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Information on EC 3.4.21.113 - pestivirus NS3 polyprotein peptidase

for references in articles please use BRENDA:EC3.4.21.113
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The enzyme appears in viruses and cellular organisms
Reaction Schemes
Leu is conserved at position P1 for all four cleavage sites. Alanine is found at position P1' of the NS4A-NS4B cleavage site, whereas serine is found at position P1' of the NS3-NS4A, NS4B-NS5A and NS5A-NS5B cleavage sites
Synonyms
nonstructural protein ns3, wnv ns2b/ns3, flavivirus ns3 protease, more
REACTION
REACTION DIAGRAM
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ORGANISM
UNIPROT
LITERATURE
Leu is conserved at position P1 for all four cleavage sites. Alanine is found at position P1' of the NS4A-NS4B cleavage site, whereas serine is found at position P1' of the NS3-NS4A, NS4B-NS5A and NS5A-NS5B cleavage sites
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