Disease on EC 3.4.18.1 - cathepsin X

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DISEASE
TITLE OF PUBLICATION
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Adenocarcinoma
Up-regulation of cathepsin X in prostate cancer and prostatic intraepithelial neoplasia.
Alagille Syndrome
Increased expression and altered localization of cathepsin Z are associated with progression to jaundice stage in primary biliary cholangitis.
Alzheimer Disease
Diverse Protein Profiles in CNS Myeloid Cells and CNS Tissue From Lipopolysaccharide- and Vehicle-Injected APPSWE/PS1?E9 Transgenic Mice Implicate Cathepsin Z in Alzheimer's Disease.
Neuroprotective role of ?-enolase in microglia in a mouse model of Alzheimer's disease is regulated by cathepsin X.
Bone Diseases, Metabolic
Cathepsin Z as a novel potential biomarker for osteoporosis.
Breast Neoplasms
Synergistic antitumor effects of combined cathepsin B and cathepsin Z deficiencies on breast cancer progression and metastasis in mice.
Carcinogenesis
Cathepsin proteases promote angiogenic sprouting and laser-induced choroidal neovascularisation in mice.
IGF-I receptor phosphorylation is impaired in cathepsin X-deficient prostate cancer cells.
Up-regulation of cathepsin X in Helicobacter pylori gastritis and gastric cancer.
Up-regulation of cathepsin X in prostate cancer and prostatic intraepithelial neoplasia.
Carcinoma
Up-regulation of cathepsin X in Helicobacter pylori gastritis and gastric cancer.
Up-regulation of cathepsin X in prostate cancer and prostatic intraepithelial neoplasia.
Carcinoma, Hepatocellular
Overexpression of cathepsin Z contributes to tumor metastasis by inducing epithelial-mesenchymal transition in hepatocellular carcinoma.
cathepsin x deficiency
Acid carboxypeptidase deficiency in galactosialidosis.
Cellular senescence induced by cathepsin X downregulation.
IGF-I receptor phosphorylation is impaired in cathepsin X-deficient prostate cancer cells.
Synergistic antitumor effects of combined cathepsin B and cathepsin Z deficiencies on breast cancer progression and metastasis in mice.
Cholangitis
Increased expression and altered localization of cathepsin Z are associated with progression to jaundice stage in primary biliary cholangitis.
Colorectal Neoplasms
Cathepsin X in serum from patients with colorectal cancer: relation to prognosis.
Characterization of cathepsin X in colorectal cancer development and progression.
KMT2A histone methyltransferase contributes to colorectal cancer development by promoting cathepsin Z transcriptional activation.
Prognostic and predictive value of cathepsin X in serum from colorectal cancer patients.
Encephalitis
Development of Activity-Based Probes for Cathepsin X.
Encephalomyelitis
A role for cathepsin Z in neuroinflammation provides mechanistic support for an epigenetic risk factor in multiple sclerosis.
Encephalomyelitis, Autoimmune, Experimental
A role for cathepsin Z in neuroinflammation provides mechanistic support for an epigenetic risk factor in multiple sclerosis.
Gallbladder Neoplasms
Identification of prosaposin and transgelin as potential biomarkers for gallbladder cancer using quantitative proteomics.
Gastritis
Cathepsin X prevents an effective immune response against Helicobacter pylori infection.
Up-regulation of cathepsin X in Helicobacter pylori gastritis and gastric cancer.
Glioma
Localization patterns of cathepsins K and X and their predictive value in glioblastoma.
Hepatitis
Effect on vitamin A on the development of galactosamine-induced hepatitis in rats.
[Distribution and activity of lysosomal protein catabolic-enzymes of rat liver in galactosamine hepatitis: catepsin D, cathepsin A and acid carboxypeptidase]
Infections
Cathepsin X prevents an effective immune response against Helicobacter pylori infection.
Cathepsin X-deficient gastric epithelial cells in co-culture with macrophages: characterization of cytokine response and migration capability after helicobacter pylori infection.
Cathepsins K, L, B, X and W are differentially expressed in normal and chronically inflamed gastric mucosa.
Generation of a single-chain variable fragment phage display antibody library from naïve mice panned against Fasciola hepatica antigens.
Up-regulation of cathepsin X in Helicobacter pylori gastritis and gastric cancer.
Vaccine potential of recombinant cathepsin B against Fasciola gigantica.
Inflammatory Breast Neoplasms
Cathepsin B, cathepsin H, cathepsin X and cystatin C in sera of patients with early-stage and inflammatory breast cancer.
Intestinal Volvulus
The Caenorhabditis elegans cathepsin Z-like cysteine protease, Ce-CPZ-1, has a multifunctional role during the worms' development.
Liver Cirrhosis, Biliary
Increased expression and altered localization of cathepsin Z are associated with progression to jaundice stage in primary biliary cholangitis.
Liver Diseases
Increased expression and altered localization of cathepsin Z are associated with progression to jaundice stage in primary biliary cholangitis.
Lung Neoplasms
Carboxypeptidases cathepsins X and B display distinct protein profile in human cells and tissues.
Multiple Sclerosis
A role for cathepsin Z in neuroinflammation provides mechanistic support for an epigenetic risk factor in multiple sclerosis.
Neoplasm Metastasis
Carboxypeptidases cathepsins X and B display distinct protein profile in human cells and tissues.
Overexpression of cathepsin Z contributes to tumor metastasis by inducing epithelial-mesenchymal transition in hepatocellular carcinoma.
Synergistic antitumor effects of combined cathepsin B and cathepsin Z deficiencies on breast cancer progression and metastasis in mice.
Neoplasms
Carboxypeptidases cathepsins X and B display distinct protein profile in human cells and tissues.
Cathepsin proteases promote angiogenic sprouting and laser-induced choroidal neovascularisation in mice.
Cathepsin X Cleaves Profilin 1 C-Terminal Tyr139 and Influences Clathrin-Mediated Endocytosis.
Cathepsin X in serum from patients with colorectal cancer: relation to prognosis.
Cathepsin Z, a novel human cysteine proteinase with a short propeptide domain and a unique chromosomal location.
Cellular senescence induced by cathepsin X downregulation.
Characterization of cathepsin X in colorectal cancer development and progression.
Cloning and complete coding sequence of a novel human cathepsin expressed in giant cells of osteoclastomas.
Development of Activity-Based Probes for Cathepsin X.
Distinct functions of macrophage-derived and cancer cell-derived cathepsin Z combine to promote tumor malignancy via interactions with the extracellular matrix.
Dysregulation of apoptotic signaling pathways by interaction of RPLP0 and cathepsin X/Z in gastric cancer.
Identification and characterization of the novel reversible and selective cathepsin X inhibitors.
IGF-I receptor phosphorylation is impaired in cathepsin X-deficient prostate cancer cells.
Inhibition of cathepsin X reduces the strength of microglial-mediated neuroinflammation.
Intracellular signaling by cathepsin X: Molecular mechanisms and diagnostic and therapeutic opportunities in cancer.
Overexpression of cathepsin Z contributes to tumor metastasis by inducing epithelial-mesenchymal transition in hepatocellular carcinoma.
Physical activity is associated with a large number of cardiovascular-specific proteins: Cross-sectional analyses in two independent cohorts.
Profilin 1 as a target for cathepsin X activity in tumor cells.
Synergistic antitumor effects of combined cathepsin B and cathepsin Z deficiencies on breast cancer progression and metastasis in mice.
Tumor cell-derived and macrophage-derived cathepsin B promotes progression and lung metastasis of mammary cancer.
Up-regulation of cathepsin X in Helicobacter pylori gastritis and gastric cancer.
Up-regulation of cathepsin X in prostate cancer and prostatic intraepithelial neoplasia.
Neuroblastoma
Cathepsin X promotes 6-hydroxydopamine-induced apoptosis of PC12 and SH-SY5Y cells.
Neurodegenerative Diseases
Cathepsin X in serum from patients with colorectal cancer: relation to prognosis.
Cathepsin X promotes 6-hydroxydopamine-induced apoptosis of PC12 and SH-SY5Y cells.
Identification and characterization of the novel reversible and selective cathepsin X inhibitors.
Neuroendocrine Tumors
Distinct functions of macrophage-derived and cancer cell-derived cathepsin Z combine to promote tumor malignancy via interactions with the extracellular matrix.
Osteoporosis
Cathepsin Z as a novel potential biomarker for osteoporosis.
Pancreatic Neoplasms
S100P-Binding Protein, S100PBP, Mediates Adhesion through Regulation of Cathepsin Z in Pancreatic Cancer Cells.
Parkinson Disease
Cathepsin X promotes 6-hydroxydopamine-induced apoptosis of PC12 and SH-SY5Y cells.
Upregulation of Cysteine Protease Cathepsin X in the 6-Hydroxydopamine Model of Parkinson's Disease.
Pheochromocytoma
Cathepsin X promotes 6-hydroxydopamine-induced apoptosis of PC12 and SH-SY5Y cells.
Prostatic Intraepithelial Neoplasia
Up-regulation of cathepsin X in prostate cancer and prostatic intraepithelial neoplasia.
Prostatic Neoplasms
Profilin 1 as a target for cathepsin X activity in tumor cells.
Up-regulation of cathepsin X in prostate cancer and prostatic intraepithelial neoplasia.
Sepsis
Increased expression and altered localization of cathepsin Z are associated with progression to jaundice stage in primary biliary cholangitis.
Stomach Neoplasms
Cathepsin X-deficient gastric epithelial cells in co-culture with macrophages: characterization of cytokine response and migration capability after helicobacter pylori infection.
Regulation of cathepsin X overexpression in H. pylori-infected gastric epithelial cells and macrophages.
Up-regulation of cathepsin X in Helicobacter pylori gastritis and gastric cancer.
Tuberculosis
Genetic susceptibility to tuberculosis associated with cathepsin Z haplotype in a Ugandan household contact study.
Mapping of a novel susceptibility locus suggests a role for MC3R and CTSZ in human tuberculosis.
Polymorphisms in MC3R promoter and CTSZ 3'UTR are associated with tuberculosis susceptibility.
Tuberculosis, Pulmonary
Association of CTSZ rs34069356 and MC3R rs6127698 gene polymorphisms with pulmonary tuberculosis.