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Information on EC 3.1.1.89 - protein phosphatase methylesterase-1

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EC Tree
     3 Hydrolases
         3.1 Acting on ester bonds
             3.1.1 Carboxylic-ester hydrolases
                3.1.1.89 protein phosphatase methylesterase-1
IUBMB Comments
A key regulator of protein phosphatase 2A. The methyl ester is formed by EC 2.1.1.233 (leucine carboxy methyltransferase-1). Occurs mainly in the nucleus.
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Word Map
The enzyme appears in viruses and cellular organisms
Reaction Schemes
[phosphatase 2A protein]-leucine methyl ester
+
=
[phosphatase 2A protein]-leucine
+
Synonyms
phosphatase methylesterase-1, PME-1, PME1, PP2A methylesterase, PPE1, PPME1, protein phosphatase methyl-esterase PME-1, protein phosphatase methylesterase-1, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
[phosphatase 2A protein]-leucine methyl ester + H2O = [phosphatase 2A protein]-leucine + methanol
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