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Information on EC 3.1.3.57 - inositol-1,4-bisphosphate 1-phosphatase

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EC Tree
     3 Hydrolases
         3.1 Acting on ester bonds
             3.1.3 Phosphoric-monoester hydrolases
                3.1.3.57 inositol-1,4-bisphosphate 1-phosphatase
IUBMB Comments
The enzyme acts on inositol 1,4-bisphosphate and inositol 1,3,4-trisphosphate (forming inositol 3,4-bisphosphate) with similar Vmax values for both substrates, but with a five-times higher affinity for the bisphosphate. Does not act on inositol 1-phosphate, inositol 1,4,5-trisphosphate or inositol 1,3,4,5-tetrakisphosphate.
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Word Map
The enzyme appears in viruses and cellular organisms
Synonyms
inositol polyphosphate 1-phosphatase, inositol polyphosphate-1-phosphatase, inositol-1,4-bisphosphate 1-phosphatase, inositol-polyphosphate 1-phosphatase, INPP, IPP, IPPase, phosphatase, inositol 1,4-bisphosphate 1-, RnPIP, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
1D-myo-inositol 1,4-bisphosphate + H2O = 1D-myo-inositol 4-phosphate + phosphate
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