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Disease on EC 3.2.1.31 - beta-glucuronidase

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DISEASE
TITLE OF PUBLICATION
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Aberrant Crypt Foci
Effects of Shikunshito-Kamiho on fecal enzymes and formation of aberrant crypt foci induced by 1,2-dimethylhydrazine.
Inhibitory effect of Bifidobacterium longum cultures on the azoxymethane-induced aberrant crypt foci formation and fecal bacterial beta-glucuronidase.
The influence of flaxseed and lignans on colon carcinogenesis and beta-glucuronidase activity.
Acalculous Cholecystitis
Gallbladder epithelial acid hydrolases in human cholecystitis.
Acidosis
Acidosis inhibits osteoblastic and stimulates osteoclastic activity in vitro.
Additive effects of acidosis and parathyroid hormone on mouse osteoblastic and osteoclastic function.
Coordinately increased lysozymuria and lysosomal enzymuria induced by maleic acid.
Stimulated osteoclastic and suppressed osteoblastic activity in metabolic but not respiratory acidosis.
Acidosis, Renal Tubular
Coordinately increased lysozymuria and lysosomal enzymuria induced by maleic acid.
Acidosis, Respiratory
Stimulated osteoclastic and suppressed osteoblastic activity in metabolic but not respiratory acidosis.
Acne Conglobata
Transient absence of C5a-specific neutrophil function in inflammatory disorders of the skin.
Acquired Immunodeficiency Syndrome
Elevated serum beta-glucuronidase activity in acquired immunodeficiency syndrome.
Enzymic methods for estimation of the somatic cell count in bovine milk. 1. Development of assay techniques and a study of their usefulness in evaluating the somatic cell content of milk.
Adenocarcinoma
Alteration in glycosidases from well-differentiated colorectal adenocarcinoma of rat.
Cancer-associated alteration of beta-glucuronidase in human lung cancer: elevated activity and increased phosphorylation.
Enzyme activity and distribution in rat prostatic adenocarcinoma.
Enzymorphology of adenocarcinoma of the endometrium; beta-glucuronidase, acid phosphatase, reduced diphosphopyridine nucleotide (DPNH) diaphorase, and alpha-naphthyl esterase.
Expression and function of beta-glucuronidase in pancreatic cancer: potential role in drug targeting.
Response of a high-glucuronidase human tumour xenograft to aniline mustard.
The cytochemical demonstration of beta-glucuronidase in colon neoplasms of rats exposed to azoxymethane.
[beta-Glucuronidase in human maxillary sinus and lung cancers: elevation of activity level and appearance of phosphorylated variant forms]
Adenocarcinoma of Lung
[beta-Glucuronidase in human maxillary sinus and lung cancers: elevation of activity level and appearance of phosphorylated variant forms]
Adenocarcinoma, Mucinous
The cytochemical demonstration of beta-glucuronidase in colon neoplasms of rats exposed to azoxymethane.
Adenoma
Wheat aleurone flour increases cecal beta-glucuronidase activity and butyrate concentration and reduces colon adenoma burden in azoxymethane-treated rats.
Aggressive Periodontitis
Analysis of human gingival tissue and gingival crevicular fluid beta-glucuronidase activity in specific periodontal diseases.
BETA-GLUCURONIDASE AND ASCORBIC ACID LEVELS IN PERIODONTOSIS.
Crevicular fluid level of beta-glucuronidase in relation to clinical periodontal parameters and putative periodontal pathogens in early-onset periodontitis.
Albuminuria
Organic solvents and chronic glomerulonephritis: a cross-sectional study with negative findings for aliphatic and alicyclic C5-C7 hydrocarbons.
Alkalosis
Metabolic alkalosis decreases bone calcium efflux by suppressing osteoclasts and stimulating osteoblasts.
Altitude Sickness
[The effect of high altitude hypoxia and decreased external temperature on the levels of complement, lysozyme and beta-D-glucuronidase in the blood, spleen and liver of rats]
Alzheimer Disease
Cortical glutaminase, beta-glucuronidase and glucose utilization in Alzheimer's disease.
Invited review: Bovine milk fat globule membrane as a potential nutraceutical.
Amyotrophic Lateral Sclerosis
Lysosomal and nonlysosomal hydrolases of skeletal muscle in neuromuscular diseases.
Anaphylaxis
Antiallergic and anti-inflammatory action of tioxamast in rats. I. Antiallergic activity in vivo and in vitro.
[Platelets, lysosomal enzymes and anaphylactic shock in the rat]
Anaplasia
[Histochemical demonstration of glial enzyme activity. II. Reagent and neoplastic glia]
Androgen-Insensitivity Syndrome
More about X-linked testicular feminization of the mouse as a noninducible(is)mutation of a regulatory locus: 5-alpha-androstan-3-alpha-17-beta-diol as the true inducer of kidney alcohol dehydrogenase and beta-glucuronidase.
Anemia
Decreased urinary excretion of beta-glucuronidase in sickle cell anemia in Nigeria.
The activity of certain hydrolases of rat erythrocytes in experimental magnesium deficiency.
The occurrence of beta-glucuronidase in erythrocyte inclusions.
[Activity of selected neutrophil enzymes of patients maintained on hemodialysis and treated with erythropoietin (rHu EPO)]
Anemia, Dyserythropoietic, Congenital
The occurrence of beta-glucuronidase in erythrocyte inclusions.
Anemia, Sickle Cell
Decreased urinary excretion of beta-glucuronidase in sickle cell anemia in Nigeria.
Arteriosclerosis
Increased aortic beta-glucuronidase activity with progressively severe arteriosclerosis in female breeder rats.
[Diagnostic evidence of serum beta-glucuronidase. IV. Serum beta glucuronidase activity in arteriosclerosis and diabetes mellitus]
[Serum beta-glucuronidase in arteriosclerosis]
Arthritis
Comparative studies on the effects of erythromycin A and azithromycin upon extracellular release of lysosomal enzymes in inflammatory processes.
Dextran sulphate induced arthritis in rabbits.
Effect of bioflavonoids on lysosomal acid hydrolases and lysosomal stability in adjuvant-induced arthritis.
Glucuronidation of R- and S-ketoprofen, acetaminophen, and diflunisal by liver microsomes of adjuvant-induced arthritic rats.
[Activity of acid hydrolases in rat tissues under experimental arthritis]
[Serum level of beta-glucuronidase as potential indicator of disease activity in rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE)]
Arthritis, Experimental
Levels of collagenolytic activity, beta-glucuronidase, and collagen prolyl hydroxylase in paws from rats with developing adjuvant arthritis.
Proteolytic and beta-glucuronidase activity in adjuvant arthritis during the ibuprofen therapy.
[Activity of acid hydrolases in rat tissues under experimental arthritis]
Arthritis, Rheumatoid
Activity of lysosomal exoglycosidases in serum and synovial fluid in patients with chronic Lyme and rheumatoid arthritis.
Activity of some lysosomal enzyme in rheumatoid and psoriatic arthritis.
Cyclosporin treatment in rheumatoid arthritis is associated with an increased serum activity of beta-glucuronidase.
Gene expression and activity of cartilage-degrading glycosidases in human rheumatoid arthritis and osteoarthritis synovial fibroblasts.
Levels of plasma beta-glucuronidase in rheumatoid arthritis.
Synovial fluid exoglycosidases are predictors of rheumatoid arthritis and are effective in cartilage glycosaminoglycan depletion.
The effect of D-penicillamine on polymorphonuclear leukocyte function.
[Activity of beta-glucuronidase in the synovial fluid in rheumatoid arthritis and degenerative joint diseases]
[Clinical value of determining beta-glucuronidase and glycosaminoglycans in blood cells and biological fluids in patients with rheumatoid arthritis]
[Effect of 1-hour administration of dimethyl sulfoxide on the levels of prostaglandins, products of lipid peroxidation and beta-glucuronidase activity in the blood of patients with rheumatoid arthritis]
[Effect of a beta-glucuronidase inhibitor (2,5-di-O-acetyl-D-glucuro-diláctone and sodium D-glucurolactonate) on rheumatoid arthritis]
[Glycosaminoglycans and beta-glucuronidase in peripheral blood cells and biological fluids of patients with rheumatoid arthritis]
[Importance of beta-glucuronidase activity and glycosaminoglycan concentration in synovial fluid in patients with rheumatoid arthritis in estimating local inflammation]
[Serum level of beta-glucuronidase as potential indicator of disease activity in rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE)]
[Studies on enzyme activities in chronic rheumatoid arthritis. On beta-N-acetyl-glucosaminidase, beta-glucuronidase and their inhibitors]
Arthus Reaction
Histoenzymology of the lung. II. The behaviour of lung hydrolytic enzymes during some experimental pulmonary processes.
[Effect of KP-136 on allergic paw edema in the rat]
Asbestosis
Serum lysosomal enzyme activities in silicosis and asbestosis.
Asthma
A double-blind randomized placebo-controlled trial with short-term beta-glucuronidase therapy in children with chronic rhinoconjunctivitis and/or asthma due to dust mite allergy.
[In vitro Intal effect on the activity of beta-glucuronidase and acid phosphatase of leukocytes in patients with asthma]
[The influence of climatic treatment on the levels of complement and some lysosomal enzymes in serum of patients with asthma bronchiale (author's transl)]
Astrocytoma
Increased activity of lysosomal glycohydrolases in glioma tissue and surrounding areas from human brain.
Atherosclerosis
Atherosclerosis and beta-glucuronidase.
Beta-Glucuronidase Activity in Serum Increased by Coronary-Artery Atherosclerosis.
beta-glucuronidase activity of the aorta in early stages of experimental rabbit atherosclerosis.
Beta-glucuronidase and atherosclerosis.
Serum beta-glucuronidase activity of various species: possible correlation with susceptibility to atherosclerosis.
[The activity of phosphomonoesterase, carboxylesterase, lactate dehydrogenase and beta-glucuronidase in blood serum, liver, kidney and aorta in rabbit atherosclerosis]
[The effect of beta-glucuronidase on the development of experimental atherosclerosis]
Bacterial Infections
Atopic dermatitis: influence of bacterial infections on human monocyte and neutrophil granulocyte functional activities.
Beta-glucuronidase release from leukocytes in children.
[The changes of beta-glucuronidase in rabbit model with calcium bilirubinate stone]
beta-glucuronidase deficiency
A pseudodeficiency allele (D152N) of the human beta-glucuronidase gene.
Atypical radiological features of beta-glucuronidase deficiency (mucopolysaccharidosis VII) occurring in an elderly patient from an inbred kindred.
Beta-glucuronidase deficiency (mucopolysaccharidosis type VII).
beta-Glucuronidase deficiency as a cause of fetal hydrops.
Beta-glucuronidase deficiency as a cause of prenatally diagnosed non-immune hydrops fetalis.
Beta-glucuronidase deficiency as cause of recurrent hydrops fetalis: the first early prenatal diagnosis by chorionic villus sampling.
Beta-glucuronidase deficiency in a dog: a model of human mucopolysaccharidosis VII.
Beta-glucuronidase deficiency in a girl with unusual clinical features.
Beta-glucuronidase deficiency mucopolysaccharidosis.
Beta-glucuronidase deficiency mucopolysaccharidosis. Repository identification No. GM-121.
Beta-glucuronidase deficiency mucopolysaccharidosis: methods for enzymatic diagnosis.
Beta-glucuronidase deficiency. A heterogeneous mucopolysaccharidosis.
Beta-glucuronidase deficiency: enzyme studies in an affected family and prenatal diagnosis.
beta-Glucuronidase deficiency: identification of an affected fetus with simultaneous sampling of chorionic villus and amniotic fluid.
Cross-correction of beta-glucuronidase deficiency by retroviral vector-mediated gene transfer.
Detection of active heteropolymeric beta-glucuronidase in hybrids between mouse cells and human fibroblasts with beta-glucuronidase deficiency.
Extensive beta-glucuronidase activity in murine central nervous system after adenovirus-mediated gene transfer to brain.
Feline mucopolysaccharidosis VII due to beta-glucuronidase deficiency.
Functional correction of CNS phenotypes in a lysosomal storage disease model using adeno-associated virus type 4 vectors.
Gene therapy/cell therapy for lysosomal storage disease.
Human beta-glucuronidase deficiency mucopolysaccharidosis: identification of cross-reactive antigen in cultured fibroblasts of deficient patients by enzyme immunoassay.
Identification and functional analysis of genetic variants of the human beta-glucuronidase in a German population sample.
Identification of new markers for neurodegeneration process in the mouse model of Sly disease as revealed by expression profiling of selected genes.
Incidence of the mucopolysaccharidoses in Northern Ireland.
Intracisternal A-particle element transposition into the murine beta-glucuronidase gene correlates with loss of enzyme activity: a new model for beta-glucuronidase deficiency in the C3H mouse.
Lymphocytes, neutrophils and serum immunoglobulins in patients with precancerous states of the larynx.
Lysosomal storage diseases presenting as transient or persistent hydrops fetalis.
Molecular analysis of a patient with hydrops fetalis caused by beta-glucuronidase deficiency, and evidence for additional pseudogenes.
Molecular analysis of patients with beta-glucuronidase deficiency presenting as hydrops fetalis or as early mucopolysaccharidosis VII.
Molecular basis of feline beta-glucuronidase deficiency: an animal model of mucopolysaccharidosis VII.
Mucopolysaccharidosis type VII as a cause of recurrent non-immune hydrops fetalis.
Mucopolysaccharidosis type VII in a German Shepherd Dog.
Mucopolysaccharidosis VII as cause of fetal hydrops in early pregnancy.
Mucopolysaccharidosis VII: postmortem biochemical and pathological findings in a young adult with beta-glucuronidase deficiency.
Mucopolysaccharidosis. VII. Beta-glucuronidase deficiency.
Murine mucopolysaccharidosis type VII. Characterization of a mouse with beta-glucuronidase deficiency.
Mutational analysis in longest known survivor of mucopolysaccharidosis type VII.
Mutational studies in a patient with the hydrops fetalis form of mucopolysaccharidosis type VII.
Non-immune hydrops fetalis caused by beta-glucuronidase deficiency (mucopolysaccharidosis VII). Study of a family with 3 affected siblings.
Nonablative neonatal marrow transplantation attenuates functional and physical defects of beta-glucuronidase deficiency.
Numerous transcriptional alterations in liver persist after short-term enzyme-replacement therapy in a murine model of mucopolysaccharidosis type VII.
Overexpression rescues the mutant phenotype of L176F mutation causing beta-glucuronidase deficiency mucopolysaccharidosis in two Mennonite siblings.
Phenotype correction in retinal pigment epithelium in murine mucopolysaccharidosis VII by adenovirus-mediated gene transfer.
Phenotypic expression in mucopolysaccharidosis VII.
Postmortem observations on beta-glucuronidase deficiency presenting as hydrops fetalis.
Rapid prenatal testing for human beta-glucuronidase deficiency (MPS VII).
Somatic gene therapy for a neurodegenerative disease using microencapsulated recombinant cells.
Storage correction in cells of patients suffering from mucopolysaccharidoses types IIIA and VII after treatment with genistein and other isoflavones.
The enzymatic equipment of neutrophils in patients with precancerous states of the larynx.
Treatment of lysosomal storage disorders: cell therapy and gene therapy.
Unusually mild course of beta-glucuronidase deficiency in two brothers (mucopolysaccharidosis VII).
Variation in the phenotypic expression of beta-glucuronidase deficiency.
[Beta-glucuronidase deficiency in the circulating neutrophils of patients with stationary simple psoriasis]
[Beta-glucuronidase deficiency in the peripheral neutrophils in diabetes mellitus]
[Mucopolysaccharidesis Type VII resulting from beta-glucuronidase deficiency. Report of one family]
Blast Crisis
Cytochemical studies in the blastic transformation of chronic granulocytic leukaemia.
Bone Cysts
The role of lysosomes in the pathogenesis of unicameral bone cysts.
Bone Diseases, Developmental
Enzyme replacement therapy improves reproductive performance in mucopolysaccharidosis type VII mice but does not prevent postnatal losses.
Bone Resorption
Alpha-difluoromethylornithine inhibits bone resorption in vitro without decreasing beta-glucuronidase release.
Aluminum action on mouse bone cell metabolism and response to PTH and 1,25(OH)2D3.
Effects of cholera toxin on cyclic AMP accumulation and bone resorption in cultured mouse calvaria.
Glucocorticoids stimulate resorption in fetal rat parietal bones in vitro.
Influence of diphenylhydantoin on lysosomal enzyme release during bone resorption in vitro.
Brain Diseases
Beta-glucuronidase activity, and levels of protein and protein fractions in serum and cerebrospinal fluid of dogs with distemper associated demyelinating encephalopathy.
Brain lysosomal glycosidase activity in immunosuppressed mice infected with avirulent Semliki forest virus.
Brain Edema
[A study of the optimum dose of a glucocorticoid, methylprednisolone sodium succinate, before and after neurosurgical major operations--relationship between beta-glucuronidase level and post operative brain edema]
Brain Neoplasms
Cytochemical distribution of beta-glucuronidase activity in experimental brain tumors and brain tissue in vivo and in vitro.
Measurements of CSF biochemical tumor markers in patients with meningeal carcinomatosis and brain tumors.
[Beta-glucuronidase activity of the cerebrospinal fluid of patients with brain tumors]
Breast Diseases
beta-Glucuronidase levels in patients with fibrocystic breast disease.
Breast Neoplasms
Beta-glucuronidase in human mammary carcinomas.
Characterization of the microbiome of nipple aspirate fluid of breast cancer survivors.
Enzymatic deficiencies of the immune system cells in patients with cancer of the larynx and other malignancies.
Inhibition of human breast cancer growth by GCP (genistein combined polysaccharide) in xenogeneic athymic mice: involvement of genistein biotransformation by beta-glucuronidase from tumor tissues.
Lysosomal enzymes of neutrophils in women with breast cancer.
Plasma beta-glucuronidase as an index of hormone dependency of breast tumours.
Plasma beta-glucuronidase levels in breast cancer.
Sensitivity and specificity of single and combined tumour markers in the diagnosis of leptomeningeal metastasis from breast cancer.
The role of beta-glucuronidase in induction of apoptosis by genistein combined polysaccharide (GCP) in xenogeneic mice bearing human mammary cancer cells.
[ACTIVITY OF BETA-GLUCURONIDASE IN THE BLOOD PLASMA OF WOMEN NORMAL AND WITH BREAST CANCER.]
[Activity of lysosomal alpha-arylsulfatase and beta-glucuronidase enzymes in benign and malignant breast tumors]
[beta-Glucuronidase and breast tumors.]
Bronchitis
Targeted protein accumulation promoted by autoassembly and its recovery from plant cells.
Z-membranes: artificial organelles for overexpressing recombinant integral membrane proteins.
Bronchopulmonary Dysplasia
Lysosomal enzymes in preterm infants with bronchopulmonary dysplasia: a potential diagnostic marker.
Carcinogenesis
A large-scale purification of beta-glucuronidase from human liver by immunoaffinity chromatography.
Anticarcinogenic action of apple pectin on fecal enzyme activities and mucosal or portal prostaglandin E2 levels in experimental rat colon carcinogenesis.
Cell-free whey from milk fermented with Bifidobacterium breve C50 used to modify the colonic microflora of healthy subjects.
Ceramide-beta-D-glucuronide: synthesis, digestion, and suppression of early markers of colon carcinogenesis.
Chemopreventative activity of dietary glucarate on azoxymethane-induced altered hepatic foci in rats.
Development and optimization of an enzyme-linked immunosorbent assay employing two murine monoclonal antibodies for absolute quantitation of human beta-glucuronidase.
Dietary glucarate-mediated reduction of sensitivity of murine strains to chemical carcinogenesis.
Differences in susceptibility of Arabidopsis ecotypes to crown gall disease may result from a deficiency in T-DNA integration.
Effect of beta-glucuronidase inhibitor on azoxymethane-induced colonic carcinogenesis in rats.
Effect of Bifidobacterium longum and inulin on gut bacterial metabolism and carcinogen-induced aberrant crypt foci in rats.
Effect of caloric restriction on aflatoxin B1-DNA adduct formation and associated factors in Fischer 344 rats: preliminary findings.
Effect of chronic ingestion of a fermented dairy product containing Lactobacillus acidophilus and Bifidobacterium bifidum on metabolic activities of the colonic flora in humans.
Effect of dietary fiber on the activity of intestinal and fecal beta-glucuronidase activity during 1,2-dimethylhydrazine induced colon carcinogenesis.
Effect of high-risk diets for colon carcinogenesis on intestinal mucosal and bacterial beta-glucuronidase activity in F344 rats.
Effects of apple pectin on fecal bacterial enzymes in azoxymethane-induced rat colon carcinogenesis.
Effects of beta-glucuronidase-deficient and lycopene-producing Escherichia coli strains on formation of azoxymethane-induced aberrant crypt foci in the rat colon.
Effects of differing purified cellulose, pectin, and hemicellulose fiber diets on fecal enzymes in 1,2-dimethylhydrazine-induced rat colon carcinogenesis.
Effects of Shikunshito-Kamiho on fecal enzymes and formation of aberrant crypt foci induced by 1,2-dimethylhydrazine.
Fenugreek affects the activity of beta-glucuronidase and mucinase in the colon.
Induction of beta-glucuronidase activity during dimethylhydrazine carcinogenesis and additive effects of cholic acid and indole.
Induction of colon mucosal beta-glucuronidase production as a mechanism for 1,2-dimethylhydrazine colon carcinogenesis.
Inhibition of 7,12-dimethylbenzanthracene-induced rat mammary tumorigenesis by 2,5-di-O-acetyl-D-glucaro-1,4:6,3-dilactone, an in vivo beta-glucuronidase inhibitor.
Metabolic conversion of dietary quercetin from its conjugate to active aglycone following the induction of hepatocarcinogenesis in fisher 344 rats.
Pancreatobiliary and biliary control of fecal beta-glucuronidase activity in the rat.
Protective role of luteolin in 1,2-dimethylhydrazine induced experimental colon carcinogenesis.
pSa causes oncogenic suppression of Agrobacterium by inhibiting VirE2 protein export.
Rapid purification of beta-glucuronidase from human liver by immunoaffinity chromatography employing specific murine monoclonal IgG binding to tresyl-activated agarose.
Role of schistosomiasis in human bladder cancer: evidence of association, aetiological factors, and basic mechanisms of carcinogenesis.
The influence of flaxseed and lignans on colon carcinogenesis and beta-glucuronidase activity.
[Increase of activity of urinary beta-glucuronidase in benzidine workers; first clinical contribution to the study of the correlation between enzymatic activity and bladder carcinogenesis.]
[New means for the prophylaxis of colon cancer with the use of beta-glucuronidase inhibitors]
Carcinoma
A monoclonal antibody-beta-glucuronidase conjugate as activator of the prodrug epirubicin-glucuronide for specific treatment of cancer.
beta-Glucoronidase and the gastric epithelial cell. A study using organ culture.
Beta-glucuronidase activity in gastric aspirate in gastric carcinoma.
Beta-glucuronidase activity in prostatic carcinoma and benign prostatic hyperplasia.
beta-Glucuronidase in gastric aspirate after oral cimetidine in the diagnosis of carcinoma of the stomach.
Beta-glucuronidase in human mammary carcinomas.
Beta-glucuronidase, gastritis, and gastric carcinoma.
Biochemical factors in the etiology of carcinoma of the bladder. The role of beta-glucuronidase.
Cancer-associated alteration of beta-glucuronidase in human lung cancer: elevated activity and increased phosphorylation.
Carcinocythemia (carcinoma cell leukemia). An acute leukemia-like picture due to metastatic carcinoma cells.
Cerebrospinal fluid biochemical markers of central nervous system metastases.
Comparison of enzyme phenotypes in human bladder tumours and experimentally induced hyperplastic and neoplastic lesions of the rat urinary bladder. A combined histochemical and immunohistochemical approach.
Construction and characterization of a fusion protein of single-chain anti-carcinoma antibody 323/A3 and human beta-glucuronidase.
Effect of macrophage activation by immunoadjuvants on serum levels of lysosomal hydrolases in mice.
Elevated gastric juice enzymes--a marker for increased gastric cancer risk?
Enzyme activity and distribution in rat prostatic adenocarcinoma.
Gene expression imaging by enzymatic catalysis of a fluorescent probe via membrane-anchored beta-glucuronidase.
Immunoliposomes as enzyme-carriers (immuno-enzymosomes) for antibody-directed enzyme prodrug therapy (ADEPT): optimization of prodrug activating capacity.
Inhibition of azoxymethane-induced rat colon carcinogenesis by potassium hydrogen D-glucarate.
Liposome-mediated targeting of enzymes to cancer cells for site-specific activation of prodrugs: comparison with the corresponding antibody-enzyme conjugate.
Local enzymatic hydrolysis of an endogenously generated metabolite can enhance CPT-11 anticancer efficacy.
Modified method for determination of serum beta-glucuronidase: A comparative study using P-nitrophenyl glucuronide and phenolphthalein glucuronide as substrate in gastrointestinal tract carcinomas.
Rapid method for localizing beta-glucuronidase in populations of human leucocytes and of mouse Ehrlich carcinoma cells.
Serum activities of lysosomal enzymes in patients with liver cell carcinoma.
Serum alkaline-stable acid thiol proteinase--a possible marker for primary liver carcinoma.
Studies of the activities of lysosomal enzymes in serum and buccal pouch tissue of hamsters during 7,12-dimethylbenz[a]anthracene-induced carcinogenesis.
The prognostic value of acid phosphatase and beta-glucuronidase activity in biopsy specimens from patients with reactivated prostatic cancer.
Urinary beta-glucuronidase in renal cell carcinoma.
Urinary beta-glucuronidase in screening and followup of primary urinary tract malignancy.
[A comparism between lysosomal enzyme activity in normal ectocervical squamous epithelium and squamous carcinoma of the ectocervix]
[Beta-glucuronidase in carcinoma of the bladder and effects of its inhibitor]
[beta-Glucuronidase in human maxillary sinus and lung cancers: elevation of activity level and appearance of phosphorylated variant forms]
[Beta-glucuronidase in the ascitic fluid and serum of mice with Ehrlich ascites carcinoma]
[Betaglucuronidase activity in ovarian carcinoma (author's transl)]
[Changes in beta-glucuronidase activity recognized in granulocytes from patients with carcinomas of the gastrointestinal tract]
[Enzyme levels and carcinoma treatment. 1. The serum beta-glucuronidase activity in patients with malignant gynecologic diseases before, during and after the clinical treatment]
[Enzymes in gastric juice. An aid in the diagnosis of gastric cancer]
[Histochemical studies on beta-glucuronidase activity in psoriasis, basilioma and spinocellular carcinoma.]
[Investigations into the clinical significance of beta-glucuronidase as tumour indicator during radiation therapy of patients with carcinoma of the bladder (author's transl)]
[Lysosomal beta-glucuronidase in lymphocytes of patients with gastric carcinoma]
[Proceedings: Activity of beta-glucuronidase in epithelial proliferation of the mammary gland especially in carcinoma]
[Serum beta-glucuronidase activity in polytrauma patients and in centrifuged autopsy blood samples]
[Various enzymatic activities in gastric carcinoma and intestinal metaplasia]
Carcinoma, Bronchogenic
Enhanced uptake of doxorubicin into bronchial carcinoma: beta-glucuronidase mediates release of doxorubicin from a glucuronide prodrug (HMR 1826) at the tumor site.
Carcinoma, Hepatocellular
Beta-glucuronidase activity of Yoshida ascites hepatomas of different drug-sensitivity and its change after treatment of host rats with various anticancer agents.
Beta-glucuronidase isozyme patterns of experimental hepatomas of rats.
Bystander killing of tumour cells by antibody-targeted enzymatic activation of a glucuronide prodrug.
Cure of malignant ascites and generation of protective immunity by monoclonal antibody-targeted activation of a glucuronide prodrug in rats.
Glucuronide transport across the endoplasmic reticulum membrane is inhibited by epigallocatechin gallate and other green tea polyphenols.
Hepatic drug-metabolizing enzymes in primary and secondary tumors of human liver.
Involvement of AP-2 binding sites in regulation of human beta-glucuronidase.
Phosphorylation of beta-glucuronidases from human normal liver and hepatoma by cAMP-dependent protein kinase.
Poly(ethylene glycol) modification of beta-glucuronidase-antibody conjugates for solid-tumor therapy by targeted activation of glucuronide prodrugs.
Potentiation of antitumor immunity by antibody-directed enzyme prodrug therapy.
Regulation of human beta-glucuronidase by A23187 and thapsigargin in the hepatoma cell line HepG2.
Serum activities of lysosomal enzymes in patients with liver cell carcinoma.
Serum and host liver activities of glycosidases and sialyltransferases in animals bearing transplantable tumors.
Serum immunoreactive beta-glucuronidase determined by an enzyme-linked immunosorbent assay in patients with hepatic diseases.
Some properties of beta-glucuronidase activity in normal rat liver and in several transplantable rat hepatomas.
The beta-glucuronidase activity of chemically induced rat hepatoma.
Verapamil regulates activity and mRNA-expression of human beta-glucuronidase in HepG2 cells.
[Cancer-associated alterations of human hepatocellular carcinoma beta-glucuronidase--study on phosphorylation by 3', 5'-cyclic AMP dependent-protein kinase]
[Measurement of serum immunoreactive beta-glucuronidase: a possible serological marker for histological hepatic cell necrosis and to predict the histological progression of hepatitis]
Carcinoma, Large Cell
[beta-Glucuronidase in human maxillary sinus and lung cancers: elevation of activity level and appearance of phosphorylated variant forms]
Carcinoma, Renal Cell
Urinary beta-glucuronidase in renal cell carcinoma.
Urinary beta-glucuronidase in screening and followup of primary urinary tract malignancy.
[The biological characteristics of beta glucuronidase cDNA transfected renal cancer cell line GRC 1/betaG]
Carcinoma, Squamous Cell
Cancer-associated alteration of beta-glucuronidase in human lung cancer: elevated activity and increased phosphorylation.
[beta-Glucuronidase in human maxillary sinus and lung cancers: elevation of activity level and appearance of phosphorylated variant forms]
Carcinoma, Transitional Cell
Comparison of enzyme phenotypes in human bladder tumours and experimentally induced hyperplastic and neoplastic lesions of the rat urinary bladder. A combined histochemical and immunohistochemical approach.
Cardiotoxicity
Enhanced uptake of doxorubicin into bronchial carcinoma: beta-glucuronidase mediates release of doxorubicin from a glucuronide prodrug (HMR 1826) at the tumor site.
Cataract
Variation in glycosidase activity in soluble fractions in ICR/f rat lenses with the progression of cataract formation.
Central Nervous System Neoplasms
[The cerebrospinal fluid concentrations of beta-glucuronidase and beta 2-microglobulin in neurological disorders]
Chediak-Higashi Syndrome
Improvement of Chediak-Higashi leukocyte function by cyclic guanosine monophosphate.
Cholangiocarcinoma
[Cathepsin B-like substance in the monitoring of chemically induced primary cholangiocarcinoma in swine]
Cholangitis
Unconjugated bilirubin in hepatic bile with brown pigment gallstones and cholangitis.
Cholecystitis
Gallbladder epithelial acid hydrolases in human cholecystitis.
The role of prostanoids in the production of acute acalculous cholecystitis by platelet-activating factor.
Choledocholithiasis
Changes of bile duct mucosa after choledochoduodenostomy in rats.
Lipopolysaccharides and beta-glucuronidase activity in choledochal bile in relation to choledocholithiasis.
Cholelithiasis
A large-scale purification of beta-glucuronidase from human liver by immunoaffinity chromatography.
A study of the relationship between beta-glucuronidase and cholelithiasis. I: Activity in bile and the biliary tree.
A study of the relationship between beta-glucuronidase and cholelithiasis. II: Activity of E. coli and their OK antigen serotypes.
Beta-glucuronidase activity related to bacterial growth in common bile duct bile in gallstone patients.
Cholelithiasis in Taiwan. Gallstone characteristics, surgical incidence, bile lipid composition, and role of beta-glucuronidase.
Development and optimization of an enzyme-linked immunosorbent assay employing two murine monoclonal antibodies for absolute quantitation of human beta-glucuronidase.
Human beta-glucuronidase. Studies on the effects of pH and bile acids in regard to its role in the pathogenesis of cholelithiasis.
Human biliary beta-glucuronidase: correlation of its activity with deconjugation of bilirubin in the bile.
Rapid purification of beta-glucuronidase from human liver by immunoaffinity chromatography employing specific murine monoclonal IgG binding to tresyl-activated agarose.
[Beta-glucuronidase activity in bile in cholelithiasis with special reference to anaerobes]
[Changes in bile composition in rabbits infected with Clonorchis sinensis]
Cholera
A TAT-modified fusion protein efficiently penetrates mouse hypoglossal nuclei from transduced ependyma.
Effects of cholera toxin on cyclic AMP accumulation and bone resorption in cultured mouse calvaria.
Identification of receptor regulatory proteins, membrane glycoproteins, and functional characteristics of adenylate cyclase in vesicles derived from the human neutrophil.
Cholestasis
Hepatic and renal beta-glucuronidase activity during extra-hepatic cholestasis.
Human biliary beta-glucuronidase activity before and after relief of bile duct obstruction: is it the major role in the formation of pigment gallstones?
Lysosomal enzymes, alkaline phosphatase, and bilirubin in plasma after bile duct transection in the rat.
Multiplicity and specificity of UDP-glucuronyl transferase. II. Influence of phenobarbital and cholestasis on the activity of glucuronyl transferase and beta-glucuronidase in rat liver.
Radiolabelled colloid uptake distribution and pulmonary contents and localization of lysosomal enzymes in cholestatic rats.
Chondroma
Enzyme histochemical study on bone tumors.
Chondrosarcoma
Enzyme histochemical study on bone tumors.
Chronic Periodontitis
Analysis of human gingival tissue and gingival crevicular fluid beta-glucuronidase activity in specific periodontal diseases.
Comparative analysis of GCF beta-glucuronidase level in diabetic and nondiabetic patients with chronic periodontitis: A clinicobiochemical study.
Enzyme activity in crevicular fluid for detection and prediction of clinical attachment loss in patients with chronic adult periodontitis. Six month results.
Host mediators in gingival crevicular fluid: implications for the pathogenesis of periodontal disease.
The relationship of beta-glucuronidase activity in crevicular fluid to clinical parameters of periodontal disease. Findings from a multicenter study.
The relationship of beta-glucuronidase activity in crevicular fluid to probing attachment loss in patients with adult periodontitis. Findings from a multicenter study.
Within-mouth correlations for indicators of the host response in gingival crevicular fluid.
Ciliary Motility Disorders
Further studies on lymphocyte beta-glucuronidase abnormality in cystic fibrosis. Possible relations to carboxypeptidase B-like activity.
Cleft Palate
Genetic differences among the A/J X C57BL/6J recombinant inbred mouse lines and their degree of association with glucocorticoid-induced cleft palate.
Genetics of glucocorticoid receptor levels in recombinant inbred lines of mice.
Clonorchiasis
[Changes in bile composition in rabbits infected with Clonorchis sinensis]
Colitis
In vitro evaluation of dexamethasone-beta-D-glucuronide for colon-specific drug delivery.
Colitis, Ulcerative
beta-Glucuronidase antibodies in ulcerative colitis.
Impaired inactivation of digestive proteases by deconjugated bilirubin: the possible mechanism for inflammatory bowel disease.
Colonic Neoplasms
Application of microalgal fucoxanthin for the reduction of colon cancer risk: inhibitory activity of fucoxanthin against beta-glucuronidase and DLD-1 cancer cells.
Biliary control of beta-glucuronidase activity in the luminal contents of the rat ileum, cecum, and rectum.
Calcium-D-glucarate.
Effect of coconut cake on the bacterial enzyme activity in 1,2-dimethyl hydrazine induced colon cancer.
Effect of dietary fiber on colonic bacterial enzymes and bile acids in relation to colon cancer.
Effect of ginger on bacterial enzymes in 1,2-dimethylhydrazine induced experimental colon carcinogenesis.
Fecal sterols and bacterial beta-glucuronidase activity: a preliminary metabolic epidemiology study of healthy volunteers from Umea, Sweden, and metropolitan New York.
Flaxseed and lignans increase cecal beta-glucuronidase activity in rats.
Gene expression imaging by enzymatic catalysis of a fluorescent probe via membrane-anchored beta-glucuronidase.
Influence of diet and age on fecal bacterial enzymes.
Intestinal bacterial beta-glucuronidase activity of patients with colon cancer.
Invited review: Bovine milk fat globule membrane as a potential nutraceutical.
Protective role of luteolin in 1,2-dimethylhydrazine induced experimental colon carcinogenesis.
Reduction of beta-glucuronidase and nitroreductase activity by yoghurt in a murine colon cancer model.
Silymarin and its components are inhibitors of beta-glucuronidase.
Synthesis and Antitumor Properties of BQC-Glucuronide, a Camptothecin Prodrug for Selective Tumor Activation.
The cytochemical demonstration of beta-glucuronidase in colon neoplasms of rats exposed to azoxymethane.
The influence of flaxseed and lignans on colon carcinogenesis and beta-glucuronidase activity.
The influence of Lactobacillus rhamnosus LC705 together with Propionibacterium freudenreichii ssp. shermanii JS on potentially carcinogenic bacterial activity in human colon.
[New means for the prophylaxis of colon cancer with the use of beta-glucuronidase inhibitors]
Colorectal Neoplasms
Characterization of beta-glucosidase and beta-glucuronidase of alkalotolerant intestinal bacteria.
Distribution and gene mutation of enteric flora carrying ?-glucuronidase among patients with colorectal cancer.
Effect of dietary fiber on the induction of colorectal tumors and fecal beta-glucuronidase activity in the rat.
Effects of high- and low-risk diets on gut microflora-associated biomarkers of colon cancer in human flora-associated rats.
Hepatic drug-metabolizing enzymes in primary and secondary tumors of human liver.
Relationship of beta-glucuronidase to differentiation and invasion of human colorectal carcinoma.
The in vitro metabolism of irinotecan (CPT-11) by carboxylesterase and beta-glucuronidase in human colorectal tumours.
The mannose 6-phosphate/insulin-like growth factor-II receptor is a substrate of type V transforming growth factor-beta receptor.
The relative contributions of carboxylesterase and beta-glucuronidase in the formation of SN-38 in human colorectal tumours.
Cone Dystrophy
Progressive cone dystrophy associated with low alpha-L-fucosidase activity in serum and leukocytes.
Congenital Abnormalities
Beta-glucuronidase deficiency in a girl with unusual clinical features.
Delayed developmental sequences in rodent diabetic embryopathy.
Coronary Artery Disease
Increased activity of serum beta-glucuronidase in patients with coronary artery disease.
[Identification of endogenous control genes for gene expression studies in peripheral blood of patients with coronary artery disease].
[Study of blood beta-glucuronidase activity in young persons with coronary arteriosclerosis]
Crohn Disease
Bacterial enzymes used for colon-specific drug delivery are decreased in active Crohn's disease.
Cystic Fibrosis
A sensitive, real-time, RNA-specific PCR method for the detection of recombinant AAV-CFTR vector expression.
Abnormal beta-glucuronidase activity in cystic fibrosis.
Abnormal response of cultured lymphocytes to phytohemagglutinin and autologous serum in cystic fibrosis.
Acid hydrolases in sera and plasma from patients with cystic fibrosis.
Alteration of the N-formyl-methionyl-leucyl-phenylalanine-induced response in cystic fibrosis neutrophils.
Analysis of granulocyte beta-adrenergic response in cystic fibrosis: correlation of decreased responsiveness with disease severity.
Demonstration of human leukocyte degranulation induced by sera from homozygotes and heterozygotes for cystic fibrosis.
Further studies on lymphocyte beta-glucuronidase abnormality in cystic fibrosis. Possible relations to carboxypeptidase B-like activity.
Interstitial 7q deletion [46,XX,del(7)(pter----q21.1::q22----qter)] and the location of genes for beta-glucuronidase and cystic fibrosis.
Quantitative determination of beta-glucuronidase in sweat gland and other skin components in cystic fibrosis.
Studies in meconium in cystic fibrosis: the activities of alpha-D-mannosidase, beta-glucuronidase, beta-D-fucosidase, acid and alkaline phosphatase.
[Determination of beta-glucuronidase activity in fibroblast cultures from children with mucoviscidosis]
[Proceedings: Study of beta-glucuronidase in lymphocytes cultivated in vitro in cystic fibrosis]
Cystinosis
A study of the low beta-galactosidase activity in cystinotic fibroblasts: effects of cysteamine.
Activities of acid hydrolases in fibroblasts from normal and cystinotic children.
Cysts
beta-Glucuronidase levels in patients with fibrocystic breast disease.
Myo-inositol oxygenase genes are involved in the development of syncytia induced by Heterodera schachtii in Arabidopsis roots.
Regulatory sequences of Arabidopsis drive reporter gene expression in nematode feeding structures.
The promoter of the Arabidopsis thaliana Cel1 endo-1,4-beta glucanase gene is differentially expressed in plant feeding cells induced by root-knot and cyst nematodes.
Dehydration
An Arabidopsis myb homolog is induced by dehydration stress and its gene product binds to the conserved MYB recognition sequence.
Networking senescence-regulating pathways by using Arabidopsis enhancer trap lines.
Organization and expression of two Arabidopsis DREB2 genes encoding DRE-binding proteins involved in dehydration- and high-salinity-responsive gene expression.
Dental Caries
beta-Glucuronidase inhibitor-activity in human saliva and its relation to dental caries, secretor status and blood group.
Dental Deposits
[Enzymatic protective systems of saliva in inflammation of the periodontium]
Dental Plaque
Impact of Smoking on Neutrophil Enzyme Levels in Gingivitis: A Case-Control Study.
Dermatitis, Atopic
Atopic dermatitis: influence of bacterial infections on human monocyte and neutrophil granulocyte functional activities.
Decreased release of lysosomal enzymes from peripheral leukocytes of patients with atopic dermatitis.
Fc receptors for IgE and interleukin-4 induced IgE and IgG4 secretion.
IgG-, IgA-, and IgE-induced release of leukotriene C4 by monocytes isolated from patients with atopic dermatitis.
Impaired H2 histamine granulocyte response in active atopic eczema.
Diabetes Insipidus
[Study on beta-glucuronidase activity in infants. 2. Effect of vasopressin on urinary beta-glucuronidase in nephrogenic diabetes insipidus]
Diabetes Insipidus, Nephrogenic
Response of urinary beta-glucuronidase excretion to vasopressin with a possible abnormality in congenital nephrogenic diabetes insipidus.
[Study on beta-glucuronidase activity in infants. 2. Effect of vasopressin on urinary beta-glucuronidase in nephrogenic diabetes insipidus]
Diabetes Mellitus
Alterations in the activity of several glycohydrolases in red blood cell membrane from type 2 diabetes mellitus patients.
Beta-glucuronidase in lymphocytes of patients with diabetes mellitus.
Evidence of polymorphonuclear neutrophils (PMN) activation in patients with insulin-dependent diabetes mellitus.
Increase of serum beta-glucuronidase activity in human diabetes mellitus.
Serum beta-glucuronidase activity in human diabetes mellitus, granuloma annulare and necrobiosis lipoidica.
The deficiency of B-glycosidases in leukocytes from patients with non-insulin dependent diabetes mellitus.
The influence of diabetes on gingival crevicular fluid beta-glucuronidase and interleukin-8.
Urinary excretion of beta-glucuronidase, N-acetyl-beta-D-glucosaminidase, alpha-glucosidase and trehalase in diabetes mellitus.
[Beta-glucuronidase deficiency in the peripheral neutrophils in diabetes mellitus]
[Beta-glucuronidase in lymphocytes of patients with diabetes mellitus complicated by infections]
[Beta-glucuronidase in lymphocytes of patients with diabetes mellitus]
[Beta-glucuronidase of peripheral blood lymphocytes of patients with diabetes mellitus in relation to pharmacological treatment]
[Diagnostic evidence of serum beta-glucuronidase. IV. Serum beta glucuronidase activity in arteriosclerosis and diabetes mellitus]
[Serum beta-glucuronidase activity in diabetes mellitus as influenced by sex and age]
[Urinary enzymes as a marker of the preclinical stage of diabetic nephropathy]
Diabetes Mellitus, Experimental
[Beta-glucuronidase activity in serum, liver and kidney tissue in alloxan diabetes]
Diabetes Mellitus, Type 1
Urinary beta-glucuronidase excretion in insulin-dependent diabetes mellitus: relation with diabetic nephropathy.
Diabetes Mellitus, Type 2
Alterations in the activity of several glycohydrolases in red blood cell membrane from type 2 diabetes mellitus patients.
The influence of diabetes on gingival crevicular fluid beta-glucuronidase and interleukin-8.
Diabetes, Gestational
Serum beta-glucuronidase activity during pregnancy in gestational diabetes.
Diabetic Nephropathies
Urinary activity of beta-glucuronidase and excretion of glycosaminoglycans in the diagnosis of diabetic nephropathy.
Urinary beta-glucuronidase excretion in insulin-dependent diabetes mellitus: relation with diabetic nephropathy.
[Urinary enzymes as a marker of the preclinical stage of diabetic nephropathy]
Diabetic Retinopathy
Lysosomal enzymes in tear fluids from patients with ocular diseases.
Diphtheria
A Brassica S-locus gene promoter targets toxic gene expression and cell death to the pistil and pollen of transgenic Nicotiana.
Pollen-specific expression of the Arabidopsis thaliana alpha 1-tubulin promoter assayed by beta-glucuronidase, chloramphenicol acetyltransferase and diphtheria toxin reporter genes.
[Modification of beta-glucuronidase, leucine aminopeptidase and alkaline phosphatase activities by diphtheria toxin in experimental animals]
Distemper
Beta-glucuronidase activity, and levels of protein and protein fractions in serum and cerebrospinal fluid of dogs with distemper associated demyelinating encephalopathy.
Enzyme activities associated with the demyelinating phase of canine distemper. I. Beta-glucuronidase, acid and neutral proteinases.
Diverticulum
Beta-glucuronidase activity in the bile of gallstone patients both with and without duodenal diverticula.
beta-Glucuronidase in common duct bile, methodological aspects, variation of pH optima and relation to gallstones.
Lipopolysaccharides and beta-glucuronidase activity in choledochal bile in relation to choledocholithiasis.
Duodenal Ulcer
beta-Glucuronidase in gastric aspirate after oral cimetidine in the diagnosis of carcinoma of the stomach.
Effect of ayurvedic medicines on beta-glucuronidase activity of Brunner's glands during recovery from cysteamine induced duodenal ulcers in rats.
Dysentery, Amebic
Role of beta-glucuronidase, a lysosomal enzyme, in the pathogenesis of intestinal amoebiasis: an experimental study.
Dystonic Disorders
Elevated beta-N-acetylhexosaminidase activity in focal dystonia fibroblasts.
Empyema
Usefulness of monitoring beta-glucuronidase in pleural effusions.
Encephalitis
Brain lysosomal glycosidase activity in immunosuppressed mice infected with avirulent Semliki forest virus.
Encephalomyelitis, Autoimmune, Experimental
Cerebrospinal fluid beta-glucuronidase activity in rabbits with experimental allergic encephalomyelitis.
Lysosomal enzymes in experimental allergic encephalomyelitis: time course and evidence of the source.
Endocrine System Diseases
[ESTIMATION OF THE SERUM BETA-GLUCURONIDASE ACTIVITY DURING HEPATIC PARENCHYMATOUS DISEASE AND CERTAIN ENDOCRINE DISEASES.]
Endometriosis
Enzymatic deficiencies of the immune system cells in patients with cancer of the larynx and other malignancies.
Endotoxemia
Equine Escherichia coli endotoxemia: comparison of intravenous and intraperitoneal endotoxin administration.
Role of intestinal barrier in pathogenesis of pigment gallstone in a guinea pig model.
[Relationship between pigment gallstone and intestinal barrier function: experiment with guinea pigs and clinical observations]
Epilepsy
Elevation of beta-glucuronidase activity in medicated patients with epilepsy.
[Serum beta-glucuronidase activity in patients with epilepsy]
Essential Hypertension
[Estimation of the urinary aldosterone (author's transl)]
Fabry Disease
Lysosomal leukocyte beta-D-glucuronidase during enzyme replacement therapy in Fabry disease.
Middelheim Fabry Study (MiFaS): a retrospective Belgian study on the prevalence of Fabry disease in young patients with cryptogenic stroke.
The ratio of alpha-galactosidase to beta-glucuronidase activities in dried blood for the identification of female Fabry disease patients.
Fanconi Syndrome
Coordinately increased lysozymuria and lysosomal enzymuria induced by maleic acid.
Fascioliasis
Studies on serum beta-glucuronidase activity and urinary tryptophan metabolites in human fascioliasis.
Fatty Liver
[Diagnosis of fatty degeneration of the liver and fatty liver with special consideration of serum beta-glucuronidase activity]
Favism
[Erythrocyte antioxidant enzymatic systems and serum beta-glucuronidase in subjects with favism. Preliminary results]
Fetal Death
beta-Glucuronidase deficiency as a cause of fetal hydrops.
Fetal Hypoxia
[Beta-glucuronidase activity in the amniotic fluid, cord blood and maternal blood serum in the course of normal deliveries and those complicated by fetal hypoxia]
Fibrocystic Breast Disease
beta-Glucuronidase levels in patients with fibrocystic breast disease.
Fibroma
Enzyme histochemical study on bone tumors.
Fibromatosis, Gingival
Acid phosphatase and beta-glucuronidase activities in mast cells, macrophages, plasma cells and lymphocytes in gingival fibromatosis.
Fibrosarcoma
Piroxicam, indomethacin and aspirin action on a murine fibrosarcoma. Effects on tumour-associated and peritoneal macrophages.
Foodborne Diseases
Investigating the role of small, acid-soluble spore proteins (SASPs) in the resistance of Clostridium perfringens spores to heat.
Foot-and-Mouth Disease
Foot-and-mouth disease virus 2A oligopeptide mediated cleavage of an artificial polyprotein.
The 'cleavage' activities of foot-and-mouth disease virus 2A site-directed mutants and naturally occurring '2A-like' sequences.
Gallstones
Bacteria and gallstone nucleation.
Beta-glucuronidase activity in the bile of gallstone patients both with and without duodenal diverticula.
Beta-glucuronidase activity related to bacterial growth in common bile duct bile in gallstone patients.
beta-Glucuronidase in common duct bile, methodological aspects, variation of pH optima and relation to gallstones.
Biliary bacterial factors determine the path of gallstone formation.
Biliary D-glucaric acid: its quantitation and preventive role in gallstone formation.
Biliary electrolytes and enzymes in patients with and without gallstones.
Cholelithiasis in Taiwan. Gallstone characteristics, surgical incidence, bile lipid composition, and role of beta-glucuronidase.
D-glucaro-1,4-lactone: its excretion in the bile and urine and effect on the biliary secretion of beta-glucuronidase after oral administration in rats.
Deconjugation of bilirubin accelerates coprecipitation of cholesterol, fatty acids, and mucin in human bile--in vitro study.
Effects of choleretics on bile compositions drained from patients with pigment gallstone.
Effects of diet on glucaric acid concentration in bile and the formation of calcium bilirubinate gallstones.
Effects of pH on the deconjugation of conjugated bilirubin in human bile.
Human biliary beta-glucuronidase activity before and after relief of bile duct obstruction: is it the major role in the formation of pigment gallstones?
Inhibition of cholesterol crystallization under bilirubin deconjugation: partial characterization of mechanisms whereby infected bile accelerates pigment stone formation.
Juxtapapillary duodenal diverticula.
Nonbacterial transformation of bilirubin in bile.
Pathogenesis of calcium bilirubinate gallstone: role of E. coli, beta-glucuronidase and coagulation by inorganic ions, polyelectrolytes and agitation.
Pigment gallstone pathogenesis: slime production by biliary bacteria is more important than beta-glucuronidase production.
Role of intestinal barrier in pathogenesis of pigment gallstone in a guinea pig model.
The pathophysiological characteristics of bile from patients with gallstones: the role of prostaglandins and mucin in gallstone formation.
The preliminary experimental and clinical study of the relationship between the pigment gallstone and intestinal mucosal barrier.
[Clinical and experimental observations of jinqiancao gao on preventive and therapeutic effects in cholelithiasis]
[Clinical and experimental studies on the formation of calcium bilirubinate gallstones]
[Experimental gallstone formation. Etiological significance of beta-glucuronidase producing bacteria and biliary obstruction]
[Relationship between pigment gallstone and intestinal barrier function: experiment with guinea pigs and clinical observations]
[The changes of beta-glucuronidase in rabbit model with calcium bilirubinate stone]
Gangliosidosis, GM1
Selective noncompetitive assimilation of bovine testicular beta-galactosidase and bovine liver beta-glucuronidase by generalized gangliosidosis fibroblasts.
Gastritis
Beta-glucuronidase, gastritis, and gastric carcinoma.
Gaucher Disease
Acid hydrolases in serum from patients with lysosomal disorders.
[Roentgenologic characteristics of Gaucher's disease (author's transl)]
Genetic Diseases, Inborn
Herpesvirus vector gene transfer and expression of beta-glucuronidase in the central nervous system of MPS VII mice.
Genital Diseases, Female
[Enzyme levels and carcinoma treatment. 1. The serum beta-glucuronidase activity in patients with malignant gynecologic diseases before, during and after the clinical treatment]
Giant Cell Tumors
Enzyme histochemical study on bone tumors.
Gingivitis
Development of a biochemical profile for gingival crevicular fluid. Methodological considerations and evaluation of collagen-degrading and ground substance-degrading enzyme activity during experimental gingivitis.
Impact of Smoking on Neutrophil Enzyme Levels in Gingivitis: A Case-Control Study.
Lactate dehydrogenase, beta-glucuronidase and arylsulfatase activity in gingival crevicular fluid associated with experimental gingivitis in man.
Secretory function of neutrophilic leukocytes of the patients with periodontal diseases.
Glioblastoma
Increased activity of lysosomal glycohydrolases in glioma tissue and surrounding areas from human brain.
Glioma
An investigation in vitro of the exocytosis of lysosomal enzymes from C6 glioma cells.
Direct transfer of beta-glucuronidase from mouse macrophages to other types of cell.
Localizations of beta-glucuronidase activity in sections and cultures of human gliomas.
Lysosomal isozyme patterns in ethylnitrosourea-induced brain tumors.
Receptor-mediated uptake of beta-glucuronidase into primary astrocytes and C6 glioma cells from rat brain.
[Histochemical demonstration of glial enzyme activity. II. Reagent and neoplastic glia]
Glomerulonephritis
Acid mucopolysaccharide and one of its glomerular degrading enzymes beta-glucuronidase in experimental and human glomerulonephritis.
beta-Glucuronidase in experimental chronic glomerulonephritis.
Involvement of the macrophage in experimental chronic immune complex glomerulonephritis.
Glucose Metabolism Disorders
Serum beta-glucuronidase activity in diabetic patients as related to vascular complications and degree of glucose metabolic disorder.
glucuronosyltransferase deficiency
UDP-glucuronyltransferase-catalyzed deconjugation of bilirubin monoglucuronide.
glutathione peroxidase deficiency
Increased sensitivity to H2O2 in glutathione peroxidase-deficient rat granulocytes.
Granuloma
Histochemical analysis of experimental granulomatous uveitis.
Histoenzymology of the lung. II. The behaviour of lung hydrolytic enzymes during some experimental pulmonary processes.
Influence of hypercholesterolemia and cholesterol accumulation on rabbit carrageenan granuloma macrophage activation.
Management of inflammation: proamidase as a parameter for a better understanding of inflammatory processes.
Streptozotocin diabetes: prolonged inflammatory response with delay in granuloma formation.
Granuloma Annulare
Serum beta-glucuronidase activity in human diabetes mellitus, granuloma annulare and necrobiosis lipoidica.
Granulomatous Disease, Chronic
Oxidative damage to lysosomal enzymes in human phagocytosing neutrophils.
Phagocytosing human neutrophils inactivate their own granular enzymes.
Graves Disease
Serum lysosomal acid hydrolase activities in Graves' disease.
Hemostatic Disorders
Liver damage induced in rats by malathion impurities.
Hepatitis
BETA-GLUCURONIDASE AND ACID PHOSPHATASE ACTIVITIES OF LYSOSOMAL PREPARATIONS FROM HUMAN LIVER TISSUE OBTAINED BY NEEDLE BIOPSY FROM SUBJECTS WITH ACUTE HEPATITIS AND CIRRHOSIS.
Diethyldithiocarbamate inhibition of galactosamine-induced hepatitis in rats.
Release of beta-glucuronidase as a quantitative assay of murine viral hepatitis injury in cultured cells.
Rifampicin, halothane and glucose as mediators of lysosomal enzyme release and tissue damage.
Serum alkaline-stable acid thiol proteinase--a possible marker for primary liver carcinoma.
Serum and urinary beta-glucuronidase activity in viral hepatitis and obstructive jaundice cases.
Serum immunoreactive beta-glucuronidase determined by an enzyme-linked immunosorbent assay in patients with hepatic diseases.
The behavior of aspartic and alanine aminotransferases, lactic dehydrogenase, cholinesterase, prothrombin, beta-glucuronidase, bilirubin, thymol turbidity test and serum proteinograms under the influence of corticotherapy in the course of viral hepatitis in children.
[Activity of lysosomal enzymes acid phosphatase and beta-glucuronidase in patients with viral hepatitis]
[Comparative determinations of beta-glucuronidase and aminotransferases in the serum of patients with viral hepatitis]
[Measurement of serum immunoreactive beta-glucuronidase: a possible serological marker for histological hepatic cell necrosis and to predict the histological progression of hepatitis]
[Serum beta-glucuronidase activity in viral hepatitis as related to its therapeutic management]
[Serum beta-glucuronidase and leucine aminopeptidase in the diagnosis of hepatitis and cirrhosis.]
[Serum beta-glucuronidase in viral hepatitis]
[Studies on beta-glucuronidase. II. Clinical application of the assay method of beta-glucuronidase activity using p-nitrophenylglucuronide as the substrate. III. The significance of the serum beta-glucuronidase activity in patients with liver diseases, with special references to its relation with the serum transaminase activity, and to its characteristic behavior in cholangiolitic hepatitis.]
[The significance of E and EAC rosettes, acid phosphatase and beta-glucuronidase activity in lymphocyte rosettes, and the level of glycogen in peripheral blood leukocytes in patients with viral hepatitis]
Hepatitis B
Expression of genes involved in lipogenesis is not increased in patients with HCV genotype 3 in human liver.
Hepatitis, Chronic
Serum immunoreactive beta-glucuronidase determined by an enzyme-linked immunosorbent assay in patients with hepatic diseases.
[Activity of serum beta-glucuronidase in liver cirrhosis and chronic hepatitis]
[BETA-GLUCURONIDASE ACTIVITY IN SOME FORMS OF CHRONIC HEPATITIS.]
[Measurement of serum immunoreactive beta-glucuronidase: a possible serological marker for histological hepatic cell necrosis and to predict the histological progression of hepatitis]
Herpes Simplex
An HSV-1 containing the rat beta-glucuronidase cDNA inserted within the LAT gene is less efficient than the parental strain at establishing a transcriptionally active state during latency in neurons.
Herpes simplex virus type 2 UL24 gene is a virulence determinant in murine and guinea pig disease models.
Long-term AAV vector gene and protein expression in mouse brain from a small pan-cellular promoter is similar to neural cell promoters.
Regulation of transgene expression in plants with polydactyl zinc finger transcription factors.
Significantly increased expression of beta-glucuronidase in the central nervous system of mucopolysaccharidosis type VII mice from the latency-associated transcript promoter in a nonpathogenic herpes simplex virus type 1 vector.
Widespread correction of lysosomal storage in the mucopolysaccharidosis type VII mouse brain with a herpes simplex virus type 1 vector expressing beta-glucuronidase.
Herpes Zoster
Effects of culture conditions on the developmental programme of mouse blastocysts.
Stereological and biochemical investigations on a possible aldosterone-containing secretory organelle in the zona glomerulosa of rat adrenal gland.
Ultrastructure of opossum oocyte investing coats and their sensitivity to trypsin and hyaluronidase.
Histiocytoma, Malignant Fibrous
Enzyme histochemical study on bone tumors.
HIV Infections
A novel lectin from Pseudostellaria heterophylla roots with sequence simularity to Kunitz-type soybean trypsin inhibitor.
Epidemiology and diagnosis of HIV-associated periodontal diseases.
Structurally dissimilar proteins with antiviral and antifungal potency from cowpea (Vigna unguiculata) seeds.
Hodgkin Disease
Beta-glucuronidase activity of lymph node imprints from malignant lymphomas and chronic lymphocytic leukaemia.
Beta-glucuronidase activity of the white blood cells in human leukemias and Hodgkin's disease.
[Blastogenesis and activation of beta-glucuronidase in cultured lymphocytes from children with Hodgkin's disease and their blood relatives. Possible interference of genetic factors in the etiopathogenesis of the disease]
Huntington Disease
Changes in nine enzyme markers for neurons, glia, and endothelial cells in agonal state and Huntington's disease caudate nucleus.
Hydatidiform Mole
beta-Glucuronidase and oestrogens in hydatidiform mole.
Studies of beta-glucuronidase in first-trimester placenta, term placenta and hydatidiform mole.
Hydrops Fetalis
beta-Glucuronidase deficiency as a cause of fetal hydrops.
Beta-glucuronidase deficiency as a cause of prenatally diagnosed non-immune hydrops fetalis.
Beta-glucuronidase deficiency as cause of recurrent hydrops fetalis: the first early prenatal diagnosis by chorionic villus sampling.
Incidence of the mucopolysaccharidoses in Northern Ireland.
Intracisternal A-particle element transposition into the murine beta-glucuronidase gene correlates with loss of enzyme activity: a new model for beta-glucuronidase deficiency in the C3H mouse.
Lysosomal storage diseases presenting as transient or persistent hydrops fetalis.
Molecular analysis of a patient with hydrops fetalis caused by beta-glucuronidase deficiency, and evidence for additional pseudogenes.
Molecular analysis of patients with beta-glucuronidase deficiency presenting as hydrops fetalis or as early mucopolysaccharidosis VII.
Mucopolysaccharidosis VII as cause of fetal hydrops in early pregnancy.
Non-immune hydrops fetalis caused by beta-glucuronidase deficiency (mucopolysaccharidosis VII). Study of a family with 3 affected siblings.
Postmortem observations on beta-glucuronidase deficiency presenting as hydrops fetalis.
Hyperbilirubinemia, Neonatal
Beta-glucuronidase and hyperbilirubinemia in breast-fed versus formula-fed babies.
Hypercholesterolemia
Acid and neutral lipase activity in lymphocytes of patients with increased serum cholesterol and triglyceride level.
Influence of hypercholesterolemia and cholesterol accumulation on rabbit carrageenan granuloma macrophage activation.
Hyperglycemia
Physiology of the potentiation of lethal endotoxin shock by streptococcal pyrogenic exotoxin in rabbits.
Plasma glycohydrolase levels in patients with type 1 diabetes at onset and in subjects undergoing an intravenous glucose tolerance test.
Tumor-targeted delivery of 8-hydroxyquinoline.
Hyperoxaluria
Renal peroxidative changes mediated by oxalate: the protective role of fucoidan.
Hypersensitivity
A double-blind randomized placebo-controlled trial with short-term beta-glucuronidase therapy in children with chronic rhinoconjunctivitis and/or asthma due to dust mite allergy.
Androgen responsiveness of the murine beta-glucuronidase gene is associated with nuclease hypersensitivity, protein binding, and haplotype-specific sequence diversity within intron 9.
[Beta-glucuronidase in nasal secretions of patients with nasal allergy]
[Effects of iodine-enriched egg (IE-egg) on nasal allergy: basic and clinical investigations]
Hypersensitivity, Delayed
Histoenzymology of the lung. II. The behaviour of lung hydrolytic enzymes during some experimental pulmonary processes.
Hypertension
A lack of coordination in the release of urinary lysosomal and brush border enzymes following renovascular surgery.
Evaluation of urinary enzyme patterns in patients with kidney diseases and primary benign hypertension.
Increased serum glycosidase activity in human hypertension.
Proceedings: Suppression of the development of hypertension by N, N'-2,7-fluorenilene-bisacetamide and beta-glucuronidase inhibitor in spontaneously hypertensive rats.
[Renal dipeptidylpeptidase IV excretion in drug-induced kidney changes]
Hyperthyroidism
Activities of UDP-glucuronyltransferase, beta-glucuronidase and deiodinase types I and II in hyper- and hypothyroid rats.
Serum lysosomal acid hydrolase activities in Graves' disease.
Thyroid hormones and the hepatic handling of bilirubin. I. Effects of hypothyroidism and hyperthyroidism on the hepatic transport of bilirubin mono- and diconjugates in the Wistar rat.
[Cytochemical properties of peripheral blood neutrophils in patients with hyperthyroidism]
[Serum beta-glucuronidase activity in hyperthyroid subjects.]
Hypoglycemia
Physiology of the potentiation of lethal endotoxin shock by streptococcal pyrogenic exotoxin in rabbits.
Protective effects of aspirin in endotoxic shock.
The effects of alpha adrenergic blockade on arachidonic acid metabolism and shock sequelae in endotoxemia.
Hypoproteinemia
Comparative responses of genetically resistant and nonselected Japanese quail to dietary aflatoxin.
Hypothyroidism
Activities of UDP-glucuronyltransferase, beta-glucuronidase and deiodinase types I and II in hyper- and hypothyroid rats.
[Cytochemical examination of peripheral blood neutrophils of patients with hypothyroidism]
Hypoxia, Brain
[Changes in beta-glucuronidase activity in arterial and jugular vein blood, and in cerebrospinal fluid in the rabbit after cerebral anoxia induced by clamping]
Infections
A plant gene up-regulated at rust infection sites.
A study on the etiological factors of bilharzial bladder cancer in Egypt. 6. The possible role of urinary bacteria.
Acid mucopolysaccharide metabolism in leprosy. 3. Hyaluronic acid mycobacterial growth enhancement, and growth suppression by saccharic acid and vitamin C as inhibitors of beta-glucuronidase.
An experimental study on the effect of praziquantel and oltipraz on some lysosomal enzymes.
Analysis of a new begomovirus unveils a composite element conserved in the CP gene promoters of several Geminiviridae genera: Clues to comprehend the complex regulation of late genes.
Assessment of beta-glucuronidase levels in goat's milk as an indicator of mastitis: comparison with other mastitis detection methods.
Atopic dermatitis: influence of bacterial infections on human monocyte and neutrophil granulocyte functional activities.
Beta-D-Glucuronidase activity among prototrophic and auxotrophic variants of Escherichia coli and other Enterobacteriaceae commonly implicated in urinary tract infections.
beta-Glucuronidase activity in cerebrospinal fluid pleocytosis due to urinary tract infection.
Beta-glucuronidase deficiency. A heterogeneous mucopolysaccharidosis.
Cell-to-cell transport of movement-defective cucumber mosaic and tobacco mosaic viruses in transgenic plants expressing heterologous movement protein genes.
Characterization of the inflammatory cells in progressing tumor-like alveolar hydatid cyst. 2. Cell surface receptors, endocytosed immune complexes and lysosomal enzyme content.
Comparative development of Brugia pahangi and variation in acid hydrolase enzyme titers in.
Diagnostic potential of urinary enzymes and beta 2-microglobulin in acute urinary tract infection.
Early transcription of Agrobacterium T-DNA genes in tobacco and maize.
Effects of diet on glucaric acid concentration in bile and the formation of calcium bilirubinate gallstones.
Failure of urinary beta-glucuronidase activity to localize the site of urinary tract infection.
Fate of Mycobacterium tuberculosis inside rat peritoneal macrophages in vitro.
Gene silencing by expression of hairpin RNA in Lotus japonicus roots and root nodules.
In vitro regeneration and Agrobacterium-mediated genetic transformation of Euonymus alatus.
Infection of tobacco or Arabidopsis plants by CMV counteracts systemic post-transcriptional silencing of nonviral (trans)genes.
Intron-tagged epitope: a tool for facile detection and purification of proteins expressed in Agrobacterium-transformed plant cells.
Isolation of the promoter of a cotton beta-galactosidase gene (GhGal1) and its expression in transgenic tobacco plants.
Low beta-glucuronidase enzyme activity and mutations in the human beta-glucuronidase gene in mild mucopolysaccharidosis type VII, pseudodeficiency and a heterozygote.
Multiple copies of virG enhance the transient transformation of celery, carrot and rice tissues by Agrobacterium tumefaciens.
Permeability changes of plasma and lysosomal membranes in HeLa cells infected with rabbit poxvirus.
Primary bile duct stones and bacterial activity.
Rapid detection of urinary tract infection caused by Escherichia coli or Proteeae species.
Rapid identification of micro-organisms from urinary tract infections by beta-glucuronidase, phenylalanine deaminase, cytochrome oxidase and indole tests on isolation media.
Regeneration of herbicide-tolerant black locust transgenic plants by SAAT.
Sequential metabolic alterations in the myocardium during influenza and tularemia in mice.
Serum anti-Escherichia coli antibodies and urinary beta-glucuronidase for the diagnosis and control of evolution of urinary infection during pregnancy.
The effect of intracellular Chlamydia psittaci on lysosomal enzyme activities in mouse peritoneal macrophages.
The effect of Schistosoma haematobium infection on the activity of urinary beta-glucuronidase.
The effects of strenuous exercise on infection with Francisella tularensis in rats.
The PsCZF1 gene encoding a C2H2 zinc finger protein is required for growth, development and pathogenesis in Phytophthora sojae.
The value of urinary beta-glucuronidase activity in the assessment of urinary tract infections.
URINARY BETA-GLUCURONIDASE ACTIVITY IN PATIENTS WITH URINARY-TRACT INFECTION.
Use of beta-Glucuronidase activity to quantify the growth of Fusarium oxysporum f. sp. radicis-lycopersici during infection of tomato.
Use of Coniothyrium minitans transformed with the hygromycin B resistance gene to study survival and infection of Sclerotinia sclerotiorum sclerotia in soil.
[Beta-glucuronidase in lymphocytes of patients with diabetes mellitus complicated by infections]
[Lysosomal activity in enterocytes in the small intestine in piglets experimentally infected with Isospora suis]
[Rapid method for identifying Escherichia coli and species of the Proteeae tribe in urine]
[Studies on beta-glucuronidase activities in liver, stomach and small intestinal tissues of rabbits infected with Clonorchis sinensis]
[Study of lysosomal enzymes in chick embryo fibroblasts infected with microorganisms of family Halprowiaceae (Chlamydiaceae)]
[Value of the assay of 4 urinary enzyme activities in the diagnosis of the infectious or toxic (aminoglycosides) origin of a renal disease. Preliminary results]
Infectious Mononucleosis
[Acid phosphatase isoenzyme, beta-glucuronidase and non-specific esterase activity in certain morphological groups of atypical mononuclear cells in circulating blood in infectious mononucleosis]
[Serum beta-glucuronidase in infectious mononucleosis]
Infertility, Male
Efficient production of genetically engineered, male-sterile Arabidopsis thaliana using anther-specific promoters and genes derived from Brassica oleracea and B. rapa.
Inflammatory Bowel Diseases
Beta-glucuronidase and Beta-glucosidase activity in stool specimens of children with inflammatory bowel disease.
Impaired inactivation of digestive proteases by deconjugated bilirubin: the possible mechanism for inflammatory bowel disease.
Influenza, Human
Sequential metabolic alterations in the myocardium during influenza and tularemia in mice.
The potential of Lactobacillus as a carrier for oral immunization: development and preliminary characterization of vector systems for targeted delivery of antigens.
Insulinoma
Glycophase glass revisited: protein adsorption and cell growth on glass surfaces bearing immobilized glycerol monosaccharides.
Overexpression of G11alpha and isoforms of phospholipase C in islet beta-cells reveals a lack of correlation between inositol phosphate accumulation and insulin secretion.
Intellectual Disability
Acid hydrolases in serum from patients with lysosomal disorders.
Beta-glucuronidase deficiency in a girl with unusual clinical features.
Decreased lysosomal storage in the adult MPS VII mouse brain in the vicinity of grafts of retroviral vector-corrected fibroblasts secreting high levels of beta-glucuronidase.
Juvenile neurogenic muscle atrophy with lysosomal enzyme deficiencies: new disease or variant of mucopolysaccharidosis?
Ischemic Stroke
Middelheim Fabry Study (MiFaS): a retrospective Belgian study on the prevalence of Fabry disease in young patients with cryptogenic stroke.
Jaundice, Neonatal
Breast milk beta-glucuronidase and exaggerated jaundice in the early neonatal period.
Breast milk beta-glucuronidase and neonatal jaundice.
Inhibition of beta-glucuronidase by casein hydrolysate formula.
Joint Diseases
Optimization of an enzymatic method for the determination of lysosomal N-acetyl-beta-D-hexosaminidase and beta-glucuronidase in synovial fluid.
[Activity of beta-glucuronidase in the synovial fluid in rheumatoid arthritis and degenerative joint diseases]
[Clinical studies of intra-articular injections of Arteparon. Retrospective study following the treatment of 754 patients]
Keratitis, Herpetic
[Glycosidase activity of the tears in patients with ophthalmic herpes]
[Use of tear enzyme assay to predict recurrent herpetic keratitis in children]
Kidney Diseases
Serum and urinary arginine-esterase activity in paediatric kidney diseases.
[Determination of urinary beta-glucuronidase activity as an expression of renal damage in various forms of kidney diseases in children]
[Estimation of the urinary aldosterone (author's transl)]
[Urinary acid phosphatase and beta-glucuronidase activities in kidney diseases and following kidney transplantation]
Kidney Failure, Chronic
Activity of some lysosomal enzymes in peritoneal macrophages of patients with end-stage renal failure treated by intermittent peritoneal dialysis.
Changes in activity of selected lysosomal enzymes in peritoneal macrophages of renal failure patients on peritoneal dialysis.
Reversal of mineral ion homeostasis and soft-tissue calcification of klotho knockout mice by deletion of vitamin D 1alpha-hydroxylase.
Kwashiorkor
Arysulfatase and beta-glucuronidase activity in serum in kwashiorkor.
Lysosomal enzymuria in protein energy malnutrition.
Kyphosis
Beta-glucuronidase deficiency. A heterogeneous mucopolysaccharidosis.
Laryngeal Neoplasms
Activity of beta-glucuronidase in peripheral blood lymphocytes of patients with cancer of the larynx.
Effect of radiotherapy on the neutrophil and the lymphocyte enzymatic equipment and serum immunoglobulins in patients with cancer of the larynx.
Enzymatic deficiencies of the immune system cells in patients with cancer of the larynx and other malignancies.
Intracellular enzymatic response of lymphocytes and neutrophils in patients with cancer of the larynx.
The enzymatic equipment of neutrophils in patients with precancerous states of the larynx.
The intracellular enzymatic response of neutrophils and lymphocytes in patients with precancerous states and cancer of the larynx.
[Beta-glucuronidase of peripheral blood lymphocyte in patients with laryngeal neoplasms]
Learning Disabilities
Enzyme replacement therapy improves reproductive performance in mucopolysaccharidosis type VII mice but does not prevent postnatal losses.
Leishmaniasis
Enzymuria as an index of renal damage in canine leishmaniasis.
Leprosy
Acid mucopolysaccharide metabolism in leprosy. 2. Subcellular localization of hyaluronic acid and beta-glucuronidase in leprous infiltrates suggestive of a host-Mycobacterium leprae metabolic relationship.
Acid mucopolysaccharide metabolism in leprosy. 3. Hyaluronic acid mycobacterial growth enhancement, and growth suppression by saccharic acid and vitamin C as inhibitors of beta-glucuronidase.
Hydrolytic enzymes in leprosy sera.
Phagocytosis in leprosy. I. The levels of "diaphorase", beta-glucuronidase, acid phosphatase, alkaline phosphatase and lipase in circulating leucocytes.
Serum beta-glucuronidase in subtypes of leprosy.
Serum beta-glucuronidase levels in children with leprosy.
Leprosy, Borderline
Serum beta-glucuronidase in subtypes of leprosy.
Leprosy, Lepromatous
Acid mucopolysaccharide metabolism in leprosy. 2. Subcellular localization of hyaluronic acid and beta-glucuronidase in leprous infiltrates suggestive of a host-Mycobacterium leprae metabolic relationship.
Serum beta-glucuronidase in subtypes of leprosy.
Leprosy, Paucibacillary
Serum beta-glucuronidase in subtypes of leprosy.
Leprosy, Tuberculoid
Acid mucopolysaccharide metabolism in leprosy. 2. Subcellular localization of hyaluronic acid and beta-glucuronidase in leprous infiltrates suggestive of a host-Mycobacterium leprae metabolic relationship.
Leukemia
Acid alpha naphthyl acetate esterase and beta-glucuronidase in hairy cell leukemia.
Beta-glucuronidase activity of the white blood cells in human leukemias and Hodgkin's disease.
Beta-Glucuronidase studies in stem-cell leukemias.
Cytochemical staining with oil red O and for beta-glucuronidase in the diagnosis of acute leukemia.
Extracellular ATP-dependent suppression of proliferation and induction of differentiation of human HL-60 leukemia cells by distinct mechanisms.
Principal drug-metabolizing enzyme systems in L1210 leukemia sensitive or resistant to BCNU in vivo.
Transduction of hepatocytes after neonatal delivery of a Moloney murine leukemia virus based retroviral vector results in long-term expression of beta-glucuronidase in mucopolysaccharidosis VII dogs.
[Beta-glucuronidase and acid phosphatase activity in the blast cells of acute lymphoblastic and undifferentiated leukemia patients]
[Differential diagnostic significance of cytochemical studies of acid phosphatase and beta-glucuronidase in acute leukemia]
[Enzyme histochemical studies of malignant tumors in childhood. 2. Enzyme histochemical study on beta-glucuronidase and amylophosphorylase in acute leukemia]
[Usefulness of beta-glucuronidase activity determination in the differential diagnosis of acute leukemia]
Leukemia, Hairy Cell
Acid alpha naphthyl acetate esterase and beta-glucuronidase in hairy cell leukemia.
Leukemia, Lymphoid
[Lysosomal enzyme activity in white blood cells in leukemias]
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
beta-Glucuronidase is an optimal normalization control gene for molecular monitoring of chronic myelogenous leukemia.
The effect of total-ABL, GUS and B2M control genes on BCR-ABL monitoring by real-time RT-PCR.
[Lysosomal enzyme activity in white blood cells in leukemias]
Leukemia, Prolymphocytic
Cytochemistry of acid hydrolases in chronic B- and T-cell leukemias.
Leukemia, T-Cell
Cytochemistry of acid hydrolases in chronic B- and T-cell leukemias.
Leukocytosis
beta-Glucuronidase activity in cerebrospinal fluid pleocytosis due to urinary tract infection.
Leukopenia
Activation of plasma systems and blood cells by endotoxin in rabbits.
Complement activation and serum beta-glucuronidase level during hemodialysis.
Methylprednisolone prophylaxis protects against endotoxin-induced death in rabbits.
Leukoplakia
Deficiency of beta-glucuronidase in neutrophils from patients with precancerous states of the larynx.
Lymphocytes, neutrophils and serum immunoglobulins in patients with precancerous states of the larynx.
The enzymatic equipment of neutrophils in patients with precancerous states of the larynx.
The lymphocyte cytochemical equipment and serum immunoglobulins in patients with precancerous states of the larynx.
Leukoplakia, Oral
A comparative study of the beta-glucuronidase activity of the whole saliva in cases with and without oral leukoplakia.
Liver Cirrhosis
Changes in the catalytic activities of proteoglycan-degrading lysosomal enzymes in parenchymal and non-parenchymal liver cells and in serum during the development of experimental liver fibrosis.
Lysosomal enzymes in plasma, liver and spleen from rats with carbon tetrachloride-induced liver cirrhosis.
Serum alkaline-stable acid thiol proteinase--a possible marker for primary liver carcinoma.
Serum immunoreactive beta-glucuronidase determined by an enzyme-linked immunosorbent assay in patients with hepatic diseases.
Studies on the inhibition of experimental liver fibrosis. 2. The mechanism of the inhibition of liver fibrosis of rats due to carbon tetrachloride by elastase.
[Activity of serum beta-glucuronidase in liver cirrhosis and chronic hepatitis]
[Measurement of serum immunoreactive beta-glucuronidase: a possible serological marker for histological hepatic cell necrosis and to predict the histological progression of hepatitis]
Liver Diseases
Lysosomal enzymes in sera and granulocytes of patients with chronic liver diseases.
The occurrence of beta-glucuronidase in erythrocyte inclusions.
The significance of serum beta-glucuronidase activity in patients with liver disease; a preliminary report.
[Changes in liver glucuronyl-transferase and beta-glucuronidase tested with various substrates in liver diseases]
[Diagnostic evidence of serum beta-glucuronidase. 3. Behavior of serum beta glucuronidase activity in liver diseases in comparison owith results of other clinical-chemical studies]
[Estimation of the urinary aldosterone (author's transl)]
[Measurement of serum immunoreactive beta-glucuronidase: a possible serological marker for histological hepatic cell necrosis and to predict the histological progression of hepatitis]
[Studies on beta-glucuronidase. II. Clinical application of the assay method of beta-glucuronidase activity using p-nitrophenylglucuronide as the substrate. III. The significance of the serum beta-glucuronidase activity in patients with liver diseases, with special references to its relation with the serum transaminase activity, and to its characteristic behavior in cholangiolitic hepatitis.]
[The influence of glucose on the excretion of neutral 17-ketosteroid fractions by HCL and beta-glucuronidase, and of 17-ketogenic steroids in the urine of healthy subjects and patients with liver diseases.]
[The serum beta-glucuronidase in liver diseases]
Liver Neoplasms
Serum activities of lysosomal enzymes in patients with liver cell carcinoma.
Liver Neoplasms, Experimental
Beta-glucuronidase isozyme patterns of experimental hepatomas of rats.
Lung Injury
Biochemical and histological alterations in rats after acute nitrogen dioxide intoxication.
Characteristics of alveolar macrophages in experimental septic lung.
Increased pulmonary response to inhaled endotoxin in lactating rats.
Prostaglandin infusion and endotoxin-induced lung injury.
Lung Neoplasms
Activity of some lysosomal enzymes in peripheral blood lymphocytes of patients with lung cancer. A cytochemical study.
Cancer-associated alteration of beta-glucuronidase in human lung cancer: elevated activity and increased phosphorylation.
Cytochemical study of neutrophils from peripheral blood of patients with lung cancer.
Elucidation of the mechanism enabling tumor selective prodrug monotherapy.
Protein phosphorylation of beta-glucuronidase in human lung cancer--identification of serine- and threonine-phosphates.
[beta-Glucuronidase in human maxillary sinus and lung cancers: elevation of activity level and appearance of phosphorylated variant forms]
Lupus Erythematosus, Systemic
Signals of monocyte activation in patients with SLE.
[Serum level of beta-glucuronidase as potential indicator of disease activity in rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE)]
[The beta-glucuronidase activity in the blood cells and serum of patients with systemic lupus erythematosus]
Lymphadenopathy
Beta-glucuronidase activity of lymph node imprints from malignant lymphomas and chronic lymphocytic leukaemia.
Lymphoma
Beta-glucuronidase activity of lymph node imprints from malignant lymphomas and chronic lymphocytic leukaemia.
beta-Glucuronidase is transported slowly to lysosomes in BW5147 mouse lymphoma cells: evidence that the prelysosomal enzyme is not restricted to the endoplasmic reticulum.
Cerebrospinal fluid biochemical markers of central nervous system metastases.
Cytochemical examination of acid phosphatase and beta-glucuronidase enzymes in low-grade B cell non-Hodgkin's lymphomas.
Cytochemical reactions of normal and neoplastic lymphocytes.
Detection of mammalian cell mutagens in urine from carcinogen-dosed mice.
Ligatin binds phosphohexose residues on acidic hydrolases.
Measurements of CSF biochemical tumor markers in patients with meningeal carcinomatosis and brain tumors.
[Beta-glucuronidase activity and the cellular ultrastructure of the lymph nodes in malignant non-Hodgkin lymphomas]
Lymphoma, B-Cell
Construction and characterization of a fusion protein of single-chain anti-CD20 antibody and human beta-glucuronidase for antibody-directed enzyme prodrug therapy.
Lymphoma, T-Cell
Cell surface antigen phenotypes and enzyme expression patterns of two murine T-cell lymphomas derived from early and/or mature thymus cells.
Enzyme histochemistry of non-Hodgkin's lymphomas.
Ultrastructural cytochemistry of chronic T-cell leukaemias. A study with four acid hydrolases.
Lymphopenia
[Harmful chemical agents in electrochemical processing. II. Experimental studies on the toxic effects of nitric oxide and chlorine. Changes in peripheral blood in rats]
Lymphoproliferative Disorders
The lymphocyte beta-glucuronidase activity in lymphoproliferative disorders.
Lysosomal Storage Diseases
Abnormal osteoclast morphology and bone remodeling in a murine model of a lysosomal storage disease.
Active-site motifs of lysosomal acid hydrolases: invariant features of clan GH-A glycosyl hydrolases deduced from hydrophobic cluster analysis.
Adenovirus-mediated gene transfer and expression of human beta-glucuronidase gene in the liver, spleen, and central nervous system in mucopolysaccharidosis type VII mice.
Behavioral consequences of bone marrow transplantation in the treatment of murine mucopolysaccharidosis type VII.
Behavioural abnormalities in a murine model of a human lysosomal storage disease.
beta-Glucuronidase P408S, P415L mutations: evidence that both mutations combine to produce an MPS VII allele in certain Mexican patients.
Brain transplantation of genetically engineered human neural stem cells globally corrects brain lesions in the mucopolysaccharidosis type VII mouse.
Clinical response to persistent, low-level beta-glucuronidase expression in the murine model of mucopolysaccharidosis type VII.
Elimination of lysosomal storage in brains of MPS VII mice treated by intrathecal administration of an adeno-associated virus vector.
Encapsulation cell therapy for mucopolysaccharidosis type VII using genetically engineered immortalized human amniotic epithelial cells.
Evaluation of pathological manifestations of disease in mucopolysaccharidosis VII mice after neonatal hepatic gene therapy.
Expression in blood cells may contribute to biochemical and pathological improvements after neonatal intravenous gene therapy for mucopolysaccharidosis VII in dogs.
Extensive beta-glucuronidase activity in murine central nervous system after adenovirus-mediated gene transfer to brain.
Functional correction of established central nervous system deficits in an animal model of lysosomal storage disease with feline immunodeficiency virus-based vectors.
Gene therapy ameliorates cardiovascular disease in dogs with mucopolysaccharidosis VII.
Gene therapy for lysosomal storage disease: a no-brainer? Transplants of fibroblasts secreting high levels of beta-glucuronidase decrease lesions in the brains of mice with Sly syndrome, a lysosomal storage disease.
Gene transfer of low levels of beta-glucuronidase corrects hepatic lysosomal storage in a large animal model of mucopolysaccharidosis VII.
In utero transplantation of fetal liver cells in the mucopolysaccharidosis type VII mouse results in low-level chimerism, but overexpression of beta-glucuronidase can delay onset of clinical signs.
In-utero diagnosis of mucopolysaccharidosis type VII in a fetus with an enlarged nuchal translucency.
Intracranial injection of recombinant adeno-associated virus improves cognitive function in a murine model of mucopolysaccharidosis type VII.
Isolation and expression in Escherichia coli of a cDNA clone encoding human beta-glucuronidase.
Mechanism of shortened bones in mucopolysaccharidosis VII.
Microcapsules as bio-organs for somatic gene therapy.
Mucopolysaccharidosis type VII in the developing mouse fetus.
Mucopolysaccharidosis Type VII presenting with isolated neonatal ascites.
Murine mucopolysaccharidosis type VII. Characterization of a mouse with beta-glucuronidase deficiency.
Murine mucopolysaccharidosis type VII: the impact of therapies on the clinical course and pathology in a murine model of lysosomal storage disease.
Neonatal retroviral vector-mediated hepatic gene therapy reduces bone, joint, and cartilage disease in mucopolysaccharidosis VII mice and dogs.
Numerous transcriptional alterations in liver persist after short-term enzyme-replacement therapy in a murine model of mucopolysaccharidosis type VII.
Phenotype correction in retinal pigment epithelium in murine mucopolysaccharidosis VII by adenovirus-mediated gene transfer.
Production of MPS VII mouse (Gus(tm(hE540A x mE536A)Sly)) doubly tolerant to human and mouse beta-glucuronidase.
Systemic hyperosmolality improves beta-glucuronidase distribution and pathology in murine MPS VII brain following intraventricular gene transfer.
The beta-glucuronidase intracisternal A particle insertion model results in similar overall MPSVII phenotype as the single base deletion model when on the same C57BL/6J mouse background.
Treatment of lysosomal storage disease in MPS VII mice using a recombinant adeno-associated virus.
Variant clinical course of mucopolysaccharidosis type VII in two groups of mice carrying the same mutation.
Widespread biochemical correction of murine mucopolysaccharidosis type VII pathology by liver hydrodynamic plasmid delivery.
Widespread correction of lysosomal storage following intrahepatic injection of a recombinant adeno-associated virus in the adult MPS VII mouse.
Macular Degeneration
Progressive cone dystrophy associated with low alpha-L-fucosidase activity in serum and leukocytes.
Malabsorption Syndromes
[Activity of arylsulfatase and beta-glucuronidase in small intestine mucosa in children with malabsorption syndromes]
Malnutrition
Metabolism of lysosomal enzymes in the protein-deficient weanling rat.
Numerous transcriptional alterations in liver persist after short-term enzyme-replacement therapy in a murine model of mucopolysaccharidosis type VII.
Marfan Syndrome
Reduced activity of serum beta-glucuronidase in Marfan syndrome.
Mastitis
Assessment of beta-glucuronidase levels in goat's milk as an indicator of mastitis: comparison with other mastitis detection methods.
beta-Glucuronidase method to determine mastitis levels in goat milk.
Optimizing the fluorometric ?-glucuronidase assay in ruminant milk for a more precise determination of mastitis.
Significance of the presence of bovine milk beta-glucuronidase in mastitis detection.
Medulloblastoma
[Histochemical demonstration of glial enzyme activity. II. Reagent and neoplastic glia]
Melanoma
Decrease of cholesterol in mouse melanoma causes secretion of lysosomal enzymes.
How useful are housekeeping genes? Variable expression in melanoma metastases.
Intensely cytotoxic anthracycline prodrugs: glucuronides.
The mouse brown (b) locus protein has dopachrome tautomerase activity and is located in lysosomes in transfected fibroblasts.
Totally synthetic analogues of siastatin B. III. Trifluoroacetamide analogues having inhibitory activity for tumor metastasis.
[Activity and distribution of beta-glucuronidase and lactate dehydrogenase in human and transplantable melanomas of the mouse and golden hamster]
[Activity of beta-glucuronidase in B16 mouse melanoma]
[Renal dipeptidylpeptidase IV excretion in drug-induced kidney changes]
[Synthesis and melanoma inhibiting properties of 4-alkylpyrocatechol-2-O-beta-D-glucopyranosiduronic acids and their esters]
Melanoma, Amelanotic
Activity of some lysosomal hydrolases in the homogenates of transplantable melanotic and amelanotic melanoma in golden hamster (Mesocricetus auratus, Waterhouse).
Melanoma, Experimental
A solid-phase substrate of heparanase: its application to assay of human melanoma for heparan sulfate degradative activity.
Cathepsin B activity in B16 melanoma cells: a possible marker for metastatic potential.
Cathepsin B: association with plasma membrane in metastatic tumors.
Interaction of tumor and surrounding tissue of mice inoculated B16 melanoma variants in terms of enzyme activity.
Meningeal Carcinomatosis
Cerebrospinal fluid beta-glucuronidase activities in patients with central nervous system metastases.
Measurements of CSF biochemical tumor markers in patients with meningeal carcinomatosis and brain tumors.
[The cerebrospinal fluid concentrations of beta-glucuronidase and beta 2-microglobulin in neurological disorders]
Meningitis
Assay for beta-glucuronidase in cerebrospinal fluid: usefulness for the detection of neoplastic meningitis.
Cerebrospinal fluid biochemical markers of central nervous system metastases.
CSF beta-glucuronidase assay in the diagnosis of neoplastic meningitis.
[The cerebrospinal fluid concentrations of beta-glucuronidase and beta 2-microglobulin in neurological disorders]
Meningitis, Aseptic
beta-Glucuronidase activity in cerebrospinal fluid pleocytosis due to urinary tract infection.
Increased activity of lysosomal acid hydrolases in the cell-free cerebrospinal fluid of bacterial meningitis.
Meningitis, Bacterial
beta-Glucuronidase activity in cerebrospinal fluid pleocytosis due to urinary tract infection.
Beta-glucuronidase in the diagnosis of bacterial meningitis and response to treatment.
CSF lysosomal hydrolase activity as an aid in the diagnosis of bacterial meningitis.
Increased activity of lysosomal acid hydrolases in the cell-free cerebrospinal fluid of bacterial meningitis.
Rarity of bacterial and viral meningitis in areas of Western Greece with fewer than 2,000 inhabitants.
Meningitis, Viral
beta-Glucuronidase activity in cerebrospinal fluid pleocytosis due to urinary tract infection.
Mesenteric Lymphadenitis
Increased activity of lysosomal enzymes in the peritoneal fluid of bacterial peritonitis.
Migraine Disorders
Changes in serotonin metabolism during migraine attacks.
Mouth Neoplasms
A HISTOCHEMICAL OBSERVATION OF BETA-GLUCURONIDASE IN ORAL NEOPLASMS.
Mucolipidoses
Light and heavy lysosomes: characterization of N-acetyl-beta-D-hexosaminidase isolated from normal and I-cell disease lymphoblasts.
Lysosomal hydrolases in blood-derived macrophages of patients with I-cell disease.
Mucolipidoses II and III variants with normal N-acetylglucosamine 1-phosphotransferase activity toward alpha-methylmannoside are due to nonallelic mutations.
Postendocytic maturation of acid hydrolases: evidence of prelysosomal processing.
Mucopolysaccharidoses
A mutation (IVS8+0.6kbdelTC) creating a new donor splice site activates a cryptic exon in an Alu-element in intron 8 of the human beta-glucuronidase gene.
A novel model of murine mucopolysaccharidosis type VII due to an intracisternal a particle element transposition into the beta-glucuronidase gene: clinical and pathologic findings.
A rare late progression form of Sly syndrome mucopolysaccharidosis.
A single-base-pair deletion in the beta-glucuronidase gene accounts for the phenotype of murine mucopolysaccharidosis type VII.
Abnormal osteoclast morphology and bone remodeling in a murine model of a lysosomal storage disease.
Accumulation of abnormal amounts of glycosaminoglycans in murine mucopolysaccharidosis type VII neural progenitor cells does not alter the growth rate or efficiency of differentiation into neurons.
Acid hydrolases in serum from patients with lysosomal disorders.
Active site mutant transgene confers tolerance to human beta-glucuronidase without affecting the phenotype of MPS VII mice.
Adeno-associated virus type 5 reduces learning deficits and restores glutamate receptor subunit levels in MPS VII mice CNS.
Adenovirus-mediated gene therapy for corneal clouding in mice with mucopolysaccharidosis type VII.
Adenovirus-mediated gene therapy for mucopolysaccharidosis VII: involvement of cross-correction in wide-spread distribution of the gene products and long-term effects of CTLA-4Ig coexpression.
Adenovirus-mediated gene transfer and expression of human beta-glucuronidase gene in the liver, spleen, and central nervous system in mucopolysaccharidosis type VII mice.
Amphotropic and ecotropic retroviral vector viruses transduce midgestational murine fetal liver cells in a dual-chambered cocultivation system.
Behavioral consequences of bone marrow transplantation in the treatment of murine mucopolysaccharidosis type VII.
Behavioural abnormalities in a murine model of a human lysosomal storage disease.
beta-Glucuronidase deficiency as a cause of fetal hydrops.
Beta-glucuronidase deficiency in a girl with unusual clinical features.
Beta-glucuronidase deficiency mucopolysaccharidosis.
Beta-glucuronidase deficiency mucopolysaccharidosis. Repository identification No. GM-121.
Beta-glucuronidase deficiency mucopolysaccharidosis: methods for enzymatic diagnosis.
Beta-glucuronidase deficiency. A heterogeneous mucopolysaccharidosis.
Beta-glucuronidase deficiency: enzyme studies in an affected family and prenatal diagnosis.
Beta-glucuronidase P408S, P415L allele in a Mexican population: population screening in Guadalajara and prenatal diagnosis.
beta-Glucuronidase P408S, P415L mutations: evidence that both mutations combine to produce an MPS VII allele in certain Mexican patients.
Biochemical basis of the beta-glucuronidase gene defect causing canine mucopolysaccharidosis VII.
Bone marrow transplantation has a significant effect on enzyme levels and storage of glycosaminoglycans in tissues and in isolated hepatocytes of mucopolysaccharidosis type VII mice.
Characterization of the defective beta-glucuronidase activity in canine mucopolysaccharidosis type VII.
Clinical response to persistent, low-level beta-glucuronidase expression in the murine model of mucopolysaccharidosis type VII.
Cloning of the canine beta-glucuronidase cDNA, mutation identification in canine MPS VII, and retroviral vector-mediated correction of MPS VII cells.
Corneal transplantation in a patient with mucopolysaccharidosis type VII (Sly disease).
Correction of lysosomal storage in the liver and spleen of MPS VII mice by implantation of genetically modified skin fibroblasts.
Correction of murine mucopolysaccharidosis VII by a human beta-glucuronidase transgene.
Cross-correction of beta-glucuronidase deficiency by retroviral vector-mediated gene transfer.
Decreased lysosomal storage in the adult MPS VII mouse brain in the vicinity of grafts of retroviral vector-corrected fibroblasts secreting high levels of beta-glucuronidase.
Deletion mapping of the beta-glucuronidase gene.
Detection of active heteropolymeric beta-glucuronidase in hybrids between mouse cells and human fibroblasts with beta-glucuronidase deficiency.
Developmentally regulated mannose 6-phosphate receptor-mediated transport of a lysosomal enzyme across the blood-brain barrier.
Disappearance of lysosomal storage in spleen and liver of mucopolysaccharidosis VII mice after transplantation of genetically modified bone marrow cells.
Donor cell expansion is delayed following nonablative in utero transplantation to treat murine mucopolysaccharidosis type VII.
Elimination of lysosomal storage in brains of MPS VII mice treated by intrathecal administration of an adeno-associated virus vector.
Encapsulation cell therapy for mucopolysaccharidosis type VII using genetically engineered immortalized human amniotic epithelial cells.
Engraftment of human CD34+ cells leads to widespread distribution of donor-derived cells and correction of tissue pathology in a novel murine xenotransplantation model of lysosomal storage disease.
Enhanced secretion and uptake of beta-glucuronidase improves adeno-associated viral-mediated gene therapy of mucopolysaccharidosis type VII mice.
Enzyme replacement in murine mucopolysaccharidosis type VII: neuronal and glial response to beta-glucuronidase requires early initiation of enzyme replacement therapy.
Enzyme replacement therapy for murine mucopolysaccharidosis type VII.
Enzyme replacement therapy improves reproductive performance in mucopolysaccharidosis type VII mice but does not prevent postnatal losses.
Enzyme replacement with recombinant beta-glucuronidase in murine mucopolysaccharidosis type VII: impact of therapy during the first six weeks of life on subsequent lysosomal storage, growth, and survival.
Enzyme replacement with recombinant beta-glucuronidase in the newborn mucopolysaccharidosis type VII mouse.
Epinephrine enhances lysosomal enzyme delivery across the blood brain barrier by up-regulation of the mannose 6-phosphate receptor.
Extensive beta-glucuronidase activity in murine central nervous system after adenovirus-mediated gene transfer to brain.
Four novel mutations in mucopolysaccharidosis type VII including a unique base substitution in exon 10 of the beta-glucuronidase gene that creates a novel 5'-splice site.
Functional correction of CNS phenotypes in a lysosomal storage disease model using adeno-associated virus type 4 vectors.
Gene therapy for lysosomal disorders.
Gene therapy for murine mucopolysaccharidosis type VII.
Gene transfer of low levels of beta-glucuronidase corrects hepatic lysosomal storage in a large animal model of mucopolysaccharidosis VII.
Gene transfer to somatic tissues using retroviral vectors.
Genetic engineering of IgG-glucuronidase fusion proteins.
Glycosaminoglycan storage in cultured neonatal murine mucopolysaccharidosis type VII neuroglial cells and correction by beta-glucuronidase gene transfer.
Human beta-glucuronidase deficiency mucopolysaccharidosis: identification of cross-reactive antigen in cultured fibroblasts of deficient patients by enzyme immunoassay.
Human CD34+ hematopoietic progenitor cell-directed lentiviral-mediated gene therapy in a xenotransplantation model of lysosomal storage disease.
Identification and functional analysis of genetic variants of the human beta-glucuronidase in a German population sample.
Improvement of skeletal lesions in mice with mucopolysaccharidosis type VII by neonatal adenoviral gene transfer.
In utero transplantation of fetal liver cells in the mucopolysaccharidosis type VII mouse results in low-level chimerism, but overexpression of beta-glucuronidase can delay onset of clinical signs.
In vivo treatment of hemophilia A and mucopolysaccharidosis type VII using nonprimate lentiviral vectors.
In-utero diagnosis of mucopolysaccharidosis type VII in a fetus with an enlarged nuchal translucency.
Increased life span and correction of metabolic defects in murine mucopolysaccharidosis type VII after syngeneic bone marrow transplantation.
Inner ear pathology in the mucopolysaccharidosis VII mouse.
Intracisternal A-particle element transposition into the murine beta-glucuronidase gene correlates with loss of enzyme activity: a new model for beta-glucuronidase deficiency in the C3H mouse.
Intracranial injection of recombinant adeno-associated virus improves cognitive function in a murine model of mucopolysaccharidosis type VII.
Isolation and expression in Escherichia coli of a cDNA clone encoding human beta-glucuronidase.
Large scale analysis of the mutational landscape in ?-glucuronidase: A major player of mucopolysaccharidosis type VII.
Long-term and significant correction of brain lesions in adult mucopolysaccharidosis type VII mice using recombinant AAV vectors.
Long-term expression of beta-glucuronidase by genetically modified human neural progenitor cells grafted into the mouse central nervous system.
Low beta-glucuronidase enzyme activity and mutations in the human beta-glucuronidase gene in mild mucopolysaccharidosis type VII, pseudodeficiency and a heterozygote.
Lysosomal enzyme replacement of the brain with intravenous non-viral gene transfer.
Microcapsules as bio-organs for somatic gene therapy.
Molecular analysis of the beta-glucuronidase gene: novel mutations in mucopolysaccharidosis type VII and heterogeneity of the polyadenylation region.
Molecular basis of mucopolysaccharidosis type VII: replacement of Ala619 in beta-glucuronidase with Val.
Mucopolysaccharidosis type VII (beta-glucuronidase deficiency): a chronic variant with an oligosymptomatic severe skeletal dysplasia.
Mucopolysaccharidosis type VII in a German Shepherd Dog.
Mucopolysaccharidosis type VII in the developing mouse fetus.
Mucopolysaccharidosis Type VII presenting with isolated neonatal ascites.
Mucopolysaccharidosis type VII: characterization of mutations and molecular heterogeneity.
Murine mucopolysaccharidosis type VII. Characterization of a mouse with beta-glucuronidase deficiency.
Murine mucopolysaccharidosis type VII: long term therapeutic effects of enzyme replacement and enzyme replacement followed by bone marrow transplantation.
Murine mucopolysaccharidosis type VII: the impact of therapies on the clinical course and pathology in a murine model of lysosomal storage disease.
Mutant Enzymatic and Cytological Phenotypes in Cultured Human Fibroblasts.
Mutational studies in a patient with the hydrops fetalis form of mucopolysaccharidosis type VII.
Neonatal intramuscular injection with recombinant adeno-associated virus results in prolonged beta-glucuronidase expression in situ and correction of liver pathology in mucopolysaccharidosis type VII mice.
Neuropathology of murine mucopolysaccharidosis type VII.
New Strategies for Enzyme Replacement Therapy for Lysosomal Storage Diseases.
Non-immune hydrops fetalis caused by beta-glucuronidase deficiency (mucopolysaccharidosis VII). Study of a family with 3 affected siblings.
Optimization of electroporation for transfection of human fibroblast cell lines with origin-defective SV40 DNA: development of human transformed fibroblast cell lines with mucopolysaccharidoses (I-VII)
Overcoming the blood-brain barrier with high-dose enzyme replacement therapy in murine mucopolysaccharidosis VII.
Overexpression rescues the mutant phenotype of L176F mutation causing beta-glucuronidase deficiency mucopolysaccharidosis in two Mennonite siblings.
Phenotypic expression in mucopolysaccharidosis VII.
Photoreceptor degeneration and altered distribution of interphotoreceptor matrix proteoglycans in the mucopolysaccharidosis VII mouse.
Prenatal diagnosis of a heterozygote for mucopolysaccharidosis type VII (beta-glucuronidase deficiency).
Prevention of systemic clinical disease in MPS VII mice following AAV-mediated neonatal gene transfer.
Radiolabelled disaccharides for the assay of beta-D-glucuronidase activity and the detection of mucopolysaccharidosis type VII.
Rapid prenatal testing for human beta-glucuronidase deficiency (MPS VII).
Recombinant adeno-associated virus-mediated correction of lysosomal storage within the central nervous system of the adult mucopolysaccharidosis type VII mouse.
Recombinant human adenovirus: targeting to the human transferrin receptor improves gene transfer to brain microcapillary endothelium.
Restoration of normal lysosomal function in mucopolysaccharidosis type VII cells by retroviral vector-mediated gene transfer.
Retroviral cDNA transfer to the RPE: stable expression and modification of metabolism.
Significantly increased expression of beta-glucuronidase in the central nervous system of mucopolysaccharidosis type VII mice from the latency-associated transcript promoter in a nonpathogenic herpes simplex virus type 1 vector.
Somatic gene therapy for a neurodegenerative disease using microencapsulated recombinant cells.
Specific inhibition of human beta-D-glucuronidase and alpha-L-iduronidase by a trihydroxy pipecolic acid of plant origin.
Syngeneic bone marrow transplantation reduces the hearing loss associated with murine mucopolysaccharidosis type VII.
Systemic and central nervous system correction of lysosomal storage in mucopolysaccharidosis type VII mice.
The beta-glucuronidase intracisternal A particle insertion model results in similar overall MPSVII phenotype as the single base deletion model when on the same C57BL/6J mouse background.
Treatment of lysosomal storage disease in MPS VII mice using a recombinant adeno-associated virus.
Variant clinical course of mucopolysaccharidosis type VII in two groups of mice carrying the same mutation.
Widespread biochemical correction of murine mucopolysaccharidosis type VII pathology by liver hydrodynamic plasmid delivery.
Widespread correction of lysosomal storage following intrahepatic injection of a recombinant adeno-associated virus in the adult MPS VII mouse.
Widespread correction of lysosomal storage in the mucopolysaccharidosis type VII mouse brain with a herpes simplex virus type 1 vector expressing beta-glucuronidase.
[Mucopolysaccharidosis type VII: characterization of exonic point mutations and molecular heterogeneity]
Mucopolysaccharidosis I
Mucopolysaccharide diseases: A complex interplay between neuroinflammation, microglial activation and adaptive immunity.
Mutant Enzymatic and Cytological Phenotypes in Cultured Human Fibroblasts.
Radiographic evaluation of bones and joints in mucopolysaccharidosis I and VII dogs after neonatal gene therapy.
Upregulation of elastase activity in aorta in mucopolysaccharidosis I and VII dogs may be due to increased cytokine expression.
Mucopolysaccharidosis III
Mucopolysaccharide diseases: A complex interplay between neuroinflammation, microglial activation and adaptive immunity.
Storage correction in cells of patients suffering from mucopolysaccharidoses types IIIA and VII after treatment with genistein and other isoflavones.
Mucopolysaccharidosis IV
An autophagic vacuolar myopathy-like disorder presenting as nonimmune hydrops in a female fetus.
Mucopolysaccharidosis VII
A mutation (IVS8+0.6kbdelTC) creating a new donor splice site activates a cryptic exon in an Alu-element in intron 8 of the human beta-glucuronidase gene.
A novel model of murine mucopolysaccharidosis type VII due to an intracisternal a particle element transposition into the beta-glucuronidase gene: clinical and pathologic findings.
A pseudodeficiency allele (D152N) of the human beta-glucuronidase gene.
A rare late progression form of Sly syndrome mucopolysaccharidosis.
A single-base-pair deletion in the beta-glucuronidase gene accounts for the phenotype of murine mucopolysaccharidosis type VII.
Abnormal osteoclast morphology and bone remodeling in a murine model of a lysosomal storage disease.
Accumulation of abnormal amounts of glycosaminoglycans in murine mucopolysaccharidosis type VII neural progenitor cells does not alter the growth rate or efficiency of differentiation into neurons.
Active site mutant transgene confers tolerance to human beta-glucuronidase without affecting the phenotype of MPS VII mice.
Adeno-associated virus type 5 reduces learning deficits and restores glutamate receptor subunit levels in MPS VII mice CNS.
Adenoviral vector-mediated beta-glucuronidase cDNA transfer to treat MPS VII RPE in vitro.
Adenovirus-mediated gene therapy for corneal clouding in mice with mucopolysaccharidosis type VII.
Adenovirus-mediated gene therapy for mucopolysaccharidosis VII: involvement of cross-correction in wide-spread distribution of the gene products and long-term effects of CTLA-4Ig coexpression.
Adenovirus-mediated gene transfer and expression of human beta-glucuronidase gene in the liver, spleen, and central nervous system in mucopolysaccharidosis type VII mice.
Altered lumbar spine structure, biochemistry, and biomechanical properties in a canine model of mucopolysaccharidosis type VII.
Atypical radiological features of beta-glucuronidase deficiency (mucopolysaccharidosis VII) occurring in an elderly patient from an inbred kindred.
Behavioral consequences of bone marrow transplantation in the treatment of murine mucopolysaccharidosis type VII.
Behavioural abnormalities in a murine model of a human lysosomal storage disease.
Beta-glucuronidase deficiency (mucopolysaccharidosis type VII).
beta-Glucuronidase deficiency as a cause of fetal hydrops.
Beta-glucuronidase deficiency as a cause of prenatally diagnosed non-immune hydrops fetalis.
Beta-glucuronidase deficiency as cause of recurrent hydrops fetalis: the first early prenatal diagnosis by chorionic villus sampling.
Beta-glucuronidase deficiency in a dog: a model of human mucopolysaccharidosis VII.
Beta-glucuronidase deficiency in a girl with unusual clinical features.
Beta-glucuronidase deficiency mucopolysaccharidosis.
Beta-glucuronidase deficiency mucopolysaccharidosis. Repository identification No. GM-121.
Beta-glucuronidase deficiency mucopolysaccharidosis: methods for enzymatic diagnosis.
Beta-glucuronidase deficiency. A heterogeneous mucopolysaccharidosis.
Beta-glucuronidase deficiency: enzyme studies in an affected family and prenatal diagnosis.
beta-Glucuronidase deficiency: identification of an affected fetus with simultaneous sampling of chorionic villus and amniotic fluid.
Beta-glucuronidase P408S, P415L allele in a Mexican population: population screening in Guadalajara and prenatal diagnosis.
beta-Glucuronidase P408S, P415L mutations: evidence that both mutations combine to produce an MPS VII allele in certain Mexican patients.
Biochemical basis of the beta-glucuronidase gene defect causing canine mucopolysaccharidosis VII.
Biodistribution, kinetics, and efficacy of highly phosphorylated and non-phosphorylated beta-glucuronidase in the murine model of mucopolysaccharidosis VII.
Bone marrow transplantation has a significant effect on enzyme levels and storage of glycosaminoglycans in tissues and in isolated hepatocytes of mucopolysaccharidosis type VII mice.
Brain transplantation of genetically engineered human neural stem cells globally corrects brain lesions in the mucopolysaccharidosis type VII mouse.
Characterization of the defective beta-glucuronidase activity in canine mucopolysaccharidosis type VII.
Chemically modified beta-glucuronidase crosses blood-brain barrier and clears neuronal storage in murine mucopolysaccharidosis VII.
Clinical response to persistent, low-level beta-glucuronidase expression in the murine model of mucopolysaccharidosis type VII.
Cloning of the canine beta-glucuronidase cDNA, mutation identification in canine MPS VII, and retroviral vector-mediated correction of MPS VII cells.
Corneal transplantation in a patient with mucopolysaccharidosis type VII (Sly disease).
Correction of lysosomal storage in the liver and spleen of MPS VII mice by implantation of genetically modified skin fibroblasts.
Correction of murine mucopolysaccharidosis VII by a human beta-glucuronidase transgene.
Cross-correction of beta-glucuronidase deficiency by retroviral vector-mediated gene transfer.
Deletion mapping of the beta-glucuronidase gene.
Delivery of a retroviral vector expressing human beta-glucuronidase to the liver and spleen decreases lysosomal storage in mucopolysaccharidosis VII mice.
Detection of active heteropolymeric beta-glucuronidase in hybrids between mouse cells and human fibroblasts with beta-glucuronidase deficiency.
Developmentally regulated mannose 6-phosphate receptor-mediated transport of a lysosomal enzyme across the blood-brain barrier.
Disappearance of lysosomal storage in spleen and liver of mucopolysaccharidosis VII mice after transplantation of genetically modified bone marrow cells.
Donor cell expansion is delayed following nonablative in utero transplantation to treat murine mucopolysaccharidosis type VII.
Efficient and persistent expression of beta-glucuronidase gene in CD34+ cells from human umbilical cord blood by retroviral vector.
Elimination of lysosomal storage in brains of MPS VII mice treated by intrathecal administration of an adeno-associated virus vector.
Encapsulation cell therapy for mucopolysaccharidosis type VII using genetically engineered immortalized human amniotic epithelial cells.
Engraftment of human CD34+ cells leads to widespread distribution of donor-derived cells and correction of tissue pathology in a novel murine xenotransplantation model of lysosomal storage disease.
Enhanced secretion and uptake of beta-glucuronidase improves adeno-associated viral-mediated gene therapy of mucopolysaccharidosis type VII mice.
Enzyme replacement in murine mucopolysaccharidosis type VII: neuronal and glial response to beta-glucuronidase requires early initiation of enzyme replacement therapy.
Enzyme replacement therapy for murine mucopolysaccharidosis type VII.
Enzyme replacement therapy improves reproductive performance in mucopolysaccharidosis type VII mice but does not prevent postnatal losses.
Enzyme replacement with recombinant beta-glucuronidase in murine mucopolysaccharidosis type VII: impact of therapy during the first six weeks of life on subsequent lysosomal storage, growth, and survival.
Enzyme replacement with recombinant beta-glucuronidase in the newborn mucopolysaccharidosis type VII mouse.
Epinephrine enhances lysosomal enzyme delivery across the blood brain barrier by up-regulation of the mannose 6-phosphate receptor.
Evaluation of pathological manifestations of disease in mucopolysaccharidosis VII mice after neonatal hepatic gene therapy.
Expression in blood cells may contribute to biochemical and pathological improvements after neonatal intravenous gene therapy for mucopolysaccharidosis VII in dogs.
Extensive beta-glucuronidase activity in murine central nervous system after adenovirus-mediated gene transfer to brain.
Feline mucopolysaccharidosis VII due to beta-glucuronidase deficiency.
Four novel mutations in mucopolysaccharidosis type VII including a unique base substitution in exon 10 of the beta-glucuronidase gene that creates a novel 5'-splice site.
Functional correction of CNS phenotypes in a lysosomal storage disease model using adeno-associated virus type 4 vectors.
Gene therapy ameliorates cardiovascular disease in dogs with mucopolysaccharidosis VII.
Gene therapy for lysosomal disorders.
Gene therapy for lysosomal storage disease: a no-brainer? Transplants of fibroblasts secreting high levels of beta-glucuronidase decrease lesions in the brains of mice with Sly syndrome, a lysosomal storage disease.
Gene therapy for murine mucopolysaccharidosis type VII.
Gene therapy/cell therapy for lysosomal storage disease.
Gene transfer of low levels of beta-glucuronidase corrects hepatic lysosomal storage in a large animal model of mucopolysaccharidosis VII.
Glycosaminoglycan storage in cultured neonatal murine mucopolysaccharidosis type VII neuroglial cells and correction by beta-glucuronidase gene transfer.
High level expression and export of beta-glucuronidase from murine mucopolysaccharidosis VII cells corrected by a double-copy retrovirus vector.
Human beta-glucuronidase deficiency mucopolysaccharidosis: identification of cross-reactive antigen in cultured fibroblasts of deficient patients by enzyme immunoassay.
Human CD34+ hematopoietic progenitor cell-directed lentiviral-mediated gene therapy in a xenotransplantation model of lysosomal storage disease.
Identification and functional analysis of genetic variants of the human beta-glucuronidase in a German population sample.
Identification of new markers for neurodegeneration process in the mouse model of Sly disease as revealed by expression profiling of selected genes.
Improvement of skeletal lesions in mice with mucopolysaccharidosis type VII by neonatal adenoviral gene transfer.
In utero transplantation of fetal liver cells in the mucopolysaccharidosis type VII mouse results in low-level chimerism, but overexpression of beta-glucuronidase can delay onset of clinical signs.
In vivo treatment of hemophilia A and mucopolysaccharidosis type VII using nonprimate lentiviral vectors.
In-utero diagnosis of mucopolysaccharidosis type VII in a fetus with an enlarged nuchal translucency.
Incidence of the mucopolysaccharidoses in Northern Ireland.
Increased life span and correction of metabolic defects in murine mucopolysaccharidosis type VII after syngeneic bone marrow transplantation.
Infused Fc-tagged beta-glucuronidase crosses the placenta and produces clearance of storage in utero in mucopolysaccharidosis VII mice.
Inner ear pathology in the mucopolysaccharidosis VII mouse.
Intracisternal A-particle element transposition into the murine beta-glucuronidase gene correlates with loss of enzyme activity: a new model for beta-glucuronidase deficiency in the C3H mouse.
Intracranial injection of recombinant adeno-associated virus improves cognitive function in a murine model of mucopolysaccharidosis type VII.
Isolation and expression in Escherichia coli of a cDNA clone encoding human beta-glucuronidase.
Large scale analysis of the mutational landscape in ?-glucuronidase: A major player of mucopolysaccharidosis type VII.
Long-term and significant correction of brain lesions in adult mucopolysaccharidosis type VII mice using recombinant AAV vectors.
Long-term expression of beta-glucuronidase by genetically modified human neural progenitor cells grafted into the mouse central nervous system.
Long-term normalization in the central nervous system, ocular manifestations, and skeletal deformities by a single systemic adenovirus injection into neonatal mice with mucopolysaccharidosis VII.
Low beta-glucuronidase activity in a healthy member of a family with mucopolysaccharidosis VII.
Low beta-glucuronidase enzyme activity and mutations in the human beta-glucuronidase gene in mild mucopolysaccharidosis type VII, pseudodeficiency and a heterozygote.
Lymphocytes, neutrophils and serum immunoglobulins in patients with precancerous states of the larynx.
Lysosomal storage diseases presenting as transient or persistent hydrops fetalis.
Mechanism of shortened bones in mucopolysaccharidosis VII.
Microcapsules as bio-organs for somatic gene therapy.
Missense models [Gustm(E536A)Sly, Gustm(E536Q)Sly, and Gustm(L175F)Sly] of murine mucopolysaccharidosis type VII produced by targeted mutagenesis.
Molecular analysis of a patient with hydrops fetalis caused by beta-glucuronidase deficiency, and evidence for additional pseudogenes.
Molecular analysis of patients with beta-glucuronidase deficiency presenting as hydrops fetalis or as early mucopolysaccharidosis VII.
Molecular analysis of the beta-glucuronidase gene: novel mutations in mucopolysaccharidosis type VII and heterogeneity of the polyadenylation region.
Molecular basis of feline beta-glucuronidase deficiency: an animal model of mucopolysaccharidosis VII.
Molecular basis of mucopolysaccharidosis type VII: replacement of Ala619 in beta-glucuronidase with Val.
Mucopolysaccharidosis type VII as a cause of recurrent non-immune hydrops fetalis.
Mucopolysaccharidosis type VII in a German Shepherd Dog.
Mucopolysaccharidosis type VII in the developing mouse fetus.
Mucopolysaccharidosis Type VII presenting with isolated neonatal ascites.
Mucopolysaccharidosis type VII: characterization of mutations and molecular heterogeneity.
Mucopolysaccharidosis VII as cause of fetal hydrops in early pregnancy.
Mucopolysaccharidosis VII: postmortem biochemical and pathological findings in a young adult with beta-glucuronidase deficiency.
Mucopolysaccharidosis. VII. Beta-glucuronidase deficiency.
Murine mucopolysaccharidosis type VII. Characterization of a mouse with beta-glucuronidase deficiency.
Murine mucopolysaccharidosis type VII: long term therapeutic effects of enzyme replacement and enzyme replacement followed by bone marrow transplantation.
Murine mucopolysaccharidosis type VII: the impact of therapies on the clinical course and pathology in a murine model of lysosomal storage disease.
Mutational analysis in longest known survivor of mucopolysaccharidosis type VII.
Mutational studies in a patient with the hydrops fetalis form of mucopolysaccharidosis type VII.
Mutations and polymorphisms in GUSB gene in mucopolysaccharidosis VII (Sly Syndrome).
Neonatal intramuscular injection with recombinant adeno-associated virus results in prolonged beta-glucuronidase expression in situ and correction of liver pathology in mucopolysaccharidosis type VII mice.
Neonatal retroviral vector-mediated hepatic gene therapy reduces bone, joint, and cartilage disease in mucopolysaccharidosis VII mice and dogs.
Neural progenitor cell engraftment corrects lysosomal storage throughout the MPS VII mouse brain.
Neuropathology of murine mucopolysaccharidosis type VII.
New Strategies for Enzyme Replacement Therapy for Lysosomal Storage Diseases.
Non-immune hydrops fetalis caused by beta-glucuronidase deficiency (mucopolysaccharidosis VII). Study of a family with 3 affected siblings.
Nonablative neonatal marrow transplantation attenuates functional and physical defects of beta-glucuronidase deficiency.
Numerous transcriptional alterations in liver persist after short-term enzyme-replacement therapy in a murine model of mucopolysaccharidosis type VII.
Ocular and electrophysiological findings in a patient with Sly syndrome.
Optimization of electroporation for transfection of human fibroblast cell lines with origin-defective SV40 DNA: development of human transformed fibroblast cell lines with mucopolysaccharidoses (I-VII)
Overcoming the blood-brain barrier with high-dose enzyme replacement therapy in murine mucopolysaccharidosis VII.
Overexpression rescues the mutant phenotype of L176F mutation causing beta-glucuronidase deficiency mucopolysaccharidosis in two Mennonite siblings.
Phenotype correction in retinal pigment epithelium in murine mucopolysaccharidosis VII by adenovirus-mediated gene transfer.
Phenotypic expression in mucopolysaccharidosis VII.
Photoreceptor degeneration and altered distribution of interphotoreceptor matrix proteoglycans in the mucopolysaccharidosis VII mouse.
Postmortem observations on beta-glucuronidase deficiency presenting as hydrops fetalis.
Prevention of systemic clinical disease in MPS VII mice following AAV-mediated neonatal gene transfer.
Production of MPS VII mouse (Gus(tm(hE540A x mE536A)Sly)) doubly tolerant to human and mouse beta-glucuronidase.
Quantitation and biosynthesis of beta-glucuronidase cross-reactive material in fibroblasts from patients with mucopolysaccharidosis VII.
Radiolabelled disaccharides for the assay of beta-D-glucuronidase activity and the detection of mucopolysaccharidosis type VII.
Rapid prenatal testing for human beta-glucuronidase deficiency (MPS VII).
Recombinant adeno-associated virus-mediated correction of lysosomal storage within the central nervous system of the adult mucopolysaccharidosis type VII mouse.
Restoration of normal lysosomal function in mucopolysaccharidosis type VII cells by retroviral vector-mediated gene transfer.
Reversal of pathology in murine mucopolysaccharidosis type VII by somatic cell gene transfer.
Significantly increased expression of beta-glucuronidase in the central nervous system of mucopolysaccharidosis type VII mice from the latency-associated transcript promoter in a nonpathogenic herpes simplex virus type 1 vector.
Single cell analysis and selection of living retrovirus vector-corrected mucopolysaccharidosis VII cells using a fluorescence-activated cell sorting-based assay for mammalian beta-glucuronidase enzymatic activity.
Somatic gene therapy for a neurodegenerative disease using microencapsulated recombinant cells.
Storage correction in cells of patients suffering from mucopolysaccharidoses types IIIA and VII after treatment with genistein and other isoflavones.
Structural features of normal and mutant human lysosomal glycoside hydrolases deduced from bioinformatics analysis.
Sustained production of beta-glucuronidase from localized sites after AAV vector gene transfer results in widespread distribution of enzyme and reversal of lysosomal storage lesions in a large volume of brain in mucopolysaccharidosis VII mice.
Syngeneic bone marrow transplantation reduces the hearing loss associated with murine mucopolysaccharidosis type VII.
Systemic hyperosmolality improves beta-glucuronidase distribution and pathology in murine MPS VII brain following intraventricular gene transfer.
The enzymatic equipment of neutrophils in patients with precancerous states of the larynx.
The HIV Tat protein transduction domain improves the biodistribution of beta-glucuronidase expressed from recombinant viral vectors.
Therapeutic neonatal hepatic gene therapy in mucopolysaccharidosis VII dogs.
Transduction of hepatocytes after neonatal delivery of a Moloney murine leukemia virus based retroviral vector results in long-term expression of beta-glucuronidase in mucopolysaccharidosis VII dogs.
Transplantation and magnetic resonance imaging of canine neural progenitor cell grafts in the postnatal dog brain.
Treatment of lysosomal storage disease in MPS VII mice using a recombinant adeno-associated virus.
Treatment of lysosomal storage disorders: cell therapy and gene therapy.
Treatment of MPS VII (Sly disease) by allogeneic BMT in a female with homozygous A619V mutation.
Unusually mild course of beta-glucuronidase deficiency in two brothers (mucopolysaccharidosis VII).
Variant clinical course of mucopolysaccharidosis type VII in two groups of mice carrying the same mutation.
Variation in the phenotypic expression of beta-glucuronidase deficiency.
Widespread biochemical correction of murine mucopolysaccharidosis type VII pathology by liver hydrodynamic plasmid delivery.
Widespread correction of lysosomal storage following intrahepatic injection of a recombinant adeno-associated virus in the adult MPS VII mouse.
Widespread correction of lysosomal storage in the mucopolysaccharidosis type VII mouse brain with a herpes simplex virus type 1 vector expressing beta-glucuronidase.
Widespread gene transduction to the central nervous system by adenovirus in utero: implication for prenatal gene therapy to brain involvement of lysosomal storage disease.
[Beta-glucuronidase deficiency in the circulating neutrophils of patients with stationary simple psoriasis]
[Beta-glucuronidase deficiency in the peripheral neutrophils in diabetes mellitus]
[Mucopolysaccharidesis Type VII resulting from beta-glucuronidase deficiency. Report of one family]
[Mucopolysaccharidosis type VII: characterization of exonic point mutations and molecular heterogeneity]
Multiple Myeloma
Prognostic correlation of plasma cell acid phosphatase and beta-glucuronidase in multiple myeloma: a Southwest Oncology Group study.
Multiple Sclerosis
Invited review: Bovine milk fat globule membrane as a potential nutraceutical.
Leucocyte glutathione peroxidase activity and selenium level in multiple sclerosis.
Lysosomal hydrolases in cerebrospinal fluid of multiple sclerosis patients. A follow-up study.
Muscular Atrophy
Juvenile neurogenic muscle atrophy with lysosomal enzyme deficiencies: new disease or variant of mucopolysaccharidosis?
Lysosomal and nonlysosomal hydrolases of skeletal muscle in neuromuscular diseases.
Muscular Dystrophies
A preliminary study of serum beta-glucuronidase enzyme activity in progressive muscular dystrophies.
Lysosomal and nonlysosomal hydrolases of skeletal muscle in neuromuscular diseases.
Myalgia
Effect of eccentric exercise on muscle oxidative metabolism in humans.
Mycoses
Advances in the development of host resistance in corn to aflatoxin contamination by Aspergillus flavus
Advances in the Development of Host Resistance in Corn to Aflatoxin Contamination by Aspergillus flavus.
Myelodysplastic Syndromes
Quantitative cytochemistry of blood neutrophils in myelodysplastic syndromes and chronic granulocytic leukaemia.
Myeloproliferative Disorders
Gene dosage effect for beta-glucuronidase (GUSB) in monosomy 7 cells of patients with myeloproliferative disorders.
Gene dosage effect in acquired monosomy 7: distinct behaviour of beta-glucuronidase and phosphoserine phosphatase.
Platelet lysosomal enzymes are normal in myeloproliferative disorders.
Myocardial Infarction
Alterations in the heart lysosomal stability in isoproterenol induced myocardial infarction in rats.
Features of lysosomal proteolytic enzyme activity in infarcted myocardium.
Influence of isoproterenol-induced myocardial infarction on certain glycohydrolases and cathepsins in rats.
Plasma lysosomal enzyme activity in acute myocardial infarction.
Serum and urinary beta-galactosidase and beta-glucuronidase activity in patients with acute myocardial infarction.
Synergistic effect of nicorandil and amlodipine on lysosomal hydrolases during experimental myocardial infarction in rats.
[Behavior of the histochemically demonstrable activity of beta-glucuronidase in experimental myocardial infarct of the rat]
[Histochemical studies of neutrophils in myocardial infarct patients]
Myocardial Ischemia
Release of lysosomal enzymes during ischemic injury of canine myocardium.
Myopia
Lysosomal enzymes in tear fluids from patients with ocular diseases.
Lysosomal enzymes in the serum of patients with with Behçet's disease.
Progressive cone dystrophy associated with low alpha-L-fucosidase activity in serum and leukocytes.
n-sulfoglucosamine sulfohydrolase deficiency
Storage correction in cells of patients suffering from mucopolysaccharidoses types IIIA and VII after treatment with genistein and other isoflavones.
Necrobiosis Lipoidica
Serum beta-glucuronidase activity in human diabetes mellitus, granuloma annulare and necrobiosis lipoidica.
Nematode Infections
The tobacco Cel7 gene promoter is auxin-responsive and locally induced in nematode feeding sites of heterologous plants.
Neoplasm Metastasis
A minimal toxicity approach to cancer therapy: possible role of beta-glucuronidase.
Cerebrospinal fluid beta-glucuronidase activities in patients with central nervous system metastases.
Cerebrospinal fluid biochemical markers of central nervous system metastases.
Embryonic morphogen nodal promotes breast cancer growth and progression.
How useful are housekeeping genes? Variable expression in melanoma metastases.
Interaction of tumor and surrounding tissue of mice inoculated B16 melanoma variants in terms of enzyme activity.
Sensitivity and specificity of single and combined tumour markers in the diagnosis of leptomeningeal metastasis from breast cancer.
Totally synthetic analogues of siastatin B. III. Trifluoroacetamide analogues having inhibitory activity for tumor metastasis.
Tumour markers in the cerebrospinal fluid of patients with central nervous system metastases from extracranial malignancies.
Neoplasm Micrometastasis
Embryonic morphogen nodal promotes breast cancer growth and progression.
Neoplasms
?-Glucuronidase-responsive prodrugs for selective cancer chemotherapy: an update.
A heparin-coated circuit reduces complement activation and the release of leukocyte inflammatory mediators during extracorporeal circulation in a rabbit.
A histochemical study on the distribution and localization of beta-glucuronidase activity in cerebral tumors.
A methylester of the glucuronide prodrug DOX-GA3 for improvement of tumor-selective chemotherapy.
A minimal toxicity approach to cancer therapy: possible role of beta-glucuronidase.
A novel doxorubicin-glucuronide prodrug DOX-GA3 for tumour-selective chemotherapy: distribution and efficacy in experimental human ovarian cancer.
A phase I trial of hypoxoside as an oral prodrug for cancer therapy--absence of toxicity.
A study of serum glycosidases in cancer.
A-72363 A-1, A-2, and C, novel heparanase inhibitors from Streptomyces nobilis SANK 60192, II. Biological activities.
Activity of beta-glucuronidase in peripheral blood lymphocytes of patients with cancer of the larynx.
Activity of some lysosomal enzymes in neutrophils from peripheral blood of patients with digestive tract cancer at different clinical stages of the disease. A cytochemical study.
Activity of some lysosomal hydrolases in the homogenates of transplantable melanotic and amelanotic melanoma in golden hamster (Mesocricetus auratus, Waterhouse).
Alterations in morphology, arginase, and beta-glucuronidase within a clone of mouse tumor cells in vitro.
An assessment of the effects of glucocorticoids on degranulation, chemotaxis, binding to vascular endothelium and formation of leukotriene B4 by purified human neutrophils.
Anti-tumour activity and toxicity of the new prodrug 9-aminocamptothecin glucuronide (9ACG) in mice.
Antiangiogenesis targeting tumor microenvironment synergizes glucuronide prodrug antitumor activity.
Anticancer prodrugs for application in monotherapy: targeting hypoxia, tumor-associated enzymes, and receptors.
Antitumor effect of i.p. dopamine in mice bearing Ehrlich ascites carcinoma.
Application of microalgal fucoxanthin for the reduction of colon cancer risk: inhibitory activity of fucoxanthin against beta-glucuronidase and DLD-1 cancer cells.
Benzyl ether-linked glucuronide derivative of 10-hydroxycamptothecin designed for selective camptothecin-based anticancer therapy.
beta-D-glucuronidase activity in malignant neoplasms of man: a histochemical study.
beta-Glucoronidase and the gastric epithelial cell. A study using organ culture.
Beta-glucuronidase activities in tumors of the nervous system.
Beta-glucuronidase activity in adrenals of patients with or without cancer.
Beta-glucuronidase activity in human female genital cancer.
Beta-glucuronidase activity in neutrophils of patients with malignancies.
Beta-glucuronidase activity in tumors. Accumulation of radioiodinated phenolphthalein.
Beta-glucuronidase in human cutaneous tumours.
Beta-glucuronidase studies in women. 2. Cancer of the cervix uteri.
Beta-glucuronidase studies in women. VI. Premenopausal vaginal fluid values in relation to invasive cervical cancer.
Beta-Glucuronidase studies in women. VII. Premenopausal vaginal-fluid-beta-glucuronidase values in relation to in situ cancer of the cervix.
Beta-glucuronidase-cleavable prodrugs of O6-benzylguanine and O6-benzyl-2'-deoxyguanosine.
Beta-glucuronidase-mediated drug release.
Biochemical changes in tumor cells caused by antitumor agent. IV. Influence of antitumor agent on isozyme pattern of beta-glucuronidase.
Biochemical changes in tumor cells caused by antitumor agents. II. Effect of several antitumor agents in vivo and in vitro on beta-glucuronidase and two other lysosomal enzymes of Yoshida sarcoma cells.
Bis(3,5-diiodo-2,4,6-trihydroxyphenyl)squaraine: A novel candidate in photodynamic therapy for skin cancer models in vivo.
BONE TUMOURS AND THEIR ENZYMES. A STUDY OF THE PHOSPHATASES, NON-SPECIFIC ESTERASES AND BETA-GLUCURONIDASE OF OSTEOGENIC AND CARTILAGINOUS TUMOURS, FIBROBLASTIC AND GIANT-CELL LESIONS.
Calcium-D-glucarate.
Cancer chemotherapy: a SN-38 (7-ethyl-10-hydroxycamptothecin) glucuronide prodrug for treatment by a PMT (Prodrug MonoTherapy) strategy.
Cancer-associated alteration of beta-glucuronidase in human lung cancer: elevated activity and increased phosphorylation.
Cancer-preventing attributes of probiotics: an update.
Cathepsin B activity in B16 melanoma cells: a possible marker for metastatic potential.
Cationic polymeric gene delivery of beta-glucuronidase for doxorubicin prodrug therapy.
Cerebrospinal fluid beta-glucuronidase activities in patients with central nervous system metastases.
Cerebrospinal fluid biochemical markers of central nervous system metastases.
Cerebrospinal fluid tumour markers in patients treated for meningeal malignancy.
Characterization of macrophage cell line A640-BB-2: A640-BB-2 resembles peritoneal exudate macrophages in cell morphology, tumor cell recognition, responsiveness to immunomodulator OK-432 and lysosomal enzyme activity.
Chimeric TNT-3/human beta-glucuronidase fusion proteins for antibody-directed enzyme prodrug therapy (ADEPT).
Clinical laboratory procedures in cancer diagnosis; serum prostatic acid phosphatase and vaginal fluid beta-glucuronidase.
Combination of intratumoral injections of vaccinia virus MVA expressing GM-CSF and immunization with DNA vaccine prolongs the survival of mice bearing HPV16 induced tumors with downregulated expression of MHC class I molecules.
Comparative activation states of tumor-associated and peritoneal macrophages from mice bearing an induced fibrosarcoma.
Comparison of mouse and human colon tumors with regard to phase I and phase II drug-metabolizing enzyme systems.
Comparison of the beta-Glucuronidase Activity of Normal, Tumor, and Lymph Node Tissues of Surgical Patients.
Comparison of vaginal and cervical beta-glucuronidase in relation to cancer of the cervix and uterus.
Conjugated catechol derivatives in a transplantable islet cell tumour of the golden hamster.
Construction and characterization of a fusion protein of single-chain anti-CD20 antibody and human beta-glucuronidase for antibody-directed enzyme prodrug therapy.
Corynebacterium parvum treatment of P388 tumor-bearing mice. I. Lysosomal enzyme levels in adherent peritoneal cells and peritoneal lavage fluid.
CSF beta-glucuronidase assay as an aid to the diagnosis of diffuse meningeal dissemination of neoplasm.
Cure of malignant ascites and generation of protective immunity by monoclonal antibody-targeted activation of a glucuronide prodrug in rats.
Cytochemical analysis of acid hydrolases expression during phorbol diester (TPA)-driven differentiation of B-chronic lymphocytic leukaemia cells in vitro.
Cytochemical study of neutrophils from peripheral blood of patients with lung cancer.
Cytotoxicity of aniline mustard glucuronide alone or in a combination with glucose in Walker cells in culture and sarcoma-180 tumour bearing animals.
Demonstration of enhanced potency of a chimeric somatostatin-dopamine molecule, BIM-23A387, in suppressing growth hormone and prolactin secretion from human pituitary somatotroph adenoma cells.
Design and synthesis of water-soluble glucuronide derivatives of camptothecin for cancer prodrug monotherapy and antibody-directed enzyme prodrug therapy (ADEPT).
Detection and quantification of D: -glucuronic acid in human bile using (1)H NMR spectroscopy: relevance to the diagnosis of pancreatic cancer.
Detoxifying cancer causing agents to prevent cancer.
Development and optimization of an enzyme-linked immunosorbent assay employing two murine monoclonal antibodies for absolute quantitation of human beta-glucuronidase.
Dietary and demographic correlates of serum beta-glucuronidase activity.
Differential effects of mineral dusts on the in vitro activation of alveolar macrophage eicosanoid and cytokine release.
Differential effects of surgical suture materials in 1,2-dimethylhydrazine-induced rat intestinal neoplasia.
Direct in vivo observation of 5-fluorouracil release from a prodrug in human tumors heterotransplanted in nude mice: a magnetic resonance study.
Distribution and pharmacokinetics of the prodrug daunorubicin-GA3 in nude mice bearing human ovarian cancer xenografts.
Distribution of cyclic 3',5'-phosphodiesterase, monoamine oxidase & beta-glucuronidase in liver tumours induced by technical grade hexachlorocyclohexane in inbred swiss mice.
Dopamine 2 and somatostatin 1-5 receptors coexpression in clinically non-functioning pituitary adenomas.
Dose optimization of a doxorubicin prodrug (HMR 1826) in isolated perfused human lungs: low tumor pH promotes prodrug activation by beta-glucuronidase.
Effect of Bifidobacterium longum and inulin on gut bacterial metabolism and carcinogen-induced aberrant crypt foci in rats.
Effect of coconut cake on the bacterial enzyme activity in 1,2-dimethyl hydrazine induced colon cancer.
Effect of dietary fiber on the activity of intestinal and fecal beta-glucuronidase activity during 1,2-dimethylhydrazine induced colon carcinogenesis.
Effect of exogenous beta-glucuronidase on the carcinogenicity of 1,2-dimethylhydrazine in rats: evidence that carcinogenic intermediates form conjugates and act through their subsequent enzymatic release.
Effect of ginger on bacterial enzymes in 1,2-dimethylhydrazine induced experimental colon carcinogenesis.
Effect of milk fermented with a Lactobacillus helveticus R389(+) proteolytic strain on the immune system and on the growth of 4T1 breast cancer cells in mice.
Effect of radiotherapy on the neutrophil and the lymphocyte enzymatic equipment and serum immunoglobulins in patients with cancer of the larynx.
Effect of two kinds of pectin and guar gum on 1,2-dimethylhydrazine initiation of colon tumors and on fecal beta-glucuronidase activity in the rat.
Effects of calcium glucarate on the promotion of diethylnitrosamine-initiated altered hepatic foci in rats.
Effects of differing purified cellulose, pectin, and hemicellulose fiber diets on fecal enzymes in 1,2-dimethylhydrazine-induced rat colon carcinogenesis.
Effects of flunixin, tolfenamic acid, R(-) and S(+) ketoprofen on the response of equine synoviocytes to lipopolysaccharide stimulation.
Effects of small bowel transection, resection, or bypass in 1,2-dimethylhydrazine-induced rat intestinal neoplasia.
Effects of tumour cell culture supernatants on some biochemical activities of macrophages.
Elucidation of the mechanism enabling tumor selective prodrug monotherapy.
Endo- and exoglycosidases in an experimental rat osteosarcoma.
Enhanced cytostatic effectiveness of aniline mustard against 7,12-dimethylbenz[a]anthracene-induced rat mammary tumors during regression in response to ovariectomy.
Enhanced uptake of doxorubicin into bronchial carcinoma: beta-glucuronidase mediates release of doxorubicin from a glucuronide prodrug (HMR 1826) at the tumor site.
Enhancement of lysosomal enzyme activity by recombinant human tumor necrosis factor and its role in tumor cell killing in vitro.
Enhancing effect of carrageenan on the induction of rat colonic tumors by 1,2-dimethylhydrazine and its relation to beta-glucuronidase activities in feces and other tissues.
Enzymatic deficiencies of the immune system cells in patients with cancer of the larynx and other malignancies.
Enzyme activity and distribution in rat prostatic adenocarcinoma.
Enzyme activity in relation to cancer: inhibition of urinary beta-glucuronidase of patients with cancer of the bladder by oral administration of 1:4-saccharolactone and related compounds.
Enzyme activity in relation to cancer; the urinary beta-glucuronidase activity of patients suffering from malignant disease.
Enzyme activity profiles in mouse teratocarcinomas. A quantitative ultramicroscale analysis.
Enzyme histochemical study on bone tumors.
Enzyme-activated Prodrug Therapy Enhances Tumor-specific Replication of Adenovirus Vectors.
Establishment and characterization of transplantable tumor derived from a spontaneous malignant fibrous histiocytoma in the mouse.
Expression and function of beta-glucuronidase in pancreatic cancer: potential role in drug targeting.
Expression of active human beta-glucuronidase in Sf9 cells infected with recombinant baculovirus.
Flavones and flavonols may have clinical potential as CK2 inhibitors in cancer therapy.
Flavonoid-related regulation of auxin accumulation in Agrobacterium tumefaciens-induced plant tumors.
Fusion protein mediated prodrug activation (FMPA) in vivo.
Glucuronidase deconjugation in inflammation.
Glucuronides in anti-cancer therapy.
Glycosidases in cancer and invasion.
Histochemistry of therapeutically relevant enzymes in human tumours transplanted into severe combined immunodeficient (SCID) mice: nitric oxide synthase-associated diaphorase, beta-D-glucuronidase and non-specific alkaline phosphatase.
Histological grading, histochemistry, and electron microscopy of scirrhous carcinoma of the breast.
Hydrolytic enzyme activities of the nervous system.
Hydrolytic enzymes in meningiomal subtypes.
Identification and localization of transformed cells in agrobacterium tumefaciens-induced plant tumors
Impediments to Enhancement of CPT-11 Anticancer Activity by E. coli Directed Beta-Glucuronidase Therapy.
In situ localization of endogenous cytokinins during shooty tumor development on Eucalyptus globulus Labill.
In-vitro Biological Study to Evaluate the Toxic Potentials of Fibrous Materials.
Increased activity of lysosomal enzymes in the peritoneal fluid of patients with gynecologic cancers and pelvic inflammatory disease.
Increased activity of lysosomal glycohydrolases in glioma tissue and surrounding areas from human brain.
Increased expression of a high molecular weight matrix component in rat hepatocellular carcinoma.
Inhibition of human breast cancer growth by GCP (genistein combined polysaccharide) in xenogeneic athymic mice: involvement of genistein biotransformation by beta-glucuronidase from tumor tissues.
Insect-resistant chrysanthemum calluses by introduction of a Bacillus thuringiensis crystal protein gene.
Interaction of tumor and surrounding tissue of mice inoculated B16 melanoma variants in terms of enzyme activity.
Intracellular enzymatic response of lymphocytes and neutrophils in patients with cancer of the larynx.
Invited review: Bovine milk fat globule membrane as a potential nutraceutical.
Lactic acid bacteria as probiotics.
Local enzymatic hydrolysis of an endogenously generated metabolite can enhance CPT-11 anticancer efficacy.
Localization of beta-glucuronidase in normal and cancer cells.
Localization of beta-glucuronidase in some human tumors.
Lung toxicity induced by intratracheal instillation of size-fractionated tire particles.
Lymphocytes, neutrophils and serum immunoglobulins in patients with precancerous states of the larynx.
Lysosomal enzymes in macrophages of colonic tumors induced in rats by 1,2-dimethylhydrazine dihydrochloride.
Main drug-metabolizing enzyme systems in human breast tumors and peritumoral tissues.
Measurements of CSF biochemical tumor markers in patients with meningeal carcinomatosis and brain tumors.
Membrane-localized activation of glucuronide prodrugs by beta-glucuronidase enzymes.
Metabolism and pharmacokinetics of the anti-tumour agent 2,3,5-trimethyl-6-(3-pyridylmethyl)1,4-benzoquinone (CV-6504).
Metabolism, uptake, and excretion of a D-glucaric acid salt and its potential use in cancer prevention.
Micro-PET imaging of beta-glucuronidase activity by the hydrophobic conversion of a glucuronide probe.
Modulation of intestinal environment by prebiotic germinated barley foodstuff prevents chemo-induced colonic carcinogenesis in rats.
Origin of the increased activity of beta-glucuronidase in the soluble fraction of rat mammary tumors during ovariectomy-induced regression.
Pancreatic secretory abnormalities precede appearance of tumors of the pancreas in hamsters treated with bis-(2-oxopropyl)-N-nitrosamine.
Peripheral T-cell lymphomas. Immunologic and enzyme histochemical analysis of 15 cases.
PET imaging of ?-glucuronidase activity by an activity-based 124I-trapping probe for the personalized glucuronide prodrug targeted therapy.
Phenotypic heterogeneity of human T-cell malignancies: demonstration by monoclonal antibodies and cytochemical markers.
Poly(ethylene glycol) modification of beta-glucuronidase-antibody conjugates for solid-tumor therapy by targeted activation of glucuronide prodrugs.
Potentiation of antitumor immunity by antibody-directed enzyme prodrug therapy.
Principal xenobiotic-metabolizing enzyme systems in human head and neck squamous cell carcinoma.
Probiotics, Prebiotics and Synbiotics: A Role in Chemoprevention for Colorectal Cancer?
Prodrug Mono Therapy: synthesis and biological evaluation of an etoposide glucuronide-prodrug.
Pronounced antitumor efficacy by extracellular activation of a doxorubicin-glucuronide prodrug after adenoviral vector-mediated expression of a human antibody-enzyme fusion protein.
Pronounced antitumor efficacy of doxorubicin when given as the prodrug DOX-GA3 in combination with a monoclonal antibody beta-glucuronidase conjugate.
Protective role of luteolin in 1,2-dimethylhydrazine induced experimental colon carcinogenesis.
Purification and characterization of a lysosomal form and a variant form of beta-glucuronidase from the rat basophil leukaemia tumour.
Pyrrolo[2,1-c][1,4]benzodiazepine-beta-glucuronide prodrugs with a potential for selective therapy of solid tumors by PMT and ADEPT strategies.
Quantitation of free beta-glucuronidase activity in several tumours of rats.
Regulation of human beta-glucuronidase by A23187 and thapsigargin in the hepatoma cell line HepG2.
Relationship of beta-glucuronidase to differentiation and invasion of human colorectal carcinoma.
Salivary and serum inflammatory mediators among pre-conception women with periodontal disease.
Secretagogue response of azaserine-induced rat pancreatic acinar tumors in vivo.
Selective Cancer Therapy by Extracellular Activation of a Highly Potent Glycosidic Duocarmycin Analogue.
Serum enzymes in ovarian carcinoma.
Stability of the new prodrug 9-aminocamptothecin glucuronide (9ACG) in the presence of human serum albumin.
Studies of estrogen induced renal tumours in male Syrian hamsters. I. Cytochemical studies of lysosomal enzymes acid phosphatase and beta-glucuronidase.
Studies on the changes of serum beta-glucuronidase activity of the cancer hosts and the mechanism of inhibiting effects of glucuronic acid and the related substances upon the glucuronidase activities.
Studies on urinary isozymes of lactic dehydrogenase and beta-glucuronidase in patients with bladder tumors.
Study of some lysosomal glycohydrolases in tumors of the nervous system.
Sugar industry sponsorship of germ-free rodent studies linking sucrose to hyperlipidemia and cancer: An historical analysis of internal documents.
Synthesis and cytotoxic activity of a glucuronylated prodrug of nornitrogen mustard.
Synthesis and Evaluation of [(18)F]-FEAnGA as a PET Tracer for beta-Glucuronidase Activity.
Synthesis and iodine-125 labelling of glucuronide compounds for combined chemo- and radiotherapy of cancer.
The 1993 ISOBM Abbott Award Lecture. Isozymes, tumor markers and oncodevelopmental biology.
The carcinogenic effect of cigarette smoke. The effect of cigarette smoke on human gastric mucosal cells in organ culture.
The cytochemical demonstration of beta-glucuronidase in colon neoplasms of rats exposed to azoxymethane.
The effect of radiation and polymyxin B sulfate on the serum beta-glucuronidase activity level in cancer patients. A preliminary report.
The effect of total-ABL, GUS and B2M control genes on BCR-ABL monitoring by real-time RT-PCR.
The efficacy of the anthracycline prodrug daunorubicin-GA3 in human ovarian cancer xenografts.
The enzymatic equipment of neutrophils in patients with precancerous states of the larynx.
The in vitro metabolism of irinotecan (CPT-11) by carboxylesterase and beta-glucuronidase in human colorectal tumours.
The intracellular enzymatic response of neutrophils and lymphocytes in patients with precancerous states and cancer of the larynx.
The intracellular enzymatic response of neutrophils and lymphocytes in patients with precancerous states and cancer of the uterine cervix.
The locations of cathepsin activity and beta-glucuronidase in the Guerin T8 tumour.
The presence of high beta-glucuronidase activity in cancer tissue.
The regulatory functions of the rolB and rolC genes of Agrobacterium rhizogenes are conserved in the homologous genes (Ngrol) of Nicotiana glauca in tobacco genetic tumors.
The relationship of the enzyme beta-glucuronidase to cancer of the cervix uteri.
The relative contributions of carboxylesterase and beta-glucuronidase in the formation of SN-38 in human colorectal tumours.
The role of beta-glucuronidase in drug disposition and drug targeting in humans.
The role of beta-glucuronidase in induction of apoptosis by genistein combined polysaccharide (GCP) in xenogeneic mice bearing human mammary cancer cells.
The significance of beta-glucuronidase content in the vaginal fluid of patients with cancer of the uterus.
The significance of tissue beta-glucuronidase content in patients with cancer of the uterus.
Therapeutic trial of aniline mustard in patients with advanced cancer. Comparison of therapeutic response with cytochemical assessment of tumor cell beta-glucuronidase activity.
Tumor inhibition and hematological improvements by dopamine analog 3,4-dihydroxybenzylamine in mice bearing transplantable carcinoma.
Tumor-selective prodrug activation by fusion protein-mediated catalysis.
Tumor-targeted cell killing with 8-hydroxyquinolyl-glucuronide.
Tumor-targeted delivery of 8-hydroxyquinoline.
Tumor-targeting prodrug-activating bacteria for cancer therapy.
Tumour markers in the cerebrospinal fluid of patients with central nervous system metastases from extracranial malignancies.
Urinary beta-glucuronidase activity as an initial screening test for urinary tract malignancy in high risk patients. Comparison with conventional urine cytologic evaluation.
Urinary beta-glucuronidase activity in cancer of the bladder and other diseases.
Urinary beta-glucuronidase in renal cell carcinoma.
Urinary beta-glucuronidase in screening and followup of primary urinary tract malignancy.
Use of tartaric acid resistance of beta-glucuronidase for the characterization of cancer cells in pleural effusions.
Verapamil regulates activity and mRNA-expression of human beta-glucuronidase in HepG2 cells.
Wheat bran and psyllium diets: effects on N-methylnitrosourea-induced mammary tumorigenesis in F344 rats.
[A study on activity of beta-glucuronidase in serum and secretion from upper respiratory tract in patients with head and neck malignant tumors]
[Beta-glucuronidase activity in human malignant neoplasms and various experimental conditions. Histochemical research]
[beta-glucuronidase activity in human tumors of the lung and of the mammary gland (author's transl)]
[beta-Glucuronidase activity in some tumors of orthopedic interest.]
[Beta-glucuronidase activity of the vaginal fluid in cancer of the uterine cervix.]
[Beta-glucuronidase in human gastric juice in patients with malignant neoplasms of the stomach.]
[Beta-glucuronidase in the early diagnosis of cancer of the cervix uteri]
[Chemical constituents of stems and branches of Adina polycephala]
[Chemotherapy-induced diarrhea]
[Detection and distribution of the hydrolytic enzymes beta-D-glucuronidase, beta-D-galactosidase, beta-D-glucosidase and arylsulfatase in intracranial tumors]
[Diagnosis of cancer and isozymes. 3. Trial of enzymic diagnosis of cancer by beta-glucuronidase isozyme]
[Enzyme histochemical studies of malignant tumors in childhood. 2. Enzyme histochemical study on beta-glucuronidase and amylophosphorylase in acute leukemia]
[Evaluation of the usefulness of analysis of beta-glucuronidase levels in patients with superficial cancer and papilloma of the bladder]
[Fluorometric determination of beta-glucuronidase activity in the blood of healthy & sick persons, with special reference to cancer.]
[Histochemical studies of enzymes in malignant tumors in childhood. 1. Histochemical study of beta-glucuronidase in solid tumors]
[Interactions between desoxycholic acid glucuronides and glucuronidase (author's transl)]
[Investigations into the clinical significance of beta-glucuronidase as tumour indicator during radiation therapy of patients with carcinoma of the bladder (author's transl)]
[New means for the prophylaxis of colon cancer with the use of beta-glucuronidase inhibitors]
[Relationship between cancer of the large intestine and beta-glucuronidase activity]
[Serum ribonuclease and beta-glucuronidase activity in patients with malignant ovarian tumors treated surgically and followed up with combined chemotherapy]
[Stability of urinary beta-glucuronidase during collection of urine and daily elimination curve in malignant tumors of the bladder.]
[Study on beta-glucuronidase activity in children. 3. Beta-glucuronidase activity of the blood and tumor tissue in malignant tumor in children]
[Study on urinary beta-glucuronidase and alkaline phosphatase activities as indicators of CDDP renal toxicity]
[The cerebrospinal fluid concentrations of beta-glucuronidase and beta 2-microglobulin in neurological disorders]
[The role of beta-glucuronidase in the tumor process and cancer prevention]
[Urinary and plasma beta-glucuronidase and their relation to vesical neoplasia]
[Urinary beta-glucuronidase activity in malignant neoplasms of the ovary.]
[Urinary beta-glucuronidase activity in population samples (Sicilian and Libyan) having varied frequency of occurrence of vesical neoplasms.]
Neoplastic Processes
Assay for beta-glucuronidase in cerebrospinal fluid: usefulness for the detection of neoplastic meningitis.
Nephritis
Macrophages from inflamed but not normal glomeruli are unresponsive to anti-inflammatory cytokines.
Nephrosis
Beta-glucuronidase in leukocytes, plasma, and urine of patients with nephrosis undergoing treatment with ACTH.
Nephrotic Syndrome
[Activity of alanine aminopeptidase, beta-glucuronidase and N-acetyl-beta-d-glucosaminidase in urine of children with nephrotic syndrome]
[DETERMINATION OF THE ENZYMATIC ACTIVITY IN CHILDHOOD. IV. BETA-GLUCURONIDASE IN THE SERUM AND URINE IN NEPHROTIC SYNDROME.]
Nervous System Diseases
[Studies on the activity of leucine and glycine aminopeptidases and beta-glucuronidase in the cerebrospinal fluid and serum in nervous system diseases]
[The cerebrospinal fluid concentrations of beta-glucuronidase and beta 2-microglobulin in neurological disorders]
Nervous System Neoplasms
Beta-glucuronidase activities in tumors of the nervous system.
Neurilemmoma
[Demonstration and distribution of the enzymes: beta-D-glucuronidase, beta-D-galactosidase, beta-D-glucosidase, and arylsulfatase in neurinomas.]
Neuroblastoma
Direct transfer of beta-glucuronidase from mouse macrophages to other types of cell.
Primary adult human astrocytes as an ex vivo vehicle for beta-glucuronidase delivery in the brain.
Neuromuscular Diseases
Lysosomal and nonlysosomal hydrolases of skeletal muscle in neuromuscular diseases.
Neuronal Ceroid-Lipofuscinoses
Neuronal ceroid-lipofuscinosis. Studies of granulocyte enzyme activities.
Neutropenia
[Effect of lithium carbonate on the beta-glucuronidase activity in neutrophils of healthy persons and of patients with neutropenia]
Obesity
[ESTIMATION OF THE BETA-GLUCURONIDASE ACTIVITY OF THE SERUM IN OBESITY.]
Osteoarthritis
Gene expression and activity of cartilage-degrading glycosidases in human rheumatoid arthritis and osteoarthritis synovial fibroblasts.
Synovial fluid exoglycosidases are predictors of rheumatoid arthritis and are effective in cartilage glycosaminoglycan depletion.
Osteochondrodysplasias
Juvenile neurogenic muscle atrophy with lysosomal enzyme deficiencies: new disease or variant of mucopolysaccharidosis?
Ovarian Cysts
Increased activity of lysosomal enzymes in the peritoneal fluid of patients with gynecologic cancers and pelvic inflammatory disease.
Ovarian Neoplasms
A new application for liposomes in cancer therapy. Immunoliposomes bearing enzymes (immuno-enzymosomes) for site-specific activation of prodrugs.
Design of immuno-enzymosomes with maximum enzyme targeting capability: effect of the enzyme density on the enzyme targeting capability and cell binding properties.
Pancreatic Neoplasms
A study of serum glycosidases in cancer.
Clinical significance of TGF- beta1 and beta-glucuronidase synchronous detection in human pancreatic cancer.
Expression and function of beta-glucuronidase in pancreatic cancer: potential role in drug targeting.
Pancreatitis
Complement activation and clearance in acute illness and injury: evidence for C5a as a cell-directed mediator of the adult respiratory distress syndrome in man.
Effect of high fiber intake on pancreatic lysosomal stability in ethanol-fed rats.
Lysosomal-mitochondrial interrelationships in damage to the liver in acute experimental pancreatitis in dogs. Treatment with prostacyclin (PGI2).
Rifampicin, halothane and glucose as mediators of lysosomal enzyme release and tissue damage.
Role of platelet-activating factor in pancreatitis-associated acute lung injury in the rat.
The effect of heparin on lysosomes of the dog pancreas during acute experimental pancreatitis.
The lysosomal hydrolases in acute experimental pancreatitis in dogs treated with glucagon.
Ultrastructural studies of experimental acute pancreatitis.
[Activity and subcellular distribution of lysosomal enzymes in acute pancreatitis induced by CDE diet in mice]
Papilloma
Deficiency of beta-glucuronidase in neutrophils from patients with precancerous states of the larynx.
Lymphocytes, neutrophils and serum immunoglobulins in patients with precancerous states of the larynx.
The enzymatic equipment of neutrophils in patients with precancerous states of the larynx.
The lymphocyte cytochemical equipment and serum immunoglobulins in patients with precancerous states of the larynx.
[Evaluation of the usefulness of analysis of beta-glucuronidase levels in patients with superficial cancer and papilloma of the bladder]
Paraproteinemias
[Plasma cell beta-glucuronidase and monoclonal gammapathies (author's transl)]
Pelvic Inflammatory Disease
Increased activity of lysosomal enzymes in the peritoneal fluid of patients with gynecologic cancers and pelvic inflammatory disease.
Peptic Ulcer
[Beta-glucuronidase in human gastric juice in patients with gastroduodenitis and gastroduodenal ulcer.]
Periodontal Attachment Loss
Beta-glucuronidase activity in saliva: relationship to clinical periodontal parameters.
Periodontal Diseases
Advances in periodontal diagnosis. 7. Proteolytic and hydrolytic enzymes link with periodontitis.
Analysis of human gingival tissue and gingival crevicular fluid beta-glucuronidase activity in specific periodontal diseases.
Beta-glucuronidase activity in human gingiva in health and periodontal disease.
Beta-glucuronidase activity in saliva: relationship to clinical periodontal parameters.
Comparative analysis of GCF beta-glucuronidase level in diabetic and nondiabetic patients with chronic periodontitis: A clinicobiochemical study.
CrossLaps and beta-glucuronidase in peri-implant and gingival crevicular fluid.
Enzyme activity in crevicular fluid in relation to metabolic control of diabetes and other periodontal risk factors.
Immunoglobulin isotypes in gingival crevicular fluid: possible protective role of IgA.
Increased intracellular levels of lysosomal beta-glucuronidase in peripheral blood PMNs from humans with rapidly progressive periodontitis.
Interleukin-8 and beta-glucuronidase in gingival crevicular fluid.
Salivary and serum inflammatory mediators among pre-conception women with periodontal disease.
The relationship of beta-glucuronidase activity in crevicular fluid to clinical parameters of periodontal disease. Findings from a multicenter study.
[Beta-glucuronidase, beta-acetylgalactosaminidase and acid phosphatase activities in whole saliva of the patients with periodontal disease (author's transl)]
[Microbiological and biochemical characteristics of inflammatory tissues in the periodontium]
[Study on relation between periodontal disease and beta-glucuronidase activity. I. Beta-glucuronidase activities in serum, whole saliva and filtrated saliva from patients with periodontal disease (author's transl)]
[Study on relation between periodontal disease and beta-glucuronidase activity. III. beta-glucuronidase activities in gingival tissue from patients with periodontal disease (author's transl)]
[Study on the relation between periodontal disease and Beta-glucuronidase activity. II. Beta-glucuronidase activities in gingival fluid from patients with periodontal disease (author's transl)]
Periodontal Pocket
[Changes of factors on disease activity in advancing periodontitis]
Periodontitis
Comparative analysis of GCF beta-glucuronidase level in diabetic and nondiabetic patients with chronic periodontitis: A clinicobiochemical study.
Development of a risk profile for periodontal disease: microbial and host response factors.
Enzyme activity in crevicular fluid in relation to metabolic control of diabetes and other periodontal risk factors.
Host mediators in gingival crevicular fluid: implications for the pathogenesis of periodontal disease.
Increased intracellular levels of beta-glucuronidase in polymorphonuclear leucocytes from humans with rapidly progressive periodontitis.
Increased intracellular levels of lysosomal beta-glucuronidase in peripheral blood PMNs from humans with rapidly progressive periodontitis.
Infantile agranulocytosis with survival into adolescence: periodontal manifestations and laboratory findings. A case report.
Morphology of azurophil lysosomes in polymorphonuclear leukocytes from humans with rapidly progressive periodontitis.
Relationship of subgingival plaque flora to lysosomal and cytoplasmic enzyme activity in gingival crevicular fluid.
Risk factors for periodontitis in HIV patients.
Secretory function of neutrophilic leukocytes of the patients with periodontal diseases.
The host response in gingival crevicular fluid: potential applications in periodontitis clinical trials.
The influence of diabetes on gingival crevicular fluid beta-glucuronidase and interleukin-8.
The relationship of beta-glucuronidase activity in crevicular fluid to probing attachment loss in patients with adult periodontitis. Findings from a multicenter study.
[Enzymatic protective systems of saliva in inflammation of the periodontium]
[UDP-glucose dehydrogenase and beta-glucuronidase activities in the gingival tissue of dogs with experimental periodontitis (author's transl)]
Peripheral Nervous System Diseases
Neurotoxic effects of the combined exposure to carbon disulphide and ethanol in rats.
Peritonitis
Effect of sodium glycyrrhetinate on chemical peritonitis in rats.
Increased activity of lysosomal enzymes in the peritoneal fluid of bacterial peritonitis.
Pharyngitis
Biotypes of group A streptococci isolated from children.
Plasmacytoma
The effect of TEPC-183 plasmacytoma growth on beta-glucuronidase activity in serum and tissues of tumor-bearing mice.
[Cytochemical demonstration of beta-glucuronidase and beta-acetylglucosaminidase in plasmacytoma]
Pleural Effusion
Diagnostic potential of lysosomal hydrolases in body cavity effusions.
Some biological and pharmacological properties of inflammatory exudates.
Use of tartaric acid resistance of beta-glucuronidase for the characterization of cancer cells in pleural effusions.
Usefulness of monitoring beta-glucuronidase in pleural effusions.
Pneumonia
Comparative acute toxicity of four nickel compounds to F344 rat lung.
Potassium Deficiency
Potassium regulates plasma testosterone and renal ornithine decarboxylase in mice.
Pre-Eclampsia
Serum beta-glucuronidase levels during toxemia of pregnancy.
[Beta-glucuronidase activity and pregnancy toxemias.]
[Serum beta-glucuronidase activity in early and late pregnancy toxemia and in uteroplacental apoplexy]
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Acute leukemia with unusual cytoplasmic inclusions: a cytochemical and ultrastructural study.
Correlation of cerebrospinal fluid beta-glucuronidase activity with plasma methotrexate concentrations in leukemic children receiving high-dose methotrexate.
Non-T, non-B childhood acute lymphoblastic leukemia. Correlation between cytochemical markers and first complete remission.
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
Differential diagnostic value of acid phosphatase and beta-glucuronidase in acute leukaemia.
Pregnancy, Ectopic
[Placental lactogen level and activity of oxytocinase, beta-glucuronidase and thermostable alkaline phosphatase isoenzyme in blood serum of women with ectopic pregnancy]
Prostatic Hyperplasia
Beta-glucuronidase activity in prostatic carcinoma and benign prostatic hyperplasia.
Beta-glucuronidase activity of the epithelial cells and stroma cells in prostatic hyperplasia. A brief communication.
Prostatic Neoplasms
The prognostic value of acid phosphatase and beta-glucuronidase activity in biopsy specimens from patients with reactivated prostatic cancer.
Therapeutic trial of aniline mustard in patients with advanced cancer. Comparison of therapeutic response with cytochemical assessment of tumor cell beta-glucuronidase activity.
[A study on beta-glucuronidase in urine and serum, especially on the relation between the histological change and the activity of this enzyme in therapy of prostatic cancer.]
Protein Deficiency
[Beta-glucuronidase activity in the gastric juice and gastric mucosa of rats subjected to protein deficiency]
Protein-Energy Malnutrition
Changes in serum lysosomal hydrolases in marasmus.
Lysosomal enzymuria in protein energy malnutrition.
Metabolism of lysosomal enzymes in the protein-deficient weanling rat.
Urinary excretion of beta-glucuronidase in protein-calorie malnutrition.
Proteinuria
Organic solvents and chronic glomerulonephritis: a cross-sectional study with negative findings for aliphatic and alicyclic C5-C7 hydrocarbons.
The excretion of urinary enzymes, proteins and creatinine in patients receiving cisplatinum.
[Diagnosis of rejection of the transplanted kidney with respect to urine values of sodium, beta-glucuronidase, lysozyme and proteinuria]
[Urinary enzymes as a marker of the preclinical stage of diabetic nephropathy]
Psoriasis
Activity of some lysosomal enzyme in rheumatoid and psoriatic arthritis.
Beta-glucuronidase of neutrophils in psoriasis.
Decreased extracellular release of granule enzymes from in vitro-stimulated polymorphonuclear leukocytes in guttate psoriasis.
[Activity of beta-glucuronidase and acid phosphatase in fractions of granulocytes isolated from PMNL in peripheral blood of patients with psoriasis]
[Beta-glucuronidase deficiency in the circulating neutrophils of patients with stationary simple psoriasis]
[Histochemical studies on beta-glucuronidase activity in psoriasis, basilioma and spinocellular carcinoma.]
Pulmonary Disease, Chronic Obstructive
Gelatinolytic activity in tracheal aspirates of horses with chronic obstructive pulmonary disease.
Pulmonary Edema
[Usefulness of a protease inhibitor (urinastatin) in ARDS with infectious diseases]
Pulmonary Fibrosis
New approaches for the evaluation of pulmonary toxicity: bronchoalveolar lavage fluid analysis.
Pyelonephritis
Urine beta-glucuronidase in renal injury. II. Excretion patterns in experimental staphylococcal pyelonephritis in rats.
[Renal dipeptidylpeptidase IV excretion in drug-induced kidney changes]
Pyloric Stenosis
beta-Glucuronidase in gastric aspirate after oral cimetidine in the diagnosis of carcinoma of the stomach.
Pyoderma
Biotypes of group A streptococci isolated from children.
Transient absence of C5a-specific neutrophil function in inflammatory disorders of the skin.
Reflex, Abnormal
Juvenile neurogenic muscle atrophy with lysosomal enzyme deficiencies: new disease or variant of mucopolysaccharidosis?
Renal Insufficiency
Acid phosphatase, beta-glucuronidase and N-acetyl-beta-D-glucosaminidase activity of peritoneal neutrophils in patients with terminal renal failure treated by intermittent peritoneal dialysis.
Activity of some lysosomal enzymes in peritoneal lymphocytes from patients with terminal renal failure treated by intermittent peritoneal dialysis.
Urinary excretion of enzymes in cirrhotics with renal failure.
[Cytomorphological, cytochemical and functional characteristics of cells from peritoneal dialysate of patients with terminal renal failure treated by intermittent peritoneal dialysis. IV. Cytochemical studies of acid phosphatase, beta-glucuronidase and N-acetyl-beta-D-glucosaminidase activity]
Retinal Detachment
Lysosomal enzymes in tear fluids from patients with ocular diseases.
Lysosomal enzymes in the serum of patients with with Behçet's disease.
Progressive cone dystrophy associated with low alpha-L-fucosidase activity in serum and leukocytes.
Retinal Dystrophies
Lysosomal enzymes in tear fluids from patients with ocular diseases.
Rheumatic Diseases
[Changes in beta-glucuronidase activity in the blood cells and blood serum of patients with rheumatism in relation to clinical manifestations of the disease]
Rheumatic Fever
[Beta-glucuronidase and acid phosphatase activity in children with rheumatic fever]
[Changes in beta-glucuronidase activity in the blood cells and blood serum of patients with rheumatism in relation to clinical manifestations of the disease]
[New research on synovial enzymology]
[Zinc and enzymes in the synovial fluid and blood in various types of rheumatism]
Sarcoidosis
Hydrolytic enzyme of the alveolar macrophage in diffuse pulmonary interstitial disease.
Sarcoid reaction observed in a worker with a history of asbestos exposure.
[Acid phosphatase and beta-glucuronidase activities of lymphocytes in patients with sarcoidosis (author's transl)]
Sarcoma
Biochemical changes in tumor cells caused by antitumor agents. II. Effect of several antitumor agents in vivo and in vitro on beta-glucuronidase and two other lysosomal enzymes of Yoshida sarcoma cells.
Differences in targeting and secretion of cathepsins B and L by BALB/3T3 fibroblasts and Moloney murine sarcoma virus-transformed BALB/3T3 fibroblasts.
Gene therapy for sarcoma utilizing adenoviral transfer of the beta-glucuronidase and bax genes and an anthracyline prodrug.
Sarcoma, Avian
Development of gene expression system in a marine diatom using viral promoters of a wide variety of origin.
Sarcoma, Yoshida
Biochemical changes in tumor cells caused by antitumor agents. II. Effect of several antitumor agents in vivo and in vitro on beta-glucuronidase and two other lysosomal enzymes of Yoshida sarcoma cells.
Schistosomiasis
Biochemical studies on beta-glucuronidase in the urinary bladder of normal and Schistosoma mansoni infected mice treated with hycanthone.
Inapplicability of urinary beta-glucuronidase determination as a field test of cure of urinary bilharziasis.
Role of schistosomiasis in human bladder cancer: evidence of association, aetiological factors, and basic mechanisms of carcinogenesis.
Schistosomiasis and urinary beta-glucuronidase activity.
Scleroderma, Diffuse
Origin of the enhanced activity of lysosomal beta-galactosidase in serum and skin in progressive systemic sclerosis.
Scleroderma, Systemic
[The clinical value of determining beta-glucuronidase activity in the cells and blood serum of patients with systemic scleroderma]
Scrapie
Intraneuronal enzymic inclusions in the histological diagnosis of scrapie.
Seizures
Beta-glucuronidase in sera of patients with epileptic seizure activity, diabetes and some other disease states.
[Serum beta-glucuronidase activity in patients with epilepsy]
Sepsis
Complement activation and clearance in acute illness and injury: evidence for C5a as a cell-directed mediator of the adult respiratory distress syndrome in man.
Shock, Septic
[Effect of hydrocortisone and dopamine on activity of beta-glucuronidase in lung parenchyma during experimental septic shock]
Siderosis
[The beta-glycerophosphatase, tributyrinoesterase and beta-glucuronidase activity of the liver in experimental siderosis.]
Silicosis
Serum beta-N-acetylglucosaminidase and beta-glucuronidase activities in silicosis patients and in workers exposed to silica dust.
Serum lysosomal enzyme activities in silicosis and asbestosis.
Silicotuberculosis
Histoenzymology of the lung. II. The behaviour of lung hydrolytic enzymes during some experimental pulmonary processes.
Skin Diseases
Autosomal dominant keratoderma, ichthyosiform dermatosis and elevated serum beta-glucuronidase.
Transient absence of C5a-specific neutrophil function in inflammatory disorders of the skin.
Spondylarthritis
Synovial fluid exoglycosidases are predictors of rheumatoid arthritis and are effective in cartilage glycosaminoglycan depletion.
Starvation
Changes in gene expression in Arabidopsis shoots during phosphate starvation and the potential for developing smart plants.
Glycogen and glycogen-hydrolysing lysosomal enzyme activity in mouse liver: effects of fasting, adrenoceptor antagonism and insulin-induced hypoglycaemia.
Histochemical findings in the rat gastric mucosa during starvation.
Implications of alpha-amylase production and beta-glucuronidase expression in Escherichia coli strains.
Lysosomal enzyme activities in pancreatic islets from normal and obese hyperglycemic mice.
Promoter of Arabidopsis thaliana phosphate transporter gene drives root-specific expression of transgene in rice.
Regulation of constitutively expressed and induced cutinase genes by different zinc finger transcription factors in Fusarium solani f. sp. pisi (Nectria haematococca).
Survival of Escherichia coli in freshwater: beta-D-glucuronidase activity measurements and characterization of cellular states.
The autophagy-associated Atg8 gene family operates both under favourable growth conditions and under starvation stresses in Arabidopsis plants.
Stomach Diseases
Beta-glucuronidase activity in gastric juice in various gastric diseases.
[Activity of beta-glucuronidase in some gastric diseases]
[Beta-glucuronidase activity in various stomach diseases]
Stomach Neoplasms
A study of serum glycosidases in cancer.
Activity of some lysosomal enzymes in neutrophils from peripheral blood of patients with digestive tract cancer at different clinical stages of the disease. A cytochemical study.
beta-Glucoronidase and the gastric epithelial cell. A study using organ culture.
Beta-glucuronidase activity in gastric cancer.
Beta-glucuronidase, LDH and LDH isoenzyme levels and screening for gastric cancer.
Elevated gastric juice enzymes--a marker for increased gastric cancer risk?
Enzymatic deficiencies of the immune system cells in patients with cancer of the larynx and other malignancies.
Lysosomal enzymes in peripheral blood lymphocytes of patients with gastric cancer.
[Enzymes in gastric juice. An aid in the diagnosis of gastric cancer]
[Relationship between gastric cancer invasion and beta-glucuronidase (beta-G) and beta-N-acetyl-glucosaminidase (beta-N-AG) activities]
Stroke
[Serum beta-glucuronidase activity in early and late pregnancy toxemia and in uteroplacental apoplexy]
[Serum beta-glucuronidase activity in patients with sequelae of cerebrovascular accidents.]
Suppuration
Host mediators in endodontic exudates. I. Indicators of inflammation and humoral immunity.
Synovitis
A novel method for the sampling of synovial fluid in mice. Assay of a synovial lysosomal enzyme in zymosan-induced arthritis.
Chronic immune synovitis in rabbits. I. Immunoglobulin and beta-glucuronidase analyses of synovial tissues and joint exudates.
Tachycardia
Low beta-glucuronidase enzyme activity and mutations in the human beta-glucuronidase gene in mild mucopolysaccharidosis type VII, pseudodeficiency and a heterozygote.
Testicular Neoplasms
[Changes in beta-glucuronidase in the fluid of essential hydrocele and in hydrocele secondary to testicular neoplasms.]
Tetanus
A genetic fusion construct between the tetanus toxin C fragment and the lysosomal acid hydrolase beta-glucuronidase expresses a bifunctional protein with enhanced secretion and neuronal uptake.
Thrombocytopenia
Activation of plasma systems and blood cells by endotoxin in rabbits.
Methylprednisolone prophylaxis protects against endotoxin-induced death in rabbits.
Thyroid Diseases
Serum beta-glucuronidase in thyroid disease.
Thyrotoxicosis
Thyroid effects of amiodarone: clinical update.
Toxemia
Serum beta-glucuronidase levels during toxemia of pregnancy.
Trichomonas Infections
[Beta-glucuronidase activity in the vaginal fluid of women with trichomoniasis]
Tuberculosis
A novel peptide derivative exhibits anti inflammatory and antioxidant activity in adjuvant induced arthritis in rats.
Effect of beta-glucuronidase inhibitor from Mycobacterium tuberculosis against microbicidal activity in phagocytes of guinea pigs.
Fate of Mycobacterium tuberculosis inside rat peritoneal macrophages in vitro.
Histoenzymology of the lung. II. The behaviour of lung hydrolytic enzymes during some experimental pulmonary processes.
HLA-DR2 phenotype and plasma lysozyme, beta-glucuronidase and acid phosphatase levels in pulmonary tuberculosis.
Purification and characterization of beta-glucuronidase inhibitor from Mycobacterium tuberculosis.
[Changes of beta-glucuronidase in the blood and urine of patients with osseous tuberculosis.]
Tuberculosis, Pulmonary
HLA-DR2 phenotype and plasma lysozyme, beta-glucuronidase and acid phosphatase levels in pulmonary tuberculosis.
Impaired interleukin-8-induced degranulation of polymorphonuclear neutrophils from human immunodeficiency virus type 1-infected individuals.
[Acid phosphatase and beta-glucuronidase activities of T and B lymphocytes in patients with pulmonary tuberculosis (author's transl)]
Tularemia
Relationship of serum beta-glucuronidase and lysozyme to pathogenesis of tularemia in immune and nonimmune rats.
Sequential metabolic alterations in the myocardium during influenza and tularemia in mice.
Urinary Bladder Neoplasms
A study of urinary beta-glucuronidase activity in the production of bladder tumours in rats.
A study on the aetiological factors of bilharzial bladder cancer in Egypt. 3. Urinary beta-glucuronidase.
A study on the etiological factors of bilharzial bladder cancer in Egypt. 6. The possible role of urinary bacteria.
beta-Glucuronidase activity in the urine of patients with bladder cancer and other conditions.
Effect of a Beta-glucuronidase inhibitor and methylcholanthrene on the induction of bladder tumors in rats.
Enzyme activity in relation to cancer: inhibition of urinary beta-glucuronidase of patients with cancer of the bladder by oral administration of 1:4-saccharolactone and related compounds.
Role of urinary beta-glucuronidase in human bladder cancer.
Studies on beta-glucuronidase and DNA synthesis activities in the bladder tumors.
Studies on urinary isozymes of lactic dehydrogenase and beta-glucuronidase in patients with bladder tumors.
Sugar industry sponsorship of germ-free rodent studies linking sucrose to hyperlipidemia and cancer: An historical analysis of internal documents.
The activity of beta-glucuronidase in cases of bladder neoplasms.
The possible role of enzymes and metabolites in the genesis of bladder cancer. A study of beta-glucuronidase activity in the urine.
Tolerance test with phenolphthalein: study of its detoxication and of urinary beta-glucuronidase activity "in vivo" in patients with bladder neoplasm.
Urinary beta-glucuronidase activity in cancer of the bladder and other diseases.
Urinary glucuronidase and arylsulfatases in identical twins of bladder cancer patients.
[A new way of preventing urinary bladder tumors]
[Evaluation of the usefulness of analysis of beta-glucuronidase levels in patients with superficial cancer and papilloma of the bladder]
[Histochemical investigations on human bladder cancer (author's transl)]
[Preventive effect of beta-glucuronidase inhibitor (SLA) on recurrence of the bladder tumor]
[Studies on urinary beta-glucuronidase in patients with bladder cancer]
[Study of beta-glucuronidase activity in bladder tumors]
[The effect of added dietary beta-glucuronidase inhibitor on the occurrence of 2-acetyl-aminofluorene induced bladder tumors in rats]
Urinary Bladder, Neurogenic
[Clinical evaluation of Ubretid on neurogenic bladder dysfunction and on high serum beta-glucuronidase]
Urinary Tract Infections
Beta-D-Glucuronidase activity among prototrophic and auxotrophic variants of Escherichia coli and other Enterobacteriaceae commonly implicated in urinary tract infections.
beta-Glucuronidase activity in cerebrospinal fluid pleocytosis due to urinary tract infection.
Diagnostic potential of urinary enzymes and beta 2-microglobulin in acute urinary tract infection.
Failure of urinary beta-glucuronidase activity to localize the site of urinary tract infection.
Rapid detection of urinary tract infection caused by Escherichia coli or Proteeae species.
Rapid identification of micro-organisms from urinary tract infections by beta-glucuronidase, phenylalanine deaminase, cytochrome oxidase and indole tests on isolation media.
The value of urinary beta-glucuronidase activity in the assessment of urinary tract infections.
Urologic Diseases
Urinary beta-glucuronidase enzyme activity in some bilharzial urinary tract diseases.
Urinary beta-glucuronidase in urologic diseases of the kidneys.
Uterine Cervical Neoplasms
Beta-glucuronidase studies in women. 2. Cancer of the cervix uteri.
Beta-glucuronidase studies in women. VI. Premenopausal vaginal fluid values in relation to invasive cervical cancer.
Beta-Glucuronidase studies in women. VII. Premenopausal vaginal-fluid-beta-glucuronidase values in relation to in situ cancer of the cervix.
Comparison of vaginal and cervical beta-glucuronidase in relation to cancer of the cervix and uterus.
New observations on beta-glucuronidase in human cervical cancer.
STUDIES ON THE EFFECT OF ESTROGEN ON THE RADIOSENSITIVITY OF CERVICAL CANCER, WITH SPECIAL REFERENCE TO THE PATTERNS OF SERUM LACTIC DEHYDROGENASE AND BETA-GLUCURONIDASE.
The intracellular enzymatic response of neutrophils and lymphocytes in patients with precancerous states and cancer of the uterine cervix.
The relationship of the enzyme beta-glucuronidase to cancer of the cervix uteri.
[Beta-glucuronidase activity of the vaginal fluid in cancer of the uterine cervix.]
[Beta-glucuronidase and the stimulation of the reticuloendothelial system in cervical cancer.]
[Beta-glucuronidase in the early diagnosis of cancer of the cervix uteri]
[HISTOCHEMICAL STUDIES ON THE ACTIVITY OF BETA-GLUCURONIDASE IN CERVICAL CANCER.]
[Studies on beta-glucuronidase and its isozyme in cervical cancer of the uterus]
Uterine Neoplasms
The significance of beta-glucuronidase content in the vaginal fluid of patients with cancer of the uterus.
The significance of tissue beta-glucuronidase content in patients with cancer of the uterus.
[Studies on beta-glucuronidase and its isozyme in cervical cancer of the uterus]
Uveitis
Lysosomal enzymes in the serum of patients with with Behçet's disease.
[The role of lysosomal enzymes in adjuvant-induced uveitis in rabbits (author's transl)]
Vaccinia
E. coli beta-glucuronidase (GUS) as a marker for recombinant vaccinia viruses.
Novel oncolytic agent GLV-1h68 is effective against malignant pleural mesothelioma.
Treatment of anaplastic thyroid carcinoma in vitro with a mutant vaccinia virus.
Vaccinia virus protein synthesis has a low requirement for the intact translation initiation factor eIF4F, the cap-binding complex, within infected cells.
Vaginitis
Beta-glucuronidase studies in women. III. Trichomonas vaginalis vaginitis and vaginal fluid enzyme activity.
[Effect of vaginitis upon beta-glucuronidase activity]
Varicocele
Abnormal expression of acid glycosidases in seminal plasma and spermatozoa from infertile men with varicocele.
Varicose Veins
Lysosomal enzymes and superoxide production in polymorphonuclear leukocytes of patients with primary varicose veins.
Vascular Diseases
[Serum beta-glucuronidase activity in diabetes with and without vascular complications. I. Serum beta-glucuronidase activity in diabetic women in relation to vascular disease]
Vasculitis
A novel method for the sampling of synovial fluid in mice. Assay of a synovial lysosomal enzyme in zymosan-induced arthritis.
Vesicular Stomatitis
Infectivity of a human respiratory syncytial virus lacking the SH, G, and F proteins is efficiently mediated by the vesicular stomatitis virus G protein.
Virus Diseases
A hypersensitive response-like mechanism is involved in resistance of potato plants bearing the Ry(sto) gene to the potyviruses potato virus Y and tobacco etch virus.
Analysis of stress-induced or salicylic acid-induced expression of the pathogenesis-related 1a protein gene in transgenic tobacco.
Beta-glucuronidase release from leukocytes in children.
Identification of genes involved in replication and movement of peanut clump virus.
Vitamin A Deficiency
Histochemical studies on the salivary glands in white rats in vitamin A deficiency. I. Beta-glucuronidase and beta-galactosidase in secretory cells of the sublingual and submandibular glands.
Vitamin E Deficiency
Vitamin E deficiency and the susceptibility to lipid peroxidation of mouse cardiac and skeletal muscles.
Whooping Cough
A mechanistic approach into a diabetic serum factor-mediated release of beta-glucuronidase in normal neutrophils.
Expression and secretion of beta-glucuronidase and Pertussis toxin S1 by Streptomyces lividans.
Nucleotide-, chemotactic peptide- and phorbol ester-induced exocytosis in HL-60 leukemic cells.