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Information on EC 3.1.1.90 - all-trans-retinyl ester 13-cis isomerohydrolase

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IUBMB Comments
All-trans-retinyl esters, which are a storage form of vitamin A, are generated by the activity of EC 2.3.1.135, phosphatidylcholine---retinol O-acyltransferase (LRAT). They can be hydrolysed to 11-cis-retinol by EC 3.1.1.64, retinoid isomerohydrolase (RPE65), or to 13-cis-retinol by this enzyme.
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The enzyme appears in viruses and cellular organisms
Synonyms
13-cis isomerohydrolase, 13-cis retinoid-specific isomerohydrolase, 13-cis-isomerohydrolase, 13-cis-specific isomerohydrolase, 13cIMH, isomerohydrolase, Rpe65, RPE65b, RPE65c, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
an all-trans-retinyl ester + H2O = 13-cis-retinol + a fatty acid
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