Reference on EC 3.4.17.2 - carboxypeptidase B
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Sakharov, D.V.; Plow, E.F.; Rijken, D.C.
On the mechanism of the antifibrinolytic activity of plasma carboxypeptidase B
J. Biol. Chem.
272
14477-14482
1997
Homo sapiens
Eaton, D.L.; Malloy, B.E.; Tsai, S.P.; Henzel, W.; Drayna, D.
Isolation, molecular cloning, and partial characterization of a novel carboxypeptidase B from human plasma
J. Biol. Chem.
266
21833-21838
1991
Homo sapiens
Hajjou, M.; Smine, A.; Guerard, F.; le Gal, Y.
Purification and some properties of a carboxypeptidase B from dogfish Scyliorhinus canicula
Comp. Biochem. Physiol. B
110
791-798
1995
Scyliorhinus canicula
-
Gates, B.J.; Travis, J.
Purification and characterization of carboxypeptidases A and B from the white shrimp (Penaeus setiferus)
Biochemistry
12
1867-1874
1973
Penaeus setiferus
Reeck, G.R.; Walsh, K.A.; Neurath, H.
Isolation and characterization of carboxypeptidases A and B from activated pancreatic juice
Biochemistry
10
4690-4698
1971
Bos taurus
Clauser, E.; Gardell, S.J.; Craik, C.S.; MacDonald, R.J.; Rutter, W.J.
Structural characterization of the rat carboxypeptidase A1 and B genes. Comparative analysis of the rat carboxypeptidase gene family
J. Biol. Chem.
263
17837-17845
1988
Rattus norvegicus
Sokolovsky, M.
Affinity chromatography of carboxypeptidase B
Methods Enzymol.
34
411-414
1974
Bos taurus
Folk, J.E.
Carboxypeptidase B (porcine pancreas)
Methods Enzymol.
19
504-508
1970
Bos taurus
-
Folk, J.E.; Piez, K.A.; Carroll, W.R.; Gladner, J.A.
Carboxypeptidase B
J. Biol. Chem.
235
2272-2277
1960
Sus scrofa
Wintersberger, E.; Cox, D.J.; Neurath, H.
Bovine pancreatic procarboxypeptidase B. I. Isolation, properties, and activation
Biochemistry
1
1069-1078
1962
Bos taurus
Prahl, J.W.; Neurath, H.
Pancreatic enzymes of the spiny pacific dogfish. II. Procarboxypeptidase B and carboxypeptidase B
Biochemistry
5
4137-4145
1966
Squalus acanthias
-
Geokas, M.C.; Largman, C.; Brodrick, J.W.; Raeburn, S.; Rinderknecht, H.
Human pancreatic carboxypeptidase B. I. Isolation, purification, and characterization of fraction II
Biochim. Biophys. Acta
391
396-402
1975
Homo sapiens
Brodrick, J.W.; Geokas, M.C.; Largman, C.
Human carboxypeptidase B. II. Purification of the enzyme from pancreatic tissue and comparison with the enzymes present in pancreatic secretion
Biochim. Biophys. Acta
452
468-481
1976
Homo sapiens
Marinkovic, D.V.; Marinkovic, J.N.; Erds, E.G.; Robinson, C.J.G.
Purification of carboxypeptidase B from human pancreas
Biochem. J.
163
253-260
1977
Homo sapiens
Alter, G.M.M.; Leussing, D.L.; Neurath, H.; Vallee, B.L.
Kinetic properties of carboxypeptidase B in solutions and crystals
Biochemistry
16
3663-3668
1977
Bos taurus
Prins, R.A.; van Rheenen, D.L.; van't Klooster, A.T.
Characterization of microbial proteolytic enzymes in the rumen
Antonie van Leeuwenhoek
49
585-595
1983
rumen bacterium
Bown, D.P.; Wilkinson, H.S.; Gatehouse, J.A.
Midgut carboxypeptidase from Helicoverpa armigera (Lepidoptera: Noctuidae) larvae: enzyme characterisation, cDNA cloning and expression
Insect Biochem. Mol. Biol.
28
739-749
1998
Helicoverpa armigera
Sdi, P.; Dala, E.; Szajani, B.
Preparation, characterization, and application of a novel immobilized carboxypeptidase B
Appl. Biochem. Biotechnol.
22
31-43
1989
Sus scrofa
Hass, G.M.; Derr, J.E.; Makus, D.J.; Ryan, C.A.
Purification and characterization of the carboxypeptidase isoinhibitors from potatoes
Plant Physiol.
64
1022-1028
1979
Bos taurus
Sasaki, I.; Gotoh, H.; Yamamoto, R.; Hasegawa, H.; Yamashita, J.; Horio, T.
Hydrophobic-ionic chromatography. Its application to purification of porcine pancreas enzymes
J. Biochem.
86
1537-1548
1979
Sus scrofa
Ferrell, R.E.; Camacho, Z.; Kitto, G.B.
Purification of a carboxypeptidase B-like enzyme from the starfish Dermasterias imbricata
Biochim. Biophys. Acta
386
260-269
1975
Dermasterias imbricata
Neurath, H.
Carboxypeptidase A and B
The Enzymes, 2nd Ed. (Boyer, P. D. , Lardy, H. , Myrbck, K. , eds. )
4
11-36
1960
Bos taurus
-
Reeck, G.R.; Neurath, H.
Isolation and characterization of pancreatic procarboxypeptidase B and carboxypeptidase B of the African lungfish
Biochemistry
11
3947-3955
1972
Protopterus aethiopicus
Valnickova, Z.; Thogersen, I.B.; Christensen, S.; Chu, C.T.; Pizzo, S.V.; Enghild, J.J.
Activated human plasma carboxypeptidase B is retained in the blood by binding to alpha2-macroglobulin and pregnancy zone protein
J. Biol. Chem.
371
12937-12943
1996
Homo sapiens
Marquez-Mendez, M.
Purification of carboxypeptidase B by metal chelation affinity chromatography
J. Biochem. Biophys. Methods
24
51-61
1992
Nephrops norvegicus
Bradley, G.; Naude, R.J.; Muramoto, K.; Yamauchi, F.; Oelofsen, W.
Ostrich (Struthio camelus) carboxypeptidase B: purification, kinetic properties and characterization of the pancreatic enzyme
Int. J. Biochem. Cell Biol.
28
521-529
1996
Struthio camelus, Sus scrofa
Ortego, F.; Novillo, C.; Castanera, P.
Characterization and distribution of digestive proteases of the stalk corn borer, Sesamia nonagrioides Lef. (Lepidoptera: noctuidae)
Arch. Insect Biochem. Physiol.
32
163-180
1996
Sesamia nonagrioides, Sesamia nonagrioides Lef.
-
Edge, M.; Forder, C.; Hennam, J.; Lee, I.; Tonge, D.; Hardern, I.; Fitton, J.; Eckersley, K.; East, S.; Shufflebotham, A.; Blakey, D.; Slater, A.
Engineered human carboxypeptidase B enzymes that hydrolyse hippuryl-L-glutamic acid: reversed-polarity mutants
Protein Eng.
11
1229-1234
1998
Homo sapiens
Mao, S.S.; Colussi, D.; Bailey, C.M.; Bosserman, M.; Burlein, C.; Gardell, S.J.; Carroll, S.S.
Electrochemiluminescence assay for basic carboxypeptidases: inhibition of basic carboxypeptidases and activation of thrombin-activatable fibrinolysis inhibitor
Anal. Biochem.
319
159-170
2003
Homo sapiens
Kishimura, H.; Hayashi, K.
Isolation and characteristics of carboxypeptidase B from the pyloric ceca of the starfish Asterias amurensis
Comp. Biochem. Physiol. B
133
183-189
2002
Asterias amurensis
Matsumoto, A.; Motozaki, K.; Seki, T.; Sasaki, R.; Kawabe, T.
Expression of human brain carboxypeptidase B, a possible cleaving enzyme for beta-amyloid precursor protein, in peripheral fluids
Neurosci. Res.
39
313-317
2001
Homo sapiens
Ladisch, M.R.; Kohlmann, K.L.
Recombinant human insulin
Biotechnol. Prog.
8
469-478
1992
Sus scrofa
Adler, M.; Bryant, J.; Buckman, B.; Islam, I.; Larsen, B.; Finster, S.; Kent, L.; May, K.; Mohan, R.; Yuan, S.; Whitlow, M.
Crystal structures of potent thiol-based inhibitors bound to carboxypeptidase B
Biochemistry
44
9339-9347
2005
Sus scrofa (P09955), Sus scrofa
Kishimura, H.; Hayashi, K.; Ando, S.
Characteristics of carboxypeptidase B from pyloric ceca of the starfish Asterina pectinifera
Food Chem.
95
264-269
2005
Patiria pectinifera
-
Aviles, F.X.; Vendrell, J.
Carboxypeptidase B
Handbook of Proteolytic Enzymes (Barrett, J. ; Rawlings, N. D. ; Woessner, J. F. , eds. ) Academic Press
2
831-833
2004
Bos taurus, Homo sapiens, Rattus norvegicus, Sus scrofa
-
Wang, P.; Li, G.; Kain, W.
Characterization and cDNA cloning of midgut carboxypeptidases from Trichoplusia ni
Insect Biochem. Mol. Biol.
34
831-843
2004
Trichoplusia ni
Bayes, A.; de la Vega, M.R.; Vendrell, J.; Aviles, F.X.; Jongsma, M.A.; Beekwilder, J.
Response of the digestive system of Helicoverpa zea to ingestion of potato carboxypeptidase inhibitor and characterization of an uninhibited carboxypeptidase B
Insect Biochem. Mol. Biol.
36
654-664
2006
Helicoverpa zea (Q3T905), Helicoverpa zea
Lavazec, C.; Bonnet, S.; Thiery, I.; Boisson, B.; Bourgouin, C.
cpbAg1 encodes an active carboxypeptidase B expressed in the midgut of Anopheles gambiae
Insect Mol. Biol.
14
163-174
2005
Anopheles gambiae
Arolas, J.L.; Lorenzo, J.; Rovira, A.; Castella, J.; Aviles, F.X.; Sommerhoff, C.P.
A carboxypeptidase inhibitor from the tick Rhipicephalus bursa: isolation, cDNA cloning, recombinant expression, and characterization
J. Biol. Chem.
280
3441-3448
2005
Homo sapiens
Arolas, J.L.; Popowicz, G.M.; Lorenzo, J.; Sommerhoff, C.P.; Huber, R.; Aviles, F.X.; Holak, T.A.
The three-dimensional structures of tick carboxypeptidase inhibitor in complex with A/B carboxypeptidases reveal a novel double-headed binding mode
J. Mol. Biol.
350
489-498
2005
Homo sapiens (P15086), Homo sapiens
Borgstroem, A.; Regner, S.
Active carboxypeptidase B is present in free form in serum from patients with acute pancreatitis
Pancreatology
5
530-536
2005
Homo sapiens
Higuchi, T.; Nakamura, T.; Kakutani, H.; Ishii, H.
Thrombomodulin suppresses invasiveness of HT1080 tumor cells by reducing plasminogen activation on the cell surface through activation of thrombin-activatable fibrinolysis inhibitor
Biol. Pharm. Bull.
32
179-185
2009
Homo sapiens
Luo, X.; Bathgate, R.A.; Zhang, W.J.; Liu, Y.L.; Shao, X.X.; Wade, J.D.; Guo, Z.Y.
Design and recombinant expression of insulin-like peptide 5 precursors and the preparation of mature human INSL5
Amino Acids
39
1343-1352
2010
Homo sapiens
Sharif, S.A.; Du, X.; Myles, T.; Song, J.J.; Price, E.; Lee, D.M.; Goodman, S.B.; Nagashima, M.; Morser, J.; Robinson, W.H.; Leung, L.L.
Thrombin-activatable carboxypeptidase B cleavage of osteopontin regulates neutrophil survival and synoviocyte binding in rheumatoid arthritis
Arthritis Rheum.
60
2902-2912
2009
Homo sapiens
Fernandez, D.; Pallares, I.; Vendrell, J.; Aviles, F.X.
Progress in metallocarboxypeptidases and their small molecular weight inhibitors
Biochimie
92
484-500
2010
Sus scrofa (P09955)
Fernandez, D.; Torres, E.; Aviles, F.X.; Ortuno, R.M.; Vendrell, J.
Cyclobutane-containing peptides: evaluation as novel metallocarboxypeptidase inhibitors and modelling of their mode of action
Bioorg. Med. Chem.
17
3824-3828
2009
Homo sapiens
Jiang, L.P.; Zou, C.; Yuan, X.; Luo, W.; Wen, Y.; Chen, Y.
N-terminal modification increases the stability of the recombinant human endostatin in vitro
Biotechnol. Appl. Biochem.
54
113-120
2009
Homo sapiens
Son, Y.J.; Kim, C.K.; Kim, Y.B.; Kweon, D.H.; Park, Y.C.; Seo, J.H.
Effects of citraconylation on enzymatic modification of human proinsulin using trypsin and carboxypeptidase B
Biotechnol. Prog.
25
1064-1070
2009
Sus scrofa
Fernandez, D.; Aviles, F.X.; Vendrell, J.
A new type of five-membered heterocyclic inhibitors of basic metallocarboxypeptidases
Eur. J. Med. Chem.
44
3266-3271
2009
Helicoverpa zea, Homo sapiens
Luo, X.; Bathgate, R.A.; Liu, Y.L.; Shao, X.X.; Wade, J.D.; Guo, Z.Y.
Recombinant expression of an insulin-like peptide 3 (INSL3) precursor and its enzymatic conversion to mature human INSL3
FEBS J.
276
5203-5211
2009
Sus scrofa
Chatterjee, S.; Ehrenshaft, M.; Bhattacharjee, S.; Deterding, L.; Bonini, M.; Corbett, J.; Kadiiska, M.; Tomer, K.; Mason, R.
Immuno-spin trapping of a post-translational carboxypeptidase B1 radical formed by a dual role of xanthine oxidase and endothelial nitric oxide synthase in acute septic mice
Free Radic. Biol. Med.
46
454-461
2009
Mus musculus
Rider, S.A.; Davies, S.J.; Jha, A.N.; Clough, R.; Sweetman, J.W.
Bioavailability of co-supplemented organic and inorganic zinc and selenium sources in a white fishmeal-based rainbow trout (Oncorhynchus mykiss) diet
J. Anim. Physiol. Anim. Nutr. (Berl.)
94
99-110
2010
Oncorhynchus mykiss
Chatterjee, S.; Lardinois, O.; Bonini, M.G.; Bhattacharjee, S.; Stadler, K.; Corbett, J.; Deterding, L.J.; Tomer, K.B.; Kadiiska, M.; Mason, R.P.
Site-specific carboxypeptidase B1 tyrosine nitration and pathophysiological implications following its physical association with nitric oxide synthase-3 in experimental sepsis
J. Immunol.
183
4055-4066
2009
Mus musculus, Sus scrofa
Toth, S.I.; Smith, L.A.; Ahmed, S.A.
Extreme sensitivity of botulinum neurotoxin domains towards mild agitation
J. Pharm. Sci.
98
3302-3311
2009
Sus scrofa (P09955)
Lepus, C.; Song, J.; Wang, Q.; Wagner, C.; Lindstrom, T.; Chu, C.; Sokolove, J.; Leung, L.; Robinson, W.
Carboxypeptidase B serves as a protective mediator in osteoarthritis
Arthritis Rheum.
66
101-106
2014
Homo sapiens, Mus musculus
Raz, A.; Dinparast Djadid, N.; Zakeri, S.
Molecular characterization of the carboxypeptidase B1 of Anopheles stephensi and its evaluation as a target for transmission-blocking vaccines
Infect. Immun.
81
2206-2216
2013
Anopheles stephensi (F1ALX3), Anopheles stephensi
Ktari, N.; Ben Khaled, H.; Lassoued, I.; Ghorbel, S.; Nasri, M.
Isolation and characteristics of carboxypeptidase B from zebra blenny (Salaria basilisca) viscera
J. Aquatic Food Product Technol.
23
208-220
2014
Salaria basilisca
-
Yoshimoto, N.; Itoh, T.; Inaba, Y.; Ishii, H.; Yamamoto, K.
Structural basis for inhibition of carboxypeptidase B by selenium-containing inhibitor: selenium coordinates to zinc in enzyme
J. Med. Chem.
56
7527-7535
2013
Sus scrofa (P09955), Sus scrofa
Kovacs, A.; Szabo, L.; Longstaff, C.; Tenekedjiev, K.; Machovich, R.; Kolev, K.
Ambivalent roles of carboxypeptidase B in the lytic susceptibility of fibrin
Thromb. Res.
133
80-87
2014
Sus scrofa
Akparov, V.; Sokolenko, N.; Timofeev, V.; Kuranova, I.
Structure of the complex of carboxypeptidase B and N-sulfamoyl-L-arginine
Acta Crystallogr. Sect. F
71
1335-1340
2015
Sus scrofa (P09955), Sus scrofa
Kim, D.G.; Kim, H.J.; Kim, H.J.
Effects of carboxypeptidase B treatment and elevated temperature on recombinant monoclonal antibody charge variants in cation-exchange chromatography analysis
Arch. Pharm. Res.
39
1472-1481
2016
Rattus norvegicus
Akparov, V.; Timofeev, V.; Maghsoudi, N.; Kuranova, I.
Three-dimensional structure of porcine pancreatic carboxypeptidase B with an acetate ion and two zinc atoms in the active site
Crystallogr. Rep.
62
249-253
2017
Sus scrofa (P09955)
-
Akparov, V.; Timofeev, V.; Khaliullin, I.; Svedas, V.; Kuranova, I.
Structure of the carboxypeptidase B complex with N-sulfamoyl-L-phenylalanine - a transition state analog of non-specific substrate
J. Biomol. Struct. Dyn.
36
956-965
2018
Sus scrofa (P09955)
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