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Disease on EC 3.4.11.3 - cystinyl aminopeptidase

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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Abortion, Habitual
The Effectiveness of Adrenocorticotropin Repeated Doses in High Risk Pregnancies.
Abortion, Spontaneous
Changes of maternal ACTH and oxytocinase plasma concentrations during the first trimester of spontaneous abortion.
Comparison of periovulatory and early pregnancy blood levels of oxytocinase (CAP1) and isooxytocinase (CAP2).
Abortion, Threatened
[INCREASE IN MATERNAL SERUM OXYTOCINASE LEVEL CAUSED BY ADMINISTRATION OF A GESTAGEN IN THREATENED ABORTION.]
[Serum oxytocin and oxytocinase activities in women during pregnancy]
[Thermostable alkaline phosphatase and oxytocinase activity in late-term threatened abortion]
Abruptio Placentae
Acute diabetes insipidus mediated by vasopressinase after placental abruption.
Acquired Immunodeficiency Syndrome
A mechanism of restricted human immunodeficiency virus type 1 expression in human glial cells.
AIDS in Thailand: a medical student's perspective.
Anti-V3 antibody reactivity correlates with clinical stage of HIV-1 infection and with serum neutralizing activity.
Antibodies to human T-lymphotropic virus type III (HTLV-III) in saliva of acquired immunodeficiency syndrome (AIDS) patients and in persons at risk for AIDS.
Antibody to human immunodeficiency virus type 1 (HIV-1) gp160 in mucosal specimens of asymptomatic HIV-1-infected volunteers parenterally immunized with an experimental recombinant HIV-1 IIIB gp160 vaccine. The National Institute of Allergy and Infectious Diseases-sponsored AIDS Vaccine Evaluation Group.
Augmentation of human immunodeficiency virus type 1 neutralizing antibody by priming with gp160 recombinant vaccinia and boosting with rgp160 in vaccinia-naive adults. The NIAID AIDS Vaccine Clinical Trials Network.
B-cell activation and differentiation by HIV-1 antigens among volunteers vaccinated with VaxSyn HIV-1.
Characteristics of a population volunteering for human immunodeficiency virus immunization. NIAID AIDS Clinical Trials Network.
Characterization of serum antibody responses to recombinant HIV-1 gp160 vaccine by enzyme immunoassay. NIAID AIDS Vaccine Clinical Trials Network.
Comparative evaluation of HIV infected foreign students and Indian with AIDS in Chandigarh, India.
Detection of binding antibodies to native and recombinant human immunodeficiency virus type 1 envelope glycoproteins following recombinant gp160 immunization measured by flow cytometry and enzyme immunoassays. The AIDS Vaccine Clinical Trials Network.
Determinants of antibody response after recombinant gp160 boosting in vaccinia-naive volunteers primed with gp160-recombinant vaccinia virus. The National Institute of Allergy and Infectious Diseases AIDS Vaccine Clinical Trials Network.
DNA-protein complexes. Natural targets for DNA-hydrolyzing antibodies.
Effect of a recombinant HIV gp160 vaccine on monokine production.
Efficacy of a multigenic protein vaccine containing multimeric HIV gp160 against heterologous SHIV clade C challenges.
HIV experimental vaccines based on the iscom technology using envelope and GAG gene products.
HIV-1 envelope accessible surface and polarity: clade, blood, and brain.
HIV-1 recombinant gp160 vaccine given in accelerated dose schedules. NIAID AIDS Vaccine Clinical Trials Network.
HIV-1 recombinant gp160 vaccine induced antibodies in serum and saliva. The NIAID AIDS Vaccine Clinical Trials Network.
Identifiable biomarker and treatment development using HIV-1 long term non-progressor sera.
Immunization with subunit human immunodeficiency virus vaccine generates stronger T helper cell immunity than natural infection.
Intracellular diversion of glycoprotein GP160 of human immunodeficiency virus to lysosomes as a strategy of AIDS gene therapy.
Long-term protection of chimpanzees against high-dose HIV-1 challenge induced by immunization.
Lymphocyte proliferative responses following immunization with human immunodeficiency virus recombinant GP160. The NIAID AIDS Vaccine Clinical Trials Network.
Lymphoproliferative responses to mitogens and HIV-1 envelope glycoprotein among volunteers vaccinated with recombinant gp160.
Modifications of the human immunodeficiency virus envelope glycoprotein enhance immunogenicity for genetic immunization.
Modulation of immunologic responses to HIV-1MN recombinant gp160 vaccine by dose and schedule of administration. National Institute of Allergy and Infectious Diseases AIDS Vaccine Evaluation Group.
Molecular cloning and analysis of functional envelope genes from human immunodeficiency virus type 1 sequence subtypes A through G. The WHO and NIAID Networks for HIV Isolation and Characterization.
Recombinant gp160 as a therapeutic vaccine for HIV-infection: results of a large randomized, controlled trial. European Multinational IMMUNO AIDS Vaccine Study Group.
Recombinant gp160 vaccination schedule and MHC HLA type as factors influencing cellular responses to HIV-1 envelope glycoprotein. NIAID AIDS Vaccine Clinical Trials Network.
Removal of gp160 induced bio-hazards for a safe AIDS vaccine candidate.
Retroviruses associated with leukemia and ablative syndromes in animals and in human beings.
Safety and immunogenicity of a fully glycosylated recombinant gp160 human immunodeficiency virus type 1 vaccine in subjects at low risk of infection. National Institute of Allergy and Infectious Diseases AIDS Vaccine Evaluation Group Network.
Sequential changes in antibody levels to the env and gag antigens in human immunodeficiency virus infected subjects.
Serum antibodies to HIV-1 in recombinant vaccinia virus recipients boosted with purified recombinant gp160. NIAID AIDS Vaccine Clinical Trials Network.
Serum IgA subclasses and molecular forms in HIV infection: selective increases in monomer and apparent restriction of the antibody response to IgA1 antibodies mainly directed at env glycoproteins.
The safety and immunogenicity of a human immunodeficiency virus type 1 (HIV-1) recombinant gp160 candidate vaccine in humans. NIAID AIDS Vaccine Clinical Trials Network.
Vaccination of vaccinia-naive adults with human immunodeficiency virus type 1 gp160 recombinant vaccinia virus in a blinded, controlled, randomized clinical trial. The AIDS Vaccine Clinical Trials Network.
Adenocarcinoma
A novel role for placental leucine aminopeptidase (P-LAP) as a determinant of chemoresistance in endometrial carcinoma cells.
P-LAP/IRAP-induced cell proliferation and glucose uptake in endometrial carcinoma cells via insulin receptor signaling.
Placental leucine aminopeptidase (P-LAP) and glucose transporter 4 (GLUT4) expression in benign, borderline, and malignant ovarian epithelia.
Possible role of placental leucine aminopeptidase in the antiproliferative effect of oxytocin in human endometrial adenocarcinoma.
VP-16, cyclophosphamide, adriamycin and cis-platinum (V:CAP-I) in patients with metastatic adenocarcinoma of the lung.
[Cystine aminopeptidase activity is not a marker of ovarian adenocarcinoma]
AIDS Dementia Complex
Analysis of human immunodeficiency virus type 1 gp160 sequences from a patient with HIV dementia: evidence for monocyte trafficking into brain.
AIDS-Related Complex
Antibodies to human T-lymphotropic virus type III (HTLV-III) in saliva of acquired immunodeficiency syndrome (AIDS) patients and in persons at risk for AIDS.
Serum IgA subclasses and molecular forms in HIV infection: selective increases in monomer and apparent restriction of the antibody response to IgA1 antibodies mainly directed at env glycoproteins.
Alzheimer Disease
Changes of renin-angiotensin system-related aminopeptidases in early stage Alzheimer's disease.
IRAP Inhibitors: M1-Aminopeptidase Family Inspiration.
Putative Involvement of Endocrine Disruptors in the Alzheimer's disease Via the Insulin-Regulated Aminopeptidase / GLUT4 Pathway.
Regulation of insulin-regulated membrane aminopeptidase activity by its C-terminal domain.
The angiotensin AT4 receptor subtype as a target for the treatment of memory dysfunction associated with Alzheimer's disease.
Anthrax
The kindest cuts of all: crystal structures of Kex2 and furin reveal secrets of precursor processing.
Aortic Valve Disease
Differential Gene Expression Profile of Renin-Angiotensin System in the Left Atrium in Mitral Regurgitation Patients.
Astrocytoma
Differential Effects of Doxazosin on Renin-Angiotensin-System-Regulating Aminopeptidase Activities in Neuroblastoma and Glioma Tumoral Cells.
Bacterial Infections
Novel single-round PCR and cloning of full-length envelope genes of HIV-1 may yield new insight into biomolecular antibacterial drug development.
Breast Neoplasms
A PCR-RFLP method for detection of the LNPEP encoding human insulin-regulated aminopeptidase (IRAP) rs4869317 polymorphism.
Insulin-Regulated Aminopeptidase in Women with Breast Cancer: A Role beyond the Regulation of Oxytocin and Vasopressin.
Insulin-regulated aminopeptidase/placental leucil Aminopeptidase (IRAP/P-lAP) and angiotensin IV-forming activities are modified in serum of rats with breast cancer induced by N-methyl-nitrosourea.
Serum oxytocinase activity is related to tumor growth parameters in N-methyl nitrosourea induced rat breast cancer.
Carcinogenesis
Insulin-regulated aminopeptidase/placental leucil Aminopeptidase (IRAP/P-lAP) and angiotensin IV-forming activities are modified in serum of rats with breast cancer induced by N-methyl-nitrosourea.
Serum oxytocinase activity is related to tumor growth parameters in N-methyl nitrosourea induced rat breast cancer.
Carcinoma
Aminopeptidase A expression and enzymatic activity in primary human renal cancers.
Cystinyl aminopeptidase activity is decreased in renal cell carcinomas.
Essential role of placental leucine aminopeptidase in gynecologic malignancy.
Expression of placental leucine aminopeptidase is associated with a poor outcome in endometrial endometrioid adenocarcinoma.
Expression of the kidney-associated differentiation glycoprotein gp160 and resistance to the antitumor effects of interferon alpha in renal cell carcinomas.
Molecular cloning of the human kidney differentiation antigen gp160: human aminopeptidase A.
Placental leucine aminopeptidase (P-LAP) and glucose transporter 4 (GLUT4) expression in benign, borderline, and malignant ovarian epithelia.
Possible role of placental leucine aminopeptidase in the antiproliferative effect of oxytocin in human endometrial adenocarcinoma.
Primary or delayed debulking surgery and chemotherapy consisting of cisplatin, doxorubicin, and cyclophosphamide in stage III-IV epithelial ovarian carcinoma.
[Clinical evaluation of serum placental leucine aminopeptidase (P-LAP) activity in renal cell carcinoma]
[Expression of GP160 mRNA in renal cell carcinoma: an attempt to predict the sensitivity of IFN-alpha therapy]
[Markers of carcinoma of the ovary: serum cystine aminopeptidase and leucine aminopeptidase, reliable diagnostic parameters?]
Carcinoma, Endometrioid
Expression of placental leucine aminopeptidase is associated with a poor outcome in endometrial endometrioid adenocarcinoma.
Carcinoma, Hepatocellular
CircLNPEP promotes the progression of ovarian cancer through regulating miR-876-3p/ WNT5A axis.
Carcinoma, Renal Cell
Cystinyl aminopeptidase activity is decreased in renal cell carcinomas.
Expression of the kidney-associated differentiation glycoprotein gp160 and resistance to the antitumor effects of interferon alpha in renal cell carcinomas.
Molecular cloning of the human kidney differentiation antigen gp160: human aminopeptidase A.
[Clinical evaluation of serum placental leucine aminopeptidase (P-LAP) activity in renal cell carcinoma]
[Expression of GP160 mRNA in renal cell carcinoma: an attempt to predict the sensitivity of IFN-alpha therapy]
Cardiovascular Diseases
Identification of a Missense Variant in LNPEP that Confers Psoriasis Risk.
Chagas Disease
High-Level Expression in Escherichia coli, Purification and Kinetic Characterization of LAPTc, a Trypanosoma cruzi M17-Aminopeptidase.
Cholera
Proteosomes, emulsomes, and cholera toxin B improve nasal immunogenicity of human immunodeficiency virus gp160 in mice: induction of serum, intestinal, vaginal, and lung IgA and IgG.
Chorioamnionitis
Interleukin-1beta stimulates placental leucine aminopeptidase/oxytocinase expression in BeWo choriocarcinoma cells.
Choriocarcinoma
Ap-2 and Ikaros regulate transcription of human placental leucine aminopeptidase/oxytocinase gene.
Expression of placental leucine aminopeptidase and adipocyte-derived leucine aminopeptidase in human normal and malignant invasive trophoblastic cells.
Ikaros is expressed in human extravillous trophoblasts and involved in their migration and invasion.
Insulin stimulates placental leucine aminopeptidase/oxytocinase/insulin-regulated membrane aminopeptidase expression in BeWo choriocarcinoma cells.
Interleukin-1beta stimulates placental leucine aminopeptidase/oxytocinase expression in BeWo choriocarcinoma cells.
Placental leucine aminopeptidase/oxytocinase gene regulation by activator protein-2 in BeWo cell model of human trophoblast differentiation.
Regulatory role of membrane-bound peptidases in the progression of gynecologic malignancies.
Transcriptional regulation of human placental leucine aminopeptidase/oxytocinase gene.
Coinfection
Expression and processing of the human immunodeficiency virus type 1 envelope glycoprotein.
Production and characterization of simian--human immunodeficiency virus-like particles.
Communicable Diseases
Determinants of antibody response after recombinant gp160 boosting in vaccinia-naive volunteers primed with gp160-recombinant vaccinia virus. The National Institute of Allergy and Infectious Diseases AIDS Vaccine Clinical Trials Network.
HIV-1 envelope accessible surface and polarity: clade, blood, and brain.
Modulation of immunologic responses to HIV-1MN recombinant gp160 vaccine by dose and schedule of administration. National Institute of Allergy and Infectious Diseases AIDS Vaccine Evaluation Group.
Safety and immunogenicity of a fully glycosylated recombinant gp160 human immunodeficiency virus type 1 vaccine in subjects at low risk of infection. National Institute of Allergy and Infectious Diseases AIDS Vaccine Evaluation Group Network.
Cystadenoma
Placental leucine aminopeptidase (P-LAP) and glucose transporter 4 (GLUT4) expression in benign, borderline, and malignant ovarian epithelia.
Cystadenoma, Mucinous
Placental leucine aminopeptidase (P-LAP) and glucose transporter 4 (GLUT4) expression in benign, borderline, and malignant ovarian epithelia.
cystinyl aminopeptidase deficiency
Insulin-regulated aminopeptidase deficiency impairs cardiovascular adaptations and placental development during pregnancy.
Insulin-Regulated Aminopeptidase Deficiency Provides Protection against Ischemic Stroke in Mice.
Dementia
HIV-1 gp120 proteins and gp160 peptides are toxic to brain endothelial cells and neurons: possible pathway for HIV entry into the brain and HIV-associated dementia.
Dengue
Development of dengue virus replicons expressing HIV-1 gp120 and other heterologous genes: a potential future tool for dual vaccination against dengue virus and HIV.
Diabetes Insipidus
Acute diabetes insipidus mediated by vasopressinase after placental abruption.
Clinical Practice Guideline for Hypotalamic-Pituitary Disturbances in Pregnancy and the Postpartum Period.
Diabetes insipidus in pregnancy associated with abnormally high circulating vasopressinase activity.
Diabetes insipidus in pregnancy.
Diabetes insipidus in pregnancy: etiology, evaluation, and management.
Diabetes insipidus in pregnancy: how to advice the patient?
Diabetes insipidus in the third trimester of pregnancy.
Diagnosis and management of diabetes insipidus for the internist: an update.
Gestational diabetes insipidus: a review of an underdiagnosed condition.
Loss of biological activity of arginine vasopressin during its degradation by vasopressinase from pregnancy serum.
Other Pituitary Conditions and Pregnancy.
Pathophysiology of transient cranial diabetes insipidus during pregnancy.
Pituitary diseases in pregnancy.
Pituitary disorders during pregnancy.
Recurrent pregnancy-induced diabetes insipidus in a woman with hemochromatosis.
Severe hydramnios and preterm delivery in association with transient maternal diabetes insipidus.
Systemic arterial vasodilation, vasopressin, and vasopressinase in pregnancy.
The clinical course and pathophysiological investigation of adolescent gestational diabetes insipidus: a case report.
The management of diabetes insipidus in adults.
Transient diabetes insipidus in a post-partum woman with pre-eclampsia associated with residual placental vasopressinase activity.
Transient postpartum diabetes insipidus associated with HELLP syndrome.
Usefulness of anti-rabphilin-3A antibodies for diagnosing central diabetes insipidus in the third trimester of pregnancy.
Vasopressin inactivation: Role of insulin-regulated aminopeptidase.
Vasopressinase and diabetes insipidus of pregnancy.
Vasopressinase-altered vasopressin elevates arterial pressure in anesthetized rats.
[Diabetes insipidus and postpartum anterior hypophyseal insufficiency]
[Diabetes insipidus with a hypothalamo-hypophyseal morphologic anomaly during a pregnancy]
Diabetes Insipidus, Nephrogenic
Diabetes insipidus in pregnancy: how to advice the patient?
Diagnosis and management of diabetes insipidus for the internist: an update.
The management of diabetes insipidus in adults.
Diabetes Insipidus, Neurogenic
Diagnosis and management of diabetes insipidus for the internist: an update.
The management of diabetes insipidus in adults.
Diabetes Mellitus
Adipocytes exhibit abnormal subcellular distribution and translocation of vesicles containing glucose transporter 4 and insulin-regulated aminopeptidase in type 2 diabetes mellitus: implications regarding defects in vesicle trafficking.
Circulating IRAPe, Irisin, and IL-34 in Relation to Insulin Resistance in Patients With Type 2 Diabetes.
Diabetes Mellitus, Type 2
Adipocytes exhibit abnormal subcellular distribution and translocation of vesicles containing glucose transporter 4 and insulin-regulated aminopeptidase in type 2 diabetes mellitus: implications regarding defects in vesicle trafficking.
Circulating IRAPe, Irisin, and IL-34 in Relation to Insulin Resistance in Patients With Type 2 Diabetes.
Diabetes, Gestational
Associations between serum placental leucine aminopeptidase and pregnancy outcomes.
Diabetes insipidus in pregnancy: how to advice the patient?
Diagnosis and management of diabetes insipidus for the internist: an update.
Loss of biological activity of arginine vasopressin during its degradation by vasopressinase from pregnancy serum.
The clinical course and pathophysiological investigation of adolescent gestational diabetes insipidus: a case report.
Vasopressin inactivation: Role of insulin-regulated aminopeptidase.
Diphtheria
Human immunodeficiency virus-1 glycoproteins gp120 and gp160 specifically inhibit the CD3/T cell-antigen receptor phosphoinositide transduction pathway.
Eclampsia
Genetic association of ERAP1 and ERAP2 with eclampsia and preeclampsia in northeastern Brazilian women.
Encephalitis
HIV-1 envelope accessible surface and polarity: clade, blood, and brain.
Endometrial Neoplasms
A novel role for placental leucine aminopeptidase (P-LAP) as a determinant of chemoresistance in endometrial carcinoma cells.
Expression of placental leucine aminopeptidase is associated with a poor outcome in endometrial endometrioid adenocarcinoma.
P-LAP/IRAP-induced cell proliferation and glucose uptake in endometrial carcinoma cells via insulin receptor signaling.
Placental leucine aminopeptidase (P-LAP) expression is associated with chemosensitivity in human endometrial carcinoma.
Regulatory role of membrane-bound peptidases in the progression of gynecologic malignancies.
Serum cystine aminopeptidase and leucine aminopeptidase activity in women with benign and malignant uterine and ovarian tumors.
Essential Hypertension
Circulating Aminopeptidase Activities in Men and Women with Essential Hypertension.
Fatty Liver
Gestational diabetes insipidus and intrauterine fetal death of monochorionic twins.
Recurrent pregnancy-induced diabetes insipidus in a woman with hemochromatosis.
Transient diabetes insipidus in pregnancy.
Fetal Death
Associations between serum placental leucine aminopeptidase and pregnancy outcomes.
[DETERMINATION OF SERUM OXYTOCINASE IN PLACENTAL INSUFFICIENCY AND FETAL DEATH "IN UTERO".]
Fetal Growth Retardation
An 18-month follow-up study of growth-retarded neonates. Relation to biochemical tests of placental function in late pregnancy and neurobehavioural condition in the newborn period.
Cystyl aminopeptidase in maternal serum for the antenatal recognition of fetal growth retardation.
Diagnosis of intrauterine fetal growth retardation by serial serum oxytocinase, urinary oestrogen and serum heat stable alkaline phosphatase (HSAP) estimations in uncomplicated and hypertensive pregnancies.
Neurology and behaviour of growth-retarded neonates. Relation to biochemical placental function tests in late pregnancy.
Oxytocinase and human placental lactogen for the prediction of intrauterine growth retardation.
The use of human placental lactogen, oxytocinase and estriol in twin pregnancies with intrauterine growth retardation.
The value of serum cystine aminopeptidase (CAP), human chorionic somato-mammotrophin (HCS), and urinary oestrogen assays for detecting intrauterine growth retardation.
[Placental oxytocinase and alkaline phosphatase activities and the SP1-glycoprotein level in pregnancy complicated by intrauterine fetal growth retardation]
[Serial determinations of serum oxytocinase and ultrasonic biparietal cephalometry in normal and high-risk pregnancies]
[Serum HPL, total estrogen excretion and serum oxytocinase in intrauterine retardation. Results of 3 evaluation procedures]
Fibromyalgia
Altered Serum Oxytocinase and Enkephalin-Degrading Aminopeptidase Activities in Patients With Fibromyalgia.
Associations Among Nitric Oxide and Enkephalinases With Fibromyalgia Symptoms.
Glomerulosclerosis, Focal Segmental
HIV-1 gp160 protein-macrophage interactions modulate mesangial cell proliferation and matrix synthesis.
Goiter
Blood levels of cystine aminopeptidase (oxytocinase) in patients with toxic and simple goiter.
Hearing Loss
A normative study of auditory perception in Mandarin-speaking children with categories of auditory Performance-II.
Inter-rater Reliability and Validity of the Arabic Version of Categories of Auditory Performance-II (CAP-II) Among Children With Cochlear Implant.
HELLP Syndrome
Genetic association of ERAP1 and ERAP2 with eclampsia and preeclampsia in northeastern Brazilian women.
Gestational diabetes insipidus and intrauterine fetal death of monochorionic twins.
Recurrent pregnancy-induced diabetes insipidus in a woman with hemochromatosis.
Transient diabetes insipidus in pregnancy.
Transient postpartum diabetes insipidus associated with HELLP syndrome.
Transient postpartum diabetes insipidus in twin pregnancy associated with HELLP syndrome.
Hepatitis
Characterization of a vaccinia-derived recombinant HIV-1 gp160 candidate vaccine and its immunogenicity in chimpanzees.
Transient diabetes insipidus in pregnancy.
[Leucine aminopeptidase and cystinyl aminopeptidase activity of serum during the course of viral hepatitis, with reference to the effect of cortico therapy]
Hepatitis B
B-cell activation and differentiation by HIV-1 antigens among volunteers vaccinated with VaxSyn HIV-1.
Enhancement of human immunodeficiency virus (HIV)-specific CD4+ and CD8+ cytotoxic T-lymphocyte activities in HIV-infected asymptomatic patients given recombinant gp160 vaccine.
Priming of class I-restricted cytotoxic T lymphocytes by vaccination with recombinant protein antigens.
Sequential cleavage by metallopeptidases and proteasomes is involved in processing HIV-1 ENV epitope for endogenous MHC class I antigen presentation.
Herpes Simplex
Analysis of Select Herpes Simplex Virus 1 (HSV-1) Proteins for Restriction of Human Immunodeficiency Virus Type 1 (HIV-1): HSV-1 gM Protein Potently Restricts HIV-1 by Preventing Intracellular Transport and Processing of Env gp160.
HIV Infections
A phase I evaluation of the safety and immunogenicity of vaccination with recombinant gp160 in patients with early human immunodeficiency virus infection. Military Medical Consortium for Applied Retroviral Research.
Antibody response in primary human immunodeficiency virus infection.
Concomitant human immunodeficiency virus infection and syphilitic meningitis.
Decreased cervicovaginal production of both IgA1 and IgA2 subclasses in women with AIDS.
HIV-1 envelope-elicited neutralizing antibody titres correlate with protection and virus load in chimpanzees.
HIV-1 gp160 induces transforming growth factor-beta production in human PBMC.
Host-Epstein-Barr virus relationship affected by immunostimulation in HIV-infected patients representing distinct progressor profile groups.
Human immunodeficiency virus type 1 glycoprotein precursor retains a CD4-p56lck complex in the endoplasmic reticulum.
Human immunodeficiency virus type 1 Vpu protein induces rapid degradation of CD4.
Immune responses to a recombinant human immunodeficiency virus type 1 (HIV-1) gpl60 vaccine among adults with advanced HIV infection. Massachusetts gp160 Working Group.
Unsupervised PrEP in routine practice: a new challenge?
[A case of primary HIV infection presenting as meningoencephalitis]
[A case of primary HIV infection presenting as mononeuritis multiplex]
HIV Seropositivity
Detection of antibodies to human immunodeficiency virus (HIV) that recognize conformational epitopes of glycoproteins 160 and 41 often allows for early diagnosis of HIV infection.
Hydatidiform Mole
Differential distribution of placental leucine aminopeptidase/oxytocinase and aminopeptidase A in human trophoblasts of normal placenta and complete hydatidiform mole.
Hyperalgesia
A possible correlation between oxytocin-induced and angiotensin IV-induced anti-hyperalgesia at the spinal level in rats.
Hyperinsulinism
Putative Involvement of Endocrine Disruptors in the Alzheimer's disease Via the Insulin-Regulated Aminopeptidase / GLUT4 Pathway.
Hypernatremia
Gestational Diabetes Insipidus Associated with HELLP Syndrome: A Case Report.
Hypersensitivity
Antibody to human immunodeficiency virus type 1 (HIV-1) gp160 in mucosal specimens of asymptomatic HIV-1-infected volunteers parenterally immunized with an experimental recombinant HIV-1 IIIB gp160 vaccine. The National Institute of Allergy and Infectious Diseases-sponsored AIDS Vaccine Evaluation Group.
Determinants of antibody response after recombinant gp160 boosting in vaccinia-naive volunteers primed with gp160-recombinant vaccinia virus. The National Institute of Allergy and Infectious Diseases AIDS Vaccine Clinical Trials Network.
HIV-1 envelope accessible surface and polarity: clade, blood, and brain.
Modulation of immunologic responses to HIV-1MN recombinant gp160 vaccine by dose and schedule of administration. National Institute of Allergy and Infectious Diseases AIDS Vaccine Evaluation Group.
Oxytocin hypersensitivity in pregnant P-LAP deficient mice.
Safety and immunogenicity of a fully glycosylated recombinant gp160 human immunodeficiency virus type 1 vaccine in subjects at low risk of infection. National Institute of Allergy and Infectious Diseases AIDS Vaccine Evaluation Group Network.
Hypersensitivity, Delayed
A group specific anamnestic immune reaction against HIV-1 induced by a candidate vaccine against AIDS.
Hypertension
Effect of valsartan on angiotensin II- and vasopressin-degrading activities in the kidney of normotensive and hypertensive rats.
Genetic association of ERAP1 and ERAP2 with eclampsia and preeclampsia in northeastern Brazilian women.
Oxytocinase and human placental lactogen for the prediction of intrauterine growth retardation.
Plasma angiotensin I concentration and serum placental leucine aminopeptidase (P-LAP) activities in puerperal hypertension.
Hypertension, Pregnancy-Induced
Change in plasma cystyl aminopeptidase (oxytocinase) between 30-34 weeks' gestation as a predictor of pregnancy-induced hypertension.
Serum Vasopressinase and Platelet Responses to Arginine Vasopressin in Normal Pregnancy, Pregnancy-induced Hypertension and Pre-eclampsia.
Hyperthyroidism
Cystinyl and pyroglutamyl-beta-naphthylamide hydrolyzing activities are modified coordinately between hypothalamus, liver and plasma depending on the thyroid status of adult male rats.
Thyroid Disorders Change the Pattern of Response of Angiotensinase Activities in the Hypothalamus-Pituitary-Adrenal Axis of Male Rats.
Hypothalamic Diseases
Volume homeostasis and osmoregulation in human pregnancy.
Hypothyroidism
Cystinyl and pyroglutamyl-beta-naphthylamide hydrolyzing activities are modified coordinately between hypothalamus, liver and plasma depending on the thyroid status of adult male rats.
Immune System Diseases
IRAP Inhibitors: M1-Aminopeptidase Family Inspiration.
Infections
A mechanism of restricted human immunodeficiency virus type 1 expression in human glial cells.
A prime-boost approach to HIV preventive vaccine using a recombinant canarypox virus expressing glycoprotein 160 (MN) followed by a recombinant glycoprotein 160 (MN/LAI). The AGIS Group, and l'Agence Nationale de Recherche sur le SIDA.
Acute HIV-1 seroconversion with an unusual plasma biomarker profile.
An evolutionarily conserved splice generates a secreted env-Bet fusion protein during human foamy virus infection.
Analysis of endoproteolytic cleavage and intracellular transport of human immunodeficiency virus type 1 envelope glycoproteins using mutant CD4 molecules bearing the transmembrane endoplasmic reticulum retention signal.
Antibodies to the putative SIV infection-enhancing domain diminish beneficial effects of an SIV gp160 vaccine in rhesus macaques.
Antibody responses in early human immunodeficiency virus type 1 infection in hemophiliacs.
Antigenic specificity of antibody-dependent cell-mediated cytotoxicity directed against human immunodeficiency virus in antibody-positive sera.
Autologous neutralizing humoral immunity and evolution of the viral envelope in the course of subtype B human immunodeficiency virus type 1 infection.
Bioengineered intravaginal isolate of Lactobacillus plantarum expresses algal lectin scytovirin demonstrating anti-HIV-1 activity.
Breakthrough infections during phase 1 and 2 prime-boost HIV-1 vaccine trials with canarypox vectors (ALVAC) and booster dose of recombinant gp120 or gp160.
Characteristics of IgA antibodies against HIV-1 in sera and saliva from HIV-seropositive individuals in different clinical stages.
Characterization of a soluble, oligomeric HIV-1 gp160 protein as a potential immunogen.
Characterization of siamycin I, a human immunodeficiency virus fusion inhibitor.
Characterization of the functional properties of env genes from long-term survivors of human immunodeficiency virus type 1 infection.
Comparison of cervicovaginal humoral immunity in clinically asymptomatic (CDC A1 and A2 category) patients with HIV-1 and HIV-2 infection.
Complement-activating antibodies in sera from infected individuals and vaccinated volunteers that target human immunodeficiency virus type 1 to complement receptor type 1 (CR1, CD35).
Cross-clade envelope glycoprotein 160-specific CD8+ cytotoxic T lymphocyte responses in early HIV type 1 clade B infection.
Cross-neutralizing antibodies in rabbits immunized with HIV-1 gp160 purified from simian cells infected with a recombinant vaccinia virus.
Cutting edge: a single MHC class Ia is sufficient for CD8 memory T cell differentiation.
DNA prime/protein boost vaccine strategy in neonatal macaques against simian human immunodeficiency virus.
Effect of alpha-1 antitrypsin Portland variant (alpha 1-PDX) on HIV-1 replication.
Erratum to "Relevance of the antibody response against human immunodeficiency virus type 1 envelope to vaccine design".
Evidence for the role of CR1 (CD35), in addition to CR2 (CD21), in facilitating infection of human T cells with opsonized HIV.
Extensive C-terminal deletion in human immunodeficiency virus type 1 Env glycoprotein arising after long-term culture of chronically infected cells.
Failure of a human immunodeficiency virus type 1 (HIV-1) subtype B-derived vaccine to prevent infection of chimpanzees by an HIV-1 subtype E strain.
Flow cytometric assays for monitoring production of recombinant HIV-1 gp160 in insect cells infected with a baculovirus expression vector.
Functional roles of the V3 hypervariable region of HIV-1 gp160 in the processing of gp160 and in the formation of syncytia in CD4+ cells.
Genetic and neutralization properties of subtype C human immunodeficiency virus type 1 molecular env clones from acute and early heterosexually acquired infections in Southern Africa.
HIV infection of monocytic cells: rôle of antibody-mediated virus binding to Fc-gamma receptors.
HIV-1 neutralizing antibodies in the genital and respiratory tracts of mice intranasally immunized with oligomeric gp160.
Human immunodeficiency virus type 1 env clones from acute and early subtype B infections for standardized assessments of vaccine-elicited neutralizing antibodies.
Identifiable biomarker and treatment development using HIV-1 long term non-progressor sera.
Immunisation with gp160 in HIV-1 infection.
Immunization of chimpanzees with recombinant gp160, but not infection with human immunodeficiency virus type 1, induces envelope-specific Th1 memory cells.
Impaired development of HIV-1 gp160-specific CD8(+) cytotoxic T cells by a delayed switch from Th1 to Th2 cytokine phenotype in mice with Helicobacter pylori infection.
Induction of humoral and cell-mediated anti-human immunodeficiency virus (HIV) responses in HIV sero-negative volunteers by immunization with recombinant gp160.
Induction of neutralizing antibodies against human immunodeficiency virus type 1 using synthetic peptide constructs containing an immunodominant T-helper cell determinant from vpr.
Infection of human monocyte-derived macrophages by human immunodeficiency virus mediated by cell-to-cell transmission.
Inhibition of gp160 and CD4 maturation in U937 cells after both defective and productive infections by human immunodeficiency virus type 1.
Inhibition of HIV-1 infection by an intramolecular antisense peptide to T20 in gp160.
Inhibition of HIV-1 infection by synthetic peptides derived CCR5 fragments.
Insensitivity of Paediatric HIV-1 Subtype C Viruses to Broadly Neutralising Monoclonal Antibodies Raised against Subtype B.
Interaction of mannose-binding lectin with HIV type 1 is sufficient for virus opsonization but not neutralization.
Interactive laser cytometric analysis of retroviral protein expression in HIV-infected lymphocytic cell lines.
Long-term increase of CD4(+) central memory cells in HIV-1-infected individuals by therapeutic HIV-1 rgp160 immunization.
Mucosal and systemic immune responses to a human immunodeficiency virus type 1 epitope induced upon vaginal infection with a recombinant influenza A virus.
Mucosal immunization with HIV-1 peptide vaccine induces mucosal and systemic cytotoxic T lymphocytes and protective immunity in mice against intrarectal recombinant HIV-vaccinia challenge.
Persistent infection by Helicobacter pylori down-modulates virus-specific CD8+ cytotoxic T cell response and prolongs viral infection.
Polyarginine inhibits gp160 processing by furin and suppresses productive human immunodeficiency virus type 1 infection.
Processing and routage of HIV glycoproteins by furin to the cell surface.
Protection of chimpanzees from infection by HIV-1 after vaccination with recombinant glycoprotein gp120 but not gp160.
Protection of macaques against intrarectal infection by a combination immunization regimen with recombinant simian immunodeficiency virus SIVmne gp160 vaccines.
Protection of vaccinia-primed macaques against SIVmne infection by combination immunization with recombinant vaccinia virus and SIVmne gp160.
Recombinant rabies virus as potential live-viral vaccines for HIV-1.
Reduced virus load in rhesus macaques immunized with recombinant gp160 and challenged with simian immunodeficiency virus.
Relevance of the antibody response against human immunodeficiency virus type 1 envelope to vaccine design.
Repeated immunization with recombinant gp160 human immunodeficiency virus (HIV) envelope protein in early HIV-1 infection: evaluation of the T cell proliferative response.
Replication of human immunodeficiency virus in two T-cell lines and their application as antigens for immunofluorescence.
Resistance to human immunodeficiency virus 1 infection of SCID mice reconstituted with peripheral blood leukocytes from donors vaccinated with vaccinia gp160 and recombinant gp160.
Retroviral vector-mediated expression in primary human T cells of an endoplasmic reticulum-retained CD4 chimera inhibits human immunodeficiency virus type-1 replication.
Role of immune responses against the envelope and the core antigens of simian immunodeficiency virus SIVmne in protection against homologous cloned and uncloned virus challenge in Macaques.
Role of nitric oxide in the promoting effect of HIV type 1 infection and of gp120 envelope glycoprotein on interleukin 4-induced IgE production by normal human mononuclear cells.
Role of the HIV type 1 glycoprotein 120 V3 loop in determining coreceptor usage.
Safety and immunogenicity of a fully glycosylated recombinant gp160 human immunodeficiency virus type 1 vaccine in subjects at low risk of infection. National Institute of Allergy and Infectious Diseases AIDS Vaccine Evaluation Group Network.
Safety and immunogenicity of ALVAC vCP1452 and recombinant gp160 in newly human immunodeficiency virus type 1-infected patients treated with prolonged highly active antiretroviral therapy.
Studies of antibody-dependent enhancement of human immunodeficiency virus (HIV) type 1 infection mediated by Fc receptors using sera from recipients of a recombinant gp160 experimental HIV-1 vaccine.
The V1 region of gp120 is preferentially selected during SIV/HIV transmission and is indispensable for envelope function and virus infection.
Therapeutic immunisation with recombinant gp160 in HIV-1 infection: a randomised double-blind placebo-controlled trial. Nordic VAC-04 Study Group.
Topological analysis of HIV-1 glycoproteins expressed in situ on virus surfaces reveals tighter packing but greater conformational flexibility than for soluble gp120.
Vaccination of vaccinia-naive adults with human immunodeficiency virus type 1 gp160 recombinant vaccinia virus in a blinded, controlled, randomized clinical trial. The AIDS Vaccine Clinical Trials Network.
Vaccine-induced protection of chimpanzees against infection by a heterologous human immunodeficiency virus type 1.
[Pathological cleavage of human immunodeficiency virus gp160 protein in infected cells as a probable factor for infection becoming chronic]
Infertility
[Results of fetal monitoring in pregnancy with enzymatic and neuroendocrinologic risk factors]
Influenza, Human
Co-immunization with plasmid IL-12 generates a strong T-cell memory response in mice.
Immunization with subunit human immunodeficiency virus vaccine generates stronger T helper cell immunity than natural infection.
Improved cell-mediated immune responses in HIV-1-infected asymptomatic individuals after immunization with envelope glycoprotein gp160.
Induction of CD8+ cytotoxic T cells by immunization with purified HIV-1 envelope protein in ISCOMs.
Interleukin-2 production used to detect antigenic peptide recognition by T-helper lymphocytes from asymptomatic HIV-seropositive individuals.
Membrane anchorage of gp160 is necessary and sufficient to prevent CD4 transport to the cell surface.
Mucosal and systemic immune responses to a human immunodeficiency virus type 1 epitope induced upon vaginal infection with a recombinant influenza A virus.
Recombinant vaccinia viruses expressing an immunodominant epitope of HIV-1 envelope protein within an influenza hemagglutinin cassette predominantly prime epitope-specific CD8(+) CTL.
T cell responses to recall antigens, alloantigen, and mitogen of HIV-infected patients receiving long-term combined antiretroviral therapy.
Virus membrane fusion proteins: biological machines that undergo a metamorphosis.
Insulin Resistance
Circulating IRAPe, Irisin, and IL-34 in Relation to Insulin Resistance in Patients With Type 2 Diabetes.
Initial entry of IRAP into the insulin-responsive storage compartment occurs prior to basal or insulin-stimulated plasma membrane recycling.
Ischemic Stroke
Insulin-Regulated Aminopeptidase Deficiency Provides Protection against Ischemic Stroke in Mice.
Kidney Neoplasms
Cell surface antigens of human renal cancer defined by mouse monoclonal antibodies: identification of tissue-specific kidney glycoproteins.
Leishmaniasis
Expression in Escherichia coli, purification and kinetic characterization of LAPLm, a Leishmania major M17-aminopeptidase.
Leukemia
In vitro and in vivo cytotoxic activity of anti-human leukemia monoclonal antibodies SN5c and SN6 daunorubicin conjugates.
Leukemia, T-Cell
Complex-type N-linked oligosaccharides of gp120 from human immunodeficiency virus type 1 contain sulfated N-acetylglucosamine.
Liver Diseases
Acute presentation of gestational diabetes insipidus with pre-eclampsia complicated by cerebral vasoconstriction: A case report and review of the published work.
Gestational diabetes insipidus and intrauterine fetal death of monochorionic twins.
Recurrent pregnancy-induced diabetes insipidus in a woman with hemochromatosis.
Lung Neoplasms
Correspondence re: Yasuyuki Sugiyama et al., Selective growth inhibition of human lung cancer cell lines bearing a surface glycoprotein gp160 by 125I-labeled anti-gp160 monoclonal antibody.
Selective growth inhibition of human lung cancer cell lines bearing a surface glycoprotein gp160 by 125I-labeled anti-gp160 monoclonal antibody.
Mastocytoma
The site of administration influences both the type and the magnitude of the immune response induced by DNA vaccine electroporation.
Measles
A chimeric measles virus with a lentiviral envelope replicates exclusively in CD4+/CCR5+ cells.
Improved cell-mediated immune responses in HIV-1-infected asymptomatic individuals after immunization with envelope glycoprotein gp160.
Melanoma
From putative brain tumor marker to high cognitive abilities: Emerging roles of a disintegrin and metalloprotease (ADAM) 12 in the brain.
Memory Disorders
A role for the angiotensin AT4 receptor subtype in overcoming scopolamine-induced spatial memory deficits.
Contributions of the brain angiotensin IV-AT4 receptor subtype system to spatial learning.
Forebrain neurone-specific deletion of insulin-regulated aminopeptidase causes age related deficits in memory.
Phenylalanine-544 plays a key role in substrate and inhibitor binding by providing a hydrophobic packing point at the active site of insulin-regulated aminopeptidase.
Regulation of insulin-regulated membrane aminopeptidase activity by its C-terminal domain.
The angiotensin AT4 receptor subtype as a target for the treatment of memory dysfunction associated with Alzheimer's disease.
Metabolic Diseases
Vasopressin inactivation: Role of insulin-regulated aminopeptidase.
Myoma
[The significance of serum leucine aminopeptidase (P-LAP) determination in the gynecological malignancies]
Neoplasm Metastasis
Novel Human Aminopeptidase N Inhibitors: Discovery and Optimization of Subsite Binding Interactions.
Neoplasms
A model for CD8+ CTL tumor immunosurveillance and regulation of tumor escape by CD4 T cells through an effect on quality of CTL.
Aminopeptidase A expression and enzymatic activity in primary human renal cancers.
Antiproliferative effects of palladium(II) complexes of 5-nitrosopyrimidines and interactions with the proteolytic regulatory enzymes of the renin-angiotensin system in tumoral brain cells.
Cell surface glycoprotein associated with human lung tumors that is similar to but distinct from the epidermal growth factor receptor.
Comparative study to evaluate the effect of l-carnitine plus glimepiride versus glimepiride alone on insulin resistance in type 2 diabetic patients.
Effect of a recombinant HIV gp160 vaccine on monokine production.
Effects of ligands or substrate of insulin-regulated aminopeptidase (IRAP) on trophoblast invasion.
Enhanced HIV-1 envelope-tumor protection by a recombinant vaccinia virus expressing anchored HIV-1 gp120 lacking gp41.
Essential role of placental leucine aminopeptidase in gynecologic malignancy.
Expression of oncodevelopmental gene products by human tumor cells in culture.
Expression of placental leucine aminopeptidase and adipocyte-derived leucine aminopeptidase in human normal and malignant invasive trophoblastic cells.
Granule-dependent mechanisms of lysis are defective in CD8 T cells of HIV-infected, antiretroviral therapy-treated individuals.
In vitro and in vivo cytotoxic activity of anti-human leukemia monoclonal antibodies SN5c and SN6 daunorubicin conjugates.
Insulin-regulated aminopeptidase/placental leucil Aminopeptidase (IRAP/P-lAP) and angiotensin IV-forming activities are modified in serum of rats with breast cancer induced by N-methyl-nitrosourea.
Morphology surface of a mouse plasmacytoma (LPC-1) showing cyclic resistance to immune lysis.
Novel Human Aminopeptidase N Inhibitors: Discovery and Optimization of Subsite Binding Interactions.
Placental leucine aminopeptidase (P-LAP) and glucose transporter 4 (GLUT4) expression in benign, borderline, and malignant ovarian epithelia.
Primary Adrenal Angiosarcoma: A Rare and Potentially Misdiagnosed Tumor.
Regulatory role of membrane-bound peptidases in the progression of gynecologic malignancies.
Selective growth inhibition of human lung cancer cell lines bearing a surface glycoprotein gp160 by 125I-labeled anti-gp160 monoclonal antibody.
Serum cystine aminopeptidase and leucine aminopeptidase activity in women with benign and malignant uterine and ovarian tumors.
Serum oxytocinase activity is related to tumor growth parameters in N-methyl nitrosourea induced rat breast cancer.
The mapping of HIV-1 gp160 epitopes required for interleukin-1 and tumor necrosis factor alpha production in glial cells.
The transmembrane domain of vesicular stomatitis virus glycoprotein suffices to anchor HIV-1 envelope gp120 expressed by a recombinant vaccinia virus.
Trophoblastic proteins as tumor markers in nonseminomatous germ cell tumors.
[A case of pineoblastoma successfully treated with surgery, combined chemotherapy of cisplatin and etoposide, and radiotherapy]
[Leucyl-aminopeptidase, thioacetic acid esterase and E 600-resistant esterase in cervix uteri cancer]
[The significance of serum leucine aminopeptidase (P-LAP) determination in the gynecological malignancies]
Neoplasms, Germ Cell and Embryonal
Trophoblastic proteins as tumor markers in nonseminomatous germ cell tumors.
Neuroblastoma
Differential Effects of Doxazosin on Renin-Angiotensin-System-Regulating Aminopeptidase Activities in Neuroblastoma and Glioma Tumoral Cells.
Newcastle Disease
Comparative Immunogenicity of HIV-1 gp160, gp140 and gp120 Expressed by Live Attenuated Newcastle Disease Virus Vector.
Enhanced Immune Responses to HIV-1 Envelope Elicited by a Vaccine Regimen Consisting of Priming with Newcastle Disease Virus Expressing HIV gp160 and Boosting with gp120 and SOSIP gp140 Proteins.
Modified Newcastle Disease virus as an improved vaccine vector against Simian Immunodeficiency virus.
Mucosal Immunization with Newcastle Disease Virus Vector Coexpressing HIV-1 Env and Gag Proteins Elicits Potent Serum, Mucosal, and Cellular Immune Responses That Protect against Vaccinia Virus Env and Gag Challenges.
Retraction: Comparative immunogenicity of HIV-1 gp160, gp140 and gp120 expressed by live attenuated newcastle disease virus vector.
Obesity
Hypooxytocinaemia in obese Zucker rats relates to oxytocin degradation in liver and adipose tissue.
Insulin-regulated aminopeptidase in adipocyte is Cys-specific and affected by obesity.
Obstetric Labor, Premature
A new approach regarding the treatment of preeclampsia and preterm labor.
Maternal serum placental leucine aminopeptidase (P-LAP)/oxytocinase and preterm delivery.
New insights into the role of aminopeptidases in the treatment for both preeclampsia and preterm labor.
New Insights into the Role of Sex Steroid Hormones in Pregnancy: Possible Therapeutic Approach by Sex Steroid Hormones for the Treatment of Both Preeclampsia and Preterm Labor.
[Cystine aminopeptidase and oxytocin in the plasma of pregnant patients with premature labor]
[Ethanol perfusions during threatened premature labor. Special study of oxytocinase activity]
Ovarian Neoplasms
CircLNPEP promotes the progression of ovarian cancer through regulating miR-876-3p/ WNT5A axis.
Early primary diagnosis of ovarian cancer and detection of recurrence by serum cystine aminopeptidase assay.
Placental leucine aminopeptidase (P-LAP) and glucose transporter 4 (GLUT4) expression in benign, borderline, and malignant ovarian epithelia.
Regulatory role of membrane-bound peptidases in the progression of gynecologic malignancies.
[The significance of serum leucine aminopeptidase (P-LAP) determination in the gynecological malignancies]
Parkinson Disease
Lateralized response of oxytocinase activity in the medial prefrontal cortex of a unilateral rat model of Parkinson's disease.
Persistent Infection
An evolutionarily conserved splice generates a secreted env-Bet fusion protein during human foamy virus infection.
Placental Insufficiency
Cystyl aminopeptidase in maternal serum for the antenatal recognition of fetal growth retardation.
[DETERMINATION OF SERUM OXYTOCINASE IN PLACENTAL INSUFFICIENCY AND FETAL DEATH "IN UTERO".]
Pneumonia, Pneumocystis
[A case of HIV-1 infection that showed Western blot analysis for HIV-1 negative after antiretroviral therapy]
Polyhydramnios
Severe hydramnios and preterm delivery in association with transient maternal diabetes insipidus.
Polyuria
Gestational diabetes insipidus: Diagnosis and management.
Severe hydramnios and preterm delivery in association with transient maternal diabetes insipidus.
Usefulness of anti-rabphilin-3A antibodies for diagnosing central diabetes insipidus in the third trimester of pregnancy.
Pre-Eclampsia
A hypothesis on the role of antidiuretic hormone in preeclampsia.
A new approach regarding the treatment of preeclampsia and preterm labor.
A proposed relationship between vasopressinase altered vasopressin and preeclampsia.
Alteration of circulating Placental Leucine Aminopeptidase (P-LAP) activity in preeclampsia.
Decreased levels of amniotic fluid oxytocinase activity in preeclampsia.
Effects of placental proteases on maternal and fetal blood pressure in normal pregnancy and preeclampsia.
Gene regulation and physiological function of placental leucine aminopeptidase/oxytocinase during pregnancy.
Genetic association of ERAP1 and ERAP2 with eclampsia and preeclampsia in northeastern Brazilian women.
Insulin-regulated aminopeptidase deficiency impairs cardiovascular adaptations and placental development during pregnancy.
Loss of biological activity of arginine vasopressin during its degradation by vasopressinase from pregnancy serum.
New insights into the role of aminopeptidases in the treatment for both preeclampsia and preterm labor.
New Insights into the Role of Sex Steroid Hormones in Pregnancy: Possible Therapeutic Approach by Sex Steroid Hormones for the Treatment of Both Preeclampsia and Preterm Labor.
OS060. Exercise training promotes placental growth and development in an animal model of preeclampsia superimposed on chronic hypertension.
Plasma angiotensin I and serum placental leucine aminopeptidase (P-LAP) in pre-eclampsia.
Plasma angiotensin I concentration and serum placental leucine aminopeptidase (P-LAP) activities in puerperal hypertension.
PREECLAMPSIA ASSOCIATED WITH DECREASE IN SERUM OXYTOCINASE.
Serum Vasopressinase and Platelet Responses to Arginine Vasopressin in Normal Pregnancy, Pregnancy-induced Hypertension and Pre-eclampsia.
The role of LNPEP and ANPEP gene polymorphisms in the pathogenesis of pre-eclampsia.
Transient diabetes insipidus in a post-partum woman with pre-eclampsia associated with residual placental vasopressinase activity.
Vasopressin inactivation: Role of insulin-regulated aminopeptidase.
[Diabetes insipidus with a hypothalamo-hypophyseal morphologic anomaly during a pregnancy]
[Estimation of placental leucine aminopeptidase (P-LAP) in pregnancy sera]
[Serum oxytocinase in prolonged pregnancy and pre-eclampsia]
Precursor Cell Lymphoblastic Leukemia-Lymphoma
In vitro and in vivo cytotoxic activity of anti-human leukemia monoclonal antibodies SN5c and SN6 daunorubicin conjugates.
Pregnancy Complications
[Oxytocinase activity in pregnancy complications]
[Oxytocinase in pregnancy complications]
Pregnancy, Ectopic
Predictive value analysis of measurements of human chorionic gonadotropin, pregnancy specific beta 1-glycoprotein, placental lactogen, and cystine aminopeptidase for the diagnosis of ectopic pregnancy.
[Placental lactogen level and activity of oxytocinase, beta-glucuronidase and thermostable alkaline phosphatase isoenzyme in blood serum of women with ectopic pregnancy]
Pregnancy, High-Risk
Colpocytograms and maternal serum placental cystine aminopeptidase, tissue cystine aminopeptidase, alkaline phosphatase and heat stable alkaline phosphatase activity in monitoring the last four weeks before delivery in high-risk pregnancy.
Comparative prognostic value of serum placental and tissue oxytocinase, alkaline phosphatase and its heat-stable fraction in pregnancy at neuroendocrinological risk.
[Serial determinations of serum oxytocinase and ultrasonic biparietal cephalometry in normal and high-risk pregnancies]
Pregnancy, Prolonged
PROLONGED PREGNANCY ASSOCIATED WITH INCREASE IN SERUM OXYTOCINASE.
[Activity of oxytocinase, leucine aminopeptidase and glutamyl-transferase in term pregnancy and prolonged pregnancy]
[Estimation of placental leucine aminopeptidase (P-LAP) in pregnancy sera]
[Role of oxytocinase (CAP) in prolonged pregnancy]
[Serum oxytocinase in prolonged pregnancy and pre-eclampsia]
[The activity of serum oxytocinase in prolonged pregnancy]
[The behavior of serum oxytocinase in cases of prolonged pregnancy]
[The effect of estrogen administration on the level of serum oxytocinase in prolonged pregnancy]
Proteinuria
Immunization with recombinant gp160 prolongs the survival of HIV-1 transgenic mice.
Psoriasis
Identification of a Missense Variant in LNPEP that Confers Psoriasis Risk.
Rabies
Expression and immunogenicity of human immunodeficiency virus type 1 Gag expressed by a replication-competent rhabdovirus-based vaccine vector.
Improved antigenicity of the HIV env protein by cleavage site removal.
Rhabdovirus-based vectors with human immunodeficiency virus type 1 (HIV-1) envelopes display HIV-1-like tropism and target human dendritic cells.
Seizures
Deletion of insulin-regulated aminopeptidase in mice decreases susceptibility to pentylenetetrazol-induced generalized seizures.
Involvement of the somatostatin-2 receptor in the anti-convulsant effect of angiotensin IV against pilocarpine-induced limbic seizures in rats.
Trans-Modulation of the Somatostatin Type 2A Receptor Trafficking by Insulin-Regulated Aminopeptidase Decreases Limbic Seizures.
Sepsis
Vasopressin inactivation: Role of insulin-regulated aminopeptidase.
Shock, Septic
A PCR-RFLP method for detection of the LNPEP encoding human insulin-regulated aminopeptidase (IRAP) rs4869317 polymorphism.
Depletion of neurohypophyseal content of vasopressin in septic shock.
Leucyl/cystinyl aminopeptidase (LNPEP) gene variants in septic shock.
Smallpox
Safety of and immunological response to a recombinant vaccinia virus vaccine expressing HIV envelope glycoprotein.
Stillbirth
Urinary sex steroid hormone and placental leucine aminopeptidase concentration differences between live births and stillbirth of Bornean orangutans (Pongo pygmaeus).
Stomatitis
The transmembrane domain of vesicular stomatitis virus glycoprotein suffices to anchor HIV-1 envelope gp120 expressed by a recombinant vaccinia virus.
Tetanus
A Phase I, placebo-controlled trial of multi-dose recombinant human interleukin-12 in patients with HIV infection.
Expansion of restricted cellular immune responses to HIV-1 envelope by vaccination: IL-7 and IL-12 differentially augment cellular proliferative responses to HIV-1.
Improved cell-mediated immune responses in HIV-1-infected asymptomatic individuals after immunization with envelope glycoprotein gp160.
Use of particulate forms of protein antigens to increase the sensitivity of antigen-specific proliferation assays.
Thrombosis
A clinical approach in regression of glomerulosclerosis.
Ablation of Angiotensin IV Receptor Attenuates Hypofibrinolysis via PAI-1 Downregulation and Reduces Occlusive Arterial Thrombosis.
Angiotensin II-Mediated Microvascular Thrombosis.
Current Trends on Glomerulosclerosis Regression.
Toxemia
A proposed relationship between vasopressinase altered vasopressin and preeclampsia.
Toxoplasmosis
X-ray crystal structure and specificity of the Toxoplasma gondii ME49 TgAPN2.
Trophoblastic Neoplasms
Expression of placental leucine aminopeptidase and adipocyte-derived leucine aminopeptidase in human normal and malignant invasive trophoblastic cells.
Trophoblastic Tumor, Placental Site
Expression of placental leucine aminopeptidase and adipocyte-derived leucine aminopeptidase in human normal and malignant invasive trophoblastic cells.
Tuberculosis, Pulmonary
[A case of HIV-1 infection that showed Western blot analysis for HIV-1 negative after antiretroviral therapy]
Uterine Cervical Neoplasms
Regulatory role of membrane-bound peptidases in the progression of gynecologic malignancies.
Vaccinia
A 2-year follow-up of an anti-HIV immune reaction in HIV-1 gp160-immunized healthy seronegative humans: evidence for persistent cell-mediated immunity.
A group specific anamnestic immune reaction against HIV-1 induced by a candidate vaccine against AIDS.
A model for CD8+ CTL tumor immunosurveillance and regulation of tumor escape by CD4 T cells through an effect on quality of CTL.
Alteration of V3 loop context within the envelope of human immunodeficiency virus type 1 enhances neutralization.
An immunodominant epitope of the human immunodeficiency virus envelope glycoprotein gp160 recognized by class I major histocompatibility complex molecule-restricted murine cytotoxic T lymphocytes.
Antibodies directed against the MHC-I molecule H-2Dd complexed with an antigenic peptide: similarities to a T cell receptor with the same specificity.
Antibodies to soluble CD4 in HIV-1-infected individuals.
Antibodies to the putative SIV infection-enhancing domain diminish beneficial effects of an SIV gp160 vaccine in rhesus macaques.
Antibody-dependent cell-mediated cytotoxicity directed by a human monoclonal antibody reactive with gp120 of HIV-1.
Antibody-dependent cellular cytotoxicity against HIV-1 in sera of immunized chimpanzees.
Antigenic specificity of antibody-dependent cell-mediated cytotoxicity directed against human immunodeficiency virus in antibody-positive sera.
Augmentation of human immunodeficiency virus type 1 neutralizing antibody by priming with gp160 recombinant vaccinia and boosting with rgp160 in vaccinia-naive adults. The NIAID AIDS Vaccine Clinical Trials Network.
Biological properties of recombinant HIV envelope synthesized in CHO glycosylation-mutant cell lines.
Brucella abortus conjugated with a gp120 or V3 loop peptide derived from human immunodeficiency virus (HIV) type 1 induces neutralizing anti-HIV antibodies, and the V3-B. abortus conjugate is effective even after CD4+ T-cell depletion.
Brucella abortus conjugated with a peptide derived from the V3 loop of human immunodeficiency virus (HIV) type 1 induces HIV-specific cytotoxic T-cell responses in normal and in CD4+ cell-depleted BALB/c mice.
Calcium requirement and inhibitor spectrum for intracellular HIV type 1 gp160 processing in cultured HeLa cells and CD4+ lymphocytes: similarity to those of viral envelope glycoprotein maturase.
Candidate HIV type 1 multideterminant cluster peptide-P18MN vaccine constructs elicit type 1 helper T cells, cytotoxic T cells, and neutralizing antibody, all using the same adjuvant immunization.
Characterization and large production of human monoclonal antibodies against the HIV-1 envelope.
Co-administration of viral vector-based vaccines suppresses antigen-specific effector CD8 T cells.
Coadministration of HIV vaccine vectors with vaccinia viruses expressing IL-15 but not IL-2 induces long-lasting cellular immunity.
Competitive inhibition in vivo and skewing of the T cell repertoire of antigen-specific CTL priming by an anti-peptide-MHC monoclonal antibody.
Conglutinin binds the HIV-1 envelope glycoprotein gp 160 and inhibits its interaction with cell membrane CD4.
Cross-neutralizing antibodies in rabbits immunized with HIV-1 gp160 purified from simian cells infected with a recombinant vaccinia virus.
Cross-neutralizing antibodies to HIV-1 in mice after immunization with gp160 iscoms. Dissection of the immune response.
Cross-protection in NYVAC-HIV-1-immunized/HIV-2-challenged but not in NYVAC-HIV-2-immunized/SHIV-challenged rhesus macaques.
Cross-reactive response to human immunodeficiency virus type 1 (HIV-1) gp120 and HLA class I heavy chains induced by receipt of HIV-1-derived envelope vaccines.
Cutting edge: a single MHC class Ia is sufficient for CD8 memory T cell differentiation.
Cytotoxic T cell repertoire selection. A single amino acid determines alternative class I restriction.
Cytotoxic T lymphocytes specific for HIV-1 gp160 antigen and synthetic P18IIIB peptide in an HLA-A11-immunized individual.
Determinants of antibody response after recombinant gp160 boosting in vaccinia-naive volunteers primed with gp160-recombinant vaccinia virus. The National Institute of Allergy and Infectious Diseases AIDS Vaccine Clinical Trials Network.
Differences in the antibody response to human immunodeficiency virus-1 envelope glycoprotein (gp160) in infected laboratory workers and vaccinees.
Effect of a glucosidase inhibitor on the bioactivity and immunoreactivity of human immunodeficiency virus type 1 envelope glycoprotein.
Effect of alpha-1 antitrypsin Portland variant (alpha 1-PDX) on HIV-1 replication.
Effect of nonprotective vaccination on antibody response to subsequent human immunodeficiency virus infection.
Effect of the V3 loop deletion of envelope glycoprotein on cellular responses and protection against challenge with recombinant vaccinia virus expressing gp160 of primary human immunodeficiency virus type 1 isolates.
Enhanced HIV-1 envelope-tumor protection by a recombinant vaccinia virus expressing anchored HIV-1 gp120 lacking gp41.
Enhanced immunity to human immunodeficiency virus (HIV) envelope elicited by a combined vaccine regimen consisting of priming with a vaccinia recombinant expressing HIV envelope and boosting with gp160 protein.
Enhanced proteolytic processing of the human immunodeficiency virus type 1 envelope protein in murine Ltk(-) cells.
Envelope protein and p18(IIIB) peptide recognized by cytotoxic T lymphocytes from humans immunized with human immunodeficiency virus envelope.
Evaluation of protective efficacy of recombinant subunit vaccines against simian immunodeficiency virus infection of macaques.
Functional role of the glycan cluster of the human immunodeficiency virus type 1 transmembrane glycoprotein (gp41) ectodomain.
Functional roles of the V3 hypervariable region of HIV-1 gp160 in the processing of gp160 and in the formation of syncytia in CD4+ cells.
Gene gun-based nucleic acid immunization alone or in combination with recombinant vaccinia vectors suppresses virus burden in rhesus macaques challenged with a heterologous SIV.
Helminth infection results in decreased virus-specific CD8+ cytotoxic T-cell and Th1 cytokine responses as well as delayed virus clearance.
HIV-1 env, nef, and gag-specific T-cell immunity in mice: conserved epitopes in nef p27 and gag p25 proteins.
HIV-specific T lymphocyte immunity in mice immunized with a recombinant vaccinia virus.
Immunisation of macaques with SIV env recombinants: specificity of T cell and antibody responses and evaluation of protective efficacy.
Immunization strategies to augment oral vaccination with DNA and viral vectors expressing HIV envelope glycoprotein.
Impaired development of HIV-1 gp160-specific CD8(+) cytotoxic T cells by a delayed switch from Th1 to Th2 cytokine phenotype in mice with Helicobacter pylori infection.
Improved antigenicity of the HIV env protein by cleavage site removal.
Improved immunogenicity of recombinant vaccinia virus-anchored gp120 lacking gp41.
Increased susceptibility of mice infected with Schistosoma mansoni to recombinant vaccinia virus: association of viral persistence with egg granuloma formation.
Induction of a major histocompatibility complex class I-restricted cytotoxic T-lymphocyte response to a highly conserved region of human immunodeficiency virus type 1 (HIV-1) gp120 in seronegative humans immunized with a candidate HIV-1 vaccine.
Induction of a mucosal cytotoxic T-lymphocyte response by intrarectal immunization with a replication-deficient recombinant vaccinia virus expressing human immunodeficiency virus 89.6 envelope protein.
Induction of apoptosis-resistant and TGF-?-insensitive murine CD8(+) cytotoxic T lymphocytes specific for HIV-1 gp160.
Induction of rapid apoptosis for class I MHC molecule-restricted CD8+ HIV-1 gp160-specific murine activated CTLs by free antigenic peptide in vivo.
Kex2p: a model for cellular endoprotease processing human immunodeficiency virus type 1 envelope glycoprotein precursor.
Large-scale production and purification of a vaccinia recombinant-derived HIV-1 gp160 and analysis of its immunogenicity.
Lymphoproliferative response to synthetic V3 loop P18 peptide and HIV-1 envelope glycoprotein among individuals immunized with gp160 candidate vaccines.
M cell DNA vaccination for CTL immunity to HIV.
Mucosal immunization with HIV-1 peptide vaccine induces mucosal and systemic cytotoxic T lymphocytes and protective immunity in mice against intrarectal recombinant HIV-vaccinia challenge.
Mucosal vaccination overcomes the barrier to recombinant vaccinia immunization caused by preexisting poxvirus immunity.
Multigene DNA priming-boosting vaccines protect macaques from acute CD4+-T-cell depletion after simian-human immunodeficiency virus SHIV89.6P mucosal challenge.
Murine monoclonal antibodies biologically active against the amino region of HIV-1 gp120: isolation and characterization.
Neutralizing antibodies against HIV-1 BRU and SF2 isolates generated in mice immunized with recombinant vaccinia virus expressing HIV-1 (BRU) envelope glycoproteins and boosted with homologous gp160.
Oral DNA vaccination promotes mucosal and systemic immune responses to HIV envelope glycoprotein.
Persistent infection by Helicobacter pylori down-modulates virus-specific CD8+ cytotoxic T cell response and prolongs viral infection.
Presence of cross-reactive antibody between human immunodeficiency virus (HIV) and platelet glycoproteins in HIV-related immune thrombocytopenic purpura.
Production and characterization of a human monoclonal antibody, reactive with a conserved epitope on gp41 of human immunodeficiency virus type I.
Production of a novel antigen by conjugation of HIV-1 to Brucella abortus: studies of immunogenicity, isotype analysis, T-cell dependency, and syncytia inhibition.
Production of long-lived neutralizing antibodies to HIV-1 IIIB in mice with a vaccinia recombinant virus-infected cell vaccine expressing gp160.
Protection of macaques against SIV infection by subunit vaccines of SIV envelope glycoprotein gp160.
Protection of vaccinia-primed macaques against SIVmne infection by combination immunization with recombinant vaccinia virus and SIVmne gp160.
Purification and characterization of a Ca2+-independent endoprotease activity from peripheral blood lymphocytes: involvement in HIV-1 gp160 maturation.
Reciprocal cytotoxic T lymphocyte cross-reactivity interactions between two major epitopes within HIV-1 gp160.
Recombinant vaccinia viruses expressing an immunodominant epitope of HIV-1 envelope protein within an influenza hemagglutinin cassette predominantly prime epitope-specific CD8(+) CTL.
Reduced cell surface expression of processed human immunodeficiency virus type 1 envelope glycoprotein in the presence of Nef.
Reduced virus load in rhesus macaques immunized with recombinant gp160 and challenged with simian immunodeficiency virus.
Removal of a single N-linked glycan in human immunodeficiency virus type 1 gp120 results in an enhanced ability to induce neutralizing antibody responses.
Resistance to human immunodeficiency virus 1 infection of SCID mice reconstituted with peripheral blood leukocytes from donors vaccinated with vaccinia gp160 and recombinant gp160.
Response of monkeys to vaccination with recombinant vaccinia virus which coexpress HIV gp160 and human interleukin-2.
Role of HIV-1 envelope V3 loop cleavage in cell tropism.
Role of immune responses against the envelope and the core antigens of simian immunodeficiency virus SIVmne in protection against homologous cloned and uncloned virus challenge in Macaques.
Safety and immunogenicity of a fully glycosylated recombinant gp160 human immunodeficiency virus type 1 vaccine in subjects at low risk of infection. National Institute of Allergy and Infectious Diseases AIDS Vaccine Evaluation Group Network.
Safety of and immunological response to a recombinant vaccinia virus vaccine expressing HIV envelope glycoprotein.
Serum antibodies to HIV-1 in recombinant vaccinia virus recipients boosted with purified recombinant gp160. NIAID AIDS Vaccine Clinical Trials Network.
Several antigenic determinants exposed on the gp120 moiety of HIV-1 gp160 are hidden on the mature gp120.
Stable expression of the human immunodeficiency virus type 1 envelope glycoprotein in transfected L cells.
Sulfation of the human immunodeficiency virus envelope glycoprotein.
Syngeneic adoptive transfer of anti-human immunodeficiency virus (HIV-1)-primed lymphocytes from a vaccinated HIV-seronegative individual to his HIV-1-infected identical twin.
Technology evaluation: HIVAC-1e.
The appearance of escape variants in vivo does not account for the failure of recombinant envelope vaccines to protect against simian immunodeficiency virus.
The enhanced immune response to the HIV gp160/LAMP chimeric gene product targeted to the lysosome membrane protein trafficking pathway.
The glycosylation of human immunodeficiency virus type 1 transmembrane glycoprotein (gp41) is important for the efficient intracellular transport of the envelope precursor gp160.
The human immunodeficiency virus type 1 envelope glycoprotein precursor acquires aberrant intermolecular disulfide bonds that may prevent normal proteolytic processing.
The mapping of HIV-1 gp160 epitopes required for interleukin-1 and tumor necrosis factor alpha production in glial cells.
The transmembrane domain of vesicular stomatitis virus glycoprotein suffices to anchor HIV-1 envelope gp120 expressed by a recombinant vaccinia virus.
Theoretical and functional analysis of the SIV fusion peptide.
Transcutaneous immunization induces mucosal CTLs and protective immunity by migration of primed skin dendritic cells.
Vaccination of vaccinia-naive adults with human immunodeficiency virus type 1 gp160 recombinant vaccinia virus in a blinded, controlled, randomized clinical trial. The AIDS Vaccine Clinical Trials Network.
Vaccine-induced antibodies to native and recombinant human immunodeficiency virus type 1 envelope glycoproteins. NIAID AIDS Vaccine Clinical Trials Network.
Virus-Like Particles Displaying Trimeric Simian Immunodeficiency Virus (SIV) Envelope gp160 Enhance the Breadth of DNA/Modified Vaccinia Virus Ankara SIV Vaccine-Induced Antibody Responses in Rhesus Macaques.
[HIV-1 env glycoprotein gp120 and gp160 expressed in vaccinia virus system and their antigenicity analysis]
[The non-replicating recombinant vaccinia virus expressing six genes of HIV-1 can be passaged stably in CEF].
Vesicular Stomatitis
Expression and processing of human immunodeficiency virus type 1 gp160 using the vesicular stomatitis virus New Jersey serotype vector system.
Priming with plasmid DNAs expressing interleukin-12 and simian immunodeficiency virus gag enhances the immunogenicity and efficacy of an experimental AIDS vaccine based on recombinant vesicular stomatitis virus.
Retargeting Oncolytic Vesicular Stomatitis Virus to Human T-Cell Lymphotropic Virus Type 1-Associated Adult T-Cell Leukemia.
Viremia
Evidence for both Intermittent and Persistent Compartmentalization of HIV-1 in the Female Genital Tract.
Lack of in vitro anti-gp160 antibody production is a correlate of nonprogression among HIV type 1-infected individuals.
Virus Diseases
A phase I evaluation of the safety and immunogenicity of vaccination with recombinant gp160 in patients with early human immunodeficiency virus infection. Military Medical Consortium for Applied Retroviral Research.
Helminth infection results in decreased virus-specific CD8+ cytotoxic T-cell and Th1 cytokine responses as well as delayed virus clearance.
Interaction of mannose-binding lectin with HIV type 1 is sufficient for virus opsonization but not neutralization.
Lymphoproliferative response to synthetic V3 loop P18 peptide and HIV-1 envelope glycoprotein among individuals immunized with gp160 candidate vaccines.
Persistent infection by Helicobacter pylori down-modulates virus-specific CD8+ cytotoxic T cell response and prolongs viral infection.
Possible mechanism of action of antiviral proteins from the leaves of Chenopodium album L.
The role of eukaryotic subtilisin-like endoproteases for the activation of human immunodeficiency virus glycoproteins in natural host cells.
Vpu exerts a positive effect on HIV-1 infectivity by down-modulating CD4 receptor molecules at the surface of HIV-1-producing cells.