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Disease on EC 3.4.13.9 - Xaa-Pro dipeptidase

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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Abortion, Spontaneous
Comparison of prolidase enzyme activities of maternal serum and placental tissue in patients with early pregnancy failure.
Decreased serum prolidase activity and increased oxidative stress in early pregnancy loss.
Abruptio Placentae
Comparison of tissue prolidase enzyme activity and serum oxidative stress level between pregnant women with placental abruption and those with a healthy pregnancy.
Abscess
Plasma prolidase activity as a possible diagnostic index of chronic hepatic abscess in cattle.
Acromegaly
High Prolidase Levels may be a Marker of Irreversible Extracellular Matrix Changes in Controlled Acromegaly Patients?
Adenocarcinoma
Betulinic acid inhibits the expression of hypoxia-inducible factor 1alpha and vascular endothelial growth factor in human endometrial adenocarcinoma cells.
Prolidase activity and beta 1 integrin expression in moderately and poorly differentiated lung adenocarcinomas.
Adenocarcinoma of Lung
Prolidase activity and beta 1 integrin expression in moderately and poorly differentiated lung adenocarcinomas.
Prolidase and prolinase activities in moderately and poorly differentiated lung adenocarcinoma.
Alopecia Areata
Evaluation of Serum Paraoxonase, Arylesterase, Prolidase Activities and Oxidative Stress in Patients with Alopecia Areata.
Alzheimer Disease
A plasma proteolysis pathway comprising blood coagulation proteases.
Increased prolidase activity in Alzheimer's dementia: A case-control study.
Relationship of cognitive performance with prolidase and oxidative stress in Alzheimer disease.
Anemia
Prolidase deficiency associated with hemoglobin O trait and microcytic anemia.
Anemia, Sickle Cell
Leg ulcers in childhood: A multicenter study in France.
Aneurysm
Prolidase Activity in Patients With Coronary Artery Aneurysm.
argininosuccinate lyase deficiency
Population screening in a Druze community: the challenge and the reward.
Argininosuccinic Aciduria
Population screening in a Druze community: the challenge and the reward.
Arthritis
Prolidase deficiency: a rare aetiology of arthritis.
Arthritis, Rheumatoid
Serum prolidase activity in ankylosing spondylitis and rheumatoid arthritis.
Asthma
Serum prolidase activity and oxidative status in patients with bronchial asthma.
The effects of different treatments on prolidase and antioxidant enzyme activities in patients with bronchial asthma.
Atrial Fibrillation
Association of prolidase activity, oxidative parameters, and presence of atrial fibrillation in patients with mitral stenosis.
The Relationship Between Prolidase Activity and Atrial Electromechanical Changes in Patients with Paroxysmal Atrial Fibrillation.
Autoimmune Lymphoproliferative Syndrome
Rare diseases that mimic Systemic Lupus Erythematosus (Lupus mimickers).
Azoospermia
Prolidase enzyme activity in varicose venous walls related to sperm count in patients with varicocele.
beta-Thalassemia
Prolidase activity and oxidative status in patients with thalassemia major.
Blister
Prolidase activity in chronic wound and blister fluids.
[Prolidase deficiency with various clinical conditions including hyper-IgE and multiple lung bulla formation]
Bone Diseases
The role of prolidase activity in the diagnosis of uremic bone disease.
Bone Resorption
Correlations of serum prolidase activity between bone turnover markers and mineral density in postmenopausal osteoporosis.
Evaluation of the effect of low-dose oral theophylline therapy on some bone turnover markers and serum prolidase I activity in mild asthmatics.
Serum prolidase activity as a marker of osteoporosis in type 2 diabetes mellitus.
Breast Neoplasms
?IIb?3-integrin Ligands: Abciximab and Eptifibatide as Proapoptotic Factors in MCF-7 Human Breast Cancer Cells.
Acetylsalicylic acid as a potential regulator of prolidase-convertible pro-drugs in control and neoplastic cells.
Enhanced prolidase activity and decreased collagen content in breast cancer tissue.
Estrogen-dependent regulation of prolidase activity in breast cancer MCF-7 cells.
Estrogenic and antiestrogenic effects of raloxifene on collagen metabolism in breast cancer MCF-7 cells.
Extracellular matrix and HIF-1 signaling: the role of prolidase.
Overexpression of Prolidase Induces Autophagic Death in MCF-7 Breast Cancer Cells.
Prolidase activity and oxidative stress in patients with breast carcinoma A prospective randomized case-controlled study.
Prolidase in human breast cancer MCF-7 cells.
Proline analogue of melphalan as a prodrug susceptible to the action of prolidase in breast cancer MDA-MB 231 cells.
Proline analogue of melphalan as a prolidase-convertible pro-drug in breast cancer MCF-7 cells.
Serum prolidase I activity and some bone metabolic markers in patients with breast cancer: in relation to menopausal status.
The effect of estrogen on prolidase-dependent regulation of HIF-1? expression in breast cancer cells.
Brucellosis
Serum prolidase level in patients with brucellosis and its possible relationship with pathogenesis of the disease: a prospective observational study
Bruxism
Evaluation of the oxidative stress level and serum prolidase activity in patients with sleep bruxism.
carbamoyl-phosphate synthase (ammonia) deficiency
Population screening in a Druze community: the challenge and the reward.
Carcinogenesis
A Mn(II)-Mn(II) center in human prolidase.
Deregulation of collagen metabolism in human stomach cancer.
PROLIDASE: A Review from Discovery to its Role in Health and Disease.
Carcinoma
Collagen metabolism disturbances are accompanied by an increase in prolidase activity in lung carcinoma planoepitheliale.
Prolidase activity and oxidative stress in patients with breast carcinoma A prospective randomized case-controlled study.
Serum prolidase activity, oxidative stress, and antioxidant enzyme levels in patients with renal cell carcinoma.
Serum prolidase activity, total oxidant/antioxidant, and nitric oxide levels in patients with esophageal squamous cell carcinoma.
Squamous cell carcinoma of the leg in a patient with prolidase deficiency.
Carcinoma, Hepatocellular
Assessment of the correlation between serum prolidase and alpha-fetoprotein levels in patients with hepatocellular carcinoma.
Effect of ethanol on prolidase I and prolinase activity in the human hepatoma cell line Hep G2.
Carcinoma, Ovarian Epithelial
Assessment of preoperative serum prolidase activity in epithelial ovarian cancer.
Carcinoma, Renal Cell
Serum prolidase activity, oxidative stress, and antioxidant enzyme levels in patients with renal cell carcinoma.
Carcinoma, Squamous Cell
Squamous cell carcinoma of the leg in a patient with prolidase deficiency.
Cardiomegaly
Developmental cardiac hypertrophy in a mouse model of prolidase deficiency.
Cardiomyopathies
Serum prolidase activity in idiopathic and ischemic cardiomyopathy patients.
Cardiovascular Diseases
Serum prolidase enzyme activity in obese subjects and its relationship with oxidative stress markers.
Castleman Disease
Rare diseases that mimic Systemic Lupus Erythematosus (Lupus mimickers).
Cellulitis
Prolidase deficiency: the use of topical proline for treatment of leg ulcers.
Chorioamnionitis
Maternal plasma prolidase, matrix metalloproteinases 1 and 13, and oxidative stress levels in pregnancies complicated by preterm premature rupture of the membranes and chorioamnionitis.
Prolidase, matrix metalloproteinases 1 and 13 activity, oxidative-antioxidative status as a marker of preterm premature rupture of membranes and chorioamnionitis in maternal vaginal washing fluids.
Clubfoot
A preliminary study pointing out the role of serum prolidase activity and oxidative-antioxidative status parameters during the treatment process of patients with idiopathic clubfoot.
Coinfection
Modulation of vaginal immune response among pregnant women with bacterial vaginosis by Trichomonas vaginalis, Chlamydia trachomatis, Neisseria gonorrhoeae, and yeast.
Colitis
Elevated fecal peptidase D at onset of colitis in Galphai2-/- mice, a mouse model of IBD.
Colonic Neoplasms
Thrombin-dependent modulation of ?1-integrin-mediated signaling up-regulates prolidase and HIF-1? through p-FAK in colorectal cancer cells.
Colorectal Neoplasms
Extracellular matrix and HIF-1 signaling: the role of prolidase.
Thrombin-dependent modulation of ?1-integrin-mediated signaling up-regulates prolidase and HIF-1? through p-FAK in colorectal cancer cells.
Communicable Diseases
Leg ulcers in childhood: A multicenter study in France.
PROLIDASE: A Review from Discovery to its Role in Health and Disease.
Congenital Abnormalities
A Case of Prolidase Deficiency Accompanying Leg Ulcers.
INFLAMMATORY BOWEL DISEASE-LIKE PHENOTYPE IN A YOUNG GIRL WITH PROLIDASE DEFICIENCY: A NEW SPECTRUM OF CLINICAL MANIFESTATION.
Ulcus cruris associated with prolidase deficiency.
Coronary Aneurysm
Prolidase Activity in Patients With Coronary Artery Aneurysm.
Coronary Artery Disease
Circulating Prolidase Activity in Patients with Myocardial Infarction.
Relationship Between Echocardiographically Evaluated Aortic Stiffness and Prolidase Activity in Aortic Tissue of Patients with Critical Coronary Artery Disease.
The association of serum prolidase activity with the presence and severity of coronary artery disease.
Coronary Occlusion
Relationship Between Echocardiographically Evaluated Aortic Stiffness and Prolidase Activity in Aortic Tissue of Patients with Critical Coronary Artery Disease.
Crohn Disease
A Novel Manifestation of Prolidase Deficiency in a Toddler Diagnosed With Very-early-onset Crohn Disease.
Topical tacrolimus therapy in the management of lower extremity ulcers due to prolidase deficiency.
Cystic Fibrosis
Chronic lung disease and cystic fibrosis phenotype in prolidase deficiency: a newly recognized association.
Cystinuria
Quebec neonatal mass urinary screening programme: from micromolecules to macromolecules.
Cystitis
Prolidase deficiency: a case report and literature review.
Cysts
Plasma prolidase levels as a biomarker for polycystic ovary syndrome.
Deficiency Diseases
Structural basis for prolidase deficiency disease mechanisms.
Dementia
Increased prolidase activity in Alzheimer's dementia: A case-control study.
Dental Caries
[Hereditary prolidase deficiency. Contribution to differential therapy refractory leg ulcer diagnosis]
Dermatitis
Activity of prolidase isoenzymes in the rat brain: Subcellular and regional distribution during development.
Differential Diagnosis of Genetic Disorders Associated with Moderate to Severe Refractory Eczema and Elevated Immunoglobulin E.
Prolidase deficiency with hyperimmunoglobulin E: a case report.
Dermatitis, Atopic
Differential Diagnosis of Genetic Disorders Associated with Moderate to Severe Refractory Eczema and Elevated Immunoglobulin E.
Dermatomyositis
Leg ulcers in childhood: A multicenter study in France.
Developmental Dysplasia of the Hip
Serum prolidase activity and oxidative-antioxidative status in patients with developmental dysplasia of the hip and its relationship with radiographic severity.
The association of serum prolidase activity with developmental dysplasia of the hip.
Diabetes Mellitus
Characterization of prolidase activity using capillary electrophoresis with Tris(2,2'-bipyridyl)ruthenium(II) electrochemiluminescence detection and application to evaluate collagen degradation in diabetes mellitus.
Serum prolidase activity as a marker of osteoporosis in type 2 diabetes mellitus.
Serum prolidase enzyme activity and oxidative stress levels in patients with diabetic neuropathy.
The Value of Serum Prolidase Activity in Progression of Microalbuminuria in Patients With Type 2 Diabetes Mellitus.
Diabetes Mellitus, Type 2
Serum prolidase activity as a marker of osteoporosis in type 2 diabetes mellitus.
The Value of Serum Prolidase Activity in Progression of Microalbuminuria in Patients With Type 2 Diabetes Mellitus.
Diabetic Foot
Serum prolidase activity in diabetic foot ulcers.
Diabetic Nephropathies
Serum prolidase activity and oxidative stress in diabetic nephropathy and end stage renal disease: a correlative study with glucose and creatinine.
Serum prolidase activity as a marker of osteoporosis in type 2 diabetes mellitus.
Diabetic Neuropathies
Oxidative Stress And Prolidase Enzyme Activity In The Pathogenesis Of Primary Varicose Veins.
Serum prolidase activity and oxidative status in patients with diabetic neuropathy.
Serum prolidase enzyme activity and oxidative stress levels in patients with diabetic neuropathy.
Ecchymosis
[Prolidase and manganese deficiency. Apropos of a case: diagnosis and treatment]
Eczema
Differential Diagnosis of Genetic Disorders Associated with Moderate to Severe Refractory Eczema and Elevated Immunoglobulin E.
Encephalitis, Tick-Borne
A database of human genes and a gene network involved in response to tick-borne encephalitis virus infection.
Endometrial Neoplasms
Serum prolidase activity and oxidative status in patients with stage I endometrial cancer.
Epidermolysis Bullosa
Epidermolysis bullosa simplex: expression of gelatinase activity in cultured human skin fibroblasts.
Epidermolysis Bullosa Simplex
Epidermolysis bullosa simplex: expression of gelatinase activity in cultured human skin fibroblasts.
Epilepsy
Serum Prolidase Enzyme Activity Level: Not a Predictive Biomarker for Epilepsy.
The Serum Prolidase Enzyme Activity as a Biomarker for Evaluation of the Subclinical Vascular Damage in Children with Epilepsy.
Erectile Dysfunction
Acute effect of phosphodiesterase type 5 inhibitor on serum oxidative status and prolidase activities in men with erectile dysfunction.
Comprehensive in-silico prediction of damage associated SNPs in Human Prolidase gene.
Evaluation of Prolidase Activity, Oxidative Stress and Antioxidant Enzyme Levels in Testicular and Penile Tissues after Human Chorionic Gonadotropin Treatment in Rats by Predicting Infertility and Erectile Dysfunction.
The Association of Serum Prolidase Activity and Erectile Dysfunction.
Esophageal Squamous Cell Carcinoma
Serum prolidase activity, total oxidant/antioxidant, and nitric oxide levels in patients with esophageal squamous cell carcinoma.
Exanthema
Prolidase deficiency: it looks like systemic lupus erythematosus but it is not.
Rare diseases that mimic Systemic Lupus Erythematosus (Lupus mimickers).
Exfoliation Syndrome
Serum prolidase activity and oxidative stress in patients with pseudoexfoliation syndrome.
Familial Mediterranean Fever
High prolidase levels in patients with Familial Mediterranean Fever (FMF).
Fatty Liver
Diagnostic Value of Serum Prolidase Enzyme Activity to Predict the Liver Histological Lesions in Non-alcoholic Fatty Liver Disease: A Surrogate Marker to Distinguish Steatohepatitis from Simple Steatosis.
Serum prolidase enzyme activity and its relation to histopathological findings in patients with non-alcoholic steatohepatitis.
Fibromyalgia
Serum prolidase enzyme activity and oxidative status in patients with fibromyalgia.
Fibrosarcoma
Activity of lysosomal and nonlysosomal proteases of fibrosarcoma induced by methylcholanthrene.
Foot Ulcer
A Rare Cause of Lower Extremity Ulcers: Prolidase Deficiency.
Serum prolidase activity in diabetic foot ulcers.
Genetic Diseases, Inborn
Collagen biosynthesis anomalies in prolidase deficiency: effect of glycyl-L-proline on the degradation of newly synthesized collagen.
Inborn errors of proline metabolism.
Macrophage Activation Syndrome in a Patient with Prolidase Deficiency: a Rare Genetic Disorder Associated with Elevated IgE and Lupus-Like Syndrome.
Prolidase deficiency among an Israeli population: prenatal diagnosis in a genetic disorder with uncertain prognosis.
Prolidase Deficiency in a Mexican-American Patient Identified by Array CGH Reveals a Novel and the Largest PEPD Gene Deletion.
Prolidase deficiency: dento-facial aspects in a paediatric patient.
Therapeutic apheresis exchange in two patients with prolidase deficiency.
Granuloma
Serum prolidase level in patients with brucellosis and its possible relationship with pathogenesis of the disease: a prospective observational study
Graves Disease
Serum prolidase levels in Graves' disease without ophthalmopathy and its association with oxidative status.
Heart Diseases
Plasma prolidase activity: a possible index of collagen catabolism in chronic liver disease.
Hemangioma
Leg ulcers in childhood: A multicenter study in France.
[Particular aspects of ulcers in children]
Hemoglobinopathies
[Particular aspects of ulcers in children]
Hemorrhagic Stroke
Serum prolidase enzyme activity and oxidative stress levels in patients with acute hemorrhagic stroke.
Hepatitis B
Does prolidase indicate worsening of hepatitis B infection?
Serum prolidase activity and oxidant¿antioxidant status in children with chronic hepatitis B virus infection.
Hepatitis B, Chronic
Does prolidase indicate worsening of hepatitis B infection?
Serum prolidase activity and oxidant¿antioxidant status in children with chronic hepatitis B virus infection.
Hepatitis C, Chronic
Prolidase and oxidative stress in chronic hepatitis C.
Hepatitis, Alcoholic
Plasma prolidase and prolinase activity in alcoholic liver disease.
Hepatitis, Chronic
Determination of prolinase activity in plasma. Application to liver disease and its relation with prolidase activity.
Histiocytic Necrotizing Lymphadenitis
Rare diseases that mimic Systemic Lupus Erythematosus (Lupus mimickers).
Hypersensitivity
Differential Diagnosis of Genetic Disorders Associated with Moderate to Severe Refractory Eczema and Elevated Immunoglobulin E.
Hypertension
Serum prolidase activity in patients with hypertension and its relation with left ventricular hypertrophy.
Serum prolidase activity in patients with left ventricular diastolic dysfunction.
Hypertrophy, Left Ventricular
Serum prolidase activity in patients with hypertension and its relation with left ventricular hypertrophy.
Hypoparathyroidism
[A case of prolidase deficiency with leg ulcers, hypoparathyroidism and imidodipeptiduria (author's transl)]
Infections
A homozygous missense mutation in PEPD encoding peptidase D causes prolidase deficiency associated with hyper-IgE syndrome.
A photographic essay of prolidase deficiency.
A Rare Cause of Lower Extremity Ulcers: Prolidase Deficiency.
Activity of prolidase isoenzymes in the rat brain: Subcellular and regional distribution during development.
Amelioration of prolidase deficiency in fibroblasts using adenovirus mediated gene transfer.
Clinical Genetics of Prolidase Deficiency: An Updated Review.
Does prolidase indicate worsening of hepatitis B infection?
Four novel PEPD alleles causing prolidase deficiency.
Human recombinant prolidase from eukaryotic and prokaryotic sources. Expression, purification, characterization and long-term stability studies.
Identifying the structure of the active sites of human recombinant prolidase.
Prolidase and oxidative stress in chronic hepatitis C.
Prolidase deficiency associated with pathologic myopia.
Prolidase deficiency in cultured human fibroblasts: biochemical pathology and iminodipeptide-enhanced growth.
Prolidase deficiency in two dermatological patients in western Sicily.
Prolidase deficiency with hyperimmunoglobulin E: a case report.
Prolidase deficiency: a multisystemic hereditary disorder.
Prolidase deficiency: dento-facial aspects in a paediatric patient.
Quantitative analysis of the natural history of prolidase deficiency: description of 17 families and systematic review of published cases.
Serum prolidase activity and oxidative status in Helicobacter pylori infection.
Serum prolidase activity, oxidant and antioxidant status in nonulcer dyspepsia and healthy volunteers.
Solitary Mastocytoma of the Eyelid in an Adult Patient With Prolidase Deficiency.
The role of prolidase as an enzyme participating in the metabolism of collagen.
Topical tacrolimus therapy in the management of lower extremity ulcers due to prolidase deficiency.
[Septic shock originating with a skin infection in a patient with prolidase deficiency].
Infertility
Evaluation of Prolidase Activity, Oxidative Stress and Antioxidant Enzyme Levels in Testicular and Penile Tissues after Human Chorionic Gonadotropin Treatment in Rats by Predicting Infertility and Erectile Dysfunction.
Prolidase enzyme activity in varicose venous walls related to sperm count in patients with varicocele.
Role of prolidase activity and oxidative stress biomarkers in unexplained infertility.
Inflammatory Bowel Diseases
Prolidase Deficiency in Very Early Onset Inflammatory Bowel Disease (VEO-IBD).
Influenza, Human
Prolidase Is Required for Early Trafficking Events during Influenza A Virus Entry.
Intellectual Disability
A Case Of 13-Year-Old Girl With Prolidase Deficiency.
A Case of Prolidase Deficiency Accompanying Leg Ulcers.
A homozygous missense mutation in PEPD encoding peptidase D causes prolidase deficiency associated with hyper-IgE syndrome.
A Rare Cause of Lower Extremity Ulcers: Prolidase Deficiency.
A single nucleotide change in the prolidase gene in fibroblasts from two patients with polypeptide positive prolidase deficiency. Expression of the mutant enzyme in NIH 3T3 cells.
Activity of prolidase isoenzymes in the rat brain: Subcellular and regional distribution during development.
Amelioration of prolidase deficiency in fibroblasts using adenovirus mediated gene transfer.
Brain morphological defects in prolidase deficient mice: first report.
Characterization of a new PEPD allele causing prolidase deficiency in two unrelated patients: natural-occurrent mutations as a tool to investigate structure-function relationship.
Clinical Genetics of Prolidase Deficiency: An Updated Review.
Four novel PEPD alleles causing prolidase deficiency.
Functional and molecular characterization of rat intestinal prolidase.
Human recombinant prolidase from eukaryotic and prokaryotic sources. Expression, purification, characterization and long-term stability studies.
Identifying the structure of the active sites of human recombinant prolidase.
In situ activation of human erythrocyte prolidase: potential for enzyme replacement therapy in prolidase deficiency.
Inborn errors of proline metabolism.
INFLAMMATORY BOWEL DISEASE-LIKE PHENOTYPE IN A YOUNG GIRL WITH PROLIDASE DEFICIENCY: A NEW SPECTRUM OF CLINICAL MANIFESTATION.
Molecular defect in siblings with prolidase deficiency and absence or presence of clinical symptoms. A 0.8-kb deletion with breakpoints at the short, direct repeat in the PEPD gene and synthesis of abnormal messenger RNA and inactive polypeptide.
Mutation analysis of five new patients affected by prolidase deficiency: the lack of enzyme activity causes necrosis-like cell death in cultured fibroblasts.
Plasma Prolidase Activity and Oxidative Stress in Patients with Parkinson's Disease.
Prolidase deficiency associated with pathologic myopia.
Prolidase deficiency in cultured human fibroblasts: biochemical pathology and iminodipeptide-enhanced growth.
Prolidase deficiency in two dermatological patients in western Sicily.
Prolidase deficiency with hyperimmunoglobulin E: a case report.
Prolidase deficiency: a multisystemic hereditary disorder.
Prolidase deficiency: dento-facial aspects in a paediatric patient.
Prolidase isoenzymes in the rat: their organ distribution, developmental change and specific inhibitors.
The role of prolidase as an enzyme participating in the metabolism of collagen.
Topical tacrolimus therapy in the management of lower extremity ulcers due to prolidase deficiency.
Ulcus cruris associated with prolidase deficiency.
[Hereditary prolidase deficiency. Contribution to differential therapy refractory leg ulcer diagnosis]
Job Syndrome
A homozygous missense mutation in PEPD encoding peptidase D causes prolidase deficiency associated with hyper-IgE syndrome.
Joint Dislocations
Ulcus cruris associated with prolidase deficiency.
Joint Instability
Evaluation of antioxidative/oxidative status and prolidase parameters in cases of inguinal hernia with joint hypermobility syndrome.
Is joint hypermobility important in prepubertal children?
Serum prolidase activity in benign joint hypermobility syndrome.
Keloid
Elevated prolidase activity in keloids: correlation with type I collagen turnover.
Keratoconus
Systemic Prolidase Activity and Oxidative Stress in Keratoconus.
Tear Film and Serum Prolidase Activity and Oxidative Stress in Patients With Keratoconus.
Kidney Failure, Chronic
Serum prolidase activity and oxidative stress in diabetic nephropathy and end stage renal disease: a correlative study with glucose and creatinine.
The role of prolidase activity in the diagnosis of uremic bone disease.
Leg Ulcer
A Case of Prolidase Deficiency Accompanying Leg Ulcers.
An autopsy case of prolidase deficiency.
Effect of topical application of glycine and proline on recalcitrant leg ulcers of prolidase deficiency.
Hyperbaric oxygen therapy in the management of severe leg ulcers from prolidase deficiency.
Leg ulcers in childhood: A multicenter study in France.
Leg ulcers secondary to prolidase deficiency.
Prolidase deficiency in two siblings with chronic leg ulcerations. Clinical, biochemical, and morphologic aspects.
Prolidase deficiency: the use of topical proline for treatment of leg ulcers.
Refractory leg ulcers in prolidase deficiency with antiphospholipid antibody positivity responding to aspirin-hydroxychloroquine-vitamin C combination therapy.
Systemic lupus erythematosus-like disease in a 6-year-old boy with prolidase deficiency.
The effects of serum iminodipeptides and prednisolone on superoxide generation and tyrosyl phosphorylation of proteins in neutrophils from a patient with prolidase deficiency.
Ulcus cruris associated with prolidase deficiency.
[A case of prolidase deficiency with leg ulcers, hypoparathyroidism and imidodipeptiduria (author's transl)]
[Chronic leg ulcer in children with prolidase deficiency]
[Hereditary prolidase deficiency in 2 sisters with therapy-resistant leg ulcers]
[Hereditary prolidase deficiency. Contribution to differential therapy refractory leg ulcer diagnosis]
[Leg ulcers and prolidase deficiency]
[Leg ulcers caused by prolidase deficiency]
[Leg ulcers occuring at puberty seemingly following a deficity of prolidase]
[Particular aspects of ulcers in children]
Legg-Calve-Perthes Disease
Serum prolidase activity and oxidative-antioxidative status in Legg-Calve-Perthes disease.
Leiomyoma
Oxidative stress and prolidase activity in women with uterine fibroids.
[Integrins and prolidase activity in uterine leiomyoma during tumor growth]
Lichen Planus, Oral
Evaluation of prolidase activity and oxidative stress in patients with oral lichen planus and oral lichenoid contact reactions.
Liver Abscess
Plasma prolidase activity as a possible diagnostic index of chronic hepatic abscess in cattle.
Liver Cirrhosis
Effects of bicyclol on dimethylnitrosamine-induced liver fibrosis in mice and its mechanism of action.
Evaluation of the Utility of Serum Prolidase as a Marker for Liver Fibrosis.
Plasma prolidase in the rat: no index of liver fibrosis.
Plasma prolidase may be an index of liver fibrosis in the rat.
Serum prolidase enzyme activity and its relation to histopathological findings in patients with non-alcoholic steatohepatitis.
Liver Diseases
Determination of prolinase activity in plasma. Application to liver disease and its relation with prolidase activity.
Diagnostic Value of Serum Prolidase Enzyme Activity to Predict the Liver Histological Lesions in Non-alcoholic Fatty Liver Disease: A Surrogate Marker to Distinguish Steatohepatitis from Simple Steatosis.
Plasma prolidase activity: a possible index of collagen catabolism in chronic liver disease.
Liver Diseases, Alcoholic
Plasma prolidase and prolinase activity in alcoholic liver disease.
Loeys-Dietz Syndrome
Differential Diagnosis of Genetic Disorders Associated with Moderate to Severe Refractory Eczema and Elevated Immunoglobulin E.
Lung Diseases
Chronic lung disease and cystic fibrosis phenotype in prolidase deficiency: a newly recognized association.
Lupus Erythematosus, Systemic
Prolidase deficiency and systemic lupus erythematosus.
Prolidase deficiency associated with systemic lupus erythematosus (SLE): single site experience and literature review.
Prolidase deficiency: it looks like systemic lupus erythematosus but it is not.
Systemic lupus erythematosus-like disease in a 6-year-old boy with prolidase deficiency.
Lupus Nephritis
Induction therapy with rituximab for lupus nephritis due to prolidase deficiency.
Lymphatic Metastasis
Prolidase activity and oxidative stress in patients with breast carcinoma A prospective randomized case-controlled study.
Lymphoma
Proteomics of canine lymphoma identifies potential cancer-specific protein markers.
Lymphoma, T-Cell
Rare diseases that mimic Systemic Lupus Erythematosus (Lupus mimickers).
Macrophage Activation Syndrome
Macrophage Activation Syndrome in a Patient with Prolidase Deficiency: a Rare Genetic Disorder Associated with Elevated IgE and Lupus-Like Syndrome.
Malabsorption Syndromes
The activities of alanine aminopeptidase, leucine aminopeptidase, proline dipeptidase and prolyl dipeptidase in the mucosa of the small intestine. Investigations on normal children and patients with the malabsorption syndrome.
Mastocytoma
Solitary Mastocytoma of the Eyelid in an Adult Patient With Prolidase Deficiency.
Melanoma
Chapter 3 biotechnological applications of recombinant microbial prolidases.
Human prolidase and prolidase deficiency: an overview on the characterization of the enzyme involved in proline recycling and on the effects of its mutations.
Prolidase, a potential enzyme target for melanoma: design of proline-containing dipeptide-like prodrugs.
Proline prodrug of melphalan targeted to prolidase, a prodrug activating enzyme overexpressed in melanoma.
Metabolic Syndrome
Serum prolidase activity is associated with non-diabetic metabolic syndrome.
Metabolism, Inborn Errors
Population screening in a Druze community: the challenge and the reward.
[Particular aspects of ulcers in children]
Microvascular Angina
Serum prolidase activity in patients with cardiac syndrome X.
Mitral Valve Stenosis
Association of prolidase activity, oxidative parameters, and presence of atrial fibrillation in patients with mitral stenosis.
Myocardial Infarction
Circulating Prolidase Activity in Patients with Myocardial Infarction.
Myopia
Prolidase deficiency associated with pathologic myopia.
Myotonic Dystrophy
Genetic linkage between the loci for myotonic dystrophy and peptidase D.
Nasal Polyps
Prolidase activity and oxidative stress parameters in patients with nasal polyps.
Neoplasm Metastasis
Current Insights into the Role of HIF-1 in Cutaneous Wound Healing.
Prolidase activity and oxidative stress in patients with breast carcinoma A prospective randomized case-controlled study.
Serum prolidase I activity and some bone metabolic markers in patients with breast cancer: in relation to menopausal status.
Neoplasms
A recombinant human protein targeting HER2 overcomes drug resistance in HER2-positive breast cancer.
Activity of lysosomal and nonlysosomal proteases and contents of protein and its degradation products in the blood serum of rats with fibrosarcoma induced by methylcholanthrene.
Assessment of preoperative serum prolidase activity in epithelial ovarian cancer.
Assessment of the correlation between serum prolidase and alpha-fetoprotein levels in patients with hepatocellular carcinoma.
Chapter 3 biotechnological applications of recombinant microbial prolidases.
Collagen metabolism as a regulator of proline dehydrogenase/proline oxidase-dependent apoptosis/autophagy.
Comprehensive in-silico prediction of damage associated SNPs in Human Prolidase gene.
Current Insights into the Role of HIF-1 in Cutaneous Wound Healing.
Dual inhibition of ErbB1 and ErbB2 in cancer by recombinant human prolidase mutant hPEPD-G278D.
Effects of bicyclol on dimethylnitrosamine-induced liver fibrosis in mice and its mechanism of action.
Inhibition of ERBB2-overexpressing Tumors by Recombinant Human Prolidase and Its Enzymatically Inactive Mutant.
Prolidase - A protein with many faces.
Prolidase activity and beta 1 integrin expression in moderately and poorly differentiated lung adenocarcinomas.
Prolidase activity and oxidative stress in patients with breast carcinoma A prospective randomized case-controlled study.
Prolidase, a potential enzyme target for melanoma: design of proline-containing dipeptide-like prodrugs.
Proline prodrug of melphalan targeted to prolidase, a prodrug activating enzyme overexpressed in melanoma.
Serum prolidase activity, oxidative stress, and antioxidant enzyme levels in patients with renal cell carcinoma.
Serum prolidase I activity and some bone metabolic markers in patients with breast cancer: in relation to menopausal status.
The decrease in prolidase activity in myeloproliferative neoplasms.
The effect of estrogen on prolidase-dependent regulation of HIF-1? expression in breast cancer cells.
The Prolidase Activity, Oxidative Stress, and Nitric Oxide Levels of Bladder Tissues with or Without Tumor in Patients with Bladder Cancer.
[Integrins and prolidase activity in uterine leiomyoma during tumor growth]
Netherton Syndrome
Differential Diagnosis of Genetic Disorders Associated with Moderate to Severe Refractory Eczema and Elevated Immunoglobulin E.
Neural Tube Defects
Amniotic fluid prolidase activity and oxidative status in neural tube defects.
[Particular aspects of ulcers in children]
Non-alcoholic Fatty Liver Disease
Diagnostic Value of Serum Prolidase Enzyme Activity to Predict the Liver Histological Lesions in Non-alcoholic Fatty Liver Disease: A Surrogate Marker to Distinguish Steatohepatitis from Simple Steatosis.
Serum prolidase enzyme activity and its relation to histopathological findings in patients with non-alcoholic steatohepatitis.
Obstetric Labor, Premature
Vaginal hydrolytic enzymes, immunoglobulin A against Gardnerella vaginalis toxin, and risk of early preterm birth among women in preterm labor with bacterial vaginosis or intermediate flora.
Osteoarthritis
Prolidase expression in knee osteoarthritis and healthy controls: Observational study.
Osteoarthritis, Hip
Protein metabolism in the synovial membrane in the hip osteoarthritis.
Osteoarthritis, Knee
Corrigendum to "The Overexpression of NALP3 Inflammasome in Knee Osteoarthritis Is Associated with Synovial Membrane Prolidase and NADPH Oxidase 2".
Evaluation of prolidase activity and oxidative status in patients with knee osteoarthritis: relationships with radiographic severity and clinical parameters.
Increased oxidative stress and its relation with collagen metabolism in knee osteoarthritis.
Prolidase expression in knee osteoarthritis and healthy controls: Observational study.
The Overexpression of NALP3 Inflammasome in Knee Osteoarthritis Is Associated with Synovial Membrane Prolidase and NADPH Oxidase 2.
Osteogenesis Imperfecta
Defects of type I procollagen metabolism correlated with decrease of prolidase activity in a case of lethal osteogenesis imperfecta.
Phenotype variability in a daughter and father with mild osteogenesis imperfecta correlated with collagen and prolidase levels in cultured skin fibroblasts.
Osteoporosis
Oxidative Stress And Prolidase Enzyme Activity In The Pathogenesis Of Primary Varicose Veins.
Serum prolidase activity as a marker of osteoporosis in type 2 diabetes mellitus.
Serum prolidase activity in postmenopausal osteoporosis.
Osteoporosis, Postmenopausal
Correlations of serum prolidase activity between bone turnover markers and mineral density in postmenopausal osteoporosis.
Serum prolidase activity in postmenopausal osteoporosis.
Pancreatic Diseases
Prolidase activity disregulation in chronic pancreatitis and pancreatic cancer.
Pancreatic Neoplasms
Prolidase activity disregulation in chronic pancreatitis and pancreatic cancer.
Pancreatitis
Prolidase activity disregulation in chronic pancreatitis and pancreatic cancer.
The value of prolidase enzyme in rats with experimentally induced mild and severe pancreatitis.
Pancreatitis, Chronic
Prolidase activity disregulation in chronic pancreatitis and pancreatic cancer.
Parkinson Disease
Plasma Prolidase Activity and Oxidative Stress in Patients with Parkinson's Disease.
Persistent Infection
A Case of Prolidase Deficiency Accompanying Leg Ulcers.
INFLAMMATORY BOWEL DISEASE-LIKE PHENOTYPE IN A YOUNG GIRL WITH PROLIDASE DEFICIENCY: A NEW SPECTRUM OF CLINICAL MANIFESTATION.
Ulcus cruris associated with prolidase deficiency.
Pleural Effusion
Prolidase activity in serum and pleural fluids in patients with tuberculous pleural effusion [correction of effussion].
Pleurisy
Prolidase activity in serum and pleural fluids in patients with tuberculous pleural effusion [correction of effussion].
Pneumonia, Pneumococcal
An Adult with Recurrent Severe Pneumococcal Pneumonia Secondary to Prolidase Deficiency.
Polycystic Ovary Syndrome
Increased Prolidase Activity and Oxidative Stress in PCOS.
Plasma prolidase levels as a biomarker for polycystic ovary syndrome.
The role of rs267606943 polymorphism in the prolidase gene and plasma prolidase in polycystic ovary syndrome.
Pre-Eclampsia
Is there any role of prolidase enzyme activity in the etiology of preeclampsia?
Pregnancy, Ectopic
Oxidative status and serum prolidase activity in tubal ectopic pregnancy.
Premature Birth
Combination of vaginal pH with vaginal sialidase and prolidase activities for prediction of low birth weight and preterm birth.
Vaginal hydrolytic enzymes, immunoglobulin A against Gardnerella vaginalis toxin, and risk of early preterm birth among women in preterm labor with bacterial vaginosis or intermediate flora.
Pressure Ulcer
Leg ulcers in childhood: A multicenter study in France.
Primary Immunodeficiency Diseases
Flavivirus Antagonism of Type I Interferon Signaling Reveals Prolidase as a Regulator of IFNAR1 Surface Expression.
Rare diseases that mimic Systemic Lupus Erythematosus (Lupus mimickers).
Prolidase Deficiency
A broad spectrum of developmental delay in a large cohort of prolidase deficiency patients demonstrates marked interfamilial and intrafamilial phenotypic variability.
A Case Of 13-Year-Old Girl With Prolidase Deficiency.
A Case of Prolidase Deficiency Accompanying Leg Ulcers.
A homozygous missense mutation in PEPD encoding peptidase D causes prolidase deficiency associated with hyper-IgE syndrome.
A nonsense mutation of PEPD in four Amish children with prolidase deficiency.
A Novel Manifestation of Prolidase Deficiency in a Toddler Diagnosed With Very-early-onset Crohn Disease.
A novel nonsense mutation of the PEPD gene in a Japanese patient with prolidase deficiency.
A photographic essay of prolidase deficiency.
A prolidase deficiency in man with iminopeptiduria.
A rare case of prolidase deficiency with situs inversus totalis, identified by a novel mutation in the PEPD gene.
A rare cause of cutaneous ulceration: Prolidase deficiency.
A Rare Cause of Lower Extremity Ulcers: Prolidase Deficiency.
A single nucleotide change in the prolidase gene in fibroblasts from two patients with polypeptide positive prolidase deficiency. Expression of the mutant enzyme in NIH 3T3 cells.
Abnormal mRNA and inactive polypeptide in a patient with prolidase deficiency.
Activity of prolidase isoenzymes in the rat brain: Subcellular and regional distribution during development.
Amelioration of prolidase deficiency in fibroblasts using adenovirus mediated gene transfer.
An Adult with Recurrent Severe Pneumococcal Pneumonia Secondary to Prolidase Deficiency.
An autopsy case of prolidase deficiency.
Angiopathic pathogenesis of clinical manifestations in prolidase deficiency.
Autosomal recessive prolidase deficiency. Three patients with recalcitrant ulcers.
Biochemical basis of prolidase deficiency. Polypeptide and RNA phenotypes and the relation to clinical phenotypes.
Biochemical investigations on prolidase and prolinase in erythrocytes from patients with prolidase deficiency.
Biochemical studies on prolidase in sera from control, patients with prolidase deficiency and their mother.
Biodegradable microspheres for prolidase delivery to human cultured fibroblasts.
Blood transfusions in the therapy of a case of prolidase deficiency.
Bound hydroxyproline excretion following gelatin loading in prolidase deficiency.
Brain morphological defects in prolidase deficient mice: first report.
Cell density affects prolidase and prolinase activity and intracellular amino acid levels in cultured human cells.
Chapter 3 biotechnological applications of recombinant microbial prolidases.
Characteristics and partial purification of prolidase and prolinase from leukocytes of a normal human and a patient with prolidase deficiency.
Characteristics of prolidase from the erythrocytes of normal humans and patients with prolidase deficiency and their mother.
Characteristics of prolinase against various iminodipeptides in erythrocyte lysates from a normal human and a patient with prolidase deficiency.
Characterization of a new PEPD allele causing prolidase deficiency in two unrelated patients: natural-occurrent mutations as a tool to investigate structure-function relationship.
Characterization of prolidase activity in erythrocytes from a patient with prolidase deficiency: comparison with prolidase I and II purified from normal human erythrocytes.
Characterization of prolidase I and II from erythrocytes of a control, a patient with prolidase deficiency and her mother.
Characterization of prolidase I and II purified from normal human erythrocytes: comparison with prolidase in erythrocytes from a patient with prolidase deficiency.
Chronic leg ulcerations resembling vasculitis in two siblings with prolidase deficiency.
Chronic lung disease and cystic fibrosis phenotype in prolidase deficiency: a newly recognized association.
Clinical and biochemical characteristics of prolidase deficiency in siblings.
Clinical Genetics of Prolidase Deficiency: An Updated Review.
Collagen biosynthesis anomalies in prolidase deficiency: effect of glycyl-L-proline on the degradation of newly synthesized collagen.
Congenital expression of prolidase defect in prolidase deficiency.
Corticosteroid treatment of prolidase deficiency skin lesions by inhibiting iminodipeptide-primed neutrophil superoxide generation.
Current Understanding of the Emerging Role of Prolidase in Cellular Metabolism.
Deduced amino acid sequence of human prolidase and molecular analyses of prolidase deficiency.
Determination of prolidase activity using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.
Developmental cardiac hypertrophy in a mouse model of prolidase deficiency.
Different effects of sulfur amino acids on prolidase and prolinase activity in normal and prolidase-deficient human erythrocytes.
Differential Diagnosis of Genetic Disorders Associated with Moderate to Severe Refractory Eczema and Elevated Immunoglobulin E.
Effect of different surfactants on the separation by micellar electrokinetic chromatography of a complex mixture of dipeptides in urine of prolidase-deficient patients.
Effect of topical application of glycine and proline on recalcitrant leg ulcers of prolidase deficiency.
Effects of amino acids and its metabolites on prolidase activity against various iminodipeptides in erythrocytes from normal human and a patient with prolidase deficiency.
Enzyme loaded biodegradable microspheres in vitro ex vivo evaluation.
Epidermolysis bullosa simplex: expression of gelatinase activity in cultured human skin fibroblasts.
Ex vivo evaluation of prolidase loaded chitosan nanoparticles for the enzyme replacement therapy.
Expression and molecular analysis of mutations in prolidase deficiency.
Extracellular matrix and HIF-1 signaling: the role of prolidase.
Flavivirus Antagonism of Type I Interferon Signaling Reveals Prolidase as a Regulator of IFNAR1 Surface Expression.
Four novel PEPD alleles causing prolidase deficiency.
Further studies on a patient with iminodipeptiduria: a probable case of prolidase deficiency.
Human erythrocyte prolidase and prolidase deficiency.
Human kidney prolidase--purification, preincubation properties and immunological reactivity.
Human prolidase and prolidase deficiency: an overview on the characterization of the enzyme involved in proline recycling and on the effects of its mutations.
Human recombinant prolidase from eukaryotic and prokaryotic sources. Expression, purification, characterization and long-term stability studies.
Hyperbaric oxygen therapy in the management of severe leg ulcers from prolidase deficiency.
Identification and analysis of a novel mutation in PEPD gene in two Kashmiri siblings with prolidase enzyme deficiency.
Iminopeptiduria, skin ulcerations, and edema in a boy with prolidase deficiency.
Immune function in prolidase deficiency.
Immunochemical analyses of prolidase deficiency sera.
Immunochemical analysis of prolidase deficiency and molecular cloning of cDNA for prolidase of human liver.
Immunochemical studies of human prolidase with monoclonal and polyclonal antibodies: absence of the subunit of prolidase in erythrocytes from a patient with prolidase deficiency.
Improved prolidase activity assay allowed enzyme kinetic characterization and faster prolidase deficiency diagnosis.
In situ activation of human erythrocyte prolidase: potential for enzyme replacement therapy in prolidase deficiency.
In-vitro responses to ascorbate and manganese in fibroblasts from a patient with prolidase deficiency and iminodipeptiduria: cell growth, prolidase activity and collagen metabolism.
Inborn errors of proline metabolism.
Increased manganese content and reduced arginase activity in erythrocytes of a patient with prolidase deficiency (iminodipeptiduria).
Induction therapy with rituximab for lupus nephritis due to prolidase deficiency.
INFLAMMATORY BOWEL DISEASE-LIKE PHENOTYPE IN A YOUNG GIRL WITH PROLIDASE DEFICIENCY: A NEW SPECTRUM OF CLINICAL MANIFESTATION.
Intracellular delivery of liposome-encapsulated prolidase in cultured fibroblasts from prolidase-deficient patients.
Kinetic and structural evidences on human prolidase pathological mutants suggest strategies for enzyme functional rescue.
Lack of prolidase causes a bone phenotype both in human and in mouse.
Leg ulcers in childhood: A multicenter study in France.
Leg ulcers secondary to prolidase deficiency.
Liquid chromatography-mass spectrometry for simultaneous analyses of iminodipeptides containing an N-terminal or a C-terminal proline.
Liquid chromatography-mass spectrometry for the qualitative analyses of iminodipeptides in the urine of patients with prolidase deficiency.
Macrophage Activation Syndrome in a Patient with Prolidase Deficiency: a Rare Genetic Disorder Associated with Elevated IgE and Lupus-Like Syndrome.
Massive Splenomegaly Secondary to Prolidase Deficiency.
Measurement of iminodipeptides in the serum of patients with prolidase deficiency using liquid chromatography-mass spectrometry.
Mild, late-onset prolidase deficiency: another Italian case.
Molecular basis of prolidase (peptidase D) deficiency.
Molecular characterisation of six patients with prolidase deficiency: identification of the first small duplication in the prolidase gene and of a mutation generating symptomatic and asymptomatic outcomes within the same family.
Molecular defect in siblings with prolidase deficiency and absence or presence of clinical symptoms. A 0.8-kb deletion with breakpoints at the short, direct repeat in the PEPD gene and synthesis of abnormal messenger RNA and inactive polypeptide.
Mutation analysis of five new patients affected by prolidase deficiency: the lack of enzyme activity causes necrosis-like cell death in cultured fibroblasts.
N-benzyloxycarbonyl-L-proline: an in vitro and in vivo inhibitor of prolidase.
Nasal reconstruction in a patient with prolidase deficiency syndrome.
Normal hydroxylation of proline in collagen synthesized by skin fibroblasts from a patient with prolidase deficiency.
Normal production, nature, and extent of intracellular degradation of newly synthesized collagen in fibroblasts from a patient with prolidase deficiency.
Optimization of a capillary electrophoretic method to detect and quantify the Gly-Pro dipeptide in complex matrices from long term cultured prolidase deficiency fibroblasts.
Partial Rescue of Biochemical Parameters After Hematopoietic Stem Cell Transplantation in a Patient with Prolidase Deficiency Due to Two Novel PEPD Mutations.
Plasma Prolidase Activity and Oxidative Stress in Patients with Parkinson's Disease.
Plasma prolidase and prolinase activity in prolidase deficiency.
Polidistrectual videocapillaroscopic evaluation in a patient with prolidase deficiency.
Population screening in a Druze community: the challenge and the reward.
Presence in human cells and tissues of two prolidases and their alteration in prolidase deficiency.
Prolidase - A protein with many faces.
Prolidase and prolidase deficiency.
Prolidase deficiency among an Israeli population: prenatal diagnosis in a genetic disorder with uncertain prognosis.
Prolidase deficiency and systemic lupus erythematosus.
Prolidase deficiency and the biochemical assays used in its diagnosis.
Prolidase deficiency associated with hemoglobin O trait and microcytic anemia.
Prolidase deficiency associated with pathologic myopia.
Prolidase deficiency associated with systemic lupus erythematosus (SLE): single site experience and literature review.
Prolidase deficiency breaks tolerance to lupus-associated antigens.
Prolidase deficiency diagnosed by 1H NMR spectroscopy of urine.
Prolidase deficiency diagnosed by whole exome sequencing in a child with pulmonary capillaritis.
Prolidase Deficiency in a Mexican-American Patient Identified by Array CGH Reveals a Novel and the Largest PEPD Gene Deletion.
Prolidase deficiency in cultured human fibroblasts: biochemical pathology and iminodipeptide-enhanced growth.
Prolidase deficiency in two dermatological patients in western Sicily.
Prolidase deficiency in two siblings with chronic leg ulcerations. Clinical, biochemical, and morphologic aspects.
Prolidase deficiency in two sisters with recurrent ulcerations of the lower extremities.
Prolidase Deficiency in Very Early Onset Inflammatory Bowel Disease (VEO-IBD).
Prolidase deficiency with hyperimmunoglobulin E: a case report.
Prolidase deficiency with imidodipeptiduria. A familial case with and without clinical symptoms.
Prolidase deficiency with iminodipeptiduria: biochemical investigations and first results of attempted therapy.
Prolidase deficiency.
Prolidase deficiency. A metabolic disorder presenting with dermatologic signs.
Prolidase deficiency: a case report and literature review.
Prolidase deficiency: a multisystemic hereditary disorder.
Prolidase deficiency: a new genetic cause of combined pulmonary fibrosis and emphysema syndrome in the adult.
Prolidase deficiency: a patient without hydroxyproline-containing iminodipeptides in urine.
Prolidase deficiency: a rare aetiology of arthritis.
Prolidase deficiency: an inborn error of metabolism with major dermatological manifestations.
Prolidase deficiency: biochemical classification of alleles.
Prolidase deficiency: biochemical study of erythrocyte and skin fibroblast prolidase activity in Italian patients.
Prolidase deficiency: case reports of two Argentinian brothers.
Prolidase deficiency: characteristics of human skin fibroblast prolidase using colorimetric and fluorimetric assays.
Prolidase deficiency: dento-facial aspects in a paediatric patient.
Prolidase deficiency: detection of cases by a newborn urinary screening programme.
Prolidase deficiency: it looks like systemic lupus erythematosus but it is not.
Prolidase deficiency: its dermatological manifestations and some additional biochemical studies.
Prolidase deficiency: report of a second case with quantitation of the excessively excreted amino acids.
Prolidase deficiency: the use of topical proline for treatment of leg ulcers.
Prolidase enzyme is required for extracellular matrix integrity and impacts on postnatal cerebellar cortex development.
Prolidase function in proline metabolism and its medical and biotechnological applications.
Prolidase isoenzymes in the rat: their organ distribution, developmental change and specific inhibitors.
PROLIDASE: A Review from Discovery to its Role in Health and Disease.
Prolinase activity in prolidase-deficient fibroblasts.
Pulmonary manifestations of prolidase deficiency.
Quantitative analysis of the natural history of prolidase deficiency: description of 17 families and systematic review of published cases.
Quebec neonatal mass urinary screening programme: from micromolecules to macromolecules.
Rare diseases that mimic Systemic Lupus Erythematosus (Lupus mimickers).
Refractory leg ulcers in prolidase deficiency with antiphospholipid antibody positivity responding to aspirin-hydroxychloroquine-vitamin C combination therapy.
Screening method for prolidase deficiency.
Separation of two erythrocyte prolidase isoforms by fast protein liquid chromatography; application to prolidase deficiency.
Site-directed PEGylation as successful approach to improve the enzyme replacement in the case of prolidase.
Solitary Mastocytoma of the Eyelid in an Adult Patient With Prolidase Deficiency.
Spurious Elevation of Multiple Urine Amino Acids by Ion-Exchange Chromatography in Patients with Prolidase Deficiency.
Squamous cell carcinoma of the leg in a patient with prolidase deficiency.
Structural analysis of new compound heterozygous variants in PEPD gene identified in a patient with Prolidase Deficiency diagnosed by exome sequencing.
Structural basis for prolidase deficiency disease mechanisms.
Structural organization of the gene for human prolidase (peptidase D) and demonstration of a partial gene deletion in a patient with prolidase deficiency.
Studies on prolidase deficiency with a possible defect in collagen metabolism.
Substrate specificity and reaction mechanism of human prolidase.
Substrate specificity of manganese-activated prolidase in control and prolidase-deficient cultured skin fibroblasts.
Systemic lupus erythematosus-like disease in a 6-year-old boy with prolidase deficiency.
The "Georgian ulcers": a prolidase deficiency condition?
The effects of serum iminodipeptides and prednisolone on superoxide generation and tyrosyl phosphorylation of proteins in neutrophils from a patient with prolidase deficiency.
The hyper-IgE syndrome is not caused by a microdeletion syndrome.
The role of emerging techniques in the investigation of prolidase deficiency: From diagnosis to the development of a possible therapeutical approach.
The role of prolidase as an enzyme participating in the metabolism of collagen.
The use of liquid chromatography-mass spectrometry for the identification and quantification of urinary iminodipeptides in prolidase deficiency.
Therapeutic apheresis exchange in two patients with prolidase deficiency.
Topical proline therapy in prolidase deficiency.
Topical tacrolimus therapy in the management of lower extremity ulcers due to prolidase deficiency.
Topical treatment of skin ulcers in prolidase deficiency.
Transient beneficial effect of GH replacement therapy and topical GH application on skin ulcers in a boy with prolidase deficiency.
Ulceration in Prolidase Deficiency: Successful Treatment with Anticoagulants.
Ulcus cruris associated with prolidase deficiency.
Use of capillary zone electrophoresis for analysis of imidodipeptides in urine of prolidase-deficient patients.
[A case for diagnosis: skin ulcers and prolidase deficiency]
[A case of prolidase deficiency with leg ulcers, hypoparathyroidism and imidodipeptiduria (author's transl)]
[An inherent prolidase deficiency (author's transl)]
[Chronic leg ulcer in children with prolidase deficiency]
[Effective therapy with a glycine-proline ointment in a patient with recurrent ulcers from prolidase deficiency]
[Hereditary prolidase deficiency in 2 sisters with therapy-resistant leg ulcers]
[Hereditary prolidase deficiency. Contribution to differential therapy refractory leg ulcer diagnosis]
[Leg ulcers and prolidase deficiency]
[Leg ulcers caused by prolidase deficiency]
[Prolidase and manganese deficiency. Apropos of a case: diagnosis and treatment]
[Prolidase deficiency with various clinical conditions including hyper-IgE and multiple lung bulla formation]
[Prolidase deficiency. Apropos of a peculiar case]
[Prolidase deficiency]
Prostatic Hyperplasia
Peripheral mononuclear leukocyte DNA damage, plasma prolidase activity, and oxidative status in patients with benign prostatic hyperplasia.
Prostatic Neoplasms
Evaluation of serum prolidase activity and oxidative stress markers in men with BPH and prostate cancer.
Psoriasis
Prolidase activity in chronic plaque psoriasis patients.
Serum prolidase activity in psoriasis patients.
Serum prolidase may not accurately provide information to clinicians about the psoriasis activity.
Pterygium
Prolidase Enzyme Activity in Conjunctiva and Pterygium Tissues.
Pulmonary Disease, Chronic Obstructive
Prolidase activity dysregulation and its correlation with oxidative-antioxidative status in chronic obstructive pulmonary disease.
The relationships among the levels of oxidative and antioxidative parameters, FEV1 and prolidase activity in COPD.
Pulmonary Fibrosis
Prolidase deficiency: a new genetic cause of combined pulmonary fibrosis and emphysema syndrome in the adult.
Pyoderma
Leg ulcers in childhood: A multicenter study in France.
Pyoderma Gangrenosum
Leg ulcers in childhood: A multicenter study in France.
Respiratory Tract Infections
Characterization of a new PEPD allele causing prolidase deficiency in two unrelated patients: natural-occurrent mutations as a tool to investigate structure-function relationship.
Identifying the structure of the active sites of human recombinant prolidase.
Prolidase deficiency with hyperimmunoglobulin E: a case report.
Prolidase isoenzymes in the rat: their organ distribution, developmental change and specific inhibitors.
Rheumatic Diseases
Serum prolidase activity in ankylosing spondylitis and rheumatoid arthritis.
Systemic lupus erythematosus-like disease in a 6-year-old boy with prolidase deficiency.
Rosacea
Rare diseases that mimic Systemic Lupus Erythematosus (Lupus mimickers).
Schistosomiasis
Circulating enzyme activities of collagen turnover and undulin in patients with various degrees of schistosomiasis and alcoholic liver cirrhosis.
Scleroderma, Systemic
Evaluation of oxidant and antioxidant status and relation with prolidase in systemic sclerosis.
Serum prolidase activity in systemic sclerosis.
Severe Combined Immunodeficiency
Differential Diagnosis of Genetic Disorders Associated with Moderate to Severe Refractory Eczema and Elevated Immunoglobulin E.
Situs Inversus
A rare case of prolidase deficiency with situs inversus totalis, identified by a novel mutation in the PEPD gene.
Skin Ulcer
A Case Of 13-Year-Old Girl With Prolidase Deficiency.
A Case of Prolidase Deficiency Accompanying Leg Ulcers.
A Rare Cause of Lower Extremity Ulcers: Prolidase Deficiency.
Congenital expression of prolidase defect in prolidase deficiency.
Four novel PEPD alleles causing prolidase deficiency.
Inborn errors of proline metabolism.
Prolidase deficiency in cultured human fibroblasts: biochemical pathology and iminodipeptide-enhanced growth.
Prolidase deficiency in two dermatological patients in western Sicily.
Prolidase deficiency: a multisystemic hereditary disorder.
Prolidase deficiency: the use of topical proline for treatment of leg ulcers.
Prolidase enzyme is required for extracellular matrix integrity and impacts on postnatal cerebellar cortex development.
Topical treatment of skin ulcers in prolidase deficiency.
Transient beneficial effect of GH replacement therapy and topical GH application on skin ulcers in a boy with prolidase deficiency.
[A case for diagnosis: skin ulcers and prolidase deficiency]
Sleep Bruxism
Evaluation of the oxidative stress level and serum prolidase activity in patients with sleep bruxism.
Spondylitis, Ankylosing
Serum prolidase activity in ankylosing spondylitis and rheumatoid arthritis.
Serum prolidase level in ankylosing spondylitis: low serum levels as a new potential gold standard biomarker for disease activity.
Starvation
FAK-independent regulation of prolidase activity and collagen biosynthesis in MCF-7 cells.
The promoter region of the Escherichia coli pepD gene: deletion analysis and control by phosphate concentration.
Stomach Neoplasms
Deregulation of collagen metabolism in human stomach cancer.
Potential diagnostic and prognostic significance of plasma prolidase activity in gastric cancer.
Stomatitis, Aphthous
Serum prolidase and oxidative stress levels in patients with recurrent aphthous stomatitis: a prospective, controlled study.
Thyroid Cancer, Papillary
Relationship of hemoxygenase-1 and prolidase enzyme activity with oxidative stress in papillary thyroid cancer.
Thyroid Diseases
Serum prolidase levels in Graves' disease without ophthalmopathy and its association with oxidative status.
Tinnitus
Evaluation of serum prolidase enzyme activity and oxidative stress in patients with tinnitus.
Tuberculosis
Leg ulcers in childhood: A multicenter study in France.
Tuberculosis, Pulmonary
Serum complement C4b, fibronectin, and prolidase are associated with the pathological changes of pulmonary tuberculosis.
Serum prolidase activity in patients with pulmonary tuberculosis.
Urea Cycle Disorders, Inborn
Quebec neonatal mass urinary screening programme: from micromolecules to macromolecules.
Uremia
Prolidase and prolinase activities in the erythrocytes of patients with chronic uremia.
Urinary Bladder Neoplasms
Serum prolidase activity, oxidative stress, and nitric oxide levels in patients with bladder cancer.
The Prolidase Activity, Oxidative Stress, and Nitric Oxide Levels of Bladder Tissues with or Without Tumor in Patients with Bladder Cancer.
Vaginosis, Bacterial
Among pregnant women with bacterial vaginosis, the hydrolytic enzymes sialidase and prolidase are positively associated with interleukin-1beta.
Correlation of local interleukin-8 with immunoglobulin A against Gardnerella vaginalis hemolysin and with prolidase and sialidase levels in women with bacterial vaginosis.
Determination of immunoglobulin A against Gardnerella vaginalis hemolysin, sialidase, and prolidase activities in vaginal fluid: implications for adverse pregnancy outcomes.
Vaginal hydrolytic enzymes, immunoglobulin A against Gardnerella vaginalis toxin, and risk of early preterm birth among women in preterm labor with bacterial vaginosis or intermediate flora.
Varicocele
Prolidase enzyme activity in varicose venous walls related to sperm count in patients with varicocele.
Varicose Veins
Oxidative Stress And Prolidase Enzyme Activity In The Pathogenesis Of Primary Varicose Veins.
Prolidase enzyme activity in varicose venous walls related to sperm count in patients with varicocele.
Vasculitis
Chronic leg ulcerations resembling vasculitis in two siblings with prolidase deficiency.
[Particular aspects of ulcers in children]
Venous Insufficiency
Oxidative Stress And Prolidase Enzyme Activity In The Pathogenesis Of Primary Varicose Veins.
Vertigo
Serum prolidase, malondialdehyde and catalase levels for the evaluation of oxidative stress in patients with peripheral vertigo.
Wasting Syndrome
Differential Diagnosis of Genetic Disorders Associated with Moderate to Severe Refractory Eczema and Elevated Immunoglobulin E.
Wiskott-Aldrich Syndrome
Differential Diagnosis of Genetic Disorders Associated with Moderate to Severe Refractory Eczema and Elevated Immunoglobulin E.
xaa-pro dipeptidase deficiency
A broad spectrum of developmental delay in a large cohort of prolidase deficiency patients demonstrates marked interfamilial and intrafamilial phenotypic variability.
A Case Of 13-Year-Old Girl With Prolidase Deficiency.
A Case of Prolidase Deficiency Accompanying Leg Ulcers.
A homozygous missense mutation in PEPD encoding peptidase D causes prolidase deficiency associated with hyper-IgE syndrome.
A nonsense mutation of PEPD in four Amish children with prolidase deficiency.
A Novel Manifestation of Prolidase Deficiency in a Toddler Diagnosed With Very-early-onset Crohn Disease.
A novel nonsense mutation of the PEPD gene in a Japanese patient with prolidase deficiency.
A photographic essay of prolidase deficiency.
A prolidase deficiency in man with iminopeptiduria.
A rare case of prolidase deficiency with situs inversus totalis, identified by a novel mutation in the PEPD gene.
A rare cause of cutaneous ulceration: Prolidase deficiency.
A Rare Cause of Lower Extremity Ulcers: Prolidase Deficiency.
A single nucleotide change in the prolidase gene in fibroblasts from two patients with polypeptide positive prolidase deficiency. Expression of the mutant enzyme in NIH 3T3 cells.
Abnormal mRNA and inactive polypeptide in a patient with prolidase deficiency.
Activity of prolidase isoenzymes in the rat brain: Subcellular and regional distribution during development.
Amelioration of prolidase deficiency in fibroblasts using adenovirus mediated gene transfer.
An Adult with Recurrent Severe Pneumococcal Pneumonia Secondary to Prolidase Deficiency.
An autopsy case of prolidase deficiency.
Angiopathic pathogenesis of clinical manifestations in prolidase deficiency.
Autosomal recessive prolidase deficiency. Three patients with recalcitrant ulcers.
Biochemical basis of prolidase deficiency. Polypeptide and RNA phenotypes and the relation to clinical phenotypes.
Biochemical investigations on prolidase and prolinase in erythrocytes from patients with prolidase deficiency.
Biochemical studies on prolidase in sera from control, patients with prolidase deficiency and their mother.
Biodegradable microspheres for prolidase delivery to human cultured fibroblasts.
Blood transfusions in the therapy of a case of prolidase deficiency.
Bound hydroxyproline excretion following gelatin loading in prolidase deficiency.
Brain morphological defects in prolidase deficient mice: first report.
Cell density affects prolidase and prolinase activity and intracellular amino acid levels in cultured human cells.
Chapter 3 biotechnological applications of recombinant microbial prolidases.
Characteristics and partial purification of prolidase and prolinase from leukocytes of a normal human and a patient with prolidase deficiency.
Characteristics of prolidase from the erythrocytes of normal humans and patients with prolidase deficiency and their mother.
Characteristics of prolinase against various iminodipeptides in erythrocyte lysates from a normal human and a patient with prolidase deficiency.
Characterization of a new PEPD allele causing prolidase deficiency in two unrelated patients: natural-occurrent mutations as a tool to investigate structure-function relationship.
Characterization of prolidase activity in erythrocytes from a patient with prolidase deficiency: comparison with prolidase I and II purified from normal human erythrocytes.
Characterization of prolidase I and II from erythrocytes of a control, a patient with prolidase deficiency and her mother.
Characterization of prolidase I and II purified from normal human erythrocytes: comparison with prolidase in erythrocytes from a patient with prolidase deficiency.
Chronic leg ulcerations resembling vasculitis in two siblings with prolidase deficiency.
Chronic lung disease and cystic fibrosis phenotype in prolidase deficiency: a newly recognized association.
Clinical and biochemical characteristics of prolidase deficiency in siblings.
Clinical Genetics of Prolidase Deficiency: An Updated Review.
Collagen biosynthesis anomalies in prolidase deficiency: effect of glycyl-L-proline on the degradation of newly synthesized collagen.
Congenital expression of prolidase defect in prolidase deficiency.
Corticosteroid treatment of prolidase deficiency skin lesions by inhibiting iminodipeptide-primed neutrophil superoxide generation.
Current Understanding of the Emerging Role of Prolidase in Cellular Metabolism.
Deduced amino acid sequence of human prolidase and molecular analyses of prolidase deficiency.
Determination of prolidase activity using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.
Developmental cardiac hypertrophy in a mouse model of prolidase deficiency.
Different effects of sulfur amino acids on prolidase and prolinase activity in normal and prolidase-deficient human erythrocytes.
Differential Diagnosis of Genetic Disorders Associated with Moderate to Severe Refractory Eczema and Elevated Immunoglobulin E.
Effect of different surfactants on the separation by micellar electrokinetic chromatography of a complex mixture of dipeptides in urine of prolidase-deficient patients.
Effect of topical application of glycine and proline on recalcitrant leg ulcers of prolidase deficiency.
Effects of amino acids and its metabolites on prolidase activity against various iminodipeptides in erythrocytes from normal human and a patient with prolidase deficiency.
Enzyme loaded biodegradable microspheres in vitro ex vivo evaluation.
Epidermolysis bullosa simplex: expression of gelatinase activity in cultured human skin fibroblasts.
Ex vivo evaluation of prolidase loaded chitosan nanoparticles for the enzyme replacement therapy.
Expression and molecular analysis of mutations in prolidase deficiency.
Extracellular matrix and HIF-1 signaling: the role of prolidase.
Flavivirus Antagonism of Type I Interferon Signaling Reveals Prolidase as a Regulator of IFNAR1 Surface Expression.
Four novel PEPD alleles causing prolidase deficiency.
Further studies on a patient with iminodipeptiduria: a probable case of prolidase deficiency.
Human erythrocyte prolidase and prolidase deficiency.
Human kidney prolidase--purification, preincubation properties and immunological reactivity.
Human prolidase and prolidase deficiency: an overview on the characterization of the enzyme involved in proline recycling and on the effects of its mutations.
Human recombinant prolidase from eukaryotic and prokaryotic sources. Expression, purification, characterization and long-term stability studies.
Hyperbaric oxygen therapy in the management of severe leg ulcers from prolidase deficiency.
Identification and analysis of a novel mutation in PEPD gene in two Kashmiri siblings with prolidase enzyme deficiency.
Iminopeptiduria, skin ulcerations, and edema in a boy with prolidase deficiency.
Immune function in prolidase deficiency.
Immunochemical analyses of prolidase deficiency sera.
Immunochemical analysis of prolidase deficiency and molecular cloning of cDNA for prolidase of human liver.
Immunochemical studies of human prolidase with monoclonal and polyclonal antibodies: absence of the subunit of prolidase in erythrocytes from a patient with prolidase deficiency.
Improved prolidase activity assay allowed enzyme kinetic characterization and faster prolidase deficiency diagnosis.
In situ activation of human erythrocyte prolidase: potential for enzyme replacement therapy in prolidase deficiency.
In-vitro responses to ascorbate and manganese in fibroblasts from a patient with prolidase deficiency and iminodipeptiduria: cell growth, prolidase activity and collagen metabolism.
Inborn errors of proline metabolism.
Increased manganese content and reduced arginase activity in erythrocytes of a patient with prolidase deficiency (iminodipeptiduria).
Induction therapy with rituximab for lupus nephritis due to prolidase deficiency.
INFLAMMATORY BOWEL DISEASE-LIKE PHENOTYPE IN A YOUNG GIRL WITH PROLIDASE DEFICIENCY: A NEW SPECTRUM OF CLINICAL MANIFESTATION.
Intracellular delivery of liposome-encapsulated prolidase in cultured fibroblasts from prolidase-deficient patients.
Kinetic and structural evidences on human prolidase pathological mutants suggest strategies for enzyme functional rescue.
Lack of prolidase causes a bone phenotype both in human and in mouse.
Leg ulcers in childhood: A multicenter study in France.
Leg ulcers secondary to prolidase deficiency.
Liquid chromatography-mass spectrometry for simultaneous analyses of iminodipeptides containing an N-terminal or a C-terminal proline.
Liquid chromatography-mass spectrometry for the qualitative analyses of iminodipeptides in the urine of patients with prolidase deficiency.
Macrophage Activation Syndrome in a Patient with Prolidase Deficiency: a Rare Genetic Disorder Associated with Elevated IgE and Lupus-Like Syndrome.
Massive Splenomegaly Secondary to Prolidase Deficiency.
Measurement of iminodipeptides in the serum of patients with prolidase deficiency using liquid chromatography-mass spectrometry.
Mild, late-onset prolidase deficiency: another Italian case.
Molecular basis of prolidase (peptidase D) deficiency.
Molecular characterisation of six patients with prolidase deficiency: identification of the first small duplication in the prolidase gene and of a mutation generating symptomatic and asymptomatic outcomes within the same family.
Molecular defect in siblings with prolidase deficiency and absence or presence of clinical symptoms. A 0.8-kb deletion with breakpoints at the short, direct repeat in the PEPD gene and synthesis of abnormal messenger RNA and inactive polypeptide.
Mutation analysis of five new patients affected by prolidase deficiency: the lack of enzyme activity causes necrosis-like cell death in cultured fibroblasts.
N-benzyloxycarbonyl-L-proline: an in vitro and in vivo inhibitor of prolidase.
Nasal reconstruction in a patient with prolidase deficiency syndrome.
Normal hydroxylation of proline in collagen synthesized by skin fibroblasts from a patient with prolidase deficiency.
Normal production, nature, and extent of intracellular degradation of newly synthesized collagen in fibroblasts from a patient with prolidase deficiency.
Optimization of a capillary electrophoretic method to detect and quantify the Gly-Pro dipeptide in complex matrices from long term cultured prolidase deficiency fibroblasts.
Partial Rescue of Biochemical Parameters After Hematopoietic Stem Cell Transplantation in a Patient with Prolidase Deficiency Due to Two Novel PEPD Mutations.
Plasma Prolidase Activity and Oxidative Stress in Patients with Parkinson's Disease.
Plasma prolidase and prolinase activity in prolidase deficiency.
Polidistrectual videocapillaroscopic evaluation in a patient with prolidase deficiency.
Population screening in a Druze community: the challenge and the reward.
Presence in human cells and tissues of two prolidases and their alteration in prolidase deficiency.
Prolidase - A protein with many faces.
Prolidase and prolidase deficiency.
Prolidase deficiency among an Israeli population: prenatal diagnosis in a genetic disorder with uncertain prognosis.
Prolidase deficiency and systemic lupus erythematosus.
Prolidase deficiency and the biochemical assays used in its diagnosis.
Prolidase deficiency associated with hemoglobin O trait and microcytic anemia.
Prolidase deficiency associated with pathologic myopia.
Prolidase deficiency associated with systemic lupus erythematosus (SLE): single site experience and literature review.
Prolidase deficiency breaks tolerance to lupus-associated antigens.
Prolidase deficiency diagnosed by 1H NMR spectroscopy of urine.
Prolidase deficiency diagnosed by whole exome sequencing in a child with pulmonary capillaritis.
Prolidase Deficiency in a Mexican-American Patient Identified by Array CGH Reveals a Novel and the Largest PEPD Gene Deletion.
Prolidase deficiency in cultured human fibroblasts: biochemical pathology and iminodipeptide-enhanced growth.
Prolidase deficiency in two dermatological patients in western Sicily.
Prolidase deficiency in two siblings with chronic leg ulcerations. Clinical, biochemical, and morphologic aspects.
Prolidase deficiency in two sisters with recurrent ulcerations of the lower extremities.
Prolidase Deficiency in Very Early Onset Inflammatory Bowel Disease (VEO-IBD).
Prolidase deficiency with hyperimmunoglobulin E: a case report.
Prolidase deficiency with imidodipeptiduria. A familial case with and without clinical symptoms.
Prolidase deficiency with iminodipeptiduria: biochemical investigations and first results of attempted therapy.
Prolidase deficiency.
Prolidase deficiency. A metabolic disorder presenting with dermatologic signs.
Prolidase deficiency: a case report and literature review.
Prolidase deficiency: a multisystemic hereditary disorder.
Prolidase deficiency: a new genetic cause of combined pulmonary fibrosis and emphysema syndrome in the adult.
Prolidase deficiency: a patient without hydroxyproline-containing iminodipeptides in urine.
Prolidase deficiency: a rare aetiology of arthritis.
Prolidase deficiency: an inborn error of metabolism with major dermatological manifestations.
Prolidase deficiency: biochemical classification of alleles.
Prolidase deficiency: biochemical study of erythrocyte and skin fibroblast prolidase activity in Italian patients.
Prolidase deficiency: case reports of two Argentinian brothers.
Prolidase deficiency: characteristics of human skin fibroblast prolidase using colorimetric and fluorimetric assays.
Prolidase deficiency: dento-facial aspects in a paediatric patient.
Prolidase deficiency: detection of cases by a newborn urinary screening programme.
Prolidase deficiency: it looks like systemic lupus erythematosus but it is not.
Prolidase deficiency: its dermatological manifestations and some additional biochemical studies.
Prolidase deficiency: report of a second case with quantitation of the excessively excreted amino acids.
Prolidase deficiency: the use of topical proline for treatment of leg ulcers.
Prolidase enzyme is required for extracellular matrix integrity and impacts on postnatal cerebellar cortex development.
Prolidase function in proline metabolism and its medical and biotechnological applications.
Prolidase isoenzymes in the rat: their organ distribution, developmental change and specific inhibitors.
PROLIDASE: A Review from Discovery to its Role in Health and Disease.
Prolinase activity in prolidase-deficient fibroblasts.
Pulmonary manifestations of prolidase deficiency.
Quantitative analysis of the natural history of prolidase deficiency: description of 17 families and systematic review of published cases.
Quebec neonatal mass urinary screening programme: from micromolecules to macromolecules.
Rare diseases that mimic Systemic Lupus Erythematosus (Lupus mimickers).
Refractory leg ulcers in prolidase deficiency with antiphospholipid antibody positivity responding to aspirin-hydroxychloroquine-vitamin C combination therapy.
Screening method for prolidase deficiency.
Separation of two erythrocyte prolidase isoforms by fast protein liquid chromatography; application to prolidase deficiency.
Site-directed PEGylation as successful approach to improve the enzyme replacement in the case of prolidase.
Solitary Mastocytoma of the Eyelid in an Adult Patient With Prolidase Deficiency.
Spurious Elevation of Multiple Urine Amino Acids by Ion-Exchange Chromatography in Patients with Prolidase Deficiency.
Squamous cell carcinoma of the leg in a patient with prolidase deficiency.
Structural analysis of new compound heterozygous variants in PEPD gene identified in a patient with Prolidase Deficiency diagnosed by exome sequencing.
Structural basis for prolidase deficiency disease mechanisms.
Structural organization of the gene for human prolidase (peptidase D) and demonstration of a partial gene deletion in a patient with prolidase deficiency.
Studies on prolidase deficiency with a possible defect in collagen metabolism.
Substrate specificity and reaction mechanism of human prolidase.
Substrate specificity of manganese-activated prolidase in control and prolidase-deficient cultured skin fibroblasts.
Systemic lupus erythematosus-like disease in a 6-year-old boy with prolidase deficiency.
The "Georgian ulcers": a prolidase deficiency condition?
The effects of serum iminodipeptides and prednisolone on superoxide generation and tyrosyl phosphorylation of proteins in neutrophils from a patient with prolidase deficiency.
The hyper-IgE syndrome is not caused by a microdeletion syndrome.
The role of emerging techniques in the investigation of prolidase deficiency: From diagnosis to the development of a possible therapeutical approach.
The role of prolidase as an enzyme participating in the metabolism of collagen.
The use of liquid chromatography-mass spectrometry for the identification and quantification of urinary iminodipeptides in prolidase deficiency.
Therapeutic apheresis exchange in two patients with prolidase deficiency.
Topical proline therapy in prolidase deficiency.
Topical tacrolimus therapy in the management of lower extremity ulcers due to prolidase deficiency.
Topical treatment of skin ulcers in prolidase deficiency.
Transient beneficial effect of GH replacement therapy and topical GH application on skin ulcers in a boy with prolidase deficiency.
Ulceration in Prolidase Deficiency: Successful Treatment with Anticoagulants.
Ulcus cruris associated with prolidase deficiency.
Use of capillary zone electrophoresis for analysis of imidodipeptides in urine of prolidase-deficient patients.
[A case for diagnosis: skin ulcers and prolidase deficiency]
[A case of prolidase deficiency with leg ulcers, hypoparathyroidism and imidodipeptiduria (author's transl)]
[An inherent prolidase deficiency (author's transl)]
[Chronic leg ulcer in children with prolidase deficiency]
[Effective therapy with a glycine-proline ointment in a patient with recurrent ulcers from prolidase deficiency]
[Hereditary prolidase deficiency in 2 sisters with therapy-resistant leg ulcers]
[Hereditary prolidase deficiency. Contribution to differential therapy refractory leg ulcer diagnosis]
[Leg ulcers and prolidase deficiency]
[Leg ulcers caused by prolidase deficiency]
[Prolidase and manganese deficiency. Apropos of a case: diagnosis and treatment]
[Prolidase deficiency with various clinical conditions including hyper-IgE and multiple lung bulla formation]
[Prolidase deficiency. Apropos of a peculiar case]
[Prolidase deficiency]
Xanthomatosis, Cerebrotendinous
Population screening in a Druze community: the challenge and the reward.