Reference on EC 3.4.11.22 - aminopeptidase I

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Klionsky, D.J.
Nonclassical protein sorting to the yeast vacuole
J. Biol. Chem.
273
10807-10810
1998
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Martinez, E.; Jimenez, M.A.; Segui-Real, B.; Vandekerckhove, J.; Sandoval, I.V.
Folding of the presequence of yeast pAPI into an amphipathic helix determines transport of the protein from the cytosol to the vacuole
J. Mol. Biol.
267
1124-1138
1997
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Kim, J.; Scott, S.V.; Oda, M.N.; Klionsky, D.J.
Transport of a large oligomeric protein by the cytoplasm to vacuole protein targeting pathway
J. Cell Biol.
137
609-618
1997
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Scott, S.V.; Baba, M.; Ohsumi, Y.; Klionsky, D.J.
Aminopeptidase I is targeted to the vacuole by a nonclassical vesicular mechanism
J. Cell Biol.
138
37-44
1997
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Oda, M.N.; Scott, S.V.; Hefner-Gravink, A.; Caffarelli, A.C.; Klionsky, D.J.
Identification of a cytoplasm to vacuole targeting determinant in aminopeptidase I
J. Cell Biol.
132
999-1010
1996
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Scott, S.V.; Klionsky, D.J.
In vitro reconstitution of cytoplasm to vacuole protein targeting in yeast
J. Cell Biol.
3¦131
1727-1735
1995
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Segui-Real, B.; Martinez, M.; Sandoval, I.V.
Yeast aminopeptidase I is post-translationally sorted from the cytosol to the vacuole by a mechanism mediated by its bipartite N-terminal extension
EMBO J.
14
5476-5484
1995
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Tisljar, U.; Wolf, D.H.
Purification and characterization of the cystinyl bond cleaving yeast aminopeptidase yscXVI
FEBS Lett.
322
191-196
1993
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Moriyasu, Y.; Sakano, K.; Tazawa, M.
Vacuolar/extravacuolar distribution of aminopeptidase in giant alga Chara australis and partial purification of one such enzyme
Plant Physiol.
84
720-725
1987
Chara australis
Manually annotated by BRENDA team
Hetz, G.; Röhm, K.H.
Interaction of chloride with yeast aminopeptidase I. Equilibrium binding studies
Biol. Chem. Hoppe-Seyler
368
63-66
1987
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Röhm., K.H.
Chloride as allosteric effector of yeast aminopeptidase I
Arch. Biochem. Biophys.
239
216-225
1985
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Röhm., K.H.
Metal binding to yeast aminopeptidase I
Eur. J. Biochem.
146
633-639
1985
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Schwencke, J.; Moustacchi, E.
Proteolytic activities in yeast after UV irradiation. I. Variation in proteinase levels in repair proficient Rad+ strains
Mol. Gen. Genet.
185
290-295
1982
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Löffler, H.G.; Röhm.K.H.
Comparative studies on the dodecameric and hexameric forms of yeast aminopeptidase I
Z. Naturforsch. C
34
381-386
1979
Saccharomyces cerevisiae
-
Manually annotated by BRENDA team
Metz, G.; Marx, R.; Röhm, K.H.
The quarternary structure of yeast aminopeptidase I 1. Molecular forms and subunit size
Z. Naturforsch. C
32
929-937
1977
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Metz, G.; Röhm.K.H.
Yeast aminopeptidase I. Chemical composition and catalytic properties
Biochim. Biophys. Acta
429
933-949
1976
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Cueva, R.; Garcia-Alvarez, N.; Suarez-Rendueles, P.
Yeast vacuolar aminopeptidase yscI. Isolation and regulation of the APE1 (LAP4) structural gene
FEBS Lett.
259
125-129
1989
Saccharomyces cerevisiae (P14904), Saccharomyces cerevisiae
Manually annotated by BRENDA team
Bienvenue, D.L.; Gilner, D.; Holz, R.C.
Hydrolysis of thionopeptides by the aminopeptidase from Aeromonas proteolytica: insight into substrate binding
Biochemistry
41
3712-3719
2002
Vibrio proteolyticus
Manually annotated by BRENDA team
Cristofoletti, P.T.; Terra, W.R.
The role of amino acid residues in the active site of a midgut microvillar aminopeptidase from the beetle Tenebrio molitor
Biochim. Biophys. Acta
1479
185-195
2000
Tenebrio molitor
Manually annotated by BRENDA team
Blinkovsky, A.M.; Byun, T.; Brown, K.M.; Golightly, E.J.; Klotz, A.V.
A non-specific aminopeptidase from Aspergillus
Biochim. Biophys. Acta
1480
171-181
2000
Aspergillus oryzae
Manually annotated by BRENDA team
Chien, H.C.R.; Lin, L.L.; Chao, S.H.; Chen, C.C.; Wang, W.C.; Shaw, C.Y.; Tsai, Y.C.; Hu, H.Y.; Hsu, W.H.
Purification, characterization, and genetic analysis of a leucine aminopeptidase from Aspergillus sojae
Biochim. Biophys. Acta
1576
119-126
2002
Aspergillus sojae (Q8J2N2)
Manually annotated by BRENDA team
Bozic, N.; Vuicic, Z.; Nenadovic, V.; Ivanovic, J.
Partial purification and characterization of midgut leucyl aminopeptidase of Morimus funereus (coleoptera: cerambycidae) larvae
Comp. Biochem. Physiol. B
134
231-241
2003
Morimus funereus
Manually annotated by BRENDA team
Kuo, L.Y.; Hwang, G.Y.; Lai, Y.J.; Yang, S.L.; Lin, L.L.
Overexpression, purification, and characterization of the recombinant leucine aminopeptidase II of Bacillus stearothermophilus
Curr. Microbiol.
47
40-45
2003
Geobacillus stearothermophilus, Geobacillus stearothermophilus NIB 8924
Manually annotated by BRENDA team
Byun, T; Tang, M.; Sloma, A.; Brown, K.M.; Marumoto, C.; Fujii, M.; Blinkovsky, A.M.
Aminopeptidase from Sphingomonas capsulata
J. Biol. Chem.
276
17902-17907
2001
Novosphingobium capsulatum
Manually annotated by BRENDA team
Desmarais, W.T.; Bienvenue, D.L.; Bzymek, K.P.; Holz, R.C.; Petsko, G.A.; Ringe, D.
The 1.20 A resolution crystal structure of the aminopeptidase from Aeromonas proteolytica complexed with tris: a tale of buffer inhibition
Structure
10
1063-1072
2002
Vibrio proteolyticus
Manually annotated by BRENDA team
Huston, A.L.; Methe, B.; Deming, J.W.
Purification, characterization, and sequencing of an extracellular cold-active aminopeptidase produced by marine psychrophile Colwellia psychrerythraea strain 34H
Appl. Environ. Microbiol.
70
3321-3328
2004
Colwellia psychrerythraea
Manually annotated by BRENDA team
Nishiwaki, T.; Hayashi, K.
Purification and characterization of an aminopeptidase from the edible basidiomycete Grifola frondosa
Biosci. Biotechnol. Biochem.
65
424-427
2001
Grifola frondosa
Manually annotated by BRENDA team
Caprioglio, D.R.
Yeast aminopeptidases Ape2, Aap1' and Yin7
Handbook of Proteolytic Enzymes (Barrett, J. ; Rawlings, N. D. ; Woessner, J. F. , eds)
1
316-318
2004
Saccharomyces cerevisiae
-
Manually annotated by BRENDA team
Suarez-Rendueles, P.; Bordallo, J.; Cueva, R.
Aminopeptidase I
Handbook of Proteolytic Enzymes (Barrett, J. ; Rawlings, N. D. ; Woessner, J. F. , eds)
1
940-941
2004
Saccharomyces cerevisiae
-
Manually annotated by BRENDA team
Motoshima, H.; Kaminogawa, S.
Bacillus aminopeptidase I
Handbook of Proteolytic Enzymes (Barrett, J. ; Rawlings, N. D. ; Woessner, J. F. , eds)
1
968-970
2004
Geobacillus stearothermophilus
-
Manually annotated by BRENDA team
Byun, T.; Kofod, L.; Blinkovsky, A.
Synergistic action of an X-prolyl dipeptidyl aminopeptidase and a non-specific aminopeptidase in protein hydrolysis
J. Agric. Food Chem.
49
2061-2063
2001
Aspergillus oryzae
Manually annotated by BRENDA team
Noguchi, Y.; Nagata, H.; Koganei, H.; Kodera, Y.; Hiroto, M.; Nishimura, H.; Inada, Y.; Matsushima, A.
Isolation and characterization of aminopeptidase (Jc-peptidase) from Japanese cedar pollen (Cryptomeria japonica)
J. Agric. Food Chem.
50
3540-3543
2002
Cryptomeria japonica
Manually annotated by BRENDA team
Nagata, H.; Takei, T.; Kojima, R.; Kodera, Y.; Nishimura, H.; Inada, Y.; Matsushima, A.
Characteristics of an aminopeptidase from Japanese cedar (Cryptomeria japonica) pollen
J. Agric. Food Chem.
53
5445-5448
2005
Cryptomeria japonica
Manually annotated by BRENDA team
Andrei-Selmer, C.; Knuppel, A.; Satyanarayana, C.; Heese, C.; Schu, P.V.
A new class of mutants deficient in dodecamerization of aminopeptidase 1 and vacuolar transport
J. Biol. Chem.
276
11606-11614
2001
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Desimone, M.; Kruger, M.; Wessel, T.; Wehofsky, M.; Hoffmann, R.; Wagner, E.
Purification and characterization of an aminopeptidase from the chloroplast stroma of barley leaves by chromatographic and electrophoretic methods
J. Chromatogr. B
737
285-293
2000
Hordeum vulgare
Manually annotated by BRENDA team
Millership, J.J.; Chappell, C.; Okhuysen, P.C.; Snowden, K.F.
Characterization of aminopeptidase activity from three species of microsporidia: Encephalitozoon cuniculi, Encephalitozoon hellem, and Vittaforma corneae
J. Parasitol.
88
843-848
2002
Encephalitozoon cuniculi, Encephalitozoon hellem
Manually annotated by BRENDA team
Hammer, G.E.; Gonzalez, F.; Champsaur, M.; Cado, D.; Shastri, N.
The aminopeptidase ERAAP shapes the peptide repertoire displayed by major histocompatibility complex class I molecules
Nat. Immunol.
7
103-112
2006
Mus musculus
Manually annotated by BRENDA team
Chang, S.C.; Momburg, F.; Bhutani, N.; Goldberg, A.L.
The ER aminopeptidase, ERAP1, trims precursors to lengths of MHC class I peptides by a molecular ruler mechanism
Proc. Natl. Acad. Sci. USA
102
17107-17112
2005
Sus scrofa
Manually annotated by BRENDA team
York, I.A.; Brehm, M.A.; Zendzian, S.; Towne, C.F.; Rock, K.L.
Endoplasmic reticulum aminopeptidase 1 (ERAP1) trims MHC class I-presented peptides in vivo and plays an important role in immunodominance
Proc. Natl. Acad. Sci. USA
103
9202-9207
2006
Mus musculus
Manually annotated by BRENDA team
Adachi, W.; Suzuki, N.N.; Fujioka, Y.; Suzuki, K.; Ohsumi, Y.; Inagaki, F.
Crystallization of Saccharomyces cerevisiae aminopeptidase 1, the major cargo protein of the Cvt pathway
Acta Crystallogr. Sect. F
63
200-203
2007
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Tishinov, K.; Nedkov, P.
Isolation and characterization of an aminopeptidase from sunflower seeds
C. R. Acad. Bulg. Sci.
60
1007-1010
2007
Helianthus annuus
-
Manually annotated by BRENDA team
Kostecka, Z.; Blahovec, J.; Kocisova, A.
Partial purification of larval aminopeptidases and determination of some kinetic parameters
Collect. Symp. Ser. Academy Sci. Czech Republic
9
66-68
2007
Musca domestica
-
Manually annotated by BRENDA team
Cortes, L.; Carvalho, A.L.; Todo-Bom, A.; Faro, C.; Pires, E.; Verissimo, P.
Purification of a novel aminopeptidase from the pollen of Parietaria judaica that alters epithelial integrity and degrades neuropeptides
J. Allergy Clin. Immunol.
118
878-884
2006
Parietaria judaica
Manually annotated by BRENDA team
Chen, S.; Marino, T.; Fang, W.; Russo, N.; Himo, F.
Peptide hydrolysis by the binuclear zinc enzyme aminopeptidase from Aeromonas proteolytica: A density functional theory study
J. Phys. Chem. B
112
2494-2500
2008
Vibrio proteolyticus
Manually annotated by BRENDA team
Schu, P.
Aminopeptidase I enzymatic activity
Methods Enzymol.
451
67-78
2008
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Evnouchidou, I.; Berardi, M.J.; Stratikos, E.
A continuous fluorigenic assay for the measurement of the activity of endoplasmic reticulum aminopeptidase 1: competition kinetics as a tool for enzyme specificity investigation
Anal. Biochem.
395
33-40
2009
Homo sapiens
Manually annotated by BRENDA team
Tsui, F.W.; Haroon, N.; Reveille, J.D.; Rahman, P.; Chiu, B.; Tsui, H.W.; Inman, R.D.
Association of an ERAP1 ERAP2 haplotype with familial ankylosing spondylitis
Ann. Rheum. Dis.
69
733-736
2010
Homo sapiens
Manually annotated by BRENDA team
Maksymowych, W.P.; Inman, R.D.; Gladman, D.D.; Reeve, J.P.; Pope, A.; Rahman, P.
Association of a specific ERAP1/ARTS1 haplotype with disease susceptibility in ankylosing spondylitis
Arthritis Rheum.
60
1317-1323
2009
Homo sapiens
Manually annotated by BRENDA team
Adamis, P.; Mannarino, S.; Riger, C.; Duarte, G.; Cruz, A.; Pereira, M.; Eleutherio, E.
Lap4, a vacuolar aminopeptidase I, is involved in cadmium-glutathione metabolism
Biometals
22
243-249
2009
Saccharomyces cerevisiae, Saccharomyces cerevisiae BY4741
Manually annotated by BRENDA team
Evnouchidou, I.; Papakyriakou, A.; Stratikos, E.
A new role for Zn(II) aminopeptidases: antigenic peptide generation and destruction
Curr. Pharm. Des.
15
3656-3670
2009
Mus musculus
Manually annotated by BRENDA team
Johnson, M.P.; Roten, L.T.; Dyer, T.D.; East, C.E.; Forsmo, S.; Blangero, J.; Brennecke, S.P.; Austgulen, R.; Moses, E.K.
The ERAP2 gene is associated with preeclampsia in Australian and Norwegian populations
Hum. Genet.
126
655-666
2009
Homo sapiens
Manually annotated by BRENDA team
Goto, Y.; Ogawa, K.; Hattori, A.; Tsujimoto, M.
Secretion of endoplasmic reticulum aminopeptidase 1 is involved in the activation of macrophages induced by lipopolysaccharide and interferon-gamma
J. Biol. Chem.
286
21906-21914
2011
Mus musculus
Manually annotated by BRENDA team
Kim, S.; Lee, S.; Shin, J.; Kim, Y.; Evnouchidou, I.; Kim, D.; Kim, Y.K.; Kim, Y.E.; Ahn, J.H.; Riddell, S.R.; Stratikos, E.; Kim, V.N.; Ahn, K.
Human cytomegalovirus microRNA miR-US4-1 inhibits CD8(+) T cell responses by targeting the aminopeptidase ERAP1
Nat. Immunol.
12
984-991
2011
Homo sapiens
Manually annotated by BRENDA team
Kochan, G.; Krojer, T.; Harvey, D.; Fischer, R.; Chen, L.; Vollmar, M.; von Delft, F.; Kavanagh, K.L.; Brown, M.A.; Bowness, P.; Wordsworth, P.; Kessler, B.M.; Oppermann, U.
Crystal structures of the endoplasmic reticulum aminopeptidase-1 (ERAP1) reveal the molecular basis for N-terminal peptide trimming
Proc. Natl. Acad. Sci. USA
108
7745-7750
2011
Homo sapiens
Manually annotated by BRENDA team
Chen, L.; Fischer, R.; Peng, Y.; Reeves, E.; McHugh, K.; Ternette, N.; Hanke, T.; Dong, T.; Elliott, T.; Shastri, N.; Kollnberger, S.; James, E.; Kessler, B.; Bowness, P.
Critical role of endoplasmic reticulum aminopeptidase 1 in determining the length and sequence of peptides bound and presented by HLA-B27
Arthritis Rheum.
66
284-294
2014
Homo sapiens (Q9NZ08)
Manually annotated by BRENDA team
Goto, Y.; Ogawa, K.; Nakamura, T.J.; Hattori, A.; Tsujimoto, M.
Substrate-dependent nitric oxide synthesis by secreted endoplasmic reticulum aminopeptidase 1 in macrophages
J. Biochem.
157
439-449
2015
Mus musculus, Mus musculus (Q9EQH2)
Manually annotated by BRENDA team
Aldhamen, Y.; Pepelyayeva, Y.; Rastall, D.; Seregin, S.; Zervoudi, E.; Koumantou, D.; Aylsworth, C.; Quiroga, D.; Godbehere, S.; Georgiadis, D.; Stratikos, E.; Amalfitano, A.
Autoimmune disease-associated variants of extracellular endoplasmic reticulum aminopeptidase 1 induce altered innate immune responses by human immune cells
J. Innate Immun.
7
275-289
2015
Homo sapiens, Homo sapiens (Q9NZ08)
Manually annotated by BRENDA team
Aldhamen, Y.A.; Seregin, S.S.; Rastall, D.P.; Aylsworth, C.F.; Pepelyayeva, Y.; Busuito, C.J.; Godbehere-Roosa, S.; Kim, S.; Amalfitano, A.
Endoplasmic reticulum aminopeptidase-1 functions regulate key aspects of the innate immune response
PLoS ONE
8
e69539
2013
Mus musculus (Q9EQH2)
Manually annotated by BRENDA team