Information on EC 3.4.14.14 - [mycofactocin precursor peptide] peptidase

for references in articles please use BRENDA:EC3.4.14.14
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EC Tree
IUBMB Comments
Requires Fe2+ ad Zn2+. The enzyme participates in the biosynthesis of the enzyme cofactor mycofactocin. It catalyses cleavage of the mycofactocin precursor peptide following its modification by MftC to liberate its final two residues, which consist of a cross-linked valine-tyramine dipeptide.
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The expected taxonomic range for this enzyme is: Mycobacteriaceae
Reaction Schemes
C-terminal [mycofactocin precursor peptide]-glycyl-3-amino-5-[(4-hydroxyphenyl)methyl]-4,4-dimethylpyrrolidin-2-one
+
=
C-terminal [mycofactocin precursor peptide]-glycine
+
Synonyms
LI98_07105, mftE, Rv0695, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
C-terminal [mycofactocin precursor peptide]-glycyl-3-amino-5-[(4-hydroxyphenyl)methyl]-4,4-dimethylpyrrolidin-2-one + H2O = C-terminal [mycofactocin precursor peptide]-glycine + 3-amino-5-[(4-hydroxyphenyl)methyl]-4,4-dimethylpyrrolidin-2-one
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PATHWAY SOURCE
PATHWAYS
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