Reference on EC 3.4.21.19 - glutamyl endopeptidase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Bjrklind, A.; Jrnvall, H.
Substrate specificity of three different extracellular proteolytic enzymes from Staphylococcus aureus
Biochim. Biophys. Acta
370
524-529
1974
Staphylococcus aureus
Houmard, J.; Drapeau, G.R.
Staphylococcal protease: a proteolytic enzyme specific for glutamoyl bonds
Proc. Natl. Acad. Sci. USA
69
3506-3509
1972
Staphylococcus aureus, Staphylococcus aureus V8
Drapeau, G.R.; Boily, Y.; Houmard, J.
Purification and properties of an extracellular protease of Staphylococcus aureus
J. Biol. Chem.
247
6720-6726
1972
Staphylococcus aureus, Staphylococcus aureus V8
Leshchinskaya, L.B.; Shakirov, E.V.; Itskovitch, E.L.; Balaban, N.P.; Mardanova, A.M.; Sharipova, M.R.; Viryasov, M.B.; Rudenskaya, G.N.; Stepanov, V.M.
Glutamyl endopeptidase of Bacillus intermedius, strain 3-19
FEBS Lett.
404
241-244
1997
Bacillus intermedius, Bacillus intermedius Mrz 19
Stennicke, H.R.; Birktoft, J.J.; Breddam, K.
Characterization of the S1 binding site of the glutamic acid-specific protease from Streptomyces griseus
Protein Sci.
5
2266-2275
1996
Streptomyces griseus
Sellinger, O.Z.; Wolfson, M.F.
Carboxylmethylation affects the proteolysis of myelin basic protein by Staphylococcus aureus V8 proteinase
Biochim. Biophys. Acta
1080
110-118
1991
Staphylococcus aureus, Staphylococcus aureus V8
Leshchinskaya, I.B.; Shakirov, E.V.; Itskovitch, E.L.; Balaban, N.P.; Mardanova, A.M.; Sharipova, M.R.; Blagova, E.V.; Levdikov, V.M.; Kuranova, I.P.; Rudenskaya, G.N.; Stepanov, V.M.
Glutamyl endopeptidase of Bacillus intermedius strain 3-19. Purification, properties, and crystallization
Biochemistry
62
903-908
1997
Bacillus intermedius, Bacillus intermedius Mrz 19
Park, O.; Allen, J.C.
Preparation of phosphopeptides derived from alpha s-casein and beta-casein using immobilized glutamic acid-specific endopeptidase and characterization of their calcium binding
J. Dairy Sci.
81
2858-2865
1998
Bacillus licheniformis
Kakudo, S.; Kikuchi, N.; Kitadokoro, K.; Fujiwaera, T.; Nakamura, E.; Okamoto, H.; Shin, M.; Tamaki, M.; Teraoka, H.; Tsuzuki, H.; Yoshida, N.
Purification, characterization, cloning, and expression of a glutamic acid-specific protease from Bacillus licheniformis ATCC 14580
J. Biol. Chem.
267
23782-23788
1992
Bacillus licheniformis, Staphylococcus aureus
Prasad, L.; Leduc, Y.; Hayakawa, K.; Delbaere, L.T.
The structure of a universally employed enzyme: V8 protease from Staphylococcus aureus
Acta Crystallogr. Sect. D
60
256-259
2004
Staphylococcus aureus
Meijers, R.; Blagova, E.V.; Levdikov, V.M.; Rudenskaya, G.N.; Chestukhina, G.G.; Akimkina, T.V.; Kostrov, S.V.; Lamzin, V.S.; Kuranova, I.P.
The crystal structure of glutamyl endopeptidase from Bacillus intermedius reveals a structural link between zymogen activation and charge compensation
Biochemistry
43
2784-2791
2004
Bacillus intermedius
Balaban, N.P.; Mardanova, A.M.; Sharipova, M.R.; Gabdrakhmanova, L.A.; Sokolova, E.A.; Garusov, A.V.; Milgotina, E.I.; Rudenskaya, G.N.; Leshchinskaya, I.B.
Isolation and characterization of glutamyl endopeptidase 2 from Bacillus intermedius 3-19
Biochemistry (Moscow)
68
1217-1224
2003
Bacillus intermedius, Bacillus intermedius Mrz 19
Wehofsky, N.; Wissmann, J.D.; Alisch, M.; Bordusa, F.
Engineering of substrate mimetics as novel-type substrates for glutamic acid-specific endopeptidases: design, synthesis, and application
Biochim. Biophys. Acta
1479
114-122
2000
Bacillus licheniformis, Staphylococcus aureus
Gabdrakhmanova, L.A.; Balaban, N.P.; Sharipova, M.R.; Kostrov, S.V.; Akimkina, T.V.; Rudenskaya, G.N.; Leshchinskaya, I.B.
Optimization of Bacillus intermedius glutamyl endopeptidase production by recombinant strain of Bacillus subtilis and localization of glutamyl endopeptidase in Bacillus subtilis cells
Enzyme Microb. Technol.
31
256-263
2002
Bacillus intermedius
-
Srinivasulu, S.; Acharya, A.S.
Product-conformation-driven ligation of peptides by V8 protease
Protein Sci.
11
1384-1392
2002
Staphylococcus aureus
Mil'gotina, E.I.; Voyushina, T.L.; Chestukhina, G.G.
Glutamyl endopeptidases: structure, function, and practical application
Russ. J. Bioorg. Chem.
29
511-522
2003
Bacillus subtilis, Bacillus licheniformis, Staphylococcus aureus, Streptomyces griseus, Staphylococcus aureus V8
-
Trachuk, L.A.; Shcheglov, A.S.; Milgotina, E.I.; Chestukhina, G.G.
In vitro maturation pathway of a glutamyl endopeptidase precursor from Bacillus licheniformis
Biochimie
87
529-537
2005
Bacillus licheniformis
Kawalec, M.; Potempa, J.; Moon, J.L.; Travis, J.; Murray, B.E.
Molecular diversity of a putative virulence factor: purification and characterization of isoforms of an extracellular serine glutamyl endopeptidase of Enterococcus faecalis with different enzymatic activities
J. Bacteriol.
187
266-275
2005
Enterococcus faecalis (Q47809), Enterococcus faecalis, Enterococcus faecalis OG1RF (Q47809)
Seeley, E.H.; Riggs, L.D.; Regnier, F.E.
Reduction of non-specific binding in Ga(III) immobilized metal affinity chromatography for phosphopeptides by using endoproteinase glu-C as the digestive enzyme
J. Chromatogr. B
817
81-88
2005
Staphylococcus aureus
Chastukhina, I.B.; Sharipova, M.R.; Gabdrakhmanova, L.A.; Balaban, N.P.; Safina, D.R.; Kostrov, S.V.; Rudenskaya, G.N.; Leshchinskaya, I.B.
The regulation of Bacillus intermedius glutamyl endopeptidase biosynthesis in the recombinant Bacillus subtilis strain AJ73 during sporulation
Microbiology
73
279-285
2004
Bacillus intermedius
-
Chastukhina, I.B.; Sharipova, M.R.; Gabdrakhmanova, L.A.; Balaban, N.P.; Kostrov, S.V.; Rudenskaya, G.N.; Leshchinskaya, I.B.
Peculiarities of the biosynthesis of Bacillus intermedius glutamyl endopeptidase in recombinant Bacillus subtilis cells during the stationary growth phase
Microbiology
74
32-39
2005
Bacillus intermedius
-
Forsberg, J.; Stroem, J.; Kieselbach, T.; Larsson, H.; Alexciev, K.; Engstroem, A.; Akerlund, H.
Protease activities in the chloroplast capable of cleaving an LHCII N-terminal peptide
Physiol. Plant.
123
21-29
2005
Pisum sativum
-
Demidyuk, I.V.; Romanova, D.V.; Nosovskaya, E.A.; Chestukhina, G.G.; Kuranova, I.P.; Kostrov, S.V.
Modification of substrate-binding site of glutamyl endopeptidase from Bacillus intermedius
Protein Eng. Des. Sel.
17
411-416
2004
Bacillus intermedius
Nemoto, T.K.; Ohara-Nemoto, Y.; Ono, T.; Kobayakawa, T.; Shimoyama, Y.; Kimura, S.; Takagi, T.
Characterization of the glutamyl endopeptidase from Staphylococcus aureus expressed in Escherichia coli
FEBS J.
275
573-587
2008
Staphylococcus aureus, Staphylococcus epidermidis
Shagimardanova, E.I.; Chastukhina, I.B.; Shamsutdinov, T.R.; Balaban, N.P.; Mardanova, A.M.; Kostrov, S.V.; Sharipova, M.R.
Heterologous expression of Bacillus intermedius gene of glutamyl endopeptidase in Bacillus subtilis strains defective in regulatory proteins
Microbiology
76
569-574
2007
Bacillus intermedius
-
Sharipova, M.R.; Shagimardanova, E.I.; Chastukhina, I.B.; Shamsutdinov, T.R.; Balaban, N.P.; Mardanova, A.M.; Rudenskaya, G.N.; Demidyuk, I.V.; Kostrov, S.V.
The expression of Bacillus intermedius glutamyl endopeptidase gene in Bacillus subtilis recombinant strains
Mol. Biol. Rep.
34
79-87
2007
Bacillus intermedius (Q9EXR9), Bacillus intermedius
Ono, T.; Nemoto, T.K.; Shimoyama, Y.; Kimura, S.; Ohara-Nemoto, Y.
An Escherichia coli expression system for glutamyl endopeptidases optimized by complete suppression of autodegradation
Anal. Biochem.
381
74-80
2008
Staphylococcus aureus, Staphylococcus epidermidis, Staphylococcus warneri, Staphylococcus warneri JCM 2415, Staphylococcus aureus V8
Ohara-Nemoto, Y.; Ono, T.; Shimoyama, Y.; Kimura, S.; Nemoto, T.K.
Homologous and heterologous expression and maturation processing of extracellular glutamyl endopeptidase of Staphylococcus epidermidis
Biol. Chem.
389
1209-1217
2008
Staphylococcus epidermidis (P0C0Q1), Staphylococcus epidermidis
Nemoto, T.K.; Ono, T.; Shimoyama, Y.; Kimura, S.; Ohara-Nemoto, Y.
Determination of three amino acids causing alteration of proteolytic activities of staphylococcal glutamyl endopeptidases
Biol. Chem.
390
277-285
2008
Staphylococcus aureus, Staphylococcus epidermidis, Staphylococcus warneri
Gasanov, E.V.; Demidyuk, I.V.; Shubin, A.V.; Kozlovskiy, V.I.; Leonova, O.G.; Kostrov, S.V.
Hetero- and auto-activation of recombinant glutamyl endopeptidase from Bacillus intermedius
Protein Eng. Des. Sel.
21
653-658
2008
Bacillus intermedius (Q9EXR9), Bacillus intermedius
Boulais, P.E.; Dulude, D.; Cabana, J.; Heveker, N.; Escher, E.; Lavigne, P.; Leduc, R.
Photolabeling identifies transmembrane domain 4 of CXCR4 as a T140 binding site
Biochem. Pharmacol.
78
1382-1390
2009
Staphylococcus aureus
Murai, M.; Sekiguchi, K.; Nishioka, T.; Miyoshi, H.
Characterization of the inhibitor binding site in mitochondrial NADH-ubiquinone oxidoreductase by photoaffinity labeling using a quinazoline-type inhibitor
Biochemistry
48
688-698
2009
Staphylococcus aureus
Tubby, S.; Wilson, M.; Nair, S.P.
Inactivation of staphylococcal virulence factors using a light-activated antimicrobial agent
BMC Microbiol.
9
211
2009
Staphylococcus aureus
Dolcini, L.; Sala, A.; Campagnoli, M.; Labo, S.; Valli, M.; Visai, L.; Minchiotti, L.; Monaco, H.L.; Galliano, M.
Identification of the amniotic fluid insulin-like growth factor binding protein-1 phosphorylation sites and propensity to proteolysis of the isoforms
FEBS J.
276
6033-6046
2009
Staphylococcus aureus
Such-Sanmartin, G.; Bosch, J.; Segura, J.; Gutierrez-Gallego, R.
Generation of 5 and 17 kDa human growth hormone fragments through limited proteolysis
Growth Factors
27
255-264
2009
Staphylococcus aureus
Guedes, S.; Vitorino, R.; Domingues, M.R.; Amado, F.; Domingues, P.
Mass spectrometry characterization of the glycation sites of bovine insulin by tandem mass spectrometry
J. Am. Soc. Mass Spectrom.
20
1319-1326
2009
Staphylococcus aureus
Schmidtchen, A.; Pasupuleti, M.; Moergelin, M.; Davoudi, M.; Alenfall, J.; Chalupka, A.; Malmsten, M.
Boosting antimicrobial peptides by hydrophobic oligopeptide end tags
J. Biol. Chem.
284
17584-17594
2009
Staphylococcus aureus
Kwak, Y.K.; Hoegbom, M.; Colque-Navarro, P.; Moellby, R.; Vecsey-Semjen, B.
Biological relevance of natural alpha-toxin fragments from Staphylococcus aureus
J. Membr. Biol.
233
93-103
2010
Staphylococcus aureus, Staphylococcus aureus Wood 46
Boudier, C.; Klymchenko, A.S.; Mely, Y.; Follenius-Wund, A.
Local environment perturbations in alpha1-antitrypsin monitored by a ratiometric fluorescent label
Photochem. Photobiol. Sci.
8
814-821
2009
Staphylococcus aureus
Mateos, A.; Girardet, J.M.; Molle, D.; Corbier, C.; Gaillard, J.L.; Miclo, L.
Identification of phosphorylation sites of equine beta-casein isoforms
Rapid Commun. Mass Spectrom.
24
1533-1542
2010
Staphylococcus aureus, Staphylococcus aureus V8
Ono, T.; Ohara-Nemoto, Y.; Shimoyama, Y.; Okawara, H.; Kobayakawa, T.; Baba, T.T.; Kimura, S.; Nemoto, T.K.
Amino acid residues modulating the activities of staphylococcal glutamyl endopeptidases
Biol. Chem.
391
1221-1232
2010
Staphylococcus aureus, Staphylococcus epidermidis, Staphylococcus saprophyticus, Staphylococcus warneri, Staphylococcus cohnii subsp. cohnii, Staphylococcus caprae, Staphylococcus aureus ATCC 25923, Staphylococcus cohnii subsp. cohnii GTC 248, Staphylococcus caprae GTC 378, Staphylococcus warneri JCM 2415, Staphylococcus epidermidis ATCC 14990
Park, J.W.; Park, J.E.; Park, J.K.; Lee, J.S.
Purification and biochemical characterization of a novel glutamyl endopeptidase secreted by a clinical isolate of Staphylococcus aureus
Int. J. Mol. Med.
27
637-645
2011
Staphylococcus aureus, Staphylococcus aureus C-66
Craig, M.; Amiri, M.; Holmberg, K.
Bacterial protease triggered release of biocides from microspheres with an oily core
Colloids Surf. B Biointerfaces
127C
200-205
2015
Staphylococcus aureus
Kalyankar, P.; Zhu, Y.; OKeeffe, M.; OCuinn, G.; FitzGerald, R.J.
Substrate specificity of glutamyl endopeptidase (GE): hydrolysis studies with a bovine alpha-casein preparation
Food Chem.
136
501-512
2013
Bacillus licheniformis
Zhu, Y.S.; Kalyankar, P.; FitzGerald, R.J.
Relative quantitation analysis of the substrate specificity of glutamyl endopeptidase with bovine alpha-caseins
Food Chem.
167
463-467
2015
Bacillus licheniformis
Kalyankar, P.; Zhu, Y.; OCuinn, G.; FitzGerald, R.J.
Investigation of the substrate specificity of glutamyl endopeptidase using purified bovine beta-casein and synthetic peptides
J. Agric. Food Chem.
61
3193-3204
2013
Bacillus licheniformis
Liu, F.; Zhao, Z.S.; Ren, Y.; Cheng, G.; Tang, X.F.; Tang, B.
Autocatalytic activation of a thermostable glutamyl endopeptidase capable of hydrolyzing proteins at high temperatures
Appl. Microbiol. Biotechnol.
100
10429-10441
2016
Thermoactinomyces sp. CDF
Elmwall, J.; Kwiecinski, J.; Na, M.; Ali, A.A.; Osla, V.; Shaw, L.N.; Wang, W.; Saevman, K.; Josefsson, E.; Bylund, J.; Jin, T.; Welin, A.; Karlsson, A.
Galectin-3 is a target for proteases involved in the virulence of Staphylococcus aureus
Infect. Immun.
85
e00177-17
2017
Staphylococcus aureus (Q2FZL2), Staphylococcus aureus, Staphylococcus aureus NCTC 8325 (Q2FZL2)
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