Any feedback?
Please rate this page
(enzyme.php)
(0/150)

BRENDA support

Disease on EC 3.4.11.14 - cytosol alanyl aminopeptidase

Please use the Disease Search for a specific query.
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Adenomatous Polyposis Coli
Identification of differentially expressed genes in human pineal parenchymal tumors by microarray analysis.
Amyotrophic Lateral Sclerosis
Cu, Zn-superoxide dismutase 1 (SOD1) is a novel target of Puromycin-sensitive aminopeptidase (PSA/NPEPPS): PSA/NPEPPS is a possible modifier of amyotrophic lateral sclerosis.
Breast Neoplasms
Dictyostelium nucleomorphin is a member of the BRCT-domain family of cell cycle checkpoint proteins.
Cataract
Peptidases play an important role in cataractogenesis: an immunohistochemical study on lenses derived from Shumiya cataract rats.
cytosol alanyl aminopeptidase deficiency
Male reproductive defects caused by puromycin-sensitive aminopeptidase deficiency in mice.
Frontotemporal Dementia
Involvement of puromycin-sensitive aminopeptidase in proteolysis of tau protein in cultured cells, and attenuated proteolysis of frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17) mutant tau.
Infections
Identification and characterization of microRNA in the lung tissue of pigs with different susceptibilities to PCV2 infection.
Infertility, Female
Puromycin-sensitive aminopeptidase is essential for the maternal recognition of pregnancy in mice.
Neoplasms
Altered Activity and Expression of Cytosolic Peptidases in Colorectal Cancer.
Altered levels of acid, basic, and neutral peptidase activity and expression in human clear cell renal cell carcinoma.
Positioning of aminopeptidase inhibitors in next generation cancer therapy.
Neuroblastoma
cDNA cloning and molecular characterization of human brain metalloprotease MP100: a beta-secretase candidate?
Puromycin-sensitive aminopeptidase (PSA/NPEPPS) impedes development of neuropathology in hPSA/TAUP301L double-transgenic mice.
Neurodegenerative Diseases
Brain-Specific Aminopeptidase: From Enkephalinase to Protector Against Neurodegeneration.
Pancreatic Neoplasms
Autophagy creates a CTL epitope that mimics tumor-associated antigens.
Identification of a Ubiquitination-Related Gene Risk Model for Predicting Survival in Patients With Pancreatic Cancer.
Parkinsonian Disorders
Involvement of puromycin-sensitive aminopeptidase in proteolysis of tau protein in cultured cells, and attenuated proteolysis of frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17) mutant tau.
Stroke
Hemodynamic effects of epinephrine in rats: evaluation by impedance cardiography.
The effects of whole body vibration combined computerized postural control training on the lower extremity muscle activity and cerebral cortex activity in stroke patients.
Tauopathies
A genomic screen for modifiers of tauopathy identifies puromycin-sensitive aminopeptidase as an inhibitor of tau-induced neurodegeneration.
Uremia
Enzyme cytochemistry of rat organs after uremia with special reference to proteases.
Virus Diseases
Puromycin-sensitive aminopeptidase limits MHC class I presentation in dendritic cells but does not affect CD8 T cell responses during viral infections.