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Information on EC 3.1.4.45 - N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase

for references in articles please use BRENDA:EC3.1.4.45
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IUBMB Comments
Acts on a variety of compounds in which N-acetyl-D-glucosamine is alpha-linked to a phosphate group, including the biosynthetic intermediates of the high mannose oligosaccharide components of some lysosomal enzymes and the products of EC 2.7.8.17 UDP-N-acetylglucosamine---lysosomal-enzyme N-acetylglucosaminephosphotransferase.
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The expected taxonomic range for this enzyme is: Bacteria, Eukaryota
Synonyms
2-acetamido-2-deoxy-alpha-D-glucose 1-phosphodiester acetamidodeoxyglucohydrolase, alpha-N-acetyl-D-glucosamine-1-phosphodiester acetamidodeoxyglucohydrolase, alpha-N-acetyl-D-glucosamine-1-phosphodiester N-acetylglucosaminidase, alpha-N-acetylglucosaminyl phosphodiesterase, alpha-N-acetylglucosaminylphosphodiesterase, BACOVA_00430, GH89, GlcNAc-1-phosphodiester alpha-N-acetylglucosaminidase, GlcNAc-1-phosphodiester-N-acetylglucosaminidase, lysosomal alpha-N-acetyl-glucosaminidase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
glycoprotein N-acetyl-D-glucosaminyl-phospho-D-mannose + H2O = N-acetyl-D-glucosamine + glycoprotein phospho-D-mannose
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