Reference on EC 3.4.18.1 - cathepsin X

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Edge, M.; Forder, C.; Hennam, J.; Lee, I.; Tonge, D.; Hardern, I.; Fitton, J.; Eckersley, K.; East, S.; Shufflebotham, A.; Blakey, D.; Slater, A.
Engineered human carboxypeptidase B enzymes that hydrolyse hippuryl-L-glutamic acid: reversed-polarity mutants
Protein Eng.
11
1229-1234
1998
Homo sapiens
Manually annotated by BRENDA team
Afroz, H.; Otto, K.; Mueller, R.; Fuhge, P.
On the specificity of bovine spleen cathepsin B2
Biochim. Biophys. Acta
452
503-509
1976
Bos taurus
Manually annotated by BRENDA team
Ninjoor, V.; Taylor, S.L.; Tappel, A.L.
Purification and characterization of rat liver lysosomal cathepsin B2
Biochim. Biophys. Acta
370
308-321
1974
Rattus norvegicus
Manually annotated by BRENDA team
De Lumen, B.O.; Tappel, A.L.
Histone hydrolase activity of rat liver lysosomal cathepsin B2
Biochim. Biophys. Acta
293
217-225
1973
Rattus norvegicus
Manually annotated by BRENDA team
Distelmaier, P.; Huebner, H.; Otto, K.
Cathepsins B1 and B2 in various organs of the rat
Enzymologia
42
363-375
1972
Rattus norvegicus
Manually annotated by BRENDA team
Otto, K.; Riesenkönig, H.
Improved purification of cathepsin B1 and cathepsin B2
Biochim. Biophys. Acta
379
462-475
1975
Bos taurus
Manually annotated by BRENDA team
Klemencic, I.; Carmona, A.K.; Cezari, M.H.; Juliano, M.A.; Juliano, L.; Guncar, G.; Turk, D.; Krizaj, I.; Turk, V.; Turk, B.
Biochemical characterization of human cathepsin X revealed that the enzyme is an exopeptidase, acting as carboxymonopeptidase or carboxydipeptidase
Eur. J. Biochem.
267
5404-5412
2000
Homo sapiens
Manually annotated by BRENDA team
Guncar, G.; Klemencic, I.; Turk, B.; Turk, V.; Karaoglanovic-Carmona, A.; Juliano, L.; Turk, D.
Crystal structure of cathepsin X: a flip-flop of the ring of His23 allows carboxy-monopeptidase and carboxy-dipeptidase activity of the protease
Structure Fold. Des.
8
305-313
2000
Homo sapiens
Manually annotated by BRENDA team
Devanathan, G.; Turnbull, J.L.; Ziomek, E.; Purisima, E.O.; Menard, R.; Sulea, T.
Carboxy-monopeptidase substrate specificity of human cathepsin X
Biochem. Biophys. Res. Commun.
329
445-452
2005
Homo sapiens, Homo sapiens (Q9UBR2)
Manually annotated by BRENDA team
Kos, J.; Sekirnik, A.; Premzl, A.; Zavasnik Bergant, V.; Langerholc, T.; Turk, B.; Werle, B.; Golouh, R.; Repnik, U.; Jeras, M.; Turk, V.
Carboxypeptidases cathepsins X and B display distinct protein profile in human cells and tissues
Exp. Cell Res.
306
103-113
2005
Homo sapiens
Manually annotated by BRENDA team
Obermajer, N.; Premzl, A.; Zavasnik Bergant, T.; Turk, B.; Kos, J.
Carboxypeptidase cathepsin X mediates beta(2)-integrin-dependent adhesion of differentiated U-937 cells
Exp. Cell Res.
312
2515-2527
2006
Homo sapiens
Manually annotated by BRENDA team
Nägler, D.K.; Lechner, A.M.; Oettl, A.; Kozaczynska, K.; Scheuber, H.P.; Gippner-Steppert, C.; Bogner, V.; Biberthaler, P.; Jochum, M.
An enzyme-linked immunosorbent assay for human cathepsin X, a potential new inflammatory marker
J. Immunol. Methods
308
241-250
2006
Homo sapiens
Manually annotated by BRENDA team
Krueger, S.; Kalinski, T.; Hundertmark, T.; Wex, T.; Kuster, D.; Peitz, U.; Ebert, M.; Nagler, D.K.; Kellner, U.; Malfertheiner, P.; Naumann, M.; Rocken, C.; Roessner, A.
Up-regulation of cathepsin X in Helicobacter pylori gastritis and gastric cancer
J. Pathol.
207
32-42
2005
Homo sapiens
Manually annotated by BRENDA team
Vasiljeva, O.; Papazoglou, A.; Krueger, A.; Brodoefel, H.; Korovin, M.; Deussing, J.; Augustin, N.; Nielsen, B.S.; Almholt, K.; Bogyo, M.; Peters, C.; Reinheckel, T.
Tumor cell-derived and macrophage-derived cathepsin B promotes progression and lung metastasis of mammary cancer
Cancer Res.
66
5242-5250
2006
Mus musculus
Manually annotated by BRENDA team
Cooke, G.S.; Campbell, S.J.; Bennett, S.; Lienhardt, C.; McAdam, K.P.; Sow, O.; Gustafson, P.; Mwangulu, F.; van Helden, P.; Fine, P.; Hoal, E.G.; Hill, A.V.
Mapping of a novel susceptibility locus suggests a role for MC3R and CTSZ in human tuberculosis
Am. J. Respir. Crit. Care Med.
178
203-207
2008
Homo sapiens, Homo sapiens (Q9UBR2)
Manually annotated by BRENDA team
Nyfeler, B.; Hauri, H.P.
Visualization of protein interactions inside the secretory pathway
Biochem. Soc. Trans.
35
970-973
2007
Homo sapiens (Q9UBR2)
Manually annotated by BRENDA team
Bettegowda, A.; Patel, O.V.; Lee, K.B.; Park, K.E.; Salem, M.; Yao, J.; Ireland, J.J.; Smith, G.W.
Identification of novel bovine cumulus cell molecular markers predictive of oocyte competence: functional and diagnostic implications
Biol. Reprod.
79
301-309
2008
Bos taurus (P05689)
Manually annotated by BRENDA team
Kao, C.M.; Huang, F.L.
Cloning and expression of carp cathepsin Z: Possible involvement in yolk metabolism
Comp. Biochem. Physiol. B
149
541-551
2008
Cyprinus carpio, Cyprinus carpio (Q58HG7)
Manually annotated by BRENDA team
Wendt, W.; Zhu, X.R.; Luebbert, H.; Stichel, C.C.
Differential expression of cathepsin X in aging and pathological central nervous system of mice
Exp. Neurol.
204
525-540
2007
Homo sapiens, Mus musculus
Manually annotated by BRENDA team
Obermajer, N.; Repnik, U.; Jevnikar, Z.; Turk, B.; Kreft, M.; Kos, J.
Cysteine protease cathepsin X modulates immune response via activation of beta2 integrins
Immunology
124
76-88
2008
Homo sapiens
Manually annotated by BRENDA team
Lechner, A.M.; Assfalg-Machleidt, I.; Zahler, S.; Stoeckelhuber, M.; Machleidt, W.; Jochum, M.; Naegler, D.K.
RGD-dependent binding of procathepsin X to integrin alphavbeta3 mediates cell-adhesive properties
J. Biol. Chem.
281
39588-39597
2006
Homo sapiens, Homo sapiens (Q9UBR2)
Manually annotated by BRENDA team
Nyfeler, B.; Zhang, B.; Ginsburg, D.; Kaufman, R.J.; Hauri, H.P.
Cargo selectivity of the ERGIC-53/MCFD2 transport receptor complex
Traffic
7
1473-1481
2006
Homo sapiens (Q9UBR2)
Manually annotated by BRENDA team
Ahn, S.J.; Kim, N.Y.; Jeon, S.J.; Sung, J.H.; Je, J.E.; Seo, J.S.; Kim, M.S.; Kim, J.K.; Chung, J.K.; Lee, H.H.
Molecular cloning, tissue distribution and enzymatic characterization of cathepsin X from olive flounder (Paralichthys olivaceus)
Comp. Biochem. Physiol. B
151
203-212
2008
Paralichthys olivaceus, Paralichthys olivaceus (Q58HF4)
Manually annotated by BRENDA team
Krueger, S.; Kuester, D.; Bernhardt, A.; Wex, T.; Roessner, A.
Regulation of cathepsin X overexpression in H. pylori-infected gastric epithelial cells and macrophages
J. Pathol.
217
581-588
2009
Homo sapiens
Manually annotated by BRENDA team
Leichsenring, A.; Baecker, I.; Wendt, W.; Andriske, M.; Schmitz, B.; Stichel, C.C.; Luebbert, H.
Differential expression of cathepsin S and X in the spinal cord of a rat neuropathic pain model
BMC Neurosci.
9
80
2008
Rattus norvegicus
Manually annotated by BRENDA team
Kos, J.; Jevnikar, Z.; Obermajer, N.
The role of cathepsin X in cell signaling
Cell Adh. Migr.
3
164-166
2009
Homo sapiens, Homo sapiens (Q9UBR2)
Manually annotated by BRENDA team
Obermajer, N.; Jevnikar, Z.; Doljak, B.; Sadaghiani, A.M.; Bogyo, M.; Kos, J.
Cathepsin X-mediated beta2 integrin activation results in nanotube outgrowth
Cell. Mol. Life Sci.
66
1126-1134
2009
Homo sapiens (Q9UBR2)
Manually annotated by BRENDA team
Obermajer, N.; Magister, S.; Kopitar, A.N.; Tepes, B.; Ihan, A.; Kos, J.
Cathepsin X prevents an effective immune response against Helicobacter pylori infection
Eur. J. Cell Biol.
88
461-471
2009
Homo sapiens (Q9UBR2)
Manually annotated by BRENDA team
Jevnikar, Z.; Obermajer, N.; Pecar-Fonovi?, U.; Karaoglanovic-Carmona, A.; Kos, J.
Cathepsin X cleaves the beta2 cytoplasmic tail of LFA-1 inducing the intermediate affinity form of LFA-1 and alpha-actinin-1 binding
Eur. J. Immunol.
39
3217-3227
2009
Homo sapiens
Manually annotated by BRENDA team
Staudt, N.D.; Aicher, W.K.; Kalbacher, H.; Stevanovic, S.; Carmona, A.K.; Bogyo, M.; Klein, G.
Cathepsin X is secreted by human osteoblasts, digests CXCL-12 and impairs adhesion of hematopoietic stem and progenitor cells to osteoblasts
Haematologica
95
1452-1460
2010
Homo sapiens, Homo sapiens (Q9UBR2)
Manually annotated by BRENDA team
Naegler, D.K.; Kraus, S.; Feierler, J.; Mentele, R.; Lottspeich, F.; Jochum, M.; Faussner, A.
A cysteine-type carboxypeptidase, cathepsin X, generates peptide receptor agonists
Int. Immunopharmacol.
10
134-139
2010
Homo sapiens
Manually annotated by BRENDA team
Obermajer, N.; Doljak, B.; Jamnik, P.; Fonovic, U.P.; Kos, J.
Cathepsin X cleaves the C-terminal dipeptide of alpha- and gamma-enolase and impairs survival and neuritogenesis of neuronal cells
Int. J. Biochem. Cell Biol.
41
1685-1696
2009
Homo sapiens
Manually annotated by BRENDA team
Sevenich, L.; Schurigt, U.; Sachse, K.; Gajda, M.; Werner, F.; Mueller, S.; Vasiljeva, O.; Schwinde, A.; Klemm, N.; Deussing, J.; Peters, C.; Reinheckel, T.
Synergistic antitumor effects of combined cathepsin B and cathepsin Z deficiencies on breast cancer progression and metastasis in mice
Proc. Natl. Acad. Sci. USA
107
2497-2502
2010
Mus musculus
Manually annotated by BRENDA team
Bak, H.J.; Kim, M.S.; Kim, N.Y.; Go, H.J.; Han, J.W.; In Jo, H.; Ahn, S.J.; Park, N.G.; Chung, J.K.; Lee, H.H.
Molecular cloning, expression, and enzymatic analysis of cathepsin X from starfish (Asterina pectinifera)
Appl. Biochem. Biotechnol.
169
847-861
2013
Patiria pectinifera (G1JRK2)
Manually annotated by BRENDA team
Chantree, P.; Wanichanon, C.; Phatsara, M.; Meemon, K.; Sobhon, P.
Characterization and expression of cathepsin B2 in Fasciola gigantica
Exp. Parasitol.
132
249-256
2012
Fasciola gigantica
Manually annotated by BRENDA team
Bhutani, N.; Piccirillo, R.; Hourez, R.; Venkatraman, P.; Goldberg, A.L.
Cathepsins L and Z are critical in degrading polyglutamine-containing proteins within lysosomes
J. Biol. Chem.
287
17471-17482
2012
Mus musculus
Manually annotated by BRENDA team
Pislar, A.H.; Zidar, N.; Kikelj, D.; Kos, J.
Cathepsin X promotes 6-hydroxydopamine-induced apoptosis of PC12 and SH-SY5Y cells
Neuropharmacology
82
121-131
2014
Rattus norvegicus
Manually annotated by BRENDA team