Reference on EC 3.4.21.1 - chymotrypsin
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Stein, R.L.; Strimpler, A.M.
Slow-binding inhibition of chymotrypsin and cathepsin G by the peptide aldehyde chymostatin
Biochemistry
26
2611-2615
1987
Bos taurus
Guyonnet, V.; Tluscik, F.; Long, P.L.; Polanowski, A.; Travis, J.
Purification and partial characterization of the pancreatic proteolytic enzymes trypsin, chymotrypsin and elastase from the chicken
J. Chromatogr.
852
217-225
1999
Gallus gallus
Rick, W.
Chymotrypsin
Methods Enzym. Anal. , 3rd Ed. (Bergmeyer, H. U. , ed. )
1
1045-1051
1974
Bos taurus
-
Ryan, C.A
Chicken chymotrypsin and turkey trypsin. Part I: Purification
Arch. Biochem. Biophys.
110
169-174
1965
Gallus gallus
Ryan, C.A.; Clary, J.J.; Tomimatsu, Y.
Chicken chymotrypsin and turkey trypsin. Part II: Physical and enzymatic properties
Arch. Biochem. Biophys.
110
175-183
1965
Gallus gallus
Williams, D.A.; Batt, R.M.; Beynon, R.J.
A simple procedure for purification of the zymogens and active forms of canine anionic trypsin, cationic trypsin and chymotrypsin
Biochem. Soc. Trans.
11
351
1983
Canis lupus familiaris
-
Ascenzi, P.; Menegatti, E.; Guarneri, M.; Bortolotti, F.; Antonini, E.
Catalytic properties of serine proteases. 2. Comparison between human urinary kallikrein and human urokinase, bovine beta-trypsin, bovine thrombin, and bovine alpha-chymotrypsin
Biochemistry
21
2483-2490
1982
Bos taurus
Bolognesi, M.; Pugliese, L.; Gatti, G.; Frigerio, F.; Coda, A.; Antolini, L.; Schnebli, H.P.; Menegatti, E.; Amiconi, G.; Ascenzi, P.
X-ray crystal structute of the bovine alpha-chymotrypsin/eglin c complex at 2.6 A resolution
J. Mol. Recognit.
3
163-168
1990
Bos taurus
Capasso, C.; Rizzi, M.; Menegatti, E.; Ascenzi, P.; Bolognesi, M.
Crystal structure of the bovine alpha-chymotrypsin:Kunitz inhibitor complex. An example of multiple protein:protein recognition sites
J. Mol. Recognit.
10
26-35
1997
Bos taurus
Scheidig, A.J.; Hynes, T.R.; Pelletier, L.A.; Wells, J.A.; Kossiakoff, A.A.
Crystal structures of bovine chymotrypsin and trypsin complexed to the inhibitors domain of Alzheimer's amyloid beta-protein precursor (APPI) and basic pancreatic trypsin inhibitor (BPTI): engineering of inhibitors with altered specificities
Protein Sci.
6
1806-1824
1997
Bos taurus
Asgeirsson, B.; Bjarnason, J.B.
Structural and kinetic properties of chymotrypsin from atlantic cod (Gadus morhua). Comparison with bovine chymotrypsin
Comp. Biochem. Physiol. B
99B
327-335
1991
Bos taurus, Gadus morhua
von Deimling, O.H.; Grning, J.; Gaa, A.
Genetic and biochemical characterization of a new chymotrypsin isozyme of the house mouse, CTRA-1
Biochem. Genet.
29
545-557
1991
Mus musculus
Casu, R.E.; Pearson, R.D.; Jarmey, J.M.; Cadogan, L.C.; Riding, G.A.; Tellam, R.L.
Excretory/secretory chymotrypsin from Lucilia cuprina: purification, enzymatic specificity and amino acid sequence deduced from mRNA
Insect Mol. Biol.
3
201-211
1994
Lucilia cuprina
Al-Ajlan, A.; Bailey, G.S.
Purification and partial characterization of camel anionic chymotrypsin
Arch. Biochem. Biophys.
348
363-368
1997
Bos taurus, Camelus bactrianus
Cutruzzola, F.; Ascenzi, P.; Barra, D.; Bolognesi, M.; Menegatti, E.; Sarti, P.; Schnebli, H.P.; Tomova, S.; Amiconi, G.
Selective oxidation of Met-192 in bovine alpha-chymotrypsin. Effect on catalytic and inhibitor binding properties
Biochim. Biophys. Acta
1161
201-208
1993
Bos taurus
Carrea, G.; Pasta, P.; Antonini, E.
Purification of chymotrypsin by subunit exchange chromatography on the denatured protein
Biotechnol. Bioeng.
25
1331-1339
1983
Bos taurus, Sus scrofa
Peterson, A.M.; Fernando, G.J.P.; Wells, M.A.
Purification, characterization and cDNA sequence of an alkaline chymotrypsin from the midgut of Manduca sexta
Insect Biochem. Mol. Biol.
25
765-774
1995
Manduca sexta
Fioretti, E.; Angeletti, M.; Lupidi, G.; Coletta, M.
Heterotropic modulation of the protease-inhibitor-recognition process. Cations effect the binding properties of alpha-chymotrypsin
Eur. J. Biochem.
225
459-465
1994
Bos taurus
Birk, Y.
A trypsin and chymotrypsin inhibitor from groundnuts (Arachis hypogaea)
Methods Enzymol.
45
716-722
1976
Bos taurus
Simon, L.M.; Kotorman, M.; Garab, G.; Laczko, I.
Structure and activity of alpha-chymotrypsin and trypsin in aqueous organic media
Biochem. Biophys. Res. Commun.
280
1367-1371
2001
Bos taurus
Ye, X.Y.; Ng, T.B.; Rao, P.F.
A Bowman-Birk-type trypsin-chymotrypsin inhibitor from broad beans
Biochem. Biophys. Res. Commun.
289
91-96
2001
Bos taurus
Simon, L.M.; Kotorman, M.; Garab, G.; Laczko, I.
Effects of polyhydroxy compounds on the structure and activity of alpha-chymotrypsin
Biochem. Biophys. Res. Commun.
293
416-420
2002
Bos taurus
Kotorman, M.; Laczko, I.; Szabo, A.; Simon, L.M.
Effects of Ca2+ on catalytic activity and conformation of trypsin and alpha-chymotrypsin in aqueous ethanol
Biochem. Biophys. Res. Commun.
304
18-21
2003
Bos taurus
Simon, L.M.; Kotorman, M.; Szabo, A.; Garab, G.; Laczko, I.
Effects of polyethylene glycol on stability of alpha-chymotrypsin in aqueous ethanol solvent
Biochem. Biophys. Res. Commun.
317
610-613
2004
Bos taurus
Djurdjevic-Pahl, A.; Hewage, C.; Malthouse, J.P.
13C-NMR study of the inhibition of delta-chymotrypsin by a tripeptide-glyoxal inhibitor
Biochem. J.
362
339-347
2002
Bos taurus
Case, A.; Huskey, W.P.; Stein, R.L.
Enzymatic reaction of silent substrates: kinetic theory and application to the serine protease chymotrypsin
Biochemistry
42
4727-4732
2003
Bos taurus
Belyaeva, E.A.; Gra, D.V.; Eremeev, N.L.
On the mechanism of interaction of organic solvents with the active site of alpha-chymotrypsin
Biochemistry (Moscow)
67
1032-1036
2002
Bos taurus
Wesolowska, O.; Krokoszynska, I.; Krowarsch, D.; Otlewski, J.
Enhancement of chymotrypsin-inhibitor/substrate interactions by 3 M NaCl
Biochim. Biophys. Acta
1545
78-85
2001
Bos taurus
Kiczak, L.; Kasztura, M.; Koscielska-Kasprzak, K.; Dadlez, M.; Otlewski, J.
Selection of potent chymotrypsin and elastase inhibitors from M13 phage library of basic pancreatic trypsin inhibitor (BPTI)
Biochim. Biophys. Acta
1550
153-163
2001
Bos taurus
Thompson, V.F.; Lawson, K.R.; Barlow, J.; Goll, D.E.
Digestion of mu- and m-calpain by trypsin and chymotrypsin
Biochim. Biophys. Acta
1648
140-153
2003
Bos taurus
Poerio, E.; Di Gennaro, S.; Di Maro, A.; Farisei, F.; Ferranti, P.; Parente, A.
Primary structure and reactive site of a novel wheat proteinase inhibitor of subtilisin and chymotrypsin
Biol. Chem.
384
295-304
2003
Bos taurus, Sus scrofa
Smoum, R.; Rubinstein, A.; Srebnik, M.
A study of the effect on nucleophilic hydrolytic activity of pancreatic elastase, trypsin, chymotrypsin, and leucine aminopeptidase by boronic acids in the presence of arabinogalactan: a subsequent study on the hydrolytic activity of chymotrypsin by boronic acids in the presence of mono-, di-, and trisaccharides
Bioorg. Chem.
31
464-474
2003
Bos taurus
Pochet, L.; Doucet, C.; Dive, G.; Wouters, J.; Masereel, B.; Reboud-Ravaux, M.; Pirotte, B.
Coumarinic derivatives as mechanism-based inhibitors of alpha-chymotrypsin and human leukocyte elastase
Bioorg. Med. Chem.
8
1489-1501
2000
Bos taurus
Abell, A.D.; Nabbs, B.K.
Ring-deactivated hydroxymethylpyrroles as inhibitors of alpha-chymotrypsin
Bioorg. Med. Chem.
9
621-628
2001
Bos taurus
Han, M.S.; Oh, D.J.; Kim, D.H.
Inhibition of alpha-chymotrypsin with thiol-bearing substrate analogues in the presence of zinc ion
Bioorg. Med. Chem. Lett.
14
701-705
2004
Bos taurus
Sato, M.; Sasaki, T.; Kobayashi, M.; Kise, H.
Time-dependent structure and activity changes of alpha-chymotrypsin in water/alcohol mixed solvents
Biosci. Biotechnol. Biochem.
64
2552-2558
2000
Bos taurus
Fernandez, M.; Villalonga Mde, L.; Fragoso, A.; Cao, R.; Villalonga, R.
Stabilization of alpha-chymotrypsin by modification with beta-cyclodextrin derivatives
Biotechnol. Appl. Biochem.
36
235-239
2002
Bos taurus
Fadnavis, N.W.; Bhaskar, V.; Kantam, M.L.; Choudary, B.M.
Highly efficient "tight fit" immobilization of alpha-chymotrypsin in mesoporous MCM-41: a novel approach using precursor immobilization and activation
Biotechnol. Prog.
19
346-351
2003
Bos taurus
Gunther, R.; Thust, S.; Hofmann, H.J.; Bordusa, F.
Trypsin-specific acyl-4-guanidinophenyl esters for alpha-chymotrypsin-catalysed reactions computational predictions, hydrolyses, and peptide bond formation
Eur. J. Biochem.
267
3496-3501
2000
Bos taurus
Bodi, A.; Kaslik, G.; Venekei, I.; Graf, L.
Structural determinants of the half-life and cleavage site preference in the autolytic inactivation of chymotrypsin
Eur. J. Biochem.
268
6238-6246
2001
Rattus norvegicus
Spreti, N.; Di Profio, P.; Marte, L.; Bufali, S.; Brinchi, L.; Savelli, G.
Activation and stabilization of alpha-chymotrypsin by cationic additives
Eur. J. Biochem.
268
6491-6497
2001
Bos taurus
Yakoby, N.; Raskin, I.
A simple method to determine trypsin and chymotrypsin inhibitory activity
J. Biochem. Biophys. Methods
59
241-251
2004
Bos taurus
Screen, S.E.; St.Leger, R.J.
Cloning, expression, and substrate specificity of a fungal chymotrypsin. Evidence for lateral gene transfer from an actinomycete bacterium
J. Biol. Chem.
275
6689-6694
2000
Metarhizium anisopliae (Q9Y843), Metarhizium anisopliae
Roussel, A.; Mathieu, M.; Dobbs, A.; Luu, B.; Cambillau, C.; Kellenberger, C.
Complexation of two proteic insect inhibitors to the active site of chymotrypsin suggests decoupled roles for binding and selectivity
J. Biol. Chem.
276
38893-38898
2001
Bos taurus
O'Malley, K.M.; Cooperman, B.S.
Formation of the covalent chymotrypsin.antichymotrypsin complex involves no large-scale movement of the enzyme
J. Biol. Chem.
276
6631-6639
2001
Bos taurus
Kolodziej, S.J.; Wagenknecht, T.; Strickland, D.K.; Stoops, J.K.
The three-dimensional structure of the human alpha 2-macroglobulin dimer reveals its structural organization in the tetrameric native and chymotrypsin alpha 2-macroglobulin complexes
J. Biol. Chem.
277
28031-28037
2002
Bos taurus
Chopin, V.; Stefano, G.; Salzet, M.
Biochemical evidence of specific trypsin-chymotrypsin inhibitors in the rhynchobdellid leech, Theromyzon tessulatum
J. Enzyme Inhib.
15
367-379
2000
Bos taurus
Botos, I.; Meyer, E.; Nguyen, M.; Swanson, S.M.; Koomen, J.M.; Russell, D.H.; Meyer, E.F.
The structure of an insect chymotrypsin
J. Mol. Biol.
298
895-901
2000
Solenopsis invicta (Q7SIG2)
Ghani, U.; Ng, K.K.; Atta ur, R.; Choudhary, M.I.; Ullah, N.; James, M.N.
Crystal structure of gamma-chymotrypsin in complex with 7-hydroxycoumarin
J. Mol. Biol.
314
519-525
2001
Bos taurus (P00766)
Al-Ajlan, A.; Bailey, G.S.
Purification and characterization of cationic chymotrypsin from the pancreas of the Arabian camel (Camelus dromedarius)
Mol. Cell. Biochem.
203
73-78
2000
Bos taurus, Camelus dromedarius
Komada, A.; Yamauchi, Y.; Ikesue, K.; Fujita, T.; Nose, T.; Sakaguchi, K.; Shimohigashi, Y.
Characteristic intra- and intermolecular interactions of dipeptide-chymotrypsin complex as specific structural essentials for enzyme inhibition
Pept. Sci.
38
179-182
2002
Bos taurus
-
Rajic, A.; Akihisa, T.; Ukiya, M.; Yasukawa, K.; Sandeman, R.M.; Chandler, D.S.; Polya, G.M.
Inhibition of trypsin and chymotrypsin by anti-inflammatory triterpenoids from Compositae flowers
Planta Med.
67
599-604
2001
Bos taurus
Fischer, N.O.; McIntosh, C.M.; Simard, J.M.; Rotello, V.M.
Inhibition of chymotrypsin through surface binding using nanoparticle-based receptors
Proc. Natl. Acad. Sci. USA
99
5018-5023
2002
Bos taurus
Ulitina, N.N.; Khablyuk, V.V.; Proskuryakov, M.T.
Purification and properties of serine proteinases from European catfish Silurus glanis L. pancreas
Appl. Biochem. Microbiol.
41
139-144
2005
Silurus glanis
-
Celej, M.S.; Dandrea, M.G.; Campana, P.T.; Fidelio, G.D.; Bianconi, M.L.
Superactivity and conformational changes on alpha-chymotrypsin upon interfacial binding to cationic micelles
Biochem. J.
378
1059-1066
2004
Bos taurus
Hengge, A.C.; Stein, R.L.
Role of protein conformational mobility in enzyme catalysis: acylation of alpha-chymotrypsin by specific peptide substrates
Biochemistry
43
742-747
2004
Bos taurus
Castillo, B.; Mendez, J.; Al-Azzam, W.; Barletta, G.; Griebenow, K.
On the relationship between the activity and structure of PEG-alpha-chymotrypsin conjugates in organic solvents
Biotechnol. Bioeng.
94
565-574
2006
Homo sapiens
von Elert, E.; Agrawal, M.K.; Gebauer, C.; Jaensch, H.; Bauer, U.; Zitt, A.
Protease activity in gut of Daphnia magna: evidence for trypsin and chymotrypsin enzymes
Comp. Biochem. Physiol. B Biochem. Mol. Biol.
137
287-296
2004
Daphnia magna
Tardioli, P.W.; Sousa, R.J.; Giordano, R.C.; Giordano, R.L.
Kinetic model of the hydrolysis of polypeptides catalyzed by alcalase immobilized on 10% glyoxyl-agarose
Enzyme Microb. Technol.
36
555-564
2005
Bos taurus
-
Singh, N.; Jabeen, T.; Sharma, S.; Roy, I.; Gupta, M.N.; Bilgrami, S.; Somvanshi, R.K.; Dey, S.; Perbandt, M.; Betzel, C.; Srinivasan, A.; Singh, T.P.
Detection of native peptides as potent inhibitors of enzymes. Crystal structure of the complex formed between treated bovine alpha-chymotrypsin and an autocatalytically produced fragment, IIe-Val-Asn-Gly-Glu-Glu-Ala-Val-Pro-Gly-Ser-Trp-Pro-Trp, at 2.2 angstroms resolution
FEBS J.
272
562-572
2005
Bos taurus
Nemoda, Z.; Sahin-Toth, M.
Chymotrypsin C (caldecrin) stimulates autoactivation of human cationic trypsinogen
J. Biol. Chem.
281
11879-11886
2006
Homo sapiens
Abuin, E.; Lissi, E.; Duarte, R.
Kinetics of N-glutaryl-L-phenylalanine p-nitroanilide hydrolysis catalyzed by alpha-chymotrypsin in aqueous solutions of dodecyltrimethylammonium bromide
J. Colloid Interface Sci.
283
539-543
2005
Bos taurus
Czapinska, H.; Helland, R.; Smalas, A.O.; Otlewski, J.
Crystal structures of five bovine chymotrypsin complexes with P1 BPTI variants
J. Mol. Biol.
344
1005-1020
2004
Bos taurus
Thompson, S.; Fawcett, M.C.; Pulman, L.B.; Self, C.H.
A simple procedure for the photoregulation of chymotrypsin activity
Photochem. Photobiol. Sci.
5
326-330
2006
Bos taurus
Matrai, J.; Verheyden, G.; Krueger, P.; Engelborghs, Y.
Simulation of the activation of alpha-chymotrypsin: analysis of the pathway and role of the propeptide
Protein Sci.
13
3139-3150
2004
Bos taurus, Rattus norvegicus
Esteves, G.F.; Teles, R.C.; Cavalcante, N.S.; Neves, D.; Ventura, M.M.; Barbosa, J.A.; de Freitas, S.M.
Crystallization, data collection and processing of the chymotrypsin-BTCI-trypsin ternary complex
Acta Crystallogr. Sect. F
63
1087-1090
2007
Bos taurus (P00766)
Shaw, A.; Saldajeno, M.L.; Kolkman, M.A.; Jones, B.E.; Bott, R.
Structure determination and analysis of a bacterial chymotrypsin from Cellulomonas bogoriensis
Acta Crystallogr. Sect. F
F63
266-269
2007
Cellulomonas bogoriensis
Walters, F.S.; Stacy, C.M.; Lee, M.K.; Palekar, N.; Chen, J.S.
An engineered chymotrypsin/cathepsin G site in domain I renders Bacillus thuringiensis Cry3A active against Western corn rootworm larvae
Appl. Environ. Microbiol.
74
367-374
2008
Diabrotica virgifera
Spink, E.; Hewage, C.; Malthouse, J.P.
Determination of the structure of tetrahedral transition state analogues bound at the active site of chymotrypsin using 18O and 2H isotope shifts in the 13C NMR spectra of glyoxal inhibitors
Biochemistry
46
12868-12874
2007
Bos taurus
Moulin, A.; Bell, J.H.; Pratt, R.F.; Ringe, D.
Inhibition of chymotrypsin by a complex of ortho-vanadate and benzohydroxamic acid: structure of the inert complex and its mechanistic interpretation
Biochemistry
46
5982-5990
2007
Bos taurus (P00766)
Rezaei-Ghaleh, N.; Ramshini, H.; Ebrahim-Habibi, A.; Moosavi-Movahedi, A.A.; Nemat-Gorgani, M.
Thermal aggregation of alpha-chymotrypsin: role of hydrophobic and electrostatic interactions
Biophys. Chem.
132
23-32
2008
Bos taurus
You, C.; Arvizo, R.R.; Rotello, V.M.
Regulation of alpha-chymotrypsin activity on the surface of substrate-functionalized gold nanoparticles
Chem. Commun. (Camb. )
2006
2905-2907
2006
Bos taurus
-
Castillo-Yanez, F.J.; Pacheco-Aguilar, R.; Garcia-Carreno, F.L.; de los Angeles Navarrete-Del Toro, M.; Lopez, M.F.
Purification and biochemical characterization of chymotrypsin from the viscera of Monterey sardine (Sardinops sagax caeruleus)
Food Chem.
99
252-259
2006
Sardinops sagax
Rezaei-Ghaleh, N.; Ebrahim-Habibi, A.; Moosavi-Movahedi, A.A.; Nemat-Gorgani, M.
Effect of polyamines on the structure, thermal stability and 2,2,2-trifluoroethanol-induced aggregation of alpha-chymotrypsin
Int. J. Biol. Macromol.
41
597-604
2007
Bos taurus
Chicon, R.; Lopez-Fandino, R.; Quiros, A.; Belloque, J.
Changes in chymotrypsin hydrolysis of beta-lactoglobulin A induced by high hydrostatic pressure
J. Agric. Food Chem.
54
2333-2341
2006
Bos taurus
Spink, E.; Cosgrove, S.; Rogers, L.; Hewage, C.; Malthouse, J.P.
13C and 1H NMR studies of ionizations and hydrogen bonding in chymotrypsin-glyoxal inhibitor complexes
J. Biol. Chem.
282
7852-7861
2007
Bos taurus
Miao, Q.; Sun, Y.; Wei, T.; Zhao, X.; Zhao, K.; Yan, L.; Zhang, X.; Shu, H.; Yang, F.
Chymotrypsin B cached in rat liver lysosomes and involved in apoptotic regulation through a mitochondrial pathway
J. Biol. Chem.
283
8218-8228
2008
Rattus norvegicus (P07338)
Tubio, G.; Nerli, B.; Pico, G.
Partitioning features of bovine trypsin and alpha-chymotrypsin in polyethyleneglycol-sodium citrate aqueous two-phase systems
J. Chromatogr. B
852
244-249
2007
Bos taurus
Abuin, E.; Lissi, E.; Calderon, C.
Kinetics of N-glutaryl-L-phenylalanine p-nitroanilide hydrolysis catalyzed by alpha-chymotrypsin in aqueous solutions of alkyltrimethylammonium bromides
J. Colloid Interface Sci.
308
573-576
2007
Bos taurus
Hong, J.; Xu, D.; Gong, P.; Sun, H.; Dong, L.; Yao, S.
Covalent binding of alpha-chymotrypsin on the magnetic nanogels covered by amino groups
J. Mol. Catal. B
45
84-90
2007
Bos taurus
-
Spreti, N.; Mancini, M.V.; Germani, R.; Di Profio, P.; Savelli, G.
Substrate effect on alpha-chymotrypsin activity in aqueous solutions of "big-head" ammonium salts
J. Mol. Catal. B
50
1-6
2008
Bos taurus
-
Okamura, M.; Yokoyama, N.; Takabatake, N.; Okubo, K.; Ikehara, Y.; Igarashi, I.
Modification of host erythrocyte membranes by trypsin and chymotrypsin treatments and effects on the in vitro growth of bovine and equine Babesia parasites
J. Parasitol.
93
208-211
2007
Bos taurus
Banerjee, D.; Srivastava, S.K.; Pal, S.K.
Spectroscopic studies on ligand-enzyme interactions: complexation of alpha-chymotrypsin with 4,6-diamidino-2-phenylindole (DAPI)
J. Phys. Chem. B
112
1828-1833
2008
Bos taurus (P00766)
Jelinek, B.; Katona, G.; Fodor, K.; Venekei, I.; Graf, L.
The crystal structure of a trypsin-like mutant chymotrypsin: the role of position 226 in the activity and specificity of S189D chymotrypsin
Protein J.
27
79-87
2008
Rattus norvegicus
Wysocka, M.; Lesner, A.; Legowska, A.; Ja?kiewicz, A.; Miecznikowska, H.; Rolka, K.
Designing of substrates and inhibitors of bovine alpha-chymotrypsin with synthetic phenylalanine analogues in position P(1)
Protein Pept. Lett.
15
260-264
2008
Bos taurus
Lopes, A.R.; Sato, P.M.; Terra, W.R.
Insect chymotrypsins: chloromethyl ketone inactivation and substrate specificity relative to possible coevolutional adaptation of insects and plants
Arch. Insect Biochem. Physiol.
70
188-203
2009
Bos taurus, Tenebrio molitor, Diatraea saccharalis, Periplaneta americana (Q1M0X9), Spodoptera frugiperda (Q86M89), Spodoptera frugiperda
Adriano, W.S.; Mendonca, D.B.; Rodrigues, D.S.; Mammarella, E.J.; Giordano, R.L.
Improving the properties of chitosan as support for the covalent multipoint immobilization of chymotrypsin
Biomacromolecules
9
2170-2179
2008
Bos taurus
Legowska, A.; Debowski, D.; Lesner, A.; Wysocka, M.; Rolka, K.
Introduction of non-natural amino acid residues into the substrate-specific P(1) position of trypsin inhibitor SFTI-1 yields potent chymotrypsin and cathepsin G inhibitors
Bioorg. Med. Chem.
17
3302-3307
2009
Bos taurus
Rezaei-Ghaleh, N.; Zweckstetter, M.; Morshedi, D.; Ebrahim-Habibi, A.; Nemat-Gorgani, M.
Amyloidogenic potential of alpha-chymotrypsin in different conformational states
Biopolymers
91
28-36
2009
Bos taurus (P00766)
Rodriguez-Martinez, J.A.; Sola, R.J.; Castillo, B.; Cintron-Colon, H.R.; Rivera-Rivera, I.; Barletta, G.; Griebenow, K.
Stabilization of alpha-chymotrypsin upon PEGylation correlates with reduced structural dynamics
Biotechnol. Bioeng.
101
1142-1149
2008
Bos taurus
Pham, V.T.; Ewing, E.; Kaplan, H.; Choma, C.; Hefford, M.A.
Glycation improves the thermostability of trypsin and chymotrypsin
Biotechnol. Bioeng.
101
452-459
2008
Bos taurus
Rodriguez-Martinez, J.A.; Rivera-Rivera, I.; Sola, R.J.; Griebenow, K.
Enzymatic activity and thermal stability of PEG-alpha-chymotrypsin conjugates
Biotechnol. Lett.
31
883-887
2009
Bos taurus
Solanki, K.; Gupta, M.N.
Optimising biocatalyst design for obtaining high transesterification activity by alpha-chymotrypsin in non-aqueous media
Chem. Cent. J.
2
2
2008
Bos taurus
Demaneche, S.; Chapel, J.P.; Monrozier, L.J.; Quiquampoix, H.
Dissimilar pH-dependent adsorption features of bovine serum albumin and alpha-chymotrypsin on mica probed by AFM
Colloids Surf. B Biointerfaces
70
226-231
2009
Bos taurus
Zelazko, M.; Chrzanowska, J.; Polanowski, A.
Pancreatic proteolytic enzymes of ostrich purified on immobilized protein inhibitors. Characterization of a new form of chymotrypsin (Chtr1)
Comp. Biochem. Physiol. B
151
102-109
2008
Bos taurus, Struthio camelus
Telang, M.A.; Giri, A.P.; Pyati, P.S.; Gupta, V.S.; Tegeder, M.; Franceschi, V.R.
Winged bean chymotrypsin inhibitors retard growth of Helicoverpa armigera
Gene
431
80-85
2009
Bos taurus
Ju, H.Y.; Too, J.R.; Chang, C.; Shieh, C.J.
Optimal alpha-chymotrypsin-catalyzed synthesis of N-Ac-Phe-Gly-NH(2)
J. Agric. Food Chem.
57
403-408
2009
Bos taurus
Linington, R.G.; Edwards, D.J.; Shuman, C.F.; McPhail, K.L.; Matainaho, T.; Gerwick, W.H.
Symplocamide A, a potent cytotoxin and chymotrypsin inhibitor from the marine Cyanobacterium Symploca sp
J. Nat. Prod.
71
22-27
2008
Homo sapiens
Venkatesu, P.; Lee, M.J.; Lin, H.M.
Osmolyte Counteracts Urea-Induced Denaturation of alpha-Chymotrypsin
J. Phys. Chem. B
113
5327-5338
2009
Bos taurus (P00766)
Banerjee, D.; Pal, S.K.
Conformational dynamics at the active site of alpha-chymotrypsin and enzymatic activity
Langmuir
24
8163-8168
2008
Bos taurus
Ye, X.; Bun Ng, T.
A trypsin-chymotrypsin inhibitor with antiproliferative activity from small glossy black soybeans
Planta Med.
75
550-556
2009
Bos taurus
Cheung, A.H.; Wong, J.H.; Ng, T.B.
Trypsin-chymotrypsin inhibitors from Vigna mungo seeds
Protein Pept. Lett.
16
277-284
2009
Bos taurus
Lesner, A.; Wysocka, M.; Solek, M.; Legowska, A.; Rolka, K.
Low-molecular-weight aldehyde inhibitors of cathepsin g
Protein Pept. Lett.
16
408-410
2009
Bos taurus
Deppe, M.; Risopatron, J.; Sanchez, R.
Trypsin and chymotrypsin are involved in the progesterone-induced acrosome reaction in canine spermatozoa
Reprod. Domest. Anim.
45
453-457
2010
Canis lupus familiaris
Yang, Q.; Sun, L.; Zhang, D.; Qian, J.; Sun, Y.; Ma, L.; Sun, J.; Hu, X.; Tan, W.; Wang, W.; Zhu, C.
Partial characterization of deltamethrin metabolism catalyzed by chymotrypsin
Toxicol. In Vitro
22
1528-1533
2008
Bos taurus
Fricker, S.P.; Mosi, R.M.; Cameron, B.R.; Baird, I.; Zhu, Y.; Anastassov, V.; Cox, J.; Doyle, P.S.; Hansell, E.; Lau, G.; Langille, J.; Olsen, M.; Qin, L.; Skerlj, R.; Wong, R.S.; Santucci, Z.; McKerrow, J.H.
Metal compounds for the treatment of parasitic diseases
J. Inorg. Biochem.
102
1839-1845
2008
Homo sapiens
Bruni, N.; Di Maro, A.; Costantini, S.; Chambery, A.; Facchiano, A.M.; Ficca, A.G.; Parente, A.; Poerio, E.
Redesigning the reactive site loop of the wheat subtilisin/chymotrypsin inhibitor (WSCI) by site-directed mutagenesis. A protein-protein interaction study by affinity chromatography and molecular modeling
Biochimie
91
1112-1122
2009
Bos taurus
Nakamura, H.; Watanabe, M.; Ban, H.S.; Nabeyama, W.; Asai, A.
Synthesis and biological evaluation of boron peptide analogues of Belactosin C as proteasome inhibitors
Bioorg. Med. Chem. Lett.
19
3220-3224
2009
Homo sapiens
Dutta, S.; Basak, A.; Dasgupta, S.
Design and synthesis of enediyne-peptide conjugates and their inhibiting activity against chymotrypsin
Bioorg. Med. Chem.
17
3900-3908
2009
Bos taurus (P00766)
Roy, S.; Dutta, S.K.
Genomic and cDNA cloning, expression, purification, and characterization of chymotrypsin-trypsin inhibitor from winged bean seeds
Biosci. Biotechnol. Biochem.
73
2671-2676
2009
Bos taurus
Cai, J.; Rosenzweig, B.; Hamilton, A.
Inhibition of chymotrypsin by a self-assembled DNA quadruplex functionalized with cyclic peptide binding fragments
Chemistry
15
328-332
2009
synthetic construct
Castillo-Yanez, F.; Pacheco-Aguilar, R.; Lugo-Sanchez, M.; Garcia-Sanchez, G.; Quintero-Reyes, I.
Biochemical characterization of an isoform of chymotrypsin from the viscera of Monterey sardine (Sardinops sagax caerulea), and comparison with bovine chymotrypsin
Food Chem.
112
634-639
2009
Bos taurus, Sardinops caeruleus
Yang, F.; Su, W.; Lu, B.; Wu, T.; Sun, L.; Hara, K.; Cao, M.
Purification and characterization of chymotrypsins from the hepatopancreas of crucian carp (Carassius auratus)
Food Chem.
116
860-866
2009
Bos taurus, Carassius auratus
Abbasi, M.A.; Lodhi, M.A.; Ahmad, V.U.; Choudhary, M.I.
Kinetics studies on the lignan class of natural compounds that inhibits alpha-chymotrypsin
J. Asian Nat. Prod. Res.
11
933-939
2009
synthetic construct
Pietrusewicz, E.; Sienczyk, M.; Oleksyszyn, J.
Novel diphenyl esters of peptidyl alpha-aminoalkylphosphonates as inhibitors of chymotrypsin and subtilisin
J. Enzyme Inhib. Med. Chem.
24
1229-1236
2009
Bos taurus
Gesner-Apter, S.; Carmeli, S.
Protease inhibitors from a water bloom of the cyanobacterium Microcystis aeruginosa
J. Nat. Prod.
72
1429-1436
2009
synthetic construct
Bayindir, Z.S.; Yuksel, N.
Characterization of niosomes prepared with various nonionic surfactants for paclitaxel oral delivery
J. Pharm. Sci.
99
2049-2060
2010
Bos taurus
Raju, S.; Jayalakshmi, S.K.; Sreeramulu, K.
Differential elicitation of proteases and protease inhibitors in two different genotypes of chickpea (Cicer arietinum) by salicylic acid and spermine
J. Plant Physiol.
166
1015-1022
2009
Bos taurus
Lopes, J.L.; Valadares, N.F.; Moraes, D.I.; Rosa, J.C.; Araujo, H.S.; Beltramini, L.M.
Physico-chemical and antifungal properties of protease inhibitors from Acacia plumosa
Phytochemistry
70
871-879
2009
Bos taurus
Lam, S.K.; Ng, T.B.
A dimeric high-molecular-weight chymotrypsin inhibitor with antitumor and HIV-1 reverse transcriptase inhibitory activities from seeds of Acacia confusa
Phytomedicine
17
621-625
2010
Homo sapiens
Lazar, L.M.; Fisher, S.Z.; Moulin, A.G.; Kovalevsky, A.; Novak, W.R.; Langan, P.; Petsko, G.A.; Ringe, D.
Time-of-flight neutron diffraction study of bovine gamma-chymotrypsin at the Protein Crystallography Station
Acta Crystallogr. Sect. F
67
587-590
2011
Bos taurus (P00766)
Cummings, C.; Murata, H.; Koepsel, R.; Russell, A.J.
Dramatically increased pH and temperature stability of chymotrypsin using dual block polymer-based protein engineering
Biomacromolecules
15
763-771
2014
Bos taurus (P00766)
Verma, S.; Ghosh, K.; Verma, R.; Xiang, W.; Li, N.; Zhao, X.
Surface, conformational and catalytic activity approach of alpha-chymotrypsin and trypsin in micellar media
Colloids Surf. A Physicochem. Eng. Asp.
470
188-193
2015
Bos taurus (P00766)
-
Cunha, E.; Passos, M.L.; Pinto, P.C.; Saraiva, M.L.
Improved activity of alpha-chymotrypsin in mixed micelles of cetyltrimethylammonium bromide (CTAB) and ionic liquids: a kinetic study resorting to sequential injection analysis
Colloids Surf. B Biointerfaces
118
172-178
2014
Bos taurus (P00766)
Villalba-Villalba, A.G.; Ramirez-Suarez, J.C.; Pacheco-Aguilar, R.; Valenzuela-Soto, E.M.; Lugo-Sanchez, M.E.; Figueroa-Soto, C.G.
Purification and characterization of chymotrypsin from viscera of vermiculated sailfin catfish, Pterygoplichthys disjunctivus, Weber, 1991
Fish Physiol. Biochem.
39
121-130
2013
Pterygoplichthys disjunctivus
Balti, R.; Bougherra, F.; Bougatef, A.; Hayet, B.; Nedjar-Arroume, N.; Dhulster, P.; Guillochon, D.; Nasri, M.
Chymotrypsin from the hepatopancreas of cuttlefish (Sepia officinalis) with high activity in the hydrolysis of long chain peptide substrates: Purification and biochemical characterisation
Food Chem.
130
475-484
2012
Sepia officinalis
Navarrete-del-Toro, M.A.; Garcia-Carreno, F.L.; Hernandez-Cortes, P.; Molnar, T.; Graf, L.
Biochemical characterisation of chymotrypsin from the midgut gland of yellowleg shrimp, Penaeus californiensis
Food Chem.
173
147-155
2015
Penaeus californiensis (U5KGX4), Penaeus californiensis
Tamaki, F.K.; Padilha, M.H.; Pimentel, A.C.; Ribeiro, A.F.; Terra, W.R.
Properties and secretory mechanism of Musca domestica digestive chymotrypsin and its relation with Drosophila melanogaster homologs
Insect Biochem. Mol. Biol.
42
482-490
2012
Musca domestica
Verma, S.; Ghosh, K.
Activity, stability and kinetic parameters for alpha-chymotrypsin catalysed reactions in AOT/isooctane reverse micelles with nonionic and zwitterionic mixed surfactants
J. Chem. Sci.
125
875-882
2013
Bos taurus (P00766)
-
Paulus, A.; Morhardt, C.; Lehle, N.; Franzreb, M.
Recovery of chymotrypsin using magnetic particles and aqueous micellar two-phase systems: Influence of non-ionic surfactants on enzyme activity
J. Mol. Catal. B
110
165-170
2014
Bos taurus (P00766)
-
Valiullina, Y.; Ermakova, E.; Faizullin, D.; Mirgorodskaya, A.; Zuev, Y.
Structure and properties of complexes of α-chymotrypsin with hydroxyl-containing gemini dicationic surfactants with a spacer moiety of varying length
J. Struct. Chem.
55
1556-1564
2014
Bos taurus (P00766)
-
Verma, S.; Ghosh, K.
Effect of cationic surfactants on the enzymatic activity of alpha-chymotrypsin
Kinet. Catal.
52
6-10
2011
Bos taurus (P00766)
-
Moyano, F.; Setien, E.; Silber, J.J.; Correa, N.M.
Enzymatic hydrolysis of N-benzoyl-L-tyrosine p-nitroanilide by ?-chymotrypsin in DMSO-water/AOT/n-heptane reverse micelles. A unique interfacial effect on the enzymatic activity
Langmuir
29
8245-8254
2013
Bos taurus (P00766)
Perveen, S.; Mustafa, S.; Latif, M.; Iqbal, L.; Usmani, T.; Khan, K.; Voelter, W.
Unsymmetrical 1,3-disubstituted urea derivatives as alpha-chymotrypsin inhibitors
Med. Chem. Res.
23
3585-3592
2014
Bos taurus (P00766)
-
Rather, G.M.; Mukherjee, J.; Halling, P.J.; Gupta, M.N.
Activation of alpha chymotrypsin by three phase partitioning is accompanied by aggregation
PLoS ONE
7
e49241
2012
Bos taurus (P00766)
Spelzini, D.; Farruggia, B.; Pico, G.
Purification of chymotrypsin from pancreas homogenate by adsorption onto non-soluble alginate beads
Process Biochem.
46
801-805
2011
Bos taurus
-
Chen, Q.; Zhang, J.; Zhao, K.; Li, W.; Miao, Q.; Sun, Y.; Zhao, X.; Wei, T.; Yang, F.
Lysosomal chymotrypsin induces mitochondrial fission in apoptotic cells by proteolytic activation of calcineurin
Protein Cell
5
643-647
2014
Homo sapiens
Hicks, P.; Rinker, K.; Baker, J.; Kelly, R.
Homomultimeric protease in the hyperthermophilic bacterium Thermotoga maritima has structural and amino acid sequence homology to bacteriocins in mesophilic bacteria
FEBS Lett.
440
393-398
1998
Thermotoga maritima (Q9WZP2), Thermotoga maritima, Thermotoga maritima DSM 3109 (Q9WZP2)
Shah, D.; Mital, K.
The role of trypsin chymotrypsin in tissue repair
Adv. Ther.
35
31-42
2018
unidentified
Plyushchenko, A.; Borovikova, L.; Pisarev, O.
Proteolytic activity of chymotrypsin immobilized on selenium nanoparticles
Appl. Biochem. Microbiol.
54
375-378
2018
Bos taurus (P00766)
-
Marasini, B.P.; Rahim, F.; Perveen, S.; Karim, A.; Mohammed Khan, K.; Atta-Ur-Rahman, K.; Choudhary, M.I.
Synthesis, structure-activity relationships studies of benzoxazinone derivatives as alpha-chymotrypsin inhibitors
Bioorg. Chem.
70
210-221
2017
Bos taurus (P00766)
Schuabb, V.; Winter, R.; Czeslik, C.
Improved activity of alpha-chymotrypsin on silica particles - A high-pressure stopped-flow study
Biophys. Chem.
218
1-6
2016
Bos taurus (P00766)
Yoshimoto, M.; Yamada, J.; Baba, M.; Walde, P.
Enhanced heat stability of alpha-chymotrypsin through single-enzyme confinement in Attoliter liposomes
ChemBioChem
17
1221-1224
2016
Bos taurus (P00766)
Marquez-Rios, E.; Cota-Arriola, O.; Villalba-Villalba, A.G.; Ezquerra-Brauer, J.M.; Ocano-Higuera, V.M.; Lopez-Corona, B.E.; Torres-Arreola, W.
Chymotrypsin isolation from jumbo squid (Dosidicus gigas) hepatopancreas Partial characterization and effect on muscle collagen
Food Sci. Biotechnol.
25
1011-1016
2016
Dosidicus gigas
Jancso, Z.; Hegyi, E.; Sahin-Toth, M.
Chymotrypsin reduces the severity of secretagogue-induced pancreatitis in mice
Gastroenterology
155
1017-1021
2018
Mus musculus
Vorobev, M.; Kochetkov, K.
Determination of kinetic parameters for casein hydrolysis by chymotrypsin using two ranges of substrate concentration
Int. Dairy J.
61
76-84
2016
Bos taurus (P00766)
-
Asgharzadeh, S.; Shareghi, B.; Farhadian, S.
Experimental and theoretical investigations on the interaction of L-methionine molecules with alpha-chymotrypsin in the aqueous solution using various methods
Int. J. Biol. Macromol.
131
548-556
2019
Bos taurus (P00766)
Catto, C.; Secundo, F.; James, G.; Villa, F.; Cappitelli, F.
alpha-Chymotrypsin Immobilized on a low-density polyethylene surface successfully weakens Escherichia coli biofilm formation
Int. J. Mol. Sci.
19
4003
2018
Escherichia coli, Escherichia coli MG1655
Wang, J.; Zheng, X.; Wang, W.; Guo, H.; Liu, R.; Zong, W.
A study on the interaction between cadmium and alpha-chymotrypsin and the underlying mechanisms
J. Biochem. Mol. Toxicol.
33
e22248
2019
Bos taurus (P00766)
Farhadian, S.; Shareghi, B.; Saboury, A.A.
Exploring the thermal stability and activity of alpha-chymotrypsin in the presence of spermine
J. Biomol. Struct. Dyn.
35
435-448
2017
Bos taurus (P00766)
Patra, A.; Samanta, N.; Das, D.K.; Mitra, R.K.
Enhanced catalytic activity of alpha-chymotrypsin in cationic surfactant solutions the component specificity revisited
J. Phys. Chem. B
121
1457-1465
2017
Bos taurus (P00766)
Bibo-Verdugo, B.; Rojo-Arreola, L.; Navarrete-del-Toro, M.A.; Garcia-Carreno, F.
A chymotrypsin from the digestive tract of California Spiny Lobster, Panulirus interruptus purification and biochemical characterization
Mar. Biotechnol.
17
416-427
2015
Panulirus interruptus
Mazur-Marzec, H.; Fidor, A.; Ceglowska, M.; Wieczerzak, E.; Kropidlowska, M.; Goua, M.; Macaskill, J.; Edwards, C.
Cyanopeptolins with trypsin and chymotrypsin inhibitory activity from the cyanobacterium Nostoc edaphicum CCNP1411
Mar. Drugs
16
E220
2018
Bos taurus (P00766)
Komissarov, I.; Kuchierskaya, A.; Sirotkin, V.
Residual activity of alpha-chymotrypsin in water-1,2-propanediol mixtures
Organic Solvents: Properties Applications and Health Effects
1
73-91
2017
Bos taurus (P00766)
-
Bahamondes, C.; Alvaro, G.; Wilson, L.; Illanes, A.
Effect of enzyme load and catalyst particle size on the diffusional restrictions in reactions of synthesis and hydrolysis catalyzed by alpha-chymotrypsin immobilized into glyoxal-agarose
Process Biochem.
53
172-179
2017
Bos taurus (P00766)
-
De Matteis, L.; Di Renzo, F.; Germani, R.; Goracci, L.; Spreti, N.; Tiecco, M.
alpha-Chymotrypsin superactivity in quaternary ammonium salt solution Kinetic and computational studies
RSC Adv.
6
46202-46211
2016
Bos taurus (P00766)
-
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