Disease on EC 3.3.2.9 - microsomal epoxide hydrolase
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abc-type xenobiotic transporter deficiency
Effect of ABCC2 (MRP2) Transport Function on Erythromycin Metabolism.
Aberrant Crypt Foci
Role of Hepatic and Intestinal P450 Enzymes in the Metabolic Activation of the Colon Carcinogen Azoxymethane in Mice.
Aberrant Crypt Foci
[Effects of astragalosides on induction of colorectal aberrant crypt foci by dimethylhydrazine and metabolizing enzymes in liver microsomes in rats]
Abetalipoproteinemia
17?-Estradiol-Induced Conformational Changes of Human Microsomal Triglyceride Transfer Protein: A Computational Molecular Modelling Study.
Abetalipoproteinemia
A 30-amino acid truncation of the microsomal triglyceride transfer protein large subunit disrupts its interaction with protein disulfide-isomerase and causes abetalipoproteinemia.
Abetalipoproteinemia
A distal effect of microsomal triglyceride transfer protein deficiency on the lysosomal recycling of CD1d.
Abetalipoproteinemia
A novel abetalipoproteinemia genotype. Identification of a missense mutation in the 97-kDa subunit of the microsomal triglyceride transfer protein that prevents complex formation with protein disulfide isomerase.
Abetalipoproteinemia
A severe form of abetalipoproteinemia caused by new splicing mutations of microsomal triglyceride transfer protein.
Abetalipoproteinemia
Abetalipoproteinemia caused by maternal isodisomy of chromosome 4q containing an intron 9 splice acceptor mutation in the microsomal triglyceride transfer protein gene.
Abetalipoproteinemia
Abetalipoproteinemia Due to a Novel Splicing Variant in MTTP in 3 Siblings.
Abetalipoproteinemia
Abetalipoproteinemia is caused by defects of the gene encoding the 97 kDa subunit of a microsomal triglyceride transfer protein.
Abetalipoproteinemia
Absence of microsomal triglyceride transfer protein in individuals with abetalipoproteinemia.
Abetalipoproteinemia
Adenovirus-mediated overexpression of microsomal triglyceride transfer protein (MTP): mechanistic studies on the role of MTP in apolipoprotein B-100 biogenesis.
Abetalipoproteinemia
An MTP inhibitor that normalizes atherogenic lipoprotein levels in WHHL rabbits.
Abetalipoproteinemia
An Unusual Presentation of Hemorrhagic Disease in an Infant: A Probable Case of Abetalipoproteinemia.
Abetalipoproteinemia
Analysis of the role of microsomal triglyceride transfer protein in the liver of tissue-specific knockout mice.
Abetalipoproteinemia
Apolipoprotein B48 glycosylation in abetalipoproteinemia and Anderson's disease.
Abetalipoproteinemia
Chronic adrenal failure and hypergonadotropic hypogonadism in a patient with abetalipoproteinemia.
Abetalipoproteinemia
Contemporary aspects of the biology and therapeutic regulation of the microsomal triglyceride transfer protein.
Abetalipoproteinemia
Hypobetalipoproteinemia and abetalipoproteinemia: liver disease and cardiovascular disease.
Abetalipoproteinemia
Hypobetalipoproteinemia with an apparently recessive inheritance due to a "de novo" mutation of apolipoprotein B.
Abetalipoproteinemia
Identification of two classes of lipid molecule binding sites on the microsomal triglyceride transfer protein.
Abetalipoproteinemia
Identification of two novel mutations and long-term follow-up in abetalipoproteinemia: a report of four cases.
Abetalipoproteinemia
Impaired Chylomicron Assembly Modifies Hepatic Metabolism Through Bile Acid-Dependent and Transmissible Microbial Adaptations.
Abetalipoproteinemia
Insights from human congenital disorders of intestinal lipid metabolism.
Abetalipoproteinemia
Knockout of the abetalipoproteinemia gene in mice: reduced lipoprotein secretion in heterozygotes and embryonic lethality in homozygotes.
Abetalipoproteinemia
Lack of MTTP Activity in Pluripotent Stem Cell-Derived Hepatocytes and Cardiomyocytes Abolishes apoB Secretion and Increases Cell Stress.
Abetalipoproteinemia
Loss of both phospholipid and triglyceride transfer activities of microsomal triglyceride transfer protein in abetalipoproteinemia.
Abetalipoproteinemia
Microsomal triglyceride transfer protein (MTP) gene mutations in Canadian subjects with abetalipoproteinemia.
Abetalipoproteinemia
Microsomal triglyceride transfer protein, the abetalipoproteinemia gene product, mediates the secretion of apolipoprotein B-containing lipoproteins from heterologous cells.
Abetalipoproteinemia
Molecular and functional analysis of two new MTTP gene mutations in an atypical case of abetalipoproteinemia.
Abetalipoproteinemia
Mutations of the microsomal triglyceride-transfer-protein gene in abetalipoproteinemia.
Abetalipoproteinemia
Novel Abetalipoproteinemia Missense Mutation Highlights the Importance of the N-Terminal ?-Barrel in Microsomal Triglyceride Transfer Protein Function.
Abetalipoproteinemia
Novel mutations in microsomal triglyceride transfer protein including maternal uniparental disomy in two patients with abetalipoproteinemia.
Abetalipoproteinemia
Novel mutations in the microsomal triglyceride transfer protein gene causing abetalipoproteinemia.
Abetalipoproteinemia
Primary deficiency of microsomal triglyceride transfer protein in human abetalipoproteinemia is associated with loss of CD1 function.
Abetalipoproteinemia
Structure-function analyses of microsomal triglyceride transfer protein missense mutations in abetalipoproteinemia and hypobetalipoproteinemia subjects.
Abetalipoproteinemia
The role of the microsomal triglygeride transfer protein in abetalipoproteinemia.
Abetalipoproteinemia
Using genetically engineered mice to understand apolipoprotein-B deficiency syndromes in humans.
Abetalipoproteinemia
[An adult case of probable Bassen-Kornzweig syndrome, presenting resting tremor]
Abnormalities, Multiple
Male pseudohermaphroditism due to multiple defects in steroid-biosynthetic microsomal mixed-function oxidases. A new variant of congenital adrenal hyperplasia.
Abortion, Spontaneous
Analysis of the EPHX1 113 polymorphism and GSTM1 homozygous null polymorphism and oral clefting associated with maternal smoking.
Abortion, Spontaneous
Effects of autoantibodies on the course of pregnancy and fetal growth.
Abortion, Spontaneous
Microsomal epoxide hydrolase polymorphism and risk of spontaneous abortion.
Abruptio Placentae
Low-activity haplotype of the microsomal epoxide hydrolase gene is protective against placental abruption.
Acidosis
Lysophosphatidylcholine metabolism in the rabbit heart. Characterization of metabolic pathways and partial purification of myocardial lysophospholipase-transacylase.
Acidosis
Regulation of lysophosphatidylcholine-metabolizing enzymes in isolated myocardial cells from rat heart.
Acne Vulgaris
13-cis-retinoic acid stimulates in vitro mannose 6-phosphate hydrolysis and inhibits retinol esterification and benzo[a]pyrene hydroxylation by rat-liver microsomes.
Acute Kidney Injury
Effects of acute renal failure induced by uranyl nitrate on the pharmacokinetics of intravenous theophylline in rats: the role of CYP2E1 induction in 1,3-dimethyluric acid formation.
Acute Kidney Injury
Pharmacokinetic changes of drugs in rat model of acute renal failure induced by uranyl nitrate: correlation between drug metabolism and hepatic microsomal cytochrome P450 isozymes.
Acute Kidney Injury
[Changes in hepatic microsomal cytochrome P-450 in glycerol rechallenged acute renal failure rats]
Acute Kidney Injury
[Effects of the calcium-channel blocker diltiazem on gentamicin-induced nephrotoxicity in rats]
Addison Disease
[Diabetes mellitus type I, thyroid gland autoimmunity, thyroid gland function and HLA status]
Addison Disease
[Tubercular Addison's disease with high titers of microsomal thyroid antibodies and reduced thyroid function reserve]
Adenocarcinoma
Acyl specificity in triacylglycerol synthesis by mammary adenocarcinoma R3230AC in Fischer rats.
Adenocarcinoma
Associations between genetic polymorphisms of Phase I and II metabolizing enzymes, p53 and susceptibility to esophageal adenocarcinoma.
Adenocarcinoma
EPHX1 polymorphisms do not modify esophageal carcinoma susceptibility in Dutch Caucasians.
Adenocarcinoma
Expression of microsomal prostaglandin E synthase-1 in intestinal type gastric adenocarcinoma and in gastric cancer cell lines.
Adenocarcinoma
Genetic polymorphisms of microsomal epoxide hydroxylase and glutathione S-transferases M1, T1 and P1, interactions with smoking, and risk for esophageal (Barrett) adenocarcinoma.
Adenocarcinoma
Polymorphisms in metabolic genes related to tobacco smoke and the risk of gastric cancer in the European prospective investigation into cancer and nutrition.
Adenocarcinoma
Reduced expression of the low affinity nerve growth factor receptor in benign and malignant human prostate tissue and loss of expression in four human metastatic prostate tumor cell lines.
Adenocarcinoma
The interaction between microsomal epoxide hydrolase polymorphisms and cumulative cigarette smoking in different histological subtypes of lung cancer.
Adenocarcinoma of Lung
Knockdown of microsomal glutathione S-transferase 1 inhibits lung adenocarcinoma cell proliferation and induces apoptosis.
Adenoma
A case-control study of microsomal epoxide hydrolase, smoking, meat consumption, glutathione S-transferase M3, and risk of colorectal adenomas.
Adenoma
A simple semiquantitative radiometric measurement of antithyroglobulin antibodies in human serum. Comparison with hemagglutination method.
Adenoma
Colorectal polyp type and the association with charred meat consumption, smoking, and microsomal epoxide hydrolase polymorphisms.
Adenoma
Epoxide hydrolase polymorphisms, cigarette smoking and risk of colorectal adenoma in the Nurses' Health Study and the Health Professionals Follow-up Study.
Adenoma
High expression of cytochrome b5 in adrenocortical adenomas from patients with Cushing's syndrome associated with high secretion of adrenal androgens.
Adenoma
In-vitro evidence for the regulation of 17,20-lyase activity by cytochrome b5 in adrenocortical adenomas from patients with Cushing's syndrome.
Adenoma
Levels of cytochrome P-450, steroidogenesis and microsomal and cytosolic epoxide hydrolases in normal human adrenal tissue and corresponding tumors.
Adenoma
Loss of microsomal antigen in follicular and papillary carcinoma of the thyroid. An immunofluorescence and electron-microscopic study.
Adenoma
Meat, vegetables and genetic polymorphisms and the risk of colorectal carcinomas and adenomas.
Adenoma
Microsomal epoxide hydrolase polymorphisms and risk for advanced colorectal adenoma.
Adenoma
Role of NQO1C609T and EPHX1 gene polymorphisms in the association of smoking and alcohol with sporadic distal colorectal adenomas: results from the UKFSS Study.
Adenoma
Steroid 21-hydroxylase and 17 alpha-hydroxylase in microsomal fraction of functioning adrenocortical tumors.
Adenoma
Subcellular site and mechanism of synthesis of disaturated phosphatidylcholine in alveolar type II cell adenomas.
Adenoma
System review and metaanalysis of the relationships between five metabolic gene polymorphisms and colorectal adenoma risk.
Adenoma
Transmembrane orientation of palmitoyl-CoA: lysophosphatidylcholine acyltransferase in microsomes isolated from an alveolar type II cell adenoma and rat liver.
Adenoma
Two-year carcinogenicity study in rats with a nonnucleoside reverse transcriptase inhibitor.
Adenoma
[Enzymohistochemical and immunomorphological study of experimental thyroid gland carcinoma]
Adenoma
[The concentration of nucleic acids in the subcellular structures of the thyroid gland in several of its diseases]
Adenoma, Islet Cell
Lipid composition of glucose-stimulated pancreatic islets and insulin-secreting tumor cells.
Adrenal Hyperplasia, Congenital
Characterisation of CAH alleles with non-radioactive DNA single strand conformation polymorphism analysis of the CYP21 gene.
Adrenal Hyperplasia, Congenital
Male pseudohermaphroditism due to multiple defects in steroid-biosynthetic microsomal mixed-function oxidases. A new variant of congenital adrenal hyperplasia.
Adrenal Insufficiency
Mechanism of adrenal insufficiency following trauma and severe hemorrhage: role of hepatic 11beta-hydroxysteroid dehydrogenase.
Adrenocortical Carcinoma
Hepatic microsomal enzyme induction and adrenal crisis due to o,p'DDD therapy for metastatic adrenocortical carcinoma.
Adrenocortical Carcinoma
Levels of cytochrome P-450, steroidogenesis and microsomal and cytosolic epoxide hydrolases in normal human adrenal tissue and corresponding tumors.
Adrenogenital Syndrome
Steroid 21-hydroxylase and 17 alpha-hydroxylase in microsomal fraction of functioning adrenocortical tumors.
Adrenoleukodystrophy
Enzymatic characterization of ELOVL1, a key enzyme in very long-chain fatty acid synthesis.
Agranulocytosis
Drug-protein conjugates--XIV. Mechanisms of formation of protein-arylating intermediates from amodiaquine, a myelotoxin and hepatotoxin in man.
Agranulocytosis
The cytotoxicity of clozapine metabolites: implications for predicting clozapine-induced agranulocytosis.
Alopecia Areata
Chronic active hepatitis associated with vitiligo, nail dystrophy, alopecia and a new variant of LKM antibodies.
Alzheimer Disease
Decreased prostaglandin synthesis in postmortem cerebral cortex from patients with Alzheimer's disease.
Alzheimer Disease
Expression of microsomal epoxide hydrolase is elevated in Alzheimer's hippocampus and induced by exogenous beta-amyloid and trimethyl-tin.
Alzheimer Disease
[Investigation of changes in fluidity of brain membranes in mice bearing experimental Alzheimer's disease using spin labeling electron paramagnetic resonance].
Alzheimer Disease
[The incidence of the thyroid microsomal autoantibodies in Alzheimer disease.]
Alzheimer Disease
[Trends in nonsteroidal anti-inflammatory drug development and application]
Amyotrophic Lateral Sclerosis
Concurrent blockade of free radical and microsomal prostaglandin E synthase-1-mediated PGE(2) production improves safety and efficacy in a mouse model of amyotrophic lateral sclerosis.
Anaphylaxis
The syndrome of thyroid autoimmunity and idiopathic chronic urticaria and angioedema presenting as anaphylaxis.
Anaphylaxis
[Effect of glycine on liver cytochrome P-450 and severity of experimental food anaphylaxis]
Anemia
13C-Methacetin metabolism in patients with cirrhosis: relation to disease severity, haemoglobin content and oxygen supply.
Anemia
Effects of oral contraceptive steroids (norethisterone/mestranol) on the activities of hepatic drug-metabolizing enzymes in iron-deficient anemic rats.
Anemia, Aplastic
Genetic polymorphisms of glutathione-S-transferase and microsomal epoxide hydrolase in egyptian acquired aplastic anemia patients.
Anemia, Aplastic
The clinical relevance and prognostic significance of microsomal epoxide hydrolase gene polymorphisms and their susceptibility to acquired aplastic anemia: an Egyptian study.
Anemia, Hemolytic
Human spleen heme oxygenase and microsomal electron transport system component activity in normals and in patients with hemolytic anemia, idiopathic thrombocytopenic purpura, and lymphoproliferative disorders.
Anemia, Pernicious
65-70 kD protein identified by immunoblotting as the presumptive gastric microsomal autoantigen in pernicious anaemia.
Anemia, Pernicious
Isolation of parietal cells from guinea-pig gastric mucosa and the immunological characterization of their antigenic structure.
Anemia, Pernicious
The 60- to 90-kDa parietal cell autoantigen associated with autoimmune gastritis is a beta subunit of the gastric H+/K(+)-ATPase (proton pump).
Anemia, Sickle Cell
Hepatic bilirubin UDP-glucuronyltransferase in patients with sickle cell anemia.
Anthracosis
[Gene variance in microsomal epoxide hydrolase and the susceptibility of coal workers' pneumoconiosis].
Antley-Bixler Syndrome Phenotype
P450 oxidoreductase deficiency: a new disorder of steroidogenesis affecting all microsomal P450 enzymes.
Aortic Aneurysm, Abdominal
Active smoking increases microsomal PGE2-synthase-1/PGE-receptor-4 axis in human abdominal aortic aneurysms.
Arbovirus Infections
[Behavior of microsomal mannosyl-transferases in cells carrying an arbovirus infection]
Arrhythmias, Cardiac
[Treatment of arrhythmia in patients with chronic ischemic heart disease using kinilentin combined with an inhibitor or inductor of microsomal oxidation]
Arthritis
Alteration of Hepatic microsomal enzyme systems and the lethal action of non-steroidal anti-arthritic drugs in acute and chronic models of inflammation.
Arthritis
Antithyroid-antibody activity in the snyovial fluid of patients with various arthritides.
Arthritis
Dietary lipid and iron status modulate lipid peroxidation in rats with induced adjuvant arthritis.
Arthritis
Glucuronidation of R- and S-ketoprofen, acetaminophen, and diflunisal by liver microsomes of adjuvant-induced arthritic rats.
Arthritis
The effect of adjuvant-induced arthritis on rat liver microsomal phospholipid metabolism.
Arthritis, Experimental
Drug metabolism under pathological and abnormal physiological states in animals and man.
Arthritis, Experimental
The effect of adjuvant-induced arthritis on rat liver microsomal phospholipid metabolism.
Arthritis, Experimental
[Adjuvant arthritis. Its effect on the level of 3-chloro-4-benzyloxyphenylacetic acid and on the activity of the liver microsomal system]
Arthritis, Experimental
[Influence of enzyme inducers and inhibitors of the metabolism of xenobiotics and of the coenzyme forms of vitamins B1 and B2 on the anti-inflammatory effect of voltaren]
Arthritis, Rheumatoid
A prospective evaluation of antithyroid antibody prevalence in 100 patients with rheumatoid arthritis.
Arthritis, Rheumatoid
Induction of microsomal prostaglandin E synthase in the rat brain endothelium and parenchyma in adjuvant-induced arthritis.
Arthritis, Rheumatoid
Microsomal prostaglandin E synthase is regulated by proinflammatory cytokines and glucocorticoids in primary rheumatoid synovial cells.
Arthritis, Rheumatoid
Prostaglandin E2 synthesizing enzymes in rheumatoid arthritis B cells and the effects of B cell depleting therapy on enzyme expression.
Arthritis, Rheumatoid
Prostaglandin synthetase activity from human rheumatoid synovial microsomes. Effect of 'aspirin-like' drug therapy.
Arthritis, Rheumatoid
Variants of gene for microsomal prostaglandin E2 synthase show association with disease and severe inflammation in rheumatoid arthritis.
Arthritis, Rheumatoid
[Thyroid autoantibodies in diabetes mellitus and rheumatoid arthritis]
arylsulfatase (type i) deficiency
Early diagnosis of recessive X-linked ichthyosis: elevation of cholesterol sulfate levels in placental sulfatase deficiency before the onset of skin symptoms.
arylsulfatase (type i) deficiency
[Microsomal sulfatase deficiency in X chromosome-linked ichthyosis]
Ascorbic Acid Deficiency
Ascorbic acid deficiency and induction of hepatic microsomal hydroxylative enzymes by organochlorine pesticides.
Ascorbic Acid Deficiency
Ascorbic acid deficiency decreases hepatic cytochrome P-450, especially CYP2B1/2B2, and simultaneously induces heme oxygenase-1 gene expression in scurvy-prone ODS rats.
Ascorbic Acid Deficiency
NADPH-dependent reduction of cytochrome P-450 in liver microsomes from vitamin C-deficient guinea pigs: effect of benzphetamine.
Ascorbic Acid Deficiency
The effect of ascorbic acid deficiency on extrahepatic microsomal metabolism of drugs and carcinogens in the guinea pig.
Ascorbic Acid Deficiency
The effect of certain vitamin deficiencies on hepatic drug metabolism.
Ascorbic Acid Deficiency
The effect of protein quality and ascorbic acid deficiency stimulation of hepatic microsomal enzymes in guinea pigs.
Asthma
Genetic variants in antioxidant genes are associated with diisocyanate-induced asthma.
Asthma
Genetic variation of genes for xenobiotic-metabolizing enzymes and risk of bronchial asthma: the importance of gene-gene and gene-environment interactions for disease susceptibility.
Asthma
IL10 polymorphisms are associated with airflow obstruction in severe alpha1-antitrypsin deficiency.
Asthma
Interactions between polycyclic aromatic hydrocarbons and epoxide hydrolase 1 play roles in asthma.
Asthma
Microsomal epoxide hydrolase, glutathione S-transferase P1, traffic and childhood asthma.
Asthma
Microsomal epoxide hydroxylase genotypes/diplotypes, traffic air pollution, and childhood asthma.
Asthma
Production of leukotriene C4 in different human tissues is attributable to distinct membrane bound biosynthetic enzymes.
Asthma
[The function of 2 detoxifying body systems in workers of the petrochemical industry]
Asthma, Aspirin-Induced
Aspirin-induced asthma. Hypersensitivity to fenoprofen and ibuprofen in relation to their inhibitory action on prostaglandin generation by different microsomal enzymic preparations.
Astrocytoma
Cytotoxicity of alkyl-lysophospholipid derivatives and low-alkyl-cleavage enzyme activities in rat brain tumor cells.
Astrocytoma
Microsomal membrane proteome of low grade diffuse astrocytomas: Differentially expressed proteins and candidate surveillance biomarkers.
Atherosclerosis
Competitive inhibition of hepatic sterol 27-hydroxylase by sitosterol: decreased activity in sitosterolemia.
Atherosclerosis
Decreased microsomal membrane fluidity in the development of cholesterol-induced atherosclerosis in the rabbit.
Atherosclerosis
Effect of reticulo-endothelial blockade and stimulation on hepatic mitochondrial and microsomal lipids and atherosclerosis in cholesterol-fed cockerels.
Atherosclerosis
Gene activation, apolipoprotein A-I/high density lipoprotein, atherosclerosis prevention and longevity.
Atherosclerosis
Implitapide, a microsomal triglyceride transfer protein inhibitor, reduces progression of atherosclerosis in apolipoprotein E knockout mice fed a Western-type diet: involvement of the inhibition of postprandial triglyceride elevation.
Atherosclerosis
Inhibitors of the Microsomal Prostaglandin E(2) Synthase-1 as Alternative to Non Steroidal Anti-inflammatory Drugs (NSAIDs) - A Critical Review.
Atherosclerosis
JTT-130, a novel intestine-specific inhibitor of microsomal triglyceride transfer protein, ameliorates lipid metabolism and attenuates atherosclerosis in hyperlipidemic animal models.
Atherosclerosis
MicroRNA-30c Mimic Mitigates Hypercholesterolemia and Atherosclerosis in Mice.
Atherosclerosis
Nonoxidative ethanol metabolism: formation of fatty acid ethyl esters by cholesterol esterase.
Atherosclerosis
Reversal of hyperlipidemia with a genetic switch favorably affects the content and inflammatory state of macrophages in atherosclerotic plaques.
Atherosclerosis
The lipid-lowering effects of lomitapide are unaffected by adjunctive apheresis in patients with homozygous familial hypercholesterolaemia - a post-hoc analysis of a Phase 3, single-arm, open-label trial.
Atherosclerosis
The possible role of Ca2+ on the activation of microsomal triglyceride transfer protein in rat hepatocytes.
Atherosclerosis
[Biosynthesis and excretion of cholesterol in mice of line SWR with hereditary atherosclerosis and effects of multifunctional microsomal oxidase inducer on these processes]
Atherosclerosis
[Change in the activity of the microsomal system of liver oxidation in rabbits in experimental atherosclerosis]
Atherosclerosis
[Effect of the early postnatal induction of microsomal enzymes on their activity and the cholesterol content in the blood of adult mice from a hypercholesteremic line]
Atherosclerosis
[Experimental myocardial infarction in atherosclerosis--various methods of pharmacological correction]
Atherosclerosis
[Lipid peroxides and atherosclerosis. Hypothesis: the role of cholesterol and free-radical lipid peroxidation in altering cell membrane properties in hypercholesterolemia and atherosclerosis]
Atherosclerosis
[Oxidation state of membrane phospholipids and activity of the microsomal system of cholesterol hydroxylation in the liver of animals during atherogenesis]
Autoimmune Diseases
Antibodies to liver/kidney microsome1 in chronic active hepatitis recognize specific forms of hepatic cytochrome P-450.
Autoimmune Diseases
Autoantibodies to the thyroid microsomal/thyroid peroxidase antigen are polyclonal and directed to several distinct antigenic sites.
Autoimmune Diseases
Expression of the microsomal antigen on the surface of continuously cultured rat thyroid cells is modulated by thyrotropin.
Autoimmune Diseases
Immunologic parameters in premature follicular depletion: T and B lymphocytes, T-cell subpopulations, cutaneous reactivity, and serum immunoglobulin concentrations.
Autoimmune Diseases
Incidence and significance of organ-specific autoimmune disorders (clinical, latent or only autoantibodies) in patients with vitiligo.
Autoimmune Diseases
Non-organ specific autoantibodies associated with chronic C virus hepatitis.
Autoimmune Diseases
Partially compensated hypoadrenalism presenting with persistent skin pigmentation.
Autoimmune Diseases
Postpartum activation of autoimmunity: transient increase of total IgG levels in normal women and in women with autoimmune thyroiditis.
Autoimmune Diseases
The effect of cyclosporine A on renal and hepatic microsomal mixed function oxidase systems in rats.
Autoimmune Diseases
The effect of sulphydryl reagents on the human thyroid microsomal antigen.
Autoimmune Diseases
[Chronic fatigue syndrome: immune dysfunction, role of pathogens and toxic agents and neurological and cardial changes]
Autoimmune Diseases
[Investigation of autoimmunity markers during interferon alpha therapy of chronic hepatitis B and C - twenty years of experience].
Autoimmune Diseases
[Thyroid microsomal autoantibodies in thyroid disease: their value as an antigenic marker]
Avitaminosis
Hepatic peroxisome proliferation in vitamin A-deficient mice without a simultaneous increase in peroxisomal acyl-CoA oxidase activity.
Avitaminosis
Vitamin B-12 deficiency increases the specific activities of rat liver NADH- and NADPH-linked aquacobalamin reductase isozymes involved in coenzyme synthesis.
Avitaminosis
[Activity of enzymes participating in xenobiotic metabolism and the condition of microsomal membranes of rat liver in vitamin K deficiency]
Behcet Syndrome
Gastric parietal cell and thyroid autoantibodies in patients with Behcet's disease.
Biliary Atresia
Microsomal protein per gram of liver (MPPGL) in paediatric biliary atresia patients.
Blister
Ischemic loss of sarcolemmal dystrophin and spectrin: correlation with myocardial injury.
Bone Diseases
Genetic polymorphisms of EPHX1, Gsk3beta, TNFSF8 and myeloma cell DKK-1 expression linked to bone disease in myeloma.
Bone Diseases, Metabolic
Antiopyrine half-life as a measure of hepatic enzyme induction: clinical applications in a chronic epileptic population.
Bowen's Disease
Aminopeptidase M and dipeptidyl peptidase IV activity in epithelial skin tumors: a histochemical study.
Brain Edema
Phospholipid pool, lipid peroxidation, and superoxide dismutase activity under various types of oxidative stress of the brain and the effect of low-energy infrared laser irradiation.
Brain Injuries
Missense Genetic Polymorphisms of Microsomal (EPHX1) and Soluble Epoxide Hydrolase (EPHX2) and Their Relation to the Risk of Large Artery Atherosclerotic Ischemic Stroke in a Turkish Population.
Brain Injuries
Protective Effects of Riboflavin and Selenium on Brain Microsomal Ca(2+)-ATPase and Oxidative Damage Caused by Glyceryl Trinitrate in a Rat Headache Model.
Brain Ischemia
[Membrane damage in brain subcellular structures in terminal states and in the postresuscitation period]
Brain Neoplasms
Development of monoclonal antibodies to human microsomal epoxide hydrolase and analysis of "preneoplastic antigen"-like molecules.
Brain Neoplasms
Identification of the putative brain tumor antigen BF7/GE2 as the (de)toxifying enzyme microsomal epoxide hydrolase.
Brain Neoplasms
Investigation of the Association between Genetic Polymorphism of Microsomal Epoxide Hydrolase and Primary Brain Tumor Incidence.
Brain Neoplasms
The chemopreventive properties of chlorogenic acid reveal a potential new role for the microsomal glucose-6-phosphate translocase in brain tumor progression.
Brain Neoplasms
Use of phenobarbital and high doses of 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea in the treatment of brain tumor-bearing mice.
Brain Neoplasms
Variation in genes relevant to aromatic hydrocarbon metabolism and the risk of adult brain tumors.
Brain Neoplasms
[ACNU delivery to malignant tumor tissue and serum--route of administration and combined use of phenobarbital]
Breast Neoplasms
17 beta-estradiol hydroxylation catalyzed by human cytochrome P450 1A1: a comparison of the activities induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin in MCF-7 cells with those from heterologous expression of the cDNA.
Breast Neoplasms
4-Hydroxylated metabolites of the antiestrogens tamoxifen and toremifene are metabolized to unusually stable quinone methides.
Breast Neoplasms
A systematic approach to analysing gene-gene interactions: polymorphisms at the microsomal epoxide hydrolase EPHX and glutathione S-transferase GSTM1, GSTT1, and GSTP1 loci and breast cancer risk.
Breast Neoplasms
Activation of brain estrogen receptors in mice lactating from mothers exposed to DDT.
Breast Neoplasms
Activation of the novel estrogen receptor G protein-coupled receptor 30 (GPR30) at the plasma membrane.
Breast Neoplasms
Antiestrogen binding sites in microsomal fractions of malignant and nonmalignant human breast tissues.
Breast Neoplasms
Characterization of estrogen and antiestrogen binding to the cytosol and microsomes of breast tumors.
Breast Neoplasms
Co-expression of human CYP1A1 and a human analog of cytochrome P450-EF in response to 2,3,7,8-tetrachloro-dibenzo-p-dioxin in the human mammary carcinoma-derived MCF-7 cells.
Breast Neoplasms
CYP3A4, CYP2C9 and CYP2B6 expression and ifosfamide turnover in breast cancer tissue microsomes.
Breast Neoplasms
Ethanol-induced oxidative stress and acetaldehyde formation in rat mammary tissue: potential factors involved in alcohol drinking promotion of breast cancer.
Breast Neoplasms
Expression and regulation of breast cancer resistance protein and multidrug resistance associated protein 2 in BALB/c mice.
Breast Neoplasms
Functional genomics based prioritization of potential nsSNPs in EPHX1, GSTT1, GSTM1 and GSTP1 genes for breast cancer susceptibility studies.
Breast Neoplasms
Identification and pharmacological characterization of cholesterol-5,6-epoxide hydrolase as a target for tamoxifen and AEBS ligands.
Breast Neoplasms
Immunochemical specificity of placental NADPH cytochrome c (P-450) reductase in neoplastic and non-neoplastic human tissue.
Breast Neoplasms
Implication of Xenobiotic Metabolizing Enzyme gene (CYP2E1, CYP2C19, CYP2D6, mEH and NAT2) polymorphisms in breast carcinoma.
Breast Neoplasms
Increased 3-hydroxy-3-methyl-glutaryl coenzyme A reductase activity in a virilizing adrenal carcinoma.
Breast Neoplasms
Interaction of gangliosides with the methyltransferase-I of microsomes from normal and neoplastic human mammary gland.
Breast Neoplasms
Ligands of the antiestrogen-binding site induce active cell death and autophagy in human breast cancer cells through the modulation of cholesterol metabolism.
Breast Neoplasms
Lipid-bound sugars in malignant human breast tumors. Partial characterization of mannosyl and glucosyl transferase activities.
Breast Neoplasms
Meta-analysis of microsomal epoxide hydrolase gene polymorphism and the risk of breast carcinoma.
Breast Neoplasms
Microsomal antiestrogen-binding site ligands induce growth control and differentiation of human breast cancer cells through the modulation of cholesterol metabolism.
Breast Neoplasms
Microsomal binding sites for antioestrogens in rat liver. Properties and detergent solubilization.
Breast Neoplasms
Microsomal binding sites for nonsteroidal anti-estrogens in MCF 7 human mammary carcinoma cells. Demonstration of high affinity and narrow specificity for basic ether derivatives of triphenylethylene.
Breast Neoplasms
Microsomal epoxide hydrolase expression as a predictor of tamoxifen response in primary breast cancer: a retrospective exploratory study with long-term follow-up.
Breast Neoplasms
Microsomal epoxide hydrolase expression in the endometrial uterine corpus is regulated by progesterone during the menstrual cycle.
Breast Neoplasms
Microsomal epoxide hydrolase variants are not associated with risk of breast cancer.
Breast Neoplasms
Proteolysis of human prolactin: resistance to cathepsin D and formation of a nonangiostatic, C-terminal 16K fragment by thrombin.
Breast Neoplasms
Quantitative assessment of the effects of the EPHX1 Tyr113His polymorphism on lung and breast cancer.
Breast Neoplasms
Rat breast microsomal biotransformation of ethanol to acetaldehyde but not to free radicals: its potential role in the association between alcohol drinking and breast tumor promotion.
Breast Neoplasms
Species differences in the covalent binding of [14C]tamoxifen to liver microsomes and the forms of cytochrome P450 involved.
Breast Neoplasms
Subcellular and extracellular localization of specific binding sites for triphenylethylene antiestrogens in human breast cancer.
Breast Neoplasms
Synthesis and reactivity of a potential carcinogenic metabolite of tamoxifen: 3,4-dihydroxytamoxifen-o-quinone.
Breast Neoplasms
The effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on estrogen metabolism in MCF-7 breast cancer cells: evidence for induction of a novel 17 beta-estradiol 4-hydroxylase.
Breast Neoplasms
Thyroid and other autoantibodies in British and Japanese women: an epidemiological study of breast cancer.
Breast Neoplasms
Time and dose-dependent modulation of phase 1 and phase 2 gene expression in response to treatment of MCF-7 cells with a natural anti-cancer agent.
Breast Neoplasms
Try113His and His139Arg polymorphisms in the microsomal epoxide hydrolase gene are not associated with risk of breast cancer.
Breast Neoplasms
[Biotransformation of phenazone and sulfadimidine as markers of liver metabolism of drug and xenobiotic oxidation and acetylation in women with breast cancer]
Breast Neoplasms
[Initial stages in the mechanism of protein glycosylation in human breast neoplasms]
Bronchitis
Air pollution and childhood bronchitis: Interaction with xenobiotic, immune regulatory and DNA repair genes.
Bronchitis
[Role of polymorphic variants of cytochrome P450 genes (CYP1A1, CYP2E1) and microsomal epoxide hydrolase (mEPHX) in pathogenesis of cystic fibrosis and chronic respiratory tract diseases]
Bronchitis, Chronic
Genetic polymorphisms in the cytochromes P-450 (1A1, 2E1), microsomal epoxide hydrolase and glutathione S-transferase M1, T1, and P1 genes, and their relationship with chronic bronchitis and relapsing pneumonia in children.
Bronchitis, Chronic
[The function of 2 detoxifying body systems in workers of the petrochemical industry]
Burkitt Lymphoma
Enhanced Ii expression after n-butyrate treatment of a P3HR-1 Burkitt's lymphoma subline which does not express HLA-D.
Burning Mouth Syndrome
Anemia, hematinic deficiencies, and hyperhomocysteinemia in serum gastric parietal cell antibody-positive burning mouth syndrome patients without serum thyroid autoantibodies.
Carcinogenesis
A microsomal butyrylesterase appearing in rat livers during development, regeneration, and carcinogenesis, and after phenobarbital treatment.
Carcinogenesis
Alteration of microsomal and mitochondrial sites of metabolic control during chemical carcinogenesis.
Carcinogenesis
Analysis of the EPHX1 113 polymorphism and GSTM1 homozygous null polymorphism and oral clefting associated with maternal smoking.
Carcinogenesis
Association of Environmental Arsenic Exposure, Genetic Polymorphisms of Susceptible Genes, and Skin Cancers in Taiwan.
Carcinogenesis
Capsaicin, a double-edged sword: toxicity, metabolism, and chemopreventive potential.
Carcinogenesis
Catecholestrogens as mediators of carcinogenesis: correlation of aromatic hydroxylation of estradiol and its fluorinated analogs with tumor induction in Syrian hamsters.
Carcinogenesis
Changes in carboxylesterase isoenzymes of rat liver microsomes during hepatocarcinogenesis.
Carcinogenesis
Combined effect of genetic polymorphisms in phase I and II biotransformation enzymes on head and neck cancer risk.
Carcinogenesis
Comparison of acyltransferase-mediated mutagenicity and nucleic acid binding of N-acetoxy-4-acetylaminobiphenyl by hepatic and bladder microsomes from rats and dogs.
Carcinogenesis
Covalent binding of the carcinogen trichloroethylene to hepatic microsomal proteins and to exogenous DNA in vitro.
Carcinogenesis
Curcumin blocks prostaglandin E2 biosynthesis through direct inhibition of the microsomal prostaglandin E2 synthase-1.
Carcinogenesis
Effect of chronic estrogen treatment of Syrian hamsters on microsomal enzymes mediating formation of catecholestrogens and their redox cycling: implications for carcinogenesis.
Carcinogenesis
Effect of cigarette smoke on mutagenic activation of environmental carcinogens by cytochrome P450 2A8 and inactivation by glucuronidation in hamster liver.
Carcinogenesis
Effects of palm carotenoids in rat hepatic cytochrome P450-mediated benzo(a)pyrene metabolism.
Carcinogenesis
Effects of selenium on 7,12-dimethylbenz(a)anthracene-induced mammary carcinogenesis and DNA adduct formation.
Carcinogenesis
Expression of rat microsomal epoxide hydrolase gene during liver chemical carcinogenesis.
Carcinogenesis
Genetic polymorphisms of smoking-related carcinogen detoxifying enzymes and head and neck cancer susceptibility.
Carcinogenesis
Hepatic drug metabolizing enzyme activity and tumorigenesis in mice following perinatal exposure to benzo(a)pyrene.
Carcinogenesis
Hepatic metabolism and carcinogenesis. Its role in hepatoma and adenocarcinoma.
Carcinogenesis
Hepatic microsomal N-glucuronidation and nucleic acid binding of N-hydroxy arylamines in relation to urinary bladder carcinogenesis.
Carcinogenesis
Heterocyclic polycyclic aromatic hydrocarbon carcinogenesis: 7H-dibenzo[c,g]carbazole metabolism by microsomal enzymes from mouse and rat liver.
Carcinogenesis
Heterogeneous nuclear ribonucleoproteins and their interactors are a major class of deregulated proteins in anaplastic astrocytoma: a grade III malignant glioma.
Carcinogenesis
Hyperforin, an Anti-Inflammatory Constituent from St. John's Wort, Inhibits Microsomal Prostaglandin E(2) Synthase-1 and Suppresses Prostaglandin E(2) Formation in vivo.
Carcinogenesis
Identification of 5-lipoxygenase and microsomal prostaglandin E2 synthase-1 as functional targets of the anti-inflammatory and anti-carcinogenic garcinol.
Carcinogenesis
Immunofluorescence of NADPH-cytochrome c (P-450) reductase in rat and minipig tissues injected with phenobarbital.
Carcinogenesis
Immunofluorescence of phenobarbital inducible cytochrome P-450 in the hepatic lobule of normal and phenobarbital-treated rats.
Carcinogenesis
In vitro metabolism and covalent binding of ethylbenzene to microsomal protein as a possible mechanism of ethylbenzene-induced mouse lung tumorigenesis.
Carcinogenesis
In vitro screening of carcinogenesis inhibitors acting by inhibition of microsomal polycyclic aromatic hydrocarbon activation.
Carcinogenesis
Inducibility of microsomal enzymes in normal and pre-cancerous lung tissue. Synergistic action of 5-6 benzoflavon or methyl-cholanthrene in radiation induced carcinogenesis.
Carcinogenesis
Induction of microsomal enzymes by foreign chemicals and carcinogenesis by polycyclic aromatic hydrocarbons: G. H. A. Clowes Memorial Lecture.
Carcinogenesis
Induction of microsomal epoxide hydrolase by sulfur amino acid deprivation via the pathway of C-Jun N-terminal kinase and its extracellular exposure during cell death.
Carcinogenesis
Inhibition of microsomal metabolism and chemical oncogenesis in culture by naphthalene quinones.
Carcinogenesis
Inhibitors of the Microsomal Prostaglandin E(2) Synthase-1 as Alternative to Non Steroidal Anti-inflammatory Drugs (NSAIDs) - A Critical Review.
Carcinogenesis
Ketonitrosamines as metabolites of methyl-n-amylnitrosamine (MNAN) and its hydroxy derivatives in the rat.
Carcinogenesis
Lack of association of EPHX1 gene polymorphisms with risk of hepatocellular carcinoma: a meta-analysis.
Carcinogenesis
Localization of estrogen-induced DNA adducts and cytochrome P-450 activity at the site of renal carcinogenesis in the hamster kidney.
Carcinogenesis
Low microsomal epoxide hydrolase expression is associated with bladder carcinogenesis and recurrence.
Carcinogenesis
Mechanism of carcinogenesis with 1-aryl-3,3-dialkyltriazenes. Enzymatic dealkylation by rat liver microsomal fraction in vitro.
Carcinogenesis
Microsomal aryl hydrocarbon hydroxylases: on their role in polycyclic hydrocarbon carcinogenesis and toxicity and the mechanism of enzyme induction.
Carcinogenesis
Microsomal epoxide hydrolase genotypes and the risk for head and neck cancer.
Carcinogenesis
Microsomal epoxide hydrolase polymorphisms, cigarette smoking, and risk of colorectal cancer: The Fukuoka Colorectal Cancer Study.
Carcinogenesis
Microsomal hydroxylases: induction and role in polycyclic hydrocarbon carcinogenesis and toxicity.
Carcinogenesis
Microsomal hydroxylation of 2- and 4-fluoroestradiol to catechol metabolites and their conversion to methyl ethers: catechol estrogens as possible mediators of hormonal carcinogenesis.
Carcinogenesis
Microsomal membrane alterations during acute ethionine toxicity and carcinogenesis.
Carcinogenesis
Microsomal N-hydroxylase modification as a first step in carcinogenesis by arylamines [proceedings]
Carcinogenesis
Modifications of 3'-methyl-4-dimethylaminoazobenzene carcinogenesis of rat liver and carcinogen metabolism by portacaval anastomosis.
Carcinogenesis
Modifications of carcinogen metabolism in hepatic microsomes of suckling young by 3-methylcholanthrene or beta-naphthoflavone administered to lactating rats.
Carcinogenesis
Monooxygenase system in Guerins carcinoma of rats under conditions of ?-3 polyunsaturated fatty acids administration.
Carcinogenesis
Putative EPHX1 Enzyme Activity Is Related with Risk of Lung and Upper Aerodigestive Tract Cancers: A Comprehensive Meta-Analysis.
Carcinogenesis
Role of NQO1C609T and EPHX1 gene polymorphisms in the association of smoking and alcohol with sporadic distal colorectal adenomas: results from the UKFSS Study.
Carcinogenesis
Some biochemical properties of the preneoplastic antigen in rat liver hyperplastic nodules.
Carcinogenesis
Species susceptibility to aflatoxin B1 carcinogenesis: comparative kinetics of microsomal biotransformation.
Carcinogenesis
Stereochemistry of the major rodent liver microsomal metabolites of thecarcinogen dibenz[a,j]acridine.
Carcinogenesis
Structure-activity relationships in polycyclic aromatic hydrocarbons: induction of microsomal aryl hydrocarbon hydroxylase and its possible importance in chemical carcinogenesis.
Carcinogenesis
Studies on azo-dye carcinogenesis in rat liver. The effect of 4-dimethylamino-3'-methylazobenzene on the incorporation of [C]leucine into rat-liver microsomal protein.
Carcinogenesis
Superoxide dismutase depletion and lipid peroxidation in rat liver microsomal membranes: correlation with liver carcinogenesis.
Carcinogenesis
Suppressive effects of dietary curcumin on the increased activity of renal ornithine decarboxylase in mice treated with a renal carcinogen, ferric nitrilotriacetate.
Carcinogenesis
Targeted disruption of the microsomal epoxide hydrolase gene. Microsomal epoxide hydrolase is required for the carcinogenic activity of 7,12-dimethylbenz[a]anthracene.
Carcinogenesis
Targeted over-expression of mPGES-1 and elevated PGE2 production is not sufficient for lung tumorigenesis in mice.
Carcinogenesis
The effect of modifiers of microsomal enzymes on chemical oncogenesis in cultures of C3H mouse cell lines.
Carcinogenesis
The levels of quinone reductases, superoxide dismutase and glutathione-related enzymatic activities in diethylstilbestrol-induced carcinogenesis in the kidney of male Syrian golden hamsters.
Carcinogenesis
The use of gene knockout mice to unravel the mechanisms of toxicity and chemical carcinogenesis.
Carcinogenesis
Weighted gene co-expression network analysis of pneumocytes under exposure to a carcinogenic dose of chloroprene.
Carcinogenesis
[A study on the inherited susceptibility of chromosomal damage in peripheral blood lymphocytes among coke oven workers]
Carcinogenesis
[Activity of 2 microsomal enzymes during the initial stage of liver carcinogenesis induced by 4-dimethylaminoazobenzene.]
Carcinogenesis
[Disorders in the regulation of the activity of microsomal enzymes by lipids during chemical carcinogenesis in the liver]
Carcinogenesis
[Effect of low doses of x-ray irradiation on the liver detoxication system in rats with transplanted Guerin's carcinoma].
Carcinogenesis
[Functional activity of NADH-dependent reductase system in the liver microsomal fraction and Guerin's carcinoma in rats exposed to preliminary irradiation].
Carcinogenesis
[Functional analysis of drug metabolizing enzymes using gene knockout animals]
Carcinogenesis
[The interaction between microsomal epoxide hydrolase polymorphisms and indoor pollution in non small cell lung cancer]
Carcinogenesis
[The relationship between the activity of microsomal enzymes and pulmonary carcinogenesis in mice]
Carcinoma
A simple semiquantitative radiometric measurement of antithyroglobulin antibodies in human serum. Comparison with hemagglutination method.
Carcinoma
Aminopeptidase M and dipeptidyl peptidase IV activity in epithelial skin tumors: a histochemical study.
Carcinoma
Association of Activity Altering Genotypes - Tyr113His and His139Arg in Microsomal Epoxide Hydrolase Enzyme with Esophageal Squamous Cell Carcinoma.
Carcinoma
Association of cell surface antigens with microsomal membrane fractions derived from Ehrlich ascites carcinoma cells.
Carcinoma
Association of CYP1A1 and microsomal epoxide hydrolase polymorphisms with lung squamous cell carcinoma.
Carcinoma
Case-control study of oral and oropharyngeal cancer in whites and genetic variation in eight metabolic enzymes.
Carcinoma
Characterization of 3-hydroxy-3-methylglutaryl coenzyme A reductase in human adrenal cortex.
Carcinoma
Co-expression of human CYP1A1 and a human analog of cytochrome P450-EF in response to 2,3,7,8-tetrachloro-dibenzo-p-dioxin in the human mammary carcinoma-derived MCF-7 cells.
Carcinoma
Curcumin blocks prostaglandin E2 biosynthesis through direct inhibition of the microsomal prostaglandin E2 synthase-1.
Carcinoma
CYP1A1, GSTs and mEH polymorphisms and susceptibility to esophageal carcinoma: study of population from a high- incidence area in north China.
Carcinoma
EPHX1 polymorphisms do not modify esophageal carcinoma susceptibility in Dutch Caucasians.
Carcinoma
Epoxide hydrolase Tyr113His polymorphism is not associated with susceptibility to esophageal squamous cell carcinoma in population of North China.
Carcinoma
Expression of cyclooxygenase-2 and microsomal prostagalandin E synthase-1 in head and neck squamous cell carcinoma.
Carcinoma
Formation of 5,16-androstadien-3 beta-ol from pregnenolone in human testicular microsomes.
Carcinoma
Identification of Enzymes Oxidizing the Tyrosine Kinase Inhibitor Cabozantinib: Cabozantinib Is Predominantly Oxidized by CYP3A4 and Its Oxidation Is Stimulated by cyt b5 Activity.
Carcinoma
Identification of protein disulfide isomerase and calreticulin as autoimmune antigens in LEC strain of rats.
Carcinoma
In vitro effect of 16alpha-hydroxyprogesterone on the enzyme activities related to androgen production in human testes.
Carcinoma
Increased 3-hydroxy-3-methyl-glutaryl coenzyme A reductase activity in a virilizing adrenal carcinoma.
Carcinoma
Inhibition of human gastric carcinoma cell growth by treatment of N(3)-o-toluyl-fluorouracil as a precursor of 5-fluorouracil.
Carcinoma
Interaction of human macrophage C-type lectin with O-linked N-acetylgalactosamine residues on mucin glycopeptides.
Carcinoma
Levels of cytochrome P-450, steroidogenesis and microsomal and cytosolic epoxide hydrolases in normal human adrenal tissue and corresponding tumors.
Carcinoma
Loss of microsomal antigen in follicular and papillary carcinoma of the thyroid. An immunofluorescence and electron-microscopic study.
Carcinoma
Low microsomal epoxide hydrolase expression is associated with bladder carcinogenesis and recurrence.
Carcinoma
Meat, vegetables and genetic polymorphisms and the risk of colorectal carcinomas and adenomas.
Carcinoma
Metabolism of linoleic and arachidonic acids in VX2 carcinoma tissue: identification of monohydroxy octadecadienoic acids and monohydroxy eicosatetraenoic acids.
Carcinoma
Microsomal binding sites for nonsteroidal anti-estrogens in MCF 7 human mammary carcinoma cells. Demonstration of high affinity and narrow specificity for basic ether derivatives of triphenylethylene.
Carcinoma
Microsomal enzymes in patients with gastric carcinoma as determined by plasma half-life of antipyrine.
Carcinoma
Microsomal epoxide hydrolase and glutathione S-transferase polymorphisms in relation to laryngeal carcinoma risk.
Carcinoma
Microsomal fatty acid desaturation and elongation in a human lung carcinoma grown in nude mice.
Carcinoma
Mitochondrial and microsomal peripheral benzodiazepine receptors in human ovarian cancer xenografts.
Carcinoma
Molecular basis of basal cell carcinoma: analysis of differential gene expression by differential display PCR and expression array.
Carcinoma
Monoclonal antibody to a proximal nephrogenic renal antigen: immunohistochemical analysis of formalin-fixed, paraffin-embedded human renal cell carcinomas.
Carcinoma
Monooxygenase system in Guerins carcinoma of rats under conditions of ?-3 polyunsaturated fatty acids administration.
Carcinoma
Monooxygenase, epoxide hydrolase, and glutathione-S-transferase activities in human lung. Variation between groups of bronchogenic carcinoma and non-cancer patients and interindividual differences.
Carcinoma
Occurrence of autoimmune antibodies to liver microsomal proteins in association with fulminant hepatitis in the LEC strain of rats.
Carcinoma
Polymorphisms in metabolizing enzymes and the risk of head and neck squamous cell carcinoma in the Slavic population of the central Europe.
Carcinoma
Reduction of nitromin to nitrogen mustard: unscheduled DNA synthesis in aerobic or anaerobic rat hepatocytes, JB1, BL8 and Walker carcinoma cell lines.
Carcinoma
Reductive metabolism of 3-amino-1,2,4-benzotriazine-1,4-dioxide (SR 4233) and the induction of unscheduled DNA synthesis in rat and human derived cell lines.
Carcinoma
STUDIES ON THE SURFACE AND CYTOPLASMIC MEMBRANES OF EHRLICH ASCITES CARCINOMA CELLS. II. ALKALI-CATION-ACTIVATED ADENOSINE TRIPHOSPHATE HYDROLYSIS IN A MICROSOMAL MEMBRANE FRACTION.
Carcinoma
The effect of inhibition of Ca2+-independent phospholipase A2 on chemotherapeutic-induced death and phospholipid profiles in renal cells.
Carcinoma
The high-affinity binding of [3H]norharman ([3H]beta-carboline) to the ethanol-inducible cytochrome P450 2E1 in rat liver.
Carcinoma
The interaction between microsomal epoxide hydrolase polymorphisms and cumulative cigarette smoking in different histological subtypes of lung cancer.
Carcinoma
Two-year carcinogenicity study in rats with a nonnucleoside reverse transcriptase inhibitor.
Carcinoma
[Effect of liposomal antitumor preparation 5,6-benzocoumarin-5-uracil on intensity of free-radical processes in the liver microsomes and tumor cells of rats with transplanted Guerin's carcinoma]
Carcinoma
[Effect of liposomal antitumor preparation 5-(5',6'-benzocoumarin-3')-methylaminouracil hydrobromide on cytochrome P-450 in the microsomal liver fraction of tumor bearing rats]
Carcinoma
[Functional activity of NADH-dependent reductase system in the liver microsomal fraction and Guerin's carcinoma in rats exposed to preliminary irradiation].
Carcinoma
[The induction of Guerin's carcinoma cytochrome p450 hydroxylase activity by retinoids].
Carcinoma
[Transketolase activity and the TDP effect in tissues of animals with experimental tumors]
Carcinoma, Basal Cell
Aminopeptidase M and dipeptidyl peptidase IV activity in epithelial skin tumors: a histochemical study.
Carcinoma, Ehrlich Tumor
Altered distribution of constitutive forms of microsomal cytochrome P-450 in tumor-bearing mouse liver.
Carcinoma, Ehrlich Tumor
Biosynthesis of an O-alkyl analogue of phosphatidic acid and O-alkylglycerols via O-alkyl ketone intermediates by microsomal enzymes of Ehrlich ascites tumor.
Carcinoma, Ehrlich Tumor
Initiation of poly-N-acetyllactosamine chain biosynthesis occurs preferentially on complex multiantennary asparagine-linked oligosaccharides.
Carcinoma, Ehrlich Tumor
The role of acyldihydroxyacetone phosphate, reduced nicotinamide adenine dinucleotide, and reduced nicotinamide adenine dinucleotide phosphate in the biosynthesis of O-alkyl glycerolipids by microsomal enzymes of Ehrlich ascites tumor.
Carcinoma, Embryonal
Induction of differentiation of embryonal carcinoma cells by retinol: possible mechanisms.
Carcinoma, Embryonal
Microsomal aromatase in testicular tumour tissue: increased activity in choriocarcinoma compared to embryonal carcinoma.
Carcinoma, Embryonal
Reverse transcriptase activity from human embryonal carcinoma cells NTera2D1.
Carcinoma, Hepatocellular
A MICROSOMAL DIFFERENCE BETWEEN NORMAL LIVER AND "MINIMAL-DEVIATION" HEPATOMA 5123 DETECTABLE BY ELECTRON SPIN RESONANCE.
Carcinoma, Hepatocellular
A novel protocol for the subcellular fractionation of C3A hepatoma cells using sucrose density gradient centrifugation.
Carcinoma, Hepatocellular
A role for Sp1 in the transcriptional regulation of hepatic triacylglycerol hydrolase in the mouse.
Carcinoma, Hepatocellular
Abnormal membrane phospholipid content in subcellular fractions from the Morris 7777 hepatoma.
Carcinoma, Hepatocellular
Abnormal microsomal cytochromes and electron transport in Morris hepatomas.
Carcinoma, Hepatocellular
Activation of heme oxygenase and heat shock protein 70 genes by stress in human hepatoma cells.
Carcinoma, Hepatocellular
An alternatively processed mRNA specific for gamma-glutamyl transpeptidase in human tissues.
Carcinoma, Hepatocellular
ARP-1/COUP-TF II determines hepatoma phenotype by acting as both a transcriptional repressor of microsomal triglyceride transfer protein and an inducer of CYP7A1.
Carcinoma, Hepatocellular
Arylamidases of rat liver and chemically induced hepatomas. 1. Subcellular distribution of L-leucine. 2. Naphthylamidase-active antigens.
Carcinoma, Hepatocellular
Bacterial Lipid II Analogs: Novel In Vitro Substrates for Mammalian Oligosaccharyl Diphosphodolichol Diphosphatase (DLODP) Activities.
Carcinoma, Hepatocellular
Cell surface expression and bile acid transport function of one topological form of m-epoxide hydrolase.
Carcinoma, Hepatocellular
Characterization of microsomal methyl sterol demethylase in two Morris hepatomas.
Carcinoma, Hepatocellular
Chemical, enzymatic, and cytochrome assays of microsomal fraction of hepatomas with different growth rates.
Carcinoma, Hepatocellular
Comparative study on fucosylation of chicken liver and virus-induced hepatoma Mc-29.
Carcinoma, Hepatocellular
Comparison of co-cultivation of V79 cells with rat hepatocytes and rat H4IIE hepatoma cells for studying nitrosamine-induced hprt gene mutations.
Carcinoma, Hepatocellular
Coordinate transcriptional repression of liver fatty acid-binding protein and microsomal triglyceride transfer protein blocks hepatic very low density lipoprotein secretion without hepatosteatosis.
Carcinoma, Hepatocellular
Correlation of fatty acyl composition of mitochondrial and microsomal phospholipid with growth rate of rat hepatomas.
Carcinoma, Hepatocellular
Covalent binding of the carcinogen trichloroethylene to hepatic microsomal proteins and to exogenous DNA in vitro.
Carcinoma, Hepatocellular
Cytidine 5'-triphosphate-dependent dolichol kinase and dolichol phosphatase activities and levels of dolichyl phosphate in microsomal fractions from highly differentiated human hepatomas.
Carcinoma, Hepatocellular
Cytochrome P-450 deficiency and resistance to t-butyl hydroperoxide of hepatoma microsomal lipid peroxidation.
Carcinoma, Hepatocellular
delta9 Desaturase activity in normal mouse liver and hepatoma SS1K.
Carcinoma, Hepatocellular
Detection of epoxide hydrolase in rat hepatoma cell lines and primary rat liver cells by immunoblotting.
Carcinoma, Hepatocellular
Development and validation of in vitro induction assays for toxic halogenated aromatic mixtures: a review.
Carcinoma, Hepatocellular
Development of monoclonal antibodies to human microsomal epoxide hydrolase and analysis of "preneoplastic antigen"-like molecules.
Carcinoma, Hepatocellular
Different properties of microsomal UDP-glucuronyltransferase in buffalo rat liver and a clonal strain of rat hepatoma cells derived from the same rat strain.
Carcinoma, Hepatocellular
Distribution of microsomal epoxide hydrolase in humans: an immunohistochemical study in normal tissues, and benign and malignant tumours.
Carcinoma, Hepatocellular
Distribution of microsomal triglyceride transfer protein within sub-endoplasmic reticulum regions in human hepatoma cells.
Carcinoma, Hepatocellular
Drug metabolism in the Novikoff hepatoma: evidence for a mixed function oxidase system and partial purification of cytochrome P-450 reductase.
Carcinoma, Hepatocellular
Effect of interleukin-11 on the levels of mRNAs encoding heme oxygenase and haptoglobin in human HepG2 hepatoma cells.
Carcinoma, Hepatocellular
Effect of Morris 7777 hepatoma on microsomal glucose-6-phosphatase latent activity.
Carcinoma, Hepatocellular
Effect of nonspecific phospholipid transfer protein on cholesterol esterification in microsomes from Morris hepatomas.
Carcinoma, Hepatocellular
Effects of 3-methylcholanthrene pretreatment on microsomal hydroxylation of 2-acetamidofluorene by various rat hepatomas.
Carcinoma, Hepatocellular
Enhancing effect of a phorbol ester and of retinoic acid on glucocorticoid induction of chenodeoxycholate hydroxylation in hepatoma cultures.
Carcinoma, Hepatocellular
Epoxide hydrolase: a marker for experimental hepatocarcinogenesis.
Carcinoma, Hepatocellular
Evaluation of a human hepatoma cell line as a target cell in genetic toxicology.
Carcinoma, Hepatocellular
Expression of microsomal and cytosolic epoxide hydrolases in cultured rat hepatocytes and hepatoma cell lines.
Carcinoma, Hepatocellular
Flavonolignan 2,3-dehydroderivatives: Preparation, antiradical and cytoprotective activity.
Carcinoma, Hepatocellular
Galactosyltransferase: multiple forms in serum of normal and hepatoma Mc-29 bearing chickens and from liver and hepatoma microsomal and plasma membrane preparations.
Carcinoma, Hepatocellular
Glutathione-S-transferase and microsomal epoxide hydrolase polymorphism and viral-related hepatocellular carcinoma risk in India.
Carcinoma, Hepatocellular
Haplotypes of Microsomal Epoxide Hydrolase and X-Ray Cross-Complementing Group 1 Genes in Indian Hepatocellular Carcinoma Patients.
Carcinoma, Hepatocellular
Heat shock induction of heme oxygenase mRNA in human Hep 3B hepatoma cells.
Carcinoma, Hepatocellular
Heme oxygenase is a positive acute-phase reactant in human Hep3B hepatoma cells.
Carcinoma, Hepatocellular
Hepatic transcriptional up-regulator of the rat microsomal epoxide hydrolase gene.
Carcinoma, Hepatocellular
Hepatitis C virus production by human hepatocytes dependent on assembly and secretion of very low-density lipoproteins.
Carcinoma, Hepatocellular
Heterogeneity in the rate of benzo[a]pyrene metabolism in single cells: quantitation using flow cytometry.
Carcinoma, Hepatocellular
Identification of replication-competent HSV-1 Cgal+ strain signaling targets in human hepatoma cells by functional organelle proteomics.
Carcinoma, Hepatocellular
Immunoaffinity purification and partial amino acid sequence analysis of catechol-O-methyltransferase from pig liver.
Carcinoma, Hepatocellular
Immunochemical comparison of human and rhesus monkey liver microsomal and the hepatocellular carcinoma-induced human serum epoxide hydrolases (preneoplastic antigens): basis for an enzyme-linked immunoabsorbent assay.
Carcinoma, Hepatocellular
Immunochemical specificity of placental NADPH cytochrome c (P-450) reductase in neoplastic and non-neoplastic human tissue.
Carcinoma, Hepatocellular
Immunochemical studies of microsomal membranes of rat preneoplastic and neoplastic hepatocytes.
Carcinoma, Hepatocellular
Immunofluorescent localization of type II insulin-like growth factor receptor in rat liver and hepatoma cells.
Carcinoma, Hepatocellular
Immunohistochemical assessment of human microsomal epoxide hydrolase in primary and secondary liver neoplasm: a quantitative approach.
Carcinoma, Hepatocellular
Induction of cytochrome P-450 1A1 in human hepatoma HepG2 and lung carcinoma NCI-H322 cells by motorcycle exhaust particulate.
Carcinoma, Hepatocellular
Induction of epoxide hydrolase in cultured rat hepatocytes and hepatoma cell lines.
Carcinoma, Hepatocellular
Inhibition of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in Morris hepatoma 7800 after intravenous injection of mevalonic acid.
Carcinoma, Hepatocellular
Inhibition of hepatocyte apoB secretion by naringenin: enhanced rapid intracellular degradation independent of reduced microsomal cholesteryl esters.
Carcinoma, Hepatocellular
Inhibition of net HepG2 cell apolipoprotein B secretion by the citrus flavonoid naringenin involves activation of phosphatidylinositol 3-kinase, independent of insulin receptor substrate-1 phosphorylation.
Carcinoma, Hepatocellular
Investigation of the rate-determining microsomal reaction of cholesterol biosynthesis from lanosterol in Morris hepatomas and liver.
Carcinoma, Hepatocellular
Lack of association of EPHX1 gene polymorphisms with risk of hepatocellular carcinoma: a meta-analysis.
Carcinoma, Hepatocellular
LINC00205 modulates the expression of EPHX1 through the inhibition of miR-184 in hepatocellular carcinoma as a ceRNA.
Carcinoma, Hepatocellular
Lipid composition, physical state, and lipid peroxidation of tumor membranes.
Carcinoma, Hepatocellular
Lipid peroxidation in cancer cells: chemical and physical studies.
Carcinoma, Hepatocellular
Lipid peroxidation of the microsomal fraction and extracted microsomal lipids from DAB-induced hepatomas.
Carcinoma, Hepatocellular
Lipoprotein profiles of hepatic cell lines at various stages of differentiation.
Carcinoma, Hepatocellular
Long-term changes in mitochondrial outer membrane enzymes and microsomal enzymes involved in drug and heme metabolism during 2-acetylaminofluorene feeding.
Carcinoma, Hepatocellular
Mechanism of action of 2,3,7,8-tetrachlorodibenzo-p-dioxin antagonists: characterization of 6-[125I]methyl-8-iodo-1,3-dichlorodibenzofuran-Ah receptor complexes.
Carcinoma, Hepatocellular
Meta-analysis of microsomal epoxide hydrolase gene polymorphism and risk of hepatocellular carcinoma.
Carcinoma, Hepatocellular
Metabolic activation of chemicals to mutagenic carcinogens by human hepatoma microsomal extracts in Chinese hamster ovary cells (in vitro).
Carcinoma, Hepatocellular
Metabolic characteristics and enflurane defluorination of cytochrome P450-dependent monooxygenases in human hepatocellular carcinoma.
Carcinoma, Hepatocellular
Microsomal cytochrome P-450-linked monooxygenase systems and lipid composition of human hepatocellular carcinoma.
Carcinoma, Hepatocellular
Microsomal N-demethylation and the effect of the hepatic carcinogen dimethylnitrosamine on amino acid incorporation into the proteins of rat livers and hepatomas.
Carcinoma, Hepatocellular
Microsomal triglyceride transfer protein is essential for hepatic secretion of apoB-100 and apoB-48 but not triglyceride.
Carcinoma, Hepatocellular
Monooxygenase, epoxide hydrolase, and glutathione-S-transferase activities in human lung. Variation between groups of bronchogenic carcinoma and non-cancer patients and interindividual differences.
Carcinoma, Hepatocellular
Multiple forms of chicken liver and hepatoma Mc-29 microsomal and plasma-membrane sialyl and fucosyltransferases.
Carcinoma, Hepatocellular
Ornithine decarboxylase lability in 2 transplantable highly deviated rat hepatomas.
Carcinoma, Hepatocellular
Partial characterization of microsomal sialyltransferase from chicken liver and hepatoma Mc-29: I. Effect of nucleotides and metal ions.
Carcinoma, Hepatocellular
Partial characterization of microsomal sialyltransferase from chicken liver and hepatoma Mc-29: II. Measurement of enzyme activities utilizing microsomal glycoproteins as exogenous acceptors.
Carcinoma, Hepatocellular
Pattern of sialoglycoproteins obtained by chromatofocusing of chicken liver and hepatoma Mc-29 microsomal preparations labelled in vivo with 3H-leucine and N-acetyl-14C-mannosamine.
Carcinoma, Hepatocellular
Phenobarbital stimulation of cytochrome P-450 and aminopyrine N-demethylase in hyperplastic liver nodules during LD-ethionine carcinogenesis.
Carcinoma, Hepatocellular
Phosphatidylserine biosynthesis in mitochondria from the Morris 7777 hepatoma.
Carcinoma, Hepatocellular
Phospholipid content of mitochondrial and microsomal membranes from Morris hepatomas of varying growth rates.
Carcinoma, Hepatocellular
Polymorphisms in xenobiotic metabolism-related genes in patients with hepatocellular carcinoma: a case-control study.
Carcinoma, Hepatocellular
Polymorphisms of the gene for microsomal epoxide hydrolase and susceptibility to alcoholic liver disease and hepatocellular carcinoma in a Caucasian population.
Carcinoma, Hepatocellular
Preparation and properties of a Met-tRNAf binding factor from rat liver and rat hepatoma.
Carcinoma, Hepatocellular
Proceedings: Activation and induction of microsomal UDPglucuronosyltransferases in rat liver and Morris hepatomas.
Carcinoma, Hepatocellular
Prolonged inhibition of cholesterol synthesis by atorvastatin inhibits apo B-100 and triglyceride secretion from HepG2 cells.
Carcinoma, Hepatocellular
Properties of aldehyde dehydrogenas from chemically-induced rat hepatomas and normal rat liver.
Carcinoma, Hepatocellular
Prostaglandin biosynthetic capacity of hepatomas with different growth rates.
Carcinoma, Hepatocellular
Protein turnover in microsomal subfractions of liver and Morris hepatomas 7800 and 9618A.
Carcinoma, Hepatocellular
Proteomic Analysis Reveals that EPHX1 Contributes to 5-Fluorouracil Resistance in a Human Hepatocellular Carcinoma Cell Line.
Carcinoma, Hepatocellular
Recent advances in elucidating the role of the microsomal triglyceride transfer protein in apolipoprotein B lipoprotein assembly.
Carcinoma, Hepatocellular
Regulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase in rat liver and Morris hepatomas 5123C, 9618A and 5123t.c.
Carcinoma, Hepatocellular
Regulation of microsomal, xenobiotic epoxide hydrolase messenger RNA in persistent hepatocyte nodules and hepatomas induced by chemical carcinogens.
Carcinoma, Hepatocellular
Relationship between cytochrome P450 catalytic cycling and stability: fast degradation of ethanol-inducible cytochrome P450 2E1 (CYP2E1) in hepatoma cells is abolished by inactivation of its electron donor NADPH-cytochrome P450 reductase.
Carcinoma, Hepatocellular
Relationship between the microsomal epoxide hydrolase and the hepatocellular transport of bile acids and xenobiotics.
Carcinoma, Hepatocellular
Reversible phosphorylation of 3-hydroxy-3-methylglutaryl CoA reductase in Morris hepatomas.
Carcinoma, Hepatocellular
Role of genetic polymorphism of glutathione-S-transferase T1 and microsomal epoxide hydrolase in aflatoxin-associated hepatocellular carcinoma.
Carcinoma, Hepatocellular
Role of lipid transfer proteins in the abnormal lipid content of Morris hepatoma mitochondria and microsomes.
Carcinoma, Hepatocellular
Role of metabolism in the activation of dehydroepiandrosterone as a peroxisome proliferator.
Carcinoma, Hepatocellular
Selective fast degradation of cytochrome P-450 2E1 in serum-deprived hepatoma cells by a mechanism sensitive to inhibitors of vesicular transport.
Carcinoma, Hepatocellular
Selective induction of microsomal 2-acetylaminofluorene N-hydroxylation by dietary 2-acetylaminofluorene in rats.
Carcinoma, Hepatocellular
Serum epoxide hydrolase (preneoplastic antigen) in human and experimental liver injury.
Carcinoma, Hepatocellular
Sesquiterpenoids Isolated from the Flower Buds of Tussilago farfara L. Inhibit Diacylglycerol Acyltransferase.
Carcinoma, Hepatocellular
Sialidase of rat hepatomas: qualitative and quantitative comparison with rat liver sialidase.
Carcinoma, Hepatocellular
Study of the in vitro bioactivation of albendazole in human liver microsomes and hepatoma cell lines.
Carcinoma, Hepatocellular
Sulfhydryl group quantitation of hepatoma and liver microsomal fractions.
Carcinoma, Hepatocellular
Superoxide dismutase content and microsomal lipid composition of tumours with different growth rates.
Carcinoma, Hepatocellular
Superoxide dismutase depletion and lipid peroxidation in rat liver microsomal membranes: correlation with liver carcinogenesis.
Carcinoma, Hepatocellular
Superoxide-dependent lipid peroxidation and vitamin E content of microsomes from hepatomas with different growth rates.
Carcinoma, Hepatocellular
The acyl-CoA desaturases of microsomes from rat liver and the Morris 7777 hepatoma.
Carcinoma, Hepatocellular
The anticancer enzyme DT diaphorase is induced selectively in liver during ascites hepatoma growth.
Carcinoma, Hepatocellular
The composition and metabolism of microsomal and mitochondrial membrane lipids in the Morris 7777 hepatoma.
Carcinoma, Hepatocellular
The expression of cytochrome P-450, epoxide hydrolase, and glutathione S-transferase in hepatocellular carcinoma.
Carcinoma, Hepatocellular
The inhibition of microsomal triglyceride transfer protein activity in rat hepatoma cells promotes proteasomal and nonproteasomal degradation of apoprotein b100.
Carcinoma, Hepatocellular
The late addition of core lipids to nascent apolipoprotein B100, resulting in the assembly and secretion of triglyceride-rich lipoproteins, is independent of both microsomal triglyceride transfer protein activity and new triglyceride synthesis.
Carcinoma, Hepatocellular
The lipid composition of highly differentiated human hepatomas, with special reference to fatty acids.
Carcinoma, Hepatocellular
The occurrence of carbonyl reduction in continuous cell lines emphasizes the essentiality of this metabolic pathway.
Carcinoma, Hepatocellular
The role of delta-6- and delta-9-desaturase in the fatty acid metabolism of hepatomas with different growth rate.
Carcinoma, Hepatocellular
The synthesis of sphingomyelin in the Morris hepatomas 7777 and 5123D is restricted to the plasma membrane.
Carcinoma, Hepatocellular
Transcriptional and post-transcriptional regulation of the asialoglycoprotein receptor in normal and neoplastic rat liver.
Carcinoma, Hepatocellular
Turnover of the plasma membrane proteins of hepatoma tissue culture cells.
Carcinoma, Hepatocellular
Turnover of the plasma-membrane and microsomal proteins of rat liver containing primary hepatoma nodules.
Carcinoma, Hepatocellular
Vitamin K-dependent carboxylase activity, prothrombin mRNA, and prothrombin production in two cultured rat hepatoma cell lines.
Carcinoma, Hepatocellular
[Accelerated microsomal DNA synthesis under the influence of xenobiotics and chemical carcinogens]
Carcinoma, Hepatocellular
[Differing microsomal monoxygenase activity in the cells of ascitic and solid forms of transplantable tumors]
Carcinoma, Hepatocellular
[Effect of 5-fluorouracil and thiophosphamide on the activity and fractional content of phosphatases of Zajdela hepatoma]
Carcinoma, Hepatocellular
[EPHX1 Tyr113His polymorphism contributes to hepatocellular carcinoma risk: evidfnce from a meta-analysis].
Carcinoma, Hepatocellular
[Photodynamic action of hypocrellin A on hepatoma cell mitochondria and microsomes]
Carcinoma, Hepatocellular
[Presence of an acid p-nitrophenylphosphatse in the microsomal fraction of a transplantable hepatoma in rats]
Carcinoma, Hepatocellular
[Purification of human microsomal epoxide hydrolase and study on its localization in hepatocellular carcinoma tissue]
Carcinoma, Hepatocellular
[Study of the microsomal factors controlling protein synthesis in cell-free systems of liver and hepatoma]
Carcinoma, Hepatocellular
[Subcellular particles in tumors. II. Analysis of mitochondrial and microsomal fractions in hepatoma HW by isopycnic centrifugation]
Carcinoma, Hepatocellular
[The lipid composition of microsomal fractions in the liver and hepatoma]
Carcinoma, Intraductal, Noninfiltrating
Increased Breast Density Correlates with the Proliferation-Seeking Radiotracer (99m)Tc(V)-DMSA Uptake in Florid Epithelial Hyperplasia and in Mixed Ductal Carcinoma In Situ with Invasive Ductal Carcinoma but Not in Pure Invasive Ductal Carcinoma or in Mild Epithelial Hyperplasia.
Carcinoma, Medullary
[Enzymohistochemical and immunomorphological study of experimental thyroid gland carcinoma]
Carcinoma, Mucoepidermoid
Microsomal fatty acid desaturation and elongation in a human lung carcinoma grown in nude mice.
Carcinoma, Non-Small-Cell Lung
Genetic polymorphism and gene expression of microsomal epoxide hydrolase in non-small cell lung cancer.
Carcinoma, Non-Small-Cell Lung
NAD+-linked 15-hydroxyprostaglandin dehydrogenase (15-PGDH) behaves as a tumor suppressor in lung cancer.
Carcinoma, Ovarian Epithelial
Xenobiotic-Metabolizing gene polymorphisms and ovarian cancer risk.
Carcinoma, Ovarian Epithelial
[Relation Between microsomal epoxide hydrolase polymorphism and susceptibility to ovarian epithelial cancer]
Carcinoma, Papillary
Loss of microsomal antigen in follicular and papillary carcinoma of the thyroid. An immunofluorescence and electron-microscopic study.
Carcinoma, Renal Cell
CYP1A1 activity in renal cell carcinoma and in adjacent normal renal tissue.
Carcinoma, Renal Cell
Estrogen 2- and 4-hydroxylase activity, catechol estrogen formation, and implications for estrogen carcinogenesis in the hamster kidney.
Carcinoma, Renal Cell
Identification of Enzymes Oxidizing the Tyrosine Kinase Inhibitor Cabozantinib: Cabozantinib Is Predominantly Oxidized by CYP3A4 and Its Oxidation Is Stimulated by cyt b5 Activity.
Carcinoma, Renal Cell
Monoclonal antibody to a proximal nephrogenic renal antigen: immunohistochemical analysis of formalin-fixed, paraffin-embedded human renal cell carcinomas.
Carcinoma, Squamous Cell
Aminopeptidase M and dipeptidyl peptidase IV activity in epithelial skin tumors: a histochemical study.
Carcinoma, Squamous Cell
Association of CYP1A1 and microsomal epoxide hydrolase polymorphisms with lung squamous cell carcinoma.
Carcinoma, Squamous Cell
Expression of cyclooxygenase-2 and microsomal prostagalandin E synthase-1 in head and neck squamous cell carcinoma.
Carcinoma, Squamous Cell
Induction of arachidonate 12-lipoxygenase mRNA by epidermal growth factor in A431 cells.
Carcinoma, Squamous Cell
Molecular basis of basal cell carcinoma: analysis of differential gene expression by differential display PCR and expression array.
Carcinoma, Squamous Cell
Monooxygenase, epoxide hydrolase, and glutathione-S-transferase activities in human lung. Variation between groups of bronchogenic carcinoma and non-cancer patients and interindividual differences.
Carcinoma, Squamous Cell
Polymorphisms in metabolizing enzymes and the risk of head and neck squamous cell carcinoma in the Slavic population of the central Europe.
Carcinoma, Squamous Cell
The interaction between microsomal epoxide hydrolase polymorphisms and cumulative cigarette smoking in different histological subtypes of lung cancer.
Carcinosarcoma
Decreased activities of liver microsomal drug-metabolizing enzymes in the rats bearing Walker carcinosarcoma.
Carcinosarcoma
Differential effects of Walker 256 carcinosarcoma cells growing subcutaneously, intramuscularly, or intraperitoneally on hepatic microsomal mixed-function oxygenase activity.
Cardiomyopathies
Abnormalities in heart membranes and myofibrils during bacterial infective cardiomyopathy in the rabbit.
Cardiomyopathies
Association of annexin A5 with Na+/Ca2+ exchanger and caveolin-3 in non-failing and failing human heart.
Cardiomyopathies
Biphasic changes in the sarcolemmal phosphatidylethanolamine N-methylation activity in catecholamine-induced cardiomyopathy.
Cardiomyopathies
[The status of the ethanol-oxidizing enzyme systems in fatal alcohol poisonings]
Cardiomyopathy, Alcoholic
Alcoholic cardiomyopathy. II. The inhibition of cardiac microsomal protein synthesis by acetaldehyde.
Cardiotoxicity
Biochemical pharmacology and DNA-drug interactions by Cl-958, a new antitumor intercalator derived from a series of substituted 2H-[1]benzothiopyrano[4,3,2-cd]indazoles.
Cardiotoxicity
Design, biochemical pharmacology, electrochemistry and tumour biology of anti-tumour anthrapyrazoles.
Cardiotoxicity
In vitro DNA strand scission and inhibition of nucleic acid synthesis in L1210 leukemia cells by a new class of DNA complexers, the anthra[1,9-cd]pyrazol-6(2H)-ones (anthrapyrazoles).
Cardiotoxicity
Microsomal lipid peroxidation induced by adriamycin, epirubicin, daunorubicin and mitoxantrone: a comparative study.
Cardiotoxicity
[Effect of biological membrane stabilizing drugs (coenzyme Q10, dextran sulfate and reduced glutathione) on adriamycin (doxorubicin)-induced toxicity and microsomal lipid peroxidation in mice]
Cardiovascular Diseases
eNOSI4 and EPHX1 polymorphisms affect maternal susceptibility to preeclampsia: analysis of five polymorphisms predisposing to cardiovascular disease in 279 Caucasian and 241 African women.
Cardiovascular Diseases
Genotype at the P554L Variant of the Hexose-6 Phosphate Dehydrogenase Gene Is Associated with Carotid Intima-Medial Thickness.
Cardiovascular Diseases
Microsomal triglyceride transfer protein -164 T > C gene polymorphism and risk of cardiovascular disease: results from the EPIC-Potsdam case-cohort study.
Cardiovascular Diseases
The effect of ghee (clarified butter) on serum lipid levels and microsomal lipid peroxidation.
Cataplexy
Search for neuron-specific and nonneuron-specific antibodies in narcoleptic patients with and without HLA DQB1*0602.
Cataract
Glaucoma following congenital cataract surgery--the role of early surgery and posterior capsulotomy.
Chagas Disease
Epitopes common to Trypanosoma cruzi and mammalian tissues are recognized by sera from Chagas' disease patients: prognosis value in Chagas disease.
Chemical and Drug Induced Liver Injury
Defensive nature of Sargassum polycystum (Brown alga) against acetaminophen-induced toxic hepatitis in rats: role of drug metabolizing microsomal enzyme system, tumor necrosis factor-alpha and fate of liver cell structural integrity.
Chemical and Drug Induced Liver Injury
Drug-induced liver injury and microsomal arylamidase activity in needle biopsy of human liver.
Chemical and Drug Induced Liver Injury
Recurrent episodes of acute hepatitis associated with LKM-1 (cytochrome P450 2D6) antibodies in identical twin brothers.
Chemical and Drug Induced Liver Injury
Toxicological significance of mechanism-based inactivation of cytochrome p450 enzymes by drugs.
Chemical and Drug Induced Liver Injury
[Phosphatidylcholine-induced repair of damaged hepatocyte membranes in heliotrine poisoning]
Chemical and Drug Induced Liver Injury
[Tienilic acid-induced hepatitis associated with liver/kidney microsomal antibody (author's transl)]
Chloracne
Relationship of basic research in toxicology to environmental standard setting: the case of polybrominated biphenyls in Michigan.
Cholangitis, Sclerosing
Organ and non-organ specific autoantibody titres and IgG levels as markers of disease activity: a longitudinal study in childhood autoimmune liver disease.
Cholangitis, Sclerosing
Significance of extractable nuclear antigens in childhood autoimmune liver disease.
Cholelithiasis
Hepatic 3-hydroxy-3-methylglutaryl coenzyme A reductase activity and biliary lipid composition in man: relation to cholesterol gallstone disease and effects of cholic acid and chenodeoxycholic acid treatment.
Cholelithiasis
Hepatic HMGCoA reductase in human cholelithiasis: effects of chenodeoxycholic and ursodeoxycholic acids.
Cholelithiasis
Hepatic microsomal activities of cholesterol 7 alpha-hydroxylase and 3-hydroxy-3-methylglutaryl-CoA reductase in the prairie dog. An animal model for cholesterol gallstone disease.
Cholelithiasis
Increased activity of hepatic microsomal triglyceride transfer protein and bile acid synthesis in gallstone disease.
Cholelithiasis
Normal antipyrine metabolism in patients with cholesterol cholelithiasis. Evidence that the disease is not due to generalized hepatic microsomal dysfunction.
Cholelithiasis
Novel sterol 7 alpha-hydroxylase(s), microsomal 27-hydroxycholesterol 7 alpha-hydroxylase, in cholesterol gallstone disease and its etiological significance.
Cholelithiasis
The effect of phenobarbital on biliary lipid metabolism and hepatic microsomal drug metabolism in patients with cholesterol cholelithiasis.
Cholelithiasis
The plasma level of 7 alpha-hydroxy-4-cholesten-3-one reflects the activity of hepatic cholesterol 7 alpha-hydroxylase in man.
Cholera
GTP-dependent ADP-ribosylation of a 22 kDa protein in the endoplasmic reticulum membrane.
Cholera
Induction of synthesis of bovine adrenocortical cytochromes P-450scc, P-45011 beta, P-450C21, and adrenodoxin by prostaglandins E2 and F2 alpha and cholera toxin.
Cholera
Transient antibodies against homologous hepatic microsomal and mitochondrial antigens in a vervet immunized with standard cholera vaccine.
Cholestasis
Autoimmune hepatitis type-2 and Epstein-Barr virus infection in a toddler: art of facts or an artifact?
Cholestasis
BCNU-induced quantitative and qualitative changes in hepatic cytochrome P-450 can be correlated with cholestasis.
Cholestasis
Bile acids produce a generalized reduction of the catalytic activity of cytochromes P450 and other hepatic microsomal enzymes in vitro: relevance to drug metabolism in experimental cholestasis.
Cholestasis
Caffeine demethylation measured by breath analysis in experimental liver injury in the rat.
Cholestasis
Chemotherapy of larval echinococcosis with mebendazole: microsomal liver function and cholestasis as determinants of plasma drug level.
Cholestasis
Cholestasis as an in vivo model for analysis of the induction of liver microsomal monooxygenases by sodium phenobarbital and 3-methylcholanthrene.
Cholestasis
Comparison of rifampicin with phenobarbitone for treatment of pruritus in biliary cirrhosis.
Cholestasis
Effect of cholestasis produced by bile duct ligation on hepatic heme and hemoprotein metabolism in rats.
Cholestasis
Effect of subchronic cholestasis on microsomal mixed-function oxidases and the glutathione-conjugating enzyme system in rat liver.
Cholestasis
Effects of bile duct ligation on hepatic expression of female-specific CYP2C12 in male and female rats.
Cholestasis
Effects of bile duct obstruction and decompression on hepatic microsomal mixed function oxidase system in rats.
Cholestasis
Effects of high taurocholate load on activities of hepatic alcohol metabolizing enzymes.
Cholestasis
Effects of liver injury and cholestasis on microsomal enzyme activities and metabolism of halothane, enflurane and methoxyflurane in vivo in rats.
Cholestasis
Hepatic adenine nucleotides and microsomal cholesterol 7 alpha-hydroxylase activity in the obstructed and freely draining lobes of the liver after selective bile duct obstruction.
Cholestasis
Inhibition of NADPH-induced microsomal lipid peroxidation in the livers of cholestatic rats.
Cholestasis
Liver metabolic zonation in rat biliary cirrhosis: distribution is reverse of that in toxic cirrhosis.
Cholestasis
Liver microsomal bilirubin UDP-glucuronyltransferase disturbances in bile duct ligated rats.
Cholestasis
Liver microsomal phospholipid fatty acids behavior and its relationship to bilirubin UDP-glucuronyltransferase activity in bile duct ligated rats.
Cholestasis
Mechanism of cholestasis. 1. Effect of bile acids on microsomal cytochrome P-450 dependent biotransformation system in vitro.
Cholestasis
Mechanism of cholestasis. 2. Effect of bile acids on the microsomal electron transfer system in vitro.
Cholestasis
Mechanism of cholestasis. 3. Interaction of synthetic detergents with the microsomal cytochrome P-450 dependentbiotransformation system in vitro. A comparison between the effects of detergents, the effects of bile acids, and the findings in bile duct ligated rats.
Cholestasis
Microsomal and peroxisomal fatty acid oxidation in bile duct ligated rats: a comparative study between liver and kidney.
Cholestasis
Microsomal and peroxisomal fatty acid oxidation in liver of rats with bile duct ligation and two-thirds hepatectomy.
Cholestasis
Microsomal drug metabolism during alpha-naphthylisothiocyanate-induced cholestasis.
Cholestasis
Microsomal function in biliary obstructed rats: effects of S-adenosylmethionine.
Cholestasis
Non-uniformity of Changes in Drug-Metabolizing Enzymes and Transporters in Liver Cirrhosis: Implications for Drug Dosage Adjustment.
Cholestasis
Prevention of lithocholate--induced cholestasis by cycloheximide, an inhibitor of protein synthesis.
Cholestasis
Regulation of renal cytochrome P-450. Effects of two-thirds hepatectomy, cholestasis, biliary cirrhosis and post-necrotic cirrhosis on hepatic and renal microsomal enzymes.
Cholestasis
Reversible bile acid changes in bile duct obstruction and its potential for hepatocellular injury.
Cholestasis
Rhabdomyolysis in a patient taking simvastatin after addition of cyclosporine therapy.
Cholestasis
Suppression of bile acid synthesis, but not of hepatic cholesterol 7alpha-hydroxylase expression, by obstructive cholestasis in humans.
Cholestasis
The hepatic microsomal mixed-function oxidase system in man: cofactor effects and the influence of cholestasis.
Cholestasis
Tissue distribution and induction of the rat multidrug resistance-associated proteins 5 and 6.
Cholestasis
[6,8-Dimethyl-2-piperidinomethyl-2,3-dihydrothiazolo[2,3-f]xanthine: a new inductor of the monooxygenase system inhibits experimental intrahepatic cholestasis in rats]
Cholestasis
[Chemical structure of the endoplasmic reticulum and function of the microsomal biotransformation system of liver cells in experimental cholestasis in the rat]
Cholestasis
[Inhibition of the antioxidant protection, microsomal oxidation, and xenobiotic glucuroconjugation in rats with cholestasis and their regulation]
Cholestasis
[Mechanism of inhibition of rat liver microsomal monooxygenases during the development of cholestasis]
Cholestasis
[Phospholipid composition of the hepatic microsomal membrane and its relationship to bilirubin UDP glucuronyltransferase in human cholestasis]
Cholestasis, Extrahepatic
[Increase of acetaminophen conjugation ability in experimental cholestasis]
Cholestasis, Intrahepatic
Effect of phenobarbital on hyperbilirubinemia, bile acid metabolism, and microsomal enzyme activity in chronic intrahepatic cholestasis of childhood.
Cholestasis, Intrahepatic
Intrahepatic cholestasis: a review of biochemical-pathological mechanisms.
Cholestasis, Intrahepatic
Selective reduction of hepatic cytochrome P450 content in patients with intrahepatic cholestasis. A mechanism for impairment of microsomal drug oxidation.
Choline Deficiency
Biosynthesis of liver microsomal phosphatidyl cholines during the development of choline deficiency.
Choline Deficiency
Effects of long-term choline deficiency on hepatic microsomal cytochrome P-450-mediated steroid and xenobiotic hydroxylases in the female rat.
Choline Deficiency
Ethanolamine kinase activity and compositions of diacylglycerols, phosphatidylcholines and phosphatidylethanolamines in livers of choline-deficient rats.
Choline Deficiency
Liver microsomal phosphatidyl choline biosynthesis in choline deficiency.
Choline Deficiency
Phosphatidylethanolamine levels and regulation of phosphatidylethanolamine N-methyltransferase.
Choline Deficiency
The effect of choline deficiency on the activity of a phosphatidylcholine-requiring enzyme: activity and properties of UDP-glucuronyltransferase in choline-deficient rats.
Chondrosarcoma
Incorporation of mannose 6-phosphate receptors into liposomes. Receptor topography and binding of alpha-mannosidase.
Chorioamnionitis
Differential expression and regulation of microsomal prostaglandin E(2) synthase in human fetal membranes and placenta with infection and in cultured trophoblast cells.
Choriocarcinoma
Biochemistry and pharmacology of 7alpha-substituted androstenediones as aromatase inhibitors.
Choriocarcinoma
Microsomal aromatase in testicular tumour tissue: increased activity in choriocarcinoma compared to embryonal carcinoma.
Chronic Periodontitis
Biosynthesis of prostaglandin E2 and F2 alpha in gingiva of patients with chronic periodontitis.
Chronic Urticaria
Association of chronic urticaria and angioedema with thyroid autoimmunity.
Chronic Urticaria
Correlation of serum antithyroid microsomal antibody and autologous serum skin test in patients with chronic idiopathic urticaria.
Chronic Urticaria
IgE antithyroid microsomal antibodies in a patient with chronic urticaria.
Chronic Urticaria
Steroid-resistant chronic urticaria associated with anti-thyroid microsomal antibodies in a nine-year-old boy.
Chronic Urticaria
Treatment of chronic urticaria with thyroxine in an euthyroid patient with thyroglobulin and microsomal antibodies.
Cleft Lip
Genetic differences in phenytoin pharmacokinetics. In vivo clearance and in vitro metabolism among inbred strains of mice.
Cleft Palate
2,2',4,4',5,5'-hexachlorobiphenyl as a 2,3,7,8-tetrachlorodibenzo-p-dioxin antagonist in C57BL/6J mice.
Cocarcinogenesis
Benzo[a]pyrene uptake into rat liver microsomes: effects of adsorption of benzo[a]pyrene to asbestos and non-fibrous mineral particulates.
Colitis
Decreased drug penetration in inflamed tissue related to changed mucosal metabolism in experimental colitis.
Colitis
Intestinal epithelium-specific knockout of the cytochrome P450 reductase gene exacerbates dextran sulfate sodium-induced colitis.
Colitis
Intestine-Specific Mttp Deletion Increases the Severity of Experimental Colitis and Leads to Greater Tumor Burden in a Model of Colitis Associated Cancer.
Colitis, Ulcerative
Leukocyte migration test in Crohn's disease, ulcerative colitis, and ankylosing spondylitis using Crohn's colon homogenate, mitochondrial, and microsomal fractions.
Colitis-Associated Neoplasms
Intestine-Specific Mttp Deletion Increases the Severity of Experimental Colitis and Leads to Greater Tumor Burden in a Model of Colitis Associated Cancer.
Colonic Neoplasms
In vitro metabolism of nitric oxide-donating aspirin: the effect of positional isomerism.
Colonic Neoplasms
Microsomal epoxide hydrolase gene polymorphism and susceptibility to colon cancer.
Colonic Neoplasms
Microsomal epoxide hydrolase polymorphisms are not associated with colon cancer risk.
Colonic Neoplasms
Tumor microsomal metabolism of the food toxicant, benzo(a)pyrene, in Apc( Min ) mouse model of colon cancer.
Colorectal Neoplasms
15-deoxy-Delta12,14-prostaglandin J2 inhibits the expression of microsomal prostaglandin E synthase type 2 in colon cancer cells.
Colorectal Neoplasms
5-Fluorouracil prodrug: role of anabolic and catabolic pathway modulation in therapy of colorectal cancer.
Colorectal Neoplasms
A pharmacogenetic study to investigate the role of dietary carcinogens in the etiology of colorectal cancer.
Colorectal Neoplasms
Association between allelic polymorphisms of metabolizing enzymes (CYP 1A1, CYP 1A2, CYP 2E1, mEH) and occurrence of colorectal cancer in Hungary.
Colorectal Neoplasms
Association between exposure-relevant polymorphisms in CYP1B1, EPHX1, NQO1, GSTM1, GSTP1 and GSTT1 and risk of colorectal cancer in a Czech population.
Colorectal Neoplasms
Epoxide hydrolase and CYP2C9 polymorphisms, cigarette smoking, and risk of colorectal carcinoma in the Nurses' Health Study and the Physicians' Health Study.
Colorectal Neoplasms
Genetic variation in genes for the xenobiotic-metabolizing enzymes CYP1A1, EPHX1, GSTM1, GSTT1, and GSTP1 and susceptibility to colorectal cancer in Lynch syndrome.
Colorectal Neoplasms
Glycosylation of the tandem repeat unit of the MUC2 polypeptide leading to the synthesis of the Tn antigen.
Colorectal Neoplasms
Interactions between cigarette smoking and selected polymorphisms in xenobiotic metabolizing enzymes in risk for colorectal cancer: A case-only analysis.
Colorectal Neoplasms
Investigation of a Possible Relationship Between EPHX1 Gene Polymorphisms and Colorectal Cancer in Turkish Society.
Colorectal Neoplasms
Meat, vegetables and genetic polymorphisms and the risk of colorectal carcinomas and adenomas.
Colorectal Neoplasms
Microsomal epoxide hydrolase polymorphisms, cigarette smoking, and risk of colorectal cancer: The Fukuoka Colorectal Cancer Study.
Colorectal Neoplasms
Microsomal glutathione S-transferase gene polymorphisms and colorectal cancer risk in a Han Chinese population.
Colorectal Neoplasms
Molecular characterization of cellular proteins from colorectal tumors.
Colorectal Neoplasms
Next-generation sequencing reveals lymph node metastasis associated genetic markers in colorectal cancer.
Colorectal Neoplasms
NQO1 and mEH exon 4 (mEH4) gene polymorphisms, smoking and colorectal cancer risk.
Colorectal Neoplasms
Positive and negative regulation of prostaglandin E2 biosynthesis in human colorectal carcinoma cells by cancer chemopreventive agents.
Colorectal Neoplasms
Prostaglandins induce early growth response 1 transcription factor mediated microsomal prostaglandin E2 synthase up-regulation for colorectal cancer progression.
Colorectal Neoplasms
Role of microsomal prostaglandin E synthase-1 (mPGES-1)-derived prostaglandin E2 in colon carcinogenesis.
Colorectal Neoplasms
Sialyltransferase activity and hepatic tumor growth in a nude mouse model of colorectal cancer metastases.
Colorectal Neoplasms
Systematic Review and Meta-Analysis of the Relationship between EPHX1 Polymorphisms and Colorectal Cancer Risk.
Colorectal Neoplasms
Vegetable, fruit and meat consumption and potential risk modifying genes in relation to colorectal cancer.
Colorectal Neoplasms
[Trends in nonsteroidal anti-inflammatory drug development and application]
Colorectal Neoplasms, Hereditary Nonpolyposis
Genetic variation in genes for the xenobiotic-metabolizing enzymes CYP1A1, EPHX1, GSTM1, GSTT1, and GSTP1 and susceptibility to colorectal cancer in Lynch syndrome.
Communicable Diseases
[Non-organ specific anticytoplasmic autoantibodies. Immunoserologic detection and diagnostic relevance]
Congenital Abnormalities
Application of kinetic polymerase chain reaction and molecular beacon assays to pooled analyses and high-throughput genotyping for candidate genes.
Congenital Abnormalities
Differences in phenytoin biotransformation and susceptibility to congenital malformations: a review.
Congenital Abnormalities
Maternal EPHX1 polymorphisms and risk of phenytoin-induced congenital malformations.
Congenital, Hereditary, and Neonatal Diseases and Abnormalities
The Tyr113His polymorphism in exon 3 of the microsomal epoxide hydrolase gene is a risk factor for perinatal mortality.
Connective Tissue Diseases
Immunoblotting as a confirmatory test for antimitochondrial antibodies in primary biliary cirrhosis.
Coronary Disease
Association of a microsomal triglyceride transfer protein gene polymorphism with blood pressure in Japanese women.
Coronary Disease
High-density lipoproteins and hepatic microsomal enzyme induction in alcohol consumers.
Coronary Disease
Inverse relationship of serum LDL cholesterol and the LDL/HDL cholesterol ratio to liver microsomal enzyme induction in man.
Coronary Disease
Plasma high-density lipoproteins and liver lipids and proteins in man. Relation to hepatic histology and microsomal enzyme induction.
Coronary Disease
The microsomal triglyceride transfer protein gene-493T variant lowers cholesterol but increases the risk of coronary heart disease.
Coronary Disease
[The status of the ethanol-oxidizing enzyme systems in fatal alcohol poisonings]
Coronary Occlusion
Alterations in heart membrane calcium transport during the development of ischemia-reperfusion injury.
Coronary Occlusion
Ischemia-induced alterations in myocardial (Na+ + K+)-ATPase and cardiac glycoside binding.
Craniofacial Abnormalities
Maternal EPHX1 polymorphisms and risk of phenytoin-induced congenital malformations.
Crigler-Najjar Syndrome
The presence of a microsomal UDP-glucuronyl transferase for bilirubin in homozygous jaundiced Gunn rats and in the Crigler-Najjar syndrome.
Crohn Disease
Genetic association between EPHX1 and Crohn's disease: population stratification, genotyping error, or random chance?
Crohn Disease
Genetic polymorphisms in biotransformation enzymes in Crohn's disease: association with microsomal epoxide hydrolase.
Crohn Disease
Leucocyte migration studies in Crohn's disease using Crohn's colon homogenate and mitochondrial and microsomal fractions.
Crohn Disease
Leukocyte migration test in Crohn's disease, ulcerative colitis, and ankylosing spondylitis using Crohn's colon homogenate, mitochondrial, and microsomal fractions.
Cryoglobulinemia
Previous tuberculosis, hepatitis C virus and lichen planus. A report of 10 cases, a causal or casual link?
Cryptorchidism
Down-regulation of steroidogenic cytochrome P450XVII in cryptorchid rat testes.
Cushing Syndrome
Steroid 21-hydroxylase and 17 alpha-hydroxylase in microsomal fraction of functioning adrenocortical tumors.
Cystic Fibrosis
Calcium- and CaMKII-dependent chloride secretion induced by the microsomal Ca(2+)-ATPase inhibitor 2,5-di-(tert-butyl)-1,4-hydroquinone in cystic fibrosis pancreatic epithelial cells.
Cystic Fibrosis
Effect of cystic fibrosis and non-cystic fibrosis plasma on 45Ca and 35SO4 uptake and retention by the small intestine at the cellular level in the guinea pig.
Cystic Fibrosis
Genetics of chronic obstructive pulmonary disease, beyond a1-antitrypsin deficiency.
Cystic Fibrosis
Membrane insertion, processing, and topology of cystic fibrosis transmembrane conductance regulator (CFTR) in microsomal membranes.
Cystic Fibrosis
Properties of chloride-conductive pathways in rat kidney cortical and outer-medulla brush-border membranes--inhibition by anti-(cystic fibrosis transmembrane regulator) mAbs.
Cystic Fibrosis
Properties of microsomal glycoprotein galactosyltransferase of cultured human fibroblasts in relation to cystic fibrosis.
Cystic Fibrosis
[A new pathogenic hypothesis of mucoviscidosis: hyperactivity of microsomal glycosyl-transferases]
Cystic Fibrosis
[Role of polymorphic variants of cytochrome P450 genes (CYP1A1, CYP2E1) and microsomal epoxide hydrolase (mEPHX) in pathogenesis of cystic fibrosis and chronic respiratory tract diseases]
Dehydration
Association between Membrane Phase Properties and Dehydration Injury in Soybean Axes.
Dehydration
Cyclooxygenase-2, prostaglandin synthases, and prostaglandin H2 metabolism in traumatic brain injury in the rat.
Dehydration
Demonstration that menthofuran synthase of mint (Mentha) is a cytochrome P450 monooxygenase: cloning, functional expression, and characterization of the responsible gene.
Dehydration
Effect of dehydration, food deprivation, saline and adrenalectomy on microsomal (Na + +K + )-dependent ATPase in the salivary glands and intestinal mucosa.
Dehydration
Effect of dehydration, starvation and sodium deprivation on microsomal ATPase in the kidney.
Dehydration
Enzymes converting D-3-hydroxyacyl-CoA to trans-2-enoyl-CoA. Microsomal and peroxisomal isoenzymes in rat liver.
Dehydration
Heterocyclic polycyclic aromatic hydrocarbon carcinogenesis: 7H-dibenzo[c,g]carbazole metabolism by microsomal enzymes from mouse and rat liver.
Dehydration
In vitro metabolism of diarylpyrazoles, a novel group of cannabinoid receptor ligands.
Dehydration
Involvement of Cytochrome P-450 in the Biosynthesis of Dhurrin in Sorghum bicolor (L.) Moench.
Dehydration
Metabolic activation of n-butyraldoxime by rat liver microsomal cytochrome P450. A requirement for the inhibition of aldehyde dehydrogenase.
Dehydration
Nitric oxide reduces hydrogen peroxide accumulation involved in water stress-induced subcellular anti-oxidant defense in maize plants.
Dehydration
P450-catalyzed in-chain desaturation of valproic acid: isoform selectivity and mechanism of formation of Delta 3-valproic acid generated by baculovirus-expressed CYP3A1.
Dehydration
Stability of diacylglycerol acyltransferase in dehydrated bovine muscle tissue.
Dehydration
Stereoselective formations of K-region and non-K-region epoxides in the metabolism of chrysene by rat liver microsomal cytochrome P-450 isozymes.
Dehydration
Studies on the in vitro conversion of haloperidol to a potentially neurotoxic pyridinium metabolite.
Dehydration
Studies on the metabolism of haloperidol (HP): the role of CYP3A in the production of the neurotoxic pyridinium metabolite HPP+ found in rat brain following ip administration of HP.
Depression, Postpartum
Maternal thyroid peroxidase antibodies during pregnancy: a marker of impaired child development?
Depression, Postpartum
Microsomal antibodies during gestation in relation to postpartum thyroid dysfunction and depression.
Dermatitis Herpetiformis
The prevalence of thyroid autoantibodies in dermatitis herpetiformis.
Dermatitis Herpetiformis
Thyroid abnormalities in dermatitis herpetiformis. Prevalence of clinical thyroid disease and thyroid autoantibodies.
Dermatitis, Allergic Contact
Subcellular fractions from dermis and epidermis in contact sensitization of guinea pigs to 1-chloro-2,4-dinitrobenzene.
Dermatitis, Atopic
[Study of liver function in babies with atopic dermatitis by using 13C-methacetin breath test]
Dermatitis, Contact
Contact sensitivity in vitro. The significance of microsomal fractions as antigens in contact sensitivity.
Dermatitis, Contact
Heme oxygenase induction mediates the photoimmunoprotective activity of UVA radiation in the mouse.
Dermatomyositis
Effects of immunosuppressive treatment on microsomal prostaglandin E synthase 1 and cyclooxygenases expression in muscle tissue of patients with polymyositis or dermatomyositis.
Diabetes Mellitus
Antithyroid antibodies in Hispanic patients with type I diabetes mellitus. Prevalence and significance.
Diabetes Mellitus
Effect of long-term anticonvulsant therapy on glucose metabolism in humans.
Diabetes Mellitus
Effect of metformin on renal microsomal proteins, lipid peroxidation and antioxidant status in dexamethasone-induced type-2 diabetic mice.
Diabetes Mellitus
Effect of the microsomal triglyceride transfer protein -493 G/T polymorphism and type 2 diabetes mellitus on LDL subfractions.
Diabetes Mellitus
Evaluation of the microsomal glutathione S-transferase 3 (MGST3) locus on 1q23 as a Type 2 diabetes susceptibility gene in Pima Indians.
Diabetes Mellitus
Frequency of Hashimoto's thyroiditis in children with type 1 diabetes mellitus.
Diabetes Mellitus
Lack of induction of serum gamma-glutamyltransferase in diabetes mellitus.
Diabetes Mellitus
Metabolic activation of troglitazone: identification of a reactive metabolite and mechanisms involved.
Diabetes Mellitus
Possible role of microsomal epoxide hydrolase gene polymorphism as a risk factor for developing insulin resistance and type 2 diabetes mellitus.
Diabetes Mellitus
Prevalence of abnormal thyrotropin concentrations measured by a sensitive assay in patients with type 2 diabetes mellitus.
Diabetes Mellitus
Separate influences of insulin and hyperglycemia on hepatic drug metabolism in mice with genetic and chemically induced diabetes mellitus.
Diabetes Mellitus
The effect of diabetes mellitus on aortic prostanoid synthesis and serum cholesterol levels in the rat fed a high cholesterol diet.
Diabetes Mellitus
The effect of streptozotocin-induced diabetes mellitus on urinary excretion of sodium and renal Na+-K+-ATPase activity.
Diabetes Mellitus
Thyroglobulin and microsomal antibodies in patients with insulin dependent diabetes mellitus and their relatives.
Diabetes Mellitus
Thyroid autoantibodies in black and in white children and adolescents with type 1 diabetes mellitus and their first degree relatives.
Diabetes Mellitus
Thyroid autoimmunity in type 2 (non-insulin-dependent) diabetic patients of Caucasoid, black and Mexican origin.
Diabetes Mellitus
[Antitoxic function of the liver and the effect of zixorin in patients with diabetes mellitus]
Diabetes Mellitus
[Evaluation of hepatic microsomal enzyme activity using C-l4-labeled aminopyrine breath test in patients with diabetes mellitus type 2 treated with tolbutamide]
Diabetes Mellitus
[Systemic autoantibodies and their correction in patients with diabetic retinopathy in type 1 diabetes mellitus]
Diabetes Mellitus
[Thyroglobulin and microsomal antibodies in diabetes mellitus in childhood (author's transl)]
Diabetes Mellitus, Experimental
Altered microsomal phospholipid composition in the streptozotocin diabetic rat.
Diabetes Mellitus, Experimental
Changes in the activity of NADH-oxidase in rat tissues during experimental diabetes.
Diabetes Mellitus, Experimental
Effect of experimental diabetes on the fatty acid composition, molecular species of phosphatidyl-choline and physical properties of hepatic microsomal membranes.
Diabetes Mellitus, Experimental
Induction and suppression of renal and hepatic cytochrome P450-dependent monooxygenases by acute and chronic streptozotocin diabetes in hamsters.
Diabetes Mellitus, Experimental
The effect of alloxan diabetes on the activity of some mixed function oxidases in male rats.
Diabetes Mellitus, Experimental
[Interrelation of the processes of lipid peroxidation and hydroxylation in the liver microsomal fraction of white rats with alloxan diabetes]
Diabetes Mellitus, Experimental
[Oxidative processes and phospholipid metabolism in hepatocyte membranes during alloxan diabetes]
Diabetes Mellitus, Lipoatrophic
EPHX1 mutations cause a lipoatrophic diabetes syndrome due to impaired epoxide hydrolysis and increased cellular senescence.
Diabetes Mellitus, Type 1
A possible mechanism of insulin resistance in the rat adipose cell in streptozotocin-induced diabetes mellitus. Depletion of intracellular glucose transport systems.
Diabetes Mellitus, Type 1
Adrenal autoantibodies and Addison disease in insulin-dependent diabetes mellitus.
Diabetes Mellitus, Type 1
Autoantibodies in recent onset type-1 diabetic patients to a Mr 60K microsomal hepatic protein: new evidence for autoantibodies to the type-2 glucose transporter.
Diabetes Mellitus, Type 1
Effect of long-term anticonvulsant therapy on glucose metabolism in humans.
Diabetes Mellitus, Type 1
Epidemiology of insulin dependent diabetes before age 20 in Wisconsin, with particular reference to seasonality.
Diabetes Mellitus, Type 1
Frequency of Hashimoto's thyroiditis in children with type 1 diabetes mellitus.
Diabetes Mellitus, Type 1
Prevalence of islet cell and thyrogastric autoantibodies in Sudanese patients with type 1 diabetes.
Diabetes Mellitus, Type 1
Thyroid peroxidase antibodies in children with autoimmune thyroiditis.
Diabetes Mellitus, Type 1
Thyroid, gastric, and adrenal autoimmunities associated with insulin-dependent diabetes mellitus.
Diabetes Mellitus, Type 1
Thyroid-stimulating immunoglobulins in insulin-dependent diabetes mellitus.
Diabetes Mellitus, Type 1
[Thyroglobulin and microsome autoantibodies and their clinical significance in adult type I diabetics]
Diabetes Mellitus, Type 1
[Thyroid hormone anomalies in patients with insulin-dependent diabetes mellitus and circulating antithyroid microsomal antibodies]
Diabetes Mellitus, Type 2
A common functional exon polymorphism in the microsomal triglyceride transfer protein gene is associated with type 2 diabetes, impaired glucose metabolism and insulin levels.
Diabetes Mellitus, Type 2
Cellular mechanisms of insulin resistance in non-insulin-dependent (type II) diabetes.
Diabetes Mellitus, Type 2
Effect of the microsomal triglyceride transfer protein -493 G/T polymorphism and type 2 diabetes mellitus on LDL subfractions.
Diabetes Mellitus, Type 2
Enzyme inducers improve insulin sensitivity in non-insulin-dependent diabetic subjects.
Diabetes Mellitus, Type 2
Evaluation of the microsomal glutathione S-transferase 3 (MGST3) locus on 1q23 as a Type 2 diabetes susceptibility gene in Pima Indians.
Diabetes Mellitus, Type 2
Messenger RNA levels of genes involved in dysregulation of postprandial lipoproteins in type 2 diabetes: the role of Niemann-Pick C1-like 1, ATP-binding cassette, transporters G5 and G8, and of microsomal triglyceride transfer protein.
Diabetes Mellitus, Type 2
Microsomal triglyceride transfer protein polymorphisms and lipoprotein levels in type 2 diabetes.
Diabetes Mellitus, Type 2
Plasma HDL cholesterol and blood glucose in non-insulin-dependent diabetics related to liver lipids and microsomal enzyme activity.
Diabetes Mellitus, Type 2
Possible role of microsomal epoxide hydrolase gene polymorphism as a risk factor for developing insulin resistance and type 2 diabetes mellitus.
Diabetes Mellitus, Type 2
Regulation of putative fatty acid transporters and Acyl-CoA synthetase in liver and adipose tissue in ob/ob mice.
Diabetes Mellitus, Type 2
Treatment of noninsulin-dependent diabetes mellitus with enzyme inducers.
Diabetes Mellitus, Type 2
[Determination of autoantibodies to pancreatic beta-cells, non-islet endocrine cells and fibroblasts in patients with newly detected diabetes mellitus]
Diabetes, Gestational
Autoantibodies in black women with class A1 or class GB diabetes mellitus.
Diabetic Nephropathies
Effects of vitamin E on microsomal Ca(2+) -ATPase activity and calcium levels in streptozotocin-induced diabetic rat kidney.
Diabetic Retinopathy
Expression of cyclo-oxygenase-2 and downstream enzymes in diabetic fibrovascular epiretinal membranes.
Diabetic Retinopathy
[Systemic autoantibodies and their correction in patients with diabetic retinopathy in type 1 diabetes mellitus]
Digestive System Diseases
Serum gamma-glutamyl transferase activity in chronic renal failure during regular hemodialysis and after successful renal transplantation.
Diphtheria
Mutation induction by okadaic acid, a protein phosphatase inhibitor, in CHL cells, but not in S. typhimurium.
Disorder of Sex Development, 46,XY
Male pseudohermaphroditism due to multiple defects in steroid-biosynthetic microsomal mixed-function oxidases. A new variant of congenital adrenal hyperplasia.
DNA Repair-Deficiency Disorders
Association between polymorphisms of EPHX1 and XRCC1 genes and the risk of childhood acute lymphoblastic leukemia.
Drug-Related Side Effects and Adverse Reactions
Characterization of the microsomal epoxide hydrolase gene in patients with anticonvulsant adverse drug reactions.
Drug-Related Side Effects and Adverse Reactions
Decreases in phenytoin hydroxylation activities catalyzed by liver microsomal cytochrome P450 enzymes in phenytoin-treated rats.
Drug-Related Side Effects and Adverse Reactions
Effect of four-day treatment with carbamazepine at different dose levels on microsomal enzyme induction, drug metabolism and drug toxicity.
Drug-Related Side Effects and Adverse Reactions
Hepatic drug metabolism and adverse hepatic drug reactions.
Drug-Related Side Effects and Adverse Reactions
Immunofluorescence of NADPH-cytochrome c (P-450) reductase in rat and minipig tissues injected with phenobarbital.
Drug-Related Side Effects and Adverse Reactions
Immunofluorescence of phenobarbital inducible cytochrome P-450 in the hepatic lobule of normal and phenobarbital-treated rats.
Drug-Related Side Effects and Adverse Reactions
Thalidomide teratogenesis: evidence for a toxic arene oxide metabolite.
Drug-Related Side Effects and Adverse Reactions
Upper-airway obstruction and prolonged recovery from anesthesia following intranasal clotrimazole administration.
Duodenal Ulcer
[Assessment of microsomal enzyme function in liver of patients with duodenal ulcer treated with famotidine]
Duodenal Ulcer
[Evaluation of microsomal enzyme function in the liver in patients with duodenal ulcer treated with famotidine]
Duodenal Ulcer
[Evaluation of microsomal liver enzyme function in patients with duodenal ulcer treated with ranitidine]
Duodenal Ulcer
[Liver microsomal enzyme function in patients with duodenal ulcer treated with cimetidine]
Dyslipidemias
A Small Molecule Inhibitor of Enterocytic Microsomal Triglyceride Transfer Protein; SLx-4090, Biochemical, Pharmacodynamic, Pharmacokinetic and Safety Profile.
Dyslipidemias
Cholesterol: the good, the bad, and the ugly - therapeutic targets for the treatment of dyslipidemia.
Dyslipidemias
Effect of microsomal triglyceride transfer protein gene polymorphism in the promoter region on dyslipidemia in type 2 diabetic subjects.
Dyslipidemias
Emerging therapies for dyslipidemia: known knowns and known unknowns of MTP inhibitors.
Dyslipidemias
Insights into the Novel Hydrolytic Mechanism of a Diethyl 2-Phenyl-2-(2-arylacetoxy)methyl Malonate Ester-Based Microsomal Triglyceride Transfer Protein (MTP) Inhibitor.
Dyslipidemias
Intestinal rather than hepatic microsomal triglyceride transfer protein as a cause of postprandial dyslipidemia in diabetes.
Dyslipidemias
JTT-130, a novel intestine-specific inhibitor of microsomal triglyceride transfer protein, improves hyperglycemia and dyslipidemia independent of suppression of food intake in diabetic rats.
Dyslipidemias
Potential Approaches to Ameliorate Hepatic Fat Accumulation Seen with MTP Inhibition.
Dyslipidemias
PPAR/RXR Regulation of Fatty Acid Metabolism and Fatty Acid omega-Hydroxylase (CYP4) Isozymes: Implications for Prevention of Lipotoxicity in Fatty Liver Disease.
Dyslipidemias
Toward an international consensus-Integrating lipoprotein apheresis and new lipid-lowering drugs.
Echinococcosis
Albendazole treatment of echinococcosis in humans: effects on microsomal metabolism and drug tolerance.
Echinococcosis
Chemotherapy of larval echinococcosis with mebendazole: microsomal liver function and cholestasis as determinants of plasma drug level.
Eczema
[Behavior of the liver microsomal detoxification systems in experimental dinitrochlorobenzene eczema]
Encephalomalacia
The influence of dietary fatty acids and vitamin E on plasma prostanoids and liver microsomal alkane production in broiler chickens with regard to nutritional encephalomalacia.
Encephalomyelitis
Endothelial Microsomal Prostaglandin E Synthetase-1 Upregulates Vascularity and Endothelial Interleukin-1? in Deteriorative Progression of Experimental Autoimmune Encephalomyelitis.
Encephalomyelitis
Targeted lipidomics reveals mPGES-1-PGE2 as a therapeutic target for multiple sclerosis.
Encephalomyelitis, Autoimmune, Experimental
Endothelial Microsomal Prostaglandin E Synthetase-1 Upregulates Vascularity and Endothelial Interleukin-1? in Deteriorative Progression of Experimental Autoimmune Encephalomyelitis.
Encephalomyelitis, Autoimmune, Experimental
Targeted lipidomics reveals mPGES-1-PGE2 as a therapeutic target for multiple sclerosis.
Endometrial Neoplasms
Cholesterol esterification in human secretory endometrium and in endometrial cancer tissue. Demonstration of microsomal acyl-CoA-cholesterol acyl-transferase (ACAT) activity.
Endometrial Neoplasms
Studies on 17 beta-hydroxysteroid dehydrogenase in human endometrium and endometrial carcinoma. III. Partial purification and characterization of the microsomal enzyme.
Endometriosis
Expression of inducible microsomal prostaglandin E synthase in local lesions of endometriosis patients.
Endometriosis
The association of endometriosis risk and genetic polymorphisms involving dioxin detoxification enzymes: A systematic review.
Endotoxemia
Microsomal Ethanol-Oxidizing System: Success Over 50 Years and an Encouraging Future.
Endotoxemia
[The state of the microsomal oxidative system in the rat liver during fecal peritonitis]
Eosinophilia
Short-term inhalation toxicity of methanol, gasoline, and methanol/gasoline in the rat.
Epilepsy
ABCB1 c.3435C > T and EPHX1 c.416A > G polymorphisms influence plasma carbamazepine concentration, metabolism, and pharmacoresistance in epileptic patients.
Epilepsy
Antiopyrine half-life as a measure of hepatic enzyme induction: clinical applications in a chronic epileptic population.
Epilepsy
Association between EPHX1 polymorphisms and carbamazepine metabolism in epilepsy: a meta-analysis.
Epilepsy
Association of ABCB1, CYP3A4, EPHX1, FAS, SCN1A, MICA, and BAG6 polymorphisms with the risk of carbamazepine-induced Stevens-Johnson syndrome/toxic epidermal necrolysis in Chinese Han patients with epilepsy.
Epilepsy
Different EPHX1 methylation levels in promoter area between carbamazepine-resistant epilepsy group and carbamazepine-sensitive epilepsy group in Chinese population.
Epilepsy
Effects of EPHX1 and CYP3A4*22 genetic polymorphisms on carbamazepine metabolism and drug response among Tunisian epileptic patients.
Epilepsy
Effects of EPHX1, SCN1A and CYP3A4 genetic polymorphisms on plasma carbamazepine concentrations and pharmacoresistance in Chinese patients with epilepsy.
Epilepsy
Genetic profile of patients with epilepsy on first-line antiepileptic drugs and potential directions for personalized treatment.
Epilepsy
In vivo and in vitro correlation of microsomal epoxide hydrolase inhibition by progabide.
Epilepsy
Maternal EPHX1 polymorphisms and risk of phenytoin-induced congenital malformations.
Epilepsy
Pharmacokinetics of radiotracers in human plasma during positron emission tomography.
Epilepsy
Topiramate modulates hippocampus NMDA receptors via brain Ca(2+) homeostasis in pentylentetrazol-induced epilepsy of rats.
Epiretinal Membrane
Expression of cyclo-oxygenase-2 and downstream enzymes in diabetic fibrovascular epiretinal membranes.
Epstein-Barr Virus Infections
Autoimmune hepatitis type-2 and Epstein-Barr virus infection in a toddler: art of facts or an artifact?
Erythroblastosis, Fetal
[Effectiveness of a new Soviet drug Benzonal, inductor of microsomal enzymes of the liver, in the complex treatment of hemolytic disease of newborn]
Esophageal Neoplasms
Association between esophageal cancer risk and EPHX1 polymorphisms: a meta-analysis.
Esophageal Neoplasms
Association between microsomal epoxide hydrolase 1 polymorphisms and susceptibility to esophageal cancer: a meta-analysis.
Esophageal Neoplasms
CYP1A1, GSTs and mEH polymorphisms and susceptibility to esophageal carcinoma: study of population from a high- incidence area in north China.
Esophageal Neoplasms
EPHX1 polymorphisms do not modify esophageal carcinoma susceptibility in Dutch Caucasians.
Esophageal Neoplasms
EPHX1 Tyr113His and His139Arg polymorphisms in esophageal cancer risk: a meta-analysis.
Esophageal Neoplasms
High-loading nanosized micelles of copoly(styrene-maleic acid)-zinc protoporphyrin for targeted delivery of a potent heme oxygenase inhibitor.
Esophageal Neoplasms
Lack of association between EPHX1 polymorphism and esophageal cancer risk: evidence from meta-analysis.
Esophageal Neoplasms
Meta-analysis demonstrates lack of an association of microsomal epoxide hydrolase 1 polymorphisms with esophageal cancer risk.
Esophageal Neoplasms
Microsomal epoxide hydrolase (EPHX1), slow (exon 3, 113His) and fast (exon 4, 139Arg) alleles confer susceptibility to squamous cell esophageal cancer.
Esophageal Neoplasms
Role of epoxide hydrolase 1 gene polymorphisms in esophageal cancer in a high-risk area in India.
Esophageal Neoplasms
[Spermidine radioimmunoassay in monitor of precancerous lesions of esophagus]
Esophageal Squamous Cell Carcinoma
Association of Activity Altering Genotypes - Tyr113His and His139Arg in Microsomal Epoxide Hydrolase Enzyme with Esophageal Squamous Cell Carcinoma.
Esophageal Squamous Cell Carcinoma
EPHX1 polymorphisms do not modify esophageal carcinoma susceptibility in Dutch Caucasians.
Esophageal Squamous Cell Carcinoma
Epoxide hydrolase Tyr113His polymorphism is not associated with susceptibility to esophageal squamous cell carcinoma in population of North China.
Essential Hypertension
The Flavin-Containing Monooxygenase 3 Gene and Essential Hypertension: The Joint Effect of Polymorphism E158K and Cigarette Smoking on Disease Susceptibility.
Exfoliation Syndrome
Immunohistochemical analysis of microsomal glutathione S-transferase 1 and clusterin expression in lens epithelial cells of patients with pseudoexfoliation syndrome.
Exfoliation Syndrome
Quantitative analysis of SOD2, ALDH1A1 and MGST1 messenger ribonucleic acid in anterior lens epithelium of patients with pseudoexfoliation syndrome.
Exophthalmos
Immunologically mediated cytotoxicity against human eye muscle and thyroid cells in euthyroid and thyrotoxic Graves' ophthalmopathy.
Exophthalmos
Relationship of eye muscle antibodies with HLA phenotypes and thyroid-stimulating immunoglobulins in endocrine orbitopathy.
Exophthalmos
Role of thyrotropin receptor antibodies in the development of hyperthyroidism: follow-up studies on nine patients with Graves' disease.
Familial Mediterranean Fever
Oxidative stress in the molecular mechanism of pathogenesis at different diseased states of organism in clinics and experiment.
Fanconi Anemia
Abnormal microsomal detoxification implicated in Fanconi anemia group C by interaction of the FAC protein with NADPH cytochrome P450 reductase.
Fascioliasis
Antihepatotoxic properties of uridine-diphosphoglucose in liver fluke infection. Experimental fascioliasis in the rat.
Fascioliasis
Characterization of the microsomal cytochrome P-450 species inhibited in rat liver in the course of fascioliasis.
Fascioliasis
Decrease in hepatic microsomal UDP-glucuronosyl-transferase activity in rats and cattle with fascioliasis: impaired in vitro glucuronidation of oxyclozanide.
Fascioliasis
Impaired in vitro metabolism of the flukicidal agent nitroxynil by hepatic microsomal cytochrome P-450 in bovine fascioliasis.
Fascioliasis
Incidence of a subclinical fascioliasis on antipyrine clearance and metabolite excretion in sheep.
Fatty Liver
Alloxan induced fatty liver degeneration in rat: its effect on the microsomal lipids.
Fatty Liver
Altered activity of cytochrome P450 in alcoholic fatty liver exposed to ischemia/reperfusion.
Fatty Liver
Anesthetic biotransformation and renal function in obese patients during and after methoxyflurane or halothane anesthesia.
Fatty Liver
Association between microsomal triglyceride transfer protein gene polymorphism and the biological features of liver steatosis in patients with type II diabetes.
Fatty Liver
Association of polymorphisms of glutamate-cystein ligase and microsomal triglyceride transfer protein genes in non-alcoholic fatty liver disease.
Fatty Liver
Changes in hepatic microsomal triglyceride transfer protein and triglyceride in periparturient dairy cattle.
Fatty Liver
Correlation between MTP -493G>T polymorphism and non-alcoholic fatty liver disease risk: a meta-analysis.
Fatty Liver
Decreased microsomal triglyceride transfer protein activity contributes to initiation of alcoholic liver steatosis in rats.
Fatty Liver
Dietary egg white protein hydrolysate improves orotic acid-induced fatty liver in rats by promoting hepatic phospholipid synthesis and microsomal triglyceride transfer protein expression.
Fatty Liver
Dysfunction of estrogen-related receptor alpha-dependent hepatic VLDL secretion contributes to sex disparity in NAFLD/NASH development.
Fatty Liver
Effect of betaine on the hepatic damage from orotic acid-induced fatty liver development in rats.
Fatty Liver
Effect of dietary composition and estradiol implants on hepatic microsomal mixed function oxidase and lipid deposition in growing chicks.
Fatty Liver
Effect of diisopropyl 1,3-dithiol-2-ylidenemalonate (NKK-105) on fatty liver induced by carbon tetrachloride.
Fatty Liver
Effects of mineral and vitamin supplementation on the alcohol-induced fatty liver and microsomal induction.
Fatty Liver
Ethanol-related changes in liver microsomes and mitochondria from the monkey, Macaca fascicularis.
Fatty Liver
Etiology of fatty liver in dairy cattle: effects of nutritional and hormonal status on hepatic microsomal triglyceride transfer protein.
Fatty Liver
Expression and methylation of microsomal triglyceride transfer protein and acetyl-CoA carboxylase are associated with fatty liver syndrome in chicken.
Fatty Liver
Genes or environment to determine alcoholic liver disease and non-alcoholic fatty liver disease.
Fatty Liver
Genetic Association and Gene-Gene Interaction Reveal Genetic Variations in ADH1B, GSTM1 and MnSOD Independently Confer Risk to Alcoholic Liver Diseases in India.
Fatty Liver
GLP-2 Dysregulates Hepatic Lipoprotein Metabolism, Inducing Fatty Liver and VLDL Overproduction in Male Hamsters and Mice.
Fatty Liver
Hepatic gene expression changes in mouse models with liver-specific deletion or global suppression of the NADPH-cytochrome P450 reductase gene. Mechanistic implications for the regulation of microsomal cytochrome P450 and the fatty liver phenotype.
Fatty Liver
Hepatic triacylglycerol synthesizing activity during progression of alcoholic liver injury in the baboon.
Fatty Liver
L-tryptophan alleviates fatty liver and modifies hepatic microsomal mixed function oxidase in laying hens.
Fatty Liver
Lack of association between microsomal triglyceride transfer protein gene polymorphism and liver steatosis in HCV-infected patients.
Fatty Liver
Liver breath tests non-invasively predict higher stages of non-alcoholic steatohepatitis.
Fatty Liver
Liver microsomal triglyceride transfer protein is involved in hepatitis C liver steatosis.
Fatty Liver
Loss of miR-141/200c ameliorates hepatic steatosis and inflammation by reprogramming multiple signaling pathways in NASH.
Fatty Liver
Low Expression of Sirtuin 1 in the Dairy Cows with Mild Fatty Liver Alters Hepatic Lipid Metabolism.
Fatty Liver
Membrane stabilising effects of natural polyphenols and flavonoids from Sempervivum tectorum on hepatic microsomal mixed-function oxidase system in hyperlipidemic rats.
Fatty Liver
MTP -493G/T gene polymorphism is associated with steatosis in hepatitis C-infected patients.
Fatty Liver
Non-Alcoholic Steatohepatitis Decreases Microsomal Liver Function in the Absence of Fibrosis.
Fatty Liver
Non-uniformity of Changes in Drug-Metabolizing Enzymes and Transporters in Liver Cirrhosis: Implications for Drug Dosage Adjustment.
Fatty Liver
Novel Findings for the Development of Drug Therapy for Various Liver Diseases:Liver Microsomal Triglyceride Transfer Protein Activator May Be a Possible Therapeutic Agent in Non-alcoholic Steatohepatitis.
Fatty Liver
Perilipin 5 promotes hepatic steatosis in dairy cows through increasing lipid synthesis and decreasing very low density lipoprotein assembly.
Fatty Liver
Polymorphisms of microsomal triglyceride transfer protein gene and manganese superoxide dismutase gene in non-alcoholic steatohepatitis.
Fatty Liver
Prevention Mechanism of 2,3,5,4'-Tetrahydroxy-stilbene-2-O-?-D-glucoside on Lipid Accumulation in Steatosis Hepatic L-02 Cell.
Fatty Liver
Prevention of the acute ethanol-induced fatty liver by antihistamines and stimulants of hepatic microsomal enzyme activity.
Fatty Liver
Retardation of microsomal protein synthesis in rat liver due to induction of Handler's experimental fatty liver.
Fatty Liver
Sequential production of fatty liver, hepatitis, and cirrhosis in sub-human primates fed ethanol with adequate diets.
Fatty Liver
[Effects of diispropyl 1, 3-dithiol-2-ylidene malonate (NKK-105) on the drug-metabolizing enzymes and fine structure of rat liver (author's transl)]
Fatty Liver, Alcoholic
Decreased microsomal triglyceride transfer protein activity contributes to initiation of alcoholic liver steatosis in rats.
Fatty Liver, Alcoholic
Effect of ursodeoxycholic acid on prostaglandin metabolism and microsomal membranes in alcoholic fatty liver.
Fatty Liver, Alcoholic
Microsomal delta 9, delta 6 and delta 5 desaturase activities and liver membrane fatty acid profiles in alcohol-fed rats.
Fatty Liver, Alcoholic
[Mechanism of action of the SIRT1-FoxO1-AdipoR2 signaling pathway in alcoholic fatty liver disease].
Fetal Growth Retardation
The prevalence of autoantibodies during third-trimester pregnancy complicated by hypertension or idiopathic fetal growth retardation.
Fetal Resorption
[Animal experiment studies of the modification of pregnancy by heterologous antibodies to placental antigens]
Folic Acid Deficiency
Effect of folate deficiency on microsomal drug metabolism and heme content in the intestinal mucosa of guinea pigs.
Gallstones
ACAT2 and human hepatic cholesterol metabolism: Identification of important gender-related differences in normolipidemic, non-obese Chinese patients.
Gallstones
Bile acid synthesis in man: assay of hepatic microsomal cholesterol 7 alpha-hydroxylase activity by isotope dilution-mass spectrometry.
Gallstones
Hepatic acyl-coenzyme A:cholesterol acyltransferase activity is decreased in patients with cholesterol gallstones.
Gallstones
Hepatic cholesterol and bile acid metabolism in subjects with gallstones: comparative effects of short erm feeding of chenodeoxycholic and ursodeoxycholic acid.
Gallstones
Hepatic microsomal activities of cholesterol 7 alpha-hydroxylase and 3-hydroxy-3-methylglutaryl-CoA reductase in the prairie dog. An animal model for cholesterol gallstone disease.
Gallstones
Hepatic Mttp deletion reverses gallstone susceptibility in L-Fabp knockout mice.
Gallstones
Inactivation of hepatic microsomal triglyceride transfer protein protects mice from diet-induced gallstones.
Gallstones
Increased activity of hepatic microsomal triglyceride transfer protein and bile acid synthesis in gallstone disease.
Gallstones
Lack of response to chenodeoxycholic acid in obese and non-obese patients. Role of cholesterol synthesis and possible response to ursodeoxycholic acid.
Gallstones
Modulation of cholesterol 7 alpha-hydroxylase activity by nonspecific lipid transfer protein in human liver--possibly altered regulation of its cytosolic level in patients with gallstones.
Gallstones
On the saturation of the cholesterol 7 alpha-hydroxylase in human liver microsomes.
Gallstones
Possible role of a defect in hepatic bilirubin glucuronidation in the initiation of cholesterol gallstones.
Gallstones
Treatment with the natural FXR agonist chenodeoxycholic acid reduces clearance of plasma LDL whilst decreasing circulating PCSK9, lipoprotein(a) and apolipoprotein C-III.
Gangliosidosis, GM1
Filipin recognizes both GM1 and cholesterol in GM1 gangliosidosis mouse brain.
Gastroesophageal Reflux
Genetic polymorphisms of microsomal epoxide hydroxylase and glutathione S-transferases M1, T1 and P1, interactions with smoking, and risk for esophageal (Barrett) adenocarcinoma.
Gastrointestinal Diseases
Use of Nanovesicles from Orange Juice to Reverse Diet-Induced Gut Modifications in Diet-Induced Obese Mice.
Genetic Diseases, Inborn
Cell death and stress signaling in glycogen storage disease type I.
Genetic Diseases, Inborn
Characterisation of CAH alleles with non-radioactive DNA single strand conformation polymorphism analysis of the CYP21 gene.
Genetic Diseases, Inborn
Identification of two classes of lipid molecule binding sites on the microsomal triglyceride transfer protein.
Genetic Diseases, Inborn
The common P450 oxidoreductase variant A503V is not a modifier gene for 21-hydroxylase deficiency.
Genetic Diseases, Inborn
The role of the microsomal triglygeride transfer protein in abetalipoproteinemia.
Gilbert Disease
Effects of bucolome and related barbiturate derivatives on the displacement of bilirubin from plasma albumin in vivo and in vitro.
Gilbert Disease
Regulation of bilirubin glucuronide synthesis in primate (Macaca fascicularis) liver. Kinetic analysis of microsomal bilirubin uridine diphosphate glucuronyltransferase.
Glioblastoma
Development of monoclonal antibodies to human microsomal epoxide hydrolase and analysis of "preneoplastic antigen"-like molecules.
Glioma
Cytotoxicity of alkyl-lysophospholipid derivatives and low-alkyl-cleavage enzyme activities in rat brain tumor cells.
Glioma
Evidence for a GTP-dependent increase in membrane permeability for calcium in NG108-15 microsomes.
Glioma
Expression and induction of cytochrome P-450 1A1 and P-450 2D subfamily in the rat glioma C6 cell line.
Glioma
Expression, induction and regulation of the cytochrome P450 monooxygenase system in the rat glioma C6 cell line.
Glioma
Heterogeneous nuclear ribonucleoproteins and their interactors are a major class of deregulated proteins in anaplastic astrocytoma: a grade III malignant glioma.
Glioma
Identification of the putative brain tumor antigen BF7/GE2 as the (de)toxifying enzyme microsomal epoxide hydrolase.
Glioma
Induction of prostaglandin E2 synthesis and microsomal prostaglandin E synthase-1 expression in murine microglia by glioma-derived soluble factors. Laboratory investigation.
Glioma
Involvement of tyrosine kinase in capacitative Ca2+ entry pathway in rat glioma C6 cells.
Glioma
Is there a relationship between 3-hydroxy-3-methylglutaryl coenzyme a reductase activity and forebrain pathology in the PKU mouse?
Glioma
Silencing of the human microsomal glucose-6-phosphate translocase induces glioma cell death: potential new anticancer target for curcumin.
Glioma
The 1,4 benzoquinone-featured 5-lipoxygenase inhibitor RF-Id induces apoptotic death through downregulation of IAPs in human glioblastoma cells.
Glomerulonephritis
Genetic variants of microsomal metabolism and susceptibility to hydrocarbon-associated glomerulonephritis.
Glossitis
Blood profile of atrophic glossitis patients with thyroglobulin antibody/thyroid microsomal antibody positivity but without gastric parietal cell antibody positivity.
Glucose Intolerance
Dietary P(i) deprivation in rats affects liver cAMP, glycogen, key steps of gluconeogenesis and glucose production.
Glucose Intolerance
Involvement of microsomal triglyceride transfer protein in nonalcoholic steatohepatitis in novel spontaneous mouse model.
Glucose Intolerance
JTT-130, a novel intestine-specific inhibitor of microsomal triglyceride transfer protein, suppresses high fat diet-induced obesity and glucose intolerance in Sprague-Dawley rats.
Glucose Intolerance
Mechanism of action of hypoglycemic effects of an intestine-specific inhibitor of microsomal triglyceride transfer protein (MTP) in obese rats.
Glucose Intolerance
Up-regulation of liver glucose-6-phosphatase in rats fed with a P(i)-deficient diet.
glucose-6-phosphate dehydrogenase (nadp+) deficiency
Microsomal incubation test of potentially hemolytic drugs for glucose-6-phosphate dehydrogenase deficiency.
Glucosephosphate Dehydrogenase Deficiency
Microsomal incubation test of potentially hemolytic drugs for glucose-6-phosphate dehydrogenase deficiency.
glucuronosyltransferase deficiency
UDP-glucuronyltransferase-catalyzed deconjugation of bilirubin monoglucuronide.
glutathione synthase deficiency
Acetaminophen toxicity in lymphocytes heterozygous for glutathione synthetase deficiency.
glutathione synthase deficiency
Glutathione synthetase-deficient lymphocytes and acetaminophen toxicity.
Glycogen Storage Disease
A conformational model for the human liver microsomal glucose-6-phosphatase system: evidence from rapid kinetics and defects in glycogen storage disease type 1.
Glycogen Storage Disease
A direct evidence for defect in glucose-6-phosphate transport system in hepatic microsomal membrane of glycogen storage disease type IB.
Glycogen Storage Disease
Asymptomatic critical hypoglycaemia: a dangerous presentation of glycogen storage disease type Ib in infancy.
Glycogen Storage Disease
Cell death and stress signaling in glycogen storage disease type I.
Glycogen Storage Disease
Exon redefinition by a point mutation within exon 5 of the glucose-6-phosphatase gene is the major cause of glycogen storage disease type 1a in Japan.
Glycogen Storage Disease
Genomic structure of the human glucose 6-phosphate translocase gene and novel mutations in the gene of a Japanese patient with glycogen storage disease type Ib.
Glycogen Storage Disease
Glucose-6-phosphatase dependent substrate transport in the glycogen storage disease type-1a mouse.
Glycogen Storage Disease
Glucose-6-phosphatase mutation G188R confers an atypical glycogen storage disease type 1b phenotype.
Glycogen Storage Disease
Glycogen storage disease type 1a in Israel: biochemical, clinical, and mutational studies.
Glycogen Storage Disease
Glycogen storage disease type 1a in three siblings with the G270V mutation.
Glycogen Storage Disease
Glycogen storage disease type 1b: microsomal glucose-6-phosphatase system in two patients with different clinical findings.
Glycogen Storage Disease
Glycogen storage disease type I: diagnosis and phenotype/genotype correlation.
Glycogen Storage Disease
Glycogen storage disease type Ia (GSDIa) but not Glycogen storage disease type Ib (GSDIb) is associated to an increased risk of metabolic syndrome: possible role of microsomal glucose 6-phosphate accumulation.
Glycogen Storage Disease
Glycogen storage disease type Ib: a defect in the glucose-6-phosphate transport system in microsomal membrane (The Japan Society of Human Genetics Award lecture).
Glycogen Storage Disease
Glycogen storage disease type Ib: structural and mutational analysis of the microsomal glucose-6-phosphate transporter gene.
Glycogen Storage Disease
Homology modeling of the human microsomal glucose 6-phosphate transporter explains the mutations that cause the glycogen storage disease type Ib.
Glycogen Storage Disease
Identification of mutations in the gene for glucose-6-phosphatase, the enzyme deficient in glycogen storage disease type 1a.
Glycogen Storage Disease
Impaired chemotaxis and neutrophil (polymorphonuclear leukocyte) function in glycogenosis type IB.
Glycogen Storage Disease
Improved preparation of hepatic microsomes for in vitro diagnosis of inherited disorders of the glucose-6-phosphatase system.
Glycogen Storage Disease
Inactivation of the glucose 6-phosphate transporter causes glycogen storage disease type 1b.
Glycogen Storage Disease
Inhibition of microsomal glucose-6-phosphate transport in human neutrophils results in apoptosis: a potential explanation for neutrophil dysfunction in glycogen storage disease type 1b.
Glycogen Storage Disease
Liver microsomal transport of glucose-6-phosphate, glucose, and phosphate in type 1 glycogen storage disease.
Glycogen Storage Disease
Molecular analysis of glycogen storage disease type Ib: identification of a prevalent mutation among Japanese patients and assignment of a putative glucose-6-phosphate translocase gene to chromosome 11.
Glycogen Storage Disease
Mutation spectrum of glycogen storage disease type Ia in Tunisia: implication for molecular diagnosis.
Glycogen Storage Disease
Mutation spectrum of the glucose-6-phosphatase gene and its implication in molecular diagnosis of Korean patients with glycogen storage disease type Ia.
Glycogen Storage Disease
NPT4, a new microsomal phosphate transporter: mutation analysis in glycogen storage disease type Ic.
Glycogen Storage Disease
Proton MR spectroscopy of the lumbar spine in patients with glycogen storage disease type Ib.
Glycogen Storage Disease
Two new mutations in the glucose-6-phosphatase gene cause glycogen storage disease in Hungarian patients.
Glycogen Storage Disease
Type Ib glycogen storage disease is caused by a defect in the glucose-6-phosphate translocase of the microsomal glucose-6-phosphatase system.
Glycogen Storage Disease Type I
Cell death and stress signaling in glycogen storage disease type I.
Glycogen Storage Disease Type I
Glycogen storage disease type 1a in Israel: biochemical, clinical, and mutational studies.
Glycogen Storage Disease Type I
Glycogen storage disease type 1a in three siblings with the G270V mutation.
Glycogen Storage Disease Type I
Two new mutations in the glucose-6-phosphatase gene cause glycogen storage disease in Hungarian patients.
Goiter
A simple semiquantitative radiometric measurement of antithyroglobulin antibodies in human serum. Comparison with hemagglutination method.
Goiter
Cellular immunity as a valuable factor for prognostic prediction in patients with Graves' disease under antithyroid drug therapy.
Goiter
Cytologic characterization of postiodization residual goiter in schoolchildren by fine needle biopsy.
Goiter
Kentucky Appalachian goiter without iodine deficiency. Evidence for evanescent thyroiditis.
Goiter
Mixed connective tissue disease associated with idiopathic portal hypertension and chronic thyroiditis.
Goiter
Patients with endocrine ophthalmopathy not associated with overt thyroid disease have multiple thyroid immunological abnormalities.
Goiter
Practical treatment with minimum maintenance dose of anti-thyroid drugs for prediction of remission in Graves' disease.
Goiter
Prevalence of thyroid microsomal and thyroglobulin autoantibodies in goitrous lesions.
Goiter
Thyroid cancer yield in patients with Graves' disease selected for surgery on the basis of cold scintiscan defects.
Goiter
Thyroid disease and high concentration of serum thyrotrophin in a population sample of women. A 4-year follow-up.
Goiter
Valuable predictive features of relapse of Graves' disease after antithyroid drug treatment.
Goiter
[A long-term follow-up study of patients with chronic lymphocytic thyroiditis--with special reference to histological findings]
Goiter
[Characteristics of the clinical picture, hormonal status and humoral immunity in older patients with diffuse toxic goiter]
Goiter
[Cytologic differentiation between the autonomous and autoimmune type of diffuse hyperthyroid goiter: correlation with TSH receptor antibodies, microsomal antibodies and infiltrative ophthalmopathy]
Goiter
[Immunological reactivity and the HLA system antigens in patients with autoimmune thyroiditis and nodular euthyroid goiter]
Goiter
[Post-partum autoimmune thyroiditis in a patient presenting with Sheehan's syndrome]
Goiter
[The concentration of nucleic acids in the subcellular structures of the thyroid gland in several of its diseases]
Goiter
[Thyroid antibodies in autoimmune diseases of the thyroid and their dependence on the presence of autoantigens]
Goiter, Endemic
The relationship between autoimmune thyroid disease and iodine intake: a review.
Goiter, Nodular
Lack of response of peripheral blood mononuclear cells to thyroid microsomal antigen in nontoxic nodular goiters.
Granuloma
Alterations of hepatic microsomal enzymes in the early phase of murine schistosomiasis.
Graves Disease
Anterior pituitary cell antibodies detected in Hashimoto's thyroiditis and Graves' disease.
Graves Disease
Anti-nuclear antibody, anti-DNA, and aCL in Graves' disease patients treated with propyluracil or methimazole.
Graves Disease
Antibodies to the thyroid gland and to the thyrotrophin receptor in African and Indian thyrotoxic patients.
Graves Disease
Changes in serum autoantibodies to thyroid peroxidase during antithyroid drug therapy for Graves' disease.
Graves Disease
Changes of circulating thyroid autoantibody levels during and after the therapy with methimazole in patients with Graves' disease.
Graves Disease
Changes of serum anti-thyroid antibodies during and after pregnancy in autoimmune thyroid diseases.
Graves Disease
Clinical significance of anti-TSH antibody in sera from patients with Graves' disease and other thyroid disorders.
Graves Disease
Comparison of thyroperoxidase and microsomal antibody assays in sera from patients with Graves disease.
Graves Disease
Correlation of microsomal antibodies with the intensity of the intrathyroidal autoimmune process in Graves' disease.
Graves Disease
Correlation of orbital computed tomography and antibodies in patients with hyperthyroid Graves' disease.
Graves Disease
Detection of autoantibodies to thyroid peroxidase in autoimmune thyroid diseases by micro-ELISA and immunoblotting.
Graves Disease
Development of postpartum spontaneously resolving transient Graves' hyperthyroidism followed immediately by transient hypothyroidism.
Graves Disease
Discordant changes in serum anti-TSH receptor antibody and antithyroid microsomal antibody during pregnancy in autoimmune thyroid diseases.
Graves Disease
Effect of HLA-DR positive thyrocytes on in vitro thyroid autoantibody production.
Graves Disease
Effect of thyrotropin-releasing hormone on serum thyroid hormones: a study in the patients with untreated and treated Graves' disease and subacute thyroiditis.
Graves Disease
Enhanced expression of complement regulatory proteins on thyroid epithelial cells of Graves' disease.
Graves Disease
Evaluation of TSH receptor antibody by 'natural in vivo human assay' in neonates born to mothers with Graves' disease.
Graves Disease
Expression of the microsomal antigen on the surface of continuously cultured rat thyroid cells is modulated by thyrotropin.
Graves Disease
Graves' disease and Hashimoto's thyroiditis: effects of high doses of antithyroid drugs on thyroid autoantibody levels.
Graves Disease
IgG subclass distribution of thyroid autoantibodies: a 'fingerprint' of an individual's response to thyroglobulin and thyroid microsomal antigen.
Graves Disease
Immunoglobulin A class fibroblast antibodies in patients with Graves' disease and pretibial myxedema.
Graves Disease
Immunological disturbances in toxic multinodular goitre and active Graves' disease.
Graves Disease
In vitro production of interferon-gamma by peripheral blood from patients with Graves' disease, Hashimoto's thyroiditis and rheumatoid arthritis.
Graves Disease
Increased soluble interleukin 2 receptor levels in autoimmune thyroid disease.
Graves Disease
Insoluble particulate antigen(s) in cell-mediated immunity of autoimmune thyroid disease.
Graves Disease
Measurement and clinical significance of thyroid microsomal and thyroglobulin antibodies by enzyme-linked immunosorbent assay.
Graves Disease
Microsomal antigen-reactive lymphocyte lines and clones derived from thyroid tissue of patients with Graves' disease.
Graves Disease
Peripheral blood T lymphocyte sensitization to thyroid microsomal antigen from patients with Graves' disease negative for circulating anti-thyroid microsomal antibodies.
Graves Disease
Plasma membrane shedding and colloid vacuoles in hyperactive human thyroid tissue.
Graves Disease
Prediction of post-partum Graves' thyrotoxicosis by measurement of thyroid stimulating antibody in early pregnancy.
Graves Disease
Prevalence & significance of pancreatic islet cell & adrenal antibodies in patients with Graves' disease.
Graves Disease
Retrospective reevaluation of the significance of thyroid microsomal antibody in the treatment of Graves' disease.
Graves Disease
Similar effects of thionamide drugs and perchlorate on thyroid-stimulating immunoglobulins in Graves' disease: evidence against an immunosuppressive action of thionamide drugs.
Graves Disease
The changes of serum titers of thyroid antibodies in patients of Graves' disease with hyperthyroidism after treatments with antithyroid drugs.
Graves Disease
The relationship of HLA-DR3 and outcome after antithyroid drugs to the IgG subclass distribution of thyroid autoantibodies in Graves' disease.
Graves Disease
The significance of antithyroglobulin and antithyroidal microsomal antibodies in patients with hyperthyroidism due to Graves' disease treated with antithyroidal drugs.
Graves Disease
Thyroid autoantigens and their relevance in the pathogenesis of thyroid autoimmunity.
Graves Disease
[An immunoenzyme method of determining serum levels of anti-microsomal antibodies]
Graves Disease
[Profile of autoimmune antibodies in idiopathic hypothyroidism and hypothyroidism following radio-iodine treatment in Basedow's disease: comparison with a group of normal subjects from the female population of Switzerland]
Graves Disease
[The presence of antithyroid antibodies in the blood serum of patients with diffuse toxic goiter before and during treatment]
Graves Ophthalmopathy
[Cytologic differentiation between the autonomous and autoimmune type of diffuse hyperthyroid goiter: correlation with TSH receptor antibodies, microsomal antibodies and infiltrative ophthalmopathy]
Graves Ophthalmopathy
[Muscle antigens recognized with autoantibodies in patients with Graves' ophthalmopathy]
Gynecomastia
Studies on the interactions between drug and estrogen. II. On the inhibitory effect of 29 drugs reported to induce gynecomastia on the oxidation of estradiol at C-2 or C-17.
Hamartoma
Simultaneous expression of COX-2 and mPGES-1 in mouse gastrointestinal hamartomas.
Hashimoto Disease
Detection of thyroid microsomal and thyroglobulin antibodies by new sensitive radioimmunoassay in Hashimoto's disease; comparison with conventional hemagglutination assay.
Hashimoto Disease
Postpartum thyrotoxicosis in a patient with Graves' disease. Association with low radioactive iodine uptake.
Hashimoto Disease
Probing the normal and autoimmune B cell repertoire with Epstein-Barr virus. Frequency of B cells producing monoreactive high affinity autoantibodies in patients with Hashimoto's disease and systemic lupus erythematosus.
Hashimoto Disease
Sclerosing lymphocytic lobulitis of the breast--evidence for an autoimmune pathogenesis.
Head and Neck Neoplasms
Association between head and neck cancer and microsomal epoxide hydrolase genotypes.
Head and Neck Neoplasms
CYP1A1, CYP2E1, GSTM1, GSTT1, EPHX1 exons 3 and 4, and NAT2 polymorphisms, smoking, consumption of alcohol and fruit and vegetables and risk of head and neck cancer.
Head and Neck Neoplasms
Microsomal epoxide hydrolase genotypes and the risk for head and neck cancer.
Head and Neck Neoplasms
Systematic Review and Meta-Analysis of the Relationship between EPHX1 Polymorphisms and the Risk of Head and Neck Cancer.
Hearing Loss, Sensorineural
Leopard-like retinopathy and severe early-onset portal hypertension expand the phenotype of KARS1-related syndrome: a case report.
Heart Defects, Congenital
The effect on congenital heart diseases of maternal EPHX1 polymorphisms modified by polycyclic aromatic hydrocarbons exposure.
Heart Failure
Canine cardiac digitalis receptors are preserved in congestive heart failure induced by rapid ventricular pacing.
Heart Failure
Correlation between the demethylation rate of 14C-aminopyrine (breath-test) and haemodynamic parameters in congestive heart failure.
Heart Failure
Effect of congestive heart failure on the intrinsic metabolic capacity of the liver in the dog.
Heart Failure
Impairment of mitochondrial and sarcoplasmic reticular functions during the development of heart failure in cardiomyopathic (UM-X7.1) hamsters.
Heart Failure
The cyclooxygenase-1/mPGES-1/endothelial prostaglandin EP4 receptor pathway constrains myocardial ischemia-reperfusion injury.
Heart Failure
The effects of two new inotropic agents on microsomal liver function in patients with congestive heart failure.
Hepatitis
Absence of anti-trifluoroacetate antibody after halothane anaesthesia in patients exhibiting no or mild liver damage.
Hepatitis
Anti-liver endoplasmic reticulum autoantibodies are directed against human cytochrome P-450IA2. A specific marker of dihydralazine-induced hepatitis.
Hepatitis
Antibodies to liver/kidney microsome1 in chronic active hepatitis recognize specific forms of hepatic cytochrome P-450.
Hepatitis
Autoantibodies against CYP2D6 and other drug-metabolizing enzymes in autoimmune hepatitis type 2.
Hepatitis
Characterization of anti-liver kidney microsomal antibody in childhood autoimmune chronic active hepatitis: evidence for IgG1 subclass restriction, polyclonality and non cross-reactivity with hepatocyte surface antigens.
Hepatitis
Chronic active hepatitis associated with liver-kidney microsomal antibody of an autoimmune type. Two familial cases.
Hepatitis
Chronic active hepatitis associated with vitiligo, nail dystrophy, alopecia and a new variant of LKM antibodies.
Hepatitis
Clonal analysis of liver-infiltrating T cells in patients with LKM-1 antibody-positive autoimmune chronic active hepatitis.
Hepatitis
Correlation of induced drug metabolism with titer of duck hepatitis virus in chickens.
Hepatitis
Cytochromes P450 and uridine triphosphate-glucuronosyltransferases: model autoantigens to study drug-induced, virus-induced, and autoimmune liver disease.
Hepatitis
Detection of autoantibodies against M2, LKM-1, and SLA in liver diseases by standardized uniform ELISA-techniques.
Hepatitis
Detection of autoantibodies directed against human hepatic endoplasmic reticulum in sera from patients with halothane-associated hepatitis.
Hepatitis
Development of thyroid autoimmunity after administration of recombinant human interferon-alpha 2b for chronic viral hepatitis.
Hepatitis
Distinction between natural and pathological autoantibodies by immunoblotting and densitometric subtraction: liver-kidney microsomal antibody (LKM) positive sera identify multiple antigens in human liver tissue.
Hepatitis
Effect of anti-basic liver protein antibody-induced liver injury on hepatic drug-metabolizing enzymes in C57 BL/6J mice.
Hepatitis
Effect of silymarin (Carsil) on the microsomal glycoprotein and protein biosynthesis in liver of rats with experimental galactosamine hepatitis.
Hepatitis
Enflurane metabolism produces covalently bound liver adducts recognized by antibodies from patients with halothane hepatitis.
Hepatitis
Evidence for expression in human liver of halothane-induced neoantigens recognized by antibodies in sera from patients with halothane hepatitis.
Hepatitis
Factors affecting the expression of trifluoroacetylated liver microsomal protein neoantigens in rats treated with halothane.
Hepatitis
FTIR spectroscopic and HPLC chromatographic studies of carbon tetrachloride induced acute hepatitis in rats: damage in liver phospholipid membrane.
Hepatitis
Glutathione-S-transferase and microsomal epoxide hydrolase polymorphism and viral-related hepatocellular carcinoma risk in India.
Hepatitis
Halothane hepatitis patients have serum antibodies that react with protein disulfide isomerase.
Hepatitis
Haplotypes of Microsomal Epoxide Hydrolase and X-Ray Cross-Complementing Group 1 Genes in Indian Hepatocellular Carcinoma Patients.
Hepatitis
Hepatic ?(9) and ?(6) desaturase activities during the recovery period following carbon tetrachloride poisoningdesaturase activities during the recovery period following carbon tetrachloride poisoning.
Hepatitis
Hepatic autoantigens in patients with autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy.
Hepatitis
Hepatic delta 9 and delta 6 desaturase activities during the recovery period following carbon tetrachloride poisoning.
Hepatitis
Human anti-endoplasmic reticulum antibodies in sera of patients with halothane-induced hepatitis are directed against a trifluoroacetylated carboxylesterase.
Hepatitis
Identification by immunoblotting of three halothane-induced liver microsomal polypeptide antigens recognized by antibodies in sera from patients with halothane-associated hepatitis.
Hepatitis
Identification of protein disulfide isomerase and calreticulin as autoimmune antigens in LEC strain of rats.
Hepatitis
IgG subclass distribution of autoantibodies to glomerular basement membrane in Goodpasture's syndrome compared to other autoantibodies.
Hepatitis
Immunoblotting as a confirmatory test for antimitochondrial antibodies in primary biliary cirrhosis.
Hepatitis
Inhibition of microsomal lipid peroxidation and protein oxidation by extracts from plants used in bamun folk medicine (cameroon) against hepatitis.
Hepatitis
Liver cell surface expression of the antigen reacting with liver-kidney microsomal antibody (LKM).
Hepatitis
Low-titre auto-antibodies predict autoimmune disease during interferon-alpha treatment of chronic hepatitis C.
Hepatitis
Major antigen of liver kidney microsomal autoantibodies in idiopathic autoimmune hepatitis is cytochrome P450db1.
Hepatitis
Metabolic basis for a drug hypersensitivity: antibodies in sera from patients with halothane hepatitis recognize liver neoantigens that contain the trifluoroacetyl group derived from halothane.
Hepatitis
Mitochondrial functions and content of microsomal and mitochondrial cytochromes in human cirrhosis.
Hepatitis
Occurrence of autoimmune antibodies to liver microsomal proteins associated with lethal hepatitis in LEC rats: effects of TJN-101 ((+)-(6S,7S,R-biar)- 5,6,7,8-tetrahydro-1,2,3,12-tetramethoxy-6,7-dimethyl-10,11- methylenedioxy-6-dibenzo[a,c]cyclooctenol) on the development of hepatitis and the autoantibodies.
Hepatitis
Occurrence of autoimmune antibodies to liver microsomal proteins in association with fulminant hepatitis in the LEC strain of rats.
Hepatitis
Processing of endoplasmic reticulum luminal antigens associated with halothane hepatitis in rat hepatocytes.
Hepatitis
Progressive familial intrahepatic cholestasis type 4 in an Indian child: presentation, initial course and novel compound heterozygous mutation.
Hepatitis
Recurrent episodes of acute hepatitis associated with LKM-1 (cytochrome P450 2D6) antibodies in identical twin brothers.
Hepatitis
Sequential production of fatty liver, hepatitis, and cirrhosis in sub-human primates fed ethanol with adequate diets.
Hepatitis
Serum antibodies from halothane hepatitis patients react with the rat endoplasmic reticulum protein ERp72.
Hepatitis
Specificity of in vitro covalent binding of tienilic acid metabolites to human liver microsomes in relationship to the type of hepatotoxicity: comparison with two directly hepatotoxic drugs.
Hepatitis
Stabilization of mitochondrial and microsomal function by polysaccharide of Ulva lactuca on D-Galactosamine induced hepatitis in rats.
Hepatitis
The application of quantitative cytochemistry to study the acinar distribution of enzymatic activities in human liver biopsy sections.
Hepatitis
The immunoelectron-microscopical demonstration of antibodies against endoplasmic reticulum (microsomes) in chronic aggressive hepatitis and liver cirrhosis.
Hepatitis
The topography of trifluoroacetylated protein antigens in liver microsomal fractions from halothane treated rats.
Hepatitis
Tienilic acid-induced autoimmune hepatitis: anti-liver and-kidney microsomal type 2 autoantibodies recognize a three-site conformational epitope on cytochrome P4502C9.
Hepatitis
Toxicological significance of mechanism-based inactivation of cytochrome p450 enzymes by drugs.
Hepatitis
Uridine diphosphate glucoronosyl transferases, candidate antigens of liver-kidney microsomal antibodies in hepatitis delta virus-infected patients.
Hepatitis
Viral load in samples from hepatitis C virus (HCV)-infected patients with various clinical conditions.
Hepatitis
[Assessment of the status of microsomal and mitochondrial oxidation in rat liver tissue in tetracycline hepatitis]
Hepatitis
[Chronic active hepatitis: recurrence after long-term immunosuppressive therapy in spite of normal liver histology]
Hepatitis
[Non-organ specific anticytoplasmic autoantibodies. Immunoserologic detection and diagnostic relevance]
Hepatitis
[Spondyloenchondrodysplasia with immune dysregulation: a case report and literature review].
Hepatitis
[The assessment of liver microsomal oxidative capacity via caffeine and antipyrine elimination in patients with chronic active hepatitis: preliminary results]
Hepatitis
[Tienilic acid-induced hepatitis associated with liver/kidney microsomal antibody (author's transl)]
Hepatitis B
Expression of genes involved in lipogenesis is not increased in patients with HCV genotype 3 in human liver.
Hepatitis B
Hepatitis B spliced protein (HBSP) promotes the carcinogenic effects of benzo [alpha] pyrene by interacting with microsomal epoxide hydrolase and enhancing its hydrolysis activity.
Hepatitis B
Microsomal Epoxide Hydrolase Polymorphisms and Haplotypes as Determinants of Hepatitis B Virusand Hepatitis C Virus-related Liver Disease in Indian Population.
Hepatitis B
Microsomal function in hepatitis B surface antigen healthy carriers: assessment of cytochrome P450 1A2 activity by the 14C-caffeine breath test.
Hepatitis B
Polymorphisms of microsomal triglyceride transfer protein in different hepatitis B virus-infected patients.
Hepatitis B
Prevalence and significance of abdominal lymphadenopathy in patients with chronic liver disease: an ultrasound study.
Hepatitis B
[Chronic active hepatitis: recurrence after long-term immunosuppressive therapy in spite of normal liver histology]
Hepatitis B, Chronic
Prevalence and significance of thyroid autoantibodies in patients with chronic hepatitis C virus infection: a prospective controlled study.
Hepatitis B, Chronic
[Autoantibodies related to interferon therapy in chronic hepatitis B may affect the therapeutic response to interferon]
Hepatitis B, Chronic
[Investigation of antinuclear antibodies in chronic hepatitis B patients].
Hepatitis C
A highly efficient and robust in vitro translation system for expression of picornavirus and hepatitis C virus RNA genomes.
Hepatitis C
A novel assay for detecting antibodies to cytochrome P4502D6, the molecular target of liver kidney microsomal antibody type 1.
Hepatitis C
A polymorphism in the microsomal triglyceride transfer protein can predict the response to antiviral therapy in Egyptian patients with chronic hepatitis C virus genotype 4 infection.
Hepatitis C
Analysis of hepatitis C virus genome in patients with autoimmune hepatitis type 2.
Hepatitis C
Anti-rat liver microsomal and cytosolic antibodies in hepatitis C virus infection.
Hepatitis C
Apolipoprotein-AII concentrations are associated with liver steatosis in patients with chronic hepatitis C.
Hepatitis C
Association between lipoprotein subfraction profile and the response to hepatitis C treatment in Japanese patients with genotype 1b.
Hepatitis C
Autoimmune hepatitis type 2 and hepatitis C virus infection: study of HLA antigens.
Hepatitis C
Characterization of the liver cytosol antigen type 1 reacting with autoantibodies in chronic active hepatitis.
Hepatitis C
Clinical features and effect of antiviral therapy on anti-liver/kidney microsomal antibody type 1 positive chronic hepatitis C.
Hepatitis C
Complete translation of the hepatitis C virus genome in vitro: membranes play a critical role in the maturation of all virus proteins except for NS3.
Hepatitis C
Determinants of the variability of aflatoxin-albumin adduct levels in Ghanaians.
Hepatitis C
Development of monoclonal antibodies to human microsomal epoxide hydrolase and analysis of "preneoplastic antigen"-like molecules.
Hepatitis C
Epitope mapping of cytochrome P4502D6 autoantigen in patients with chronic hepatitis C during alpha-interferon treatment.
Hepatitis C
Establishment of a novel radioligand assay using eukaryotically expressed cytochrome P4502D6 for the measurement of liver kidney microsomal type 1 antibody in patients with autoimmune hepatitis and hepatitis C virus infection.
Hepatitis C
Evidence of a genetic basis for the different geographic occurrences of liver/kidney microsomal antibody type 1 in hepatitis C.
Hepatitis C
Genetic variation in the microsomal triglyceride transfer protein (-493G/T) is associated with hepatic steatosis in patients infected with hepatitis C virus.
Hepatitis C
Hepatic steatosis in hepatitis C is a storage disease due to HCV interaction with microsomal triglyceride transfer protein (MTP).
Hepatitis C
Hepatitis C virus core protein inhibits microsomal triglyceride transfer protein activity and very low density lipoprotein secretion: a model of viral-related steatosis.
Hepatitis C
Hepatitis C virus infection associated with liver-kidney microsomal antibody type 1 (LKM1) autoantibodies in children.
Hepatitis C
Hepatitis C virus-related chronic liver disease with autoantibodies to liver-kidney microsomes (LKM). Clinical characterization from idiopathic LKM-positive disorders.
Hepatitis C
Heterogeneity of liver/kidney microsomal antibody type 1 in autoimmune hepatitis and hepatitis C virus related liver disease.
Hepatitis C
Immunoglobulin GM and KM allotypes and prevalence of anti-LKM1 autoantibodies in patients with hepatitis C virus infection.
Hepatitis C
Increased incidence of anti-LKM autoantibodies in a consecutive cohort of hepatitis C patients from central Greece.
Hepatitis C
Interferon therapy in liver/kidney microsomal antibody type 1-positive patients with chronic hepatitis C.
Hepatitis C
Lichen planus, liver kidney microsomal (LKM1) antibodies and hepatitis C virus antibodies.
Hepatitis C
Liver microsomal triglyceride transfer protein is involved in hepatitis C liver steatosis.
Hepatitis C
Liver/kidney microsomal antibody type 1 targets CYP2D6 on hepatocyte plasma membrane.
Hepatitis C
LKM3 autoantibodies in hepatitis C cirrhosis: a further phenomenon of the HCV-induced autoimmunity.
Hepatitis C
Low hepatitis C viremia levels in patients with anti-liver/kidney microsomal antibody type 1 positive chronic hepatitis.
Hepatitis C
Low prevalence of liver-kidney microsomal autoantibodies of type 1 (LKM1) in hepatitis C seropositive subjects on Crete, Greece.
Hepatitis C
Low-titre auto-antibodies predict autoimmune disease during interferon-alpha treatment of chronic hepatitis C.
Hepatitis C
Microsomal Epoxide Hydrolase Polymorphisms and Haplotypes as Determinants of Hepatitis B Virusand Hepatitis C Virus-related Liver Disease in Indian Population.
Hepatitis C
Microsomal triglyceride transfer protein polymorphism (-493G/T) is associated with hepatic steatosis in patients with chronic hepatitis C.
Hepatitis C
MTTP polymorphisms and hepatic steatosis in individuals chronically infected with hepatitis C virus.
Hepatitis C
Multiple viral/self immunological cross-reactivity in liver kidney microsomal antibody positive hepatitis C virus infected patients is associated with the possession of HLA B51.
Hepatitis C
Prevalence of antibodies to hepatitis C and herpes simplex virus type 1 is not increased in children with liver kidney microsomal type 1 autoimmune hepatitis.
Hepatitis C
Prevalence of GBV-C/HGV-RNA, virus genotypes, and anti-E2 antibodies in autoimmune hepatitis.
Hepatitis C
Primary and secondary liver/kidney microsomal autoantibody response following infection with hepatitis C virus.
Hepatitis C
Study of the B cell response to cytochrome P450IID6 in sera from chronic hepatitis C patients.
Hepatitis C
The levels of monoamine neurotransmitters and measures of mental and emotional health in HCV patients treated with ledipasvir (LDV) and sofosbuvir (SOF) with or without ribavirin (RBV).
Hepatitis C
Thyroid dysfunction in Chinese hepatitis C patients: Prevalence and correlation with TPOAb and CXCL10.
Hepatitis C
Transient elastography as a noninvasive assessment tool for hepatopathies of different etiology in pediatric type 1 diabetes mellitus.
Hepatitis C, Chronic
A major CYP2D6 autoepitope in autoimmune hepatitis type 2 and chronic hepatitis C is a three-dimensional structure homologous to other cytochrome P450 autoantigens.
Hepatitis C, Chronic
A polymorphism in the microsomal triglyceride transfer protein can predict the response to antiviral therapy in Egyptian patients with chronic hepatitis C virus genotype 4 infection.
Hepatitis C, Chronic
Autoantibodies and hepatitis C virus genotypes in chronic hepatitis C patients in Estonia.
Hepatitis C, Chronic
Clinical features and effect of antiviral therapy on anti-liver/kidney microsomal antibody type 1 positive chronic hepatitis C.
Hepatitis C, Chronic
Cytochrome P4502D6(193-212): a new immunodominant epitope and target of virus/self cross-reactivity in liver kidney microsomal autoantibody type 1-positive liver disease.
Hepatitis C, Chronic
Differences in immune recognition of cytochrome P4502D6 by liver kidney microsomal (LKM) antibody in autoimmune hepatitis and chronic hepatitis C virus infection.
Hepatitis C, Chronic
Evidence of a genetic basis for the different geographic occurrences of liver/kidney microsomal antibody type 1 in hepatitis C.
Hepatitis C, Chronic
Hepatitis C virus infection associated with liver-kidney microsomal antibody type 1 (LKM1) autoantibodies in children.
Hepatitis C, Chronic
Heterogeneity of antigenic sites recognized by anti-liver/kidney microsomal antibody type I in autoimmune hepatitis and chronic hepatitis C.
Hepatitis C, Chronic
Heterogeneity of liver-kidney microsomal autoantibodies in chronic hepatitis C and D virus infection.
Hepatitis C, Chronic
High prevalence of thyroid autoantibodies in a prospective series of patients with chronic hepatitis C before interferon therapy.
Hepatitis C, Chronic
Interferon and steroid treatment in patients with chronic hepatitis C and antinuclear or anti-liver-kidney microsomal antibodies.
Hepatitis C, Chronic
Interferon therapy in liver/kidney microsomal antibody type 1-positive patients with chronic hepatitis C.
Hepatitis C, Chronic
Key residues of a major cytochrome P4502D6 epitope are located on the surface of the molecule.
Hepatitis C, Chronic
Liver kidney microsomal type 1 antibodies reduce the CYP2D6 activity in patients with chronic hepatitis C virus infection.
Hepatitis C, Chronic
Microsomal triglyceride transfer protein polymorphism (-493G/T) is associated with hepatic steatosis in patients with chronic hepatitis C.
Hepatitis C, Chronic
MTP -493G/T gene polymorphism is associated with steatosis in hepatitis C-infected patients.
Hepatitis C, Chronic
Multiple viral/self immunological cross-reactivity in liver kidney microsomal antibody positive hepatitis C virus infected patients is associated with the possession of HLA B51.
Hepatitis C, Chronic
Non-organ specific autoantibodies associated with chronic C virus hepatitis.
Hepatitis C, Chronic
Parameters of microsomal and cytosolic liver function but not of liver perfusion predict portal vein velocity in noncirrhotic patients with chronic hepatitis C.
Hepatitis C, Chronic
Primary and secondary liver/kidney microsomal autoantibody response following infection with hepatitis C virus.
Hepatitis C, Chronic
Recurrent episodes of acute hepatitis associated with LKM-1 (cytochrome P450 2D6) antibodies in identical twin brothers.
Hepatitis C, Chronic
Steroid and interferon therapy in liver/kidney microsomal antibody-positive patients with chronic hepatitis C.
Hepatitis C, Chronic
[Detection and the production mechanism of antinuclear antibodies (ANA) and anti-liver/kidney microsomal tpe 1 antibodies (anti-LKM1) in patients with chronic hepatitis C]
Hepatitis C, Chronic
[Heterogeneity of antimicrosomal autoantibodies in chronic hepatitis C virus infection and delta hepatitis]
Hepatitis D
Detection and further characterization of a newly described microsomal autoantibody associated with chronic delta infection.
Hepatitis D, Chronic
Anti-GOR in hepatitis D: specific association with hepatitis C virus superinfection.
Hepatitis D, Chronic
Autoantibodies against glucuronosyltransferases differ between viral hepatitis and autoimmune hepatitis.
Hepatitis D, Chronic
Detection and further characterization of a newly described microsomal autoantibody associated with chronic delta infection.
Hepatitis D, Chronic
Recognition of uridine diphosphate glucuronosyl transferases by LKM-3 antibodies in chronic hepatitis D.
Hepatitis, Alcoholic
Aminopyrine N-demethylation: a prognostic test of liver function in patients with alcoholic liver disease.
Hepatitis, Alcoholic
Inhibition of hepatic drug metabolism by (+)-cyanidanol-3 (Catergen) in chronic alcoholic liver disease.
Hepatitis, Alcoholic
Non-organ specific autoantibodies associated with chronic C virus hepatitis.
Hepatitis, Autoimmune
A 12-year-old girl with antimitochondrial antibody-positive autoimmune hepatitis.
Hepatitis, Autoimmune
A major CYP2D6 autoepitope in autoimmune hepatitis type 2 and chronic hepatitis C is a three-dimensional structure homologous to other cytochrome P450 autoantigens.
Hepatitis, Autoimmune
A new antigen recognized by anti-liver-kidney-microsome antibody (LKMA).
Hepatitis, Autoimmune
A new epitope of CYP2D6 recognized by liver kidney microsomal autoantibody from japanese patients with autoimmune hepatitis.
Hepatitis, Autoimmune
A novel assay for detecting antibodies to cytochrome P4502D6, the molecular target of liver kidney microsomal antibody type 1.
Hepatitis, Autoimmune
Absence of LKM-1 antibody reactivity in autoimmune and hepatitis-C-related chronic liver disease in Sweden. Swedish Internal Medicine Liver club.
Hepatitis, Autoimmune
Analysis of hepatitis C virus genome in patients with autoimmune hepatitis type 2.
Hepatitis, Autoimmune
Anti-liver cytosolic antigen type 1 (LC1) antibodies in childhood autoimmune liver disease.
Hepatitis, Autoimmune
Anti-mitochondrial antibody positive autoimmune hepatitis triggered by EBV infection in a young girl.
Hepatitis, Autoimmune
Anti-rat liver microsomal and cytosolic antibodies in hepatitis C virus infection.
Hepatitis, Autoimmune
Autoantibodies against CYP2D6 and other drug-metabolizing enzymes in autoimmune hepatitis type 2.
Hepatitis, Autoimmune
Autoantibodies to human cytosol: a marker of sporadic porphyria cutanea tarda.
Hepatitis, Autoimmune
Autoimmune hepatitis type-2 and Epstein-Barr virus infection in a toddler: art of facts or an artifact?
Hepatitis, Autoimmune
Autoimmune hepatitis-specific antibodies against soluble liver antigen and liver cytosol type 1 in patients with chronic viral hepatitis.
Hepatitis, Autoimmune
Characterization of anti-liver-kidney microsome antibody (anti-LKM1) from hepatitis C virus-positive and -negative sera.
Hepatitis, Autoimmune
Characterization of the liver cytosol antigen type 1 reacting with autoantibodies in chronic active hepatitis.
Hepatitis, Autoimmune
Clinical features and effect of antiviral therapy on anti-liver/kidney microsomal antibody type 1 positive chronic hepatitis C.
Hepatitis, Autoimmune
Cytochrome P4502D6(193-212): a new immunodominant epitope and target of virus/self cross-reactivity in liver kidney microsomal autoantibody type 1-positive liver disease.
Hepatitis, Autoimmune
Cytochrome P450IID6-specific CD8 T cell immune responses mirror disease activity in autoimmune hepatitis type 2.
Hepatitis, Autoimmune
Detection of anti-endoplasmic reticulum antibody-positive autoimmune hepatitis in children, using an ELISA technique.
Hepatitis, Autoimmune
Detection of anti-liver cytosol antibody type 1 (anti-LC1) by immunodiffusion, counterimmunoelectrophoresis and immunoblotting: comparison of different techniques.
Hepatitis, Autoimmune
Differences in immune recognition of cytochrome P4502D6 by liver kidney microsomal (LKM) antibody in autoimmune hepatitis and chronic hepatitis C virus infection.
Hepatitis, Autoimmune
Distinct epitopes on formiminotransferase cyclodeaminase induce autoimmune liver cytosol antibody type 1.
Hepatitis, Autoimmune
Epitope mapping of cytochrome P4502D6 autoantigen in patients with chronic hepatitis C during alpha-interferon treatment.
Hepatitis, Autoimmune
Establishment of a novel radioligand assay using eukaryotically expressed cytochrome P4502D6 for the measurement of liver kidney microsomal type 1 antibody in patients with autoimmune hepatitis and hepatitis C virus infection.
Hepatitis, Autoimmune
Evaluation of frequency of autoimmune hepatitis autoantibodies in children with type 1 diabetes.
Hepatitis, Autoimmune
Heterogeneity of antigenic sites recognized by anti-liver/kidney microsomal antibody type I in autoimmune hepatitis and chronic hepatitis C.
Hepatitis, Autoimmune
Heterogeneity of liver/kidney microsomal antibody type 1 in autoimmune hepatitis and hepatitis C virus related liver disease.
Hepatitis, Autoimmune
Immunological cross-reactivity to multiple autoantigens in patients with liver kidney microsomal type 1 autoimmune hepatitis.
Hepatitis, Autoimmune
Interferon therapy in LKM-1 positive patients with chronic hepatitis C: follow-up by a quantitative radioligand assay for CYP2D6 antibody detection.
Hepatitis, Autoimmune
Is autoimmune hepatitis a frequent finding among HCV patients with intense interface hepatitis?
Hepatitis, Autoimmune
Key residues of a major cytochrome P4502D6 epitope are located on the surface of the molecule.
Hepatitis, Autoimmune
Liver-kidney microsomal antibody-positive autoimmune hepatitis in the United States.
Hepatitis, Autoimmune
Liver/kidney microsomal antibody type 1 and liver cytosol antibody type 1 concentrations in type 2 autoimmune hepatitis.
Hepatitis, Autoimmune
Liver/kidney microsomal antibody type 1 targets CYP2D6 on hepatocyte plasma membrane.
Hepatitis, Autoimmune
LKM-1 sera from autoimmune hepatitis patients that recognize ERp57, carboxylesterase 1 and CYP2D6.
Hepatitis, Autoimmune
Major antigen of liver kidney microsomal autoantibodies in idiopathic autoimmune hepatitis is cytochrome P450db1.
Hepatitis, Autoimmune
Multiple viral/self immunological cross-reactivity in liver kidney microsomal antibody positive hepatitis C virus infected patients is associated with the possession of HLA B51.
Hepatitis, Autoimmune
Organ and non-organ specific autoantibody titres and IgG levels as markers of disease activity: a longitudinal study in childhood autoimmune liver disease.
Hepatitis, Autoimmune
Organ-specific and non-organ-specific autoantibodies in children and young adults with autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED).
Hepatitis, Autoimmune
Pitfalls in the diagnosis of autoimmune hepatitis associated with liver and kidney microsomal proteins.
Hepatitis, Autoimmune
Polyclonal T-Cell Responses to Cytochrome P450IID6 Are Associated With Disease Activity in Autoimmune Hepatitis Type 2.
Hepatitis, Autoimmune
Prevalence of antibodies to hepatitis C and herpes simplex virus type 1 is not increased in children with liver kidney microsomal type 1 autoimmune hepatitis.
Hepatitis, Autoimmune
Prevalence of GBV-C/HGV-RNA, virus genotypes, and anti-E2 antibodies in autoimmune hepatitis.
Hepatitis, Autoimmune
Primary and secondary liver/kidney microsomal autoantibody response following infection with hepatitis C virus.
Hepatitis, Autoimmune
Recreational Exposure during Algal Bloom in Carrasco Beach, Uruguay: A Liver Failure Case Report.
Hepatitis, Autoimmune
Recurrent episodes of acute hepatitis associated with LKM-1 (cytochrome P450 2D6) antibodies in identical twin brothers.
Hepatitis, Autoimmune
Significance of extractable nuclear antigens in childhood autoimmune liver disease.
Hepatitis, Autoimmune
T cell receptor Vbeta chain restriction and preferred CDR3 motifs of liver-kidney microsomal antigen (LKM-1)-reactive T cells from autoimmune hepatitis patients.
Hepatitis, Autoimmune
Target proteins in human autoimmunity: cytochromes P450 and UDP- glucuronosyltransferases.
Hepatitis, Autoimmune
The induction of autoimmune hepatitis in the human leucocyte antigen-DR4 non-obese diabetic mice autoimmune hepatitis mouse model.
Hepatitis, Autoimmune
Tienilic acid-induced autoimmune hepatitis: anti-liver and-kidney microsomal type 2 autoantibodies recognize a three-site conformational epitope on cytochrome P4502C9.
Hepatitis, Autoimmune
Type 1 and type 2 autoimmune hepatitis in adults share the same clinical phenotype.
Hepatitis, Autoimmune
[Fatal bleeding complications caused by Evans syndrome (autoimmune thrombocytopenia and hemolytic anemia) and type II autoimmune hepatitis in a 56-year-old patient]
Hepatitis, Autoimmune
[Heterogeneity of antimicrosomal autoantibodies in chronic hepatitis C virus infection and delta hepatitis]
Hepatitis, Autoimmune
[Spondyloenchondrodysplasia with immune dysregulation: a case report and literature review].
Hepatitis, Chronic
Absence of LKM-1 antibody reactivity in autoimmune and hepatitis-C-related chronic liver disease in Sweden. Swedish Internal Medicine Liver club.
Hepatitis, Chronic
Antibodies to liver/kidney microsome1 in chronic active hepatitis recognize specific forms of hepatic cytochrome P-450.
Hepatitis, Chronic
Autoimmune hepatitis type 2 and hepatitis C virus infection: study of HLA antigens.
Hepatitis, Chronic
Characterization of anti-liver kidney microsomal antibody in childhood autoimmune chronic active hepatitis: evidence for IgG1 subclass restriction, polyclonality and non cross-reactivity with hepatocyte surface antigens.
Hepatitis, Chronic
Characterization of the microsomal antigen related to a subclass of active chronic hepatitis.
Hepatitis, Chronic
Chronic active hepatitis associated with liver-kidney microsomal antibody of an autoimmune type. Two familial cases.
Hepatitis, Chronic
Chronic active hepatitis associated with vitiligo, nail dystrophy, alopecia and a new variant of LKM antibodies.
Hepatitis, Chronic
Clinical significance of the trimethadione tolerance test in chronic hepatitis: a useful indicator of hepatic drug metabolizing capacity.
Hepatitis, Chronic
Clonal analysis of liver-infiltrating T cells in patients with LKM-1 antibody-positive autoimmune chronic active hepatitis.
Hepatitis, Chronic
Detection of autoantibodies against M2, LKM-1, and SLA in liver diseases by standardized uniform ELISA-techniques.
Hepatitis, Chronic
Distinction between natural and pathological autoantibodies by immunoblotting and densitometric subtraction: liver-kidney microsomal antibody (LKM) positive sera identify multiple antigens in human liver tissue.
Hepatitis, Chronic
IgG subclass distribution of autoantibodies to glomerular basement membrane in Goodpasture's syndrome compared to other autoantibodies.
Hepatitis, Chronic
Immunoblotting as a confirmatory test for antimitochondrial antibodies in primary biliary cirrhosis.
Hepatitis, Chronic
Interferon and prednisone therapy in chronic hepatitis C with non-organ-specific antibodies.
Hepatitis, Chronic
Interferon and steroid treatment in patients with chronic hepatitis C and antinuclear or anti-liver-kidney microsomal antibodies.
Hepatitis, Chronic
Liver cell surface expression of the antigen reacting with liver-kidney microsomal antibody (LKM).
Hepatitis, Chronic
Low hepatitis C viremia levels in patients with anti-liver/kidney microsomal antibody type 1 positive chronic hepatitis.
Hepatitis, Chronic
Major antigen of liver kidney microsomal autoantibodies in idiopathic autoimmune hepatitis is cytochrome P450db1.
Hepatitis, Chronic
Non-organ specific autoantibodies associated with chronic C virus hepatitis.
Hepatitis, Chronic
Prevalence and significance of abdominal lymphadenopathy in patients with chronic liver disease: an ultrasound study.
Hepatitis, Chronic
[Autoantibodies in chronic hepatitis C. Markers of autoimmunity or non-specific events?]
Hepatitis, Chronic
[Chronic active hepatitis: recurrence after long-term immunosuppressive therapy in spite of normal liver histology]
Hepatitis, Chronic
[Chronic hepatitis: interest of a classification based on the presence or the absence of HBs Ag, smooth muscle antibody and microsomal antibody (author's transl)]
Hepatitis, Chronic
[Clinical and experimental histochemical studies on the activities of liver lysosomal enzymes and gamma-glutamyl transpeptidase (gamma-GTP) (author's transl)]
Hepatitis, Chronic
[Heterogeneity of antimicrosomal autoantibodies in chronic hepatitis C virus infection and delta hepatitis]
Hepatitis, Chronic
[Non-organ specific anticytoplasmic autoantibodies. Immunoserologic detection and diagnostic relevance]
Hepatitis, Chronic
[The assessment of liver microsomal oxidative capacity via caffeine and antipyrine elimination in patients with chronic active hepatitis: preliminary results]
Hepatitis, Chronic
[Tienilic acid-induced hepatitis associated with liver/kidney microsomal antibody (author's transl)]
Hepatomegaly
Age-related changes in the susceptibility to clofibric acid, a hypolipidemic agent, of male rat liver.
Hepatomegaly
Biochemical, morphological and flow-cytometric evaluation of the effects of hexachlorobenzene on rat liver.
Hepatomegaly
Characteristics and significance of D-tagatose-induced liver enlargement in rats: An interpretative review.
Hepatomegaly
Comparative study of four hypolipidaemic agents on the activity of drug-metabolizing enzymes in rat liver microsomes.
Hepatomegaly
Cytotoxicity and transcriptional activation of stress genes in human liver carcinoma (HepG2) cells exposed to iprodione.
Hepatomegaly
Effects of aging and phenobarbital on the rat liver microsomal drug-metabolizing system.
Hepatomegaly
Effects of chronic administration of bromazepam on its blood level profile and on the hepatic microsomal drug-metabolizing enzymes in the rat.
Hepatomegaly
Experimental studies on pharmacology, metabolism and toxicology with tiadenol-disulfoxide. Dissociation of lipid lowering effects and the induction of peroxisomal and microsomal drug-metabolizing enzymes.
Hepatomegaly
Hepatocellular hypertrophy and cell proliferation in Sprague-Dawley rats following dietary exposure to ammonium perfluorooctanoate occurs through increased activation of the xenosensor nuclear receptors PPAR? and CAR/PXR.
Hepatomegaly
Loss of tumor-promoting activity of unleaded gasoline in N-nitrosodiethylamine-initiated ovariectomized B6C3F1 mouse liver.
Hepatomegaly
Proceedings: Synthesis and metabolic stability of microsomal protein and enzymes metabolizing the hepatocarcinogen diethyl-nitrosamine during experimental hepatomegaly.
Hepatomegaly
Responses of the liver to perfluorinated fatty acids with different carbon chain length in male and female mice:in relation to induction of hepatomegaly, peroxisomal beta-oxidation and microsomal 1-acylglycerophosphocholine acyltransferase.
Hepatomegaly
Sex-related difference in the inductions by perfluoro-octanoic acid of peroxisomal beta-oxidation, microsomal 1-acylglycerophosphocholine acyltransferase and cytosolic long-chain acyl-CoA hydrolase in rat liver.
Hepatomegaly
The influence of Propionibacterium acnes (Corynebacterium parvum) fractions on immune response in vivo.
Hepatomegaly
The relationship among microsomal enzyme induction, liver weight, and histological change in cynomolgus monkey toxicology studies.
Hepatomegaly
Toxicological approach for elucidation of clobazam-induced hepatomegaly in male rats.
Hepatomegaly
Weight-of-evidence versus strength-of-evidence in toxicologic hazard identification: Di(2-ethylhexyl)phthalate (DEHP).
Hepatomegaly
[Changes in the hydroxylating function and structure of the hepatic endoplasmic reticulum of the rat as affected by long-term kordiamin administration]
Herpes Simplex
Altered kinetic properties of sialyl and galactosyl transferases associated with herpes simplex virus infection of GMK and BHK cells.
Herpes Simplex
Identification of replication-competent HSV-1 Cgal+ strain signaling targets in human hepatoma cells by functional organelle proteomics.
Herpes Simplex
Intracellular location, complex formation, and function of the transporter associated with antigen processing in yeast.
Herpes Simplex
Prevalence of antibodies to hepatitis C and herpes simplex virus type 1 is not increased in children with liver kidney microsomal type 1 autoimmune hepatitis.
Herpes Zoster
3-Hydroxy-3-methylglutaryl coenzyme A reductase activity in beef adrenal cortex.
Herpes Zoster
Circulating auto-antibodies against the zona pellucida and thyroid microsomal antigen in women with premature ovarian failure.
Herpes Zoster
Continuous adrenocorticotropin administration in hypopituitarism produces asynchronous increases of deoxycorticosterone and 11-deoxycortisol relative to other reduced zona fasciculata steroids.
Herpes Zoster
Dose-dependent actions of spironolactone on the inner and outer zones of the guinea pig adrenal cortex.
Herpes Zoster
Effects of age and adrenocorticotropin on microsomal enzymes in guinea pig adrenal inner and outer cortices.
Herpes Zoster
Effects of cadmium in vitro on microsomal steroid metabolism in the inner and outer zones of the guinea pig adrenal cortex.
Herpes Zoster
Effects of tocopherol depletion on the regional differences in adrenal microsomal lipid peroxidation and steroid metabolism.
Herpes Zoster
Functional differences in cholesterol ester hydrolase and acyl-coenzyme-A/cholesterol acyltransferase between the outer and inner zones of the guinea pig adrenal cortex.
Herpes Zoster
In vitro conversion of cholesterol into aldosterone and cortisol in different zones of the bovine adrenal cortex.
Herpes Zoster
Localization of cytochrome P-450-linked mixed function oxidase and steroid hydroxylations within zones of bovine adrenocortices.
Herpes Zoster
Regional distribution of microsomal drug and steroid metabolism in the guinea pig adrenal cortex.
Herpes Zoster
Zonal differences in adrenocortical lipid peroxidation: role of alpha-tocopherol.
Herpes Zoster
Zonation of the adrenal cortex. III. Distribution of cytochrome P-450 in the zona glomerulosa of the bovine adrenal cortex.
HIV Infections
Pharmacokinetic interaction of antimicrobial agents with levomethadon in drug-addicted AIDS patients.
Homozygous Familial Hypercholesterolemia
Case report: The efficacy and safety of lomitapide in a homozygous familial hypercholesterolemic child.
Homozygous Familial Hypercholesterolemia
Correction to: Lomitapide - a Microsomal Triglyceride Transfer Protein Inhibitor for Homozygous Familial Hypercholesterolemia.
Homozygous Familial Hypercholesterolemia
Critical review of non-statin treatments for dyslipoproteinemia.
Homozygous Familial Hypercholesterolemia
Dietary Intake during 56 Weeks of a Low-Fat Diet for Lomitapide Treatment in Japanese Patients with Homozygous Familial Hypercholesterolemia.
Homozygous Familial Hypercholesterolemia
Efficacy and Safety of Lomitapide in Hypercholesterolemia.
Homozygous Familial Hypercholesterolemia
Emerging low-density lipoprotein therapies: Microsomal triglyceride transfer protein inhibitors.
Homozygous Familial Hypercholesterolemia
Evaluation of the effects of the weak CYP3A inhibitors atorvastatin and ethinyl estradiol/norgestimate on lomitapide pharmacokinetics in healthy subjects.
Homozygous Familial Hypercholesterolemia
Homozygous Familial Hypercholesterolemia (HoFH) in Saudi Arabia and Two Cases of Lomitapide Use in a Real-World Setting.
Homozygous Familial Hypercholesterolemia
In vivo regulation of human mononuclear leukocyte 3-hydroxy-3-methylglutaryl coenzyme A reductase. Decreased enzyme catalytic efficiency in familial hypercholesterolemia.
Homozygous Familial Hypercholesterolemia
Inhibition of hepatic microsomal triglyceride transfer protein - a novel therapeutic option for treatment of homozygous familial hypercholesterolemia.
Homozygous Familial Hypercholesterolemia
Inhibition of microsomal triglyceride transfer protein in familial hypercholesterolemia.
Homozygous Familial Hypercholesterolemia
Lomitapide for the management of homozygous familial hypercholesterolemia.
Homozygous Familial Hypercholesterolemia
Lomitapide for the treatment of hypertriglyceridemia.
Homozygous Familial Hypercholesterolemia
Lomitapide-a Microsomal Triglyceride Transfer Protein Inhibitor for Homozygous Familial Hypercholesterolemia.
Homozygous Familial Hypercholesterolemia
Long-term clinical results of microsomal triglyceride transfer protein inhibitor use in a patient with homozygous familial hypercholesterolemia.
Homozygous Familial Hypercholesterolemia
Long-Term Efficacy and Safety of the Microsomal Triglyceride Transfer Protein Inhibitor Lomitapide in Patients With Homozygous Familial Hypercholesterolemia.
Homozygous Familial Hypercholesterolemia
LOWER, a registry of lomitapide-treated patients with homozygous familial hypercholesterolemia: Rationale and design.
Homozygous Familial Hypercholesterolemia
Management of familial hypercholesterolemia: a review of the recommendations from the national lipid association expert panel on familial hypercholesterolemia.
Homozygous Familial Hypercholesterolemia
Management of homozygous familial hypercholesterolaemia in two brothers.
Homozygous Familial Hypercholesterolemia
Management of homozygous familial hypercholesterolemia in real-world clinical practice: A report of 7 Italian patients treated in Rome with lomitapide and lipoprotein apheresis.
Homozygous Familial Hypercholesterolemia
Modern Management of Familial Hypercholesterolemia.
Homozygous Familial Hypercholesterolemia
MTP inhibitor decreases plasma cholesterol levels in LDL receptor-deficient WHHL rabbits by lowering the VLDL secretion.
Homozygous Familial Hypercholesterolemia
Review of the long-term safety of lomitapide: a microsomal triglycerides transfer protein inhibitor for treating homozygous familial hypercholesterolemia.
Homozygous Familial Hypercholesterolemia
Targeting microsomal triglyceride transfer protein and lipoprotein assembly to treat homozygous familial hypercholesterolemia.
Homozygous Familial Hypercholesterolemia
The Severe Hypercholesterolemia Phenotype: Clinical Diagnosis, Management, and Emerging Therapies.
Homozygous Familial Hypercholesterolemia
Therapeutic options for homozygous familial hypercholesterolemia: the role of Lomitapide.
Homozygous Familial Hypercholesterolemia
Treating homozygous familial hypercholesterolemia in a real-world setting: Experiences with lomitapide.
Homozygous Familial Hypercholesterolemia
Use of microsomal triglyceride transfer protein inhibitors in patients with homozygous familial hypercholesterolemia: translating clinical trial experience into clinical practice.
Homozygous Familial Hypercholesterolemia
What are we able to achieve today for our patients with homozygous familial hypercholesterolaemia, and what are the unmet needs?
Hookworm Infections
Hepatic microsomal cytochrome P450 system during experimental hookworm infection.
HTLV-I Infections
A high prevalence of human T-lymphotropic virus type I carriers in patients with antithyroid antibodies.
Hyperaldosteronism
Steroid 21-hydroxylase and 17 alpha-hydroxylase in microsomal fraction of functioning adrenocortical tumors.
Hypercholesterolemia
Competitive inhibition of hepatic sterol 27-hydroxylase by sitosterol: decreased activity in sitosterolemia.
Hypercholesterolemia
Development of MEPS-UHPLC-MS/MS multistatin methods for clinical analysis.
Hypercholesterolemia
Effect of dietary antioxidants on the susceptibility to hepatic microsomal lipid peroxidation in the rat.
Hypercholesterolemia
Effects of hypercholesterolemia on the microsomal membrane fluidity of intimal-medial versus medial layers of swine aorta: implications for the pathogenesis of vasospasm.
Hypercholesterolemia
Expression of mRNA of apolipoprotein E, apolipoprotein A-IV, and matricellular proteins in the myocardium and intensity of fibroplastic processes during experimental hypercholesterolemia.
Hypercholesterolemia
Hepatic tissue sterol regulatory element binding protein 2 and low-density lipoprotein receptor in nephrotic syndrome.
Hypercholesterolemia
Hypocholesterolemic action of pre-germinated brown rice in hepatoma-bearing rats.
Hypercholesterolemia
Inhibition of microsomal triglyceride transfer protein alone or with ezetimibe in patients with moderate hypercholesterolemia.
Hypercholesterolemia
Inhibitors of acyl-CoA:cholesterol O-acyltransferase. synthesis and pharmacological activity of (+/-)-2-dodecyl-alpha-phenyl-N-(2,4,6-trimethoxyphenyl)-2H-tetrazole-5- acetamide and structurally related tetrazole amide derivatives.
Hypercholesterolemia
Is there a role for the adrenals in the development of hypercholesterolemia in Zucker fatty rats?
Hypercholesterolemia
Lomitapide, a microsomal triglyceride transfer protein inhibitor for the treatment of hypercholesterolemia.
Hypercholesterolemia
Microsomal transfer protein (MTP) inhibition-a novel approach to the treatment of homozygous hypercholesterolemia.
Hypercholesterolemia
miR33 inhibition overcomes deleterious effects of diabetes mellitus on atherosclerosis plaque regression in mice.
Hypercholesterolemia
Pharmacokinetic interactions of the microsomal triglyceride transfer protein inhibitor, lomitapide, with drugs commonly used in the management of hypercholesterolemia.
Hypercholesterolemia
Severe hypertriglyceridemia with pancreatitis: thirteen years' treatment with lomitapide.
Hypercholesterolemia
The effect of pravastatin on hepatic 3-hydroxy-3-methylglutaryl CoA reductase obtained from poloxamer 407-induced hyperlipidemic rats.
Hypercholesterolemia
[Formation of mevalonic acid, sterols and bile acids from [1-14C]acetyl-CoA and [2-14C]malonyl-CoA in the liver of rabbits with experimental hypercholesterolemia]
Hyperglycemia
Effect of diabetes on enzymes involved in rat hepatic corticosterone production.
Hyperglycemia
Effects of Maternal Flaxseed Supplementation on Female Offspring of Diabetic Rats in Serum Concentration of Glucose, Insulin, and Thyroid Hormones.
Hyperglycemia
JTT-130, a novel intestine-specific inhibitor of microsomal triglyceride transfer protein, improves hyperglycemia and dyslipidemia independent of suppression of food intake in diabetic rats.
Hyperglycemia
Permanent diabetes without serological evidence of autoimmunity after transient neonatal diabetes.
Hyperglycemia
Peroxyvanadium compounds inhibit glucose-6-phosphatase activity and glucagon-stimulated hepatic glucose output in the rat in vivo.
Hyperglycemia
Separate influences of insulin and hyperglycemia on hepatic drug metabolism in mice with genetic and chemically induced diabetes mellitus.
Hyperhomocysteinemia
Hematinic deficiencies and hyperhomocysteinemia in gastric parietal cell antibody-positive or gastric and thyroid autoantibodies-negative atrophic glossitis patients.
Hyperinsulinism
Chronic hyperinsulinemia inhibits platelet-activating factor (PAF) biosynthesis in the rat kidney.
Hyperinsulinism
Comparison of the effect of hyperinsulinemia on acyl-CoA:cholesterol acyltransferase activity in the liver and intestine of the rat.
Hyperinsulinism
Increased fetal insulin receptors and changes in membrane fluidity and lipid composition.
Hyperinsulinism
Insulin degradation. XVIII. On the regulation of glutathione-insulin transhydrogenase in the hyperglycemic obese (ob/ob) mouse.
Hyperinsulinism
Visceral obesity and hyperinsulinemia modulate the impact of the microsomal triglyceride transfer protein -493G/T polymorphism on plasma lipoprotein levels in men.
Hyperlipidemias
A wild-type mouse-based model for the regression of inflammation in atherosclerosis.
Hyperlipidemias
Drug evaluation: The MTP inhibitor JTT-130 as a potential treatment for hyperlipidemia.
Hyperlipidemias
Effect of rat serum lipoproteins on mRNA levels and amiodarone metabolism by cultured primary rat hepatocytes.
Hyperlipidemias
Effects of poloxamer 407-induced hyperlipidemia on the pharmacokinetics of carbamazepine and its 10,11-epoxide metabolite in rats: Impact of decreased expression of both CYP3A1/2 and microsomal epoxide hydrolase.
Hyperlipidemias
Enhanced expression of hepatic acyl-coenzyme A synthetase and microsomal triglyceride transfer protein messenger RNAs in the obese and hypertriglyceridemic rat with visceral fat accumulation.
Hyperlipidemias
Familial hypobetalipoproteinemia due to apolipoprotein B R463W mutation causes intestinal fat accumulation and low postprandial lipemia.
Hyperlipidemias
Hepatic expression of microsomal triglyceride transfer protein and in vivo secretion of triglyceride-rich lipoproteins are increased in obese diabetic mice.
Hyperlipidemias
Hepatic triacylglycerol synthesizing activity during progression of alcoholic liver injury in the baboon.
Hyperlipidemias
MicroRNA-30c reduces hyperlipidemia and atherosclerosis in mice by decreasing lipid synthesis and lipoprotein secretion.
Hyperlipidemias
Microsomal ethanol-oxidizing system (MEOS): the first 30 years (1968-1998)--a review.
Hyperlipidemias
Novel Abetalipoproteinemia Missense Mutation Highlights the Importance of the N-Terminal ?-Barrel in Microsomal Triglyceride Transfer Protein Function.
Hyperlipidemias
Postprandial hypertriglyceridemia and cardiovascular disease: current and future therapies.
Hyperlipidemias
Reversal of hyperlipidemia with a genetic switch favorably affects the content and inflammatory state of macrophages in atherosclerotic plaques.
Hyperlipidemias
Small RNA overcomes the challenges of therapeutic targeting of microsomal triglyceride transfer protein.
Hyperlipidemias
Supplementation of all trans retinoic acid ameliorates ethanol-induced endoplasmic reticulum stress.
Hyperlipidemias
The effect of experimental hyperlipidemia on the stereoselective tissue distribution, lipoprotein association and microsomal metabolism of (+/-)-halofantrine.
Hyperlipidemias
The environmental and genetic evidence for the association of hyperlipidemia and hypertension.
Hyperlipoproteinemia Type II
A functional polymorphism in the promoter region of the microsomal triglyceride transfer protein (MTP -493G/T) influences lipoprotein phenotype in familial hypercholesterolemia.
Hyperlipoproteinemia Type II
Effect of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor pravastatin on urinary 6 beta-hydroxycortisol excretion: a preliminary study.
Hyperlipoproteinemia Type II
Inhibition of microsomal triglyceride transfer protein in familial hypercholesterolemia.
Hyperlipoproteinemia Type II
Looking into the crystal ball-upcoming drugs for dyslipidemia.
Hyperlipoproteinemia Type II
Microsomal Transfer Protein Inhibitors, New Approach for Treatment of Familial Hypercholesterolemia, Review of the Literature, Original Findings and Clinical Significance.
Hyperlipoproteinemia Type II
Recent developments in the treatment of familial hypercholesterolemia: a review of several new drug classes.
Hyperlipoproteinemia Type II
The role of microsomal triglyceride transfer protein inhibitors in the treatment of patients with familial hypercholesterolemia: risks, benefits, and management.
Hyperprolactinemia
New evidence for a direct effect of prolactin on rat adrenal steroidogenesis.
Hyperprolactinemia
The effects of prolactin on rat testicular steroidogenic enzyme activities.
Hypersensitivity
A microsomal fraction of Cryptococcus neoformans induces lymphocyte blastogenesis in infected guinea pigs.
Hypersensitivity
Aspirin-induced asthma. Hypersensitivity to fenoprofen and ibuprofen in relation to their inhibitory action on prostaglandin generation by different microsomal enzymic preparations.
Hypersensitivity
Autoantibodies in Estonia and Sweden, populations with different responses to allergens.
Hypersensitivity
Detection of an autoantibody directed against human liver microsomal protein in a patient with carbamazepine hypersensitivity.
Hypersensitivity
Differential selectivity in carbamazepine-induced inactivation of cytochrome P450 enzymes in rat and human liver.
Hypersensitivity
Enflurane metabolism produces covalently bound liver adducts recognized by antibodies from patients with halothane hepatitis.
Hypersensitivity
Genetic analysis of microsomal epoxide hydrolase in patients with carbamazepine hypersensitivity.
Hypersensitivity
Human anti-endoplasmic reticulum autoantibodies produced in aromatic anticonvulsant hypersensitivity reactions recognise rodent CYP3A proteins and a similarly regulated human P450 enzyme(s)
Hypersensitivity
Kinetic parameters of lymphocyte microsomal epoxide hydrolase in carbamazepine hypersensitive patients. Assessment by radiometric HPLC.
Hypersensitivity
Nonenzymatic formation of a novel hydroxylated sulfamethoxazole derivative in human liver microsomes: implications for bioanalysis of sulfamethoxazole metabolites.
Hypersensitivity
Patients with delayed-onset sulfonamide hypersensitivity reactions have antibodies recognizing endoplasmic reticulum luminal proteins.
Hypertension
Age-related depletion of linoleic acid desaturation in liver microsomes from young spontaneously hypertensive rats.
Hypertension
Changes in angiotensin receptors expression play a pivotal role in the renal damage observed in spontaneously hypertensive rats.
Hypertension
Clinical features of end-stage renal failure in patients with essential hypertension.
Hypertension
Combined homozygous 21 hydroxylase with heterozygous P450 oxidoreductase mutation in a Saudi boy presented with hypertension.
Hypertension
Decreased myocardial Na+K+ATPase activity in rats with reduced renal mass-saline hypertension.
Hypertension
Demonstration of a ouabainlike plasma compound in hypertension prone and hypertension resistant rats.
Hypertension
Effect of sucrose addition to drinking water, that induces hypertension in the rats, on liver microsomal Delta9 and Delta5-desaturase activities.
Hypertension
Experimental and/or genetically controlled alterations of the renal microsomal cytochrome P450 epoxygenase induce hypertension in rats fed a high salt diet.
Hypertension
Liver microsomal membrane fluidity and microsomal desaturase activities in adult spontaneously hypertensive rats.
Hypertension
Membrane abnormalities occur in vascular smooth muscle but not in non-vascular smooth muscle from rats with deoxycorticosterone-salt induced hypertension.
Hypertension
Microsomal prostaglandin synthase-1-derived prostaglandin E2 protects against angiotensin II-induced hypertension via inhibition of oxidative stress.
Hypertension
Missense Genetic Polymorphisms of Microsomal (EPHX1) and Soluble Epoxide Hydrolase (EPHX2) and Their Relation to the Risk of Large Artery Atherosclerotic Ischemic Stroke in a Turkish Population.
Hypertension
Modifications of flexible nonyl chain and nucleobase head group of (+)-erythro-9-(2's-hydroxy-3's-nonyl)adenine [(+)-EHNA] as adenosine deaminase inhibitors.
Hypertension
Myocardial Na,K-ATPase activity in rats with steroid and spontaneous hypertension.
Hypertension
Reversal of one-kidney, one-clip hypertension in rats. Effects on myocardial Na+, K(+)-ATPase, arterial Na(+)-K+ pump, arterial membrane potential, and plasma Na(+)-K+ pump inhibitory activity.
Hypertension
Role of cellular sodium and calcium metabolism in the pathogenesis of essential hypertension.
Hypertension
Single-Nucleotide Polymorphisms (SNPs) Both Associated with Hypertension and Contributing to Accelerated-Senescence Traits in OXYS Rats.
Hypertension
Tempol, an antioxidant, restores endothelium-derived hyperpolarizing factor-mediated vasodilation during hypertension.
Hypertension
The environmental and genetic evidence for the association of hyperlipidemia and hypertension.
Hypertension
The prevalence of autoantibodies during third-trimester pregnancy complicated by hypertension or idiopathic fetal growth retardation.
Hypertension
[Characteristics of calcium and sodium transport in the synaptosomes and subsynaptosomal structures of the brain of spontaneously hypertensive rats]
Hypertension, Portal
Does protracted antiviral therapy impact on HCV-related liver cirrhosis progression?
Hypertension, Portal
Leopard-like retinopathy and severe early-onset portal hypertension expand the phenotype of KARS1-related syndrome: a case report.
Hypertension, Portal
Lipid changes in hepatic microsomes and its relationship to P-nitrophenol glucuronidation in an experimental model of portal hypertension.
Hypertension, Portal
Reversibility of secondary biliary fibrosis by biliodigestive anastomosis in the rat.
Hypertension, Portal
Structure-function relationship in secondary biliary cirrhosis in the rat. Stereologic and hemodynamic characterization of a model.
Hypertension, Portal
Ursodeoxycholate has no beneficial effect on liver function or histology in biliary cirrhosis in the rat.
Hypertension, Pulmonary
Can microsomal RNA be a biomarker in pulmonary hypertension secondary to bronchopulmonary dysplasia?
Hyperthyroidism
Altered plasma half-lives of antipyrine, propylthiouracil, and methimazole in thyroid dysfunction.
Hyperthyroidism
Amiodarone-induced thyroid dysfunction in a tertiary center in south Brazil.
Hyperthyroidism
Antithyroid microsomal autoantibodies and HLA-DR5 are associated with postpartum thyroid dysfunction: evidence supporting an autoimmune pathogenesis.
Hyperthyroidism
Change of circulating thyroid autoantibody titers in Graves' hyperthyroidism after antithyroid drugs therapy.
Hyperthyroidism
Chemiluminescent and respiratory responses related to thyroid hormone-induced liver oxidative stress.
Hyperthyroidism
Comparison of covalent binding from halothane metabolism in hepatic microsomes from phenobarbital-induced and hyperthyroid rats.
Hyperthyroidism
Correlation of orbital computed tomography and antibodies in patients with hyperthyroid Graves' disease.
Hyperthyroidism
Effect of hyperthyroidism on lipogenesis in brown adipose tissue of young rats.
Hyperthyroidism
Effect of hyperthyroidism on the in vitro metabolism and covalent binding of 1,1-dichloroethylene in rat liver microsomes.
Hyperthyroidism
Effect of thyroid dysfunction upon phospholipid composition and CDP-choline incorporation in mitochondria and microsomal fraction isolated from liver and brain of suckling rats.
Hyperthyroidism
Effect of thyroid hormones on microsomal fatty acid chain elongation synthesis in rat liver.
Hyperthyroidism
Effect of thyrotropin-releasing hormone on serum thyroid hormones: a study in the patients with untreated and treated Graves' disease and subacute thyroiditis.
Hyperthyroidism
Effects of neonatal hyperthyroidism on activity of cyclic AMP-dependent microsomal protein kinase.
Hyperthyroidism
Enhancement of lindane-induced liver oxidative stress and hepatotoxicity by thyroid hormone is reduced by gadolinium chloride.
Hyperthyroidism
Expression of the microsomal antigen on the surface of continuously cultured rat thyroid cells is modulated by thyrotropin.
Hyperthyroidism
Fatty-acid desaturation and microsomal lipid fatty-acid composition in experimental hyperthyroidism.
Hyperthyroidism
Hepatic conversion of amino-nitrogen to urea in thyroid diseases. II. A study in hyperthyroid patients.
Hyperthyroidism
Hepatic microsomal ethanol-oxidizing system (MEOS): increased activity following propylthiouracil administration.
Hyperthyroidism
Hyperthyroidism following primary hypothyroidism in association with polyendocrine autoimmunity.
Hyperthyroidism
Induction of microsomal 1-acylglycerophosphocholine acyltransferase by peroxisome proliferators in rat kidney; co-induction with peroxisomal beta-oxidation.
Hyperthyroidism
Influence of hyperthyroidism on the activity of liver nitric oxide synthase in the rat.
Hyperthyroidism
Influence of hyperthyroidism on the uptake and binding of calcium by cardiac microsomal fractions and on mitochondrial structure.
Hyperthyroidism
Influence of hypo- and hyperthyroidism on rat liver glycerophospholipid metabolism.
Hyperthyroidism
Insulin-dependent diabetes mellitus in southern Chinese children: an overview.
Hyperthyroidism
Iodide induces thyroid autoimmunity in patients with endemic goitre: a randomised, double-blind, placebo-controlled trial.
Hyperthyroidism
Lipid composition of liver mitochondria and microsomes in hyperthyroid rats.
Hyperthyroidism
Liver microsomal parameters related to oxidative stress and antioxidant systems in hyperthyroid rats subjected to acute lindane treatment.
Hyperthyroidism
Manifestation of Hashimoto's encephalopathy years before onset of thyroid disease.
Hyperthyroidism
Organ-specific autoimmunity and genetic predisposition in interferon-treated HCV-related chronic hepatitis patients.
Hyperthyroidism
Patients with endocrine ophthalmopathy not associated with overt thyroid disease have multiple thyroid immunological abnormalities.
Hyperthyroidism
Prognostic significance of thyroid antibodies in hyperthyroid patients treated with antithyroid drugs.
Hyperthyroidism
Randomized, double blind, placebo-controlled trial of low dose iodide in endemic goiter.
Hyperthyroidism
Role of thyroid state on induction by ciprofibrate of laurate hydroxylase and peroxisomal enzymes in rat liver microsomes.
Hyperthyroidism
Superoxide radical generation, NADPH oxidase activity, and cytochrome P-450 content of rat liver microsomal fractions in an experimental hyperthyroid state: relation to lipid peroxidation.
Hyperthyroidism
The changes of serum titers of thyroid antibodies in patients of Graves' disease with hyperthyroidism after treatments with antithyroid drugs.
Hyperthyroidism
The effect of dithiotreitol on thyroid peroxidase and microsomal antigen epitopes recognized by auto and monoclonal antibodies.
Hyperthyroidism
The effect of treatment with levothyroxine or iodine on thyroid size and thyroid growth stimulating immunoglobulins in endemic goitre patients.
Hyperthyroidism
The relationship between autoimmune thyroid disease and iodine intake: a review.
Hyperthyroidism
The significance of antithyroglobulin and antithyroidal microsomal antibodies in patients with hyperthyroidism due to Graves' disease treated with antithyroidal drugs.
Hyperthyroidism
Thioredoxin and glutaredoxin systems of rat liver cytosol are not influenced by thyroid dysfunction.
Hyperthyroidism
Thyroid disease is associated with an increased risk of breast cancer: a systematic review and meta-analysis.
Hyperthyroidism
Thyroid function and autoimmune manifestations in insulin-dependent diabetes mellitus during and after pregnancy.
Hyperthyroidism
Thyroid hormone-induced changes in the hepatic monooxygenase system, heme oxygenase activity and epoxide hydrolase activity in adult male, female and immature rats.
Hyperthyroidism
[Autoimmune thyroid pathology. Study and follow-up of pediatric case reports]
Hyperthyroidism
[Comparison of thiamazole pharmacokinetics in healthy individuals and patients with hyperthyroidism]
Hyperthyroidism
[Cytologic differentiation between the autonomous and autoimmune type of diffuse hyperthyroid goiter: correlation with TSH receptor antibodies, microsomal antibodies and infiltrative ophthalmopathy]
Hyperthyroidism
[Phenobarbital-induced changes in enzyme activities of the microsomal oxidative system in the liver of normal rats of different ages and in rats with hyperthyroidism]
Hyperthyroidism
[Serum levels of interleukin 6 (IL-6) and soluble IL-6 receptor (sIL-6R) in children and adolescents with Graves-Basedow disease]
Hypertriglyceridemia
Augmentation of Ca2+-induced microsomal triglyceride transfer protein activity by glucose supply enhances hypertriglyceridemia in vivo.
Hypertriglyceridemia
HMG-CoA reductase activity in the liver of rats with hereditary hypertriglyceridemia: effect of dietary fish oil.
Hypertriglyceridemia
Severe hypertriglyceridemia with pancreatitis: thirteen years' treatment with lomitapide.
Hypertriglyceridemia
The possible role of Ca2+ on the activation of microsomal triglyceride transfer protein in rat hepatocytes.
Hypertrophy, Right Ventricular
The distribution of microsomal (Na+, K+)-ATPase in the rat heart and the effects of induced right ventricular hypertrophy and feeding with digitalis, sodium, and potassium.
Hypertrophy, Right Ventricular
Time-dependent alterations of myocardial microsomal yield and calcium accumulation in experimentally-induced right ventricular hypertrophy and failure.
Hypoalphalipoproteinemias
Microsomal enzyme inducers raise plasma high-density lipoprotein cholesterol levels in healthy control subjects but not in patients with primary hypoalphalipoproteinemia.
Hypobetalipoproteinemias
Hypobetalipoproteinemia and abetalipoproteinemia: liver disease and cardiovascular disease.
Hypobetalipoproteinemias
Insights from human congenital disorders of intestinal lipid metabolism.
Hypobetalipoproteinemias
Recent progress in understanding protein and lipid factors affecting hepatic VLDL assembly and secretion.
Hypobetalipoproteinemias
Structure-function analyses of microsomal triglyceride transfer protein missense mutations in abetalipoproteinemia and hypobetalipoproteinemia subjects.
Hypobetalipoproteinemias
The genetic basis of primary disorders of intestinal fat transport.
Hypoglycemia
Effect of hypoglycemia on the brain free fatty acid level and the uptake of fatty acids by phospholipids.
Hypoglycemia
Mitochondrial 2,4-dienoyl-CoA reductase deficiency in mice results in severe hypoglycemia with stress intolerance and unimpaired ketogenesis.
Hypoglycemia
[ATPase activity of rat brain microsomal and synaptosomal fractions in insulin hypoglycemia and its treatment with glucose]
Hypokinesia
[Enzyme system of initiation and protection against lipid peroxidation in the liver and blood of rats with hypokinesia]
Hypokinesia
[The state of the monooxygenase enzymatic system of the rat liver in hypokinesia]
Hypopituitarism
Continuous adrenocorticotropin administration in hypopituitarism produces asynchronous increases of deoxycorticosterone and 11-deoxycortisol relative to other reduced zona fasciculata steroids.
Hypopituitarism
Low sodium intake enhances sensitivity of 11-deoxycortisol and deoxycorticosterone to ACTH in ACTH-suppressed normal subjects.
Hypopituitarism
Organ- and non-organ-specific auto-antibodies in children with hypopituitarism on growth hormone therapy.
Hypoprothrombinemias
Depression of liver microsomal vitamin K epoxide reductase activity associated with antibiotic-induced coagulopathy.
Hypothyroidism
A case of a false-positive anti-myeloperoxidase antibody ELISA in a patient with hypothyroidism.
Hypothyroidism
A case of acetohexamide-induced hypoglycemia: the influence of hypothyroidism on the metabolism of acetohexamide.
Hypothyroidism
Altered plasma half-lives of antipyrine, propylthiouracil, and methimazole in thyroid dysfunction.
Hypothyroidism
Amnesic syndrome with bilateral mesial temporal lobe involvement in Hashimoto's encephalopathy.
Hypothyroidism
Association between thyroid microsomal antibodies of subclass IgG-1 and hypothyroidism in autoimmune postpartum thyroiditis.
Hypothyroidism
Autoimmune endocrine disease induced by recombinant interferon-alpha therapy for chronic active type C hepatitis.
Hypothyroidism
Autoimmune thyroid phenomena are not evidence for human lymphocyte antigen-genetic heterogeneity in insulin-dependent diabetes.
Hypothyroidism
Comparison of triacylglycerol synthesis in rat brown and white adipocytes. Effects of hypothyroidism and streptozotocin-diabetes on enzyme activities and metabolic fluxes.
Hypothyroidism
Development of postpartum spontaneously resolving transient Graves' hyperthyroidism followed immediately by transient hypothyroidism.
Hypothyroidism
Discordant changes in serum anti-TSH receptor antibody and antithyroid microsomal antibody during pregnancy in autoimmune thyroid diseases.
Hypothyroidism
Effect of neonatal hypothyroidism on the kinetic properties of Na+, K+ -ATPase from rat brain microsomes.
Hypothyroidism
Effect of thyroid dysfunction upon phospholipid composition and CDP-choline incorporation in mitochondria and microsomal fraction isolated from liver and brain of suckling rats.
Hypothyroidism
Effects of hypothyroidism and undernourishment on nuclear-cytoplasmic transport "in vitro" of cerebral RNA.
Hypothyroidism
Expression of the microsomal antigen on the surface of continuously cultured rat thyroid cells is modulated by thyrotropin.
Hypothyroidism
Fatty acid desaturation and microsomal lipid fatty acid composition in experimental hypothyroidism.
Hypothyroidism
IgG subclass distribution and relative functional affinity of thyroid microsomal antibodies in postpartum thyroiditis.
Hypothyroidism
Influence of hypo- and hyperthyroidism on rat liver glycerophospholipid metabolism.
Hypothyroidism
Insulin-dependent diabetes mellitus in southern Chinese children: an overview.
Hypothyroidism
Isolated right ventricular cardiomyopathy with autoimmune hypothyroidism: a rare association in an adolescent.
Hypothyroidism
Macroamylasemia attributable to gluten-related amylase autoantibodies: a case report.
Hypothyroidism
Measurement and clinical significance of thyroid microsomal and thyroglobulin antibodies by enzyme-linked immunosorbent assay.
Hypothyroidism
Mixed connective tissue disease associated with idiopathic portal hypertension and chronic thyroiditis.
Hypothyroidism
Natural history of thyroid function in diabetics with impaired thyroid reserve: a four year controlled study.
Hypothyroidism
Organ-specific autoimmunity and genetic predisposition in interferon-treated HCV-related chronic hepatitis patients.
Hypothyroidism
Patients with endocrine ophthalmopathy not associated with overt thyroid disease have multiple thyroid immunological abnormalities.
Hypothyroidism
Prediction of hypothyroidism after hemithyroidectomy: a biochemical and pathological analysis.
Hypothyroidism
Prevalence and relevance of thyroid dysfunction in 1922 cholesterol screening participants.
Hypothyroidism
Prevalence of abnormal thyrotropin concentrations measured by a sensitive assay in patients with type 2 diabetes mellitus.
Hypothyroidism
Recovery of the thyroid function in patients with atrophic hypothyroidism and blocking type TSH binding inhibitor immunoglobulin.
Hypothyroidism
Recovery of thyroid function with a decreased titre of antimicrosomal antibody in a hypothyroid man with Hashimoto's thyroiditis.
Hypothyroidism
Role of thyroid state on induction by ciprofibrate of laurate hydroxylase and peroxisomal enzymes in rat liver microsomes.
Hypothyroidism
Serum thyroid autoantibodies as a risk factor for development of hypothyroidism after radioactive iodine therapy for single thyroid 'hot' nodule.
Hypothyroidism
Spectrum of thyroid function in patient's remaining in remission after antithyroid drug therapy for thyrotoxicosis.
Hypothyroidism
The incidence of occult thyroid disease associated with thyroid antibodies identified on routine autoantibody screening.
Hypothyroidism
The influence of fasting and the thyroid state on the activity of thyroxine 5'-monodeiodinase in rat liver: a kinetic analysis of microsomal formation of triiodothyronine from thyroxine.
Hypothyroidism
Thyroid control over biomembranes: VI. Lipids in liver mitochondria and microsomes of hypothyroid rats.
Hypothyroidism
Thyroid disease and other autoimmune phenomena in a family study of primary Sjögren's syndrome.
Hypothyroidism
Thyroid disease is associated with an increased risk of breast cancer: a systematic review and meta-analysis.
Hypothyroidism
Transient postpartum hypothyroidism: fourteen cases with autoimmune thyroiditis.
Hypothyroidism
[A case of Hashimoto's encephalopathy with a relapsing course related to menstrual cycle]
Hypothyroidism
[Antithyroid antibodies. Prevalence in primary hypothyroidism in Central Tunisia]
Hypothyroidism
[Autoimmune haemolytic anaemia, thrombocytopenia and thyroiditis: an immunopathological triad (author's transl)]
Hypothyroidism
[Diabetes mellitus type I, thyroid gland autoimmunity, thyroid gland function and HLA status]
Hypothyroidism
[Occurrence of TSH receptor antibodies and thyroid microsomal antibodies in Graves-Basedow disease]
Hypothyroidism
[Profile of autoimmune antibodies in idiopathic hypothyroidism and hypothyroidism following radio-iodine treatment in Basedow's disease: comparison with a group of normal subjects from the female population of Switzerland]
Hypoxia-Ischemia, Brain
Cerebral hypoxia-ischemia increases microsomal iron in newborn piglets.
Ichthyosis
Early diagnosis of recessive X-linked ichthyosis: elevation of cholesterol sulfate levels in placental sulfatase deficiency before the onset of skin symptoms.
Ichthyosis
Isolation and characterization of a steroid sulfatase cDNA clone: genomic deletions in patients with X-chromosome-linked ichthyosis.
Ichthyosis
Role of cholesterol sulfate in epidermal structure and function: lessons from X-linked ichthyosis.
Ichthyosis
Steroid sulfatase = aryl sulfatase C? Chromatographic and electrophoretic properties in extracts from placental microsomes and skin fibroblasts.
Ichthyosis
Stratum corneum lipids in disorders of cornification: increased cholesterol sulfate content of stratum corneum in recessive x-linked ichthyosis.
Immune System Diseases
Microsomal triglyceride transfer protein in plasma and cellular lipid metabolism.
Immune System Diseases
[Fatal bleeding complications caused by Evans syndrome (autoimmune thrombocytopenia and hemolytic anemia) and type II autoimmune hepatitis in a 56-year-old patient]
Infections
A polymorphism in the microsomal triglyceride transfer protein can predict the response to antiviral therapy in Egyptian patients with chronic hepatitis C virus genotype 4 infection.
Infections
A study of hepatic mitochondrial respiration and microsomal cytochrome P450 content in mice infected with the liver fluke Fasciola hepatica.
Infections
Alterations of hepatic microsomal enzymes in the early phase of murine schistosomiasis.
Infections
Altered hepatic microsomal drug-metabolizing enzyme activity resulting from experimental infection of rats with Trypanosoma b. brucei.
Infections
Anti-rat liver microsomal and cytosolic antibodies in hepatitis C virus infection.
Infections
Antihepatotoxic properties of uridine-diphosphoglucose in liver fluke infection. Experimental fascioliasis in the rat.
Infections
Autoantibodies against glucuronosyltransferases differ between viral hepatitis and autoimmune hepatitis.
Infections
Autoantibody appearance in cytomegalovirus-infected liver transplant recipients: correlation with antigenemia.
Infections
Autoantibody prevalence in children with liver disease due to chronic hepatitis C virus (HCV) infection.
Infections
Autoimmunity and extrahepatic manifestations in treatment-naïve children with chronic hepatitis C virus infection.
Infections
Chagas' disease: a clinical, parasitological, immunological, and pathological study in rabbits.
Infections
Characterization of anti liver kidney microsomal antibody associated with chronic HDV infection by immunoblotting.
Infections
Comparative Subcellular Proteomics Analysis of Susceptible and Near-isogenic Resistant Bombyx mori (Lepidoptera) Larval Midgut Response to BmNPV infection.
Infections
Cytochrome P4502D6(193-212): a new immunodominant epitope and target of virus/self cross-reactivity in liver kidney microsomal autoantibody type 1-positive liver disease.
Infections
Decrease in hepatic microsomal UDP-glucuronosyl-transferase activity in rats and cattle with fascioliasis: impaired in vitro glucuronidation of oxyclozanide.
Infections
Demonstration of species-specific and cross-reactive components of the adult microsomal antigens from Schistosoma mansoni and S. japonicum (MAMA and JAMA).
Infections
Different levels of Schistosoma mansoni infection increased the mutagenicity of benzo(a)pyrene, the activity of aryl hydrocarbon hydroxylase and the formation of hepatic microsomal hydrogen peroxide.
Infections
Differential expression and regulation of microsomal prostaglandin E(2) synthase in human fetal membranes and placenta with infection and in cultured trophoblast cells.
Infections
Effect of experimental fasciolosis on antipyrine metabolism and clearance in water buffaloes.
Infections
Effect of malaria infection and endotoxin-induced fever on phenacetin O-deethylation by rat liver microsomes.
Infections
Effect of murine schistosomiasis on hepatic cytochrome P-450 and microsomal protein.
Infections
Effect of Plasmodium berghei infection and chloroquine on the hepatic drug metabolizing system of mice.
Infections
Effect of Plasmodium yoelii nigeriensis infection and chloroquine on the hepatic mixed function oxidase system of mice.
Infections
Effect of praziquantel treatment on the activities of some liver microsomal enzymes in mice infected with Schistosoma mansoni.
Infections
Effect of Schistosoma mansoni infection on the hepatic drug-metabolizing capacity of mice.
Infections
Enhanced metabolic activation of chemical hepatocarcinogens in woodchucks infected with hepatitis B virus.
Infections
Establishment of a novel radioligand assay using eukaryotically expressed cytochrome P4502D6 for the measurement of liver kidney microsomal type 1 antibody in patients with autoimmune hepatitis and hepatitis C virus infection.
Infections
Evidence of CD1d pathway of lipid antigen presentation in mouse primary lung epithelial cells and its up-regulation upon Mycobacterium bovis BCG infection.
Infections
Experimental ovine fasciolosis: antipyrine clearance as indicator of liver damage.
Infections
Expression of COX-2, mPGE-synthase1, MDR-1 (P-gp), and Bcl-xL: a molecular pathway of H pylori-related gastric carcinogenesis.
Infections
Falcipain Inhibitors Based on the Natural Product Gallinamide A Are Potent in Vitro and in Vivo Antimalarials.
Infections
Hepatic cytochrome P-450 system in experimental hepatosplenic schistosomiasis. Presence of an artifact in spectrophotometric analysis.
Infections
Hepatic microsomal alterations during Dipetalonema viteae infection in Mastomys natalensis.
Infections
Hepatic microsomal cytochrome P450 system during experimental hookworm infection.
Infections
Hepatic microsomal enzymes in S. mansoni infected mice: II. Effect of duration of infection and lindane administration on aminopyrine demethylase and aniline hydroxylase.
Infections
Hepatic microsomal enzymes in Schistosoma mansoni-infected mice: I. Effect of duration of infection and lindane administration on dimethylnitrosamine demethylases.
Infections
Hepatic microsomal protein and cytochrome P-450 in BALB/c mice infected with Leishmania.
Infections
Heterogeneity of liver-kidney microsomal autoantibodies in chronic hepatitis C and D virus infection.
Infections
Heterogeneity of liver/kidney microsomal antibody type 1 in autoimmune hepatitis and hepatitis C virus related liver disease.
Infections
Human papillomavirus 13 in a Mexican Mayan community with multifocal epithelial hyperplasia: could saliva be involved in household transmission?
Infections
Identification of replication-competent HSV-1 Cgal+ strain signaling targets in human hepatoma cells by functional organelle proteomics.
Infections
Improved expression and characterization of Ca2+-ATPase and phospholamban in High-Five cells.
Infections
In vitro determination of carcinogenicity of sixty-four compounds using a bovine papillomavirus DNA-carrying C3H/10T(1/2) cell line.
Infections
Infection (Actinobacillus pleuropneumoniae)-mediated suppression of oxidative hepatic drug metabolism and cytochrome P4503A mRNA levels in pigs.
Infections
Influence of Vesicular-Arbuscular Mycorrhizal Fungi on the Response of Potato to Phosphorus Deficiency.
Infections
Isolation and partial characterization of plasma membranes from the livers of control and Streptococcus pneumoniae-infected rats.
Infections
Juvenile hormone (JH) esterase activity but not JH epoxide hydrolase activity is downregulated in larval Adoxophyes honmai following nucleopolyhedroviruses infection.
Infections
Key residues of a major cytochrome P4502D6 epitope are located on the surface of the molecule.
Infections
Liver kidney microsomal type 1 antibodies reduce the CYP2D6 activity in patients with chronic hepatitis C virus infection.
Infections
Liver/kidney microsomal antibody type 1 targets CYP2D6 on hepatocyte plasma membrane.
Infections
Methimazole-mediated enhancement of albendazole oral bioavailability and anthelmintic effects against parenteral stages of Trichinella spiralis in mice: the influence of the dose-regime.
Infections
Mouse-adapted scrapie infection of SN56 cells: greater efficiency with microsome-associated versus purified PrP-res.
Infections
O-alkoxyamidine prodrugs of furamidine: in vitro transport and microsomal metabolism as indicators of in vivo efficacy in a mouse model of Trypanosoma brucei rhodesiense infection.
Infections
Participation of lipid peroxidation in the loss of hepatic drug-metabolizing activities in experimental fascioliasis in the rat.
Infections
Perinuclear localization of Na-K-Cl-cotransporter protein after human cytomegalovirus infection.
Infections
Polymorphisms of microsomal triglyceride transfer protein in different hepatitis B virus-infected patients.
Infections
Preserved cytosolic and synthetic liver function in jaundice of severe extrahepatic infection.
Infections
Prevalence and significance of thyroid autoantibodies in patients with chronic hepatitis C virus infection: a prospective controlled study.
Infections
Primary and secondary liver/kidney microsomal autoantibody response following infection with hepatitis C virus.
Infections
Status of hepatic glutathione-S-transferase(s) during Plasmodium berghei infection and chloroquine treatment in Mastomys natalensis.
Infections
Status of the microsomal mixed function oxidase system in the intestine, lungs and kidneys of hamsters during infection with Ancylostoma ceylanicum.
Infections
Studies of the hepatic mitochondrial and microsomal mixed-function oxidase system during Plasmodium yoelii infection and inducer treatment in Swiss albino mice.
Infections
Study of the B cell response to cytochrome P450IID6 in sera from chronic hepatitis C patients.
Infections
Suppression of the hepatic microsomal cytochrome P-450 dependent mixed function oxidase activities in golden hamster during Leishmania donovani infection.
Infections
Susceptibility to Helicobacter pylori infection: results of an epidemiological investigation among gastric cancer patients.
Infections
Synthesis and structure-activity relationships for extended side chain analogues of the antitubercular drug (6S)-2-nitro-6-{[4-(trifluoromethoxy)benzyl]oxy}-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine (PA-824).
Infections
Targeted Prostaglandin E2 Inhibition Enhances Antiviral Immunity through Induction of Type I Interferon and Apoptosis in Macrophages.
Infections
The hepatic and duodenal activities of some drug metabolizing enzymes in chickens: influence of infection with Escherichia coli endotoxin and coccidiosis.
Infections
The influence of Propionibacterium acnes (Corynebacterium parvum) fractions on immune response in vivo.
Infections
The restoring effect of trifluralin and benznidazole on the abnormal fatty-acid pattern induced by Trypanosoma cruzi in the liver microsomes of infected mice.
Infections
TISSUE METABOLISM IN INFECTION. LIVER MICROSOMAL ENZYMES OF MICE AND GUINEA PIGS IN EXPERIMENTAL TUBERCULOSIS.
Infections
Vaccination of mice against Leishmania mexicana amazonensis with microsomal fraction associated with BCG.
Infections
[Activity of microsomal N-acetyl-glucosaminyl-transferases in animal carriers of a Myxovirus infection]
Infections
[Autoantibodies in chronic hepatitis C. Markers of autoimmunity or non-specific events?]
Infections
[Biosynthesis of glycoproteins in animals with a myxovirus infection. I. Study of liver and spleen microsomal glucosaminyl-transferases]
Infections
[Heterogeneity of antimicrosomal autoantibodies in chronic hepatitis C virus infection and delta hepatitis]
Infections
[Microsomal hydroxylating system of the mouse liver in toxic forms of influenza infection]
Infertility
Generation of a mouse model with a reversible hypomorphic cytochrome P450 reductase gene: utility for tissue-specific rescue of the reductase expression, and insights from a resultant mouse model with global suppression of P450 reductase expression in extrahepatic tissues.
Infertility, Male
Integrated Analysis of DNA Methylation and mRNA Expression Profiles to Identify Key Genes in Severe Oligozoospermia.
Inflammatory Bowel Diseases
Common polymorphisms in the microsomal epoxide hydrolase and N-acetyltransferase 2 genes in association with inflammatory bowel disease in the Danish population.
Influenza, Human
A nucleoprotein peptide of influenza A virus stimulates assembly of HLA-B27 class I heavy chains and beta 2-microglobulin translated in vitro.
Influenza, Human
Lack of effect of influenza vaccine on the pharmacokinetics of antipyrine, alprazolam, paracetamol (acetaminophen) and lorazepam.
Influenza, Human
Posttranslational translocation of influenza virus hemagglutinin across microsomal membranes.
Influenza, Human
The influenza hemagglutinin insertion signal is not cleaved and does not halt translocation when presented to the endoplasmic reticulum membrane as part of a translocating polypeptide.
Influenza, Human
Translocation of peptides through microsomal membranes is a rapid process and promotes assembly of HLA-B27 heavy chain and beta 2-microglobulin translated in vitro.
Influenza, Human
Uncoupling of translocation across microsomal membranes from biosynthesis of influenza virus hemagglutinin.
Influenza, Human
[Microsomal hydroxylating system of the mouse liver in toxic forms of influenza infection]
Influenza, Human
[NEUTRALIZATION OF INFLUENZA BY MICROSOMAL FRACTIONS OF GUINEA PIG LIVER.]
Insulin Resistance
(13C)-Methacetin breath test provides evidence of subclinical liver dysfunction linked to fat storage but not lifestyle.
Insulin Resistance
Ablation of Elovl6 protects pancreatic islets from high-fat diet-induced impairment of insulin secretion.
Insulin Resistance
Ameliorated hepatic insulin resistance is associated with normalization of microsomal triglyceride transfer protein expression and reduction in very low density lipoprotein assembly and secretion in the fructose-fed hamster.
Insulin Resistance
Effect of long-term anticonvulsant therapy on glucose metabolism in humans.
Insulin Resistance
Enzyme inducers improve insulin sensitivity in non-insulin-dependent diabetic subjects.
Insulin Resistance
EPHX1 mutations cause a lipoatrophic diabetes syndrome due to impaired epoxide hydrolysis and increased cellular senescence.
Insulin Resistance
Insulin-mediated glucose metabolism is related to liver structure and microsomal function.
Insulin Resistance
Lipoprotein metabolism mediates the association of MTP polymorphism with beta-cell dysfunction in healthy subjects and in nondiabetic normolipidemic patients with nonalcoholic steatohepatitis.
Insulin Resistance
Mechanisms of hepatic very low density lipoprotein overproduction in insulin resistance. Evidence for enhanced lipoprotein assembly, reduced intracellular ApoB degradation, and increased microsomal triglyceride transfer protein in a fructose-fed hamster model.
Insulin Resistance
Microsomal triglyceride transfer protein inhibition improves insulin sensitivity and reduces atherogenic risk in Zucker fatty rats.
Insulin Resistance
Microsomal triglyceride transfer protein: does insulin resistance play a role in the regulation of chylomicron assembly?
Insulin Resistance
Oleate-mediated stimulation of microsomal triglyceride transfer protein (MTP) gene promoter: implications for hepatic MTP overexpression in insulin resistance.
Insulin Resistance
Possible role of microsomal epoxide hydrolase gene polymorphism as a risk factor for developing insulin resistance and type 2 diabetes mellitus.
Insulin Resistance
Up-regulation of liver glucose-6-phosphatase in rats fed with a P(i)-deficient diet.
Insulinoma
Rapid mobilization of Ca2+ from rat insulinoma microsomes by inositol-1,4,5-trisphosphate.
Insulinoma
Spontaneous secretion of thyroid autoantibodies by cultured peripheral blood lymphocytes from patients with Hashimoto's thyroiditis detected by micro-ELISA techniques.
Intellectual Disability
NADH cytochrome b5 reductase activity in lymphoid cell lines. Expression of the defect in epstein Barr virus transformed lymphoblastoid cell lines from patients with recessive congenital methemoglobinemia.
Intellectual Disability
Phenotypic variability among adult siblings with Sjögren-Larsson syndrome.
Intestinal Obstruction
The effect of intestinal obstruction on liver microsomal enzymes in rats.
Intestinal Obstruction
[State of the microsomal oxidative system of the rat liver in acute intestinal obstruction]
Intraabdominal Infections
Increased hepatic microsomal adenosine triphosphatase activity secondary to intra-abdominal infection.
Intracranial Aneurysm
Paradoxical Increase in Mortality and Rupture of Intracranial Aneurysms in Microsomal Prostaglandin E2 Synthase Type 1-Deficient Mice: Attenuation by Aspirin.
Intussusception
Myoepithelial hamartoma causing small-bowel intussusception: a case report and literature review.
Iron Deficiencies
Effect of long term iron deficiency on the activities of hepatic and extra-hepatic drug metabolising enzymes in Fischer rats.
Iron Deficiencies
Quantitative proteomics of Arabidopsis shoot microsomal proteins reveals a cross-talk between excess zinc and iron deficiency.
Iron Overload
Chronic dietary iron overload in rats results in impaired calcium sequestration by hepatic mitochondria and microsomes [corrected]
Iron Overload
Formation of liver microsomal MDA-protein adducts in mice with chronic dietary iron overload.
Iron Overload
Lipid peroxidation and associated hepatic organelle dysfunction in iron overload.
Iron Overload
Polyenylphosphatidylcholine opposes the increase of cytochrome P-4502E1 by ethanol and corrects its iron-induced decrease.
Ischemic Stroke
Missense Genetic Polymorphisms of Microsomal (EPHX1) and Soluble Epoxide Hydrolase (EPHX2) and Their Relation to the Risk of Large Artery Atherosclerotic Ischemic Stroke in a Turkish Population.
Keloid
[Treatment of keloids and hypertrophic scars. Pilot study with intralesional Lipotalon injections]
Keratosis
Aminopeptidase M and dipeptidyl peptidase IV activity in epithelial skin tumors: a histochemical study.
Keratosis, Seborrheic
Aminopeptidase M and dipeptidyl peptidase IV activity in epithelial skin tumors: a histochemical study.
Ketosis
Permanent diabetes without serological evidence of autoimmunity after transient neonatal diabetes.
Kidney Diseases
Drug metabolism under pathological and abnormal physiological states in animals and man.
Kidney Diseases
Effects of n-3 and n-6 fatty acids on the activities and expression of hepatic antioxidant enzymes in autoimmune-prone NZBxNZW F1 mice.
Kidney Failure, Chronic
Barbiturate and anticonvulsant treatment in relation to osteomalacia with haemodialysis and renal transplantation.
Kidney Failure, Chronic
Changes of hepatic microsomal oxidative drug metabolizing enzymes in chronic renal failure (CRF) rats by partial nephrectomy.
Kidney Failure, Chronic
Downregulation of Hepatic Carbonyl Reductase Type 1 in End-Stage Renal Disease.
Kidney Failure, Chronic
Hepatic metabolism of aminopyrine in patients with chronic renal failure.
Kidney Failure, Chronic
The plasma half-life of antipyrine in chromic uraemic and normal subjects.
Laryngeal Neoplasms
Combined effect of genetic polymorphisms in phase I and II biotransformation enzymes on head and neck cancer risk.
Laryngeal Neoplasms
High-activity microsomal epoxide hydrolase genotypes and the risk of oral, pharynx, and larynx cancers.
Laryngeal Neoplasms
Microsomal epoxide hydrolase and glutathione S-transferase polymorphisms in relation to laryngeal carcinoma risk.
Lecithin Cholesterol Acyltransferase Deficiency
Enzymic esterification of cholesterol in rat intestinal mucosa catalyzed by acyl-CoA: cholesterol acyltransferase.
Leiomyoma
Increased expression of type I 17beta-hydroxysteroid dehydrogenase enhances in situ production of estradiol in uterine leiomyoma.
Leiomyoma
Inhibition of in situ expression of aromatase P450 in leiomyoma of the uterus by leuprorelin acetate.
Leiomyoma
Suicide inactivation of aromatase in human placenta and uterine leiomyoma by 5 alpha-dihydronorethindrone, a metabolite of norethindrone, and its effect on steroid-producing enzymes.
Leishmaniasis
Changes in hepatic xenobiotic-metabolising enzymes in mouse liver following infection with Leishmania donovani.
Leishmaniasis
Lipid peroxidation in hepatic microsomal membranes isolated from mice in health and in experimental leishmaniasis.
Leishmaniasis, Visceral
Aminothiazoles: Hit to lead development to identify antileishmanial agents.
Leishmaniasis, Visceral
Suppression of the hepatic microsomal cytochrome P-450 dependent mixed function oxidase activities in golden hamster during Leishmania donovani infection.
Leptospirosis
Alterations in specific activity of glucose-6-phosphatase in laboratory rats after leptospiral exposure followed by triiodothyronine administration.
Leukemia
125I-labeled cell surface as a marker in preparation of microsome fraction by gel filtration.
Leukemia
Analysis of the characteristics and expression profiles of coding and noncoding RNAs of human dental pulp stem cells in hypoxic conditions.
Leukemia
Colocalization of leukotriene C synthase and microsomal glutathione S-transferase elucidated by indirect immunofluorescence analysis.
Leukemia
Emerging role of EPHX1 in chemoresistance of acute myeloid leukemia by regurlating drug-metabolizing enzymes and apoptotic signaling.
Leukemia
Increased gene expression in human promyeloid leukemia cells exposed to trans,trans-muconaldehyde, a hematotoxic benzene metabolite.
Leukemia
Leukotriene C synthetase, a special glutathione S-transferase: properties of the enzyme and inhibitor studies with special reference to the mode of action of U-60,257, a selective inhibitor of leukotriene synthesis.
Leukemia
Male mice deficient in microsomal epoxide hydrolase are not susceptible to benzene-induced toxicity.
Leukemia
Microsomal activation and increased production of 4'-(9-acridinylamino)-3-methanesulfon-m-anisidide (m-AMSA)-dependent, topoisomerase-associated DNA lesions in nuclei from human HL-60 leukemia cells.
Leukemia
Microsomal enzymes in patients with acute leukemia as determined by plasma half-life of antipyrine.
Leukemia
Myristoyl-CoA:protein N-myristoyltransferase activity in cancer cells. Purification and characterization of a cytosolic isoform from the murine leukemia cell line L1210.
Leukemia
Phenazone as a marker of liver-metabolic function in patients with acute leukemia.
Leukemia
Regulation of inositol 1,4,5-trisphosphate receptors in rat basophilic leukemia cells. I. Multiple conformational states of the receptor in a microsomal preparation.
Leukemia
Resolution and characterization of intracytoplasmic forms of reverse transcriptase from Rauscher leukemia virus-producing cells.
Leukemia
Solubilization and characterization of the leukotriene C4 synthetase of rat basophil leukemia cells: a novel, particulate glutathione S-transferase.
Leukemia
Subcellular distribution of newly synthesized virus-specific polypeptides in Moloney murine leukemia virus infected cells.
Leukemia
The effect of alpha-interferon on the liver in a patient with hairy cell leukemia: light and electron microscopic studies.
Leukemia L1210
125I-labeled cell surface as a marker in preparation of microsome fraction by gel filtration.
Leukemia, Hairy Cell
The effect of alpha-interferon on the liver in a patient with hairy cell leukemia: light and electron microscopic studies.
Leukemia, Lymphocytic, Chronic, B-Cell
Altered expression of nuclear non-histone protein (p44/46) in different stages of B-chronic lymphocytic leukemia.
Leukemia, Myeloid
Nuclear heme oxygenase-1 (HO-1) modulates subcellular distribution and activation of Nrf2, impacting metabolic and anti-oxidant defenses.
Leukemia, Myeloid
Quantitative profiling of differentiation-induced microsomal proteins using isotope-coded affinity tags and mass spectrometry.
Leukemia, Myeloid, Acute
Association of Glutathione S-Transferase, EPHX, and p53 codon 72 Gene Polymorphisms with Adult Acute Myeloid Leukemia.
Leukemia, Myeloid, Acute
Emerging role of EPHX1 in chemoresistance of acute myeloid leukemia by regurlating drug-metabolizing enzymes and apoptotic signaling.
Leukemia, Myeloid, Acute
Enzyme kinetics of GTI-2040, a phosphorothioate oligonucleotide targeting ribonucleotide reductase.
Leukemia, Myeloid, Acute
EPHX1 rs1051740 T>C (Tyr113His) is strongly associated with acute myeloid leukemia and KMT2A rearrangements in early age.
Leukemia, Myeloid, Acute
Phenazone as a marker of liver-metabolic function in patients with acute leukemia.
Leukemic Infiltration
Hepatic drug clearance in children with leukemia: changes in clearance of model substrates during remission-induction therapy.
Leukoencephalopathies
Phenotypic variability among adult siblings with Sjögren-Larsson syndrome.
Leukopenia
Protective role of thiols in cyclophosphamide-induced urotoxicity and depression of hepatic drug metabolism.
Lichen Planus
Lichen planus, liver kidney microsomal (LKM1) antibodies and hepatitis C virus antibodies.
Lichen Planus, Oral
Anemia and hematinic deficiencies in gastric parietal cell antibody-positive and antibody-negative erosive oral lichen planus patients with thyroid antibody positivity.
Lichen Planus, Oral
Gastric parietal cell and thyroid autoantibodies in recurrent aphthous stomatitis patients with concomitant oral lichen planus.
Lichen Planus, Oral
Modulation of serum anti-thyroglobulin and anti-thyroid microsomal autoantibody levels by levamisole in patients with oral lichen planus.
Lichen Planus, Oral
Significantly higher frequencies of presence of serum autoantibodies in Chinese patients with oral lichen planus.
Lipid Metabolism Disorders
Metformin improves lipid metabolism disorders through reducing the expression of microsomal triglyceride transfer protein in OLETF rats.
Lipid Metabolism Disorders
[Mechanism of action of the SIRT1-FoxO1-AdipoR2 signaling pathway in alcoholic fatty liver disease].
Lipodystrophy
Myo-inositol action on gerbil intestine: reversal of a diet-induced lipodystrophy and change in microsomal lipase activity.
Liver Cirrhosis
A proteomic analysis of thioacetamide-induced hepatotoxicity and cirrhosis in rat livers.
Liver Cirrhosis
Dietary nucleotides correct plasma and liver microsomal fatty acid alterations in rats with liver cirrhosis induced by oral intake of thioacetamide.
Liver Cirrhosis
Differential effects of hepatic cirrhosis on the intrinsic clearances of sorafenib and imatinib by CYPs in human liver.
Liver Cirrhosis
Downregulation of the male-specific hepatic microsomal steroid 16 alpha-hydroxylase, cytochrome P-450UT-A, in rats with portal bypass. Relevance to estradiol accumulation and impaired drug metabolism in hepatic cirrhosis.
Liver Cirrhosis
Effect of carbon tetrachloride--alcohol-induced liver fibrosis on microsomal mixed-function oxidases and the cytosolic glutathione-conjugating system in rat liver.
Liver Cirrhosis
Impaired androgen 16 alpha-hydroxylation in hepatic microsomes from carbon tetrachloride-cirrhotic male rats.
Liver Cirrhosis
Inducibility of microsomal liver function may differentiate cirrhotic patients with maintained compared with severely compromised liver reserve.
Liver Cirrhosis
Liver breath tests non-invasively predict higher stages of non-alcoholic steatohepatitis.
Liver Cirrhosis
Metabolism of antipyrine in vivo in two rat models of liver cirrhosis. Its relationship to intrinsic clearance in vitro and microsomal membrane lipid composition.
Liver Cirrhosis
The immunoelectron-microscopical demonstration of antibodies against endoplasmic reticulum (microsomes) in chronic aggressive hepatitis and liver cirrhosis.
Liver Cirrhosis
Treatment of liver cirrhosis with microsomal enzyme-inducing compound in the rat.
Liver Cirrhosis
[Non-organ specific anticytoplasmic autoantibodies. Immunoserologic detection and diagnostic relevance]
Liver Cirrhosis
[Psychometric hepatic encephalopathy score normalization data for the Portuguese population].
Liver Cirrhosis
[Time course of thioacetamide-induced changes in estrogen metabolism in the rat liver]
Liver Cirrhosis, Alcoholic
Decreased hepatic microsomal reserve in patients with cirrhosis. Studies using aminopyrine as model drug.
Liver Cirrhosis, Alcoholic
Hepatic ethanol elimination kinetics in patients with cirrhosis.
Liver Cirrhosis, Alcoholic
Hepatic [14C]aminopyrine demethylation capacity after portocaval shunting. Comparative study in patients with and without arterialization of portal vein.
Liver Cirrhosis, Alcoholic
Mitochondrial functions and content of microsomal and mitochondrial cytochromes in human cirrhosis.
Liver Cirrhosis, Alcoholic
Polymorphism in cytochrome P450 2E1 and interaction with other genetic risk factors and susceptibility to alcoholic liver cirrhosis.
Liver Cirrhosis, Alcoholic
The effect of alcoholic cirrhosis on the activities of microsomal aldrin epoxidase, 7-ethoxycoumarin O-de-ethylase and epoxide hydrolase, and on the concentrations of reduced glutathione in human liver.
Liver Cirrhosis, Alcoholic
The effect of alcoholic cirrhosis on the two kinetic components (high and low affinity) of the microsomal 0-deethylation of 7-ethoxycoumarin in human liver.
Liver Cirrhosis, Biliary
Detection of autoantibodies against M2, LKM-1, and SLA in liver diseases by standardized uniform ELISA-techniques.
Liver Cirrhosis, Biliary
IgG subclass distribution of autoantibodies to glomerular basement membrane in Goodpasture's syndrome compared to other autoantibodies.
Liver Cirrhosis, Biliary
Immunoblotting as a confirmatory test for antimitochondrial antibodies in primary biliary cirrhosis.
Liver Cirrhosis, Biliary
Prevalence and significance of abdominal lymphadenopathy in patients with chronic liver disease: an ultrasound study.
Liver Cirrhosis, Biliary
Regulation of renal cytochrome P-450. Effects of two-thirds hepatectomy, cholestasis, biliary cirrhosis and post-necrotic cirrhosis on hepatic and renal microsomal enzymes.
Liver Cirrhosis, Biliary
Serum antibodies to thymus epithelial cells in non-A, non-B and cryptogenic chronic liver disease.
Liver Cirrhosis, Biliary
The metabolism of 7-ethoxycoumarin in human liver microsomes and the effect of primary biliary cirrhosis: implications for studies of drug metabolism in liver disease.
Liver Cirrhosis, Biliary
Treatment of chronic type B hepatitis with recombinant alpha-interferon induces autoantibodies not specific for autoimmune chronic hepatitis.
Liver Diseases
A comprehensive autoantigen-ome of autoimmune liver diseases identified from dermatan sulfate affinity enrichment of liver tissue proteins.
Liver Diseases
Age-Dependent Human Hepatic Carboxylesterase 1 (CES1) and Carboxylesterase 2 (CES2) Postnatal Ontogeny.
Liver Diseases
Alcohol Metabolizing Enzymes, Microsomal Ethanol Oxidizing System, Cytochrome P450 2E1, Catalase, and Aldehyde Dehydrogenase in Alcohol-Associated Liver Disease.
Liver Diseases
Antipyrine clearance and metabolite excretion in Saudi patients with non-alcoholic chronic liver disease.
Liver Diseases
Antipyrine elimination and hepatic microsomal enzyme activity in patients with liver disease.
Liver Diseases
Association of Polymorphisms in Glutamate-Cysteine Ligase Catalytic Subunit and Microsomal Triglyceride Transfer Protein Genes with Nonalcoholic Fatty Liver Disease.
Liver Diseases
Association of polymorphisms of glutamate-cystein ligase and microsomal triglyceride transfer protein genes in non-alcoholic fatty liver disease.
Liver Diseases
Correlation between MTP -493G>T polymorphism and non-alcoholic fatty liver disease risk: a meta-analysis.
Liver Diseases
Critical appraisal of (13) C breath tests for microsomal liver function: aminopyrine revisited.
Liver Diseases
Cytochrome P4502D6(193-212): a new immunodominant epitope and target of virus/self cross-reactivity in liver kidney microsomal autoantibody type 1-positive liver disease.
Liver Diseases
Detection of liver-kidney microsomal autoantibodies by radioimmunoassay and their relation to anti-mitochondrial antibodies in inflammatory liver diseases.
Liver Diseases
Differential effects of hepatic cirrhosis on the intrinsic clearances of sorafenib and imatinib by CYPs in human liver.
Liver Diseases
Drug metabolism in liver disease: activity of hepatic microsomal metabolizing enzymes.
Liver Diseases
Enhancement of hepatic drug metabolism by glutethimide in patients with liver disease.
Liver Diseases
Heterogeneity of liver/kidney microsomal antibody type 1 in autoimmune hepatitis and hepatitis C virus related liver disease.
Liver Diseases
Impaired irinotecan biotransformation in hepatic microsomal fractions from patients with chronic liver disease.
Liver Diseases
Influence of liver disease and environmental factors on hepatic monooxygenase activity in vitro.
Liver Diseases
Inhibition of drug metabolism by cimetidine in man: dependence on pretreatment microsomal liver function.
Liver Diseases
Interferon therapy in liver/kidney microsomal antibody type 1-positive patients with chronic hepatitis C.
Liver Diseases
Intragraft iNOS induction during human liver allograft rejection depresses cytochrome p450 activity.
Liver Diseases
Leopard-like retinopathy and severe early-onset portal hypertension expand the phenotype of KARS1-related syndrome: a case report.
Liver Diseases
Lichen planus, liver kidney microsomal (LKM1) antibodies and hepatitis C virus antibodies.
Liver Diseases
Lipoprotein metabolism mediates the association of MTP polymorphism with beta-cell dysfunction in healthy subjects and in nondiabetic normolipidemic patients with nonalcoholic steatohepatitis.
Liver Diseases
Membrane bound diacylglycerols explain the dissociation of hepatic insulin resistance from steatosis in MTTP-/- mice.
Liver Diseases
Microsomal Epoxide Hydrolase Polymorphisms and Haplotypes as Determinants of Hepatitis B Virusand Hepatitis C Virus-related Liver Disease in Indian Population.
Liver Diseases
Microsomal triglyceride transfer protein and nonalcoholic fatty liver disease.
Liver Diseases
MTP -493G/T Polymorphism and Susceptibility to Nonalcoholic Fatty Liver Disease: A Meta-Analysis.
Liver Diseases
n-3 Polyunsaturated fatty acids for the management of alcoholic liver disease: A critical review.
Liver Diseases
New advances in the diagnosis of canine and feline liver and pancreatic disease.
Liver Diseases
Pediatric autoimmune liver diseases: the molecular basis of humoral and cellular immunity.
Liver Diseases
Phospholipid transmethylation and choline phosphotransferase in microsomal fraction of human diseased liver.
Liver Diseases
Polymorphism in microsomal triglyceride transfer protein: a link between liver disease and atherogenic postprandial lipid profile in NASH?
Liver Diseases
Polymorphisms of microsomal epoxide hydrolase gene and severity of HCV-related liver disease.
Liver Diseases
Polymorphisms of microsomal triglyceride transfer protein gene and phosphatidylethanolamine N-methyltransferase gene in alcoholic and nonalcoholic fatty liver disease in Koreans.
Liver Diseases
Prevention Mechanism of 2,3,5,4'-Tetrahydroxy-stilbene-2-O-?-D-glucoside on Lipid Accumulation in Steatosis Hepatic L-02 Cell.
Liver Diseases
Previous tuberculosis, hepatitis C virus and lichen planus. A report of 10 cases, a causal or casual link?
Liver Diseases
Proteomic Quantification of Changes in Abundance of Drug-Metabolizing Enzymes and Drug Transporters in Human Liver Cirrhosis: Different Methods, Similar Outcomes.
Liver Diseases
Quantitative analysis of hepatitis C virus activity in vivo in different groups of untreated patients.
Liver Diseases
Recurrent episodes of acute hepatitis associated with LKM-1 (cytochrome P450 2D6) antibodies in identical twin brothers.
Liver Diseases
Relationship between metabolic clearance rate of antipyrine and hepatic microsomal drug-oxidizing enzyme activities in humans without liver disease.
Liver Diseases
Salivary antipyrine kinetics in hepatic and renal disease and in patients on anticonvulsant therapy.
Liver Diseases
The aminopyrine breath test does not correlate with histologic disease severity in patients with cholestasis.
Liver Diseases
The association between SNPs rs1800591 and rs3816873 of the MTTP gene and nonalcoholic fatty liver disease: A meta-analysis.
Liver Diseases
The induction of autoimmune hepatitis in the human leucocyte antigen-DR4 non-obese diabetic mice autoimmune hepatitis mouse model.
Liver Diseases
The metabolism of 7-ethoxycoumarin in human liver microsomes and the effect of primary biliary cirrhosis: implications for studies of drug metabolism in liver disease.
Liver Diseases
Treatment of autoimmune and extrahepatic manifestations of hepatitis C virus infection.
Liver Diseases
Treatment of chronic type B hepatitis with recombinant alpha-interferon induces autoantibodies not specific for autoimmune chronic hepatitis.
Liver Diseases
Trial and error investigational drug induced liver injury, a case series report.
Liver Diseases
Use of liver breath tests to assess severity of nonalcoholic Fatty liver disease.
Liver Diseases
[Changes of serum 3,5,3'-triiodothyronine (T3), thyroxine (T4), 3,3',5'-triiodothyronine (rT3) levels in patients with liver diseases. One marker for hepatic microsomal function]
Liver Diseases
[Immunofluorescent-optical demonstration of microsomal antibodies in chronic liver diseases]
Liver Diseases
[Lipid peroxidation markers in the exhaled breath and microsomal oxidation in patients with chronic diffuse liver diseases]
Liver Diseases
[Lipoprotein (a) in liver diseases. Correlation between low levels and liver function]
Liver Diseases
[Liver diseases with microsomal antibodies. Frequency, clinical and immunological findings and course observations (author's transl)]
Liver Diseases
[Mechanism of action of the SIRT1-FoxO1-AdipoR2 signaling pathway in alcoholic fatty liver disease].
Liver Diseases
[Microsomal oxidative foreign-substance degradation by the human liver. Oxidative foreign-substance degradation by microsomal fractions of the liver withdrawn by needle biopsy, illustrated on the example of coumarin-7-hydroxylase and 7-ethoxycoumarin hydroxylase in persons with healthy livers and various liver diseases]
Liver Diseases
[Non-organ specific anticytoplasmic autoantibodies. Immunoserologic detection and diagnostic relevance]
Liver Diseases
[Plasma levels of cytoplasmic, mitochondrial and microsomal enzymes in animals administered carbon-tetrachloride and in patients with various liver diseases]
Liver Diseases, Alcoholic
Effects of dietary fat composition on activities of the microsomal ethanol oxidizing system and ethanol-inducible cytochrome P450 (CYP2E1) in the liver of rats chronically fed ethanol.
Liver Diseases, Alcoholic
Inhibition of hepatic drug metabolism by (+)-cyanidanol-3 (Catergen) in chronic alcoholic liver disease.
Liver Diseases, Alcoholic
n-3 Polyunsaturated fatty acids for the management of alcoholic liver disease: A critical review.
Liver Diseases, Alcoholic
Nutritional and metabolic effects of alcoholism: their relationship with alcoholic liver disease.
Liver Diseases, Alcoholic
Polymorphisms of the gene for microsomal epoxide hydrolase and susceptibility to alcoholic liver disease and hepatocellular carcinoma in a Caucasian population.
Liver Diseases, Alcoholic
Respective roles of human cytochrome P-4502E1, 1A2, and 3A4 in the hepatic microsomal ethanol oxidizing system.
Liver Diseases, Alcoholic
Role of cytochrome P-450 2E1 in ethanol-, carbon tetrachloride- and iron-dependent microsomal lipid peroxidation.
Liver Diseases, Alcoholic
Role of microsomal enzymes in development of alcoholic liver diseases.
Liver Diseases, Alcoholic
[A retrospective study on the role of antibodies against soluble liver antigen (anti-SLA antibodies) and other autoantibodies in the diagnostics of autoimmune hepatitis]
Liver Failure
Profile of urinary bile acids in familial intrahepatic cholestasis with Coombs' negative haemolytic anaemia.
Liver Failure
[Effect of sera from patients with liver failure on microsomal Na+, K+-ATPase activity of rat brain]
Liver Failure, Acute
[The correction of disorders in the microsomal oxidation system of the liver in experimental acute liver failure]
Liver Neoplasms
Altered lipid parameters in hepatic subcellular membrane fractions induced by fumonisin B1.
Liver Neoplasms
Association of reduction of AFB1-induced liver tumours by antioxidants with increased activity of microsomal enzymes.
Liver Neoplasms
Enzyme-activated nanoconjugates for tunable release of doxorubicin in hepatic cancer cells.
Liver Neoplasms
Immunohistochemical assessment of human microsomal epoxide hydrolase in primary and secondary liver neoplasm: a quantitative approach.
Liver Neoplasms
Inhibition of AFB1-induced liver cancer and induction of increased microsomal enzyme activity by dietary constituents.
Liver Neoplasms
Microsomal sphingomyelin accumulation in thioacetamide-injured regenerating rat liver: involvement of sphingomyelin synthase activity.
Liver Neoplasms
Polymorphisms of N-acetyltransferases, glutathione S-transferases, microsomal epoxide hydrolase and sulfotransferases: influence on cancer susceptibility.
Liver Neoplasms
Serum and liver glycylproline dipeptidyl aminopeptidase activity in rats with experimental hepatic cancer.
Liver Neoplasms
The impact of vitamins A,C,E, and selenium compound on prevention of liver cancer in rats.
Liver Neoplasms, Experimental
Analysis of the stearoyl-CoA desaturase system in the Morris hepatoma 7288C and 7288CTC.
Liver Neoplasms, Experimental
Carbohydrate composition of rat hepatocyte nuclear membrane as compared to normal, Morris hepatoma 7800, and phenobarbital-induced microsomal membranes.
Liver Neoplasms, Experimental
Comparative studies on the endogenous phosphorylation of microsomal membrane derived from Morris hepatoma, eight-day-old rats, and host livers in the presence of micromolar levels of Mg2+ ion.
Liver Neoplasms, Experimental
Comparison of serine palmitoyltransferase in Morris hepatoma 7777 and rat liver.
Liver Neoplasms, Experimental
Drug metabolism in the Novikoff hepatoma: evidence for a mixed function oxidase system and partial purification of cytochrome P-450 reductase.
Liver Neoplasms, Experimental
Effect of assay temperature on the kinetics of 3-hydroxy-3-methylglutaryl-coenzyme A reductase in rat liver and Morris hepatoma 5123C.
Liver Neoplasms, Experimental
Effect of nonspecific phospholipid transfer protein on cholesterol esterification in microsomes from Morris hepatomas.
Liver Neoplasms, Experimental
Effects of phenobarbital and 3-methylcolanthrene treatment on microsomes of Morris hepatoma 3924-A, tumour-bearing and normal rat liver.
Liver Neoplasms, Experimental
Electrophoretic analysis of microsomal smooth membrane proteins in rat liver and in Morris hepatoma 5123C.
Liver Neoplasms, Experimental
Ethanol metabolism by a transplantable hepatocellular carcinoma. Role of microsomes and mitochondria.
Liver Neoplasms, Experimental
Inhibition of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in Morris hepatoma 7800 after intravenous injection of mevalonic acid.
Liver Neoplasms, Experimental
Isolation and partial characterization of a cytochrome P-450 isoenzyme (cytochrome P-450tu) from mouse liver tumors.
Liver Neoplasms, Experimental
Lipid peroxidation and lipid antioxidants in normal and tumor cells.
Liver Neoplasms, Experimental
Microsomal cAMP-independent histone H1 kinase activity in plasmacytoma, Morris hepatoma and normal liver.
Liver Neoplasms, Experimental
Mitochondrial and microsomal phospholipids of Morris hepatoma 7777.
Liver Neoplasms, Experimental
Nonspecific lipid transfer proteins as probes of membrane structure and function.
Liver Neoplasms, Experimental
O2-dependent lipid peroxidation does not affect the molecular order in hepatoma microsomes.
Liver Neoplasms, Experimental
Restoration of hydroperoxide-dependent lipid peroxidation by 3-methylcholanthrene induction of cytochrome P-448 in hepatoma microsomes.
Lung Diseases
Microsomal epoxide hydrolase is not associated with COPD in a community-based sample.
Lung Diseases
Polymorphism in gene for microsomal epoxide hydrolase and lung disease.
Lung Injury
Association of changes in lysophosphatidylcholine metabolism and in microsomal membrane lipid composition to the pulmonary injury induced by oleic acid.
Lung Injury
Lung injury induced by pyrrolizidine alkaloids depends on metabolism by hepatic cytochrome P450s and blood transport of reactive metabolites.
Lung Injury
Metabolic sources of reactive oxygen metabolites during oxidant stress and ischemia with reperfusion.
Lung Injury
Potentiation of oxygen-induced lung injury in rats by the mechanism-based cytochrome P-450 inhibitor, 1-aminobenzotriazole.
Lung Injury
Studies on the interaction of bleomycin A2 with rat lung microsomes. I. Characterization of factors which influence bleomycin-mediated DNA chain breakage.
Lung Injury
[Protective effect of low concentration endothelin-1 on the reactive oxygen-induced inhibition of pulmonary surfactant lipid synthesis]
Lung Neoplasms
A comprehensive analysis of phase I and phase II metabolism gene polymorphisms and risk of non-small cell lung cancer in smokers.
Lung Neoplasms
Alterations in the pulmonary microsomal cytochrome P-450 system after exposure of rats to silica.
Lung Neoplasms
Aromatic DNA adducts and number of lung cancer risk alleles in Map-Ta-Phut Industrial Estate workers and nearby residents.
Lung Neoplasms
Association between EPHX1 rs1051740 and lung cancer susceptibility: a meta-analysis.
Lung Neoplasms
Association between microsomal epoxide hydrolase 1 T113C polymorphism and susceptibility to lung cancer.
Lung Neoplasms
Association of CYP1A1 and microsomal epoxide hydrolase polymorphisms with lung squamous cell carcinoma.
Lung Neoplasms
Association of functionally important polymorphism of microsomal epoxide hydrolase gene (EPHX1) with lung cancer susceptibility.
Lung Neoplasms
Association of microsomal epoxide hydrolase polymorphisms and lung cancer risk.
Lung Neoplasms
Combined analysis of polymorphisms in glutathione S-transferase M1 and microsomal epoxide hydrolase in lung cancer patients.
Lung Neoplasms
Determination of the role of target tissue metabolism in lung carcinogenesis using conditional cytochrome P450 reductase-null mice.
Lung Neoplasms
Effect of epoxide hydrolase polymorphisms on chromosome aberrations and risk for lung cancer.
Lung Neoplasms
EPHX1 rs2234922 polymorphism and lung cancer susceptibility in Asian populations: a meta-analysis.
Lung Neoplasms
Functional polymorphisms of the microsomal epoxide hydrolase gene: A reappraisal on a early-onset lung cancer patients series.
Lung Neoplasms
Genetic analysis of microsomal epoxide hydrolase gene and its association with lung cancer risk.
Lung Neoplasms
Genetic polymorphism and gene expression of microsomal epoxide hydrolase in non-small cell lung cancer.
Lung Neoplasms
Genetic Polymorphism of Epoxide Hydrolase and GSTM1 in Lung Cancer Susceptibility of Korean Population.
Lung Neoplasms
Genetic polymorphism of xenobiotic metabolizing enzymes among Chinese lung cancer patients.
Lung Neoplasms
Genetic polymorphisms in N-acetyltransferase-2 and microsomal epoxide hydrolase, cumulative cigarette smoking, and lung cancer.
Lung Neoplasms
Genetic polymorphisms of MPO, GSTT1, GSTM1, GSTP1, EPHX1 and NQO1 as risk factors of early-onset lung cancer.
Lung Neoplasms
Genetic polymorphisms of NAD(P)H quinone oxidoreductase, CYP1A1 and microsomal epoxide hydrolase and lung cancer risk in Nanjing, China.
Lung Neoplasms
Impact of epoxide hydrolase 1 polymorphisms on lung cancer susceptibility in asian populations.
Lung Neoplasms
Lung cancer risk in relation to genetic polymorphisms of microsomal epoxide hydrolase among African-Americans and Caucasians in Los Angeles County.
Lung Neoplasms
Lung cancer susceptibility in relation to combined polymorphisms of microsomal epoxide hydrolase and glutathione S-transferase P1.
Lung Neoplasms
Microsomal epoxide hydrolase genotypes and chronic obstructive pulmonary disease in Japanese.
Lung Neoplasms
Microsomal epoxide hydrolase polymorphisms and lung cancer risk in non-Hispanic whites.
Lung Neoplasms
Microsomal epoxide hydrolase polymorphisms and lung cancer risk: a quantitative review.
Lung Neoplasms
Multiple analytical approaches reveal distinct gene-environment interactions in smokers and non smokers in lung cancer.
Lung Neoplasms
NAD+-linked 15-hydroxyprostaglandin dehydrogenase (15-PGDH) behaves as a tumor suppressor in lung cancer.
Lung Neoplasms
Phase I metabolic genes and risk of lung cancer: multiple polymorphisms and mRNA expression.
Lung Neoplasms
Polymorphism of selected enzymes involved in detoxification and biotransformation in relation to lung cancer.
Lung Neoplasms
Polymorphisms in the microsomal epoxide hydrolase gene: role in lung cancer susceptibility and prognosis.
Lung Neoplasms
Pulmonary microsomal metabolism of benzo[a]pyrene following exposure of rats to silica.
Lung Neoplasms
Quantitative assessment of the effects of the EPHX1 Tyr113His polymorphism on lung and breast cancer.
Lung Neoplasms
Quantitative membrane proteomics applying narrow range peptide isoelectric focusing for studies of small cell lung cancer resistance mechanisms.
Lung Neoplasms
Signal peptide peptidase promotes tumor progression via facilitating FKBP8 degradation.
Lung Neoplasms
The association of microsomal epoxide hydrolase polymorphisms and lung cancer risk in African-Americans and Mexican-Americans.
Lung Neoplasms
The interaction between microsomal epoxide hydrolase polymorphisms and cumulative cigarette smoking in different histological subtypes of lung cancer.
Lung Neoplasms
[Assessment of the functional state of microsomal enzymes in the liver in patients with small cell lung cancer treated with cytostatic drugs]
Lung Neoplasms
[The interaction between microsomal epoxide hydrolase polymorphisms and indoor pollution in non small cell lung cancer]
Lupus Erythematosus, Systemic
Cytochrome P-450 mediated metabolism in active murine systemic lupus erythematosus.
Lupus Erythematosus, Systemic
Distinction between natural and pathological autoantibodies by immunoblotting and densitometric subtraction: liver-kidney microsomal antibody (LKM) positive sera identify multiple antigens in human liver tissue.
Lupus Erythematosus, Systemic
Estrogen metabolism in the (New Zealand black x New Zealand white)F1 murine model of systemic lupus erythematosus.
Lupus Erythematosus, Systemic
Microsomal hydroxylation as measured by pentobarbital elimination in patients with idiopathic systemic lupus erythematosus.
Lymphadenopathy
Prevalence and significance of abdominal lymphadenopathy in patients with chronic liver disease: an ultrasound study.
Lymphatic Metastasis
Next-generation sequencing reveals lymph node metastasis associated genetic markers in colorectal cancer.
Lymphoma
Alterations of drug-induced toxicity in the mouse lymphoma assay by a rat hepatic microsomal metabolizing system (S-9).
Lymphoma
Bromodeoxyuridine resistance induced in mouse lymphoma cells by microsomal activation of dimethylnitrosamine.
Lymphoma
Cell-free synthesis and membrane insertion of mouse H-2Dd histocompatibility antigen and beta 2-microglobulin.
Lymphoma
Chimeric bovine-human growth hormone prepared by recombinant DNA technology: binding properties and biological activity.
Lymphoma
Choline incorporation into phospholipids by microsomal fractions from L5178Y lymphoma.
Lymphoma
Comparative study of in vitro and in vivo modulation of lactogenic and somatotropic receptors by native human growth hormone and its modified analog prepared by recombinant deoxyribonucleic acid technology.
Lymphoma
Corticosteroids and phosphatidylcholine biosynthesis in microsomal fractions from L5178Y lymphoma.
Lymphoma
Direct evidence that lactogenic hormones induce homodimerization of membrane-anchored prolactin receptor in intact Nb2-11C rat lymphoma cells.
Lymphoma
Evidence that murine hematopoietic cell subset marker J11d is attached to a glycosyl-phosphatidylinositol membrane anchor.
Lymphoma
Genetic polymorphisms of biotransformation enzymes in patients with Hodgkin's and non-Hodgkin's lymphomas.
Lymphoma
Human ovarian cancer, lymphoma spleen, and bovine milk GlcNAc:beta1,4Gal/GalNAc transferases: two molecular species in ovarian tumor and induction of GalNAcbeta1,4Glc synthesis by alpha-lactalbumin.
Lymphoma
Protective role of vanadium in the survival of hosts during the growth of a transplantable murine lymphoma and its profound effects on the rates and patterns of biotransformation.
Lymphoma
Role of vitamin D3 on the activity patterns of hepatic drug metabolizing enzymes in transplantable murine lymphoma.
Lymphoma
Site-directed mutations of human growth hormone that selectively modify its lactogenic activity and binding properties.
Lymphoma
The metabolism of N-acetyl-2-aminofluorene to a mutagen in L5178Y/TK+/-mouse lymphoma cells.
Lymphoma
Two enzymes involved in the synthesis of O-linked oligosaccharides are localized on membranes of different densities in mouse lymphoma BW5147 cells.
Lymphoma, B-Cell
Genetic variation in metabolic genes, occupational solvent exposure, and risk of non-hodgkin lymphoma.
Lymphoma, Large B-Cell, Diffuse
Genetic variation in metabolic genes, occupational solvent exposure, and risk of non-hodgkin lymphoma.
Lymphoma, Non-Hodgkin
Alterations in hepatic heme and cytochrome P-450 metabolism in Murphy-Sturm lymphosarcoma-bearing rats. Implications for drug metabolism.
Lymphoma, Non-Hodgkin
Phenazone pharmacokinetics as an index of hepatic metabolic efficiency.
Lymphoproliferative Disorders
Human spleen heme oxygenase and microsomal electron transport system component activity in normals and in patients with hemolytic anemia, idiopathic thrombocytopenic purpura, and lymphoproliferative disorders.
Macular Degeneration
Genetic association of manganese superoxide dismutase with exudative age-related macular degeneration.
Macular Degeneration
Phenotypic variability among adult siblings with Sjögren-Larsson syndrome.
Macular Degeneration
Retina expresses microsomal triglyceride transfer protein: implications for age-related maculopathy.
Malaria
Discovery of carbohybrid-based 2-aminopyrimidine analogues as a new class of rapid-acting antimalarial agents using image-based cytological profiling assay.
Malaria
Effect of malaria infection and endotoxin-induced fever on phenacetin O-deethylation by rat liver microsomes.
Malaria
Non-detergent sulphobetaines: a new class of mild solubilization agents for protein purification.
Malaria
[Detection of a system of microsomal monooxygenases in the rodent malaria parasite Plasmodium berghei]
Malnutrition
Effect of chloramphenicol on hepatic mitochondrial and microsomal functions in protein-energy malnourishment.
Malnutrition
Effect of protein and calorie malnutrition on drug metabolism in rat - in vitro.
Malnutrition
Induction of microsomal drug metabolizing enzymes by oral contraceptives in protein-malnourished rats.
Malnutrition
Influence of vitamin E and selenium on glutathione-dependent protection against microsomal lipid peroxidation.
Malnutrition
Microsomal enzymes in malnutrition as determined by plasma half life of antipyrine.
Malnutrition
Rehabilitation of microsomal enzymes in malnourished rats: Comparison of parenteral versus oral refeeding.
Malnutrition
The fetal somatotropic axis during long term maternal undernutrition in sheep: evidence for nutritional regulation in utero.
Malnutrition
The role of dietary aflatoxin in the genesis of hepatocellular cancer in developing countries.
Malnutrition
Undernutrition in the neonate: long-term effects upon mitochondrial and microsomal constituents of the rat hepatocyte.
Marek Disease
Marek's disease vaccination, with turkey herpesvirus, and enrofloxacin modulate the activities of hepatic microsomal enzymes in broiler chickens.
Massive Hepatic Necrosis
Increase of UDP-glucuronosyltransferase activities toward xenobiotics during the development of hereditary hepatitis in LEC rats.
Massive Hepatic Necrosis
Occurrence of autoimmune antibodies to liver microsomal proteins in association with fulminant hepatitis in the LEC strain of rats.
Massive Hepatic Necrosis
Serum thyroid hormone, triiodothyronine, thyroxine, and triiodothyronine/thyroxine ratio in patients with fulminant, acute, and chronic hepatitis.
Mastocytoma
Biosynthesis of glycosoaminoglycans by microsomal preparations from cultured mastocytoma cells.
Mastocytoma
Biosynthesis of heparin. Concerted action of late polymer-modification reactions.
Mastocytoma
Biosynthesis of heparin. Modulation of polysaccharide chain length in a cell-free system.
Mastocytoma
Biosynthesis of heparin. Relationship between the polymerization and sulphation processes.
Mastocytoma
Biosynthesis of heparin. Solubilization and partial characterization of N- and O-sulphotransferases.
Mastocytoma
Biosynthesis of heparin. The D-glucuronosyl- and N-acetyl-D-glucosaminyltransferase reactions and their relation to polymer modification.
Mastocytoma
Biosynthesis of heparin/heparan sulfate. The D-glucosaminyl 3-O-sulfotransferase reaction: target and inhibitor saccharides.
Mastocytoma
Colocalization of leukotriene C synthase and microsomal glutathione S-transferase elucidated by indirect immunofluorescence analysis.
Mastocytoma
Leukotriene C synthase in mouse mastocytoma cells. An enzyme distinct from cytosolic and microsomal glutathione transferases.
Mastocytoma
Relationship of sulfation to ongoing chondroitin polymerization during biosynthesis of chondroitin 4-sulfate by microsomal preparations from cultured mouse mastocytoma cells.
Mastocytoma
Simultaneous sulfation of endogenous chondroitin sulfate and chondroitin-derived oligosaccharides. Studies with separate 4-sulfating and 6-sulfating microsomal systems.
Mastocytoma
Substrate specificities of glycosyltransferases involved in formation of heparin precursor and E. coli K5 capsular polysaccharides.
Mastocytoma
Sulfation of chondroitin. Specificity, degree of sulfation, and detergent effects with 4-sulfating and 6-sulfating microsomal systems.
Medulloblastoma
Maternal variation in EPHX1, a xenobiotic metabolism gene, is associated with childhood medulloblastoma: an exploratory case-parent triad study.
Melanoma
Human melanomas of fibroblast and epithelial morphology differ widely in their ability to synthesize retinyl esters.
Melanoma
Isolation of the major component in white snakeroot that is toxic after microsomal activation: possible explanation of sporadic toxicity of white snakeroot plants and extracts.
Melanoma
Melanocyte-stimulating hormone (alpha-MSH) inhibits the growth of human malignant melanoma cells with the induction of phosphatidyl inositol and myo-inositol phosphate levels.
Melanoma
Microsomal activation of constituents of white snakeroot (Eupatorium rugosum Houtt) to form toxic products.
Melanoma
Properties of the nerve growth factor receptor. Relationship between receptor structure and affinity.
Melanoma
Structural toxicity relationship of 4-alkoxyphenols' cytotoxicity towards murine B16-F0 melanoma cell line.
Melanoma
Tyrosinase isoenzymes in mammalian melanocytes. 1. Biochemical characterization of two melanosomal tyrosinases from B16 mouse melanoma.
Melanoma, Experimental
Melanocyte stimulating hormone activation of tyrosinase in B16 mouse melanoma cells. Evidence for a differential induction of two distinct isoenzymes.
Melanoma, Experimental
[Investigation of tyrosinase activity and phospholipid composition in Harding-Passey melanoma microsomal fraction]
Meningioma
Biochemical characterization of 17 beta-hydroxysteroid dehydrogenase in human meningioma.
Menopause, Premature
Partially compensated hypoadrenalism presenting with persistent skin pigmentation.
Mesothelioma, Malignant
Metabolic genotypes as modulators of asbestos-related pleural malignant mesothelioma risk: a comparison of Finnish and Italian populations.
Metabolic Diseases
Microsomal Triglyceride Transfer Protein: From Lipid Metabolism to Metabolic Diseases.
Metabolic Syndrome
Analysis of alternative promoter usage in expression of HSD11B1 including the development of a transcript-specific quantitative real-time PCR method.
Metabolic Syndrome
Energy-restricted Central-European diet stimulates liver microsomal function in obese postmenopausal women - a randomized nutritional trial with a comparison to energy-restricted Mediterranean diet.
Metabolic Syndrome
Genetic variants of microsomal triglyceride transfer protein (MTTP) are associated with metabolic syndrome in schizophrenic patients treated with atypical antipsychotics.
Metabolic Syndrome
Glycogen storage disease type Ia (GSDIa) but not Glycogen storage disease type Ib (GSDIb) is associated to an increased risk of metabolic syndrome: possible role of microsomal glucose 6-phosphate accumulation.
Metabolic Syndrome
Impaired microsomal oxidation of the atypical antipsychotic agent clozapine in hepatic steatosis.
Metabolic Syndrome
The influence of polymorphism of -493G/T MTP gene promoter and metabolic syndrome on lipids, fatty acids and oxidative stress.
Methemoglobinemia
An investigation into the formation of tebufenozide's toxic aromatic amine metabolites in human in vitro hepatic microsomes.
Methemoglobinemia
Cytochrome b5 reductase: the roles of the recessive congenital methemoglobinemia mutants P144L, L148P, and R159*.
Methemoglobinemia
Heterologous expression of enzymopenic methemoglobinemia variants using a novel NADH:cytochrome c reductase fusion protein.
Methemoglobinemia
Metabolism of the arylamide herbicide propanil. I. Microsomal metabolism and in vitro methemoglobinemia.
Methemoglobinemia
Suppression of phenacetin-induced methemoglobinemia by diethyldithiocarbamate and carbon disulfide and its relation to phenacetin metabolism in mice.
Methemoglobinemia
[Induction of hepatic microsomal drug metabolizing enzymes and methemoglobinemia induced by local anesthetics]
microsomal epoxide hydrolase deficiency
Microsomal epoxide hydrolase deletion enhances tyrosine hydroxylase phosphorylation in mice after MPTP treatment.
Miosis
Preclinical toxicology studies with nizatidine, a new H2-receptor antagonist: acute, subchronic, and chronic toxicity evaluations.
Mouth Neoplasms
Lack of Association of EPHX1 Genotypes and Haplotypes with Oral Cancer in South Indians.
Mouth Neoplasms
Multifocal epithelial hyperplasia: A potentially precancerous disease? (Review).
Mucopolysaccharidoses
Specific inhibition of human beta-D-glucuronidase and alpha-L-iduronidase by a trihydroxy pipecolic acid of plant origin.
Multiple Sclerosis
Metabolic Profiling of a CB2 Agonist, AM9338, Using LC-MS and Microcoil-NMR: Identification of a Novel Dihydroxy Adamantyl Metabolite.
Muscular Dystrophies
Preclinical increase in activity of muscle microsomal trypsin-like protease in murine muscular dystrophy, C57BL/10-mdx.
Muscular Dystrophies
Sarocoplasmic reticulum. VI. Microsomal Ca2+ transport in genetic muscular dystrophy of mice.
Muscular Dystrophy, Duchenne
Muscle ribosome detachment factor. Does it have a role in the pathogenesis of Duchenne muscular dystrophy?
Muscular Dystrophy, Duchenne
Therapeutic effect of camostat mesilate on Duchenne muscular dystrophy in mdx mice.
Myasthenia Gravis
Clinical and immunological associations in myasthenia gravis. 1: Autoantibodies.
Myasthenic Syndromes, Congenital
Unusual association of insulin-dependent diabetes mellitus with congenital myasthenia gravis and autoimmune thyroid disease.
Myelodysplastic Syndromes
Downregulation of carnitine acyltransferases and organic cation transporter OCTN2 in mononuclear cells in healthy elderly and patients with myelodysplastic syndromes.
Myocardial Infarction
Microsomal epoxide hydrolase genotype and risk of myocardial infarction.
Myocardial Infarction
[Changes in fatty acid composition and lipid peroxidation activity in microsomal membranes of the liver in experimental myocardial infarct]
Myocardial Infarction
[Experimental myocardial infarction in atherosclerosis--various methods of pharmacological correction]
Myocardial Infarction
[Functioning of the monooxygenase system of the liver in experimental myocardial infarct]
Myocardial Ischemia
Allele-specific regulation of MTTP expression influences the risk of ischemic heart disease.
Myocardial Ischemia
Hydrogen sulfide modulates sub-cellular susceptibility to oxidative stress induced by myocardial ischemic reperfusion injury.
Myocardial Ischemia
Lack of effect of methylprednisolone on lysosomal and microsomal enzymes after two hours of well-defined canine myocardial ischemia.
Myocardial Ischemia
Regulation of lysophosphatidylcholine-metabolizing enzymes in isolated myocardial cells from rat heart.
Myocardial Ischemia
[Activity of microsomal oxidation and biochemical characteristics of the sympathico-adrenal system in myocardial ischemia in rats]
Myocardial Ischemia
[Oxidative stress and hepatic monooxygenase function in patients with coronary heart disease before and after cardiac surgery]
Myocardial Ischemia
[Treatment of arrhythmia in patients with chronic ischemic heart disease using kinilentin combined with an inhibitor or inductor of microsomal oxidation]
Myxedema
L-thyroxine therapy induces a fall of thyroid microsomal and thyroglobulin antibodies in idiopathic myxedema and in hypothyroid, but not in euthyroid Hashimoto's thyroiditis.
Myxedema
Thyroid autoantigens and their relevance in the pathogenesis of thyroid autoimmunity.
nadph-hemoprotein reductase deficiency
P450 oxidoreductase deficiency: a new disorder of steroidogenesis affecting all microsomal P450 enzymes.
Neoplasm Metastasis
Epithelioid hemangioendothelioma of the mandibular gingiva: A rare case of metastasis 4 years after radical excision and literature review.
Neoplasm Metastasis
Immunohistochemical assessment of human microsomal epoxide hydrolase in primary and secondary liver neoplasm: a quantitative approach.
Neoplasm Metastasis
Inhibitory effect of a biscoclaurine alkaloid, cepharanthin, on lung metastasis of Lewis lung carcinoma.
Neoplasm Metastasis
Next-generation sequencing reveals lymph node metastasis associated genetic markers in colorectal cancer.
Neoplasms
15-deoxy-Delta12,14-prostaglandin J2 inhibits the expression of microsomal prostaglandin E synthase type 2 in colon cancer cells.
Neoplasms
3 beta-hydroxysteroid dehydrogenase/delta 5----4-isomerase expression in rat and characterization of the testis isoform.
Neoplasms
A Multi-step Virtual Screening Protocol for the Identification of Novel Non-acidic Microsomal Prostaglandin?E2 Synthase-1 (mPGES-1) Inhibitors.
Neoplasms
A phylogenetic analysis identifies heterogeneity among hepatocellular carcinomas.
Neoplasms
A unique highly oxygenated pyrano[4,3-c][2]benzopyran-1,6-dione derivative with antioxidant and cytotoxic activities from the fungus Phellinus igniarius.
Neoplasms
Abnormal membrane phospholipid content in subcellular fractions from the Morris 7777 hepatoma.
Neoplasms
Accelerated elimination of pimonidazole following microsomal enzyme induction in mice: a possible approach to reduced neurotoxicity of the pimonidazole-etanidazole combination.
Neoplasms
Activation of the anti-cancer drug ifosphamide by rat liver microsomal P450 enzymes.
Neoplasms
Adrenal microsomal C19-steroid 5alpha-reductase activity in the Snell transplantable rat adrenocortical tumour 494 and the effect of oestradiol, testosterone propionate and adrenocorticotrophin in intact and gonadectomized rats.
Neoplasms
Aetiology of jaagsiekte: transmission by means of subcellular fractions and evidence for the involvement of a retrovirus.
Neoplasms
Alterations in hepatic heme and cytochrome P-450 metabolism in Murphy-Sturm lymphosarcoma-bearing rats. Implications for drug metabolism.
Neoplasms
Alterations of hepatic delta-aminolevulinic acid synthetase, heme oxygenase, microsomal cytochrome content and drug metabolism in rats bearing ascitic tumors AH 13, AH 66 and AH 414 and a 3-methylcholanthrene induced tumor.
Neoplasms
Altered distribution of constitutive forms of microsomal cytochrome P-450 in tumor-bearing mouse liver.
Neoplasms
Analogues of hexamethylmelamine. The anti-neoplastic activity of derivatives with enhanced water solubility.
Neoplasms
Antiestrogen binding sites in microsomal fractions of malignant and nonmalignant human breast tissues.
Neoplasms
Antihyperlipidaemic effect of triterpenic acid-enriched fraction from Cyclocarya paliurus leaves in hyperlipidaemic rats.
Neoplasms
Antitumor agents. II. Effect of 5-fluorouracil and cyclophosphamide on immunological parameters and liver microsomes of tumor-bearing rats.
Neoplasms
Apogossypol derivatives as pan-active inhibitors of antiapoptotic B-cell lymphoma/leukemia-2 (Bcl-2) family proteins.
Neoplasms
Application of a microsomal drug activation system in a human tumor cloning assay.
Neoplasms
Assessment of Genetic Aspects of Non-alcoholic Fatty Liver and Premature Cardiovascular Events.
Neoplasms
Association between head and neck cancer and microsomal epoxide hydrolase genotypes.
Neoplasms
Association of Activity Altering Genotypes - Tyr113His and His139Arg in Microsomal Epoxide Hydrolase Enzyme with Esophageal Squamous Cell Carcinoma.
Neoplasms
Association of microsomal epoxide hydrolase exon 3 Tyr113His and exon 4 His139Arg polymorphisms with gastric cancer in India.
Neoplasms
Association of reduction of AFB1-induced liver tumours by antioxidants with increased activity of microsomal enzymes.
Neoplasms
Associations between smoking, polymorphisms in polycyclic aromatic hydrocarbon (PAH) metabolism and conjugation genes and PAH-DNA adducts in prostate tumors differ by race.
Neoplasms
Bioactive Properties of Tynanthus panurensis (Bureau) Sanwith Bark Extract, the Amazonian "Clavo Huasca".
Neoplasms
Biological markers as an aid in the clinical management of patients with liver metastases.
Neoplasms
Biosynthesis of an O-alkyl analogue of phosphatidic acid and O-alkylglycerols via O-alkyl ketone intermediates by microsomal enzymes of Ehrlich ascites tumor.
Neoplasms
Biosynthesis of heparin. 3. Formation of a sulfated glycosaminoglycan with a microsomal preparation from mast cell tumors.
Neoplasms
cADP-ribose/ryanodine channel/Ca2+-release signal transduction pathway in mesangial cells.
Neoplasms
Carbohydrate processing of thyrotropin differs from that of free alpha-subunit and total glycoproteins in microsomal subfractions of mouse pituitary tumor.
Neoplasms
Carbon tetrachloride promoted malondialdehyde formation in liver microsomal and nuclear preparations from Sprague Dawley or Osborne Mendel male rats.
Neoplasms
Changes in GTP-dependent fusion and ras-related proteins in membranes from rat hepatocellular carcinomas.
Neoplasms
Characterization of 3-hydroxy-3-methylglutaryl coenzyme A reductase in human adrenal cortex.
Neoplasms
Characterization of an extracellular matrix-degrading protease derived from a highly metastatic tumor cell line.
Neoplasms
Characterization of peripheral benzodiazepine receptors in rat prostatic adenocarcinoma.
Neoplasms
Characterization of two phase I metabolites of bendamustine in human liver microsomes and in cancer patients treated with bendamustine hydrochloride.
Neoplasms
Chemopreventive effect of Ginkgo biloba extract against benzo(a)pyrene-induced forestomach carcinogenesis in mice: amelioration of doxorubicin cardiotoxicity.
Neoplasms
Cigarette smoke induces cyclooxygenase-2 and microsomal prostaglandin E2 synthase in human lung fibroblasts: implications for lung inflammation and cancer.
Neoplasms
Combined cancer chemotherapy with cyclophoshamide and an inducer of microsomal drug-metabolizing enzymes (cytochrome P-450) in tumor-bearing rats.
Neoplasms
Common precursor molecule as origin for the ectopic-hormone-producing-tumour syndrome.
Neoplasms
Comparative in vitro cytotoxicity of cyclophosphamide, its major active metabolites and the new oxazaphosphorine ASTA Z 7557 (INN mafosfamide).
Neoplasms
Comparative studies on estrogen receptors between a pregnancy-dependent mouse mammary tumor (TPDMT-4) and related autonomous tumors.
Neoplasms
Comparison of enzyme phenotypes in human bladder tumours and experimentally induced hyperplastic and neoplastic lesions of the rat urinary bladder. A combined histochemical and immunohistochemical approach.
Neoplasms
Covalent binding of carbon tetrachloride reactive metabolites to liver microsomal and nuclear lipid and phospholipid classes from Sprague Dawley and osborne Mendel male rats.
Neoplasms
COX-2 Limits Prostanoid Production in Activated HUVECs and Is a Source of PGH2 for Transcellular Metabolism to PGE2 by Tumor Cells.
Neoplasms
Curcumin blocks prostaglandin E2 biosynthesis through direct inhibition of the microsomal prostaglandin E2 synthase-1.
Neoplasms
CYP3A4, CYP2C9 and CYP2B6 expression and ifosfamide turnover in breast cancer tissue microsomes.
Neoplasms
Cytidine 5'-triphosphate-dependent dolichol kinase and dolichol phosphatase activities and levels of dolichyl phosphate in microsomal fractions from highly differentiated human hepatomas.
Neoplasms
Cytochrome P-450 isozyme pattern is related to individual susceptibility to diethylnitrosamine-induced liver cancer in rats.
Neoplasms
Decrease in the activity of hepatic microsomal drug-metabolizing enzymes in tumor-bearing nude mice.
Neoplasms
Decreased lung tumorigenesis in mice genetically deficient in cytosolic phospholipase A2.
Neoplasms
Deep proteogenomic investigations elucidate the NRF2 antioxidant mechanism as a major driving mechanism of lung adenocarcinoma in Asia.
Neoplasms
Defensive nature of Sargassum polycystum (Brown alga) against acetaminophen-induced toxic hepatitis in rats: role of drug metabolizing microsomal enzyme system, tumor necrosis factor-alpha and fate of liver cell structural integrity.
Neoplasms
Demonstration of the transferrin receptor in human breast cancer tissue. Potential marker for identifying dividing cells.
Neoplasms
Denitrosation of the anti-cancer drug 1,3-bis(2-chloroethyl)-1-nitrosourea catalyzed by microsomal glutathione S-transferase and cytochrome P450 monooxygenases.
Neoplasms
Dietary effects of menhaden oil on the growth and membrane lipid composition of rat mammary tumors.
Neoplasms
Dietary ellagic acid reduces the esophageal microsomal metabolism of methylbenzylnitrosamine.
Neoplasms
Dietary lipotropes, hepatic microsomal mixed-function oxidase activities, and in vivo covalent binding of aflatoxin B1 in rats.
Neoplasms
Different sensitivity of two Walker 256 carcinoma lines to cyclophosphamide: correlation with drug distribution, biotransformation and macromolecule binding.
Neoplasms
Differential activation of cyclophosphamide and ifosphamide by cytochromes P-450 2B and 3A in human liver microsomes.
Neoplasms
Differential effects of Walker 256 carcinosarcoma cells growing subcutaneously, intramuscularly, or intraperitoneally on hepatic microsomal mixed-function oxygenase activity.
Neoplasms
Discovery of kinase spectrum selective macrocycle (16E)-14-methyl-20-oxa-5,7,14,26-tetraazatetracyclo[19.3.1.1(2,6).1(8,12)]heptacosa-1(25),2(26),3,5,8(27),9,11,16,21,23-decaene (SB1317/TG02), a potent inhibitor of cyclin dependent kinases (CDKs), Janus kinase 2 (JAK2), and fms-like tyrosine kinase-3 (FLT3) for the treatment of cancer.
Neoplasms
Discovery of pyridone-based histone deacetylase inhibitors: approaches for metabolic stability.
Neoplasms
Displacement by tamoxifen of the estradiol-estrogen receptor binding: a functional assay for breast cancer studies.
Neoplasms
Distribution of microsomal epoxide hydrolase in humans: an immunohistochemical study in normal tissues, and benign and malignant tumours.
Neoplasms
DNA polymerases from intracisternal A-type particles on the mouse plasmacytoma MPC 11.
Neoplasms
Does dienogest influence the inflammatory response of endometriotic cells? A systematic review.
Neoplasms
Drug metabolism in rats with cancer induced by N-nitrosodiethylamine and phenobarbital.
Neoplasms
Effect of a hepatic activation system on the antiproliferative activity of hexamethylmelamine against human tumor cell lines.
Neoplasms
Effect of a zinc-deficient diet on lipid peroxidation in liver and tumor subcellular membranes.
Neoplasms
Effect of different levels of omega-3 and omega-6 fatty acids on azoxymethane-induced colon carcinogenesis in F344 rats.
Neoplasms
Effect of epoxide hydrolase polymorphisms on chromosome aberrations and risk for lung cancer.
Neoplasms
Effect of nonspecific phospholipid transfer protein on cholesterol esterification in microsomes from Morris hepatomas.
Neoplasms
Effect of phenobarbital and other liver monooxygenase modifiers on dimethylnitrosamine-induced alkylation of rat liver macromolecules.
Neoplasms
Effect of pretreatment with phenobarbital or SKF 525A on the toxicity and antitumor activity of lomustine.
Neoplasms
Effect of strain differences and tumor presence on microsomal drug metabolism in the guinea pig: brief communication.
Neoplasms
Effects of chemical inducers on human microsomal epoxide hydrolase in primary hepatocyte cultures.
Neoplasms
Effects of dieldrin, diet, and bedding on enzyme function and tumor incidence in livers of male CF-1 mice.
Neoplasms
Effects of diet and ethanol on the expression and localization of cytochromes P450 2E1 and P450 2C7 in the colon of male rats.
Neoplasms
Effects of interleukin-6 on cytochrome P450-dependent mixed-function oxidases in the rat.
Neoplasms
Effects of long term dietary phenethyl isothiocyanate on the microsomal metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol in F344 rats.
Neoplasms
Effects of microsomal enzyme inducers on thyroid-follicular cell proliferation, hyperplasia, and hypertrophy.
Neoplasms
Effects of partial hepatectomy and dietary phenobarbital on liver and mammary tumorigenesis by two N-hydroxy-N-acylaminobiphenyls in female CD rats.
Neoplasms
Effects of phenobarbital and 3-methylcolanthrene treatment on microsomes of Morris hepatoma 3924-A, tumour-bearing and normal rat liver.
Neoplasms
Effects of phenobarbital, pregnenolone-16alpha-carbonitrile, and propylthiouracil on thyroid follicular cell proliferation.
Neoplasms
Effects of selenium on 7,12-dimethylbenz(a)anthracene-induced mammary carcinogenesis and DNA adduct formation.
Neoplasms
Effects of the antitumor agents from various natural sources on drug-metabolizing system, phagocytic activity and complement system in sarcoma 180-bearing mice.
Neoplasms
EGFR signaling upregulates expression of microsomal prostaglandin E synthase-1 in cancer cells leading to enhanced tumorigenicity.
Neoplasms
Ehrlich's ascites fluid adsorbed over protein A containing Staphylococcus aureus Cowan I produces inhibition of tumor growth.
Neoplasms
Elevated concentrations of mitochondrial peripheral benzodiazepine receptors in ovarian tumors.
Neoplasms
Elevation of de novo ceramide synthesis in tumor masses and the role of microsomal dihydroceramide synthase.
Neoplasms
Enantioselective cytotoxic activity of bromine-substituted analogues of ifosfamide. A microsomal implication.
Neoplasms
Enhanced cancer growth in mice administered daily human-equivalent doses of some H1-antihistamines: predictive in vitro correlates.
Neoplasms
Enhanced drug-metabolizing capacity within liver adjacent to human and rat liver tumors.
Neoplasms
Enhancement of acyl coenzyme A:retinol acyltransferase in rat liver and mammary tumor tissue by retinyl acetate and its competitive inhibition by N-(4-hydroxyphenyl) retinamide.
Neoplasms
Enoximone in contrast to dobutamine improves hepatosplanchnic function in fluid-optimized septic shock patients.
Neoplasms
Enzymology of mitomycin C metabolic activation in tumour tissue. Characterization of a novel mitochondrial reductase.
Neoplasms
Epoxide hydrolase and CYP2C9 polymorphisms, cigarette smoking, and risk of colorectal carcinoma in the Nurses' Health Study and the Physicians' Health Study.
Neoplasms
Epoxide hydrolase genotype and orolaryngeal cancer risk: interaction with GSTM1 genotype.
Neoplasms
Esophageal microsomal metabolism of N-nitrosomethylbenzylamine in the zinc-deficient rat.
Neoplasms
Estrogen synthesizing rare malignant Brenner tumor of the ovary with the presence of progesterone and androgen receptors in the absence of estrogen receptors.
Neoplasms
Ethanol metabolism by a transplantable hepatocellular carcinoma. Role of microsomes and mitochondria.
Neoplasms
Evoked effects of PGE2 and PGA2 on lipid fluidity and Ca2+-stimulated ATPase of Walker-256 tumor microsomal membranes.
Neoplasms
Experiments aiming at demonstrating microsomal drug metabolism in the tumor tissue.
Neoplasms
Expression of class I and II human leukocyte antigens by thyrocytes and lymphocytic infiltration on human thyroid tumors. An immunofluorescence study.
Neoplasms
Expression of cytochrome P-450(17) alpha, 3 beta-hydroxysteroid dehydrogenase/delta 5----4-isomerase, and steroid 5 alpha-reductase in rat H540 Leydig tumor cells.
Neoplasms
Expression of microsomal prostaglandin E synthase-1 in intestinal type gastric adenocarcinoma and in gastric cancer cell lines.
Neoplasms
Functional polymorphisms of the microsomal epoxide hydrolase gene: A reappraisal on a early-onset lung cancer patients series.
Neoplasms
Further studies on effects of a small intestinal microsomal fraction upon transplantable tumors.
Neoplasms
Further studies on the potential contribution of acetaldehyde accumulation and oxidative stress in rat mammary tissue in the alcohol drinking promotion of breast cancer.
Neoplasms
gamma-Glutamyl carboxylase activity in experimental tumor tissues: a biochemical basis for vitamin K dependence of cancer procoagulant.
Neoplasms
Gene Deletion of Microsomal Prostaglandin E Synthase-1 Suppresses Chemically Induced Skin Carcinogenesis.
Neoplasms
Gene expression analysis for predicting gemcitabine sensitivity in pancreatic cancer patients.
Neoplasms
Gene polymorphisms associated with non-alcoholic fatty liver disease and coronary artery disease: a concise review.
Neoplasms
Genetic polymorphism and gene expression of microsomal epoxide hydrolase in non-small cell lung cancer.
Neoplasms
Genetic polymorphisms of cytochrome P450 CYP1A1 (*2A) and microsomal epoxide hydrolase gene, interactions with tobacco-users, and susceptibility to bladder cancer: a study from North India.
Neoplasms
Genetically lowered microsomal epoxide hydrolase activity and tobacco-related cancer in 47,000 individuals.
Neoplasms
Genetics of chronic obstructive pulmonary disease, beyond a1-antitrypsin deficiency.
Neoplasms
Glutathione S-transferase expression in the human testis and testicular germ cell neoplasia.
Neoplasms
Glutathione S-transferase isoenzymes in human renal carcinoma demonstrated by immunohistochemistry.
Neoplasms
Glutathione-related enzymes contribute to resistance of tumor cells and low toxicity in normal organs to artesunate.
Neoplasms
Glutathione-S-transferase and microsomal epoxide hydrolase polymorphism and viral-related hepatocellular carcinoma risk in India.
Neoplasms
Growth inhibition and prostaglandin metabolism in the R3230AC mammary adenocarcinoma by reduced glutathione.
Neoplasms
Haplotypes of Microsomal Epoxide Hydrolase and X-Ray Cross-Complementing Group 1 Genes in Indian Hepatocellular Carcinoma Patients.
Neoplasms
Heat-stimulated nitroreductive bioactivation of the 2-nitroimidazole benznidazole in vitro.
Neoplasms
Hepatic Scaling Factors for In Vitro-In Vivo Extrapolation of Metabolic Drug Clearance in Patients with Colorectal Cancer with Liver Metastasis.
Neoplasms
Heterogeneous nuclear ribonucleoproteins and their interactors are a major class of deregulated proteins in anaplastic astrocytoma: a grade III malignant glioma.
Neoplasms
Hexachlorobenzene is a tumor co-carcinogen and induces alterations in insulin-growth factors signaling pathway in the rat mammary gland.
Neoplasms
High dietary level of synthetic vitamin E on lipid peroxidation, membrane fatty acid composition and cytotoxicity in breast cancer xenograft and in mouse host tissue.
Neoplasms
High-activity microsomal epoxide hydrolase genotypes and the risk of oral, pharynx, and larynx cancers.
Neoplasms
Human hepatic cytochrome P-450 composition as probed by in vitro microsomal metabolism of warfarin.
Neoplasms
Human hepatic microsomal epoxide hydrolase: comparative analysis of polymorphic expression.
Neoplasms
Human melanomas of fibroblast and epithelial morphology differ widely in their ability to synthesize retinyl esters.
Neoplasms
Human ovarian cancer, lymphoma spleen, and bovine milk GlcNAc:beta1,4Gal/GalNAc transferases: two molecular species in ovarian tumor and induction of GalNAcbeta1,4Glc synthesis by alpha-lactalbumin.
Neoplasms
Identification of a novel class of anti-inflammatory compounds with anti-tumor activity in colorectal and lung cancers.
Neoplasms
Identification of peroxisome proliferator-responsive human genes by elevated expression of the peroxisome proliferator-activated receptor alpha in HepG2 cells.
Neoplasms
Immunohistochemical assessment of human microsomal epoxide hydrolase in primary and secondary liver neoplasm: a quantitative approach.
Neoplasms
Immunological identification of a common precursor to arginine vasopressin and neurophysin II synthesized by in vitro translation of bovine hypothalamic mRNA.
Neoplasms
In vitro biosynthesis of human renin and identification of plasma inactive renin as an activation intermediate.
Neoplasms
In vitro cytostatic activity of 8-substituted and tricyclic analogues of acyclovir.
Neoplasms
In vitro prostaglandin H synthase- and monooxygenase-mediated binding of aflatoxin B1 to DNA in guinea-pig tissue microsomes.
Neoplasms
In vivo detection of free radicals induced by diethylnitrosamine in rat liver tissue.
Neoplasms
In vivo effect of chemically induced fibrosarcoma on copper metabolism of liver in mice.
Neoplasms
In-vitro evidence for the regulation of 17,20-lyase activity by cytochrome b5 in adrenocortical adenomas from patients with Cushing's syndrome.
Neoplasms
Incorporation of 35SO4 into endogenous heparin by a microsomal fraction from mast cell tumors.
Neoplasms
Increased estrogen sulfation of estradiol 17beta-D-glucuronide in metastatic tumor rat livers.
Neoplasms
Indole-3-propionic acid, a melatonin-related molecule, protects hepatic microsomal membranes from iron-induced oxidative damage: relevance to cancer reduction.
Neoplasms
Induction of a novel Ca2+-dependent chymotrypsin-like serine protease by tumor promoters in rat livers.
Neoplasms
Induction of colon tumors in 1,2-dimethylhydrazine-resistant Lobund Wistar rats by methylazoxymethanol acetate.
Neoplasms
Inhibition of hypoxia inducible factor-1alpha by dihydroxyphenylethanol, a product from olive oil, blocks microsomal prostaglandin-E synthase-1/vascular endothelial growth factor expression and reduces tumor angiogenesis.
Neoplasms
Inhibition of Leydig tumor cell steroidogenesis by 10-propargylestr-4-ene-3,17-dione, an irreversible aromatase inhibitor.
Neoplasms
Inhibition of tumour promotion in mouse skin by extracts of rooibos (Aspalathus linearis) and honeybush (Cyclopia intermedia), unique South African herbal teas.
Neoplasms
Inhibitory effect of meloxicam, a selective cyclooxygenase-2 inhibitor, and ciglitazone, a peroxisome proliferator-activated receptor gamma ligand, on the growth of human ovarian cancers.
Neoplasms
Inhibitory effects of diallyl sulfide on the metabolism and tumorigenicity of the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in A/J mouse lung.
Neoplasms
Initiation of poly-N-acetyllactosamine chain biosynthesis occurs preferentially on complex multiantennary asparagine-linked oligosaccharides.
Neoplasms
Innate immune reaction in response to seizures: implications for the neuropathology associated with epilepsy.
Neoplasms
Insulin-like growth factor-I receptor expression and localization in benign and malignant rat mammary tumors.
Neoplasms
Intervention of transplantable human mammary carcinoma MX-1 chemotherapy with dietary menhaden oil in athymic mice: increased therapeutic effects and decreased toxicity of cyclophosphamide.
Neoplasms
Intestine-Specific Mttp Deletion Increases the Severity of Experimental Colitis and Leads to Greater Tumor Burden in a Model of Colitis Associated Cancer.
Neoplasms
Intracellular mechanisms underlying lipid accumulation (white opaque substance) in gastric epithelial neoplasms: A pilot study of expression profiles of lipid-metabolism-associated genes.
Neoplasms
Investigation of the rate-determining microsomal reaction of cholesterol biosynthesis from lanosterol in Morris hepatomas and liver.
Neoplasms
Involvement of cytochrome P4503A in catalysis of tamoxifen activation and covalent binding to rat and human liver microsomes.
Neoplasms
Isoforms of protein kinase C and their distribution in human adrenal cortex and tumors.
Neoplasms
Isolation and characterization of a cytochrome P450 of the IIA subfamily from human liver microsomes.
Neoplasms
Kinetic modeling of beta-chloroprene metabolism: I. In vitro rates in liver and lung tissue fractions from mice, rats, hamsters, and humans.
Neoplasms
Knockdown of microsomal glutathione S-transferase 1 inhibits lung adenocarcinoma cell proliferation and induces apoptosis.
Neoplasms
Levels of cytochrome P-450, steroidogenesis and microsomal and cytosolic epoxide hydrolases in normal human adrenal tissue and corresponding tumors.
Neoplasms
Ligands of the antiestrogen binding site block endothelial cell proliferation reversibly.
Neoplasms
LINC00205 modulates the expression of EPHX1 through the inhibition of miR-184 in hepatocellular carcinoma as a ceRNA.
Neoplasms
Lipid composition of glucose-stimulated pancreatic islets and insulin-secreting tumor cells.
Neoplasms
Lipid peroxidation of the microsomal fraction and extracted microsomal lipids from DAB-induced hepatomas.
Neoplasms
Localization of microsomal epoxide hydrolase in normal and neoplastic human kidney.
Neoplasms
Loss of 15-Hydroxyprostaglandin Dehydrogenase Increases Prostaglandin E2 in Pancreatic Tumors.
Neoplasms
Loss of tumor-promoting activity of unleaded gasoline in N-nitrosodiethylamine-initiated ovariectomized B6C3F1 mouse liver.
Neoplasms
Low microsomal epoxide hydrolase expression is associated with bladder carcinogenesis and recurrence.
Neoplasms
Lung cancer susceptibility in relation to combined polymorphisms of microsomal epoxide hydrolase and glutathione S-transferase P1.
Neoplasms
Mechanism of abnormal production of adrenal androgens in patients with adrenocortical adenomas and carcinomas.
Neoplasms
Mechanism of the abnormal vitamin K-dependent gamma-carboxylation process in human hepatocellular carcinomas.
Neoplasms
Mechanisms of induction of cytosolic and microsomal glutathione transferase (GST) genes by xenobiotics and pro-inflammatory agents.
Neoplasms
Melatonin inhibits the growth of DMBA-induced mammary tumors by decreasing the local biosynthesis of estrogens through the modulation of aromatase activity.
Neoplasms
Metabolic genotypes as modulators of asbestos-related pleural malignant mesothelioma risk: a comparison of Finnish and Italian populations.
Neoplasms
Metabolism of dimethylnitrosamine to mutagenic intermediates by kidney microsomal enzymes and correlation with reported host susceptibility to kidney tumors.
Neoplasms
Microsomal aromatase in testicular tumour tissue: increased activity in choriocarcinoma compared to embryonal carcinoma.
Neoplasms
Microsomal epoxide hydrolase (EPHX1), slow (exon 3, 113His) and fast (exon 4, 139Arg) alleles confer susceptibility to squamous cell esophageal cancer.
Neoplasms
Microsomal epoxide hydrolase 1 (EPHX1): Gene, structure, function, and role in human disease.
Neoplasms
Microsomal epoxide hydrolase expression as a predictor of tamoxifen response in primary breast cancer: a retrospective exploratory study with long-term follow-up.
Neoplasms
Microsomal Epoxide Hydrolase Polymorphisms and Haplotypes as Determinants of Hepatitis B Virusand Hepatitis C Virus-related Liver Disease in Indian Population.
Neoplasms
Microsomal fatty acid desaturation and elongation in a human lung carcinoma grown in nude mice.
Neoplasms
Microsomal metabolites of the aryl hydrocarbon hydroxylase and tumour inhibitor 7,8-benzoflavone.
Neoplasms
Microsomal prostaglandin E synthase-1 is involved in multiple steps of colon carcinogenesis.
Neoplasms
Microsomal synthesis of the ether analogs of triacylglycerols. Acyl CoA:alkylacylglycerol and acyl CoA:alk-i-enylacylglycerol acyltransferases in tumors and liver.
Neoplasms
Mismatched effects of receptor interacting protein kinase-3 on hepatic steatosis and inflammation in non-alcoholic fatty liver disease.
Neoplasms
Mitochondrial and microsomal peripheral benzodiazepine receptors in human ovarian cancer xenografts.
Neoplasms
Mode of action analysis for the synthetic pyrethroid metofluthrin-induced rat liver tumors: evidence for hepatic CYP2B induction and hepatocyte proliferation.
Neoplasms
Modifications of flexible nonyl chain and nucleobase head group of (+)-erythro-9-(2's-hydroxy-3's-nonyl)adenine [(+)-EHNA] as adenosine deaminase inhibitors.
Neoplasms
Modulation of peripheral benzodiazepine receptor density by testosterone in Dunning G prostatic adenocarcinoma.
Neoplasms
Modulation of thiotepa antitumor activity in vivo by alteration of liver cytochrome P450-catalyzed drug metabolism.
Neoplasms
Monoclonal antibody recognizing a determinant on type 2 chain blood group A and B oligosaccharides detects oncodevelopmental changes in azoxymethane-induced rat colon tumors and human colon cancer cell lines.
Neoplasms
Monooxygenase system in Guerins carcinoma of rats under conditions of ?-3 polyunsaturated fatty acids administration.
Neoplasms
Monooxygenase, epoxide hydrolase, and glutathione-S-transferase activities in human lung. Variation between groups of bronchogenic carcinoma and non-cancer patients and interindividual differences.
Neoplasms
Mouse liver tumors and microsomal enzyme-inducing drugs: experimental and clinical perspectives with phenobarbital.
Neoplasms
mPGES-1-expressing bone marrow-derived cells enhance tumor growth and angiogenesis in mice.
Neoplasms
n-3 Polyunsaturated fatty acids for the management of alcoholic liver disease: A critical review.
Neoplasms
NAD(P)H:quinone oxidoreductase-1-dependent and -independent cytotoxicity of potent quinone Cdc25 phosphatase inhibitors.
Neoplasms
NAD+-dependent 15-hydroxyprostaglandin dehydrogenase regulates levels of bioactive lipids in non-small cell lung cancer.
Neoplasms
New actinomycin D analogues as superior chemotherapeutic agents against primary and advanced colon tumors and colon xenografts in nude mice.
Neoplasms
Non-uniformity of Changes in Drug-Metabolizing Enzymes and Transporters in Liver Cirrhosis: Implications for Drug Dosage Adjustment.
Neoplasms
Novel retinoic acid metabolism blocking agents endowed with multiple biological activities are efficient growth inhibitors of human breast and prostate cancer cells in vitro and a human breast tumor xenograft in nude mice.
Neoplasms
Nuclear heme oxygenase-1 (HO-1) modulates subcellular distribution and activation of Nrf2, impacting metabolic and anti-oxidant defenses.
Neoplasms
O-Glycosylation and cellular differentiation in a subpopulation of mucin-secreting HT-29 cell line.
Neoplasms
Optimization of the anti-cancer activity of phosphatidylinositol-3 kinase pathway inhibitor PITENIN-1: switching a thiourea with 1,2,3-triazole.
Neoplasms
Oxidative biotransformation of benzo(a)pyrene by human lung microsomal fractions prepared from surgical specimens.
Neoplasms
Particular cytochrome P-450-dependent steroid metabolism: a new class of mouse liver tumor markers.
Neoplasms
Peripheral benzodiazepine receptors in androgen sensitive dunning rat prostatic adenocarcinoma.
Neoplasms
PGE2 and PGA2 affect the allosteric properties and the activities of calmodulin-dependent guanylate cyclase and Ca2+-stimulated ATPase of Walker-256 tumour microsomal membranes.
Neoplasms
Pharmacokinetics of 5-fluorouracil in mutant Nagase analbuminemic rats: faster metabolism of 5-fluorouracil via CYP1A.
Neoplasms
Phenobarbital does not promote hepatic tumorigenesis in a twenty-six-week bioassay in p53 heterozygous mice.
Neoplasms
Phenobarbital, beta-naphthoflavone, clofibrate, and pregnenolone-16alpha-carbonitrile do not affect hepatic thyroid hormone UDP-glucuronosyl transferase activity, and thyroid gland function in mice.
Neoplasms
Photoaffinity labeling of peripheral benzodiazepine receptors in R-3327 Dunning prostatic tumors.
Neoplasms
Physiological effects of cabbage with reference to its potential as a dietary cancer-inhibitor and its use in ancient medicine.
Neoplasms
Polymorphic enzymes of xenobiotic metabolism as modulators of acquired P53 mutations in bladder cancer.
Neoplasms
Polymorphisms of N-acetyltransferases, glutathione S-transferases, microsomal epoxide hydrolase and sulfotransferases: influence on cancer susceptibility.
Neoplasms
Possible role of riboflavin deficiency in epithelial neoplasia. 3. Induction of microsomal aryl hydrocarbon hydroxylase.
Neoplasms
Processing of placental peptide hormones synthesized in lysates containing membranes derived from tunicamycin-treated ascites tumor cells.
Neoplasms
Profiling the progression of cancer: separation of microsomal proteins in MCF10 breast epithelial cell lines using nonporous chromatophoresis.
Neoplasms
Prolactin binding components in prostatic cancer tissue specimens obtained by TURP.
Neoplasms
Prostaglandin concentrations and prostaglandin synthetase activity in N-nitrosomethylurea-induced rat mammary adenocarcinoma.
Neoplasms
Protective role of vanadium in the survival of hosts during the growth of a transplantable murine lymphoma and its profound effects on the rates and patterns of biotransformation.
Neoplasms
Proteomic Quantification of Changes in Abundance of Drug-Metabolizing Enzymes and Drug Transporters in Human Liver Cirrhosis: Different Methods, Similar Outcomes.
Neoplasms
Proteomics-Based Characterization of miR-574-5p Decoy to CUGBP1 Suggests Specificity for mPGES-1 Regulation in Human Lung Cancer Cells.
Neoplasms
Purification and characterization of a lysosomal form and a variant form of beta-glucuronidase from the rat basophil leukaemia tumour.
Neoplasms
Putative EPHX1 Enzyme Activity Is Related with Risk of Lung and Upper Aerodigestive Tract Cancers: A Comprehensive Meta-Analysis.
Neoplasms
Quantitative assessment of the influence of EPHX1 gene polymorphisms and cancer risk: a meta-analysis with 94,213 subjects.
Neoplasms
Rat ventral prostate microsomal biotransformation of ethanol to acetaldehyde and 1-hydroxyethyl radicals: its potential contribution to prostate tumor promotion.
Neoplasms
Receptors characterization of intraperitoneally N-nitroso-N-methylurea-induced mammary tumors in rats.
Neoplasms
Recombinant tumor necrosis factor depresses cytochrome P450-dependent microsomal drug metabolism in mice.
Neoplasms
Reduction of dihydrodiol dehydrogenase expression in resected hepatocellular carcinoma.
Neoplasms
Reduction of N-nitrosodiethylamine carcinogenesis in rats by lipotrope or amino acid supplementation of a marginally deficient diet.
Neoplasms
Reductive metabolism and alkylating activity of mitomycin C induced by rat liver microsomes.
Neoplasms
Regulation of expression of male-specific rat liver microsomal 3 beta-hydroxysteroid dehydrogenase.
Neoplasms
Regulation of Human Microsomal Prostaglandin E Synthase-1 by IL-1? requires a Distal Enhancer Element with a Unique Role for C/EBP?
Neoplasms
Relationship between the microsomal epoxide hydrolase and the hepatocellular transport of bile acids and xenobiotics.
Neoplasms
Retention mechanism of hypoxia selective nuclear imaging/radiotherapeutic agent cu-diacetyl-bis(N4-methylthiosemicarbazone) (Cu-ATSM) in tumor cells.
Neoplasms
Revealing the effect of 6-gingerol, 6-shogaol and curcumin on mPGES-1, GSK-3? and ?-catenin pathway in A549 cell line.
Neoplasms
Reversal of cytochrome P-4501A1 and P-450-EF expression in MCA-C3H/10T1/2 cell-derived tumors as compared to cultured cells.
Neoplasms
Role of beta-carotene on the changes in activity patterns and levels of biotransforming enzymes in transplantable murine lymphoma.
Neoplasms
Role of lipid transfer proteins in the abnormal lipid content of Morris hepatoma mitochondria and microsomes.
Neoplasms
Role of metabolism in effects of diflubenzuron on growth of B16 melanomas in mice.
Neoplasms
Role of NQO1C609T and EPHX1 gene polymorphisms in the association of smoking and alcohol with sporadic distal colorectal adenomas: results from the UKFSS Study.
Neoplasms
Skin and salivary gland carcinogenicity of 7,12-dimethylbenz[a]anthracene is equivalent in the presence or absence of aryl hydrocarbon receptor.
Neoplasms
Src tyrosine kinase mediates stimulation of Raf-1 and mitogen-activated protein kinase by the tumor promoter thapsigargin.
Neoplasms
Stauntoside B inhibits macrophage activation by inhibiting NF-?B and ERK MAPK signalling.
Neoplasms
Steroid 21-hydroxylase and 17 alpha-hydroxylase in microsomal fraction of functioning adrenocortical tumors.
Neoplasms
Steroid metabolism in normal mammary gland and in the dimethylbenzanthracene-induced mammary tumor of rats.
Neoplasms
Structures, biogenesis, and biological activities of pyrano[4,3-c]isochromen-4-one derivatives from the Fungus Phellinus igniarius.
Neoplasms
Studies of the effects of treatment with 5-flourouracil alone and in combination with either cyclophosphamide, methotrexate, or methyl-CCNU on hepatic drug-metabolizing enzymes in murine L1210 leukemia.
Neoplasms
Studies on 18F-labeled pyrimidines III. Biochemical investigation of 18F-labeled pyrimidines and comparison with 3H-deoxythymidine in tumor-bearing rats and mice.
Neoplasms
Studies on lipid peroxidation in normal and tumour tissues. The Novikoff rat liver tumour.
Neoplasms
Studies on the mode of action for thyroid gland tumor promotion in rats by phenobarbital.
Neoplasms
Study of relationship between allogeneic transplantability of tumors and their effects on drug-metabolizing system in rats.
Neoplasms
Subcellular and extracellular localization of specific binding sites for triphenylethylene antiestrogens in human breast cancer.
Neoplasms
Superoxide dismutase content and microsomal lipid composition of tumours with different growth rates.
Neoplasms
Symposium overview: the role of genetic polymorphism and repair deficiencies in environmental disease.
Neoplasms
Synthesis and antitumor activity of 6-trifluoromethylcyclophosphamide and related compounds.
Neoplasms
Synthesis and biological evaluation of novel myrtucommulones and structural analogues that target mPGES-1 and 5-lipoxygenase.
Neoplasms
The chemopreventive properties of chlorogenic acid reveal a potential new role for the microsomal glucose-6-phosphate translocase in brain tumor progression.
Neoplasms
The effect of a pituitary mammotropic tumor on hepatic microsomal drug metabolism in the rat.
Neoplasms
The essential role of microsomal deacetylase activity in the metabolic activation, DNA-(deoxyguanosin-8-yl)-2-aminofluorene adduct formation and initiation of liver tumors by N-hydroxy-2-acetylaminofluorene in the livers of infant male B6C3F1 mice.
Neoplasms
The lipid composition of highly differentiated human hepatomas, with special reference to fatty acids.
Neoplasms
The mode of action of cytotoxic and antitumor 1-nitroacridines. II. In vivo enzyme-mediated covalent binding of a 1-nitroacridine derivative, Ledakrin or Nitracrine, with dna and other macromolecules of mammalian or bacterial cells.
Neoplasms
The possible roles of membrane organization in the activity of androgen biosynthetic enzymes associated with normal or tumorous mouse Leydig cell microsomes.
Neoplasms
The relationship between metabolism, DNA binding, and carcinogenicity of 15,16-dihydro-11-methylcyclopenta(alpha)phenanthren-17-one in the presence of a microsomal enzyme inhibitor.
Neoplasms
The relationship of the cyclic nucleotide system to inhibition of hepatic drug metabolism in Walker 256 carcinoma-bearing rats.
Neoplasms
The role of acyldihydroxyacetone phosphate, reduced nicotinamide adenine dinucleotide, and reduced nicotinamide adenine dinucleotide phosphate in the biosynthesis of O-alkyl glycerolipids by microsomal enzymes of Ehrlich ascites tumor.
Neoplasms
The role of cytochrome P450 and cytochrome P450 reductase in the reductive bioactivation of the novel benzotriazine di-N-oxide hypoxic cytotoxin 3-amino-1,2,4-benzotriazine-1,4-dioxide (SR 4233, WIN 59075) by mouse liver.
Neoplasms
The role of delta-6- and delta-9-desaturase in the fatty acid metabolism of hepatomas with different growth rate.
Neoplasms
The SANT2 domain of the murine tumor cell DnaJ-like protein 1 human homologue interacts with alpha1-antichymotrypsin and kinetically interferes with its serpin inhibitory activity.
Neoplasms
The significance of hepatic microsomal enzyme induction and altered thyroid function in rats: implications for thyroid gland neoplasia.
Neoplasms
The utilization of in vitro mutagenesis techniques to explain strain, age and sex related differences in dimethylnitrosamine tumor susceptibilities in mice.
Neoplasms
Tin-protoporphyrin inhibits heme oxygenase and prevents the decline in hepatic heme and cytochrome P-450 contents produced in nude mice by tumor transplantation.
Neoplasms
Tissue and species specificity of the microsomal metabolism of N-nitrosomethylbenzylamine.
Neoplasms
Translocation of phosphatidate phosphohydrolase from the cytosol to microsomal membranes in thioacetamide-induced liver tumours in rats.
Neoplasms
Tumor microsomal metabolism of the food toxicant, benzo(a)pyrene, in Apc( Min ) mouse model of colon cancer.
Neoplasms
Tumor promoter-stimulated translocation of glucose transport system in mouse embryo fibroblast Swiss 3T3 cell.
Neoplasms
Weight-of-evidence versus strength-of-evidence in toxicologic hazard identification: Di(2-ethylhexyl)phthalate (DEHP).
Neoplasms
Xanthones as inhibitors of microsomal lipid peroxidation and TNF-alpha induced ICAM-1 expression on human umbilical vein endothelial cells (HUVECs).
Neoplasms
Xenobiotic metabolizing enzymes in genetically and chemically initiated mouse liver tumors.
Neoplasms
Zonated expression of cytokines in rat liver: effect of chronic ethanol and the cytochrome P450 2E1 inhibitor, chlormethiazole.
Neoplasms
[Activity of 5-alpha- and 5-beta-steroid reductases in subcellular liver structures from rats bearing Walker carcinosarcoma]
Neoplasms
[Cellular mechanisms of induction of apoptosis in human erythroleukaemic K562 cells line treated by quinoline-N-oxide derivatives]
Neoplasms
[Changes in phospholipid composition in rat liver microsomes and mitochondria under chemical carcinogenesis]
Neoplasms
[Cytochrome P-450 and aryl hydroxylase activity in cells of a long-term transplantable tumor]
Neoplasms
[Differing microsomal monoxygenase activity in the cells of ascitic and solid forms of transplantable tumors]
Neoplasms
[Effect of liposomal antitumor preparation 5,6-benzocoumarin-5-uracil on intensity of free-radical processes in the liver microsomes and tumor cells of rats with transplanted Guerin's carcinoma]
Neoplasms
[Effect of liposomal antitumor preparation 5-(5',6'-benzocoumarin-3')-methylaminouracil hydrobromide on cytochrome P-450 in the microsomal liver fraction of tumor bearing rats]
Neoplasms
[Effect of low doses of x-ray irradiation on the liver detoxication system in rats with transplanted Guerin's carcinoma].
Neoplasms
[Effect of microsomal fraction of transplantable neoplasm on regeneration of sensory nerves]
Neoplasms
[Effect of pregnenolone-16 -carbonitrile on microsomal enzyme activity and hepatic ultrastructure in a rat bearing a Walker tumor]
Neoplasms
[Effect of thyroid hormones on the modulation of genetic expression of liver cytosolic malic enzyme, in rats poisoned with hexachlorobenzene]
Neoplasms
[Functional activity of NADH-dependent reductase system in the liver microsomal fraction and Guerin's carcinoma in rats exposed to preliminary irradiation].
Neoplasms
[Metabolism and distribution of phosphatidylcholine in membranes of normal and tumor cells]
Neoplasms
[Microsomal N-acetyl-glucosaminyl-transferases activity in BALB/c mice infected with mouse mammary tumor virus (M-MTV) (author's transl)]
Neoplasms
[Rat microsomal glutathione S-transferase 1 alters cytotoxic effects of chlorambucil on PC-3, K562, HepG2 and P388D1 cell lines]
Neoplasms
[Relation Between microsomal epoxide hydrolase polymorphism and susceptibility to ovarian epithelial cancer]
Neoplasms
[Subcellular particles in tumors. II. Analysis of mitochondrial and microsomal fractions in hepatoma HW by isopycnic centrifugation]
Neoplasms
[The induction of Guerin's carcinoma cytochrome p450 hydroxylase activity by retinoids].
Neoplasms
[The role of pyridine nucleotide cofactors in the reaction of microsomal N-demethylation under normal conditions and in tumor pathology]
Neoplasms, Germ Cell and Embryonal
Glutathione S-transferase expression in the human testis and testicular germ cell neoplasia.
Nephritis, Hereditary
Antithyroid and antiadrenal autoantibodies in antiglomerular basement membrane disease, thin basement membrane disease and Alport syndrome.
Nephritis, Hereditary
Asymptomatic autoimmune thyroiditis and thyroid dysfunction in Alport's syndrome. A report of three families.
Nephrolithiasis
[Lipid peroxidation and Ca-dependent ATPase activity in the microsomal fraction of renal tissue in patients with nephrolithiasis and chronic pyelonephritis]
Nervous System Diseases
Elucidation of plasma protein binding, blood partitioning, permeability, CYP phenotyping and CYP inhibition studies of Withanone using validated UPLC method: An active constituent of neuroprotective herb Ashwagandha.
Neuralgia
Ellagic acid enhances the antinociceptive action of carbamazepine in the acetic acid writhing test with mice.
Neuralgia
Tipepidine enhances the antinociceptive-like action of carbamazepine in the acetic acid writhing test.
Neuroblastoma
Calcium Ions Stimulate the Hyperphosphorylation of Tau by Activating Microsomal Prostaglandin E Synthase 1.
Neuroblastoma
Differential expression and regulation of ryanodine receptor and myo-inositol 1,4,5-trisphosphate receptor Ca2+ release channels in mammalian tissues and cell lines.
Neuroblastoma
Effects of neuropathic and non-neuropathic isomers of tricresyl phosphate and their microsomal activation on the production of axon-like processes by differentiating mouse N2a neuroblastoma cells.
Neuroblastoma
Evidence for a GTP-dependent increase in membrane permeability for calcium in NG108-15 microsomes.
Neuroblastoma
Phosphorylation at serine 31 targets tyrosine hydroxylase to vesicles for transport along microtubules.
Neurocutaneous Syndromes
Clinical, biochemical and molecular genetic characteristics of 19 patients with the Sjögren-Larsson syndrome.
Neurocutaneous Syndromes
Defective metabolism of leukotriene B4 in the Sjögren-Larsson syndrome.
Neurocutaneous Syndromes
MRI and 1H-MRS findings of three patients with Sjögren-Larsson syndrome.
Neuroinflammatory Diseases
Anti-inflammatory role of microsomal prostaglandin E synthase-1 in a model of neuroinflammation.
Neurotoxicity Syndromes
Interaction between smoking and glutathione S-transferase polymorphisms in solvent-induced chronic toxic encephalopathy.
Neurotoxicity Syndromes
[The role of smoking and metabolic enzyme polymorphisms in the organic solvent induced chronic encephalopathy].
Newcastle Disease
Translation and membrane insertion of the hemagglutinin-neuraminidase glycoprotein of Newcastle disease virus.
Non-alcoholic Fatty Liver Disease
(13C)-Methacetin breath test provides evidence of subclinical liver dysfunction linked to fat storage but not lifestyle.
Non-alcoholic Fatty Liver Disease
Analysis of hepatic genes involved in the metabolism of fatty acids and iron in nonalcoholic fatty liver disease.
Non-alcoholic Fatty Liver Disease
Association of Polymorphisms in Glutamate-Cysteine Ligase Catalytic Subunit and Microsomal Triglyceride Transfer Protein Genes with Nonalcoholic Fatty Liver Disease.
Non-alcoholic Fatty Liver Disease
Association of polymorphisms of glutamate-cystein ligase and microsomal triglyceride transfer protein genes in non-alcoholic fatty liver disease.
Non-alcoholic Fatty Liver Disease
Correlation between MTP -493G>T polymorphism and non-alcoholic fatty liver disease risk: a meta-analysis.
Non-alcoholic Fatty Liver Disease
CYP2E1 and CYP4A as microsomal catalysts of lipid peroxides in murine nonalcoholic steatohepatitis.
Non-alcoholic Fatty Liver Disease
Effects of insulin resistance and hepatic lipid accumulation on hepatic mRNA expression levels of apoB, MTP and L-FABP in non-alcoholic fatty liver disease.
Non-alcoholic Fatty Liver Disease
Gene polymorphisms associated with non-alcoholic fatty liver disease and coronary artery disease: a concise review.
Non-alcoholic Fatty Liver Disease
Genetic polymorphisms in non-alcoholic fatty liver disease: Interleukin-6-174G/C polymorphism is associated with non-alcoholic steatohepatitis.
Non-alcoholic Fatty Liver Disease
Hepatic cytochrome P450 enzyme alterations in humans with progressive stages of nonalcoholic fatty liver disease.
Non-alcoholic Fatty Liver Disease
Impact of cholesterol metabolism and the LXRalpha-SREBP-1c pathway on nonalcoholic fatty liver disease.
Non-alcoholic Fatty Liver Disease
Induction of microsomal triglyceride transfer protein expression is a candidate mechanism by which ezetimibe therapy might exert beneficial effects in patients with nonalcoholic steatohepatitis.
Non-alcoholic Fatty Liver Disease
Involvement of microsomal triglyceride transfer protein in nonalcoholic steatohepatitis in novel spontaneous mouse model.
Non-alcoholic Fatty Liver Disease
Liver breath tests non-invasively predict higher stages of non-alcoholic steatohepatitis.
Non-alcoholic Fatty Liver Disease
Long-term combination therapy of ezetimibe and acarbose for non-alcoholic fatty liver disease.
Non-alcoholic Fatty Liver Disease
Membrane bound diacylglycerols explain the dissociation of hepatic insulin resistance from steatosis in MTTP-/- mice.
Non-alcoholic Fatty Liver Disease
Microsomal triglyceride transfer protein and nonalcoholic fatty liver disease.
Non-alcoholic Fatty Liver Disease
Modulation of xenobiotic nuclear receptors in high-fat diet induced non-alcoholic fatty liver disease.
Non-alcoholic Fatty Liver Disease
MTP -493G/T Polymorphism and Susceptibility to Nonalcoholic Fatty Liver Disease: A Meta-Analysis.
Non-alcoholic Fatty Liver Disease
n-3 Polyunsaturated fatty acids for the management of alcoholic liver disease: A critical review.
Non-alcoholic Fatty Liver Disease
Nonalcoholic steatohepatitis (NASH) in ob/ob mice treated with yo jyo hen shi ko (YHK): effects on peroxisome proliferator-activated receptors (PPARs) and microsomal triglyceride transfer protein (MTP).
Non-alcoholic Fatty Liver Disease
Pathogenesis and significance of hepatitis C virus steatosis: an update on survival strategy of a successful pathogen.
Non-alcoholic Fatty Liver Disease
Plasma free choline is a novel non-invasive biomarker for early-stage non-alcoholic steatohepatitis: A multi-center validation study.
Non-alcoholic Fatty Liver Disease
Polymorphism in microsomal triglyceride transfer protein: a link between liver disease and atherogenic postprandial lipid profile in NASH?
Non-alcoholic Fatty Liver Disease
Polymorphisms of microsomal triglyceride transfer protein gene and phosphatidylethanolamine N-methyltransferase gene in alcoholic and nonalcoholic fatty liver disease in Koreans.
Non-alcoholic Fatty Liver Disease
Prevention Mechanism of 2,3,5,4'-Tetrahydroxy-stilbene-2-O-?-D-glucoside on Lipid Accumulation in Steatosis Hepatic L-02 Cell.
Non-alcoholic Fatty Liver Disease
Proteomic Quantification of Changes in Abundance of Drug-Metabolizing Enzymes and Drug Transporters in Human Liver Cirrhosis: Different Methods, Similar Outcomes.
Non-alcoholic Fatty Liver Disease
Re-evaluation of fatty acid metabolism-related gene expression in nonalcoholic fatty liver disease.
Non-alcoholic Fatty Liver Disease
Relationship Between Nonalcoholic Fatty Liver Disease Susceptibility Genes and Coronary Artery Disease.
Non-alcoholic Fatty Liver Disease
The association between SNPs rs1800591 and rs3816873 of the MTTP gene and nonalcoholic fatty liver disease: A meta-analysis.
Non-alcoholic Fatty Liver Disease
The role of ¹³C-methacetin breath test for the non-invasive evaluation of nonalcoholic fatty liver disease.
Obesity
A novel autophagy enhancer as a therapeutic agent against metabolic syndrome and diabetes.
Obesity
Altered activity of cytochrome P450 in alcoholic fatty liver exposed to ischemia/reperfusion.
Obesity
Biologic activity of dirlotapide, a novel microsomal triglyceride transfer protein inhibitor, for weight loss in obese dogs.
Obesity
Cardiac expression of microsomal triglyceride transfer protein is increased in obesity and serves to attenuate cardiac triglyceride accumulation.
Obesity
Cardiomyocyte Regulation of Systemic Lipid Metabolism by the Apolipoprotein B-Containing Lipoproteins in Drosophila.
Obesity
Effect of genetic obesity and experimental diabetes on hepatic microsomal mixed function oxidase activities.
Obesity
Hepatic cholesterol metabolism in obesity: activity of microsomal 3-hydroxy-3-methylglutaryl coenzyme A reductase.
Obesity
Human Resistin Stimulates Hepatic Overproduction of Atherogenic ApoB-Containing Lipoprotein Particles by Enhancing ApoB Stability and Impairing Intracellular Insulin Signaling.
Obesity
Impact of Obesity on Ovotoxicity Induced by 7,12-dimethylbenz[a]anthracene in Mice.
Obesity
Insulin degradation. XVIII. On the regulation of glutathione-insulin transhydrogenase in the hyperglycemic obese (ob/ob) mouse.
Obesity
JTT-130, a novel intestine-specific inhibitor of microsomal triglyceride transfer protein, suppresses high fat diet-induced obesity and glucose intolerance in Sprague-Dawley rats.
Obesity
Mechanism of action of hypoglycemic effects of an intestine-specific inhibitor of microsomal triglyceride transfer protein (MTP) in obese rats.
Obesity
Mechanisms underlying hypertriglyceridemia in rats with monosodium L-glutamate-induced obesity: evidence of XBP-1/PDI/MTP axis activation.
Obesity
Mice subjected to aP2-Cre mediated ablation of microsomal triglyceride transfer protein are resistant to high fat diet induced obesity.
Obesity
Obesity as a risk factor for drug-induced organ injury. VI. Increased hepatic P450 concentration and microsomal ethanol oxidizing activity in the obese overfed rat.
Obesity
Octreotide promotes weight loss via suppression of intestinal MTP and apoB48 expression in diet-induced obesity rats.
Obesity
PPAR/RXR Regulation of Fatty Acid Metabolism and Fatty Acid omega-Hydroxylase (CYP4) Isozymes: Implications for Prevention of Lipotoxicity in Fatty Liver Disease.
Obesity
Progressive obesity alters ovarian insulin, phosphatidylinositol-3 kinase, and chemical metabolism signaling pathways and potentiates ovotoxicity induced by phosphoramide mustard in mice.
Obesity
Progressive obesity alters ovarian insulin, phosphatidylinositol-3 kinase, and chemical metabolism signaling pathways and potentiates ovotoxicity induced by phosphoramide mustard in mice.
Obesity
Regulation of putative fatty acid transporters and Acyl-CoA synthetase in liver and adipose tissue in ob/ob mice.
Obesity, Abdominal
Molecular screening of the microsomal triglyceride transfer protein: association between polymorphisms and both abdominal obesity and plasma apolipoprotein B concentration.
Obesity, Abdominal
Visceral obesity and hyperinsulinemia modulate the impact of the microsomal triglyceride transfer protein -493G/T polymorphism on plasma lipoprotein levels in men.
Optic Atrophy, Hereditary, Leber
Genetic variants of TP53 and EPHX1 in Leber's hereditary optic neuropathy and their relationship to age at onset.
Optic Nerve Diseases
Genetic variants of TP53 and EPHX1 in Leber's hereditary optic neuropathy and their relationship to age at onset.
Oral Submucous Fibrosis
High incidence of autoantibodies in Taiwanese patients with oral submucous fibrosis.
Oropharyngeal Neoplasms
High-activity microsomal epoxide hydrolase genotypes and the risk of oral, pharynx, and larynx cancers.
Osteoarthritis
Antithyroid-antibody activity in the snyovial fluid of patients with various arthritides.
Osteomyelitis
[The state of the microsomal oxidative system in the liver of rats with acute osteomyelitis of the mandible]
Osteosarcoma
Immunohistochemical Expression of COX-2, mPGES and EP2 Receptor in Normal and Reactive Canine Bone and in Canine Osteosarcoma.
Osteosarcoma
Purification and biochemical characterization of a virus-specific reverse transcriptase from human osteosarcoma tissue.
Ovarian Neoplasms
Association between EPHX1 polymorphism rs1051740 and the risk of ovarian cancer: a meta-analysis.
Ovarian Neoplasms
Microsomal epoxide hydrolase polymorphism and susceptibility to ovarian cancer.
Ovarian Neoplasms
Microsomal epoxide hydrolase polymorphism as a risk factor for ovarian cancer.
Ovarian Neoplasms
Microsomal epoxide hydrolase polymorphisms and risk for advanced colorectal adenoma.
Ovarian Neoplasms
Mitochondrial and microsomal peripheral benzodiazepine receptors in human ovarian cancer xenografts.
Ovarian Neoplasms
Overexpression of cytochrome P450 1A1 and its novel spliced variant in ovarian cancer cells: alternative subcellular enzyme compartmentation may contribute to carcinogenesis.
Ovarian Neoplasms
Polymorphisms of N-acetyltransferases, glutathione S-transferases, microsomal epoxide hydrolase and sulfotransferases: influence on cancer susceptibility.
Ovarian Neoplasms
Proteins associated with Cisplatin resistance in ovarian cancer cells identified by quantitative proteomic technology and integrated with mRNA expression levels.
Ovarian Neoplasms
Shotgun glycopeptide capture approach coupled with mass spectrometry for comprehensive glycoproteomics.
Ovarian Neoplasms
The microsomal epoxide hydrolase Tyr113His polymorphism: association with risk of ovarian cancer.
Ovarian Neoplasms
Xenobiotic-Metabolizing gene polymorphisms and ovarian cancer risk.
Pancreatic Diseases
The role of epoxide hydrolase Y113H gene variant in pancreatic diseases.
Pancreatic Neoplasms
Expression analysis of the prostaglandin E2 production pathway in human pancreatic cancers.
Pancreatitis
Glutathione S-transferase activity in the liver in acute pancreatitis at various terms of disease and during treatment with inducers.
Pancreatitis
Severe hypertriglyceridemia with pancreatitis: thirteen years' treatment with lomitapide.
Pancreatitis, Chronic
Up-regulation of cytochrome P450 1A2, 2C9, and 2E1 in chronic pancreatitis.
Pancytopenia
Leopard-like retinopathy and severe early-onset portal hypertension expand the phenotype of KARS1-related syndrome: a case report.
Papilloma
Human papillomavirus detection in histologic samples of multifocal epithelial hyperplasia: a novel demographic presentation.
Paralysis
Alteration of Hepatic microsomal enzyme systems and the lethal action of non-steroidal anti-arthritic drugs in acute and chronic models of inflammation.
Paralysis
Cell-free synthesis of functional human epidermal growth factor receptor: Investigation of ligand-independent dimerization in Sf21 microsomal membranes using non-canonical amino acids.
Paralysis
Effect of thymectomy on zoxazolamine paralysis and metabolism in untreated and (PCN) pregnenolone-16alpha-carbonitril- or ACTH-pretreated rats.
Paralysis
Effects of mixed-function oxidase modifiers on neurotoxicity of acrylamide in rats.
Paralysis
Inhibitory effect of propylthiouracil-induced hypothyroidism in rat on oxidative drug metabolism.
Paralysis
Structure-activity relations for methylenedioxyphenyl and related compounds on hepatic microsomal enzyme function, as measured by prolongation of hexobarbital narcosis and zoxazolamine paralysis in mice.
Paralysis
Thiram-induced disturbance of microsomal phospholipid bioformation and phospholipid fatty acid pattern.
Paraparesis, Spastic
Phenotypic variability among adult siblings with Sjögren-Larsson syndrome.
Parasitemia
Chagas' disease: a clinical, parasitological, immunological, and pathological study in rabbits.
Parasitemia
Effect of Plasmodium berghei infection and chloroquine on the hepatic drug metabolizing system of mice.
Parkinson Disease
Cytochrome P450 isozymes catalyzing 4-hydroxylation of parkinsonism-related compound 1,2,3,4-tetrahydroisoquinoline in rat liver microsomes.
Parkinson Disease
Cytochrome P450-dependent metabolism of l-deprenyl in monkey (Cercopithecus aethiops) and C57BL/6 mouse brain microsomal preparations.
Parkinson Disease
Employing in vitro metabolism to guide design of F-labelled PET probes of novel ?-synuclein binding bifunctional compounds.
Parkinson Disease
Genetic polymorphisms of microsomal and soluble epoxide hydrolase and the risk of Parkinson's disease.
Parkinson Disease
In vitro confirmation of selegiline N-oxidation by flavin-containing monooxygenase in rat microsome using LC-ESI MS.
Parkinson Disease
l-Deprenyl metabolism by the cytochrome P450 system in monkey (Cercopithecus aethiops) liver microsomes.
Parkinsonian Disorders
Metabolism of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in mouse liver preparations.
Peptic Ulcer
Blood group activities in water-soluble glycoproteins and in microsomal fractions of gastric mucosa in peptic ulcer and gastric cancer patients.
Peptic Ulcer
[The effect of cimetidine and gastrozepin on liver function and the pharmacotherapy of "hepatogenous" gastroduodenal ulcers and erosions]
Peritonitis
Effect of bile on liver function tests in experimental E. coli peritonitis in the rat.
Peritonitis
Peptidomimetic C5a receptor antagonists with hydrophobic substitutions at the C-terminus: increased receptor specificity and in vivo activity.
Peritonitis
[Clinical and experimental research on the drug-metabolizing function of the liver in peritonitis]
Peritonitis
[The state of the microsomal oxidative system in the rat liver during fecal peritonitis]
Persistent Infection
Microsomal autoantibodies in chronic infection with the HBsAg associated delta (delta) agent.
Persistent Infection
Polymorphisms of microsomal triglyceride transfer protein in different hepatitis B virus-infected patients.
Pharyngeal Neoplasms
CYP1A1, mEH, and GSTM1 Polymophisms and Risk of Oral and Pharyngeal Cancer: A Spanish Case-Control Study.
Pharyngitis
Upper-airway obstruction and prolonged recovery from anesthesia following intranasal clotrimazole administration.
Pheochromocytoma
Identification of inositol 1,4,5-trisphosphate binding in human pheochromocytoma.
phosphatidylcholine-sterol o-acyltransferase deficiency
Enzymic esterification of cholesterol in rat intestinal mucosa catalyzed by acyl-CoA: cholesterol acyltransferase.
Photosensitivity Disorders
Acridine orange-mediated photodamage of microsomal- and lysosomal fractions.
Photosensitivity Disorders
Destruction of microsomal cytochrome P-450 by reactive oxygen species generated during photosensitization of hematoporphyrin derivative.
Photosensitivity Disorders
Role of active oxygen species in the photodestruction of microsomal cytochrome P-450 and associated monooxygenases by hematoporphyrin derivative in rats.
Photosensitivity Disorders
Studies on the nature of in vitro and in vivo photosensitization reactions by psoralens and porphyrins.
Photosensitivity Disorders
[Photosensitization of mitochondrial and microsomal enzymes by hematoporphyrin derivative in vitro]
Pituitary ACTH Hypersecretion
Steroid 21-hydroxylase and 17 alpha-hydroxylase in microsomal fraction of functioning adrenocortical tumors.
Pituitary Neoplasms
A neuroendocrine-specific protein localized to the endoplasmic reticulum by distal degradation.
Pituitary Neoplasms
Carbohydrate processing of thyrotropin differs from that of free alpha-subunit and total glycoproteins in microsomal subfractions of mouse pituitary tumor.
Pituitary Neoplasms
Thyroid-stimulating hormone subunit processing and combination in microsomal subfractions of mouse pituitary tumor.
Plasmacytoma
Analogues of hexamethylmelamine. The anti-neoplastic activity of derivatives with enhanced water solubility.
Plasmacytoma
Correlation of the effect of feeding upon the cell cycle distribution profiles of MPC-11 cells with the relative appearance of [3H]-choline labeled material in microsomal subfractions and other cell fractions.
Plasmacytoma
DNA polymerases from intracisternal A-type particles on the mouse plasmacytoma MPC 11.
Plasmacytoma
Effect of a zinc-deficient diet on mitochondrial and microsomal lipid composition in TEPC-183 plasmacytoma.
Plasmacytoma
Microsomal cAMP-independent histone H1 kinase activity in plasmacytoma, Morris hepatoma and normal liver.
Plasmacytoma
Purification and characterization of a specific histone H1 protein kinase from mouse plasmacytoma.
Plasmacytoma
Resolution and general properties of different types of ribosomal protein kinases in mouse plasmocytoma.
Plasmacytoma
The isolation of microsomal subfractions of mouse plasmacytoma cells: the effect of salt concentration during nitrogen cavitation.
Plasmacytoma
Ultrastructure and polysome content of the microsomal subfractions of mouse plasmacytoma cells.
Pleural Effusion
Potentiation of oxygen-induced lung injury in rats by the mechanism-based cytochrome P-450 inhibitor, 1-aminobenzotriazole.
Pneumatosis Cystoides Intestinalis
Unusual occupational gastrointestinal and hepatic disorders.
Pneumococcal Infections
Effects of pneumococcal infection on rat liver microsomal enzymes and lipogenesis by isolated hepatocytes.
Pneumoconiosis
[Gene variance in microsomal epoxide hydrolase and the susceptibility of coal workers' pneumoconiosis].
Pneumonia
Cigarette smoke induces cyclooxygenase-2 and microsomal prostaglandin E2 synthase in human lung fibroblasts: implications for lung inflammation and cancer.
Pneumonia
Genetic polymorphisms in the cytochromes P-450 (1A1, 2E1), microsomal epoxide hydrolase and glutathione S-transferase M1, T1, and P1 genes, and their relationship with chronic bronchitis and relapsing pneumonia in children.
Pneumonia
[Changes in the content and activity of liver and lung microsomal enzymes in experimental pneumonia and their possible correction]
Polycystic Kidney Diseases
Inhibition of catalase and epoxide hydrolase by the renal cystogen 2-amino-4,5-diphenylthiazole and its metabolites.
Polycystic Kidney, Autosomal Recessive
Inhibition of catalase and epoxide hydrolase by the renal cystogen 2-amino-4,5-diphenylthiazole and its metabolites.
Polycystic Ovary Syndrome
Quantitative Methylation Level of the EPHX1 Promoter in Peripheral Blood DNA Is Associated with Polycystic Ovary Syndrome.
Polycystic Ovary Syndrome
Two exonic single nucleotide polymorphisms in the microsomal epoxide hydrolase gene are associated with polycystic ovary syndrome.
Polyendocrinopathies, Autoimmune
Hepatic autoantigens in patients with autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy.
Polymyositis
Effects of immunosuppressive treatment on microsomal prostaglandin E synthase 1 and cyclooxygenases expression in muscle tissue of patients with polymyositis or dermatomyositis.
Polymyositis
[Non-organ specific anticytoplasmic autoantibodies. Immunoserologic detection and diagnostic relevance]
Porphyria Cutanea Tarda
Hepatic arachidonic acid metabolism is disrupted after hexachlorobenzene treatment.
Porphyria, Acute Intermittent
Melatonin reduces rat hepatic macromolecular damage due to oxidative stress caused by delta-aminolevulinic acid.
Porphyrias
2,3,7,8-Tetrachlorodibenzo-p-dioxin-induced porphyria in genetically inbred mice: partial antagonism and mechanistic studies.
Porphyrias
Changes in some intestinal enzyme activities in experimental hexachlorobenzene-induced porphyria and modifying effects of diet.
Porphyrias
Chemically induced porphyria: increased microsomal heme turnover after treatment with allylisopropylacetamide.
Porphyrias
Distinction between octachlorostyrene and hexachlorobenzene in their potentials to induce ethoxyphenoxazone deethylase and cause porphyria in rats and mice.
Porphyrias
Hepatic alteration of tryptophan metabolism in an acute porphyria model Its relation with gluconeogenic blockage.
Porphyrias
Hepatic arachidonic acid metabolism is disrupted after hexachlorobenzene treatment.
Porphyrias
Hexachlorobenzene as a persistent organic pollutant: Toxicity and molecular mechanism of action.
Porphyrias
Hexachlorobenzene-induced porphyria in Japanese quail: changes in microsomal enzymes.
Porphyrias
Melatonin reduces rat hepatic macromolecular damage due to oxidative stress caused by delta-aminolevulinic acid.
Porphyrias
Microsomal enzyme induction and clinical aggravation of porphyria: the evaluation of human urinary 6beta-hydroxycortisol/cortisol ratio as the index of hepatic CYP3A4 activity.
Porphyrias
Modulation by iron of hepatic microsomal and nuclear cytochrome P450, and cytosolic glutathione S-transferase and peroxidase in C57BL/10ScSn mice induced with polychlorinated biphenyls (Aroclor 1254).
Porphyrias
Porphyrin biosynthesis. Enhancement of the fractional catabolic rate of microsomal haem in chemically induced porphyria.
Porphyrias
Relationship of basic research in toxicology to environmental standard setting: the case of polybrominated biphenyls in Michigan.
Porphyrias
[Behaviour of the hepatic glutathione (GSH) in the rat in continuous administration of hexachlorobenzene (HCB) (author's transl)]
Porphyrias
[Effect of thyroid hormones on the modulation of genetic expression of liver cytosolic malic enzyme, in rats poisoned with hexachlorobenzene]
Porphyrias
[Induction of mixed microsomal oxidase in experimental hexachlorobenzene porphyria in rabbits]
Porphyrias
[Porphyria symptoms and microsomal enzyme activity in rat liver following administration of hexachlorobenzene]
Postpartum Thyroiditis
Association between thyroid microsomal antibodies of subclass IgG-1 and hypothyroidism in autoimmune postpartum thyroiditis.
Postpartum Thyroiditis
IgG subclass distribution and relative functional affinity of thyroid microsomal antibodies in postpartum thyroiditis.
Postpartum Thyroiditis
Thyroid function and autoimmune manifestations in insulin-dependent diabetes mellitus during and after pregnancy.
Postpartum Thyroiditis
[Post-partum autoimmune thyroiditis in a patient presenting with Sheehan's syndrome]
Pre-Eclampsia
A polymorphism in the gene for microsomal epoxide hydrolase is associated with pre-eclampsia.
Pre-Eclampsia
Association of microsomal epoxide hydrolase gene polymorphism and pre-eclampsia in Turkish women.
Pre-Eclampsia
Comparison of ex vivo inhibitory effect between 2-hydroxyestradiol and its 17-sulfate on rat hepatic microsomal lipid peroxidation.
Pre-Eclampsia
Complement fixing antibody against solubilized placental microsomal fraction in pre-eclampsia sera.
Pre-Eclampsia
Dimethyl acetals, an indirect marker of the endogenous antioxidant plasmalogen level, are reduced in blood lipids of Sudanese pre-eclamptic subjects whose background diet is high in carbohydrate.
Pre-Eclampsia
eNOSI4 and EPHX1 polymorphisms affect maternal susceptibility to preeclampsia: analysis of five polymorphisms predisposing to cardiovascular disease in 279 Caucasian and 241 African women.
Pre-Eclampsia
Oxidative stress-related genes (EPHX1 and MnSOD) polymorphism and risk of pre-eclampsia: a meta-analysis.
Pre-Eclampsia
PP057. ENOSI4 and EPHX1 polymorphisms affect maternal susceptibility topreeclampsia - Analysis of five polymorphisms predisposing tocardiovascular disease in 279 caucasian and 241 african women.
Pre-Eclampsia
Two exonic single nucleotide polymorphisms in the microsomal epoxide hydrolase gene are jointly associated with preeclampsia.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Altered expression of nuclear non-histone protein (p44/46) in different stages of B-chronic lymphocytic leukemia.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Association between polymorphisms of EPHX1 and XRCC1 genes and the risk of childhood acute lymphoblastic leukemia.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Role of the CYP2D6, EPHX1, MPO, and NQO1 genes in the susceptibility to acute lymphoblastic leukemia in Brazilian children.
Primary Ovarian Insufficiency
Circulating auto-antibodies against the zona pellucida and thyroid microsomal antigen in women with premature ovarian failure.
prostaglandin-e synthase deficiency
The impact of microsomal prostaglandin e synthase 1 on blood pressure is determined by genetic background.
Prostatic Hyperplasia
Acid phosphatase in the lysosomal and microsomal fractions of human prostatic epithelium.
Prostatic Hyperplasia
Estradiol/androgen receptors during aging: microsomal distribution in human benign prostatic hypertrophy.
Prostatic Hyperplasia
Low-affinity nerve growth factor receptors (p75LNGFR) in human prostate tissue: stromal localisation.
Prostatic Hyperplasia
Prostatic cancer/benign prostatic hypertrophy. Subcellular distribution of estradiol/androgen receptors.
Prostatic Hyperplasia
Reduced expression of the low affinity nerve growth factor receptor in benign and malignant human prostate tissue and loss of expression in four human metastatic prostate tumor cell lines.
Prostatic Neoplasms
Androgen-sensitive microsomal signaling networks coupled to the proliferation and differentiation of human prostate cancer cells.
Prostatic Neoplasms
Associations between smoking, polymorphisms in polycyclic aromatic hydrocarbon (PAH) metabolism and conjugation genes and PAH-DNA adducts in prostate tumors differ by race.
Prostatic Neoplasms
Cytochrome P4501A1 and microsomal epoxide hydrolase gene polymorphisms: gene-environment interaction and risk of prostate cancer.
Prostatic Neoplasms
Inhibition of aromatase (P450Arom) by some 1-(benzofuran-2-ylmethyl)imidazoles.
Prostatic Neoplasms
Inhibition of CHOP accentuates the apoptotic effect of ?-mangostin from the mangosteen fruit (Garcinia mangostana) in 22Rv1 prostate cancer cells.
Prostatic Neoplasms
Inhibition of steroid 5 alpha-reductase by specific aliphatic unsaturated fatty acids.
Prostatic Neoplasms
Inhibitors of human and rat testes microsomal 17beta-hydroxysteroid dehydrogenase (17beta-HSD) as potential agents for prostatic cancer.
Prostatic Neoplasms
Linking microsomal prostaglandin E Synthase-1/PGE-2 pathway with miR-15a and -186 expression: Novel mechanism of VEGF modulation in prostate cancer.
Prostatic Neoplasms
Microsomal epoxide hydrolase gene polymorphisms and susceptibility to prostate cancer: A systematic review.
Prostatic Neoplasms
Microsomal epoxide hydrolase polymorphisms, cigarette smoking and prostate cancer risk in the Slovak population.
Prostatic Neoplasms
Pharmacokinetics-pharmacodynamics and antitumor activity of mercaptoacetamide-based histone deacetylase inhibitors.
Prostatic Neoplasms
Polymorphisms in polycyclic aromatic hydrocarbon metabolism and conjugation genes, interactions with smoking and prostate cancer risk.
Prostatic Neoplasms
Prolactin binding components in prostatic cancer tissue specimens obtained by TURP.
Prostatic Neoplasms
Prostatic cancer/benign prostatic hypertrophy. Subcellular distribution of estradiol/androgen receptors.
Prostatic Neoplasms
Quantitative cancer proteomics: stable isotope labeling with amino acids in cell culture (SILAC) as a tool for prostate cancer research.
Prostatic Neoplasms
Theaflavin-3,3'-digallate and penta-O-galloyl-beta-D-glucose inhibit rat liver microsomal 5alpha-reductase activity and the expression of androgen receptor in LNCaP prostate cancer cells.
Prostatic Neoplasms
Xenobiotic-metabolizing gene variants, pesticide use, and the risk of prostate cancer.
Protein Deficiency
A distal effect of microsomal triglyceride transfer protein deficiency on the lysosomal recycling of CD1d.
Protein Deficiency
Effect of cross-fostering rats at birth on the normal supply of essential fatty acids during protein deficiency.
Protein Deficiency
Effect of protein deficiency on the hepatic microsomal mixed function oxidase. III-Influence on aflatoxin B1 metabolism and epoxide hydrase activity.
Protein Deficiency
Effect of protein deficiency on the inducibility of the hepatic microsomal drug-metabolizing enzyme system. 3.
Protein Deficiency
Effect of protein deficiency on the inducibility of the hepatic microsomal drug-metabolizing enzyme system. I. Effect on substrate interaction with cytochrome P-450.
Protein Deficiency
Effect of protein deficiency on the inducibility of the hepatic microsomal drug-metabolizng enzyme system. II. Effect of enzyme kinetics and electron transport system.
Protein Deficiency
Effects of protein deficiency on uridine diphosphate glucuronyltransferase activity and phospholipid composition of rat liver microsomal fraction.
Protein Deficiency
Influence of protein deficiency on the inhibition of hepatic microsomal detoxication by methyl mercury in two rat strains.
Protein Deficiency
Myocardial effects and pharmacokinetics of digoxin and ouabain in protein-deficient guinea pigs.
Protein Deficiency
Protein deficiency in pregnant rats causes decreased levels of plasma somatomedin and its carrier protein associated with reduced plasma levels of placental lactogen and hepatic lactogenic receptor number.
Protein Deficiency
The combined effects of protein deficiency and chronic ethanol administration on rat ethanol metabolism.
Protein Deficiency
The effect of protein deficiency and microsomal enzyme induction by DDT and phenobarbitone on the acute toxicity of chloroform and a pyrrolizidine alkaloid, retrorsine.
Protein Deficiency
The phospholipid-dependence of uridine diphosphate glucuronyltransferase. Effect of protein deficiency on the phospholipid composition and enzyme activity of rat liver microsomal fraction.
Protein-Energy Malnutrition
Nutrition-related alterations in liver microsomal testosterone hydroxylases.
Protein-Energy Malnutrition
Pharmacokinetic changes in drugs during protein-calorie malnutrition: correlation between drug metabolism and hepatic microsomal cytochrome P450 isozymes.
Protein-Energy Malnutrition
Prevention of c-Jun/activator protein-1 activation and microsomal epoxide hydrolase induction in the rat liver by cysteine during protein-calorie malnutrition.
Proteinuria
Relationship between microtubules and Golgi apparatus in hepatocytes: a quantitative study during experimental nephrosis.
Psoriasis
Aryl hydrocarbon hydroxylase, epoxide hydrolase, and benzo[a]-pyrene metabolism in human epidermis: comparative studies in normal subjects and patients with psoriasis.
Psoriasis
Cyclosporine A metabolism by cytochrome P-450III occurs in microsomes from rat liver but not from normal epidermis or psoriatic lesions.
Psoriasis
Decreased epidermal aryl hydrocarbon hydroxylase and localized pustular psoriasis.
Psoriasis
Effects of antipsoriatic therapies on hepatic microsomal enzyme activity in patients with psoriasis.
Psoriasis
Systematic evaluation of association between the microsomal glutathione S-transferase 2 common variation and psoriasis vulgaris in Chinese population.
Psoriasis
The effects of retinoids and terbinafine on the human hepatic microsomal metabolism of cyclosporin.
Pulmonary Adenomatosis, Ovine
Aetiology of jaagsiekte: transmission by means of subcellular fractions and evidence for the involvement of a retrovirus.
Pulmonary Disease, Chronic Obstructive
A bioinformatics strategy for detecting the complexity of Chronic Obstructive Pulmonary Disease in Northern Chinese Han Population.
Pulmonary Disease, Chronic Obstructive
Analyses of association between PPAR gamma and EPHX1 polymorphisms and susceptibility to COPD in a Hungarian cohort, a case-control study.
Pulmonary Disease, Chronic Obstructive
Association between polymorphism in gene for microsomal epoxide hydrolase and susceptibility to emphysema.
Pulmonary Disease, Chronic Obstructive
Association between polymorphisms of microsomal epoxide hydrolase and COPD: results from meta-analyses.
Pulmonary Disease, Chronic Obstructive
Association of Functional Variants of Phase I and II Genes with Chronic Obstructive Pulmonary Disease in a Serbian Population.
Pulmonary Disease, Chronic Obstructive
Combined analysis of EPHX1, GSTP1, GSTM1 and GSTT1 gene polymorphisms in relation to chronic obstructive pulmonary disease risk and lung function impairment.
Pulmonary Disease, Chronic Obstructive
Correlation of EPHX1, GSTP1, GSTM1, and GSTT1 genetic polymorphisms with antioxidative stress markers in chronic obstructive pulmonary disease.
Pulmonary Disease, Chronic Obstructive
Decreased expression of antioxidant enzymes and increased expression of chemokines in COPD lung.
Pulmonary Disease, Chronic Obstructive
Detection of polymorphisms at exons 3 (Tyr113-->His) and 4 (His139-->Arg) of the microsomal epoxide hydrolase gene using fluorescence PCR method combined with melting curves analysis.
Pulmonary Disease, Chronic Obstructive
Effect of N-acetylcysteine in COPD patients with different microsomal epoxide hydrolase genotypes.
Pulmonary Disease, Chronic Obstructive
EPHX1 polymorphisms, COPD and asthma in 47,000 individuals and in meta-analysis.
Pulmonary Disease, Chronic Obstructive
EPHX1 Y113H polymorphism is associated with increased risk of chronic obstructive pulmonary disease in Kazakhstan population.
Pulmonary Disease, Chronic Obstructive
Exploration of association between EPHX1 and chronic obstructive pulmonary disease on the basis of combined data mining.
Pulmonary Disease, Chronic Obstructive
Exploring the interaction among EPHX1, GSTP1, SERPINE2, and TGFB1 contributing to the quantitative traits of chronic obstructive pulmonary disease in Chinese Han population.
Pulmonary Disease, Chronic Obstructive
Genes, oxidative stress, and the risk of chronic obstructive pulmonary disease.
Pulmonary Disease, Chronic Obstructive
Genetic association analysis of COPD candidate genes with bronchodilator responsiveness.
Pulmonary Disease, Chronic Obstructive
Genetic association between COPD and polymorphisms in TNF, ADRB2 and EPHX1.
Pulmonary Disease, Chronic Obstructive
Genetic associations with hypoxemia and pulmonary arterial pressure in COPD.
Pulmonary Disease, Chronic Obstructive
Genetic determinants of emphysema distribution in the national emphysema treatment trial.
Pulmonary Disease, Chronic Obstructive
Genetic polymorphism of epoxide hydrolase and glutathione S-transferase in COPD.
Pulmonary Disease, Chronic Obstructive
Genetic polymorphisms in chronic obstructive pulmonary disease.
Pulmonary Disease, Chronic Obstructive
Genetic polymorphisms of GSTP1 and mEPHX correlate with oxidative stress markers and lung function in COPD.
Pulmonary Disease, Chronic Obstructive
Genetic susceptibility to chronic obstructive pulmonary disease in Koreans: combined analysis of polymorphic genotypes for microsomal epoxide hydrolase and glutathione S-transferase M1 and T1.
Pulmonary Disease, Chronic Obstructive
Genetic variants of microsomal epoxide hydrolase and glutamate-cysteine ligase in COPD.
Pulmonary Disease, Chronic Obstructive
Genetic variations in detoxification enzymes and HIF-1? in Japanese patients with COPD.
Pulmonary Disease, Chronic Obstructive
Glutathione S-transferase and microsomal epoxide hydrolase gene polymorphisms and risk of chronic obstructive pulmonary disease in Slovak population.
Pulmonary Disease, Chronic Obstructive
IL10 polymorphisms are associated with airflow obstruction in severe alpha1-antitrypsin deficiency.
Pulmonary Disease, Chronic Obstructive
Lack of association between glutathione S-transferase P1 polymorphism and COPD in Koreans.
Pulmonary Disease, Chronic Obstructive
Microsomal epoxide hydrolase gene polymorphisms and risk of chronic obstructive pulmonary disease: A comprehensive meta-analysis.
Pulmonary Disease, Chronic Obstructive
Microsomal Epoxide Hydrolase Gene Polymorphisms and Susceptibility to Chronic Obstructive Pulmonary Disease in Tunisian Population.
Pulmonary Disease, Chronic Obstructive
Microsomal epoxide hydrolase genotypes and chronic obstructive pulmonary disease in Japanese.
Pulmonary Disease, Chronic Obstructive
Microsomal epoxide hydrolase is not associated with COPD in a community-based sample.
Pulmonary Disease, Chronic Obstructive
Oxidative Stress and Genetic Variants of Xenobiotic-Metabolising Enzymes Associated with COPD Development and Severity in Serbian Adults.
Pulmonary Disease, Chronic Obstructive
Polymorphic variation in surfactant protein B is associated with COPD exacerbations.
Pulmonary Disease, Chronic Obstructive
Polymorphism of microsomal epoxide hydrolase is associated with chronic obstructive pulmonary disease and bronchodilator response.
Pulmonary Disease, Chronic Obstructive
Polymorphisms for microsomal epoxide hydrolase and genetic susceptibility to COPD.
Pulmonary Disease, Chronic Obstructive
Polymorphisms of N-acetyltransferases, glutathione S-transferases, microsomal epoxide hydrolase and sulfotransferases: influence on cancer susceptibility.
Pulmonary Disease, Chronic Obstructive
Relationship between COPD and polymorphisms of HOX-1 and mEPH in a Chinese population.
Pulmonary Disease, Chronic Obstructive
Relationship between polymorphisms of genes encoding microsomal epoxide hydrolase and glutathione S-transferase P1 and chronic obstructive pulmonary disease.
Pulmonary Disease, Chronic Obstructive
Special issue on carbon monoxide and exhaled biomarkers in human disease.
Pulmonary Disease, Chronic Obstructive
Susceptibility genes for rapid decline of lung function in the lung health study.
Pulmonary Disease, Chronic Obstructive
Update in chronic obstructive pulmonary disease: role of antioxidant and metabolizing gene polymorphisms.
Pulmonary Disease, Chronic Obstructive
[Association between polymorphisms in the microsomal epoxide hydrolase (mEH) gene and chronic obstructive pulmonary disease]
Pulmonary Disease, Chronic Obstructive
[Genetic features during chronic obstructive pulmonary disease]
Pulmonary Disease, Chronic Obstructive
[Genetic risk factors for chronic obstructive pulmonary disease (COPD)]
Pulmonary Disease, Chronic Obstructive
[Genetics risk factors in chronic obstructive pulmonary disease]
Pulmonary Disease, Chronic Obstructive
[Microsomal epoxide hydrolase gene polymorphism and susceptibility to chronic obstructive pulmonary disease in Han nationality of North China]
Pulmonary Disease, Chronic Obstructive
[Role of genetic factors in the development of COPD]
Pulmonary Disease, Chronic Obstructive
[Role of polymorphic variants of cytochrome P450 genes (CYP1A1, CYP2E1) and microsomal epoxide hydrolase (mEPHX) in pathogenesis of cystic fibrosis and chronic respiratory tract diseases]
Pulmonary Disease, Chronic Obstructive
[Study on the relationship between EPHX1 gene polymorphism and antioxidant capacity in patients with chronic obstructive pulmonary disease].
Pulmonary Fibrosis
Effect of bleomycin-induced fibrosis on pulmonary metabolism of selected xenobiotics.
Purpura, Thrombocytopenic, Idiopathic
Human spleen heme oxygenase and microsomal electron transport system component activity in normals and in patients with hemolytic anemia, idiopathic thrombocytopenic purpura, and lymphoproliferative disorders.
Pyelonephritis
[Disorders of the processes of protein biosynthesis and a decrease in the content of cytochromes P-450 and b5 in the microsomal fraction of rat kidney in the dynamics of development of acute pyelonephritis]
Pyelonephritis
[Lipid peroxidation and Ca-dependent ATPase activity in the microsomal fraction of renal tissue in patients with nephrolithiasis and chronic pyelonephritis]
Renal Insufficiency
Effects of acute renal failure induced by uranyl nitrate on the pharmacokinetics of intravenous theophylline in rats: the role of CYP2E1 induction in 1,3-dimethyluric acid formation.
Renal Insufficiency
Hepatic microsomal oxidative N-demethylation in rats with renal failure [proceedings]
Renal Insufficiency
Involvement of endogenous prostaglandin E2 in tubular epithelial regeneration through inhibition of apoptosis and epithelial-mesenchymal transition in cisplatin-induced rat renal lesions.
Renal Insufficiency
Salivary antipyrine kinetics in hepatic and renal disease and in patients on anticonvulsant therapy.
Reperfusion Injury
Cytochrome P450 and myocardial ischemia: potential pharmacological implication for cardioprotection.
Reperfusion Injury
Effects of normothermic hepatic ischemia-reperfusion injury on the in vivo, isolated perfused liver, and microsomal disposition of chlorzoxazone, a cytochrome P450 2E1 probe, in rats.
Reperfusion Injury
Hydrogen sulfide modulates sub-cellular susceptibility to oxidative stress induced by myocardial ischemic reperfusion injury.
Respiratory Tract Diseases
[Role of polymorphic variants of cytochrome P450 genes (CYP1A1, CYP2E1) and microsomal epoxide hydrolase (mEPHX) in pathogenesis of cystic fibrosis and chronic respiratory tract diseases]
Reye Syndrome
Effect of acetylsalicylic acid on fatty acid omega-hydroxylation in rat liver.
Reye Syndrome
Reye's syndrome: preservation of mitochondrial enzymes in brain and muscle compared with liver.
Rhabdomyolysis
Rhabdomyolysis in a patient taking simvastatin after addition of cyclosporine therapy.
Rheumatic Diseases
Immunoblotting as a confirmatory test for antimitochondrial antibodies in primary biliary cirrhosis.
Riboflavin Deficiency
Effect of riboflavin deficiency on liver microsomal enzyme system and lipid peroxidation in male rats.
Riboflavin Deficiency
Effect of riboflavin deficiency on phenobarbital and 3-methylcholanthrene induction of microsomal drug-metabolizing enzymes of the rat.
Riboflavin Deficiency
Lipid metabolism in riboflavin-deficient rats. 2. Mitochondrial fatty acid oxidation and the microsomal desaturation pathway.
Riboflavin Deficiency
Possible role of riboflavin deficiency in epithelial neoplasia. 3. Induction of microsomal aryl hydrocarbon hydroxylase.
Riboflavin Deficiency
[Effect of thiamine and riboflavin derivatives on the activity of xenobiotic-metabolizing enzyme and on the pharmacologic effect of analgesics]
Rickets
Mutation of the CYP2R1 Vitamin D 25-Hydroxylase in a Saudi Arabian Family with Severe Vitamin D Deficiency.
Sarcoma
Biosynthesis of plasmalogens by the microsomal fraction of fischer R-3259 sarcoma. Influence of specific 2-acyl chains on the desaturation of 1-alkyl-2-acyl-sn-glycero-3-phosphoethanolamine.
Sarcoma
[Differing microsomal monoxygenase activity in the cells of ascitic and solid forms of transplantable tumors]
Sarcoma 180
Effects of the antitumor agents from various natural sources on drug-metabolizing system, phagocytic activity and complement system in sarcoma 180-bearing mice.
Sarcoma 180
The influence of Propionibacterium acnes (Corynebacterium parvum) fractions on immune response in vivo.
Sarcoma, Avian
NUCLEOTIDE SEQUENCE INVESTIGATIONS IN MICROSOMAL RIBONUCLEIC ACIDS OF NORMAL AND ROUS SARCOMA VIRUS-INFECTED TISSUES.
Sarcoma, Avian
[Virus-specific double-stranded RNA in the composition of the microsomal RNA of Rous sarcoma cells]
Schistosomiasis
Activity of liver microsomal enzymes during the chronic phase of murine schistosomiasis.
Schistosomiasis
Alterations of hepatic microsomal enzymes in the early phase of murine schistosomiasis.
Schistosomiasis
Effect of murine schistosomiasis on hepatic cytochrome P-450 and microsomal protein.
Schistosomiasis
Hepatic cytochrome P-450 system in experimental hepatosplenic schistosomiasis. Presence of an artifact in spectrophotometric analysis.
Schistosomiasis
The pharmacokinetics of antipyrine in patients with graded severity of schistosomiasis.
Schistosomiasis mansoni
Different levels of Schistosoma mansoni infection increased the mutagenicity of benzo(a)pyrene, the activity of aryl hydrocarbon hydroxylase and the formation of hepatic microsomal hydrogen peroxide.
Schistosomiasis mansoni
Hepatic cytochrome P-450 system in experimental hepatosplenic schistosomiasis. Presence of an artifact in spectrophotometric analysis.
Scleroderma, Diffuse
Autoantibody to gp50, a glycoprotein shared in common between fibroblasts and lymphocytes, in progressive systemic sclerosis.
Scrapie
Attempts to convert the cellular prion protein into the scrapie isoform in cell-free systems.
Scrapie
Mouse-adapted scrapie infection of SN56 cells: greater efficiency with microsome-associated versus purified PrP-res.
Scrapie
Prion-removal capacity of chromatographic and ethanol precipitation steps used in the production of albumin and immunoglobulins.
Scurvy
The absence of an inhibitory effect of metyrapone (2-methyl-1,2-di (3-pyridyl) propan-1-one) on hepatic microsomal hydroxylation in scurvy.
Seizures
Antiepileptic drugs and hormonal contraceptives in adolescent women with epilepsy.
Seizures
Correlation between effects of acute acetazolamide administration to mice on electroshock seizure threshold and maximal electroshock seizure pattern, and on carbonic anhydrase activity in subcellular fractions of brain.
Seizures
Different EPHX1 methylation levels in promoter area between carbamazepine-resistant epilepsy group and carbamazepine-sensitive epilepsy group in Chinese population.
Seizures
Effects of SKF525A, phenobarbital, fasting, and carnitine on the anticonvulsant activity and neurotoxicity of valproate in mice.
Seizures
Evidence for increased activity of mouse brain fatty acid cyclooxygenase following drug-induced convulsions.
Seizures
Modulation of the intracellular and H3-histamine receptors and chemically-induced seizures in mice.
Seizures
Picrotoxin-induced convulsions alters rat brain microsomal membrane structural properties.
Seizures
Selenium and topiramate modulates brain microsomal oxidative stress values, Ca2+-ATPase activity, and EEG records in pentylentetrazol-induced seizures in rats.
Seizures
Synthesis of arachidonoyl coenzyme A and docosahexaenoyl coenzyme A in synaptic plasma membranes of cerebrum and microsomes of cerebrum, cerebellum, and brain stem of rat brain.
Seizures
Topiramate and vitamin e modulate the electroencephalographic records, brain microsomal and blood antioxidant redox system in pentylentetrazol-induced seizure of rats.
Seizures
[Evaluation of monitoring the efficacy of phenobarbital as an anticonvulsant agents using the fluorescence-polarization immunoassay]
Seizures
[Liver extract effect on liver microsomal system and on an experimental model of intoxication]
Seizures
[Na, K-ATP-ase and acetylcholinesterase activity of the membrane structures of the rat brain and spinal cord during the seizure process]
Seminoma
Glutathione S-transferase expression in the human testis and testicular germ cell neoplasia.
Sepsis
Calcium content in liver and heart and its intracellular distribution in liver during endotoxicosis and sepsis in rats.
Sepsis
Changes in inositol 1,4,5-triphosphate binding in microsomal fractions from the rat liver during sepsis.
Sepsis
Changes of adenosine triphosphate-dependent calcium uptake in microsomal fractions of rat liver during sepsis.
Sepsis
Effect of endotoxicosis and sepsis on intracellular calcium homeostasis in rat liver. Mitochondrial and microsomal calcium uptake.
Sepsis
In vivo regulation of acyl-CoA synthetase mRNA and activity by endotoxin and cytokines.
Sepsis
Intestine-specific Mttp deletion decreases mortality and prevents sepsis-induced intestinal injury in a murine model of Pseudomonas aeruginosa pneumonia.
Sepsis
Suppression of hepatic cytochrome p450-mediated drug metabolism during the late stage of sepsis in rats.
Sepsis
The effect of sepsis during parenteral nutrition on hepatic microsomal function in rats.
Sepsis
Urinary excretion of 3-methylhistidine: an assessment of muscle protein catabolism in adult normal subjects and during malnutrition, sepsis, and skeletal trauma.
Sepsis
Vitamins C and E protect hepatic cytochrome P450 dysfunction induced by polymicrobial sepsis.
Severe Combined Immunodeficiency
Synthesis and profiling of benzylmorpholine 1,2,4,5-tetraoxane analogue N205: Towards tetraoxane scaffolds with potential for single dose cure of malaria.
Sialadenitis
[The sources of active forms of oxygen in the normal oral tissues and in pathology]
Silicosis
Alterations in the pulmonary microsomal cytochrome P-450 system after exposure of rats to silica.
Silicosis
Pulmonary microsomal metabolism of benzo[a]pyrene following exposure of rats to silica.
Silicosis
[Biochemical investigations of the silicosis problem; enzyme inhibition by silicic acid in the case of microsomal glucose-6-phosphatase.]
Sjogren-Larsson Syndrome
Characterization of the human omega-oxidation pathway for omega-hydroxy-very-long-chain fatty acids.
Sjogren-Larsson Syndrome
Clinical, biochemical and molecular genetic characteristics of 19 patients with the Sjögren-Larsson syndrome.
Sjogren-Larsson Syndrome
Defective metabolism of leukotriene B4 in the Sjögren-Larsson syndrome.
Sjogren-Larsson Syndrome
Enzymatic diagnosis of Sjögren-Larsson syndrome using electrospray ionization mass spectrometry.
Sjogren-Larsson Syndrome
Microsomal fatty aldehyde dehydrogenase catalyzes the oxidation of aliphatic aldehyde derived from ether glycerolipid catabolism: implications for Sjögren-Larsson syndrome.
Sjogren-Larsson Syndrome
Monitoring of fatty aldehyde dehydrogenase by formation of pyrenedecanoic acid from pyrenedecanal.
Sjogren-Larsson Syndrome
MRI and 1H-MRS findings of three patients with Sjögren-Larsson syndrome.
Sjogren-Larsson Syndrome
Novel and recurrent ALDH3A2 mutations in Italian patients with Sjögren-Larsson syndrome.
Sjogren-Larsson Syndrome
Phenotypic variability among adult siblings with Sjögren-Larsson syndrome.
Skin Diseases
[Effect of microsomal monooxygenase inductor zixoryn on clinico-immunologic indicators in allergologic patients]
Skin Diseases
[Role of polymorphous genes of xenobiotic biotransformation system in pathogenesis of occupational allergic dermatoses].
Skin Neoplasms
Association of Environmental Arsenic Exposure, Genetic Polymorphisms of Susceptible Genes, and Skin Cancers in Taiwan.
Small Cell Lung Carcinoma
Combined analysis of polymorphisms in glutathione S-transferase M1 and microsomal epoxide hydrolase in lung cancer patients.
Small Cell Lung Carcinoma
[Assessment of the functional state of microsomal enzymes in the liver in patients with small cell lung cancer treated with cytostatic drugs]
Small Cell Lung Carcinoma
[The interaction between microsomal epoxide hydrolase polymorphisms and indoor pollution in non small cell lung cancer]
Spinal Cord Injuries
Motor enrichment sustains hindlimb movement recovered after spinal cord injury and glial transplantation.
Spinal Cord Injuries
Neuroprotective Effects of Hypothermia Following Spinal Cord Injury in Rats: Comparative Study Between Epidural Hypothermia and Systemic Hypothermia.
Spondylitis, Ankylosing
Antithyroid-antibody activity in the snyovial fluid of patients with various arthritides.
Spondylitis, Ankylosing
Leukocyte migration test in Crohn's disease, ulcerative colitis, and ankylosing spondylitis using Crohn's colon homogenate, mitochondrial, and microsomal fractions.
Squamous Cell Carcinoma of Head and Neck
Case-control study of oral and oropharyngeal cancer in whites and genetic variation in eight metabolic enzymes.
Squamous Cell Carcinoma of Head and Neck
Expression of cyclooxygenase-2 and microsomal prostagalandin E synthase-1 in head and neck squamous cell carcinoma.
Squamous Cell Carcinoma of Head and Neck
Interaction between head and neck squamous cell carcinoma cells and fibroblasts in the biosynthesis of PGE2.
Starvation
A study of the glycerol phosphate acyltransferase and dihydroxyacetone phosphate acyltransferase activities in rat liver mitochondrial and microsomal fractions. Relative distribution in parenchymal and non-parenchymal cells, effects of N-ethylmaleimide, palmitoyl-coenzyme A concentration, starvation, adrenalectomy and anti-insulin serum treatment.
Starvation
Accumulation of phenols and catechols in isolated mouse hepatocytes in starvation or after pretreatment with acetone.
Starvation
Acute renal failure due to acetaminophen ingestion: a case report and review of the literature.
Starvation
Adipose-tissue Mg2+-dependent phosphatidate phosphohydrolase. Control of activity and subcellular distribution in vitro and in vivo.
Starvation
Characteristics of peroxisome proliferation: co-induction of peroxisomal fatty acid oxidation-related enzymes with microsomal laurate hydroxylase.
Starvation
Cytochrome P-450 and free radical generation in rat liver microsomes under the influence of prostaglandin E1.
Starvation
Effect of dehydration, starvation and sodium deprivation on microsomal ATPase in the kidney.
Starvation
Effect of diabetes, starvation, ethanol and isoniazid on rat liver microsomal 12 alpha-hydroxylase activity involved in bile acid biosynthesis.
Starvation
Effect of ethanol on the microsomal glutathione S-transferase activity in glutathione-depleted rat liver.
Starvation
Effect of prostaglandin F2 alpha on free radical generation, glutathione content and microsomal oxidase activities in rat liver microsomes induced either by ethanol or acetone.
Starvation
Effect of short term starvation on disposition kinetics of chloramphenicol in goats.
Starvation
Effects of starvation on liver microsomal P450 activity in juvenile Pleuronectes americanus.
Starvation
Effects of starvation on microsomal cytochrome P-450 and laurate-omega-hydroxylation of rat kidney and liver.
Starvation
Influence of starvation and hepatic microsomal enzyme induction on the mobilization of DDT residues in rats.
Starvation
Insulin regulates enzyme activity, malonyl-CoA sensitivity and mRNA abundance of hepatic carnitine palmitoyltransferase-I.
Starvation
Microsomal proteins and hemoproteins: enhancement of phenobarbital induction by prevention of breakdown due to starvation.
Starvation
Modulation of rat liver peroxisomal and microsomal fatty acid oxidation by starvation.
Starvation
Purification and characterization of 7 alpha-hydroxy-4-cholesten-3-one 12 alpha-hydroxylase.
Starvation
Starvation effect on rat kidney peroxisomal and microsomal fatty acid oxidation. A comparative study between liver and kidney.
Starvation
The activities of lipoprotein lipase and of enzymes involved in triacylglycerol synthesis in rat adipose tissue. Effects of starvation, dietary modification and of corticotropin injection.
Starvation
The effect of starvation on the kinetics of drug oxidation by hepatic microsomal enzymes from male and female rats.
Starvation
The effect of thioacetamide on rat liver plasma membrane enzymes and its potentiation by fasting.
Starvation
The regulation by gender, strain, dose, and feeding status of the induction of multiple forms of cytochrome P450 isozymes in rat hepatic microsomes by 2,4,5,2',4',5'-hexachlorobiphenyl.
Starvation
Xenobiotic biotransformation in the rainbow trout liver and kidney during starvation.
Starvation
[Activities of 3-hydroxyl-3-methylglutaryl-CoA reductase and acetyl-CoA carboxylase and the rate of mevalonic acid, squalene, sterol and fatty acid biosynthesis from [1-14C]acetyl-CoA and [2-14C]malonyl-CoA in rat liver: effects of Triton WR 1339, starvation and cholesterol diet]
Starvation
[The effect of starvation on mast cell functional activity and on the content of microsomal cytochromes in the liver]
Status Epilepticus
Inhibition of human microsomal PGE2 synthase-1 reduces seizure-induced increases of P-glycoprotein expression and activity at the blood-brain barrier.
Status Epilepticus
Pilocarpine-induced status epilepticus causes N-methyl-D-aspartate receptor-dependent inhibition of microsomal Mg(2+)/Ca(2+) ATPase-mediated Ca(2+) uptake.
Steatorrhea
Persistence of the intestinal defect in abetalipoproteinaemia after liver transplantation.
steroid 17alpha-monooxygenase deficiency
Isolated 17,20-Lyase Deficiency in a CYB5A Mutated Female With Normal Sexual Development and Fertility.
steroid 17alpha-monooxygenase deficiency
The genetic and functional basis of isolated 17,20-lyase deficiency.
steroid 21-monooxygenase deficiency
The common P450 oxidoreductase variant A503V is not a modifier gene for 21-hydroxylase deficiency.
steryl-sulfatase deficiency
Hydrolysis of deoxycorticosterone-21-yl sulphate and dehydroepiandrosterone sulphate by microsomal preparations of human placentae: evidence for a common enzyme.
steryl-sulfatase deficiency
Review: genetics of steroid sulphatase deficiency and X-linked ichthyosis.
Stevens-Johnson Syndrome
Association of ABCB1, CYP3A4, EPHX1, FAS, SCN1A, MICA, and BAG6 polymorphisms with the risk of carbamazepine-induced Stevens-Johnson syndrome/toxic epidermal necrolysis in Chinese Han patients with epilepsy.
Stomach Neoplasms
Association of microsomal epoxide hydrolase exon 3 Tyr113His and exon 4 His139Arg polymorphisms with gastric cancer in India.
Stomach Neoplasms
Blood group activities in water-soluble glycoproteins and in microsomal fractions of gastric mucosa in peptic ulcer and gastric cancer patients.
Stomach Neoplasms
Dietary aflatoxin B1 intake, genetic polymorphisms of CYP1A2, CYP2E1, EPHX1, GSTM1, and GSTT1, and gastric cancer risk in Korean.
Stomach Neoplasms
Expression of COX-2, mPGE-synthase1, MDR-1 (P-gp), and Bcl-xL: a molecular pathway of H pylori-related gastric carcinogenesis.
Stomach Neoplasms
Expression of microsomal prostaglandin E synthase-1 in intestinal type gastric adenocarcinoma and in gastric cancer cell lines.
Stomach Neoplasms
Expression of proteins related to prostaglandin E2 biosynthesis is increased in human gastric cancer and during gastric carcinogenesis.
Stomach Neoplasms
Polymorphisms in metabolic genes related to tobacco smoke and the risk of gastric cancer in the European prospective investigation into cancer and nutrition.
Stomach Ulcer
Effect of melatonin on secreted and induced matrix metalloproteinase-9 and -2 activity during prevention of indomethacin-induced gastric ulcer.
Stomach Ulcer
Role of microsomal prostaglandin E synthase-1 in the facilitation of angiogenesis and the healing of gastric ulcers.
Stomach Ulcer
[A method for stimulating the protective mechanisms of the gastric mucosa in peptic ulcer]
Stomatitis, Aphthous
Anemia and hematinic deficiencies in anti-gastric parietal cell antibody-positive and -negative recurrent aphthous stomatitis patients with anti-thyroid antibody positivity.
Stomatitis, Aphthous
Antigastric parietal cell and antithyroid autoantibodies in patients with recurrent aphthous stomatitis.
Stomatitis, Aphthous
Gastric parietal cell and thyroid autoantibodies in recurrent aphthous stomatitis patients with concomitant oral lichen planus.
Stomatitis, Aphthous
Serum thyroid autoantibodies are not associated with anemia, hematinic deficiencies, and hyperhomocysteinemia in patients with Behcet's disease.
Stroke
Variables in human liver microsome preparation: impact on the kinetics of l-alpha-acetylmethadol (LAAM) n-demethylation and dextromethorphan O-demethylation.
Stupor
Effects of a new fluorinated macrolide (P-0501A) and other erythromycins on drug metabolizing enzymes in rat liver.
Stupor
Hormonal environment and age influencing the activity of flumecinol, a synthetic enzyme inducer.
Stupor
Structure-activity relations for methylenedioxyphenyl and related compounds on hepatic microsomal enzyme function, as measured by prolongation of hexobarbital narcosis and zoxazolamine paralysis in mice.
Stupor
[Comparative studies of enzyme-inducing ability of phenobarbital, methylphenobarbital, glutethimide and their N-substituted morphoalkylic derivatives]
Superinfection
Isolation and characterization of an EBV superinfection-enhanced, host-cell-coded, 53,000-dalton protein.
Tachycardia
Tachycardia increases NADPH oxidase activity and RyR2 S-glutathionylation in ventricular muscle.
Testicular Neoplasms
Microsomal aromatase in testicular tumour tissue: increased activity in choriocarcinoma compared to embryonal carcinoma.
Tetanus
Probing the normal and autoimmune B cell repertoire with Epstein-Barr virus. Frequency of B cells producing monoreactive high affinity autoantibodies in patients with Hashimoto's disease and systemic lupus erythematosus.
Thiamine Deficiency
Hepatic drug metabolism and lipid peroxidation in thiamine deficient rats.
Thiamine Deficiency
[Transketolase activity and the TDP effect in tissues of animals with experimental tumors]
Thyroid Diseases
A high prevalence of human T-lymphotropic virus type I carriers in patients with antithyroid antibodies.
Thyroid Diseases
A simple semiquantitative radiometric measurement of antithyroglobulin antibodies in human serum. Comparison with hemagglutination method.
Thyroid Diseases
Absence of cross-reactivity to myeloperoxidase of anti-thyroid microsomal antibodies in patients with autoimmune thyroid diseases.
Thyroid Diseases
Anti-thyroid microsomal antibody in synovial fluid as a revealing feature of seronegative autoimmune thyroiditis.
Thyroid Diseases
Anti-thyroid peroxidase antibody in patients with autoimmune thyroid disease: possible identity with anti-microsomal antibody.
Thyroid Diseases
Antibodies against denatured and reduced thyroid microsomal antigen in autoimmune thyroid disease.
Thyroid Diseases
Autoimmune thyroid phenomena are not evidence for human lymphocyte antigen-genetic heterogeneity in insulin-dependent diabetes.
Thyroid Diseases
Binding of thyroid microsomes by lymphocytes from patients with thyroid disease and normal subjects.
Thyroid Diseases
CD4 cells from patients with autoimmune thyroid disease secrete interferon gamma after stimulation by thyroid microsomal antigen; CD8 cells suppress this secretion.
Thyroid Diseases
Chronic angio-oedema of the tongue associated with pernicious anaemia and Hashimoto's thyroiditis.
Thyroid Diseases
Clinical evaluation of a hemagglutination method for microsomal and thyroglobulin antibodies in autoimmune thyroid disease.
Thyroid Diseases
Comparison of measurements of in vitro production of antithyroid microsomal antibody versus antithyroid peroxidase antibody.
Thyroid Diseases
Comparison of serum thyroid microsomal and thyroid peroxidase autoantibodies in thyroid diseases.
Thyroid Diseases
Detection of autoantibodies to thyroid peroxidase in autoimmune thyroid diseases by micro-ELISA and immunoblotting.
Thyroid Diseases
Detection of microsomal and thyroglobulin antibodies in autoimmune thyroid diseases: evaluation of two methods.
Thyroid Diseases
Development of thyroid autoimmunity after administration of recombinant human interferon-alpha 2b for chronic viral hepatitis.
Thyroid Diseases
Differential autoantibody responses to thyroid peroxidase in patients with Graves' disease and Hashimoto's thyroiditis.
Thyroid Diseases
Discordant changes in serum anti-TSH receptor antibody and antithyroid microsomal antibody during pregnancy in autoimmune thyroid diseases.
Thyroid Diseases
Effect of HLA-DR positive thyrocytes on in vitro thyroid autoantibody production.
Thyroid Diseases
Effects of deglycosylation of human thyroperoxidase on its enzymatic activity and immunoreactivity.
Thyroid Diseases
Enzymatic deglycosylation of porcine thyroid peroxidase: effects on catalytic activity and immunoreactivity.
Thyroid Diseases
Identification of a thyroid microsomal antigen by Western blot and immunoprecipitation.
Thyroid Diseases
Improved ELISA for thyroid microsomal auto-antibodies. Comparison with haemagglutination and immunofluorescent techniques.
Thyroid Diseases
Incidence, predictability, and pathogenesis of amiodarone-induced thyrotoxicosis and hypothyroidism.
Thyroid Diseases
Induction of thyroid autoantibody production: synergistic effect of B cell mitogen combined with T cell mitogen.
Thyroid Diseases
Interaction of highly purified thyroid peroxidase with anti-microsomal antibodies in autoimmune thyroid diseases.
Thyroid Diseases
Isolation of a complementary DNA clone for thyroid microsomal antigen. Homology with the gene for thyroid peroxidase.
Thyroid Diseases
Mapping of a linear autoantigenic epitope within the human thyroid peroxidase using recombinant DNA techniques.
Thyroid Diseases
Measurement of circulating thyroid microsomal antibodies by the tanned red cell haemagglutination technique: its usefulness in the diagnosis of autoimmune thyroid diseases.
Thyroid Diseases
Patients with endocrine ophthalmopathy not associated with overt thyroid disease have multiple thyroid immunological abnormalities.
Thyroid Diseases
Performance of two agglutination techniques in the detection of thyroid antibodies and assessment of their clinical significance.
Thyroid Diseases
Peripheral blood T lymphocyte sensitization to thyroid microsomal antigen from patients with Graves' disease negative for circulating anti-thyroid microsomal antibodies.
Thyroid Diseases
Prevalence of abnormal thyrotropin concentrations measured by a sensitive assay in patients with type 2 diabetes mellitus.
Thyroid Diseases
Prevalence of antithyroid microsomal antibody in thyroid patients of endemic goitre area.
Thyroid Diseases
Purification of the human thyroid peroxidase and its identification as the microsomal antigen involved in autoimmune thyroid diseases.
Thyroid Diseases
Reduced activation of suppressor T lymphocytes by specific antigens in autoimmune thyroid disease.
Thyroid Diseases
Serum antibodies reactive with eye muscle membrane antigens are detected in patients with nonspecific orbital inflammation.
Thyroid Diseases
Studies of the effect of suppressor T lymphocytes on the induction of antithyroid microsomal antibody-secreting cells in autoimmune thyroid disease.
Thyroid Diseases
Studies with purified human thyroid peroxidase and thyroid microsomal autoantibodies.
Thyroid Diseases
Surface markers and function of circulating thyroid autoantibody-producing cells.
Thyroid Diseases
T cell regulation of thyroglobulin autoantibody IgG subclasses in Hashimoto's thyroiditis.
Thyroid Diseases
Thyroid autoantibodies in black and in white children and adolescents with type 1 diabetes mellitus and their first degree relatives.
Thyroid Diseases
Thyroid microsomal antigen in Graves' thyroid is not different from that in normal thyroid.
Thyroid Diseases
Thyroid microsomal/thyroid peroxidase autoantibodies show discrete patterns of cross-reactivity to myeloperoxidase, lactoperoxidase and horseradish peroxidase.
Thyroid Diseases
Thyroid-stimulating immunoglobulins in insulin-dependent diabetes mellitus.
Thyroid Diseases
TSH receptor antibody-associated thyroid dysfunction following subacute thyroiditis.
Thyroid Diseases
Use of recombinant epitopes to study the heterogeneous nature of the autoantibodies against thyroid peroxidase in autoimmune thyroid disease.
Thyroid Diseases
[An immunoenzyme method for determining autoantibodies to the microsomal antigens of human thyrocytes]
Thyroid Diseases
[Antigenic relation between thyroid peroxidase and the microsomal antigen implicated in auto-immune diseases of the thyroid]
Thyroid Diseases
[Detection of anti-thyroid plasma membrane antibody in patients with various thyroid diseases by solid phase enzyme-immunoassay]
Thyroid Diseases
[The significance of microsomal antibodies, thyroglobulin antibodies, thyrotropin receptor antibodies in the diagnosis of thyroid diseases]
Thyroid Diseases
[Thyroid antibodies in autoimmune diseases of the thyroid and their dependence on the presence of autoantigens]
Thyroid Diseases
[Thyroid microsomal autoantibodies in thyroid disease: their value as an antigenic marker]
Thyroid Neoplasms
Characterization of the thyroid microsomal antigen, and its relationship to thyroid peroxidase, using monoclonal antibodies.
Thyroid Neoplasms
Common precursor molecule as origin for the ectopic-hormone-producing-tumour syndrome.
Thyroid Neoplasms
Identification of Enzymes Oxidizing the Tyrosine Kinase Inhibitor Cabozantinib: Cabozantinib Is Predominantly Oxidized by CYP3A4 and Its Oxidation Is Stimulated by cyt b5 Activity.
Thyroid Neoplasms
Identification of procalcitonin in a rat medullary thyroid carcinoma cell line.
Thyroid Neoplasms
Measurement and clinical significance of thyroid microsomal and thyroglobulin antibodies by enzyme-linked immunosorbent assay.
Thyroid Neoplasms
Promotion of thyroid tumors in rats by pregnenolone-16alpha-carbonitrile (PCN) and polychlorinated biphenyl (PCB).
Thyroid Neoplasms
Rat pre-prosomatostatin. Structure and processing by microsomal membranes.
Thyroid Neoplasms
Serum autoantibodies and thyroid lymphocytic infiltration in endemic goitre.
Thyroid Neoplasms
Thyroid autoantibodies in thyroid cancer: incidence and relationship with tumour outcome.
Thyroid Neoplasms
Thyroid disease is associated with an increased risk of breast cancer: a systematic review and meta-analysis.
Thyroid Nodule
Ca(2+)/nicotinamide adenine dinucleotide phosphate-dependent H(2)O(2) generation is inhibited by iodide in human thyroids.
Thyroiditis
A case of acetohexamide-induced hypoglycemia: the influence of hypothyroidism on the metabolism of acetohexamide.
Thyroiditis
A simple semiquantitative radiometric measurement of antithyroglobulin antibodies in human serum. Comparison with hemagglutination method.
Thyroiditis
Age-related changes of thyroid function and immunologic abnormalities in patients with hyperthyroidism due to Graves' disease.
Thyroiditis
Anterior pituitary cell antibodies detected in Hashimoto's thyroiditis and Graves' disease.
Thyroiditis
Antibodies to human thyroid peroxidase in autoimmune thyroid disease: studies with a cloned recombinant complementary deoxyribonucleic acid epitope.
Thyroiditis
Antithyroid microsomal autoantibodies and HLA-DR5 are associated with postpartum thyroid dysfunction: evidence supporting an autoimmune pathogenesis.
Thyroiditis
Clinical evaluation of a hemagglutination method for microsomal and thyroglobulin antibodies in autoimmune thyroid disease.
Thyroiditis
Comparison of autoantibodies level in thyroid autoimmune diseases estimated by different methods.
Thyroiditis
Detection of autoantibodies to thyroid peroxidase in autoimmune thyroid diseases by micro-ELISA and immunoblotting.
Thyroiditis
Expression of the microsomal antigen on the surface of continuously cultured rat thyroid cells is modulated by thyrotropin.
Thyroiditis
Graves' disease and Hashimoto's thyroiditis: effects of high doses of antithyroid drugs on thyroid autoantibody levels.
Thyroiditis
Hashimoto's thyroiditis and papillary carcinoma in an adolescent girl: A case report.
Thyroiditis
Helicobacter pylori infection is markedly increased in patients with autoimmune atrophic thyroiditis.
Thyroiditis
High prevalence of thyroid autoantibodies in a prospective series of patients with chronic hepatitis C before interferon therapy.
Thyroiditis
Imatinib-induced thyroiditis in Philadelphia chromosome-positive chronic myeloid leukemia.
Thyroiditis
L-thyroxine therapy induces a fall of thyroid microsomal and thyroglobulin antibodies in idiopathic myxedema and in hypothyroid, but not in euthyroid Hashimoto's thyroiditis.
Thyroiditis
Localized primary amyloid tumor of the thyroid developing in the course of Hashimoto's thyroiditis.
Thyroiditis
Measurement and clinical significance of thyroid microsomal and thyroglobulin antibodies by enzyme-linked immunosorbent assay.
Thyroiditis
Mixed connective tissue disease associated with idiopathic portal hypertension and chronic thyroiditis.
Thyroiditis
Performance of two agglutination techniques in the detection of thyroid antibodies and assessment of their clinical significance.
Thyroiditis
Possible induction of Graves' disease and painless thyroiditis by gonadotropin-releasing hormone analogues.
Thyroiditis
Serum thyroglobulin concentration as an indicator for assessing thyroid stimulation in patients with Graves' disease during antithyroid drug therapy.
Thyroiditis
The association between thyroid echogenicity and thyroid function in pediatric and adolescent Hashimoto's thyroiditis.
Thyroiditis
Thyroid autoantigens and their relevance in the pathogenesis of thyroid autoimmunity.
Thyroiditis
Thyroxine, methimazole, and thyroid microsomal autoantibody titres in hypothyroid Hashimoto's thyroiditis.
Thyroiditis
[A case of Hashimoto's encephalopathy with a relapsing course related to menstrual cycle]
Thyroiditis
[A long-term follow-up study of patients with chronic lymphocytic thyroiditis--with special reference to histological findings]
Thyroiditis
[Chronic lymphocytic autoimmune thyroiditis: a commonly occurring thyroid disease]
Thyroiditis
[Effect of moxibustion on the antibody-dependent cell-mediated cytotoxicity activity in peripheral blood of patients with Hashimoto's thyroiditis]
Thyroiditis
[Subclinical hypothyroidism: a diagnostic and therapeutic approach in primary care]
Thyroiditis
[The clinical serological tests in chronic thyroiditis: the importance of measurement of anti-thyroid microsomal antibodies (author's transl)]
Thyroiditis, Autoimmune
Anti-thyroid microsomal antibody in synovial fluid as a revealing feature of seronegative autoimmune thyroiditis.
Thyroiditis, Autoimmune
Asymptomatic autoimmune thyroiditis and thyroid dysfunction in Alport's syndrome. A report of three families.
Thyroiditis, Autoimmune
Changes of serum anti-thyroid antibodies during and after pregnancy in autoimmune thyroid diseases.
Thyroiditis, Autoimmune
Free thyroxin index and direct measurements of free thyroxin compared for evaluating postpartum autoimmune thyroid dysfunction.
Thyroiditis, Autoimmune
Hemoglobin, iron, and vitamin B12 deficiencies and high blood homocysteine levels in patients with anti-thyroid autoantibodies.
Thyroiditis, Autoimmune
Improving iodine nutritional status and increasing prevalence of autoimmune thyroiditis in children.
Thyroiditis, Autoimmune
Isolation of thyroid peroxidase and lack of autoantibodies to the enzyme in dogs with autoimmune thyroid disease.
Thyroiditis, Autoimmune
Multiple pulmonary hyalinizing granulomas associated with systemic idiopathic fibrosis.
Thyroiditis, Autoimmune
Postpartum activation of autoimmunity: transient increase of total IgG levels in normal women and in women with autoimmune thyroiditis.
Thyroiditis, Autoimmune
Restricted heterogeneity and T cell dependence of human thyroid autoantibody immunoglobulin G subclasses.
Thyroiditis, Autoimmune
Thyroid autoimmunity in children and adolescents with Type 1 diabetes mellitus.
Thyroiditis, Autoimmune
Thyroid peroxidase antibodies in children with autoimmune thyroiditis.
Thyroiditis, Autoimmune
[Antibodies to the thyroid microsomal antigen in children and adolescents subjected to radiation exposure as a result of the accident at the Chernobyl Atomic Electric Power Station]
Thyroiditis, Subacute
Measurement and clinical significance of thyroid microsomal and thyroglobulin antibodies by enzyme-linked immunosorbent assay.
Thyrotoxicosis
Aggravation of thyrotoxicosis in early pregnancy and after delivery in Graves' disease.
Thyrotoxicosis
Five patients with painless thyroiditis simultaneously developed in a nursery school.
Thyrotoxicosis
Presence of the organ-specific 'microsomal' autoantigen on the surface of human thyroid cells in culture: its involvement in complement-mediated cytotoxicity.
Toxocariasis
[Investigation of the presence of autoantibodies in patients with toxocariasis]
Tremor
The pharmacology of N-carbamoyl-2-(2,6-dichlorophenyl)acetamidine hydrochloride (LON-954) a new tremorogenic agent.
Trigeminal Neuralgia
Ellagic acid enhances the antinociceptive action of carbamazepine in the acetic acid writhing test with mice.
Trigeminal Neuralgia
Tipepidine enhances the antinociceptive-like action of carbamazepine in the acetic acid writhing test.
Triple Negative Breast Neoplasms
Piperlongumine for Enhancing Oral Bioavailability and Cytotoxicity of Docetaxel in Triple-Negative Breast Cancer.
Trypanosomiasis
Hepatic microsomal alterations during chronic trypanosomiasis in the field vole, Microtus montanus.
Tuberculosis
6-Nitro-2,3-dihydroimidazo[2,1-b][1,3]thiazoles: Facile synthesis and comparative appraisal against tuberculosis and neglected tropical diseases.
Tuberculosis
Bifunctional T-cell-derived cytokines for the diagnosis of tuberculosis and treatment monitoring.
Tuberculosis
Crystal structures of Trypanosoma brucei sterol 14alpha-demethylase and implications for selective treatment of human infections.
Tuberculosis
Design, synthesis and biological evaluation of indole-2-carboxamides, a promising class of anti-tuberculosis agents.
Tuberculosis
Drug metabolism in experimental tuberculosis: I. Changes in hepatic and pulmonary monooxygenase activities due to infection.
Tuberculosis
Effect of cord factor, a toxic glycolipid from Mycobacterium tuberculosis, on mouse liver drug metabolizing enzymes.
Tuberculosis
Oxidative stress in the molecular mechanism of pathogenesis at different diseased states of organism in clinics and experiment.
Tuberculosis
Structure-Activity Relationships of Spectinamide Antituberculosis Agents: A Dissection of Ribosomal Inhibition and Native Efflux Avoidance Contributions.
Tuberculosis
The effect of adjuvant-induced arthritis on rat liver microsomal phospholipid metabolism.
Tuberculosis
TISSUE METABOLISM IN INFECTION. LIVER MICROSOMAL ENZYMES OF MICE AND GUINEA PIGS IN EXPERIMENTAL TUBERCULOSIS.
Tuberculosis
[Effect of antitubercular preparations on the isoform composition of cytochrome P-450 of rat liver microsomes]
Typhoid Fever
[Effect of inducers and inhibitors of mixed function oxidases on body resistance to endotoxins of gram-negative bacteria]
unspecific monooxygenase deficiency
CYP2E1 and CYP4A as microsomal catalysts of lipid peroxides in murine nonalcoholic steatohepatitis.
Uremia
Effect of uremia on rates of ethanol disappearance from the blood and on the activities of the ethanol-oxidizing enzymes.
Uremia
The effects of acute and chronic uremia in rats on their hepatic microsomal enzyme activity.
Urinary Bladder Neoplasms
Co2+ is able to substitute for Mn2+ in some exogenous and endogenous galactosyltransferase reactions.
Urinary Bladder Neoplasms
Combined analysis of inherited polymorphisms in arylamine N-acetyltransferase 2, glutathione S-transferases M1 and T1, microsomal epoxide hydrolase, and cytochrome P450 enzymes as modulators of bladder cancer risk.
Urinary Bladder Neoplasms
Genetic polymorphisms of cytochrome P450 CYP1A1 (*2A) and microsomal epoxide hydrolase gene, interactions with tobacco-users, and susceptibility to bladder cancer: a study from North India.
Urinary Bladder Neoplasms
Global Identification and Differential Distribution Analysis of Glycans in Subcellular Fractions of Bladder Cells.
Urticaria
Correlation of serum antithyroid microsomal antibody and autologous serum skin test in patients with chronic idiopathic urticaria.
Urticaria
Steroid-resistant chronic urticaria associated with anti-thyroid microsomal antibodies in a nine-year-old boy.
Vascular Diseases
Gene activation, apolipoprotein A-I/high density lipoprotein, atherosclerosis prevention and longevity.
Vascular Diseases
Plasma high-density lipoproteins and hepatic microsomal enzyme induction. Relation to histological changes in the liver.
Vesicular Stomatitis
Cell-free fatty acylation of microsomal integrated and detergent-solubilized glycoprotein of vesicular stomatitis virus.
Vesicular Stomatitis
Translation of vesicular stomatitis and Sindbis virus mRNAs in cell-free extracts of Aedes albopictus cells.
Viremia
Interferon therapy in liver/kidney microsomal antibody type 1-positive patients with chronic hepatitis C.
Viremia
Low hepatitis C viremia levels in patients with anti-liver/kidney microsomal antibody type 1 positive chronic hepatitis.
Viremia
Quantitative analysis of hepatitis C virus activity in vivo in different groups of untreated patients.
Virus Diseases
A novel assay for detecting antibodies to cytochrome P4502D6, the molecular target of liver kidney microsomal antibody type 1.
Virus Diseases
Anti-rat liver microsomal and cytosolic antibodies in hepatitis C virus infection.
Virus Diseases
Antigen-loaded ER microsomes from APC induce potent immune responses against viral infection.
Virus Diseases
Development of monoclonal antibodies to human microsomal epoxide hydrolase and analysis of "preneoplastic antigen"-like molecules.
Virus Diseases
Differences in immune recognition of cytochrome P4502D6 by liver kidney microsomal (LKM) antibody in autoimmune hepatitis and chronic hepatitis C virus infection.
Virus Diseases
Establishment of a novel radioligand assay using eukaryotically expressed cytochrome P4502D6 for the measurement of liver kidney microsomal type 1 antibody in patients with autoimmune hepatitis and hepatitis C virus infection.
Virus Diseases
Hepatitis C virus infection associated with liver-kidney microsomal antibody type 1 (LKM1) autoantibodies in children.
Virus Diseases
Hepatitis C virus-related chronic liver disease with autoantibodies to liver-kidney microsomes (LKM). Clinical characterization from idiopathic LKM-positive disorders.
Virus Diseases
Heterogeneity of liver-kidney microsomal autoantibodies in chronic hepatitis C and D virus infection.
Virus Diseases
Interferon therapy in liver/kidney microsomal antibody type 1-positive patients with chronic hepatitis C.
Virus Diseases
Liver kidney microsomal type 1 antibodies reduce the CYP2D6 activity in patients with chronic hepatitis C virus infection.
Virus Diseases
Low hepatitis C viremia levels in patients with anti-liver/kidney microsomal antibody type 1 positive chronic hepatitis.
Virus Diseases
Modulatory effect of hyperthermia on hepatic microsomal cytochrome P450 in mice.
Virus Diseases
Recurrent episodes of acute hepatitis associated with LKM-1 (cytochrome P450 2D6) antibodies in identical twin brothers.
Vitamin A Deficiency
Effect of vitamin A deficiency on hepatic microsomal and colon mucosal mixed function oxidase. IV--Influence on aflatoxin B1 metabolism, ethylmorphine and epoxide hydrase activity.
Vitamin A Deficiency
Effect of vitamin A on rat hepatic mixed-function oxidases, glutathione transferase activity and generations of oxygen radicals.
Vitamin A Deficiency
Lipid peroxidation and benzo[a]pyrene activation to mutagenic metabolites: in vivo influence of vitamins A, E and C and glutathione in both dietary vitamin A sufficiency and deficiency.
Vitamin A Deficiency
Restoration of cytochrome P450 2C11 in vitamin A-deficient rat liver by exogenous androgen.
Vitamin A Deficiency
Suppression of the constitutive microsomal cytochrome P450 2C11 in male rat liver during dietary vitamin A deficiency.
Vitamin A Deficiency
Synthesis of retinyl phosphate mannose and dolichyl phosphate mannose from endogenous and exogenous retinyl phosphate and dolichyl phosphate in microsomal fraction. Specific decrease in endogenous retinyl phosphate mannose synthesis in vitamin A deficiency.
Vitamin A Deficiency
The differential effects of chemical carcinogens on vitamin A status and on microsomal drug metabolism in normal and vitamin A-deficient rats.
Vitamin A Deficiency
[Lipid peroxidation in the rat liver in mild forms of vitamin A deficiency]
Vitamin A Deficiency
[Vitamin A and microsomal membranes: the effect of retinol deficiency on lipid microviscosity and phospholipid turnover in rat liver microsomes]
Vitamin D Deficiency
Mutation of the CYP2R1 Vitamin D 25-Hydroxylase in a Saudi Arabian Family with Severe Vitamin D Deficiency.
Vitamin E Deficiency
Alteration of brain and liver microsomal polyunsaturated fatty acids following dietary vitamin E deficiency.
Vitamin E Deficiency
Effects of selenium and vitamin E deficiencies in lambs on hepatic microsomal hemoproteins and mitochondrial respiration.
Vitamin E Deficiency
Effects of vitamin E deficiency on hepatic microsomal cytochrome P450 and phase II enzymes in male and female rats.
Vitamin E Deficiency
Influence of vitamin E and nitrogen dioxide on lipid peroxidation in rat lung and liver microsomes.
Vitamin E Deficiency
The dependence on vitamin E and selenium of drug demethylation in rat liver microsomal fractions.
Vitamin E Deficiency
Vitamin E, membrane order, and antioxidant behavior in lung microsomes and reconstituted lipid vesicles.
Vitamin K Deficiency
[Activity of enzymes participating in xenobiotic metabolism and the condition of microsomal membranes of rat liver in vitamin K deficiency]
Vitiligo
Chronic active hepatitis associated with vitiligo, nail dystrophy, alopecia and a new variant of LKM antibodies.
Vitiligo
Incidence and significance of organ-specific autoimmune disorders (clinical, latent or only autoantibodies) in patients with vitiligo.
Whooping Cough
Depression of hepatic drug-metabolizing enzyme activity by B. pertussis vaccination.
Whooping Cough
Depression of hepatic mixed-function oxidase activity by B. pertussis in splenectomized and athymic nude mice.
Whooping Cough
Muscarinic acetylcholine receptors in the sino-atrial node and right atrium of bovine heart.
Whooping Cough
Rapid activation of phosphatidate phosphohydrolase in mesangial cells by lipid A.
Whooping Cough
Thrombin-induced prostacyclin biosynthesis in human endothelium: role of guanine nucleotide regulatory proteins in stimulus/coupling responses.
Xanthomatosis
Competitive inhibition of bile acid synthesis by endogenous cholestanol and sitosterol in sitosterolemia with xanthomatosis. Effect on cholesterol 7 alpha-hydroxylase.
Xanthomatosis, Cerebrotendinous
Biosynthesis of bile acids in cerebrotendinous xanthomatosis. Relationship of bile acid pool sizes and synthesis rates to hydroxylations at C-12, C-25, and C-26.
Xanthomatosis, Cerebrotendinous
Transformation of 4-cholesten-3-one and 7 alpha-hydroxy-4-cholesten-3-one into cholestanol and bile acids in cerebrotendinous xanthomatosis.
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