitor camostat mesilate in patients hospitalized with Covid-19-a double-blind randomized controlled trial.
Severe Acute Respiratory Syndrome
Evaluation of peptide-aldehyde inhibitors using R188I mutant of SARS 3CL protease as a proteolysis-resistant mutant.
Severe Acute Respiratory Syndrome
Exposure to particulate matter upregulates ACE2 and TMPRSS2 expression in the murine lung.
Severe Acute Respiratory Syndrome
Genetic variations in the human severe acute respiratory syndrome coronavirus receptor ACE2 and serine protease TMPRSS2.
Severe Acute Respiratory Syndrome
Human eggs, zygotes, and embryos express the receptor angiotensin 1-converting enzyme 2 and transmembrane serine protease 2 protein necessary for severe acute respiratory syndrome coronavirus 2 infection.
Severe Acute Respiratory Syndrome
In search of drugs to alleviate suppression of the host's innate immune responses against SARS-CoV-2 using a molecular modeling approach.
Severe Acute Respiratory Syndrome
In silico prediction of SARS protease inhibitors by virtual high throughput screening.
Severe Acute Respiratory Syndrome
Lung and Kidney ACE2 and TMPRSS2 in Renin-Angiotensin System Blocker-Treated Comorbid Diabetic Mice Mimicking Host Factors That Have Been Linked to Severe COVID-19.
Severe Acute Respiratory Syndrome
New Chalcone Derivatives as Effective Anti-SARS-CoV-2 Agents.
Severe Acute Respiratory Syndrome
Novel influenza virus NS1 antagonists block replication and restore innate immune function.
Severe Acute Respiratory Syndrome
Positional-scanning fluorigenic substrate libraries reveal unexpected specificity determinants of DUBs (deubiquitinating enzymes).
Severe Acute Respiratory Syndrome
Potential of Flavonoid-Inspired Phytomedicines against COVID-19.
Severe Acute Respiratory Syndrome
Protease Inhibitors: Candidate Drugs to Inhibit Severe Acute Respiratory Syndrome Coronavirus 2 Replication.
Severe Acute Respiratory Syndrome
Re(I) Tricarbonyl Complexes as Coordinate Covalent Inhibitors for the SARS-CoV-2 Main Cysteine Protease.
Severe Acute Respiratory Syndrome
Residues on the Dimer Interface of SARS Coronavirus 3C-like Protease: Dimer Stability Characterization and Enzyme Catalytic Activity Analysis.
Severe Acute Respiratory Syndrome
Safety of protease inhibitors and Arbidol for SARS-CoV-2 pneumonia in Zhejiang Province, China.
Severe Acute Respiratory Syndrome
Screening strategy of TMPRSS2 inhibitors by FRET-based enzymatic activity for TMPRSS2-based cancer and COVID-19 treatment.
Severe Acute Respiratory Syndrome
Severe acute respiratory syndrome coronavirus papain-like novel protease inhibitors: design, synthesis, protein-ligand X-ray structure and biological evaluation.
Severe Acute Respiratory Syndrome
Structural Variability, Expression Profile, and Pharmacogenetic Properties of TMPRSS2 Gene as a Potential Target for COVID-19 Therapy.
Severe Acute Respiratory Syndrome
Structure-based design, synthesis, and evaluation of peptide-mimetic SARS 3CL protease inhibitors.
Severe Acute Respiratory Syndrome
Structure-based virtual screening suggests inhibitors of 3-Chymotrypsin-Like Protease of SARS-CoV-2 from Vernonia amygdalina and Occinum gratissimum.
Severe Acute Respiratory Syndrome
Synthesis of glutamic acid and glutamine peptides possessing a trifluoromethyl ketone group as SARS-CoV 3CL protease inhibitors.
Severe Acute Respiratory Syndrome
The Inhibitory Effects of Plant Derivate Polyphenols on the Main Protease of SARS Coronavirus 2 and Their Structure-Activity Relationship.
Severe Acute Respiratory Syndrome
The Leader Proteinase of Foot-and-Mouth Disease Virus Negatively Regulates the Type I Interferon Pathway by Acting as a Viral Deubiquitinase.
Severe Acute Respiratory Syndrome
Transmembrane serine protease 2 Polymorphisms and Susceptibility to Severe Acute Respiratory Syndrome Coronavirus Type 2 Infection: A German Case-Control Study.
Severe Acute Respiratory Syndrome
TRP channels in COVID-19 disease: Potential targets for prevention and treatment.
Severe Acute Respiratory Syndrome
Viral Proteases as Targets for Coronavirus Disease 2019 Drug Development.
Severe Acute Respiratory Syndrome
Why blood group A individuals are at risk whereas blood group O individuals are protected from SARS-CoV-2 (COVID-19) infection: A hypothesis regarding how the virus invades the human body via ABO(H) blood group-determining carbohydrates.
Sexually Transmitted Diseases
Antimicrobial peptides of the vaginal innate immunity and their role in the fight against sexually transmitted diseases.
Sexually Transmitted Diseases
Levels of vaginal secretory leukocyte protease inhibitor are decreased in women with lower reproductive tract infections.
Shock, Septic
Activated protein C downregulates p38 mitogen-activated protein kinase and improves clinical parameters in an in-vivo model of septic shock.
Shock, Septic
Acute stress response in children with meningococcal sepsis: important differences in the growth hormone/insulin-like growth factor I axis between nonsurvivors and survivors.
Shock, Septic
Association of phenotypic and genotypic characteristics of invasive Streptococcus pyogenes isolates with clinical components of streptococcal toxic shock syndrome.
Shock, Septic
Effects of Silver Sulphadiazine on Production of Extracellular Proteins by Strains of Staphylococcus Aureus Isolated from Burns Wound.
Shock, Septic
Hemodynamic, renal, and hormonal actions of aprotinin in an ovine model of septic shock.
Shock, Septic
Human C1-Inhibitor Suppresses Malaria Parasite Invasion and Cytoadhesion via Binding to Parasite Glycosylphosphatidylinositol and Host Cell Receptors.
Shock, Septic
Influence of aprotinin, a protease inhibitor, on porcine E. coli shock. Studies on coagulation, fibrinolytic and hemodynamic response.
Shock, Septic
Inhibition of lipopolysaccharide-induced tissue factor expression in monocytes by urinary trypsin inhibitor in vitro and in vivo.
Shock, Septic
Nafamostat mesilate, a serine protease inhibitor, suppresses lipopolysaccharide-induced nitric oxide synthesis and apoptosis in cultured human trophoblasts.
Shock, Septic
Negative regulation of inducible nitric-oxide synthase expression mediated through transforming growth factor-beta-dependent modulation of transcription factor TCF11.
Shock, Septic
Recombinant antitrypsin Pittsburgh undergoes proteolytic cleavage during E. coli sepsis and fails to prevent the associated coagulopathy in a primate model.
Shock, Septic
Recombinant C1 inhibitor P5/P3 variants display resistance to catalytic inactivation by stimulated neutrophils.
Shock, Septic
Successful treatment with continuous enteral protease inhibitor in a patient with severe septic shock.
Shock, Septic
Treatment of septic shock with a protease inhibitor in a canine model: a prospective, randomized, controlled trial.
Shock, Septic
Ulinastatin Protects Against LPS-Induced Acute Lung Injury by Attenuating TLR4/NF-?B Pathway Activation and Reducing Inflammatory Mediators.
Shock, Septic
Urinary trypsin inhibitor reduces inflammatory response in kidney induced by lipopolysaccharide.
Shock, Septic
Vaccine based on a ubiquitous cysteinyl protease and streptococcal pyrogenic exotoxin A protects against Streptococcus pyogenes sepsis and toxic shock.
Shock, Septic
[Clinico-experimental analysis of backgrounds of the severe surgical infections]
Shock, Septic
[Methicillin resistance, production of toxic shock syndrome toxin-1 and types of enterotoxin, protease and coagulase at vaginal isolates of Staphylococcus aureus]
Shock, Septic
[Protective effects of a protease inhibitor, urinastatin, on endotoxin shock and its scavenging effect on oxygen-derived free radicals]
Shock, Septic
[The effect of the protease inhibitor FUT-175 on phospholipase A2, complement, prostaglandins and prekallikrein during endotoxin shock]
Shwartzman Phenomenon
Contribution of Protein Z and Protein Z-Dependent Protease Inhibitor in Generalized Shwartzman Reaction.
Silicosis
[Changes in serum protease and cytokine in patients with silicosis, tuberculosis, and lung cancer].
Silicosis
[Status of the protease inhibitor system in patients with dust-induced lung diseases]
Simian Acquired Immunodeficiency Syndrome
Molecular cloning of a type D retrovirus from human cells (PMFV) and its homology to simian acquired immunodeficiency type D retroviruses.
Sinusitis
Chronic sinusitis and alpha1-antitrypsin deficiency: potential role for protease in rhinosinusitis?
Sinusitis
Lysosomal proteases and protease inhibitors in nasal allergy and non-atopic sinusitis.
Skin Diseases
A fluorescence lifetime-based assay for protease inhibitor profiling on human kallikrein 7.
Skin Diseases
A heterozygous null mutation combined with the G1258A polymorphism of SPINK5 causes impaired LEKTI function and abnormal expression of skin barrier proteins.
Skin Diseases
Clinical Expression and New SPINK5 Splicing Defects in Netherton Syndrome: Unmasking a Frequent Founder Synonymous Mutation and Unconventional Intronic Mutations.
Skin Diseases
Correlation between SPINK5 Gene Mutations and Clinical Manifestations in Netherton Syndrome Patients.
Skin Diseases
Engineered protease inhibitors based on sunflower trypsin inhibitor-1 (SFTI-1) provide insights into the role of sequence and conformation in Laskowski mechanism inhibition.
Skin Diseases
Expression of cathepsin L and its inhibitor hurpin in inflammatory and neoplastic skin diseases.
Skin Diseases
Generation of a quenched phosphonate activity-based probe for labelling the active KLK7 protease.
Skin Diseases
Human elastase 1: evidence for expression in the skin and the identification of a frequent frameshift polymorphism.
Skin Diseases
Human involucrin promoter mediates repression-resistant and compartment-specific LEKTI expression.
Skin Diseases
Identification of lympho-epithelial Kazal-type inhibitor 2 in human skin as a kallikrein-related peptidase 5-specific protease inhibitor.
Skin Diseases
In situ localization of HuHF serine protease mRNA and cytotoxic cell-associated antigens in human dermatoses. A novel method for the detection of cytotoxic cells in human tissues.
Skin Diseases
Interplay of Staphylococcal and Host Proteases Promotes Skin Barrier Disruption in Netherton Syndrome.
Skin Diseases
KLK5 and KLK7 Ablation Fully Rescues Lethality of Netherton Syndrome-Like Phenotype.
Skin Diseases
MALT1 Protease Activity Controls the Expression of Inflammatory Genes in Keratinocytes upon Zymosan Stimulation.
Skin Diseases
Multifunctional Serine Protease Inhibitor-Coated Water-Soluble Gold Nanoparticles as a Novel Targeted Approach for the Treatment of Inflammatory Skin Diseases.
Skin Diseases
Serine protease inhibitors to treat inflammation: a patent review (2011-2016).
Skin Diseases
Skin mast cell promotion of matrix remodeling in burn wound healing in mice: relevance of chymase.
Skin Diseases
Studies on the protease inhibitor in human blood. III. Clinical evaluation of the inhibitor in various skin diseases.
Skin Diseases
Toll-like receptor signaling induces the expression of lympho-epithelial Kazal-type inhibitor in epidermal keratinocytes.
Skin Diseases, Genetic
Elastase 2 is expressed in human and mouse epidermis and impairs skin barrier function in Netherton syndrome through filaggrin and lipid misprocessing.
Skin Diseases, Genetic
Intercellular Skin Barrier Lipid Composition and Organization in Netherton Syndrome Patients.
Skin Diseases, Genetic
Kallikrein 5 induces atopic dermatitis-like lesions through PAR2-mediated thymic stromal lymphopoietin expression in Netherton syndrome.
Skin Diseases, Genetic
SPINK5 knockdown in organotypic human skin culture as a model system for Netherton syndrome: effect of genetic inhibition of serine proteases kallikrein 5 and kallikrein 7.
Skin Diseases, Genetic
Transgenic kallikrein 5 mice reproduce major cutaneous and systemic hallmarks of Netherton syndrome.
Skin Neoplasms
Growth inhibition of mouse autochthonous skin cancer by oral administration of new serine protease inhibitor ONO-3403.
Skin Neoplasms
Increased inflammation delays wound healing in mice deficient in collagenase-2 (MMP-8).
Skin Neoplasms
Low levels of urokinase plasminogen activator components in basal cell carcinoma of the skin.
Sleep Apnea, Obstructive
Changes in four plasma adipokines before and after sleep in OSAS patients.
Sleep Apnea, Obstructive
CONSENSUS STATEMENT BY THE AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS AND AMERICAN COLLEGE OF ENDOCRINOLOGY ON THE COMPREHENSIVE TYPE 2 DIABETES MANAGEMENT ALGORITHM - 2019 EXECUTIVE SUMMARY.
Sleep Apnea, Obstructive
CONSENSUS STATEMENT BY THE AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS AND AMERICAN COLLEGE OF ENDOCRINOLOGY ON THE COMPREHENSIVE TYPE 2 DIABETES MANAGEMENT ALGORITHM - 2020 EXECUTIVE SUMMARY.
Sleep Apnea, Obstructive
Effect of the duration of protease inhibitor therapy in HIV-infected individuals on the severity of obstructive sleep apnea.
Sleep Deprivation
Angiotensin I-converting enzyme (ACE) activity and expression in rat central nervous system after sleep deprivation.
Sleep Initiation and Maintenance Disorders
Diagnosis of prion diseases by RT-QuIC results in improved surveillance.
Sleep Initiation and Maintenance Disorders
Sporadic and familial CJD: classification and characterisation.
Small Cell Lung Carcinoma
Hypoxia-inducible factor-1 alpha in non small cell lung cancer: relation to growth factor, protease and apoptosis pathways.
Small Cell Lung Carcinoma
Modification of beta-2-microglobulin in sera from patients with small cell lung cancer: evidence for involvement of a serine protease.
Small Cell Lung Carcinoma
Protease inhibitors suppress in vitro growth of human small cell lung cancer.
Small Fiber Neuropathy
Neuropathic pain in HIV patients receiving ART without stavudine in an Indonesia Referral Hospital.
Soft Tissue Injuries
Complexing of tissue plasminogen activator with PAI-1, alpha 2-macroglobulin, and C1-inhibitor: studies in patients with defibrination and a fibrinolytic state after electroshock or complicated labor.
Soft Tissue Injuries
The effects of protease supplementation on skeletal muscle function and DOMS following downhill running.
Spastic Paraplegia, Hereditary
ATPase and Protease Domain Movements in the Bacterial AAA+ Protease FtsH Are Driven by Thermal Fluctuations.
Spastic Paraplegia, Hereditary
Chaperone-like activity of the AAA domain of the yeast Yme1 AAA protease.
Spermatic Cord Torsion
Effects of gabexate mesilate on ischemia-reperfusion-induced testicular injury in rats.
Spinal Cord Injuries
A Novel 2-DE-Based Proteomic Analysis to Identify Multiple Substrates for Specific Protease in Neuronal Cells.
Spinal Cord Injuries
Alleviation of axonal damage in acute spinal cord injury by a protease inhibitor: automated morphometric analysis of drug-effects.
Spinal Cord Injuries
Beneficial effects of secretory leukocyte protease inhibitor after spinal cord injury.
Spinal Cord Injuries
Gabexate mesilate, a synthetic protease inhibitor, prevents compression-induced spinal cord injury by inhibiting activation of leukocytes in rats.
Spinal Cord Injuries
Genetic targeting of protease activated receptor 2 reduces inflammatory astrogliosis and improves recovery of function after spinal cord injury.
Spinal Cord Injuries
Higher calpastatin levels correlate with resistance to calpain-mediated proteolysis and neuronal apoptosis in juvenile rats after spinal cord injury.
Spinal Cord Injuries
Increased calpain I-mediated proteolysis, and preferential loss of dephosphorylated NF200, following traumatic spinal cord injury.
Spinal Cord Injuries
Looking downstream: the role of cyclic AMP-regulated genes in axonal regeneration.
Spinal Cord Injuries
Minocycline neuroprotects, reduces microgliosis, and inhibits caspase protease expression early after spinal cord injury.
Spinal Cord Injuries
Morphometric assessment of drug effects in experimental spinal cord injury.
Spinal Cord Injuries
Myosin heavy chain isoform and ubiquitin protease mRNA expression after passive leg cycling in persons with spinal cord injury.
Spinal Cord Injuries
Neutrophil elastase mediates acute pathogenesis and is a determinant of long-term behavioral recovery after traumatic injury to the immature brain.
Spinal Cord Injuries
Protein Degradome of Spinal Cord Injury: Biomarkers and Potential Therapeutic Targets.
Spinal Cord Injuries
Rapid calpain I activation and cytoskeletal protein degradation following traumatic spinal cord injury: attenuation with riluzole pretreatment.
Spinal Cord Injuries
Relatively low levels of calpain expression in juvenile rat correlate with less neuronal apoptosis after spinal cord injury.
Spinal Cord Injuries
Suppression of neurofilament degradation by protease inhibitors in experimental spinal cord injury.
Spinal Cord Injuries
The Inhibition of Inflammatory Signaling Pathway by Secretory Leukocyte Protease Inhibitor can Improve Spinal Cord Injury.
Spinal Cord Injuries
The Serine Protease Plasmin Cleaves the Amino-terminal Domain of the NR2A Subunit to Relieve Zinc Inhibition of the N-Methyl-D-aspartate Receptors.
Spinal Dysraphism
Allergic and latex-specific sensitization: route, frequency, and amount of exposure that are required to initiate IgE production.
Spinocerebellar Ataxias
Purkinje neuron Ca2+ influx reduction rescues ataxia in SCA28 model.
Spinocerebellar Ataxias
USP7, a ubiquitin-specific protease, interacts with ataxin-1, the SCA1 gene product.
Spinocerebellar Degenerations
Mutations in the mitochondrial protease gene AFG3L2 cause dominant hereditary ataxia SCA28.
Spinocerebellar Degenerations
Yet another gene mutation: dysfunction in mitochondrial protein quality control causing hereditary ataxia.
Spondylitis, Ankylosing
Lack of correlation between clinical disease activity and erythrocyte sedimentation rate, acute phase proteins or protease inhibitors in ankylosing spondylitis.
Spotted Fever Group Rickettsiosis
A Kunitz Protease Inhibitor from Dermacentor variabilis, a Vector for Spotted Fever Group Rickettsiae, Limits Rickettsia montanensis Invasion.
Squamous Cell Carcinoma of Head and Neck
A Novel Tumor Suppressor SPINK5 Serves as an Independent Prognostic Predictor for Patients with Head and Neck Squamous Cell Carcinoma.
Squamous Cell Carcinoma of Head and Neck
Binding of TGF-beta1 latency-associated peptide (LAP) to alpha(v)beta6 integrin modulates behaviour of squamous carcinoma cells.
Squamous Cell Carcinoma of Head and Neck
Cathepsin B mediates TRAIL-induced apoptosis in oral cancer cells.
Squamous Cell Carcinoma of Head and Neck
Cathepsin B promotes both motility and invasiveness of oral carcinoma cells.
Squamous Cell Carcinoma of Head and Neck
CEBPB knockdown sensitizes nasopharyngeal carcinoma cells to cisplatin by promoting the expression of serine protease inhibitor Kazal-type 5.
Squamous Cell Carcinoma of Head and Neck
Detection of oral squamous cell carcinoma metastasis with cathepsin D: An immunohistochemical approach.
Squamous Cell Carcinoma of Head and Neck
Downregulation of SERPINB13 expression in head and neck squamous cell carcinomas associates with poor clinical outcome.
Squamous Cell Carcinoma of Head and Neck
Effects of paclitaxel on permanent head and neck squamous cell carcinoma cell lines and identification of anti-apoptotic caspase 9b.
Squamous Cell Carcinoma of Head and Neck
Expression of the serine protease DESC1 correlates directly with normal keratinocyte differentiation and inversely with head and neck squamous cell carcinoma progression.
Squamous Cell Carcinoma of Head and Neck
Human papillomavirus infection in head and neck cancer: The role of the secretory leukocyte protease inhibitor.
Squamous Cell Carcinoma of Head and Neck
Laminin-derived peptide AG73 regulates migration, invasion, and protease activity of human oral squamous cell carcinoma cells through syndecan-1 and beta1 integrin.
Squamous Cell Carcinoma of Head and Neck
Loss of heterozygosity in mammary serine protease inhibitor (maspin) and p53 at chromosome 17 and 18 in oral cavity squamous cell carcinoma.
Squamous Cell Carcinoma of Head and Neck
Loss of membrane-bound serine protease inhibitor HAI-1 induces oral squamous cell carcinoma cells invasiveness.
Squamous Cell Carcinoma of Head and Neck
mRNA expression and hypermethylation of tumor suppressor genes apoptosis protease activating factor-1 and death-associated protein kinase in oral squamous cell carcinoma.
Squamous Cell Carcinoma of Head and Neck
Overexpression of protease nexin-1 mRNA and protein in oral squamous cell carcinomas.
Squamous Cell Carcinoma of Head and Neck
PAR-2 promotes cell proliferation, migration, and invasion through activating PI3K/AKT signaling pathway in oral squamous cell carcinoma.
Squamous Cell Carcinoma of Head and Neck
Predictive value of cathepsin-D for cervical lymph node metastasis in head and neck squamous cell carcinoma.
Squamous Cell Carcinoma of Head and Neck
Proteomic identification of serum biomarkers for head and neck cancer surveillance.
Squamous Cell Carcinoma of Head and Neck
Salivary protease spectrum biomarkers of oral cancer.
Squamous Cell Carcinoma of Head and Neck
Secretory leukocyte protease inhibitor (SLPI) expression and tumor invasion in oral squamous cell carcinoma.
Squamous Cell Carcinoma of Head and Neck
Secretory leukocyte protease inhibitor suppresses HPV E6-expressing HNSCC progression by mediating NF-?B and Akt pathways.
Squamous Cell Carcinoma of Head and Neck
Selective inhibition of NF-?B suppresses bone invasion by oral squamous cell carcinoma in vivo.
Squamous Cell Carcinoma of Head and Neck
Sentrin/small ubiquitin-like modifier-specific protease 5 protects oral cancer cells from oxidative stress-induced apoptosis.
Squamous Cell Carcinoma of Head and Neck
Serine protease inhibitor (SERPIN) B1 promotes oral cancer cell motility and is over-expressed in invasive oral squamous cell carcinoma.
Squamous Cell Carcinoma of Head and Neck
Structural Basis of Covalent Inhibitory Mechanism of TMPRSS2-Related Serine Proteases by Camostat.
Squamous Cell Carcinoma of Head and Neck
The antileukoprotease secretory leukocyte protease inhibitor (SLPI) and its role in the prevention of HPV-infections in head and neck squamous cell carcinoma.
Squamous Cell Carcinoma of Head and Neck
The deubiquitinase USP34 stabilizes SOX2 and induces cell survival and drug resistance in laryngeal squamous cell carcinoma.
Squamous Cell Carcinoma of Head and Neck
The level of secretory leukocyte protease inhibitor is decreased in metastatic head and neck squamous cell carcinoma.
Squamous Cell Carcinoma of Head and Neck
Ubiquitin-specific protease 14 promotes radio-resistance and suppresses autophagy in oral squamous cell carcinoma.
Squamous Cell Carcinoma of Head and Neck
Ubiquitin-specific protease 14 regulates cell proliferation and apoptosis in oral squamous cell carcinoma.
Squamous Cell Carcinoma of Head and Neck
Ubiquitin-specific protease 4 promotes TNF-?-induced apoptosis by deubiquitination of RIP1 in head and neck squamous cell carcinoma.
Squamous Cell Carcinoma of Head and Neck
USP9X Is Required to Maintain Cell Survival in Response to High-LET Radiation.
ST Elevation Myocardial Infarction
[Relationship between post-stenting coronary thrombolysis in myocardial infarction flow and plasma von Willebrand factor and ADAMTS-13 levels in patients with ST segment elevation myocardial infarction].
Staphylococcal Infections
[Protease inhibitors as immunomodulators in experimental acute pancreatitis and staphylococcal infection]
Staphylococcal Scalded Skin Syndrome
Plakoglobin rescues adhesive defects induced by ectodomain truncation of the desmosomal cadherin desmoglein 1: implications for exfoliative toxin-mediated skin blistering.
Staphylococcal Scalded Skin Syndrome
Purification of protease from a mixture of exfoliative toxin and newborn-mouse epidermis.
Staphylococcal Scalded Skin Syndrome
Staphylococcal scalded skin syndrome: exfoliative toxin A (ETA) induces serine protease activity when combined with A431 cells.
Starvation
8-Dehydrosterols induce membrane traffic and autophagy defects through V-ATPase dysfunction in Saccharomyces cerevisae.
Starvation
A metabolic study of the regulation of proteolysis by sugars in maize root tips: effects of glycerol and dihydroxyacetone.
Starvation
A Polyphosphate-Lon Protease Complex in the Adaptation of Escherichia coli to Amino Acid Starvation.
Starvation
A starvation-specific serine protease gene, isp6+, is involved in both autophagy and sexual development in Schizosaccharomyces pombe.
Starvation
AI-2 quorum sensing inhibitors affect the starvation response and reduce virulence in several Vibrio species, most likely by interfering with LuxPQ.
Starvation
Amino acid starvation induced by protease inhibition produces differential alterations in redox status and the thiol proteome in organogenesis-stage rat embryos and visceral yolk sacs.
Starvation
Appropriate leucine supplementation promotes glucose metabolism and enhances energy homeostasis in juvenile crucian carp (Carassius auratus gibelio var. CAS III).
Starvation
Autophagy in Tobacco Suspension-Cultured Cells in Response to Sucrose Starvation.
Starvation
Autoproteolytic activation of the haloalkaliphilic archaeon Natronococcus occultus extracellular serine protease.
Starvation
Brain-midgut short neuropeptide F mechanism that inhibits digestive activity of the American cockroach, Periplaneta americana upon starvation.
Starvation
Cell death of AKR-2B fibroblasts after serum removal: a process between apoptosis and necrosis.
Starvation
Changes in cysteine protease activity and localization during midgut metamorphosis in the crucifer root maggot (Delia radicum).
Starvation
Characterization of regulatory non-catalytic hexokinases in Aspergillus nidulans.
Starvation
Cinnamaldehyde and cinnamaldehyde derivatives reduce virulence in Vibrio spp. by decreasing the DNA-binding activity of the quorum sensing response regulator LuxR.
Starvation
Distinct Contribution of the HtrA Protease and PDZ Domains to Its Function in Stress Resilience and Virulence of Bacillus anthracis.
Starvation
Distinct roles for the p53-like transcription factor XprG and autophagy genes in the response to starvation.
Starvation
Effect of heat-shock & nutritional stress on the expression of a neutral thiol protease in Leishmania donovani promastigotes.
Starvation
Effect of nutritional conditions on extracellular protease production by the haloalkaliphilic archaeon Natrialba magadii.
Starvation
Effect of prolonged starvation on the activities of malic enzyme and acetylcholinesterase in tissues of Japanese quail.
Starvation
Effect of starvation and refeeding on activity of a Ca2+-dependent protease in rat skeletal muscle.
Starvation
Energetic reserves and digestive enzyme activities in juveniles of the red claw crayfish Cherax quadricarinatus nearby the point-of-no-return
Starvation
Genes for a nuclease and a protease are involved in the drastic decrease in cellular RNA amount in fission yeast cells during nitrogen starvation.
Starvation
Hepatitis B Virus X protein elevates Parkin-mediated mitophagy through Lon Peptidase in starvation.
Starvation
HicA of Escherichia coli defines a novel family of translation-independent mRNA interferases in bacteria and archaea.
Starvation
Improvement of recombinant hGM-CSF production by suppression of cysteine proteinase gene expression using RNA interference in a transgenic rice culture.
Starvation
Leaf senescence and nitrogen remobilization efficiency in oilseed rape (Brassica napus L.).
Starvation
Lon protease promotes survival of Escherichia coli during anaerobic glucose starvation.
Starvation
LONP1 Regulates Mitochondrial Accumulations of HMGB1 and Caspase-3 in CA1 and PV Neurons Following Status Epilepticus.
Starvation
Mature ribosomes are selectively degraded upon starvation by an autophagy pathway requiring the Ubp3p/Bre5p ubiquitin protease.
Starvation
Mutations in genes encoding sorting nexins alter production ofintracellular and extracellular proteases in Aspergillus nidulans.
Starvation
Protease inhibitors: recent advancement in its usage as a potential bio-control agent for insect pest management.
Starvation
Quantification of protease, amylase and lipase in the gut of Schizodactylus monstrosus during the postembryonic developmental stage. Effect of starvation, stress and topical application of juvenile hormone analogue.
Starvation
Regulation of exocellular protease in Neurospora crassa: induction and repression under conditions of nitrogen starvation.
Starvation
Role of Clp protease subunits in degradation of carbon starvation proteins in Escherichia coli.
Starvation
Role of inorganic polyphosphate in promoting ribosomal protein degradation by the Lon protease in E. coli.
Starvation
Structural basis of degradation signal recognition by SspB, a specificity-enhancing factor for the ClpXP proteolytic machine.
Starvation
The interaction of induction, repression and starvation in the regulation of extracellular proteases in Aspergillus nidulans: evidence for a role for CreA in the response to carbon starvation.
Starvation
The Stringent Response Promotes Antibiotic Resistance Dissemination by Regulating Integron Integrase Expression in Biofilms.
Starvation
Toxin-antitoxin loci as stress-response-elements: ChpAK/MazF and ChpBK cleave translated RNAs and are counteracted by tmRNA.
Starvation
Two intercellular signals required for fruiting body formation in Myxococcus xanthus act sequentially but non-hierarchically.
Status Asthmaticus
Alpha 1-antitrypsin deficiency and status asthmaticus in a black teen-ager.
Status Epilepticus
CDDO-Me Selectively Attenuates CA1 Neuronal Death Induced by Status Epilepticus via Facilitating Mitochondrial Fission Independent of LONP1.
Status Epilepticus
LONP1 Regulates Mitochondrial Accumulations of HMGB1 and Caspase-3 in CA1 and PV Neurons Following Status Epilepticus.
Steatorrhea
In vitro studies of the effects of HAART drugs and excipients on activity of digestive enzymes.
Stevens-Johnson Syndrome
Severe cutaneous reactions associated with the use of human immunodeficiency virus medications.
Stomach Diseases
Sulglycotide effect on the proteolytic and lipolytic activities of Helicobacter pylori toward gastric mucus.
Stomach Neoplasms
Anti-cancer activity of the novel 2-hydroxydiarylamide derivatives IMD-0354 and KRT1853 through suppression of cancer cell invasion, proliferation, and survival mediated by TMPRSS4.
Stomach Neoplasms
Asparaginyl endopeptidase promotes the invasion and metastasis of gastric cancer through modulating epithelial-to-mesenchymal transition and analysis of their phosphorylation signaling pathways.
Stomach Neoplasms
c-erbB-2 is of independent prognostic relevance in gastric cancer and is associated with the expression of tumor-associated protease systems.
Stomach Neoplasms
CD87-positive tumor cells in bone marrow aspirates identified by confocal laser scanning fluorescence microscopy.
Stomach Neoplasms
Changes in plasma levels of protease inhibitors to the degree of metastasis and prognosis of gastric cancer.
Stomach Neoplasms
Dehydroeffusol effectively inhibits human gastric cancer cell-mediated vasculogenic mimicry with low toxicity.
Stomach Neoplasms
Development of Chemical Tools to Monitor Human Kallikrein 13 (KLK13) Activity.
Stomach Neoplasms
Downregulation of A disintegrin and metallopeptidase with thrombospondin motif type 1 by DNA hypermethylation in human gastric cancer.
Stomach Neoplasms
Effect of inhibitors of cysteine and serine proteases in anticancer drug-induced apoptosis in gastric cancer cells.
Stomach Neoplasms
Exploitation of interleukin-18 by gastric cancers for their growth and evasion of host immunity.
Stomach Neoplasms
Genomic structure and chromosomal localization of the human hepatocyte growth factor activator inhibitor type 1 and 2 genes.
Stomach Neoplasms
Hepatocyte growth factor activator inhibitor type 2 lacking the first Kunitz-type serine proteinase inhibitor domain is a predominant product in mouse but not in human.
Stomach Neoplasms
Identification of a high molecular weight kininogen fragment as a marker for early gastric cancer by serum proteome analysis.
Stomach Neoplasms
Inhibition of Nuclear Factor-?B Enhances the Antitumor Effect of Paclitaxel Against Gastric Cancer with Peritoneal Dissemination in Mice.
Stomach Neoplasms
Loss of prostasin (PRSS8) in human bladder transitional cell carcinoma cell lines is associated with epithelial-mesenchymal transition (EMT).
Stomach Neoplasms
miR-133a, directly targeted USP39, suppresses cell proliferation and predicts prognosis of gastric cancer.
Stomach Neoplasms
Oncogenic USP22 supports gastric cancer growth and metastasis by activating c-Myc/NAMPT/SIRT1-dependent FOXO1 and YAP signaling.
Stomach Neoplasms
Overexpression and Biological Function of Ubiquitin-Specific Protease 42 in Gastric Cancer.
Stomach Neoplasms
Overexpression of a secretory leukocyte protease inhibitor in human gastric cancer.
Stomach Neoplasms
Overexpression of Testes-Specific Protease 50 (TSP50) Predicts Poor Prognosis in Patients with Gastric Cancer.
Stomach Neoplasms
Possible involvement of inositol 1,4,5-trisphosphate receptor type 3 (IP3R3) in the peritoneal dissemination of gastric cancers.
Stomach Neoplasms
Prognostic significance of SERPINE2 in gastric cancer and its biological function in SGC7901 cells.
Stomach Neoplasms
Prognostic significance of tissue-type plasminogen activator (tPA) content in gastric cancer and surrounding mucosa.
Stomach Neoplasms
Protein Z/protein Z-dependent protease inhibitor system in loco in human gastric cancer.
Stomach Neoplasms
Proteomic analysis revealed a strong association of a high level of alpha1-antitrypsin in gastric juice with gastric cancer.
Stomach Neoplasms
Rationales for expression and altered expression of apoptotic protease activating factor-1 gene in gastric cancer.
Stomach Neoplasms
Secretory leukocyte protease inhibitor is associated with MMP-2 and MMP-9 to promote migration and invasion in SNU638 gastric cancer cells.
Stomach Neoplasms
Seprase, a membrane-type serine protease, has different expression patterns in intestinal- and diffuse-type gastric cancer.
Stomach Neoplasms
Serum insulin-like growth factors (IGFs) and IGF binding protein (IGFBP)-3 in patients with gastric cancer: IGFBP-3 protease activity induced by surgery.
Stomach Neoplasms
SUMO-specific protease 2-mediated deSUMOylation is required for NDRG2 stabilization in gastric cancer cells.
Stomach Neoplasms
Testes-specific protease 50 (TSP50) promotes invasion and metastasis by inducing EMT in gastric cancer.
Stomach Neoplasms
The effect of disintegrin-metalloproteinase ADAM9 in gastric cancer progression.
Stomach Neoplasms
The expression of TMPRSS4 and Erk1 correlates with metastasis and poor prognosis in Chinese patients with gastric cancer.
Stomach Neoplasms
The role of urokinase-type plasminogen activator and its inhibitor PAI-1 in gastric cancer.
Stomach Neoplasms
TNF-alpha induces apoptosis mediated by AEBSF-sensitive serine protease(s) that may involve upstream caspase-3/CPP32 protease activation in a human gastric cancer cell line.
Stomach Neoplasms
Tumor-associated proteases and inhibitors in gastric cancer: analysis of prognostic impact and individual risk protease patterns.
Stomach Neoplasms
Ubiquitin-specific protease 15 contributes to gastric cancer progression by regulating the Wnt/?-catenin signaling pathway.
Stomach Neoplasms
Upregulation of HGF activator inhibitor type 1 but not type 2 along with regeneration of intestinal mucosa.
Stomach Neoplasms
USP22 maintains gastric cancer stem cell stemness and promotes gastric cancer progression by stabilizing BMI1 protein.
Stomach Neoplasms
[Activity of cathepsin D in the blood serum and urine of patients with cancer of the stomach, pancreas and liver]
Stomach Ulcer
Bauhinia Protease Inhibitors Attenuate Gastric Ulcer by Blocking Neutrophil Enzymes.
Stomach Ulcer
Role of basic fibroblast growth factor in the suppression of apoptotic caspase-3 during chronic gastric ulcer healing.
Stomach Ulcer
[Spectrum of acid proteases in the gastric juice of dogs in the normal state and in experimental atophan-induced stomach ulcer]
Stomatitis
Prophylactic action of allopurinol against chemotherapy-induced stomatitis--inhibition of superoxide dismutase and proteases.
Stomatitis
Quantitative determination of salivary components in the pellicle on PMMA denture base material.
Stomatitis
[Implications of antiretroviral therapy in oral medicine--a review of literature]
Streptococcal Infections
The IL-8 protease SpyCEP/ScpC of group A Streptococcus promotes resistance to neutrophil killing.
Striatonigral Degeneration
Increased M-calpain expression in the mesencephalon of patients with Parkinson's disease but not in other neurodegenerative disorders involving the mesencephalon: a role in nerve cell death?
Stroke
3K3A-activated protein C blocks amyloidogenic BACE1 pathway and improves functional outcome in mice.
Stroke
A Novel 2-DE-Based Proteomic Analysis to Identify Multiple Substrates for Specific Protease in Neuronal Cells.
Stroke
Analysis of the substrate specificity of Factor VII activating protease (FSAP) and design of specific and sensitive peptide substrates.
Stroke
Cardiovascular disease and use of contemporary protease inhibitors: the D:A:D international prospective multicohort study.
Stroke
Cellular localization and enzymatic activity of cathepsin B after spinal cord injury in the rat.
Stroke
Contribution of extracellular proteolysis and microglia to intracerebral hemorrhage.
Stroke
Detection of truncated isoforms of human neuroserpin lacking the reactive center loop: Implications in noninhibitory role.
Stroke
Endogenous activated protein C predicts hemorrhagic transformation and mortality after tissue plasminogen activator treatment in stroke patients.
Stroke
Extracellular Matrix Modulation Is Driven by Experience-Dependent Plasticity During Stroke Recovery.
Stroke
Genome-Wide Association Analysis of Young-Onset Stroke Identifies a Locus on Chromosome 10q25 Near HABP2.
Stroke
High levels of von Willebrand factor and low levels of its cleaving protease, ADAMTS13, are associated with stroke in young HIV-infected patients.
Stroke
Immunohistochemical study of cerebral amyloid angiopathy. III. Widespread Alzheimer A4 peptide in cerebral microvessel walls colocalizes with gamma trace in patients with leukoencephalopathy.
Stroke
Immunoreactive A4 and gamma-trace peptide colocalization in amyloidotic arteriolar lesions in brains of patients with Alzheimer's disease.
Stroke
Inflammation and stroke: therapeutic effects of adenoviral expression of secretory Leukocyte Protease Inhibitor.
Stroke
Inhibition of Cathepsins B Induces Neuroprotection Against Secondary Degeneration in Ipsilateral Substantia Nigra After Focal Cortical Infarction in Adult Male Rats.
Stroke
Involvement of Matrix Metalloproteinase 9 in Vertebral Arterial Dissection With Posterior Circulation Ischemic Stroke.
Stroke
Mannan binding lectin-associated serine protease-2 (MASP-2) critically contributes to post-ischemic brain injury independent of MASP-1.
Stroke
Molecular Implications of Natriuretic Peptides in the Protection from Hypertension and Target Organ Damage Development.
Stroke
Nafamostat Mesilate Improves Neurological Outcome and Axonal Regeneration after Stroke in Rats.
Stroke
Nanoparticles That Sense Thrombin Activity As Synthetic Urinary Biomarkers of Thrombosis.
Stroke
Progress and prospect of single-molecular ClpX ATPase researching system-a mini-review.
Stroke
Protease activated receptor 4 (PAR4) antagonists: Research progress on small molecules in the field of antiplatelet agents.
Stroke
Protease activated receptor-1 mediates cytotoxicity during ischemia using in vivo and in vitro models.
Stroke
Protease activated receptors (PAR)-1 and -2 mediate cellular effects of factor VII activating protease (FSAP).
Stroke
Protease protection assays show polypeptide movement into the SecY channel by power strokes of the SecA ATPase.
Stroke
Protease-independent action of tissue plasminogen activator in brain plasticity and neurological recovery after ischemic stroke.
Stroke
Protective role of tuftsin fragment 1-3 in an animal model of intracerebral hemorrhage.
Stroke
Proteomic Protease Substrate Profiling of tPA Treatment in Acute Ischemic Stroke Patients: A Step Toward Individualizing Thrombolytic Therapy at the Bedside.
Stroke
Purification and functional characterisation of Rhinocerase, a novel serine protease from the venom of Bitis gabonica rhinoceros.
Stroke
Smad3-dependent induction of plasminogen activator inhibitor-1 in astrocytes mediates neuroprotective activity of transforming growth factor-beta 1 against NMDA-induced necrosis.
Stroke
Soluble expression of active recombinant human tissue plasminogen activator derivative (K2S) in Escherichia coli.
Stroke
Stroke-induced subventricular zone proliferation is promoted by tumor necrosis factor-alpha-converting enzyme protease activity.
Stroke
Survey of plasma proteins in children with progeria pre-therapy and on-therapy with lonafarnib.
Stroke
Synthesis and evaluation of novel and potent protease activated receptor 4 (PAR4) antagonists based on a quinazolin-4(3H)-one scaffold.
Stroke
TFPI inhibits lectin pathway of complement activation by direct interaction with MASP-2.
Stroke
The complexity of tissue-type plasminogen activator: can serine protease inhibitors help in stroke management?
Stroke
The role of neutrophils in mediating stroke injury in the diabetic db/db mouse brain following hypoxia-ischemia.
Stroke
Thrombin induces long-term potentiation of reactivity to afferent stimulation and facilitates epileptic seizures in rat hippocampal slices: toward understanding the functional consequences of cerebrovascular insults.
Stroke
Tissue plasminogen activator (tPA) deficiency exacerbates cerebrovascular fibrin deposition and brain injury in a murine stroke model: studies in tPA-deficient mice and wild-type mice on a matched genetic background.
Stroke
Tissue plasminogen activator contributes to morphine tolerance and induces mechanical allodynia via astrocytic IL-1? and ERK signaling in the spinal cord of mice.
Stroke
Tissue Plasminogen Activator Expression Is Restricted to Subsets of Excitatory Pyramidal Glutamatergic Neurons.
Stroke
[Does transforming growth factor-beta (TGF-beta) act as a neuroprotective agent in cerebral ischemia?]
Subarachnoid Hemorrhage
Broad-spectrum and selective serine protease inhibitors prevent expression of platelet-derived growth factor-BB and cerebral vasospasm after subarachnoid hemorrhage: vasospasm caused by cisternal injection of recombinant platelet-derived growth factor-BB.
Subarachnoid Hemorrhage
Combination of serine protease inhibitor FUT-175 and thromboxane synthetase inhibitor OKY-046 decreases cerebral vasospasm in patients with subarachnoid hemorrhage.
Subarachnoid Hemorrhage
Effects of protease inhibitor and immunosuppressant on cerebral vasospasm after subarachnoid hemorrhage in rabbits.
Subarachnoid Hemorrhage
Polymorphism rs4934 of SERPINA3 and sporadic intracranial aneurysms in the Chinese population.
Subarachnoid Hemorrhage
Preventive effect of synthetic serine protease inhibitor, FUT-175, on cerebral vasospasm in rabbits.
Subarachnoid Hemorrhage
Should we use the serum vaspin level for the diagnosis and/or prognosis of subarachnoid hemorrhage?
Subarachnoid Hemorrhage
Therapeutic trial of cerebral vasospasm with the serine protease inhibitor, FUT-175, administered in the acute stage after subarachnoid hemorrhage.
Sunburn
Stimulatory effect of topical application of caffeine on UVB-induced apoptosis in mouse skin.
Superinfection
Early multi-system organ failure associated with acute pancreatitis: a plea for a conservative therapeutic strategy.
Superinfection
HIV medicine after Barcelona conference: interview with Howard Grossman, M.D. Interview by John S. James.
Superinfection
Lack of detectable human immunodeficiency virus type 1 superinfection during 1072 person-years of observation.
Superinfection
Rubella virus-induced superinfection exclusion studied in cells with persisting replicons.
Superinfection
Serine protease inhibitor kazal-type 6 inhibits tumorigenesis of human hepatocellular carcinoma cells via its extracellular action.
Superinfection
Superinfection exclusion of alphaviruses in three mosquito cell lines persistently infected with Sindbis virus.
Superinfection
[Changes in the protease activity in the lungs of mice infected with the influenza A virus]
Supranuclear Palsy, Progressive
Amyloid-beta deposition in the cerebral cortex in Dementia with Lewy bodies is accompanied by a relative increase in AbetaPP mRNA isoforms containing the Kunitz protease inhibitor.
Supranuclear Palsy, Progressive
Increased M-calpain expression in the mesencephalon of patients with Parkinson's disease but not in other neurodegenerative disorders involving the mesencephalon: a role in nerve cell death?
Syndactyly
A new mouse mutant with cleavage-resistant versican and isoform-specific versican mutants demonstrate that proteolysis at the Glu441-Ala442 peptide bond in the V1 isoform is essential for interdigital web regression.
Synucleinopathies
Alpha-synuclein degradation by serine protease neurosin: implication for pathogenesis of synucleinopathies.
Synucleinopathies
Low CSF levels of both ?-synuclein and the ?-synuclein cleaving enzyme neurosin in patients with synucleinopathy.
Syphilis
Immunization of rabbits with recombinant Treponema pallidum surface antigen 4D alters the course of experimental syphilis.
Syphilis
Sarcoidosis-related anterior uveitis in a patient with human immunodeficiency virus.
Systemic Vasculitis
Antibodies to selected minor target antigens in patients with anti-neutrophil cytoplasmic antibodies (ANCA).
Systemic Vasculitis
Detection of autoantibodies against myeloid lysosomal enzymes: a useful adjunct to classification of patients with biopsy-proven necrotizing arteritis.
Tachycardia, Ventricular
Monomorphic ventricular tachycardia due to protease inhibitor intoxication by atazanavir.
Tauopathies
Protease-resistant SOD1 aggregates in amyotrophic lateral sclerosis demonstrated by paraffin-embedded tissue (PET) blot.
TDP-43 Proteinopathies
TDP-43 induces mitochondrial damage and activates the mitochondrial unfolded protein response.
Tendinopathy
Cyclical strain modulates metalloprotease and matrix gene expression in human tenocytes via activation of TGF?
Tendinopathy
The effect of ciprofloxacin on tendon, paratenon, and capsular fibroblast metabolism.
Teratocarcinoma
A retinoic acid-inducible mRNA from F9 teratocarcinoma cells encodes a novel protease inhibitor homolog.
Teratocarcinoma
A retinoic acid-inducible mRNA from F9 teratocarcinoma cells encodes a novel protease inhibitor homologue.
Teratocarcinoma
Anti-sense inhibition of tissue plasminogen activator production in differentiated F9 teratocarcinoma cells.
Teratocarcinoma
Protease activity associated with loss of adhesiveness in mouse teratocarcinoma.
Teratoma
Fusion of the SUMO/Sentrin-specific protease 1 gene SENP1 and the embryonic polarity-related mesoderm development gene MESDC2 in a patient with an infantile teratoma and a constitutional t(12;15)(q13;q25).
Testicular Neoplasms
Localization, expression and genomic structure of the gene encoding the human serine protease testisin.
Testicular Neoplasms
Organization and chromosomal localization of the murine Testisin gene encoding a serine protease temporally expressed during spermatogenesis.
Tetanus
An in vitro assay for detection of tetanus neurotoxin activity: using antibodies for recognizing the proteolytically generated cleavage product.
Tetanus
Botulinum A like type B and tetanus toxins fulfils criteria for being a zinc-dependent protease.
Tetanus
Differences in the protease activities of tetanus and botulinum B toxins revealed by the cleavage of vesicle-associated membrane protein and various sized fragments.
Tetanus
Fusion complex formation protects synaptobrevin against proteolysis by tetanus toxin light chain.
Tetanus
Human monoclonal ScFv that inhibits cellular entry and metalloprotease activity of tetanus neurotoxin.
Tetanus
Interactions between synaptic vesicle fusion proteins explored by atomic force microscopy.
Tetanus
Intracellular distribution and functional importance of vesicle-associated membrane protein 2 in gastric parietal cells.
Tetanus
Lipid rafts act as specialized domains for tetanus toxin binding and internalization into neurons.
Tetanus
Mucosal immunization of mice using CpG DNA and/or mutants of the heat-labile enterotoxin of Escherichia coli as adjuvants.
Tetanus
Restoration of anti-tetanus toxoid responses in patients initiating highly active antiretroviral therapy with or without a boost immunization: an INITIO substudy.
Tetanus
Structural flexibility of the tetanus neurotoxin revealed by crystallographic and solution scattering analyses.
Tetanus
Structure of tetanus toxin. Demonstration and separation of a specific enzyme converting intracellular tetanus toxin to the extracellular form.
Tetanus
Tetanus toxin inhibits neuroexocytosis even when its Zn(2+)-dependent protease activity is removed.
Tetanus
Tetanus toxin is a zinc protein and its inhibition of neurotransmitter release and protease activity depend on zinc.
Tetanus
Tetanus toxin: biochemical and pharmacological comparison between its protoxin and some isotoxins obtained by limited proteolysis.
Tetanus
The role of cAMP in mucosal adjuvanticity of Escherichia coli heat-labile enterotoxin (LT).
Tetanus
The Stability of Glutamatergic Synapses Is Independent of Activity Level, but Predicted by Synapse Size.
Thrombocythemia, Essential
Plasma Concentrations of Protein Z and Protein Z-Dependent Protease Inhibitor in Patients With Essential Thrombocythemia.
Thrombocytopenia
Cleavage of anti-PF4/heparin IgG by a bacterial protease and potential benefit in heparin-induced thrombocytopenia.
Thrombocytopenia
Congenital microangiopathic hemolytic anemia and thrombocytopenia with unusually large von Willebrand factor multimers and von Willebrand factor-cleaving protease.
Thrombocytopenia
Efficacy of protease inhibitor-based anti-retroviral therapy in severe HIV-associated thrombocytopenia unresponsive to AZT.
Thrombocytopenia
Emerging roles of adjunct therapies in acquired thrombotic thrombocytopenia purpura.
Thrombocytopenia
Hemolytic uremic syndrome-associated Shiga toxins promote endothelial-cell secretion and impair ADAMTS13 cleavage of unusually large von Willebrand factor multimers.
Thrombocytopenia
Prasugrel and Acquired Thrombotic Thrombocytopenic Purpura Associated with ADAMTS13 Activity Deficiency.
Thrombocytopenia
Response of severe HIV-associated thrombocytopenia to highly active antiretroviral therapy including protease inhibitors.
Thrombocytopenia
Rituximab induces remission of cerebral ischemia caused by thrombotic thrombocytopenic purpura.
Thrombocytopenia
von Willebrand factor-cleaving protease (ADAMTS-13) activity determination in the diagnosis of thrombotic microangiopathies: the Swiss experience.
Thrombocytopenia
von Willebrand factor-cleaving protease inhibitor in a patient with human immunodeficiency syndrome-associated thrombotic thrombocytopenic purpura.
Thrombocytopenia
[Paediatric case report of an acquired autoimmune thrombotic thrombocytopenic purpura]
Thrombophilia
Hereditary thrombophilia: identification of nonsense and missense mutations in the protein C gene.
Thrombophilia
Increased von Willebrand factor over decreased ADAMTS-13 activity is associated with poor prognosis in patients with advanced non-small-cell lung cancer.
Thrombophilia
Is thrombosis a contributor to heart failure pathophysiology? Possible mechanisms, therapeutic opportunities, and clinical investigation challenges.
Thrombophilia
Mutations within the protein Z-dependent protease inhibitor gene are associated with venous thromboembolic disease: a new form of thrombophilia.
Thrombophilia
Nafamostat mesilate, a synthetic protease inhibitor, attenuated hypercoagulability in a canine model of hemorrhagic shock.
Thrombophilia
Protein Z and protein Z-dependent protease inhibitor. Determinants of levels and risk of venous thrombosis.
Thrombophilia
Viral load of the human immunodeficiency virus could be an independent risk factor for endothelial dysfunction.
Thrombophilia
Warm ischemia provokes inflammation and regional hypercoagulability within the heart during off-pump coronary artery bypass: a possible target for serine protease inhibition.
Thrombophlebitis
[TREATMENT OF INFLAMMATORY THROMBOPHLEBITIS WITH PROTEASE INHIBITOR FROM POTATO.]
Thrombosis
A hybrid plasminogen activator binds to the u-PA receptor and has a reduced thrombolytic potency in vivo.
Thrombosis
A novel near-infrared fluorescence sensor for detection of thrombin activation in blood.
Thrombosis
A rapid test for the diagnosis of thrombotic thrombocytopenic purpura using surface enhanced laser desorption/ionization time-of-flight (SELDI-TOF)-mass spectrometry.
Thrombosis
Amplified electrochemical aptasensor taking AuNPs based sandwich sensing platform as a model.
Thrombosis
Analysis of the substrate specificity of Factor VII activating protease (FSAP) and design of specific and sensitive peptide substrates.
Thrombosis
Antibodies to von Willebrand factor-cleaving protease in acute thrombotic thrombocytopenic purpura.
Thrombosis
Anticoagulant Dodecapeptide Suppresses Thrombosis In Vivo by Inhibiting the Thrombin Exosite-I Binding Site.
Thrombosis
Antithrombotic strategies targeting thrombin activities, thrombin receptors and thrombin generation.
Thrombosis
Asymmetric Synthesis of Silanediol Inhibitors for the Serine Protease Coagulation Cascade Enzyme FXIa.
Thrombosis
Biochemical analysis and investigation on the prospective applications of alkaline protease from a Bacillus cereus strain.
Thrombosis
Blocking of platelets or intrinsic coagulation pathway-driven thrombosis does not prevent cerebral infarctions induced by photothrombosis.
Thrombosis
Case report. Intestinal infarction due to vascular catastrophe in an HIV-infected patient.
Thrombosis
Characterization of polymorphic structure of cathepsin G gene: role in cardiovascular and cerebrovascular diseases.
Thrombosis
Cloning, purification and characterization of a recombinant protease with novel thrombolytic activity in human plasma and rat thrombosis models.
Thrombosis
Coagulation factor and protease pathways in thrombosis and cardiovascular disease.
Thrombosis
Comparative thrombolytic properties of tissue-type plasminogen activator (t-PA), single-chain urokinase-type plasminogen activator (u-PA) and K1K2Pu (a t-PA/u-PA chimera) in a combined arterial and venous thrombosis model in the dog.
Thrombosis
Comparison of the recombinant Escherichia coli-produced protease domain of tissue-type plasminogen activator with alteplase, reteplase and streptokinase in a canine model of coronary artery thrombolysis.
Thrombosis
Control of proliferation of human vascular endothelial cells. Characterization of the response of human umbilical vein endothelial cells to fibroblast growth factor, epidermal growth factor, and thrombin.
Thrombosis
Crystallization and preliminary crystallographic characterization of three peptidic inhibitors in complex with ?-thrombin.
Thrombosis
Deficiency of tPA Exacerbates White Matter Damage, Neuroinflammation, Glymphatic Dysfunction and Cognitive Dysfunction in Aging Mice.
Thrombosis
Development and validation of novel imaging technologies to assist translational studies in atherosclerosis.
Thrombosis
Development of a Hyperactive Primary Hemostatic System During Off-Pump Lung Transplantation Resulting From an Unbalance Between von Willebrand Factor and Its Cleaving Protease ADAMTS13.
Thrombosis
Development of proteinase-activated receptor 1 antagonists as therapeutic agents for thrombosis, restenosis and inflammatory diseases.
Thrombosis
Different DOACs Control Inflammation in Cardiac Ischemia-Reperfusion Differently.
Thrombosis
Effects of focal mild hypothermia on thrombin-induced brain edema formation and the expression of protease activated receptor-1, matrix metalloproteinase-9 and aquaporin 4 in rats.
Thrombosis
Endocytosis of the recombinant tissue plasminogen activator alteplase by hepatic endothelial cells.
Thrombosis
Epidemiology of thrombosis in HIV-infected individuals. The Adult/Adolescent Spectrum of HIV Disease Project.
Thrombosis
Epsilon Aminocaproic Acid Pretreatment Provides Neuroprotection Following Surgically Induced Brain Injury in a Rat Model.
Thrombosis
Extracellular protein disulfide isomerase regulates coagulation on endothelial cells through modulation of phosphatidylserine exposure.
Thrombosis
Factor VII-activating protease deficiency promotes neointima formation by enhancing leukocyte accumulation.
Thrombosis
Fibrinolytic protease from Bacillus cereus S46: Purification, characterization, and evaluation of its in vitro thrombolytic potential.
Thrombosis
High-level expression, purification, and enzymatic characterization of truncated human plasminogen (Lys531-Asn791) in the methylotrophic yeast Pichia pastoris.
Thrombosis
Human plasminogen catalytic domain undergoes an unusual conformational change upon activation.
Thrombosis
Improvement of the acid resistance, catalytic efficiency, and thermostability of nattokinase by multisite-directed mutagenesis.
Thrombosis
Improving the understanding of plasma kallikrein contribution to arterial thrombus formation using two plant protease inhibitors.
Thrombosis
In situ gene expression of urokinase-type plasminogen activator and its receptor in transitional cell carcinoma of the human bladder.
Thrombosis
In vitro comparison of complementary interactions between synthetic linear/branched oligo/poly-L-lysines and tissue plasminogen activator by means of high-performance monolithic-disk affinity chromatography.
Thrombosis
In Vivo Anticoagulant and Thrombolytic Activities of a Fibrinolytic Serine Protease (Brevithrombolase) With the k-Carrageenan-Induced Rat Tail Thrombosis Model.
Thrombosis
In vivo characterization of Lopap, a prothrombin activator serine protease from the Lonomia obliqua caterpillar venom.
Thrombosis
In vivo imaging analysis of the interaction between unusually large von Willebrand factor multimers and platelets on the surface of vascular wall.
Thrombosis
In vivo imaging of thrombin activity in experimental thrombi with thrombin-sensitive near-infrared molecular probe.
Thrombosis
In-vitro and in-vivo consequences of mutations in the von Willebrand factor cleaving protease ADAMTS13 in thrombotic thrombocytopenic purpura.
Thrombosis
Increased dipeptidyl peptidase-4 accelerates chronic stress-related thrombosis in a mouse carotid artery model.
Thrombosis
Inhibition of thrombin-induced neuronal cell death by recombinant thrombomodulin and E5510, a synthetic thrombin receptor signaling inhibitor.
Thrombosis
Inhibitory effects of ONO-3307 on various proteases and tissue thromboplastin in vitro and on experimental thrombosis in vivo.
Thrombosis
Interaction of the factor XIII activation peptide with alpha -thrombin. Crystal structure of its enzyme-substrate analog complex.
Thrombosis
Involvement of the mural thrombus as a site of protease release and activation in human aortic aneurysms.
Thrombosis
Is thrombosis a contributor to heart failure pathophysiology? Possible mechanisms, therapeutic opportunities, and clinical investigation challenges.
Thrombosis
Letter by Borst Regarding Article, "Rivaroxaban Reduces Arterial Thrombosis by Inhibition of FXa Driven Platelet Activation via Protease Activated Receptor-1".
Thrombosis
Letter by Violi et al Regarding Article, "Rivaroxaban Reduces Arterial Thrombosis by Inhibition of Fxa-Driven Platelet Activation via Protease Activated Receptor-1".
Thrombosis
Matrix Metalloproteinase 9 (MMP-9) Regulates Vein Wall Biomechanics in Murine Thrombus Resolution.
Thrombosis
Microspheres based on inulin for the controlled release of serine protease inhibitors: preparation, characterization and in vitro release.
Thrombosis
Modulation of osteoblast-like cell behavior by activation of protease-activated receptor-1.
Thrombosis
Modulation of thrombomodulin-dependent activation of human protein C through differential expression of endothelial Smads.
Thrombosis
Molecular analysis of a fibrin-degrading enzyme from Bacillus subtilis K2 isolated from the Indonesian soybean-based fermented food moromi.
Thrombosis
Molecular basis for the inhibition of human alpha-thrombin by the macrocyclic peptide cyclotheonamide A.
Thrombosis
Molecular recognition at the thrombin active site: structure-based design and synthesis of potent and selective thrombin inhibitors and the X-ray crystal structures of two thrombin-inhibitor complexes.
Thrombosis
Moving Up the Coagulation Cascade: Potential Factor X Inhibition for Percutaneous Coronary Intervention.
Thrombosis
Multifunctional Thrombin-Activatable Polymer Capsules for Specific Targeting to Activated Platelets.
Thrombosis
Multiple binding mode of reversible synthetic thrombin inhibitors. A comparative structural analysis.
Thrombosis
Nanoparticles That Sense Thrombin Activity As Synthetic Urinary Biomarkers of Thrombosis.
Thrombosis
Negative selectivity and the evolution of protease cascades: the specificity of plasmin for peptide and protein substrates.
Thrombosis
Normal levels of ADAMTS13 and factor H are present in the pharmaceutically licensed plasma for transfusion (Octaplas) and in the universally applicable plasma (Uniplas) in development.
Thrombosis
Novel Fibrinolytic Protease Producing Streptomyces radiopugnans VITSD8 from Marine Sponges.
Thrombosis
P1 and P2' site mutations convert protease nexin-2 from a factor XIa inhibitor to a plasmin inhibitor.
Thrombosis
P14ARF Suppresses Tumor-Induced Thrombosis by Regulating the Tissue Factor Pathway.
Thrombosis
Peptide Macrocycle Inhibitor of Coagulation Factor XII with Subnanomolar Affinity and High Target Selectivity.
Thrombosis
Plasminogen-induced foam cell formation by macrophages occurs through a histone 2B (H2B)-PAR1 pathway and requires integrity of clathrin-coated pits.
Thrombosis
Platelet factor 4 inhibits ADAMTS13 activity and regulates the multimeric distribution of von Willebrand factor.
Thrombosis
Portal vein thrombosis in a patient with HIV treated with a protease inhibitor-containing regimen.
Thrombosis
Prediction of enzyme binding: human thrombin inhibition study by quantum chemical and artificial intelligence methods based on X-ray structures.
Thrombosis
Pregnancy-associated plasma protein-A in atherosclerosis: Molecular marker, mechanistic insight, and therapeutic target.
Thrombosis
Primary Human Lung Alveolus-on-a-chip Model of Intravascular Thrombosis for Assessment of Therapeutics.
Thrombosis
Protease activated receptors (PAR)-1 and -2 mediate cellular effects of factor VII activating protease (FSAP).
Thrombosis
Protease activity in the multi-layered intra-luminal thrombus of abdominal aortic aneurysms.
Thrombosis
Protease-activated receptor-1 mediates thrombin-induced persistent sodium current in human cardiomyocytes.
Thrombosis
Protein C deficiency caused by homozygosity for a novel PROC D180G mutation--in vitro expression and structural analysis of the mutation.
Thrombosis
Protein Z and protein Z-dependent protease inhibitor. Determinants of levels and risk of venous thrombosis.
Thrombosis
Protein Z/Z-dependent protease inhibitor (PZ/ZPI) anticoagulant system and thrombosis.
Thrombosis
Proteome analysis of testis from infertile protein C inhibitor-deficient mice reveals novel changes in serpin processing and prostaglandin metabolism.
Thrombosis
Purification and Antithrombotic Potential of a Fibrinolytic Enzyme from Shiitake Culinary- Medicinal Mushroom, Lentinus edodes GNA01 (Agaricomycetes).
Thrombosis
Purification and characterization of a novel fibrinolytic protease from Fusarium sp. CPCC 480097.
Thrombosis
Purification of a fibrinolytic protease from Mucor subtilissimus UCP 1262 by aqueous two-phase systems (PEG/sulfate).
Thrombosis
Purification of serine protease from polychaeta, Lumbrineris nipponica, and assessment of its fibrinolytic activity.
Thrombosis
Rapid detection of a protein C gene mutation present in the asymptomatic and not in the thrombosis-prone lineage.
Thrombosis
Response by Petzold et al to Letter Regarding Article, "Rivaroxaban Reduces Arterial Thrombosis by Inhibition of FXa-Driven Platelet Activation via Protease Activated Receptor-1".
Thrombosis
Response by Petzold et al to Letter Regarding Article, "Rivaroxaban Reduces Arterial Thrombosis by Inhibition of Fxa-Driven Platelet Activation via Protease Activated Receptor-1".
Thrombosis
Response of the blood clotting system of the American horseshoe crab, Limulus polyphemus, to a novel form of lipopolysaccharide from a green alga.
Thrombosis
Review: thromboses among HIV-infected patients during the highly active antiretroviral therapy era.
Thrombosis
Rivaroxaban Reduces Arterial Thrombosis by Inhibition of FXa-Driven Platelet Activation via Protease Activated Receptor-1.
Thrombosis
Role of Tissue Factor in the Maternal Immunological Attack of the Embryo in the Antiphospholipid Syndrome.
Thrombosis
Serine and metalloprotease signaling through PAR1 in arterial thrombosis and vascular injury.
Thrombosis
Single Nucleotide Variant rs2232710 in the Protein Z-Dependent Protease Inhibitor (ZPI, SERPINA10) Gene Is Not Associated with Deep Vein Thrombosis.
Thrombosis
Smad6s regulates plasminogen activator inhibitor-1 through a protein kinase C-beta-dependent up-regulation of transforming growth factor-beta.
Thrombosis
Structural Basis for Activity and Specificity of an Anticoagulant Anti-FXIa Monoclonal Antibody and a Reversal Agent.
Thrombosis
Structural stability of human alpha-thrombin studied by disulfide reduction and scrambling.
Thrombosis
Structure-based design of residue 1 analogs of the direct thrombin inhibitor pentapeptide FM 19.
Thrombosis
Studies on Screening, Isolation and Purification of a Fibrinolytic Protease from an Isolate (VK12) of Ganoderma Lucidum and Evaluation of its Antithrombotic Activity.
Thrombosis
Synthesis, evaluation and structure-activity relationship of new 3-carboxamide coumarins as FXIIa inhibitors.
Thrombosis
The discovery and characterization of a novel nucleotide-based thrombin inhibitor.
Thrombosis
The effects of metal ions in Euphorbia cf. lactea latex on the fibrinogenolytic activity of a plant protease.
Thrombosis
The kunitz protease inhibitor domain of protease nexin-2 inhibits factor XIa and murine carotid artery and middle cerebral artery thrombosis.
Thrombosis
The pro-coagulant fibrinogenolytic serine protease isoenzymes purified from Daboia russelii russelii venom coagulate the blood through factor V activation: role of glycosylation on enzymatic activity.
Thrombosis
The role of protein Z and protein Z-dependent protease inhibitor polymorphisms in the development of prosthetic heart valve thrombosis.
Thrombosis
The Role of Protein Z and Protein Z-Dependent Protease Inhibitor Polymorphisms in the Development of Prosthetic Heart Valve Thrombosis.
Thrombosis
The single-chain form of tissue-type plasminogen activator has catalytic activity: studies with a mutant enzyme that lacks the cleavage site.
Thrombosis
The Thrombotic Profile of Treatment-Naive HIV-Positive Black South Africans With Acute Coronary Syndromes.
Thrombosis
The tissue-type plasminogen activator-plasminogen activator inhibitor 1 complex promotes neurovascular injury in brain trauma: evidence from mice and humans.
Thrombosis
Therapeutical potential of direct thrombin inhibitors for atherosclerotic vascular disease.
Thrombosis
Thrombin and its protease-activated receptor-1 (PAR1) participate in the endothelial-mesenchymal transdifferentiation process.
Thrombosis
Thrombin-induced IL-8/CXCL8 release is mediated by CK2, MSK1, and NF-?B pathways in human lung epithelial cells.
Thrombosis
Thrombolytic effect of a plasminogen-plasminogen activator chimera in a photochemically induced thrombosis (PIT) model.
Thrombosis
Thrombosis recanalization by paeoniflorin through the upregulation of urokinase?type plasminogen activator via the MAPK signaling pathway.
Thrombosis
Tissue-type plasminogen activator (tPA) in breast cancer: relationship with clinicopathological parameters and prognostic significance.
Thrombosis
Unexplained thrombosis in HIV-infected patients receiving protease inhibitors: report of seven cases.
Thrombosis
Von Willebrand Factor Adhesive Activity and ADAMTS13 Protease Activity in HIV-1-Infected Men.
Thrombosis
X-ray crystal structure of plasmin with tranexamic acid-derived active site inhibitors.
Thrombosis
[Balloon occlusion pulmonary angiography and anticoagulant-antithrombotic therapy in ARDS-associated pulmonary vascular thrombosis]
Thrombosis
[Clinical use of oral protease preparation "Dasen" in the treatment of retinal vein thrombosis and hyaloid hemorrhage]
Thrombotic Microangiopathies
Association between thrombotic microangiopathy and reduced ADAMTS13 activity in malignant hypertension.
Thrombotic Microangiopathies
Congenital thrombotic thrombocytopenic purpura caused by new compound heterozygous mutations of the ADAMTS13 gene.
Thrombotic Microangiopathies
Coombs Positive Thrombotic Thrombocytopenic Purpura in a Male Pediatric Patient: An Urgent Diagnostic Challenge.
Thrombotic Microangiopathies
Diagnosis and follow-up of thrombotic thrombocytopenic purpura with an automated chemiluminescent ADAMTS13 activity immunoassay.
Thrombotic Microangiopathies
Evaluation of a rapid turn-over, fully-automated ADAMTS13 activity assay: a method comparison study.
Thrombotic Microangiopathies
Intensive plasma exchange increases a disintegrin and metalloprotease with thrombospondin motifs-13 activity and reverses organ dysfunction in children with thrombocytopenia-associated multiple organ failure.
Thrombotic Microangiopathies
Refractory thrombotic thrombocytopenic purpura associated with oral contraceptives and factor V Leiden: a case report.
Thrombotic Microangiopathies
Specific von Willebrand factor-cleaving protease in thrombotic microangiopathies: a study of 111 cases.
Thrombotic Microangiopathies
Variations in the ratio between von Willebrand factor and its cleaving protease during systemic inflammation and association with severity and prognosis of organ failure.
Thrombotic Microangiopathies
Von Willebrand factor--cleaving protease activity in thrombotic microangiopathy after living donor liver transplantation: a case report.
Thrombotic Microangiopathies
von Willebrand factor-cleaving protease (ADAMTS13) activity in normal non-pregnant women, pregnant and post-delivery women.
Thymoma
A mechanistic target of rapamycin complex 1/2 (mTORC1)/V-Akt murine thymoma viral oncogene homolog 1 (AKT1)/cathepsin H axis controls filaggrin expression and processing in skin, a novel mechanism for skin barrier disruption in patients with atopic dermatitis.
Thymoma
A time-course study of MuLV env gene expression in the AKR thymus: qualitative and quantitative analysis of ecotropic and recombinant virus gene products.
Thymoma
Soluble epithin/PRSS14 secreted from cancer cells contains active angiogenic potential.
Thyroid Cancer, Papillary
Elevated Concentrations of SERPINE2/Protease Nexin-1 and Secretory Leukocyte Protease Inhibitor in the Serum of Patients with Papillary Thyroid Cancer.
Thyroid Cancer, Papillary
High-accuracy Detection of Preoperative Thyroid Nodules Using Combination of BRAFV600E Mutation and TMPRSS4 mRNA Level.
Thyroid Cancer, Papillary
microRNA-539 functions as a tumor suppressor in papillary thyroid carcinoma via the transforming growth factor ?1/Smads signaling pathway by targeting secretory leukocyte protease inhibitor.
Thyroid Carcinoma, Anaplastic
Targeting ubiquitin-specific protease 22 suppresses growth and metastasis of anaplastic thyroid carcinoma.
Thyroid Diseases
Association between antiretrovirals and thyroid diseases: a cross-sectional study.
Thyroid Diseases
THE ABSENCE OF THYROID DISEASE IN AN AUSTRALIAN HEPATITIS C COHORT TREATED WITH TRIPLE COMBINATION THERAPY: A PARADIGM SHIFT.
Thyroid Diseases
[Current protease-antibody-based serodiagnostic tools and their use in the diagnosis of autoimmune thyroid diseases]
Thyroid Neoplasms
Differentiated thyroid cancer cell invasion is regulated through epidermal growth factor receptor-dependent activation of matrix metalloproteinase (MMP)-2/gelatinase A.
Thyroid Neoplasms
Expression of TMPRSS4 in non-small cell lung cancer and its modulation by hypoxia.
Thyroid Neoplasms
Interspecies differences in membrane-associated protease activities of thyrocytes and their relevance for thyroid cancer studies.
Thyroid Neoplasms
Iodide-induced thyrotoxicosis in a thyroidectomized patient with metastatic thyroid carcinoma.
Thyroid Neoplasms
Processing of pro-CGRP in a rat medullary thyroid carcinoma cell line transfected with protease inhibitors.
Thyroid Neoplasms
Transmembrane protease serine 4 promotes thyroid cancer proliferation via CREB phosphorylation.
Thyrotoxicosis
Iodide-induced thyrotoxicosis in a thyroidectomized patient with metastatic thyroid carcinoma.
Tick Infestations
Longistatin is an unconventional serine protease and induces protective immunity against tick infestation.
Tics
Proteolysis-a characteristic of tumor-initiating cells in murine metastatic breast cancer.
Tinea
A genetic study of an extracellular elastin-hydrolysing protease in the ringworm fungus Arthroderma benhamiae.
Tinea
Antidermatophytic and Protease-inhibiting Activities of Zerumbone: A Natural Sesquiterpene from the Rhizome of
Tinea
Gene expression profiling of protease and non-protease genes in Trichophyton mentagrophytes isolates from dermatophytosis patients by qRT-PCR analysis.
Tinea
Simultaneous dermatophytosis and keratomycosis caused by Trichophyton interdigitale infection: a case report and literature review.
Tinea Capitis
Polymorphic exocellular protease expression in clinical isolates of Trichophyton tonsurans.
Tinea Capitis
Trichophyton tonsurans exocellular protease expression: correlation with clinical presentation in tinea capitis.
Tonsillitis
SLPI and AnxA2 expression in neoplasm-free palatine tonsils is associated with smoking habit of individuals.
Tonsillitis
[Studies on protease and antiprotease activities in tonsillitis. 1. Fibrinolytic activity in the blood of patients with acute tonsillitis (author's transl)]
Toxoplasmosis
Homologous prime-boost strategy with TgPI-1 improves the immune response and protects highly susceptible mice against chronic Toxoplasma gondii infection.
Toxoplasmosis
Sarcoidosis-related anterior uveitis in a patient with human immunodeficiency virus.
Toxoplasmosis
STAT6 activation by Toxoplasma gondii infection induces the expression of Th2 C-C chemokine ligands and B clade serine protease inhibitors in macrophage.
Toxoplasmosis
Toxoplasma gondii protease inhibitor-1 (TgPI-1) is a novel vaccine candidate against toxoplasmosis.
Toxoplasmosis, Cerebral
Drug-Induced Kidney Stones and Crystalline Nephropathy: Pathophysiology, Prevention and Treatment.
Transfusion-Related Acute Lung Injury
Platelet depletion limits the severity but does not prevent the occurrence of experimental transfusion-related acute lung injury.
Trichinellosis
Characterization of a Trichinella spiralis putative serine protease. Study of its potential as sero-diagnostic tool.
Trichinellosis
Evaluation of recombinant serine protease inhibitor from Trichinella spiralis for immunodiagnosis of swine trichinosis.
Trichinellosis
Identification and characterization of immunodominant linear epitopes on the antigenic region of a serine protease in newborn Trichinella larvae.
Trichinellosis
Identification of surface proteins of Trichinella spiralis muscle larvae using immunoproteomics.
Trichinellosis
Primary assessment of a T. spiralis putative serine protease for early serological detection of experimental trichinellosis.
Trichinellosis
Proteomic Analysis of Trichinella spiralis Adult Worm Excretory-Secretory Proteins Recognized by Sera of Patients with Early Trichinellosis.
Trichinellosis
Screening and characterization of early diagnostic antigens in excretory-secretory proteins from Trichinella spiralis intestinal infective larvae by immunoproteomics.
Trichomonas Infections
Comparison between secretory leukocytic protease inhibitor and reactive nitrogen intermediates levels in cervicovaginal secretions from symptomatic and asymptomatic trichomoniasis Egyptians patients.
Triple Negative Breast Neoplasms
CCAAT-displacement protein/cut homeobox transcription factor (CUX1) represses estrogen receptor-alpha (ER-?) in triple-negative breast cancer cells and can be antagonized by muscadine grape skin extract (MSKE).
Triple Negative Breast Neoplasms
EcTI impairs survival and proliferation pathways in triple-negative breast cancer by modulating cell-glycosaminoglycans and inflammatory cytokines.
Triple Negative Breast Neoplasms
pHLIP(Var7)-P1AP suppresses tumor cell proliferation in MDA-MB-231 triple-negative breast cancer by targeting protease activated receptor 1.
Triple Negative Breast Neoplasms
Secretory leukocyte protease inhibitor (SLPI) as a potential target for inhibiting metastasis of triple-negative breast cancers.
Trypanosomiasis, African
Isolation and characterization of the tsetse thrombin inhibitor: a potent antithrombotic peptide from the saliva of Glossina morsitans morsitans.
Trypanosomiasis, African
Novel compounds to combat trypanosomatid infections: a medicinal chemical perspective.
Trypanosomiasis, African
Optimization Strategy of Novel Peptide-Based Michael Acceptors for the Treatment of Human African Trypanosomiasis.
Tuberculosis
A double transgenic mouse model expressing human pregnane X receptor and cytochrome P450 3A4.
Tuberculosis
A genetic programming-based approach to identify potential inhibitors of serine protease of Mycobacterium tuberculosis.
Tuberculosis
A protein fragment of Rv3194c located on mycobacterial cell surface efficiently prevents adhesion of recombinant Mycobacterium smegmatis, and promises a new anti-adhesive drug.
Tuberculosis
A sensitive and specific ES-31 antigen detection based fluorometric assay for confirmation of Mycobacterium tuberculosis in cell culture.
Tuberculosis
A structurally informed autotransporter platform for efficient heterologous protein secretion and display.
Tuberculosis
Adjunct antibody administration with standard treatment reduces relapse rates in a murine tuberculosis model of necrotic granulomas.
Tuberculosis
Adoption of evidence-informed guidelines in prescribing protease inhibitors for HIV-Tuberculosis co-infected patients on rifampicin and effects on HIV treatment outcomes in Uganda.
Tuberculosis
An allosteric switch regulates Mycobacterium tuberculosis ClpP1P2 protease function as established by cryo-EM and methyl-TROSY NMR.
Tuberculosis
An autotransporter display platform for the development of multivalent recombinant bacterial vector vaccines.
Tuberculosis
Antiretroviral Therapy Outcomes in HIV-Infected Children after Adjusting Protease Inhibitor Dosing during Tuberculosis Treatment.
Tuberculosis
Bioprospecting endophytic fungi from Fusarium genus as sources of bioactive metabolites.
Tuberculosis
Can an optimization/scoring procedure in ligand-protein docking be employed to probe drug-resistant mutations in proteins?
Tuberculosis
Characterization of a novel Mycobacterium tuberculosis serine protease (Rv3194c) activity and pathogenicity.
Tuberculosis
Characterization of a secretory hydrolase from Mycobacterium tuberculosis sheds critical insight into host lipid utilization by M. tuberculosis.
Tuberculosis
Chemiluminescent Protease Probe for Rapid, Sensitive, and Inexpensive Detection of Live Mycobacterium tuberculosis.
Tuberculosis
Cleavage of molybdopterin synthase MoaD-MoaE linear fusion by JAMM/MPN+ domain containing metalloprotease DR0402 from Deinococcus radiodurans.
Tuberculosis
Cleavage specificity of Mycobacterium tuberculosis ClpP1P2 protease and identification of novel peptide substrates and boronate inhibitors with anti-bacterial activity.
Tuberculosis
ClgR regulation of chaperone and protease systems is essential for Mycobacterium tuberculosis parasitism of the macrophage.
Tuberculosis
Clinical update: impact of HIV protease inhibitors on the treatment of HIV-infected tuberculosis patients with rifampin.
Tuberculosis
Cloning, expression, and immunological evaluation of two putative secreted serine protease antigens of Mycobacterium tuberculosis.
Tuberculosis
Correction: The Mycobacterium tuberculosis ClpP1P2 Protease Interacts Asymmetrically with Its ATPase Partners ClpX and ClpC1.
Tuberculosis
Detection of free and immune-complexed serine protease and its antibody in TB patients with and without HIV co-infection.
Tuberculosis
Early and Late Virologic Failure After Virologic Suppression in HIV-Infected Asian Children and Adolescents.
Tuberculosis
Effect of HIV protease inhibitors and Orlistat on mycobacterial ES-31 serine protease, a potential drug target in Mycobacterium tuberculosis.
Tuberculosis
Elisa protocol for rapid screening of potential anti-tubercular drugs based on antigenic reactivity of mycobacterial ES-31 serine protease - a drug target supported by axenic culture of Mycobacterium tuberculosis H37 Ra strain in the presence of inhibitor.
Tuberculosis
Evaluation of apoptotic protease-activating Factor-1 and cluster of Differentiation-4+ T-Cell counts in patients-infected with mycobacterium tuberculosis in Bauchi, Nigeria.
Tuberculosis
Expression of recombinant protease MarP from Mycobacterium tuberculosis in Pichia pastoris and its effect on human monocytes.
Tuberculosis
Factors Associated with the Development of Drug Resistance Mutations in HIV-1 Infected Children Failing Protease Inhibitor-Based Antiretroviral Therapy in South Africa.
Tuberculosis
Follow-up to management strategies for candidates for protease inhibitors and requiring treatment for Mycobacterium tuberculosis.
Tuberculosis
From the Centers for Disease Control and Prevention. Clinical update: impact of HIV protease inhibitors on the treatment of HIV-infected tuberculosis patients with rifampin.
Tuberculosis
Homomultimeric protease in the hyperthermophilic bacterium Thermotoga maritima has structural and amino acid sequence homology to bacteriocins in mesophilic bacteria.
Tuberculosis
Host defense responses to infection by Mycobacterium tuberculosis. Induction of IRF-1 and a serine protease inhibitor.
Tuberculosis
IgG subclass antibody response to mycobacterial serine protease at different stages of pulmonary tuberculosis.
Tuberculosis
In vivo-activated mononuclear phagocytes and protective immunity to chlamydiae in mice.
Tuberculosis
Induction of macrophage-derived SLPI by Mycobacterium tuberculosis depends on TLR2 but not MyD88.
Tuberculosis
Induction of serine protease inhibitor 9 by Mycobacterium tuberculosis inhibits apoptosis and promotes survival of infected macrophages.
Tuberculosis
Inhibition of Mycobacterium tuberculosis secretory serine protease blocks bacterial multiplication both in axenic culture and in human macrophages.
Tuberculosis
Insights into the inter-ring plasticity of caseinolytic proteases from the X-ray structure of Mycobacterium tuberculosis ClpP1.
Tuberculosis
Management strategies for candidates for protease inhibitors and requiring treatment for Mycobacterium tuberculosis. TB/HIV Advisory Committee.
Tuberculosis
Mycobacterial Caseinolytic Protease Gene Regulator ClgR Is a Substrate of Caseinolytic Protease.
Tuberculosis
Mycobacterial ES-31 serine protease--a biomarker for mycobacterium tuberculosis--a preliminary report.
Tuberculosis
Mycobacterial excretory secretory-31 protein with serine protease and lipase activities: An immunogen and drug target against tuberculosis infection.
Tuberculosis
Mycobacterium tuberculosis MycP1 protease plays a dual role in regulation of ESX-1 secretion and virulence.
Tuberculosis
Mycobacterium tuberculosis proteasomal ATPase Mpa has a ?-grasp domain that hinders docking with the proteasome core protease.
Tuberculosis
Mycobacterium tuberculosis Serine Protease Rv3668c Can Manipulate the Host-Pathogen Interaction via Erk-NF-?B Axis-Mediated Cytokine Differential Expression.
Tuberculosis
MycoProtease-DB: Useful resource for Mycobacterium tuberculosis complex and nontuberculous mycobacterial proteases.
Tuberculosis
Mycosin-1, a subtilisin-like serine protease of Mycobacterium tuberculosis, is cell wall-associated and expressed during infection of macrophages.
Tuberculosis
Mycosins Are Required for the Stabilization of the ESX-1 and ESX-5 Type VII Secretion Membrane Complexes.
Tuberculosis
Novel Mycosin Protease MycP1 Inhibitors Identified by Virtual Screening and 4D Fingerprints.
Tuberculosis
Once-daily regimen of saquinavir, ritonavir, didanosine, and lamivudine in HIV-infected patients with standard tuberculosis therapy (TBQD Study).
Tuberculosis
Pentapeptide boronic acid inhibitors of Mycobacterium tuberculosis MycP1 protease.
Tuberculosis
PepD participates in the mycobacterial stress response mediated through MprAB and SigE.
Tuberculosis
Pharmacokinetic interaction between rifampicin and the once-daily combination of saquinavir and low-dose ritonavir in HIV-infected patients with tuberculosis.
Tuberculosis
Pharmacokinetic interaction between rifampin and the combination of indinavir and low-dose ritonavir in HIV-infected patients.
Tuberculosis
Protease inhibitor-containing antiretroviral treatment and tuberculosis: can rifabutin fill the breach?
Tuberculosis
Purification and characterization of a 31 kDa mycobacterial excretory-secretory antigenic protein with a diagnostic potential in pulmonary tuberculosis.
Tuberculosis
Randomised Pharmacokinetic Trial of Rifabutin with Lopinavir/Ritonavir-Antiretroviral Therapy in Patients with HIV-Associated Tuberculosis in Vietnam.
Tuberculosis
Randomized pharmacokinetic evaluation of different rifabutin doses in African HIV- infected tuberculosis patients on lopinavir/ritonavir-based antiretroviral therapy.
Tuberculosis
Rhomboid homologs in Mycobacteria: insights from Phylogeny and Genomic analysis.
Tuberculosis
Rifamycin-resistant Mycobacterium tuberculosis in the highly active antiretroviral therapy era: a report of 3 relapses with acquired rifampin resistance following alternate-day rifabutin and boosted protease inhibitor therapy.
Tuberculosis
Risk factors for tuberculosis after highly active antiretroviral treatment (HAART) initiation among HIV patients: A systematic review.
Tuberculosis
Role of protease inhibitor 9 in survival and replication of Mycobacterium tuberculosis in mononuclear phagocytes from HIV-1-infected patients.
Tuberculosis
Safety and Pharmacokinetics of Double-Dose Lopinavir/Ritonavir + Rifampin Versus Lopinavir/Ritonavir + Daily Rifabutin for Treatment of Human Immunodeficiency Virus-Tuberculosis Coinfection.
Tuberculosis
Sarcoidosis-related anterior uveitis in a patient with human immunodeficiency virus.
Tuberculosis
Serine protease activity contributes to control of Mycobacterium tuberculosis in hypoxic lung granulomas in mice.
Tuberculosis
Site-2 protease substrate specificity and coupling in trans by a PDZ-substrate adapter protein.
Tuberculosis
Species variation in ATP-dependent protein degradation: protease profiles differ between mycobacteria and protease functions differ between Mycobacterium smegmatis and Escherichia coli.
Tuberculosis
Structural basis for the in vitro known acyl-depsipeptide 2 (ADEP2) inhibition to Clp 2 protease from Mycobacterium tuberculosis.
Tuberculosis
Structural insight into serine protease Rv3671c that Protects M. tuberculosis from oxidative and acidic stress.
Tuberculosis
Structure Determination of Mycobacterium tuberculosis Serine Protease Hip1 (Rv2224c).
Tuberculosis
Substrate specificity of MarP, a periplasmic protease required for resistance to acid and oxidative stress in Mycobacterium tuberculosis.
Tuberculosis
Successful treatment of spleen tuberculosis in a patient with human immunodeficiency virus infection.
Tuberculosis
Target-Based Screen Against a Periplasmic Serine Protease That Regulates Intrabacterial pH Homeostasis in Mycobacterium tuberculosis.
Tuberculosis
Targeting Multidrug Resistant Mycobacterium tuberculosis HtrA2 with Identical Chemical Entities of Fluoroquinolones.
Tuberculosis
The complete genome sequence of the Streptomyces temperate phage straight phiC31: evolutionary relationships to other viruses.
Tuberculosis
The crystal structure of an essential high-temperature requirement protein HtrA1 (Rv1223) from Mycobacterium tuberculosis reveals its unique features.
Tuberculosis
The down-regulation of cathepsin G in THP-1 monocytes after infection with Mycobacterium tuberculosis is associated with increased intracellular survival of bacilli.
Tuberculosis
The endothelin system has a significant role in the pathogenesis and progression of Mycobacterium tuberculosis infection.
Tuberculosis
The HtrA-Like Serine Protease PepD Interacts with and Modulates the Mycobacterium tuberculosis 35-kDa Antigen Outer Envelope Protein.
Tuberculosis
The Impact of IFN-? Receptor on SLPI Expression in Active Tuberculosis: Association with Disease Severity.
Tuberculosis
The Mycobacterium tuberculosis ClpP1P2 Protease Interacts Asymmetrically with Its ATPase Partners ClpX and ClpC1.
Tuberculosis
The Mycobacterium tuberculosis proteasome: more than just a barrel-shaped protease.
Tuberculosis
The putative propeptide of MycP1 in mycobacterial type VII secretion system does not inhibit protease activity but improves protein stability.
Tuberculosis
The unfoldase ClpC1 of Mycobacterium tuberculosis regulates the expression of a distinct subset of proteins having intrinsically disordered termini.
Tuberculosis
The utility of nucleos(t)ide-only regimens in the treatment of Mycobacterium tuberculosis-HIV-1 coinfection.
Tuberculosis
Tuberculosis treatment practices in the era of protease inhibitors: a provider survey.
Tuberculosis
Updated guidelines for the use of rifabutin or rifampin for the treatment and prevention of tuberculosis among HIV-infected patients taking protease inhibitors or nonnucleoside reverse transcriptase inhibitors.
Tuberculosis
Use of rifabutin with protease inhibitors for human immunodeficiency virus-infected patients with tuberculosis.
Tuberculosis
[Changes in serum protease and cytokine in patients with silicosis, tuberculosis, and lung cancer].
Tuberculosis
[Changes in the activity of protease inhibitors during thoracic tuberculosis surgery under combined anesthesia]
Tuberculosis
[Immunological and nonspecific reactivity in patients with infiltrative pulmonary tuberculosis associated with chronic nonspecific lung diseases]
Tuberculosis
[Studies on the protease activity of brucellae, M. tuberculosis and Bac. anthracis under the influence of sound vibrations, chemical and bactericidal agents]
Tuberculosis, Osteoarticular
[Character of changes in protease inhibitory capacity of blood in experimental osteoarticular tuberculosis]
Tuberculosis, Pulmonary
IgG subclass antibody response to mycobacterial serine protease at different stages of pulmonary tuberculosis.
Tuberculosis, Pulmonary
[Characteristics of the biochemical blood indices in patients with pulmonary tuberculosis complicated with chronic bronchitis]
Tuberculosis, Pulmonary
[Effectiveness of complex treatment in combination with short-wave therapy and protease inhibitors in first detected patients with pulmonary tuberculosis]
Tuberculosis, Pulmonary
[Effects of natural protease inhibitors on hemostasis and serum proteolysis blockers in patients with pulmonary tuberculosis]
Tuberculosis, Pulmonary
[Evolution of AIDS survival in Spain: effect of the inclusion of pulmonary tuberculosis for case definition in the protease inhibitors era]
Tularemia
Matrix metalloproteinase 9 activity enhances host susceptibility to pulmonary infection with type A and B strains of Francisella tularensis.
Typhus, Epidemic Louse-Borne
A Typhus Group-Specific Protease Defies Reductive Evolution In Rickettsiae.
Unverricht-Lundborg Syndrome
A pathogenetic hypothesis of Unverricht-Lundborg disease onset and progression.
Ureaplasma Infections
Ureaplasma Infection Mediated Release of Matrix Metalloproteinase-9 and PGP - a Novel Mechanism of Preterm Rupture of Membranes and Chorioamnionitis.
Uremia
Changes in health and disease of the metalloprotease that cleaves von Willebrand factor.
Ureteral Obstruction
A serine protease inhibitor attenuates aldosterone-induced kidney injuries via the suppression of plasmin activity.
Ureteral Obstruction
Role of protease activated receptor-2 expression in renal interstitial fibrosis model in mice.
Urinary Bladder Neoplasms
Abrogation of the invasion of human bladder tumor cells by using protease inhibitor(s).
Urinary Bladder Neoplasms
Assess the expression of ubiquitin specific protease USP2a for bladder cancer diagnosis.
Urinary Bladder Neoplasms
Effect of leupeptin, a protease inhibitor, on induction of bladder tumors in rats by n-butyl-n-(4-hydroxybutyl)nitrosamine.
Urinary Bladder Neoplasms
Effect of protease inhibitors in mice treated with the hepatocarcinogen, hexachlorocyclohexane (alpha-isomer) and the bladder carcinogen, N-butyl-N-(4-hydroxybutyl)nitrosamine.
Urinary Bladder Neoplasms
Expression of protease activating receptor-2 (PAR-2) is positively correlated with the recurrence of non-muscle invasive bladder cancer: an immunohistochemical analysis.
Urinary Bladder Neoplasms
Further studies on the effect of leupeptin, a protease inhibitor, on induction of bladder tumors in rats by N-butyl-N-(4-hydroxybutyl)nitrosamine.
Urinary Bladder Neoplasms
Levels of plasma cysteine-proteinase activity in bladder cancer patients.
Urinary Bladder Neoplasms
Mechanisms of human bladder tumor invasion: role of protease cathepsin B.
Urinary Bladder Neoplasms
Partial characterization of a cell motility factor from human urine.
Urinary Bladder Neoplasms
Targeting plasminogen activator inhibitor-1 inhibits angiogenesis and tumor growth in a human cancer xenograft model.
Urinary Bladder Neoplasms
The ubiquitin-specific protease USP2a enhances tumor progression by targeting cyclin A1 in bladder cancer.
Urinary Calculi
Endourological management of a rare radiopaque ritonavir-composed urinary calculus.
Urinary Incontinence
Prevalence and Predictors of Urinary Incontinence at 1 Year Postpartum.
Urinary Tract Infections
Identification of protease and rpoN-associated genes of uropathogenic Proteus mirabilis by negative selection in a mouse model of ascending urinary tract infection.
Urinary Tract Infections
Multiple virulence factors regulated by quorum sensing may help in establishment and colonisation of urinary tract by Pseudomonas aeruginosa during experimental urinary tract infection.
Urolithiasis
Renal effects of non-tenofovir antiretroviral therapy in patients living with HIV.
Urolithiasis
The urological management of the patient with acquired immunodeficiency syndrome.
Urolithiasis
[Urinary lithiasis secondary to medication in HIV+ patients receiving Indinavir]
Urticaria
Beneficial effects of danazol on symptoms and laboratory changes in cholinergic urticaria.
Urticaria
Chronic urticaria: A disease at a crossroad between autoimmunity and coagulation.
Urticaria
Occupational allergic contact urticaria and rhinoconjunctivitis from a detergent protease.
Urticaria
Serum alpha 1-protease inhibitor levels in patients with chronic idiopathic urticaria.
Uterine Cervical Neoplasms
Aberrant DNA methylation of apoptotic signaling genes in patients responsive and nonresponsive to therapy for cervical carcinoma.
Uterine Cervical Neoplasms
Alpha 1-antitrypsin: a possible tool for diagnosis of cervical cancer.
Uterine Cervical Neoplasms
Angiogenesis in cervical cancer is mediated by HeLa metabolites through endothelial cell tissue kallikrein.
Uterine Cervical Neoplasms
Bioprospecting endophytic fungi from Fusarium genus as sources of bioactive metabolites.
Uterine Cervical Neoplasms
Calcium store sensor stromal-interaction molecule 1-dependent signaling plays an important role in cervical cancer growth, migration, and angiogenesis.
Uterine Cervical Neoplasms
Effects of HIV protease, nucleoside/non-nucleoside reverse transcriptase inhibitors on Bax, Bcl-2 and apoptosis in two cervical cell lines.
Uterine Cervical Neoplasms
Gossypol Reduces Metastasis and Epithelial-Mesenchymal Transition by Targeting Protease in Human Cervical Cancer.
Uterine Cervical Neoplasms
Inactivation of the cystatin E/M tumor suppressor gene in cervical cancer.
Uterine Cervical Neoplasms
Kallikrein-8 Proteolytically Processes Human Papillomaviruses in the Extracellular Space To Facilitate Entry into Host Cells.
Uterine Cervical Neoplasms
Lack of apoptotic protease activating factor-1 expression and resistance to hypoxia-induced apoptosis in cervical cancer.
Uterine Cervical Neoplasms
Mechanisms of Growth Inhibition in Human Papillomavirus Positive and Negative Cervical Cancer Cells by the Chloromethyl Ketone Protease Inhibitor, AAPFCMK.
Uterine Cervical Neoplasms
p38 Kinase is Crucial for Osteopontin-induced Furin Expression that Supports Cervical Cancer Progression.
Uterine Cervical Neoplasms
Phloretin suppresses metastasis by targeting protease and inhibits cancer stemness and angiogenesis in human cervical cancer cells.
Uterine Cervical Neoplasms
Proteomic analysis of cancer tissues: shedding light on carcinogenesis and possible biomarkers.
Uterine Cervical Neoplasms
Role of protease activated receptor-2 in lymph node metastasis of uterine cervical cancers.
Uterine Cervical Neoplasms
Serine protease inhibition and mitochondrial dysfunction associated with cisplatin resistance in human tumor cell lines: targets for therapy.
Uterine Cervical Neoplasms
The new-generation proteasome inhibitor oprozomib increases the sensitivity of cervical cancer cells to cisplatin-induced apoptosis.
Uterine Cervical Neoplasms
The novel serine protease tumor-associated differentially expressed gene-14 (KLK8/Neuropsin/Ovasin) is highly overexpressed in cervical cancer.
Uterine Cervical Neoplasms
The serine protease stratum corneum chymotryptic enzyme (kallikrein 7) is highly overexpressed in squamous cervical cancer cells.
Uterine Cervical Neoplasms
Ubiquitin-specific protease 22: a novel molecular biomarker in cervical cancer prognosis and therapeutics.
Uterine Cervical Neoplasms
[A clinical value of peripheral lymphocytes percentage and the levels of protease inhibitors in sera of patients with cervical cancer]
Uterine Neoplasms
A disintegrin and metalloproteinase 9 is involved in ectodomain shedding of receptor-binding cancer antigen expressed on SiSo cells.
Uveitis
A novel de novo CAPN5 mutation in a patient with inflammatory vitreoretinopathy, hearing loss, and developmental delay.
Uveitis
Anterior uveitis associated with intravenous cidofovir use in patients with cytomegalovirus retinitis.
Uveitis
Expression of serine protease inhibitor 3 in ocular tissues in endotoxin-induced uveitis in rat.
Uveitis
Functional validation of a human CAPN5 exome variant by lentiviral transduction into mouse retina.
Uveitis
Sarcoidosis-related anterior uveitis in a patient with human immunodeficiency virus.
Uveitis
Toxic uveitis caused by pharmacodynamic interactions of Rifabutin and protease inhibitors: a case report.
Uveitis
Uveitis following administration of the protease inhibitor indinavir to a patient with AIDS.
Uveitis
[Acute hypopyon uveitis with rifabutin therapy of systemic Mycobacterium avium complex (MAC) infection in AIDS]
Uveitis, Anterior
Alpha 1 antitrypsin serum levels and phenotypes in patients with retinal vasculitis.
Vaccinia
Activation of an influenza virus A/turkey/Oregon/71 HA insertion variant by the subtilisin-like endoprotease furin.
Vaccinia
Amino acid substitutions in the poliovirus maturation cleavage site affect assembly and result in accumulation of provirions.
Vaccinia
Ceramides induce a form of apoptosis in human acute lymphoblastic leukemia cells that is inhibited by Bcl-2, but not by CrmA.
Vaccinia
Comparison of substrate specificities against the fusion glycoprotein of virulent Newcastle disease virus between a chick embryo fibroblast processing protease and mammalian subtilisin-like proteases.
Vaccinia
Current approaches to the development of vaccines effective against parainfluenza and respiratory syncytial viruses.
Vaccinia
Deletion analysis of dengue virus type 4 nonstructural protein NS2B: identification of a domain required for NS2B-NS3 protease activity.
Vaccinia
Expression of functional protease and subviral particles by vaccinia virus containing equine infectious anaemia virus gag and 5' pol genes.
Vaccinia
High yield synthesis and characterization of phosphorylated recombinant human procathepsin D expressed in mammalian cells.
Vaccinia
Human immunodeficiency virus-like, nonreplicating, gag-env particles assemble in a recombinant vaccinia virus expression system.
Vaccinia
Identification of HTLV-I gag protease and its sequential processing of the gag gene product.
Vaccinia
Increased antibody responses to human papillomavirus type 16 L1 protein expressed by recombinant vaccinia virus lacking serine protease inhibitor genes.
Vaccinia
Intracellular expression and processing of foot-and-mouth disease virus capsid precursors using vaccinia virus vectors: influence of the L protease.
Vaccinia
Isolation and characterization of neutralizing monoclonal antibodies to vaccinia virus.
Vaccinia
Maturation of human immunodeficiency virus particles assembled from the gag precursor protein requires in situ processing by gag-pol protease.
Vaccinia
Maturation of the trans-Golgi network protease furin: compartmentalization of propeptide removal, substrate cleavage, and COOH-terminal truncation.
Vaccinia
Non-essential genes in the vaccinia virus HindIII K fragment: a gene related to serine protease inhibitors and a gene related to the 37K vaccinia virus major envelope antigen.
Vaccinia
Nucleotide sequence of XhoI O fragment of ectromelia virus DNA reveals significant differences from vaccinia virus.
Vaccinia
Poliovirus capsid proteins derived from P1 precursors with glutamine-valine cleavage sites have defects in assembly and RNA encapsidation.
Vaccinia
Processing of gag precursor polyprotein of human T-cell leukemia virus type I by virus-encoded protease.
Vaccinia
Recognition of novel viral sequences that associate with the dynein light chain LC8 identified through a pepscan technique.
Vaccinia
SPI-1 is a missing host-range factor required for replication of the attenuated modified vaccinia Ankara (MVA) vaccine vector in human cells.
Vaccinia
Stretch-induced hypertrophic growth of cardiocytes and processing of brain-type natriuretic peptide are controlled by proprotein-processing endoprotease furin.
Vaccinia
The vaccinia virus A56 protein: a multifunctional transmembrane glycoprotein that anchors two secreted viral proteins.
Vaccinia
The vaccinia virus K2L gene encodes a serine protease inhibitor which inhibits cell-cell fusion.
Vaccinia
Triad of human cellular proteins, IRF2, FAM111A, and RFC3, restrict replication of orthopoxvirus SPI-1 host-range mutants.
Vaccinia
Vaccinia virus encodes two proteins that are structurally related to members of the plasma serine protease inhibitor superfamily.
Vaginitis
Evaluation of the Antimicrobial Activity of an Extract of Lactobacillus casei-Infected Hermetia illucens Larvae Produced Using an Automatic Injection System.
Vaginitis
Secretory Aspartyl Proteinases Cause Vaginitis and Can Mediate Vaginitis Caused by Candida albicans in Mice.
Vaginosis, Bacterial
Effects of pregnancy and bacterial vaginosis on proinflammatory cytokine and secretory leukocyte protease inhibitor concentrations in vaginal secretions.
Vaginosis, Bacterial
Hydrogen Peroxide-Producing Lactobacilli Are Associated With Lower Levels of Vaginal Interleukin-1?, Independent of Bacterial Vaginosis.
Vaginosis, Bacterial
Protease inhibitor effects on prevalence of bacterial vaginosis and human papillomavirus-related lesions.
Varicose Ulcer
Lower levels of PAI-2 may contribute to impaired healing in venous ulcers - a preliminary study.
Varicose Ulcer
Multiplexed analysis of matrix metalloproteinases in leg ulcer tissue of patients with chronic venous insufficiency before and after compression therapy.
Varicose Ulcer
Up-regulation of elastase in acute wounds of healthy aged humans and chronic venous leg ulcers are associated with matrix degradation.
Varicose Veins
Portal vein thrombosis in a patient with HIV treated with a protease inhibitor-containing regimen.
Vascular Calcification
Pathophysiological Implication of Fetuin-A Glycoprotein in the Development of Metabolic Disorders: A Concise Review.
Vascular Calcification
Serine Protease Activation Essential for Endothelial-Mesenchymal Transition in Vascular Calcification.
Vascular Calcification
The role of fetuin-a in cardiac functions and metabolism in peritoneal dialysis patients.
Vascular Diseases
Detection of Cancer-Specific Proteases Using Magnetic Relaxation of Peptide-Conjugated Nanoparticles in Biological Environment.
Vascular Diseases
Endothelial cell apoptosis is induced by fetal plasma from pregnancy with umbilical placental vascular disease.
Vascular Diseases
In vitro inhibition of human MMP-2 collagenolytic and gelatinolytic activity by neutralizing monoclonal antibodies.
Vascular Diseases
Phagocyte enzymes in bronchoalveolar lavage from patients with pulmonary sarcoidosis and collagen vascular disorders.
Vascular Diseases
Plasma Selenium Concentrations Are Sufficient and Associated with Protease Inhibitor Use in Treated HIV-Infected Adults.
Vascular Diseases
Prognostic value of plasma von Willebrand factor and its cleaving protease ADAMTS13 in patients with atrial fibrillation.
Vascular Diseases
Subclinical cardiovascular disease in patients starting contemporary protease inhibitors.
Vascular Diseases
Transgenic chickens expressing human urokinase-type plasminogen activator.
Vascular Diseases
Vaspin protects against LPS?induced ARDS by inhibiting inflammation, apoptosis and reactive oxygen species generation in pulmonary endothelial cells via the Akt/GSK?3? pathway.
Vascular System Injuries
A novel biologic activity of thrombin: stimulation of monocyte chemotactic protein production.
Vascular System Injuries
A zymogen-like factor Xa variant corrects the coagulation defect in hemophilia.
Vascular System Injuries
Ablation of MEK kinase 1 suppresses intimal hyperplasia by impairing smooth muscle cell migration and urokinase plasminogen activator expression in a mouse blood-flow cessation model.
Vascular System Injuries
Activated protein C attenuates endotoxin-induced pulmonary vascular injury by inhibiting activated leukocytes in rats.
Vascular System Injuries
Binding of human plasminogen and urokinase-type plasminogen activator to the Lyme disease spirochete, Borrelia burgdorferi.
Vascular System Injuries
Bolus injections of novel thrombogenic site-targeted fusion proteins comprising annexin-V and Kunitz protease inhibitors attenuate intimal hyperplasia after balloon angioplasty.
Vascular System Injuries
Characteristics of gabexate mesilate-induced cell injury in porcine aorta endothelial cells.
Vascular System Injuries
Effect of nafamostat on N-methyl-D-aspartate-induced retinal neuronal and capillary degeneration in rats.
Vascular System Injuries
Effector cell protease receptor-1, a platelet activation-dependent membrane protein, regulates prothrombinase-catalyzed thrombin generation.
Vascular System Injuries
Gabexate mesilate, a synthetic anticoagulant, inhibits the expression of endothelial leukocyte adhesion molecules in vitro.
Vascular System Injuries
Gabexate mesilate, a synthetic protease inhibitor, attenuates endotoxin-induced pulmonary vascular injury by inhibiting tumor necrosis factor production by monocytes.
Vascular System Injuries
IGF-binding protein-4 expression and IGF-binding protein-4 protease activity are regulated coordinately in smooth muscle during postnatal development and after vascular injury.
Vascular System Injuries
Increased expression of protease activated receptor-2 (PAR-2) in balloon-injured rat carotid artery.
Vascular System Injuries
Induction of KDR expression in bovine arterial endothelial cells by thrombin: involvement of nitric oxide.
Vascular System Injuries
Intimal hyperplasia following vascular injury is not inhibited by an antisense thrombin receptor oligodeoxynucleotide.
Vascular System Injuries
Intravascular release of intact cellular fibronectin during oxidant-induced injury of the in vitro perfused rabbit lung.
Vascular System Injuries
Kinetics of thrombin receptor cleavage on intact cells. Relation to signaling.
Vascular System Injuries
Lung vascular injury with protease infusion. Relationship to plasma fibronectin.
Vascular System Injuries
New aspects of integrin-mediated leukocyte adhesion in inflammation: regulation by haemostatic factors and bacterial products.
Vascular System Injuries
Prevention of chronic renal allograft rejection by SERP-1 protein.
Vascular System Injuries
Protease-activated receptor 3 is a second thrombin receptor in humans.
Vascular System Injuries
Protective effects of amino acids against gabexate mesilate-induced cell injury in porcine aorta endothelial cells.
Vascular System Injuries
Protective role of kallistatin in renal fibrosis via modulation of Wnt/?-catenin signaling.
Vascular System Injuries
Pulmonary vascular injury in pancreatitis: evidence for a major role played by pancreatic elastase.
Vascular System Injuries
Role of the thrombin receptor in development and evidence for a second receptor.
Vascular System Injuries
Second Annual Mario S. Verani, MD, Memorial Lecture: Nuclear cardiology, the next 10 years.
Vascular System Injuries
Serine and metalloprotease signaling through PAR1 in arterial thrombosis and vascular injury.
Vascular System Injuries
Structural transitions during prothrombin activation: On the importance of fragment 2.
Vascular System Injuries
The primary fibrin polymerization pocket: three-dimensional structure of a 30-kDa C-terminal gamma chain fragment complexed with the peptide Gly-Pro-Arg-Pro.
Vascular System Injuries
The tertiary structure and domain organization of coagulation factor VIII.
Vascular System Injuries
Thrombin and protease-activated receptors (PARs) in atherothrombosis.
Vascular System Injuries
Thrombin induces angiogenesis and vascular endothelial growth factor expression in human endothelial cells: possible relevance to HIF-1alpha.
Vascular System Injuries
Thrombin receptor expression in normal and atherosclerotic human arteries.
Vascular System Injuries
Thrombin regulates expression of monocyte chemoattractant protein-1 in vascular smooth muscle cells.
Vascular System Injuries
Thrombin-induced CCAAT/enhancer-binding protein ? activation and IL-8/CXCL8 expression via MEKK1, ERK, and p90 ribosomal S6 kinase 1 in lung epithelial cells.
Vascular System Injuries
Zinc (II) selectively enhances the inhibition of coagulation factor XIa by protease nexin-2/amyloid beta-protein precursor.
Vasculitis
Detection of autoantibodies against myeloid lysosomal enzymes: a useful adjunct to classification of patients with biopsy-proven necrotizing arteritis.
Vasculitis
Distinct differences in autoantigen specificity of anti-neutrophil cytoplasm antibodies in systemic vasculitides and other inflammatory diseases.
Vasculitis
Increased monocyte transcription of the proteinase 3 gene in small vessel vasculitis.
Vasculitis
Lack of association of alpha-1 antichymotrypsin gene polymorphism with PR3-ANCA and MPO-ANCA associated vasculitis.
Vasculitis
Matrix Metalloprotease-9 (MMP-9)-Producing Monocytes Enable T Cells to Invade the Vessel Wall and Cause Vasculitis.
Vasculitis
Predominance of IgG1 and IgG4 subclasses of anti-neutrophil cytoplasmic autoantibodies (ANCA) in patients with Wegener's granulomatosis and clinically related disorders.
Vasculitis
Treatment of hepatitis C virus infection in patients with mixed cryoglobulinemic syndrome and cryoglobulinemic glomerulonephritis.
Vasospasm, Intracranial
Attenuation of vasospasm and hemoglobin-induced constriction in the rabbit basilar artery by a novel protease inhibitor.
Vasospasm, Intracranial
Broad-spectrum and selective serine protease inhibitors prevent expression of platelet-derived growth factor-BB and cerebral vasospasm after subarachnoid hemorrhage: vasospasm caused by cisternal injection of recombinant platelet-derived growth factor-BB.
Vasospasm, Intracranial
Cerebral vasospasm caused by cisternal injection of polystyrene latex beads in rabbits is inhibited by a serine protease inhibitor.
Vasospasm, Intracranial
Combination of serine protease inhibitor FUT-175 and thromboxane synthetase inhibitor OKY-046 decreases cerebral vasospasm in patients with subarachnoid hemorrhage.
Vasospasm, Intracranial
Effects of protease inhibitor and immunosuppressant on cerebral vasospasm after subarachnoid hemorrhage in rabbits.
Vasospasm, Intracranial
Preventive effect of synthetic serine protease inhibitor, FUT-175, on cerebral vasospasm in rabbits.
Vasospasm, Intracranial
Therapeutic trial of cerebral vasospasm with the serine protease inhibitor, FUT-175, administered in the acute stage after subarachnoid hemorrhage.
Vasospasm, Intracranial
Therapeutically Targeting Platelet-Derived Growth Factor-Mediated Signaling Underlying the Pathogenesis of Subarachnoid Hemorrhage-Related Vasospasm.
Venous Thromboembolism
Enhanced Biopharmaceutical Performance of Rivaroxaban through Polymeric Amorphous Solid Dispersion.
Venous Thromboembolism
Human immunodeficiency virus infection and risk of venous thromboembolism.
Venous Thromboembolism
Polymorphisms of the protein Z-dependent protease inhibitor (ZPI) gene and the risk of venous thromboembolism.
Venous Thromboembolism
Polymorphisms of the Z protein protease inhibitor and risk of venous thromboembolism: a meta-analysis.
Venous Thromboembolism
Prospective study of polymorphisms of the protein Z-dependent protease inhibitor and risk of venous thromboembolism.
Venous Thromboembolism
Risk factors for venous thromboembolism in patients with human immunodeficiency virus infection.
Venous Thrombosis
A nonsense polymorphism in the protein Z-dependent protease inhibitor increases the risk for venous thrombosis.
Venous Thrombosis
Dual-reporter high-throughput screen for small-molecule in vivo inhibitors of plasminogen activator inhibitor type-1 yields a clinical lead candidate.
Venous Thrombosis
Intracellular accumulation of antithrombin Morioka (C95R), a novel mutation causing type I antithrombin deficiency.
Venous Thrombosis
Mutation study of antithrombin: the roles of disulfide bonds in intracellular accumulation and formation of russell body-like structures.
Venous Thrombosis
Protease activated receptor 1 gene -506 I?/?D polymorphism in cancer patients with and without venous thrombosis.
Venous Thrombosis
Protein Z and protein Z-dependent protease inhibitor. Determinants of levels and risk of venous thrombosis.
Venous Thrombosis
Protein Z-dependent protease inhibitor W303X mutation in venous thrombosis.
Venous Thrombosis
Single Nucleotide Variant rs2232710 in the Protein Z-Dependent Protease Inhibitor (ZPI, SERPINA10) Gene Is Not Associated with Deep Vein Thrombosis.
Venous Thrombosis
Symptomatic type 1 protein C deficiency caused by a de novo Ser270Leu mutation in the catalytic domain.
Venous Thrombosis
Two missense mutations identified in venous thrombosis patients impair the inhibitory function of the protein Z dependent protease inhibitor.
Venous Thrombosis
Venous thrombo-embolism and raised alpha-1-antitrypsin levels. A possible causal relationship between excessive neutral protease inhibition and defective granulocyte-induced fibrinolysis.
Ventilator-Induced Lung Injury
Preventing loss of mechanosensation by the nuclear membranes of alveolar cells reduces lung injury in mice during mechanical ventilation.
Vesicular Stomatitis
A proline-rich region in the coxsackievirus 3A protein is required for the protein to inhibit endoplasmic reticulum-to-golgi transport.
Vesicular Stomatitis
Newly synthesized G protein of vesicular stomatitis virus is not transported to the cell surface during mitosis.
Vesicular Stomatitis
Permeability properties of the membrane of vesicular stomatitis virions.
Vibrio Infections
Functional Characterization of Vibrio alginolyticus Twin-Arginine Translocation System: Its Roles in Biofilm Formation, Extracellular Protease Activity, and Virulence Towards Fish.
Vibrio Infections
Microbial and histopathological study of the vibriosis caused by Vibrio vulnificus serovar E in eels: the metalloprotease Vvp is not an essential lesional factor.
Vibrio Infections
Pathogenesis studies on Vibrio alginolyticus in the grouper, Epinephelus malabaricus, Bloch et Schneider.
Vibrio Infections
Protection of Atlantic salmon against vibriosis with Vibrio anguillarum protease.
Vibrio Infections
Purification and partial characterisation of a fish lethal extracellular protease from Vibrio pelagius.
Viremia
A preliminary study of ritonavir, an inhibitor of HIV-1 protease, to treat HIV-1 infection.
Viremia
Antiretroviral drug therapy alters the profile of human immunodeficiency virus type 1-specific T-cell responses and shifts the immunodominant cytotoxic T-lymphocyte response from Gag to Pol.
Viremia
ART suppresses plasma HIV-1 RNA to a stable set point predicted by pretherapy viremia.
Viremia
Assessment of FIV-C infection of cats as a function of treatment with the protease inhibitor, TL-3.
Viremia
Clinical evaluation of an in-house reverse transcription-competitive PCR for quantitation of human immunodeficiency virus type 1 RNA in plasma.
Viremia
Continued production of drug-sensitive human immunodeficiency virus type 1 in children on combination antiretroviral therapy who have undetectable viral loads.
Viremia
Correlates of antiviral immune restoration in acute and chronic HIV type 1 infection: sustained viral suppression and normalization of T cell subsets.
Viremia
Detectability of HIV Residual Viremia despite Therapy Is Highly Associated with Treatment with a Protease Inhibitor-Based Combination Antiretroviral Therapy.
Viremia
Drug resistance and viral evolution in plasma and peripheral blood cells during structured treatment interruption (STI) and non-interrupted HAART.
Viremia
Genotypic and phenotypic cross-resistance patterns to lopinavir and amprenavir in protease inhibitor-experienced patients with HIV viremia.
Viremia
Hepatitis C genotype 1 virus with low viral load and rapid virologic response to peginterferon/ribavirin obviates a protease inhibitor.
Viremia
HHV8 and Kaposi's sarcoma: should we really give up protease inhibitors in all HIV-infected patients?
Viremia
HIV Viral Dynamics of Lopinavir/Ritonavir Monotherapy as Second-Line Treatment: A Prospective, Single-Arm Trial.
Viremia
Impact of protease polymorphisms and viral fitness on human immunodeficiency virus (HIV) type 1 viremia in untreated HIV-1 infection.
Viremia
Impact of treatment with human immunodeficiency virus (HIV) protease inhibitors on hepatitis C viremia in patients coinfected with HIV.
Viremia
Incidence and impact of low-level viremia among people living with HIV who received protease inhibitor- or dolutegravir-based antiretroviral therapy.
Viremia
Inflammatory, procoagulant markers and HIV residual viremia in patients receiving protease inhibitor monotherapy or triple drug therapy: a cross-sectional study.
Viremia
Inhibition of murine AIDS by alternate administration of azidothymidine and fludarabine monophosphate.
Viremia
Intermittent episodes of detectable HIV viremia in patients receiving nonnucleoside reverse-transcriptase inhibitor-based or protease inhibitor-based highly active antiretroviral therapy regimens are equivalent in incidence and prognosis.
Viremia
Intermittent viremia during first-line, protease inhibitors-containing therapy: significance and relationship with drug resistance.
Viremia
Low interleukin-10 production is associated with diabetes in HIV-infected patients undergoing antiviral therapy.
Viremia
Maintaining reduced viral fitness and CD4 response in HIV-infected patients with viremia receiving a boosted protease inhibitor.
Viremia
Mutation patterns of the reverse transcriptase and protease genes in human immunodeficiency virus type 1-infected patients undergoing combination therapy: survey of 787 sequences.
Viremia
Persistence and fitness of multidrug-resistant human immunodeficiency virus type 1 acquired in primary infection.
Viremia
Persistence of Human Immunodeficiency Virus-1 Drug Resistance Mutations in Proviral Deoxyribonucleic Acid After Virologic Failure of Efavirenz-Containing Antiretroviral Regimens.
Viremia
Population genetic analysis of the protease locus of human immunodeficiency virus type 1 quasispecies undergoing drug selection, using a denaturing gradient-heteroduplex tracking assay.
Viremia
Prevalence and clinical correlates of HIV viremia ('blips') in patients with previous suppression below the limits of quantification.
Viremia
Protease inhibitor monotherapy is not associated with increased viral replication in lymph nodes.
Viremia
Relapse of Kaposi's Sarcoma and HHV-8 viremia in an HIV-infected patient switching from protease inhibitor to integrase inhibitor-based antiretroviral therapy.
Viremia
Similar Evolution of Cellular HIV-1 DNA Level in Darunavir/Ritonavir Monotherapy versus Triple Therapy in MONOI -ANRS136 Trial over 96 Weeks.
Viremia
Single-cell analysis of HIV-1 transcriptional activity reveals expression of proviruses in expanded clones during ART.
Viremia
Sustained disappearance of hepatitis C viremia in patients receiving protease inhibitor treatment for human immunodeficiency virus infection.
Viremia
Systemic inflammation and residual viraemia in HIV-positive adults on protease inhibitor monotherapy: a cross-sectional study.
Viremia
The interplay of sociodemographic factors on virologic suppression among a U.S. outpatient HIV clinic population.
Viremia
Time to HIV-1 RNA suppression below 5 copies/ml during first-line protease inhibitor-based antiretroviral treatment - any impact of residual viremia on treatment success?
Viremia
Treatment response in acute/early infection versus advanced AIDS: equivalent first and second phases of HIV RNA decline.
Viremia
Viremia and drug resistance among HIV-1 patients on antiretroviral treatment: a cross-sectional study in Soweto, South Africa.
Viremia
Viremia copy-years as a predictive marker of all-cause mortality in HIV-1-infected patients initiating a protease inhibitor-containing antiretroviral treatment.
Viremia
Virological and immunological stability in HIV infected patients undergoing partial-treatment interruption.
Viremia
[Effects of double and triple antiretroviral agents on the HCV viral load in patients coinfected with HIV and HCV]
Viremia
[Lopinavir/ritonavir monotherapy as a simplification strategy in the treatment of HIV-1 infection]
Viremia
[Predictors of the efficiency of short-term interferon-containing therapy using direct-acting antiviral drugs in patients with chronic hepatitis C virus genotype 1].
Virus Diseases
A comparative study of HIV-1 and HTLV-I protease structure and dynamics reveals a conserved residue interaction network.
Virus Diseases
A dual role for Mannan-binding lectin-associated serine protease 2 (MASP-2) in HIV infection.
Virus Diseases
A novel ubiquitin-specific protease is dynamically associated with the PML nuclear domain and binds to a herpesvirus regulatory protein.
Virus Diseases
A phase I/II study of the protease inhibitor ritonavir in children with human immunodeficiency virus infection.
Virus Diseases
A role for MALT1 activity in Kaposi's sarcoma-associated herpes virus latency and growth of primary effusion lymphoma.
Virus Diseases
ABT-450: A Novel Protease Inhibitor for the Treatment of Hepatitis C Virus Infection.
Virus Diseases
ACE2 expression is related to the interferon response in airway epithelial cells but is that functional for SARS-CoV-2 entry?
Virus Diseases
Adhesive capsulitis of shoulder and treatment with protease inhibitors in patients with human immunodeficiency virus infection: report of 8 cases.
Virus Diseases
Alpha-1 Antitrypsin is Markedly Decreased Following Pulmonary F. tularensis Challenge.
Virus Diseases
An Overview of Spike Surface Glycoprotein in Severe Acute Respiratory Syndrome-Coronavirus.
Virus Diseases
Anti-malarial Drugs are Not Created Equal for SARS-CoV-2 Treatment: A Computational Analysis Evidence.
Virus Diseases
Antiviral effects of peginterferon alpha-2b and ribavirin following 24-week monotherapy of telaprevir in Japanese hepatitis C patients.
Virus Diseases
Apparent Resolution of Type 2 Diabetes Mellitus after Initiation of Potent Antiretroviral Therapy in a Man from Africa with HIV Infection.
Virus Diseases
Atazanavir signature I50L resistance substitution accounts for unique phenotype of increased susceptibility to other protease inhibitors in a variety of human immunodeficiency virus type 1 genetic backbones.
Virus Diseases
Avascular necrosis of bone in patients with human immunodeficiency virus infection: report of 6 cases and review of the literature.
Virus Diseases
Bilateral frozen shoulder associated with a three-drug regimen including a protease inhibitor in a patient with human immunodeficiency virus infection to the editor.
Virus Diseases
Boceprevir: a recently approved protease inhibitor for hepatitis C virus infection.
Virus Diseases
Bone metabolism in children with human immunodeficiency virus infection receiving highly active anti-retroviral therapy including a protease inhibitor.
Virus Diseases
C(2)-Symmetric azobenzene-amino acid conjugates and their inhibition of Subtilisin Kexin Isozyme-1.
Virus Diseases
Caspase 3 from rock bream (Oplegnathus fasciatus): genomic characterization and transcriptional profiling upon bacterial and viral inductions.
Virus Diseases
Challenges in modern drug discovery: a case study of boceprevir, an HCV protease inhibitor for the treatment of hepatitis C virus infection.
Virus Diseases
Characterisation of healthy donor-derived T-cell responses specific to telaprevir diastereomers.
Virus Diseases
Characterization of human liver enzymes involved in the biotransformation of boceprevir, a hepatitis C virus protease inhibitor.
Virus Diseases
Characterization of innate responses to influenza virus infection in a novel lung type I epithelial cell model.
Virus Diseases
Characterization of SA-11 rotavirus receptorial structures on human colon carcinoma cell line HT-29.
Virus Diseases
Comparative studies of the capsid precursor polypeptide P1 and the capsid protein VP1 cDNA vectors for DNA vaccination against foot-and-mouth disease virus.
Virus Diseases
Computer simulations of slow progression of human immunodeficiency virus infection and relapse during anti-HIV treatment with reverse transcriptase inhibitors and protease inhibitors.
Virus Diseases
Contribution of the porcine aminopeptidase N (CD13) receptor density to porcine epidemic diarrhea virus infection.
Virus Diseases
COVID-19-related Genes in Sputum Cells in Asthma. Relationship to Demographic Features and Corticosteroids.
Virus Diseases
COVID?19 and SARS?CoV?2 host cell entry mediators: Expression profiling of TMRSS4 in health and disease.
Virus Diseases
Data, Reagents, Assays and Merits of Proteomics for SARS-CoV-2 Research and Testing.
Virus Diseases
Despite poor interferon response in advanced hepatitis C virus infection, models of protease inhibitor treatment predict maximum treatment benefit.
Virus Diseases
Determination of the HCV protease inhibitor telaprevir in plasma and dried blood spot by liquid chromatography tandem mass spectrometry.
Virus Diseases
Deubiquitinase Ubiquitin-Specific Protease 10 Deficiency Regulates Sirt6 signaling and Exacerbates Cardiac Hypertrophy.
Virus Diseases
Diagnosis of silent myocardial ischemia during the staging of HIV-associated lymphoma with FDG PET/CT.
Virus Diseases
Differential bronchial epithelial response regulated by ?Np63: a functional understanding of the epithelial shedding found in asthma.
Virus Diseases
Diketo acids derivatives as integrase inhibitors: the war against the acquired immunodeficiency syndrome.
Virus Diseases
Direct costs of first-generation protease inhibitors for the treatment of genotype 1 chronic hepatitis C viral infection.
Virus Diseases
Direct-Acting Antiviral-Associated Dermatitis During Chronic Hepatitis C Virus Treatment.
Virus Diseases
Dose- and Formulation-Dependent Non-Linear Pharmacokinetic Model of Paritaprevir, a Protease Inhibitor for the Treatment of Hepatitis C Virus Infection: Combined Analysis from 12 Phase I Studies.
Virus Diseases
Effect of a plant polyphenol-rich extract on the lung protease activities of influenza-virus-infected mice.
Virus Diseases
Effect of internal cleavage site mutations in human immunodeficiency virus type 1 capsid protein on its structure and function.
Virus Diseases
Effect of low-dose ritonavir (100 mg twice daily) on the activity of cytochrome P450 2D6 in healthy volunteers.
Virus Diseases
Evidence for pH Dependent Protease Activity in the Adeno-associated Virus Capsid.
Virus Diseases
Expression characterization, genomic structure and function analysis of fish ubiquitin-specific protease 18 (USP18) genes.
Virus Diseases
Expression of a Toxoneuron nigriceps polydnavirus-encoded protein causes apoptosis-like programmed cell death in lepidopteran insect cells.
Virus Diseases
Expression of stress-response proteins upon whitefly-mediated inoculation of Tomato yellow leaf curl virus in susceptible and resistant tomato plants.
Virus Diseases
Factors associated with long-term CD4 cell recovery in HIV-infected patients on successful antiretroviral therapy.
Virus Diseases
Factors related to lipodystrophy and metabolic alterations in patients with human immunodeficiency virus infection receiving highly active antiretroviral therapy.
Virus Diseases
Frequency of urolithiasis in individuals seropositive for human immunodeficiency virus treated with indinavir is higher than previously assumed.
Virus Diseases
Frequency, specificity, and sites of expansion of CD8+ T cells during primary pulmonary influenza virus infection.
Virus Diseases
Functional diversification upon leader protease domain duplication in the Citrus tristeza virus genome: Role of RNA sequences and the encoded proteins.
Virus Diseases
Future treatment options for HCV: double, triple, what is the optimal combination?
Virus Diseases
Gender susceptibility to COVID-19: a review of the putative role of sex hormones and X chromosome.
Virus Diseases
Gynaecomastia associated with combination antiretroviral therapy including protease inhibitors for human immunodeficiency virus infection.
Virus Diseases
Hepatitis B or hepatitis C virus infection is a risk factor for severe hepatic cytolysis after initiation of a protease inhibitor-containing antiretroviral regimen in human immunodeficiency virus-infected patients. The APROCO Study Group.
Virus Diseases
Hepatitis C virus treatment and liver transplantation in the era of new antiviral therapies.
Virus Diseases
Hepatotoxicity development during antiretroviral therapy containing protease inhibitors in patients with HIV: the role of hepatitis B and C virus infection.
Virus Diseases
High Dietary Fat Modulates Neurobehavioural Effect of Lopinavir/ Ritonavir in Mice.
Virus Diseases
High yield expression of catalytically active USP18 using a Trigger Factor fusion system.
Virus Diseases
High-throughput virtual screening lead to discovery of non-peptidic inhibitors of West Nile virus NS3 protease.
Virus Diseases
HIV-associated vascular diseases: structural and functional changes, clinical implications.
Virus Diseases
Homology modeling and virtual screening for antagonists of protease from yellow head virus.
Virus Diseases
Identification of a single nucleotide promoter polymorphism regulating the transcription of ubiquitin specific protease 18 gene related to the resistance to porcine reproductive and respiratory syndrome virus infection.
Virus Diseases
Identification of ectopic anionic trypsin I in rat lungs potentiating pneumotropic virus infectivity and increased enzyme level after virus infection.
Virus Diseases
Impact of treatment with protease inhibitors on aortic stiffness in adult patients with human immunodeficiency virus infection.
Virus Diseases
In Silico Identification of a Potent Arsenic Based Approved Drug Darinaparsin against SARS-CoV-2: Inhibitor of RNA Dependent RNA polymerase (RdRp) and Essential Proteases.
Virus Diseases
In vivo and in vitro primed lymphocytes. Correlation of cytochemically detected BLT-specific lymphoid serine protease with cytotoxic activity.
Virus Diseases
Infection enhancement of influenza A NWS virus in primary murine macrophages by anti-hemagglutinin monoclonal antibody.
Virus Diseases
Infection of XC cells by MLVs and Ebola virus is endosome-dependent but acidification-independent.
Virus Diseases
Influenza HA Subtypes Demonstrate Divergent Phenotypes for Cleavage Activation and pH of Fusion: Implications for Host Range and Adaptation.
Virus Diseases
Influenza virus activating host proteases: Identification, localization and inhibitors as potential therapeutics.
Virus Diseases
Influenza virus-cytokine-protease cycle in the pathogenesis of vascular hyperpermeability in severe influenza.
Virus Diseases
Inhibition of influenza virus infection and hemagglutinin cleavage by the protease inhibitor HAI-2.
Virus Diseases
Inhibition of influenza virus infection in human airway cell cultures by an antisense peptide-conjugated morpholino oligomer targeting the hemagglutinin-activating protease TMPRSS2.
Virus Diseases
Insights to substrate binding and processing by West Nile Virus NS3 protease through combined modeling, protease mutagenesis, and kinetic studies.
Virus Diseases
Interactions between HIV-infected monocytes and the extracellular matrix: HIV-infected monocytes secrete neutral metalloproteases that degrade basement membrane protein matrices.
Virus Diseases
Intramolecular regulation of the sequence-specific mRNA interferase activity of MazF fused to a MazE fragment with a linker cleavable by specific proteases.
Virus Diseases
Isolation and characterization of novel single-chain Fv specific for human granzyme B.
Virus Diseases
Levels of vaginal secretory leukocyte protease inhibitor are decreased in women with lower reproductive tract infections.
Virus Diseases
Lyme disease: the promise of Big Data, companion diagnostics and precision medicine.
Virus Diseases
Mechanistic Aspects of Medicinal Plants and Secondary Metabolites against Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2).
Virus Diseases
MK-5172 : a second-generation protease inhibitor for the treatment of hepatitis C virus infection.
Virus Diseases
Modulation by cell trypsinization of Sendai virus expression in African green monkey kidney cells: first infection and establishment of a carrier state.
Virus Diseases
Molecular characterization of the processing of arenavirus envelope glycoprotein precursors by subtilisin kexin isozyme-1/site-1 protease.
Virus Diseases
Molecular Docking and Virtual Screening based prediction of drugs for COVID-19.
Virus Diseases
Molecular investigation of bovine viral diarrhea virus infection in yaks (Bos gruniens) from Qinghai, China.
Virus Diseases
Molecular modeling studies and comparative analysis on structurally similar HTLV and HIV protease using HIV-PR inhibitors.
Virus Diseases
Monomorphic ventricular tachycardia due to protease inhibitor intoxication by atazanavir.
Virus Diseases
Myxomavirus-derived serpin prolongs survival and reduces inflammation and hemorrhage in an unrelated lethal mouse viral infection.
Virus Diseases
Naturally occurring mutations to HCV protease inhibitors in treatment-naïve patients.
Virus Diseases
No impairment of endothelial function or insulin sensitivity with 4 weeks of the HIV protease inhibitors atazanavir or lopinavir-ritonavir in healthy subjects without HIV infection: a placebo-controlled trial.
Virus Diseases
Novel Analogues of the Chikungunya Virus Protease Inhibitor: Molecular Design, Synthesis, and Biological Evaluation.
Virus Diseases
Novel protease and polymerase inhibitors for the treatment of hepatitis C virus infection.
Virus Diseases
Penetration of the nucleoside analogue abacavir into the genital tract of men infected with human immunodeficiency virus type 1.
Virus Diseases
Pharmacokinetic interactions between two human immunodeficiency virus protease inhibitors, ritonavir and saquinavir.
Virus Diseases
Plants transformed with a cistron of a potato virus Y protease (NIa) are resistant to virus infection.
Virus Diseases
Plasma bile acid concentrations in patients with human immunodeficiency virus infection receiving protease inhibitor therapy: possible implications for hepatotoxicity.
Virus Diseases
Pretransplant and posttransplant treatment of hepatitis C virus infection with protease inhibitors.
Virus Diseases
Pretreatment with protease is a useful experimental strategy for enhancing adenovirus-mediated cancer gene therapy.
Virus Diseases
Prevalence of naturally occurring protease inhibitor resistance-associated variants in hemodialysis and renal transplant patients with hepatitis C virus infection.
Virus Diseases
Processing of a pestivirus protein by a cellular protease specific for light chain 3 of microtubule-associated proteins.
Virus Diseases
Protease inhibitor therapy post-liver transplantation in the treatment of hepatitis C virus infection.
Virus Diseases
Protease inhibitor treatment effect on aortic stiffness in normotensive patients with human immunodeficiency virus infection.
Virus Diseases
Protease inhibitors for the treatment of human immunodeficiency virus infection.
Virus Diseases
Protease inhibitors for treatment of genotype 1 hepatitis C virus infection.
Virus Diseases
Protective Role of a TMPRSS2 Variant on Severe COVID-19 Outcome in Young Males and Elderly Women.
Virus Diseases
Proteolytic events of HIV-1 replication as targets for therapeutic intervention.
Virus Diseases
Proteomics approaches for the identification of protease substrates during virus infection.
Virus Diseases
Recurrent panniculitis in a patient receiving protease inhibitor therapy for human immunodeficiency virus infection.
Virus Diseases
Regulation of expression of 11beta-hydroxysteroid dehydrogenase type 1 in adipose tissue: tissue-specific induction by cytokines.
Virus Diseases
Replication of a low-pathogenic avian influenza virus is enhanced by chicken ubiquitin-specific protease 18.
Virus Diseases
Respiratory protease/antiprotease balance determines susceptibility to viral infection and can be modified by nutritional antioxidants.
Virus Diseases
Ritonavir-induced lipoatrophy and dyslipidaemia is reversed by the anti-inflammatory drug leflunomide in a PPAR-?-dependent manner.
Virus Diseases
Ser624 of the PA subunit of influenza A virus is not essential for viral growth in cells and mice, but required for the maximal viral growth.
Virus Diseases
Serine protease Bm-SP142 was differentially expressed in resistant and susceptible Bombyx mori strains, involving in the defence response to viral infection.
Virus Diseases
Serine protease inhibitor AEBSF reduces dengue virus infection via decreased cholesterol synthesis.
Virus Diseases
Simultaneous assay for protease activities of hepatitis C virus and human immunodeficiency virus based on fluorescence detection.
Virus Diseases
Smurf1 restricts the antiviral function mediated by USP25 through promoting its ubiquitination and degradation.
Virus Diseases
Specific elimination of coxsackievirus B3 infected cells with a protein engineered toxin-antitoxin system.
Virus Diseases
Spontaneous bleeding associated with the use of the protease inhibitor ritonavir in a hemophiliac patient with human immunodeficiency virus infection.
Virus Diseases
Strong Binding of Leupeptin with TMPRSS2 Protease May Be an Alternative to Camostat and Nafamostat for SARS-CoV-2 Repurposed Drug: Evaluation from Molecular Docking and Molecular Dynamics Simulations.
Virus Diseases
Structural and functional parameters of the flaviviral protease: a promising antiviral drug target.
Virus Diseases
Substitution of nevirapine, efavirenz, or abacavir for protease inhibitors in patients with human immunodeficiency virus infection.
Virus Diseases
Substitution of protease inhibitors during treatment of patients with human immunodeficiency virus infection: frequency, mode, reasons and mid-term outcome.
Virus Diseases
Sustained CD4+ T cell response after virologic failure of protease inhibitor-based regimens in patients with human immunodeficiency virus infection.
Virus Diseases
Sustained disappearance of hepatitis C viremia in patients receiving protease inhibitor treatment for human immunodeficiency virus infection.
Virus Diseases
Synergistic inhibition of influenza A virus replication by a plant polyphenol-rich extract and epsilon-aminocaproic acid in vitro and in vivo.
Virus Diseases
Targeting the intestinal TMPRSS2 protease to prevent SARS-CoV-2 entry into enterocytes-prospects and challenges.
Virus Diseases
Telaprevir: a promising protease inhibitor for the treatment of hepatitis C virus infection.
Virus Diseases
The antiretroviral protease inhibitor ritonavir accelerates glutathione export from cultured primary astrocytes.
Virus Diseases
The beta-chemokines MIP-1alpha and RANTES and lipoprotein metabolism in HIV-infected Brazilian patients.
Virus Diseases
The Challenge of Potential Drug-Drug Interactions Among People Living With HIV on Antiretroviral Therapy: A Cross-Sectional Study in Selected Provinces in China.
Virus Diseases
The effect of internal autocleavage on kinetic properties of the human cytomegalovirus protease catalytic domain.
Virus Diseases
The effect of mutant peptide cofactors on adenovirus protease activity and virus infection.
Virus Diseases
The endogenous cellular protease inhibitor SPINT2 controls SARS-CoV-2 viral infection and is associated to disease severity.
Virus Diseases
The hypervariable amino-terminus of p1 protease modulates potyviral replication and host defense responses.
Virus Diseases
The Protease Inhibitor Monotherapy Versus Ongoing Triple Therapy (PIVOT) trial: a randomised controlled trial of a protease inhibitor monotherapy strategy for long-term management of human immunodeficiency virus infection.
Virus Diseases
The serine protease inhibitor camostat inhibits influenza virus replication and cytokine production in primary cultures of human tracheal epithelial cells.
Virus Diseases
The transmembrane serine protease hepsin suppresses type I interferon induction by cleaving STING.
Virus Diseases
The Type I Interferon-IRF7 Axis Mediates Transcriptional Expression of Usp25 Gene.
Virus Diseases
Toward the physiological basis for increased Agrotis ipsilon multiple nucleopolyhedrovirus infection following feeding of Agrotis ipsilon larvae on transgenic corn expressing Cry1Fa2.
Virus Diseases
Transmembrane serine protease TMPRSS2 activates hepatitis C virus infection.
Virus Diseases
Treatment of facial fat atrophy related to treatment with protease inhibitors by autologous fat injection in patients with human immunodeficiency virus infection.
Virus Diseases
Treatment of human immunodeficiency virus infection with hydroxyurea, didanosine, and a protease inhibitor before seroconversion is associated with normalized immune parameters and limited viral reservoir.
Virus Diseases
Trends in hepatitis C virus infection therapy: protease inhibitors a step forward in the era of direct acting antivirals.
Virus Diseases
Truncation of a P1 leader proteinase facilitates potyvirus replication in a non-permissive host.
Virus Diseases
Turkey adenovirus 3, a siadenovirus, uses sialic acid on N-linked glycoproteins as a cellular receptor.
Virus Diseases
Type-I interferons induce lung protease responses following respiratory syncytial virus infection via RIG-I-like receptors.
Virus Diseases
Ubiquitin-specific protease 14 is a new therapeutic target for the treatment of diseases.
Virus Diseases
Understanding the structural and energetic basis of inhibitor and substrate bound to the full-length NS3/4A: insights from molecular dynamics simulation, binding free energy calculation and network analysis.
Virus Diseases
Versatility at the nuclear pore complex: lessons learned from the nucleoporin Nup153.
Virus Diseases
Viral hepatitis and liver transplantation: pathogenesis, prevention and therapy of recurrent disease.
Virus Diseases
Virological, immunological, and clinical impact of switching from protease inhibitors to nevirapine or to efavirenz in patients with human immunodeficiency virus infection and long-lasting viral suppression.
Virus Diseases
X-ray Structure and Enzymatic Activity Profile of a Core Papain-like Protease of MERS Coronavirus with utility for structure-based drug design.
Virus Diseases
[Antiviral and therapeutic action of protease inhibitors in viral infections: experimental and clinical observations]
Virus Diseases
[Changes in the protease activity in the lungs of mice infected with the influenza A virus]
Virus Diseases
[Clinico-immunologic characteristics of complicated forms of acute respiratory viral diseases in young children and the use of protease inhibitors]
Virus Diseases
[Suppression of the proteolytic activation of myxoviruses in infected chick embryos by using aprotinin]
Vitamin D Deficiency
Airway infection with Nontypeable Haemophilus influenzae is more rapidly eradicated in vitamin D deficient mice.
Vitamin D Deficiency
Brief Report: Markers of Spontaneous Preterm Delivery in Women Living With HIV: Relationship With Protease Inhibitors and Vitamin D.
Vitreoretinopathy, Proliferative
Plasmin is the major protease responsible for processing PDGF-C in the vitreous of patients with proliferative vitreoretinopathy.
Vitreous Detachment
Posterior vitreous detachment induced by nattokinase (subtilisin NAT): a novel enzyme for pharmacologic vitreolysis.
Vitreous Detachment
[Research update of ocriplasmin for symptomatic vitreomacular adhesion].
von Willebrand Disease, Type 1
Abnormality of the N-terminal portion of von Willebrand factor in type IIA and IIC von Willebrand disease.
von Willebrand Disease, Type 2
A case of type 2B von Willebrand disease reverse to normal when treated with high doses of protease inhibitor.
von Willebrand Disease, Type 2
A variant of type II von Willebrand disease with an abnormal triplet structure and discordant effects of protease inhibitors on plasma and platelet von Willebrand factor structure.
von Willebrand Diseases
A case of type 2B von Willebrand disease reverse to normal when treated with high doses of protease inhibitor.
von Willebrand Diseases
A variant of type II von Willebrand disease with an abnormal triplet structure and discordant effects of protease inhibitors on plasma and platelet von Willebrand factor structure.
von Willebrand Diseases
Abnormality of the N-terminal portion of von Willebrand factor in type IIA and IIC von Willebrand disease.
von Willebrand Diseases
Cryosupernatant regulates accumulation of unusually large vWF multimers from endothelial cells.
von Willebrand Diseases
Different organization of von Willebrand factor oligomers in type-2A and -2B von Willebrand disease variants: effects of DDAVP infusion and protease inhibitors.
von Willebrand Diseases
Increased bleeding in HIV-positive haemophiliacs treated with antiretroviral protease inhibitors.
von Willebrand Diseases
Multimeric pattern discrepancy between platelet and plasma von Willebrand factor in type IIC von Willebrand disease.
von Willebrand Diseases
Subunit composition of plasma von Willebrand factor. Cleavage is present in normal individuals, increased in IIA and IIB von Willebrand disease, but minimal in variants with aberrant structure of individual oligomers (types IIC, IID, and IIE).
von Willebrand Diseases
The heterogeneity of type IIA von Willebrand's disease: studies with protease inhibitors.
Vulvodynia
Decreased concentration of protease inhibitors: possible contributors to allodynia and hyperalgesia in women with vestibulodynia.
Warts
Resolution of recalcitrant hand warts in an HIV-infected patient treated with potent antiretroviral therapy.
Warts
The tumor suppressor WARTS activates the Omi / HtrA2-dependent pathway of cell death.
Wasting Disease, Chronic
Cellulose ether treatment in vivo generates chronic wasting disease prions with reduced protease resistance and delayed disease progression.
Wasting Disease, Chronic
Monitoring immune cells trafficking fluorescent prion rods hours after intraperitoneal infection.
Wasting Syndrome
Altered fat distribution in HIV-positive men on nucleoside analog reverse transcriptase inhibitor therapy.
Wasting Syndrome
Characteristics of foot fractures in HIV-infected patients previously treated with tenofovir versus non-tenofovir-containing highly active antiretroviral therapy.
Wasting Syndrome
Enhanced saquinavir exposure in human immunodeficiency virus type 1-infected patients with diarrhea and/or wasting syndrome.
West Nile Fever
Insights to substrate binding and processing by West Nile Virus NS3 protease through combined modeling, protease mutagenesis, and kinetic studies.
Whooping Cough
An extended conformation of calmodulin induces interactions between the structural domains of adenylyl cyclase from Bacillus anthracis to promote catalysis.
Whooping Cough
Bordetella pertussis and Bordetella bronchiseptica filamentous hemagglutinins are processed at different sites.
Whooping Cough
Endothelin inhibits adenylate cyclase and stimulates phosphoinositide hydrolysis in adult cardiac myocytes.
Whooping Cough
Immunoglobulin A with protease activity secreted in human milk activates PAR-2 receptors, of intestinal epithelial cells HT-29, and promotes beta-defensin-2 expression.
Whooping Cough
Inhibition of fetal rat pancreatic beta-cell replication by interleukin-1 beta in vitro is not mediated through pertussis toxin-sensitive G-proteins, a decrease in cyclic AMP, or protease activation.
Whooping Cough
Intestinal secretory factor released by macrophages stimulated with Clostridium difficile toxin A: role of interleukin 1beta.
Whooping Cough
Modulation of the biologic activities of IgE-binding factor. V. The role of glycosylation-enhancing factor and glycosylation-inhibiting factor in determining the nature of IgE-binding factors.
Whooping Cough
Oxidant-mediated activation of cytosolic phospholipase a(2) in pulmonary endothelium: role of protein kinase C alpha and a pertussis toxin-sensitive protein.
Whooping Cough
PAR-2 activation regulates IL-8 and GRO-alpha synthesis by NF-kappaB, but not RANTES, IL-6, eotaxin or TARC expression in nasal epithelium.
Whooping Cough
Peptide mapping studies of the pertussis toxin substrate in human neutrophils, platelets and erythrocytes.
Whooping Cough
Preservation of nasopharyngeal smears for fluorescent antibody detection of Bordetella pertussis.
Whooping Cough
Protease treatment of pertussis toxin identifies the preferential cleavage of the S1 subunit.
Whooping Cough
Proteolytic activation of protein kinase Calpha by peroxynitrite in stimulating cytosolic phospholipase A2 in pulmonary endothelium: involvement of a pertussis toxin sensitive protein.
Whooping Cough
Residues in a conserved ?-helical segment are required for cleavage but not secretion of an Escherichia coli serine protease autotransporter passenger domain.
Whooping Cough
Role of MMP-2 in PKCdelta-mediated inhibition of Na+ dependent Ca2+ uptake in microsomes of pulmonary smooth muscle: involvement of a pertussis toxin sensitive protein.
Whooping Cough
The effect of Bordetella pertussis vaccine on protease sensitivity and on the anaphylactic protease production in rats.
Whooping Cough
[Isolation and characteristics of IgA1 and its use for detecting bacterial IgA1 proteases]
Wilms Tumor
Identification of ovarian genes regulated by follicle-stimulating hormone (Fsh) in vitro during early secondary oocyte growth in coho salmon.
Wilms Tumor
Regulation of HtrA2 on WT1 gene expression under imatinib stimulation and its effects on the cell biology of K562 cells.
Wiskott-Aldrich Syndrome
Tyrosine phosphorylation of WASP promotes calpain-mediated podosome disassembly.
Wolfram Syndrome
A calcium-dependent protease as a potential therapeutic target for Wolfram syndrome.
Wound Infection
Molecular quantification of virulence gene-containing Aeromonas in water samples collected from different drinking water treatment processes.
Wound Infection
Temporal induction of secretory leukocyte protease inhibitor (SLPI) in odontoblasts by lipopolysaccharide and wound infection.
Wound Infection
The characterisation of clinical isolates of Staphylococcus aureus in Ile-Ife, Nigeria.
Wound Infection
Variation of extracellular proteases produced by Vibrio vulnificus clinical isolates: genetic diversity of the metalloprotease gene (vvp), and serine protease secretion by vvp-negative strains.
Xeroderma Pigmentosum
Cytotoxic effects of protease inhibitors on human cells. 1. High sensitivity of xeroderma pigmentosum cells to antipain.
Xeroderma Pigmentosum
Cytotoxic effects of protease inhibitors on human cells. 2. Effect of elastatinal.
Xeroderma Pigmentosum
The Bowman-Birk protease inhibitor enhances clonogenic cell survival of ionizing radiation-treated nucleotide excision repair-competent cells but not of xeroderma pigmentosum cells.
Yellow Fever
A conformational switch high-throughput screening assay and allosteric inhibition of the flavivirus NS2B-NS3 protease.
Yellow Fever
Alboserpin, a factor xa inhibitor from the mosquito vector of yellow Fever, binds heparin and membrane phospholipids and exhibits antithrombotic activity.
Yellow Fever
Characterization of a juvenile hormone-regulated chymotrypsin-like serine protease gene in Aedes aegypti mosquito.
Yellow Fever
Evidence that the N-terminal domain of nonstructural protein NS3 from yellow fever virus is a serine protease responsible for site-specific cleavages in the viral polyprotein.
Yellow Fever
High-resolution structure of a Kazal-type serine protease inhibitor from the dengue vector Aedes aegypti.
Yellow Fever
Increase in the size of the amino acid pool is sufficient to activate translation of early trypsin mRNA in Aedes aegypti midgut.
Yellow Fever
Mutagenesis of the signal sequence of yellow fever virus prM protein: enhancement of signalase cleavage In vitro is lethal for virus production.
Yellow Fever
Recombinant juvenile hormone esterase, an effective tool for modifying juvenile hormone-dependent expression of the early trypsin gene in mosquitoes.
Yellow Fever
Yellow fever virus NS2B-NS3 protease: charged-to-alanine mutagenesis and deletion analysis define regions important for protease complex formation and function.
Zika Virus Infection
Serum Proteomics Reveals Alterations in Protease Activity, Axon Guidance, and Visual Phototransduction Pathways in Infants With In Utero Exposure to Zika Virus Without Congenital Zika Syndrome.
Zika Virus Infection
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Zika Virus Infection
Virtual Screening for Potential Inhibitors of NS3 Protein of Zika Virus.
Zika Virus Infection
Zika Virus Protease Cleavage of Host Protein Septin-2 Mediates Mitotic Defects in Neural Progenitors.
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