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Information on EC 3.4.21.113 - pestivirus NS3 polyprotein peptidase

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Word Map
The enzyme appears in viruses and cellular organisms
Reaction Schemes
Leu is conserved at position P1 for all four cleavage sites. Alanine is found at position P1' of the NS4A-NS4B cleavage site, whereas serine is found at position P1' of the NS3-NS4A, NS4B-NS5A and NS5A-NS5B cleavage sites
Synonyms
nonstructural protein ns3, csfv ns3, wnv ns2b/ns3, flavivirus ns3 protease, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
Leu is conserved at position P1 for all four cleavage sites. Alanine is found at position P1' of the NS4A-NS4B cleavage site, whereas serine is found at position P1' of the NS3-NS4A, NS4B-NS5A and NS5A-NS5B cleavage sites
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