Reference on EC 3.4.16.4 - serine-type D-Ala-D-Ala carboxypeptidase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Frere, J.M.; Moreno, R.; Ghuysen, J.M.; Perkins, H.R.; Dierickx, L.; Delcambe, L.
Molecular weight, amino acid composition and physicochemical properties of the exocellular DD-carboxypeptidase-transpeptidase of Streptomyces R39
Biochem. J.
143
233-240
1974
Streptomyces sp., Streptomyces sp. R39
Duez, C.; Piron-Fraipont, C.; Joris, B.; Dusart, J.; Urdea, M.S; Martial, J.A.; Frere, J.M.; Ghuysen, J.M.
Primary structure of the Streptomyces R61 extracellular DD-peptidase. 1. Cloning into Streptomyces lividans and nucleotide sequence of the gene [published erratum appears in Eur J Biochem 1994 Sep 15;224(3):1079
Eur. J. Biochem.
162
509-518
1987
Streptomyces sp.
Kelly, J.A.; Knox, J.R.; Zhao, H.; Frere, J.M.; Ghuysen, J.M.
Crystallographic mapping of beta-lactams bound to a D-alanyl-D-alanine peptidase target enzyme
J. Mol. Biol.
209
281-295
1989
Streptomyces sp.
Leyh-Bouille, M.; Nguyen-Disteche, M.; Pirlot, S.; Veithen, A.; Bourguignon, C.; Ghuysen, J.M.
Streptomyces K15 DD-peptidase-catalysed reactions with suicide beta-lactam carbonyl donors [published erratum appears in Biochem J 1986 Jun 15;236(3):following 933
Biochem. J.
235
177-182
1986
Streptomyces sp.
Laurent, G.; Durant, F.; Frere, J.M.; Klein, D.; Ghuysen, J.M.
Des-, syn- and anti-oxyimino-delta 3-cephalosporins. Intrinsic reactivity and reaction with RTEM-2 serine beta-lactamase and D-alanyl-D-alanine-cleaving serine and Zn2+-containing peptidases
Biochem. J.
218
933-937
1984
Actinomadura sp., Streptomyces sp.
Georgopapadakou, N.H.; Liu, F.Y.; Ryono, D.E.; Neubeck, R.; Gordon, E.M.; Pluscec, J.
Streptomyces R61 DD-carboxypeptidase: hydrolysis of X-D-alanyl-D-alanine peptides measured by a fluorometric assay
Anal. Biochem.
137
125-128
1984
Streptomyces sp.
Frere, J.M.; Joris, B.
Penicillin-sensitive enzymes in peptidoglycan biosynthesis
CRC Crit. Rev. Microbiol.
11
299-396
1985
Actinomadura sp., Streptomyces sp.
Ghuysen, J.M.; Frere, J.M.; Leyh-Bouille, M.; Nguyen-Disteche, M.; Coyette, J.; Dusart, J.; Charlier, P.; Dive, G.; Lamotte-Brasseur, J.
Bacterial wall peptidoglycan, DD-peptidases and beta-lactam antibiotics
Scand. J. Infect. Dis.
42
17-37
1984
Actinomadura sp., Streptomyces sp.
Frere, J.M.; Klein, D.; Kelly, J.A.; Ghuysen, J.M.
Interaction between monobactams and model D-alanyl-D-alanine-cleaving peptidases
FEMS Microbiol. Lett.
21
213-217
1984
Actinomadura sp., Streptomyces sp.
-
Joris, B.; Jacques, P.; Frere, J.M.; Ghuysen, J.M.; VanBeeumen, J.
Primary structure of the Streptomyces R61 extracellular DD-peptidase. 2. Amino acid sequence data
Eur. J. Biochem.
162
519-524
1987
Streptomyces sp.
Frere, J.M.; Kelly, J.A.; Klein, D.; Ghuysen, J.M.
delta 2- and delta 3-Cephalosporins, penicillinate and 6-unsubstituted penems. Intrinsic reactivity and interaction with beta-lactamases and D-alanyl-D-alanine-cleaving serine peptidases
Biochem. J.
203
223-234
1982
Streptomyces sp., Streptomyces sp. R39
DeCoen, J.L.; Lamotte-Brasseur, J.; Ghuysen, J.M.; Frere, J.M.; Perkins, H.R.
Conformational analysis of peptide substrates and inhibitors of the Zn2+ G and serine R61 D-alanyl-D-alanine peptidases
Eur. J. Biochem.
121
221-232
1981
Streptomyces sp.
Leyh-Bouille, M.; Nguyen-Disteche, M.; Ghuysen, J.M.
On the DD-carboxypeptidase enzyme system of Streptomyces strain K15
Eur. J. Biochem.
115
579-584
1981
Streptomyces sp.
Yocum, R.R.; Rasmussen, J.R.; Strominger, J.L.
The mechanism of action of penicillin. Penicillin acylates the active site of Bacillus stearothermophilus D-alanine carboxypeptidase
J. Biol. Chem.
255
3977-3986
1980
Geobacillus stearothermophilus
Varetto, L.; Frere, J.M.; Nguyen-Disteche, M.; Ghuysen, J.M.; Houssier, C.
The pH dependence of the active-site serine DD-peptidase of Streptomyces R61
Eur. J. Biochem.
162
525-531
1987
Streptomyces sp.
Murphy, B.P.; Pratt, R.F.
Evidence for an oxyanion hole in serine beta-lactamases and DD-peptidases
Biochem. J.
256
669-672
1988
Streptomyces sp.
Kelly, J.A.; Knox, J.R.; Moews, P.C.; Hite, G.J.; Bartolone, J.B.; Zhao, H.; Joris, B.; Frere, J.M.; Ghuysen, J.M.
2.8-A Structure of penicillin-sensitive D-alanyl carboxypeptidase-transpeptidase from Streptomyces R61 and complexes with beta-lactams
J. Biol. Chem.
260
6449-6458
1985
Streptomyces sp.
Yocum, R.R.; Waxman, D.J.; Rasmussen, J.R.; Strominger, J.L.
Mechanism of penicillin action: penicillin and substrate bind covalently to the same active site serine in two bacterial D-alanine carboxypeptidases
Proc. Natl. Acad. Sci. USA
76
2730-2734
1979
Geobacillus stearothermophilus, Bacillus subtilis
Coyette, J.; Ghuysen, J.M.; Fontana, R.
Solubilization and isolation of the membrane-bound DD-carboxypeptidase of Streptococcus faecalis ATCC9790. Properties of the purified enzyme
Eur. J. Biochem.
88
297-305
1978
Enterococcus faecalis
Waxman, D.J.; Strominger, J.L.
Cleavage of a COOH-terminal hydrophobic region from D-alanine carboxypeptidase, a penicillin-sensitive bacterial membrane enzyme. Characterization of active, water-soluble fragments
J. Biol. Chem.
254
4863-4875
1979
Geobacillus stearothermophilus
Marquet, A.; Nieto, M.; Diaz-Maurino, T.
Membrane-bound DD-carboxypeptidase and transpeptidase activities from Bacillus megaterium KM at pH 7. General properties, substrate specificity and inhibition by beta-lactam antibiotics
Eur. J. Biochem.
68
581-589
1976
Priestia megaterium, Priestia megaterium KM / ATCC 13632
Frere, J.M.; Duez, C.; Ghuysen, J.M.
Occurrence of a serine residue in the penicillin-binding site of the exocellular DD-carboxy-peptidase-transpeptidase from Streptomyces R61
FEBS Lett.
70
257-260
1976
Streptomyces sp.
Coyette, J.; Perkins, H.R.; Polacheck, I.; Shockman, G.D; Ghuysen, J.M.
Membrane-bound DD-carboxypeptidase and LD-transpeptidase of Streptococcus faecalis ATCC 9790
Eur. J. Biochem.
44
459-468
1974
Enterococcus faecalis
Yocum, R.R.; Blumberg, P.M.; Strominger, J.I.
Purification and characterization of the thermophilic D-alanine carboxypeptidase from membranes of Bacillus stearothermophilus
J. Biol. Chem.
249
4863-4871
1974
Geobacillus stearothermophilus
Van der Linden, M.P.G.; Mottl, H.; Keck, W.
Cytoplasmic high-level expression of a soluble, enzymatically active form of the Escherichia coli penicillin-binding protein 5 and purification by dye chromatography
Eur. J. Biochem.
204
197-202
1992
Streptomyces sp., Escherichia coli, Streptomyces sp. R39
Perkins, H.R.; Nieto, M.; Frere, J.M.; Leyh-Bouille, M.; Ghuysen, J.M.
Streptomyces DD-carboxypeptidases as transpeptidases. The specificity for amino compounds acting as carboxyl acceptors
Biochem. J.
131
707-718
1973
Streptomyces sp., Streptomyces sp. R39, Streptomyces sp. K11
Leyh-Bouille, M.; Coyette, J.; Ghuysen, J.M.; Idczak, J.; Perkins, H.R.; Nieto, M.
Penicillin-sensitive DD-carboxypeptidase from Streptomyces strain R 61
Biochemistry
10
2163-2170
1971
Streptomyces sp.
Kimura, Y.; Takashima, Y.; Tokumasu, Y.; Sato, M.
Molecular cloning, sequence analysis, and characterization of a penicillin-resistant DD-carboxypeptidase of Myxococcus xanthus
J. Bacteriol.
181
4696-4699
1999
Streptomyces sp., Myxococcus xanthus
Fonze, E.; Vermeire, M.; Nguyen-Disteche, M.; Brasseur, R.; Charlier, P.
The crystal structure of a penicilloyl-serine transferase of intermediate penicillin sensitivity. The DD-transpeptidase of streptomyces K15
J. Biol. Chem.
274
21853-21860
1999
Streptomyces sp. (P39042)
Duez, C.; Joris, B.; Frere, J.M.; Ghuysen, J.M.
The penicillin-binding site in the exocellular DD-carboxypeptidase-transpeptidase of Actinomadura R39
Biochem. J.
193
83-86
1981
Actinomadura sp.
Palomeque-Messia, P.; Quittre, V.; Leyh-Bouille, M.; Nguyen-Disteche, M.; Gershater, C.J.L.; Dacey, I.K.; Dusart, J.; van Beeumen, J.; Ghuysen, J.M.
Secretion by overexpression and purification of the water-soluble Streptomyces K15 DD-transpeptidase/penicillin-binding protein
Biochem. J.
288
87-91
1992
Streptomyces sp.
Wright, G.D.; Molinas, C.; Arthur, M.; Courvalin, P.; Walsh, C.T.
Characterization of vanY, a DD-carboxypeptidase from vancomycin-resistant Enterococcus faecium BM4147
Antimicrob. Agents Chemother.
36
1514-1518
1992
Enterococcus faecium, Enterococcus faecium BM4147
Eng, G.Y.; Maxwell, R.J.
Effect of immobilization on the penicillin binding and reactivity properties of DD-peptidase from Streptomyces R61
J. Mol. Recognit.
9
706-714
1996
Streptomyces sp.
Cabaret, D.; Liu, J.; Wakselman, M.; Pratt, R.F.; Xu, Y.
Functionalized depsipeptides, substrates and inhibitors of beta-lactamases and DD-peptidases
Bioorg. Med. Chem. Lett.
2
757-771
1994
Streptomyces sp.
Kelly, J.A.; Kuzin, A.P.
The refined crystallographic structure of a DD-peptidase penicillin-target enzyme at 1.6 A resolution
J. Mol. Biol.
254
223-236
1995
Streptomyces sp. (P15555)
Kelly, J.A.; Waley, S.G.; Adam, M.; Frere, J.M.
Crystalline enzyme kinetics: activity of the Streptomyces R61 D-alanyl-D-alanine peptidase
Biochim. Biophys. Acta
1119
256-260
1992
Streptomyces sp.
Wu, Z.; Walsh, C.
Dithiol compounds: Potent, time-dependent inhibitors of VanX, a zinc-dependent D,D-dipeptidase required for vancomycin resistance in Enterococcus faecium
J. Am. Chem. Soc.
118
1785-1786
1996
Enterococcus faecium
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Kariyama, R.; Massidda, O.; Daneo-Moore, L.; Shockman, G.D.
Properties of cell wall-associated DD-carboxypeptidase of Enterococcus hirae (Streptococcus faecium) ATCC 9790 extracted with alkali
J. Bacteriol.
172
3718-3724
1990
Enterococcus hirae
Erpicum, T.; Granier, B.; Delcour, M.; Lenzini, V.M.; Nguyen-Disteche, M.; Dusart, J.; Frere, J.M.
Enzyme production by genetically engineered Streptomyces strains: Influence of culture conditions
Biotechnol. Bioeng.
35
719-726
1990
Streptomyces sp.
Anderson, J.W.; Pratt, R.F.
Dipeptide binding to the extended active site of the Streptomyces R61 D-alanyl-D-alanine-peptidase: the path to a specific substrate
Biochemistry
39
12200-12209
2000
Streptomyces sp. R61
Silvaggi, N.R.; Anderson, J.W.; Brinsmade, S.R.; Pratt, R.F.; Kelly, J.A.
The crystal structure of phosphonate-inhibited D-Ala-D-Ala peptidase reveals an analogue of a tetrahedral transition state
Biochemistry
42
1199-1208
2003
Streptomyces sp. (P15555)
Rhazi, N.; Charlier, P.; Dehareng, D.; Engher, D.; Vermeire, M.; Frere, J.M.; Nguyen-Disteche, M.; Fonze, E.
Catalytic mechanism of the Streptomyces K15 DD-transpeptidase/penicillin-binding protein probed by site-directed mutagenesis and structural analysis
Biochemistry
42
2895-2906
2003
Streptomyces sp. (P39042)
Stefanova, M.E.; Davies, C.; Nicholas, R.A.; Gutheil, W.G.
pH, inhibitor, and substrate specificity studies on Escherichia coli penicillin-binding protein 5
Biochim. Biophys. Acta
1597
292-300
2002
Escherichia coli
Davies, C.; White, S.W.; Nicholas, R.A.
Crystal structure of a deacylation-defective mutant of penicillin-binding protein 5 at 2.3-A resolution
J. Biol. Chem.
276
616-623
2001
Escherichia coli
Nicholas, R.A.; Krings, S.; Tomberg, J.; Nicola, G.; Davies, C.
Crystal structure of wild-type penicillin-binding protein 5 from Escherichia coli: implications for deacylation of the acyl-enzyme complex
J. Biol. Chem.
278
52826-52833
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Escherichia coli
Hesek, D.; Suvorov, M.; Morio, K.; Lee, M.; Brown, S.; Vakulenko, S.B.; Mobashery, S.
Synthetic peptidoglycan substrates for penicillin-binding protein 5 of Gram-negative bacteria
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Escherichia coli
Reynolds, P.E.; Ambur, O.H.; Casadewall, B.; Courvalin, P.
The VanY(D) DD-carboxypeptidase of Enterococcus faecium BM4339 is a penicillin-binding protein
Microbiology
147
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2001
Enterococcus faecium, Enterococcus faecium BM4339
Lee, W.; McDonough, M.A.; Kotra, L.P.; Li, Z.H.; Silvaggi, N.R.; Takeda, Y.; Kelly, J.A.; Mobashery, S.
A 1.2-.ANG. snapshot of the final step of bacterial cell wall biosynthesis
Proc. Natl. Acad. Sci. USA
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2001
Streptomyces sp. (P15555), Streptomyces sp.
Beadle, B.M.; Nicholas, R.A.; Shoichet, B.K.
Interaction energies between beta-lactam antibiotics and E. coli penicillin-binding protein 5 by reversible thermal denaturation
Protein Sci.
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2001
Escherichia coli
Bochtler, M.; Odintsov, S.G.; Marcyjaniak, M.; Sabala, I.
Similar active sites in lysostaphins and D-Ala-D-Ala metallopeptidases
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Streptomyces albus
Suginaka, H.; Shimatani, M.; Ogawa, M.; Kotani, S.
Effect of piperacillin on D-alanine carboxypeptidase activities from Pseudomonas aeruginosa
J. Gen. Microbiol.
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Pseudomonas aeruginosa
Zervosen, A.; Lu, W.P.; Chen, Z.; White, R.E.; Demuth Jr., T.P.; Frre, J.M.
Interactions between penicillin-binding proteins (PBPs) and two novel classes of PBP inhibitors, arylalkylidene rhodanines and arylalkylidene iminothiazolidin-4-ones
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Actinomadura sp., Escherichia coli, Streptomyces sp. R61
Diaz, N.; Sordo, T.L.; Suarez, D.
Insights into the base catalysis exerted by the DD-transpeptidase from Streptomyces K15: A molecular dynamics study
Biochemistry
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Streptomyces sp.
Llinas, A.; Ahmed, N.; Cordaro, M.; Laws, A.P.; Frre, J.M.; Delmarcelle, M.; Silvaggi, N.R.; Kelly, J.A.; Page, M.I.
Inactivation of bacterial DD-peptidase by beta-sultams
Biochemistry
44
7738-7746
2005
Streptomyces sp. R61 (P15555), Streptomyces sp. R61
Nicola, G.; Peddi, S.; Stefanova, M.; Nicholas, R.A.; Gutheil, W.G.; Davies, C.
Crystal structure of Escherichia coli penicillin-binding protein 5 bound to a tripeptide boronic acid inhibitor: A role for Ser-110 in deacylation
Biochemistry
44
8207-8217
2005
Escherichia coli (P0AEB2), Escherichia coli
Kumar, I.; Pratt, R.F.
Transpeptidation reactions of a specific substrate catalyzed by the Streptomyces R61 DD-Peptidase: The structural basis of acyl acceptor specificity
Biochemistry
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9961 -9970
2005
Streptomyces sp. R61
Kumar, I.; Pratt, R.F.
Transpeptidation reactions of a specific substrate catalyzed by the Streptomyces R61 DD-peptidase: Characterization of a chromogenic substrate and acyl acceptor design
Biochemistry
44
9971 -9979
2005
Streptomyces sp. R61
Kikuchi, H.; Kim, S.; Watanabe, K.; Watarai, M.
Brucella abortus d-alanyl-d-alanine carboxypeptidase contributes to its intracellular replication and resistance against nitric oxide
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Brucella abortus
Priyadarshini, R.; Popham, D.L.; Young, K.D.
Daughter cell separation by penicillin-binding proteins and peptidoglycan amidases in Escherichia coli
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Escherichia coli
Morlot, C.; Pernot, L.; Le Gouellec, A.; Di Guilmi, A.M.; Vernet, T.; Dideberg, O.; Dessen, A.
Crystal structure of a peptidoglycan synthesis regulatory factor (PBP3) from Streptococcus pneumoniae
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Streptomyces pneumoniae
Sauvage, E.; Herman, R.; Petrella, S.; Duez, C.; Bouillenne, F.; Frre, J.M.; Charlier, P.
Crystal structure of the Actinomadura R39 DD-peptidase reveals new domains in penicillin-binding proteins
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Actinomadura sp., Escherichia coli
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Crystal structures of complexes between the R61 DD-peptidase and peptidoglycan-mimetic beta-lactams: a non-covalent complex with a "perfect penicillin"
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Streptomyces sp. R61 (P15555), Streptomyces sp. R61
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Streptomyces sp. R61
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The D,D-carboxypeptidase PBP3 organizes the division process of Streptococcus pneumoniae
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Streptococcus pneumoniae
Scheffers, D.J.; Jones, L.J.F.; Errington, J.
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Streptomyces sp. R61
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Escherichia coli
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Priestia megaterium, Priestia megaterium KM / ATCC 13632
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Escherichia coli
Adediran, S.A.; Kumar, I.; Pratt, R.F.
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Biochemistry
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Streptomyces sp. R61
Josephine, H.R.; Charlier, P.; Davies, C.; Nicholas, R.A.; Pratt, R.F.
Reactivity of penicillin-binding proteins with peptidoglycan-mimetic beta-lactams: whats wrong with these enzymes?
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Streptococcus pneumoniae, Escherichia coli, Streptomyces sp. R61, Actinomadura sp. R39
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Synthesis and beta-lactamase reactivity of alpha -substituted phenaceturates
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Neisseria gonorrhoeae, Streptomyces sp. R61, Actinomadura sp. R39
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Bacillus subtilis, Caulobacter vibrioides, Streptomyces sp., Streptococcus pneumoniae, Escherichia coli, Haemophilus influenzae, Staphylococcus aureus, Neisseria gonorrhoeae, Streptomyces sp. R61, Streptomyces sp. K15
Cierpucha, M.; Panfil, I.; Danh, T.T.; Chmielewski, M.; Kurzatkowski, W.; Rajnisz, A.; Solecka, J.
Synthesis of 3-Substituted-clavams: Antifungal Properties, DD-Peptidase and beta-Lactamase Inhibition
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Saccharopolyspora erythraea
Okazaki, S.; Suzuki, A.; Komeda, H.; Yamaguchi, S.; Asano, Y.; Yamane, T.
Crystal structure and functional characterization of a D-stereospecific amino acid amidase from Ochrobactrum anthropi SV3, a new member of the penicillin-recognizing proteins
J. Mol. Biol.
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2007
Brucella anthropi (Q9LCC8), Brucella anthropi
Sauvage, E.; Duez, C.; Herman, R.; Kerff, F.; Petrella, S.; Anderson, J.W.; Adediran, S.A.; Pratt, R.F.; Frere, J.M.; Charlier, P.
Crystal structure of the Bacillus subtilis penicillin-binding protein 4a, and its complex with a peptidoglycan mimetic peptide
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Bacillus subtilis (P39844)
Macheboeuf, P.; Lemaire, D.; Martins, A.D.; Dideberg, O.; Jamin, M.; Dessen, A.
Trapping of an acyl-enzyme intermediate in a penicillin-binding protein (PBP)-catalyzed reaction
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Streptococcus pneumoniae
Maglia, G.; Jonckheer, A.; De Maeyer, M.; Frere, J.M.; Engelborghs, Y.
An unusual red-edge excitation and time-dependent Stokes shift in the single tryptophan mutant protein DD-carboxypeptidase from Streptomyces: the role of dynamics and tryptophan rotamers
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Streptomyces sp. R61
Danh, T.T.; Borsuk, K.; Solecka, J.; Chmielewski, M.
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Saccharopolyspora erythraea
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Clarke, T.; Kawai, F.; Park, S.Y.; Tame, J.; Dowson, C.; Roper, D.
Mutational analysis of the substrate specificity of Escherichia coli penicillin binding protein 4 (PBP4)
Biochemistry
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Escherichia coli K-12 (P24228)
Shi, Q.; Meroueh, S.O.; Fisher, J.F.; Mobashery, S.
Investigation of the mechanism of the cell wall DD-carboxypeptidase reaction of penicillin-binding protein 5 of Escherichia coli by quantum mechanics/molecular mechanics calculations
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Escherichia coli (P0AEB2), Escherichia coli
Sauvage, E.; Powell, A.J.; Heilemann, J.; Josephine, H.R.; Charlier, P.; Davies, C.; Pratt, R.F.
Crystal structures of complexes of bacterial DD-peptidases with peptidoglycan-mimetic ligands: the substrate specificity puzzle
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Escherichia coli K-12 (P0AEB2), Actinomadura sp. R39 (P39045)
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Physiological functions of D-alanine carboxypeptidases in Escherichia coli
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Escherichia coli (P0AEB2)
Chowdhury, C.; Nayak, T.R.; Young, K.D.; Ghosh, A.S.
A weak DD-carboxypeptidase activity explains the inability of PBP 6 to substitute for PBP 5 in maintaining normal cell shape in Escherichia coli
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Escherichia coli
Sarkar, S.K.; Chowdhury, C.; Ghosh, A.S.
Deletion of penicillin-binding protein 5 (PBP5) sensitises Escherichia coli cells to beta-lactam agents
Int. J. Antimicrob. Agents
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2010
Escherichia coli
Daniel, P.I.; Zajicek, J.; Zhang, W.; Shi, Q.; Fisher, J.F.; Mobashery, S.
Elucidation of the structure of the membrane anchor of penicillin-binding protein 5 of Escherichia coli
J. Am. Chem. Soc.
132
4110-4118
2010
Escherichia coli
Inglis, S.R.; Zervosen, A.; Woon, E.C.; Gerards, T.; Teller, N.; Fischer, D.S.; Luxen, A.; Schofield, C.J.
Synthesis and evaluation of 3-(dihydroxyboryl)benzoic acids as D,D-carboxypeptidase R39 inhibitors
J. Med. Chem.
52
6097-6106
2009
Actinomadura sp. R39 (P39045)
Lavollay, M.; Arthur, M.; Fourgeaud, M.; Dubost, L.; Marie, A.; Riegel, P.; Gutmann, L.; Mainardi, J.L.
The beta-lactam-sensitive D,D-carboxypeptidase activity of Pbp4 controls the L,D and D,D transpeptidation pathways in Corynebacterium jeikeium
Mol. Microbiol.
74
650-661
2009
Corynebacterium jeikeium
Hung, W.C.; Jane, W.N.; Wong, H.C.
Association of a D-alanyl-D-alanine carboxypeptidase gene with the formation of aberrantly shaped cells during the induction of viable but nonculturable Vibrio parahaemolyticus
Appl. Environ. Microbiol.
79
7305-7312
2013
Vibrio parahaemolyticus (Q87LZ0), Vibrio parahaemolyticus
Dzhekieva, L.; Adediran, S.A.; Herman, R.; Kerff, F.; Duez, C.; Charlier, P.; Sauvage, E.; Pratt, R.F.
Inhibition of DD-peptidases by a specific trifluoroketone: crystal structure of a complex with the Actinomadura R39 DD-peptidase
Biochemistry
52
2128-2138
2013
Actinomadura sp. (P39045)
Binda, E.; Marcone, G.; Berini, F.; Pollegioni, L.; Marinelli, F.
Streptomyces spp. as efficient expression system for a D,D-peptidase/D,D-carboxypeptidase involved in glycopeptide antibiotic resistance
BMC Biotechnol.
13
24
2013
Nonomuraea sp. (Q7WZ84), Nonomuraea sp., Nonomuraea sp. ATCC 39727 (Q7WZ84)
Moell, A.; Doerr, T.; Alvarez, L.; Davis, B.M.; Cava, F.; Waldor, M.K.
A D, D-carboxypeptidase is required for Vibrio cholerae halotolerance
Environ. Microbiol.
17
527-540
2015
Vibrio cholerae (Q9KTF5), Vibrio cholerae, Vibrio cholerae ATCC 39315 (Q9KTF5)
Binda, E.; Marcone, G.L.; Pollegioni, L.; Marinelli, F.
Characterization of VanYn, a novel D,D-peptidase/D,D-carboxypeptidase involved in glycopeptide antibiotic resistance in Nonomuraea sp. ATCC 39727
FEBS J.
279
3203-3213
2012
Nonomuraea sp. (Q7WZ84), Nonomuraea sp. ATCC 39727 (Q7WZ84)
Hargis, J.; Vankayala, S.; White, J.; Woodcock, H.
Identification and characterization of noncovalent interactions that drive binding and specificity in DD-peptidases and beta-lactamases
J. Chem. Theory Comput.
10
855-864
2014
Streptomyces sp. (P15555)
Pelto, R.B.; Pratt, R.F.
Kinetics and stereochemistry of hydrolysis of an N-(phenylacetyl)-alpha-hydroxyglycine ester catalyzed by serine beta-lactamases and DD-peptidases
Org. Biomol. Chem.
10
7356-7362
2012
Actinomadura sp. (P39045), Streptomyces sp. (P15555)
Meziane-Cherif, D.; Stogios, P.J.; Evdokimova, E.; Savchenko, A.; Courvalin, P.
Structural basis for the evolution of vancomycin resistance D,D-peptidases
Proc. Natl. Acad. Sci. USA
111
5872-5877
2014
Enterococcus faecalis
Yang, H.; Hu, J.; Lu, X.; Wang, F.; Shen, W.; Hu, W.; Wang, L.; Chen, X.; Liu, L.
Improving extracellular protein production in Escherichia coli by overexpressing D,D-carboxypeptidase to perturb peptidoglycan network synthesis and structure
Appl. Microbiol. Biotechnol.
103
793-806
2019
Escherichia coli
Hu, J.; Lu, X.; Wang, H.; Wang, F.; Zhao, Y.; Shen, W.; Yang, H.; Chen, X.
Enhancing extracellular protein production in Escherichia coli by deleting the D-alanyl-D-alanine carboxypeptidase gene dacC
Eng. Life Sci.
19
270-278
2019
Escherichia coli
-
Hargis, J.C.; Vankayala, S.L.; White, J.K.; Woodcock, H.L.
Identification and characterization of noncovalent interactions that drive binding and specificity in DD-peptidases and beta-lactamases
J. Chem. Theory Comput.
10
855-864
2014
Streptomyces sp. R61 (P15555)
Meiresonne, N.; van der Ploeg, R.; Hink, M.; den Blaauwen, T.
Activity-related conformational changes in D,D-carboxypeptidases revealed by in vivo periplasmic Foerster resonance energy transfer assay in Escherichia coli
mBio
8
e01089
2017
Escherichia coli
Rioseras, B.; Yaguee, P.; Lopez-Garcia, M.T.; Gonzalez-Quinonez, N.; Binda, E.; Marinelli, F.; Manteca, A.
Characterization of SCO4439, a D-alanyl-D-alanine carboxypeptidase involved in spore cell wall maturation, resistance, and germination in Streptomyces coelicolor
Sci. Rep.
6
21659
2016
Streptomyces coelicolor (Q9KZY7), Streptomyces coelicolor, Streptomyces coelicolor ATCC BAA-471 (Q9KZY7)
Barriere, Q.; Guefrachi, I.; Gully, D.; Lamouche, F.; Pierre, O.; Fardoux, J.; Chaintreuil, C.; Alunni, B.; Timchenko, T.; Giraud, E.; Mergaert, P.
Integrated roles of BclA and DD-carboxypeptidase 1 in Bradyrhizobium differentiation within NCR-producing and NCR-lacking root nodules
Sci. Rep.
7
9063
2017
Bradyrhizobium diazoefficiens, Bradyrhizobium diazoefficiens USDA 110
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