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Disease on EC 3.4.11.4 - tripeptide aminopeptidase

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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Alzheimer Disease
Comparison of aminopeptidase, dipeptidyl aminopeptidase and tripeptidyl aminopeptidase activities in brain tissue from normal and Alzheimer's disease cases.
Anaphylaxis
[Determination of the dipeptidase and tripeptidase activity in anaphylactoid shock.]
Arthritis, Rheumatoid
Effects of intra-articular hydrocortisone acetate on the clinical course, aminotripeptidase activity and other changes in the synovial fluid in rheumatoid arthritis.
Atherosclerosis
[The changes in the activity of tripeptidyl peptidase II in experimental atherosclerosis and hypertension].
Autoimmune Diseases
Examination of the subcellular distribution of tripeptide aminopeptidase and evaluation of its clinical usefulness in human serum.
Breast Neoplasms
A role for nuclear translocation of tripeptidyl-peptidase II in reactive oxygen species-dependent DNA damage responses.
Burkitt Lymphoma
Tripeptidyl Peptidase II Is Required for c-MYC-Induced Centriole Overduplication and a Novel Therapeutic Target in c-MYC-Associated Neoplasms.
Carcinogenesis
Linking TPPII to the protein interaction and signalling networks.
The protein-interaction network with functional roles in tumorigenesis, neurodegeneration, and aging.
Carcinoma
Tripeptidyl peptidase II in human oral squamous cell carcinoma.
Carcinoma, Hepatocellular
Clinical usefulness of serum tripeptide aminopeptidase activity in diagnosing liver diseases.
Colonic Neoplasms
Changes in spatio-temporal localization of tripeptidyl peptidase II (TPPII) in murine colon adenocarcinoma cells during aggresome formation: a microscopy study based on a novel fluorescent proteasome inhibitor.
Coxsackievirus Infections
Tripeptidyl peptidase II serves as an alternative to impaired proteasome to maintain viral growth in the host cells.
Hepatitis B
Adenovirus Vector Harboring the HBcAg and Tripeptidyl Peptidase II Genes Induces Potent Cellular Immune Responses In Vivo.
Hypercholesterolemia
[The changes in the activity of tripeptidyl peptidase II in experimental atherosclerosis and hypertension].
Hypertension
[The changes in the activity of tripeptidyl peptidase II in experimental atherosclerosis and hypertension].
Leukemia
Examination of the subcellular distribution of tripeptide aminopeptidase and evaluation of its clinical usefulness in human serum.
Liver Diseases
Clinical usefulness of serum tripeptide aminopeptidase activity in diagnosing liver diseases.
Lung Neoplasms
Linking TPPII to the protein interaction and signalling networks.
Lymphocytic Choriomeningitis
Analysis of the Role of Tripeptidyl Peptidase II in MHC Class I Antigen Presentation In Vivo.
No essential role for tripeptidyl peptidase II for the processing of LCMV-derived T cell epitopes.
Lymphoma
A role for nuclear translocation of tripeptidyl-peptidase II in reactive oxygen species-dependent DNA damage responses.
Activation of cellular death programs associated with immunosenescence-like phenotype in TPPII knockout mice.
Tripeptidyl-peptidase II controls DNA damage responses and in vivo gamma-irradiation resistance of tumors.
Lysosomal Storage Diseases
Glycosaminoglycans modulate activation, activity, and stability of tripeptidyl-peptidase I in vitro and in vivo.
Melanoma
A role for nuclear translocation of tripeptidyl-peptidase II in reactive oxygen species-dependent DNA damage responses.
MAP kinase-signaling controls nuclear translocation of tripeptidyl-peptidase II in response to DNA damage and oxidative stress.
Myocardial Infarction
[Tripeptidase activity in the blood serum in the course of myocardial infarct.]
Neoplasms
Distribution of tripeptidyl peptidase I in human tissues under normal and pathological conditions.
Effect of cancer cachexia on the activity of tripeptidyl-peptidase II in skeletal muscle.
ISCOMATRIX adjuvant induces efficient cross-presentation of tumor antigen by dendritic cells via rapid cytosolic antigen delivery and processing via tripeptidyl peptidase II.
MAP kinase-signaling controls nuclear translocation of tripeptidyl-peptidase II in response to DNA damage and oxidative stress.
TPPII, MYBBP1A and CDK2 form a protein-protein interaction network.
Tripeptidyl Peptidase II Is Required for c-MYC-Induced Centriole Overduplication and a Novel Therapeutic Target in c-MYC-Associated Neoplasms.
Tripeptidyl peptidase II plays a role in the radiation response of selected primary cell types but not based on nuclear translocation and p53 stabilization.
Tripeptidyl-peptidase II controls DNA damage responses and in vivo gamma-irradiation resistance of tumors.
Tumors acquire inhibitor of apoptosis protein (IAP)-mediated apoptosis resistance through altered specificity of cytosolic proteolysis.
Viability and DNA damage responses of TPPII-deficient Myc- and Ras-transformed fibroblasts.
[Aldolase, dipeptidase, tripeptidase, tributyrinase, phosphatase, amylase, proteins and protein polysaccharides in the blood serum and ascites fluid in the mouse ascites tumor.]
Neurodegenerative Diseases
Prosegment of tripeptidyl peptidase I is a potent, slow-binding inhibitor of its cognate enzyme.
[Tripeptidyl-peptidase I--distribution, biogenesis, and mechanisms of activation]
Neuronal Ceroid-Lipofuscinoses
Biosynthesis, glycosylation, and enzymatic processing in vivo of human tripeptidyl-peptidase I.
Glycosaminoglycans modulate activation, activity, and stability of tripeptidyl-peptidase I in vitro and in vivo.
N-glycosylation is crucial for folding, trafficking, and stability of human tripeptidyl-peptidase I.
Prosegment of tripeptidyl peptidase I is a potent, slow-binding inhibitor of its cognate enzyme.
Ser475, Glu272, Asp276, Asp327, and Asp360 are involved in catalytic activity of human tripeptidyl-peptidase I.
[Tripeptidyl-peptidase I--distribution, biogenesis, and mechanisms of activation]
Renal Insufficiency
[Tripeptidase activity of plasma during renal insufficiency; contribution to the study of protein catabolism.]
Renal Insufficiency, Chronic
[Serum tripeptidase activity in acute and chronic renal insufficiency (author's transl)]
Rheumatic Fever
[Observation of serum aminotripeptidase activity in rheumatic fever]
Sarcoma
A role for nuclear translocation of tripeptidyl-peptidase II in reactive oxygen species-dependent DNA damage responses.
Sepsis
Tripeptidyl-peptidase II expression and activity are increased in skeletal muscle during sepsis.
Squamous Cell Carcinoma of Head and Neck
Tripeptidyl peptidase II in human oral squamous cell carcinoma.
tripeptide aminopeptidase deficiency
Activation of cellular death programs associated with immunosenescence-like phenotype in TPPII knockout mice.
Uveitis
[On the peptidase activity of the aqueous humor in the course of experimental anaphylactic uveitis (aminodipeptidase and aminotripeptidase activities).]
Vaccinia
Analysis of the Role of Tripeptidyl Peptidase II in MHC Class I Antigen Presentation In Vivo.
Virus Diseases
Tripeptidyl peptidase II serves as an alternative to impaired proteasome to maintain viral growth in the host cells.