Reference on EC 3.1.4.46 - glycerophosphodiester phosphodiesterase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Larson, T.J.; Ehrmann, M.; Boos, W.
Periplasmic glycerophosphodiester phosphodiesterase of Escherichia coli, a new enzyme of the glp regulon
J. Biol. Chem.
258
5428-5432
1983
Escherichia coli
Kasahara, M.; Makino, K.; Amemura, M.; Nakata, A.
Nucleotide sequence of the ugpQ gene encoding glycerophosphoryl diester phosphodiesterase of Escherichia coli K-12
Nucleic Acids Res.
17
2854
1989
Escherichia coli
Brzoska, P.; Boos, W.
Characteristics of a ugp-encoded and phoB-dependent glycerophosphoryl diester phosphodiesterase which is physically dependent on the ugp transport system of Escherichia coli
J. Bacteriol.
170
4125-4135
1988
Escherichia coli
Tommassen, J.; Eiglmeier, K.; Cole, S.T.; Overduin, P.; Larson, T.J.; Boos, W.
Characterization of two genes, glpQ and ugpQ, encoding glycerophosphoryl diester phosphodiesterases of Escherichia coli
Mol. Gen. Genet.
226
321-327
1991
Escherichia coli
Munson, R.S.; Sasaki, K.
Protein D, a putative immunoglobulin D-binding protein produced by Haemophilus influenzae, is glycerophosphodiester phosphodiesterase
J. Bacteriol.
175
4569-4571
1993
Haemophilus influenzae
Brzoskia, P.; Boos, W.
The ugp-encoded glycerophosphoryldiester phosphodiesterase, a transport-related enzyme of Escherichia coli
FEMS Microbiol. Rev.
63
115-124
1989
Escherichia coli
-
McLoughlin, S.Y.; Jackson, C.; Liu, J.W.; Ollis, D.L.
Growth of Escherichia coli coexpressing phosphotriesterase and glycerophosphodiester phosphodiesterase, using paraoxon as the sole phosphorus source
Appl. Environ. Microbiol.
70
404-412
2004
Klebsiella aerogenes
Porcella, S.F.; Raffel, S.J.; Schrumpf, M.E.; Schriefer, M.E.; Dennis, D.T.; Schwan, T.G.
Serodiagnosis of Louse-Borne relapsing fever with glycerophosphodiester phosphodiesterase (GlpQ) from Borrelia recurrentis
J. Clin. Microbiol.
38
3561-3571
2000
Borrelia recurrentis
Shevchenko, D.V.; Sellati, T.J.; Cox, D.L.; Shevchenko, O.V.; Robinson, E.J.; Radolf, J.D.
Membrane topology and cellular location of the Treponema pallidum glycerophosphodiester phosphodiesterase (GlpQ) ortholog
Infect. Immun.
67
2266-2276
1999
Treponema pallidum
Schwan, T.G.; Battisti, J.M.; Porcella, S.F.; Raffel, S.J.; Schrumpf, M.E.; Fischer, E.R.; Carroll, J.A.; Stewart, P.E.; Rosa, P.; Somerville, G.A.
Glycerol-3-phosphate acquisition in spirochetes: distribution and biological activity of glycerophosphodiester phosphodiesterase (GlpQ) among Borrelia species
J. Bacteriol.
185
1346-1356
2003
Borrelia hermsii, Borrelia sp.
Van Der Rest, B.; Rolland, N.; Boisson, A.M.; Ferro, M.; Bligny, R.; Douce, R.
Identification and characterisation of plant glycerophosphodiester phosphodiesterase
Biochem. J.
379
601-607
2004
Daucus carota, Arabidopsis thaliana (Q9C907), Arabidopsis thaliana
Van der Rest, B.; Boisson, A.M.; Gout, E.; Bligny, R.; Douce, R.
Glycerophosphocholine metabolism in higher plant cells. Evidence of a new glyceryl-phosphodiester phosphodiesterase
Plant Physiol.
130
244-255
2002
Daucus carota
Yanaka, N.; Imai, Y.; Kawai, E.; Akatsuka, H.; Wakimoto, K.; Nogusa, Y.; Kato, N.; Chiba, H.; Kotani, E.; Omori, K.; Sakurai, N.
Novel membrane protein containing glycerophosphodiester phosphodiesterase motif is transiently expressed during osteoblast differentiation
J. Biol. Chem.
278
43595-43602
2003
Homo sapiens (Q9HCC8), Mus musculus (Q640M6), Mus musculus
Nogusa, Y.; Fujioka, Y.; Komatsu, R.; Kato, N.; Yanaka, N.
Isolation and characterization of two serpentine membrane proteins containing glycerophosphodiester phosphodiesterase, GDE2 and GDE6
Gene
337
173-179
2004
Mus musculus (Q640M6), Mus musculus
Fernandez-Murray, J.P.; McMaster, C.R.
Glycerophosphocholine catabolism as a new route for choline formation for phosphatidylcholine synthesis by the Kennedy pathway
J. Biol. Chem.
280
38290-38296
2005
Saccharomyces cerevisiae
Bacon, R.M.; Pilgard, M.A.; Johnson, B.J.; Raffel, S.J.; Schwan, T.G.
Glycerophosphodiester phosphodiesterase gene (glpQ) of Borrelia lonestari identified as a target for differentiating Borrelia species associated with hard ticks (Acari:Ixodidae)
J. Clin. Microbiol.
42
2326-2328
2004
Borrelia miyamotoi (Q6UK58), Borrelia lonestari (Q6UK59), Borrelia lonestari, Borrelia miyamotoi FR64B (Q6UK58)
Santelli, E.; Schwarzenbacher, R.; McMullan, D.; Biorac, T.; Brinen, L.S.; Canaves, J.M.; Cambell, J.; Dai, X.; Deacon, A.M.; Elsliger, M.A.; et.al.
Crystal structure of a glycerophosphodiester phosphodiesterase from Thermotoga maritima (TM1621) at 1.60 A resolution
Proteins
56
167-170
2004
Thermotoga maritima (Q9X1V6), Thermotoga maritima, Thermotoga maritima DSM 3109 (Q9X1V6)
Jackson, C.J.; Carr, P.D.; Kim, H.K.; Liu, J.W.; Ollis, D.L.
The purification, crystallization and preliminary diffraction of a glycerophosphodiesterase from Enterobacter aerogenes
Acta Crystallogr. Sect. F
62
659-661
2006
Klebsiella aerogenes (Q6XBH1)
Halperin, T.; Orr, N.; Cohen, R.; Hasin, T.; Davidovitch, N.; Klement, E.; Kayouf, R.; Baneth, G.; Cohen, D.; Yavzori, M.
Detection of relapsing fever in human blood samples from Israel using PCR targeting the glycerophosphodiester phosphodiesterase (GlpQ) gene
Acta Trop.
98
189-195
2006
Borrelia persica (Q1EGY6), Borrelia persica
Patton-Vogt, J.
Transport and metabolism of glycerophosphodiesters produced through phospholipid deacylation
Biochim. Biophys. Acta
1771
337-342
2007
Saccharomyces cerevisiae
Yanaka, N.
Mammalian glycerophosphodiester phosphodiesterases
Biosci. Biotechnol. Biochem.
71
1811-1818
2007
Haemophilus influenzae, Escherichia coli (P09394), Escherichia coli (P10908)
Yanaka, N.; Nogusa, Y.; Fujioka, Y.; Yamashita, Y.; Kato, N.
Involvement of membrane protein GDE2 in retinoic acid-induced neurite formation in Neuro2A cells
FEBS Lett.
581
712-718
2007
Mus musculus
Ohshima, N.; Yamashita, S.; Takahashi, N.; Kuroishi, C.; Shiro, Y.; Takio, K.
Escherichia coli cytosolic glycerophosphodiester phosphodiesterase (UgpQ) requires Mg2+, Co2+, or Mn2+ for its enzyme activity
J. Bacteriol.
190
1219-1223
2008
Escherichia coli K-12, Escherichia coli (P09394), Escherichia coli (P10908), Escherichia coli
Lang, Q.; Zhang, H.; Li, J.; Yin, H.; Zhang, Y.; Tang, W.; Wan, B.; Yu, L.
Cloning and characterization of a human GDPD domain-containing protein GDPD5
Mol. Biol. Rep.
35
351-359
2007
Homo sapiens (Q8WTR4), Homo sapiens
Rao, K.N.; Bonanno, J.B.; Burley, S.K.; Swaminathan, S.
Crystal structure of glycerophosphodiester phosphodiesterase from Agrobacterium tumefaciens by SAD with a large asymmetric unit
Proteins Struct. Funct. Bioinform.
65
514-518
2006
Agrobacterium tumefaciens
Toropainen, M.; Raitolehto, A.; Henckaerts, I.; Wauters, D.; Poolman, J.; Lestrate, P.; Kaeyhty, H.
Pneumococcal Haemophilus influenzae protein D conjugate vaccine induces antibodies that inhibit glycerophosphodiester phosphodiesterase activity of protein D
Infect. Immun.
76
4546-4553
2008
Haemophilus influenzae
Chang, P.A.; Shao, H.B.; Long, D.X.; Sun, Q.; Wu, Y.J.
Isolation, characterization and molecular 3D model of human GDE4, a novel membrane protein containing glycerophosphodiester phosphodiesterase domain
Mol. Membr. Biol.
25
557-566
2008
Homo sapiens (Q8N9F7), Homo sapiens
Shi, L.; Liu, J.F.; An, X.M.; Liang, D.C.
Crystal structure of glycerophosphodiester phosphodiesterase (GDPD) from Thermoanaerobacter tengcongensis, a metal ion-dependent enzyme: insight into the catalytic mechanism
Proteins
72
280-288
2008
Caldanaerobacter subterraneus subsp. tengcongensis (Q8RB32), Caldanaerobacter subterraneus subsp. tengcongensis
Jackson, C.J.; Hadler, K.S.; Carr, P.D.; Oakley, A.J.; Yip, S.; Schenk, G.; Ollis, D.L.
Malonate-bound structure of the glycerophosphodiesterase from Enterobacter aerogenes (GpdQ) and characterization of the native Fe2+ metal-ion preference
Acta Crystallogr. Sect. F
64
681-685
2008
Klebsiella aerogenes (Q6XBH1)
Hadler, K.S.; Mitic, N.; Yip, S.H.; Gahan, L.R.; Ollis, D.L.; Schenk, G.; Larrabee, J.A.
Electronic structure analysis of the dinuclear metal center in the bioremediator glycerophosphodiesterase (GpdQ) from Enterobacter aerogenes
Inorg. Chem.
49
2727-2734
2010
Klebsiella aerogenes (Q6XBH1)
Hadler, K.S.; Tanifum, E.A.; Yip, S.H.; Mitic, N.; Guddat, L.W.; Jackson, C.J.; Gahan, L.R.; Nguyen, K.; Carr, P.D.; Ollis, D.L.; Hengge, A.C.; Larrabee, J.A.; Schenk, G.
Substrate-promoted formation of a catalytically competent binuclear center and regulation of reactivity in a glycerophosphodiesterase from Enterobacter aerogenes
J. Am. Chem. Soc.
130
14129-14138
2008
Klebsiella aerogenes (Q6XBH1)
Hadler, K.S.; Gahan, L.R.; Ollis, D.L.; Schenk, G.
The bioremediator glycerophosphodiesterase employs a non-processive mechanism for hydrolysis
J. Inorg. Biochem.
104
211-213
2010
Klebsiella aerogenes
Santos-Beneit, F.; Rodriguez-Garcia, A.; Apel, A.K.; Martin, J.F.
Phosphate and carbon source regulation of two PhoP-dependent glycerophosphodiester phosphodiesterase genes of Streptomyces coelicolor
Microbiology
155
1800-1811
2009
Streptomyces coelicolor (Q8CJI8), Streptomyces coelicolor (Q93JJ3), Streptomyces coelicolor
Johnson, R.W.; McGillivary, G.; Denoel, P.; Poolman, J.; Bakaletz, L.O.
Abrogation of nontypeable Haemophilus influenzae protein D function reduces phosphorylcholine decoration, adherence to airway epithelial cells, and fitness in a chinchilla model of otitis media
Vaccine
29
1211-1221
2011
Haemophilus influenzae, Haemophilus influenzae 86-028NP
Corda, D.; Mosca, M.; Ohshima, N.; Grauso, L.; Yanaka, N.; Mariggio, S.
The emerging physiological roles of the glycerophosphodiesterase family
FEBS J.
281
998-1016
2014
Klebsiella aerogenes, Agrobacterium tumefaciens, Arabidopsis thaliana, Bacillus pumilus, Saccharomyces cerevisiae, Saccharomyces cerevisiae (Q02979), Lupinus albus, Mus musculus, Musca domestica, Plasmodium falciparum, Rattus norvegicus, Streptomyces coelicolor, Thermotoga maritima, Caldanaerobacter subterraneus subsp. tengcongensis, Mycoplasma hyorhinis (E0TL71), Treponema pallidum (O30405), Escherichia coli (P09394), Escherichia coli (P10908), Bacillus subtilis (P54527), Mycoplasma pneumoniae (P75367), Haemophilus influenzae (Q06282), Borrelia hermsii (Q45201), Pasteurella multocida (Q79LP3), Homo sapiens (Q8WTR4), Homo sapiens (Q9NPB8), Staphylococcus aureus (Q99387), Bacillus pumilus DSM 27, Haemophilus influenzae DSM 11121 (Q06282)
Cao, M.D.; Doepkens, M.; Krishnamachary, B.; Vesuna, F.; Gadiya, M.M.; Loenning, P.E.; Bhujwalla, Z.M.; Gribbestad, I.S.; Glunde, K.
Glycerophosphodiester phosphodiesterase domain containing 5 (GDPD5) expression correlates with malignant choline phospholipid metabolite profiles in human breast cancer
NMR Biomed.
25
1033-1042
2012
Homo sapiens (Q8WTR4)
Pedroso, M.M.; Ely, F.; Carpenter, M.C.; Mitic, N.; Gahan, L.R.; Ollis, D.L.; Wilcox, D.E.; Schenk, G.
Mechanistic insight from calorimetric measurements of the assembly of the binuclear metal active site of glycerophosphodiesterase (GpdQ) from Enterobacter aerogenes
Biochemistry
56
3328-3336
2017
Klebsiella aerogenes
Wang, F.; Lai, L.; Liu, Y.; Yang, B.; Wang, Y.
Expression and characterization of a novel glycerophosphodiester phosphodiesterase from Pyrococcus furiosus DSM 3638 that possesses lysophospholipase D activity
Int. J. Mol. Sci.
17
831
2016
Pyrococcus furiosus (Q8TZI9)
Cornelissen, A.; Sadovskaya, I.; Vinogradov, E.; Blangy, S.; Spinelli, S.; Casey, E.; Mahony, J.; Noben, J.P.; Dal Bello, F.; Cambillau, C.; van Sinderen, D.
The baseplate of Lactobacillus delbrueckii bacteriophage Ld17 harbors a glycerophosphodiesterase
J. Biol. Chem.
291
16816-16827
2016
Lactobacillus delbrueckii bacteriophage Ld17
Mehra, P.; Pandey, B.K.; Verma, L.; Giri, J.
A novel glycerophosphodiester phosphodiesterase improves phosphate deficiency tolerance in rice
Plant Cell Environ.
42
1167-1179
2018
Oryza sativa
Mehra, P.; Giri, J.
Rice and chickpea GDPDs are preferentially influenced by low phosphate and CaGDPD1 encodes an active glycerophosphodiester phosphodiesterase enzyme
Plant Cell Rep.
35
1699-1717
2016
Cicer arietinum (A0A1S2XQM1), Cicer arietinum
Lidbury, I.D.E.A.; Murphy, A.R.J.; Fraser, T.D.; Bending, G.D.; Jones, A.M.E.; Moore, J.D.; Goodall, A.; Tibbett, M.; Hammond, J.P.; Scanlan, D.J.; Wellington, E.M.H.
Identification of extracellular glycerophosphodiesterases in Pseudomonas and their role in soil organic phosphorus remineralisation
Sci. Rep.
7
2179
2017
Pseudomonas stutzeri, Pseudomonas fluorescens (C3JZ29), Pseudomonas fluorescens SBW25 (C3JZ29), Pseudomonas stutzeri DSM 4166
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