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Reference on EC 3.1.1.47 - 1-alkyl-2-acetylglycerophosphocholine esterase

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Blank, M.L.; Lee, T.; Fitzgerald, V.; Snyder, F.
A specific acetylhydrolase for 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine (a hypotensive and platelet-activating lipid)
J. Biol. Chem.
256
175-178
1981
Rattus norvegicus
Manually annotated by BRENDA team
Stafforini, D.M.; Rollins, E.N.; Prescott, S.M.; McIntyre, T.M.
The platelet-activating factor acetylhydrolase from human erythrocytes. Purification and properties
J. Biol. Chem.
268
3857-3865
1993
Homo sapiens
Manually annotated by BRENDA team
Hattori, M.; Inoue, K.
Purification and characterization of bovine brain platelet-activating factor acetylhydrolase
J. Biol. Chem.
268
18748-18753
1993
Bos taurus
Manually annotated by BRENDA team
Jarvi, K.; Langlais, J.; Gagnon, C.; Roberts, K.D.
Platelet-activating factor acetylhydrolase in the male reproductive tract: origin and properties
Int. J. Androl.
16
121-127
1993
Homo sapiens
Manually annotated by BRENDA team
Tsaoussis, V.; Vakirtzi-Lemonias, C.
The mouse plasma PAF acetylhydrolase: I. Characterization and properties
J. Lipid Mediat. Cell Signal.
9
301-315
1994
Mus musculus
Manually annotated by BRENDA team
Karasawa, K.; Yato, M.; Setaka, M.; Nojima, S.
Purification and characterization of platelet-activating factor acetylhydrolase from peritoneal fluid obtained from guinea pigs after endotoxin shock
J. Biochem.
116
374-379
1994
Cavia porcellus
Manually annotated by BRENDA team
Yamada, Y.; Stafforini, D.M.; Imaizumi, T.A.; Zimmermann, G.A.; McIntyre, T.M.; Prescott, S.M.
Characterization of the platelet-activating factor acetylhydrolase from human plasma by heterologous expression in Xenopus laevis oocytes
Proc. Natl. Acad. Sci. USA
91
10320-10324
1994
Homo sapiens
Manually annotated by BRENDA team
Hattori, K.; Hattori, M.; Adachi, H.; Tsujimoto, M.; Arai, H.; Inoue, K.
Purification and characterization of platelet-activating factor acetylhydrolase II from bovine liver cytosol
J. Biol. Chem.
270
22308-22313
1995
Bos taurus
Manually annotated by BRENDA team
Hough, S.R.; Parks, J.E.
Partial purification and localization of platelet-activating factor acetylhydrolase from bovine seminal plasma
J. Androl.
18
540-548
1997
Bos taurus
Manually annotated by BRENDA team
Tselepis, A.D.; Dentan, C.; Karabina, S.A.P.; Chapman, M.J.; Ninio, E.
PAF-degrading acetylhydrolase is preferentially associated with dense LDL and VHDL-1 in human plasma. Catalytic characteristics and relation to the monocyte-derived enzyme
Arterioscler. Thromb. Vasc. Biol.
15
1764-1773
1995
Homo sapiens
Manually annotated by BRENDA team
Tjoelker, L.W.; Wilder, C.; Eberhardt, C.; Stafforini, D.M.; Dietsch, G.; Schimpf, B.; Hooper, S.; Le Tong, H.; Cousens, L.S.; Zimmerman, G.A.; Yamada, Y.; McIntyre, T.M.; Prescott, S.M.; Gray, P.W.
Anti-inflammatory properties of a platelet-activating factor acetylhydrolase [see comments
Nature
374
549-553
1995
Homo sapiens
Manually annotated by BRENDA team
Grigg, M.E.; Gounaris, K.; Selkirk, M.E.
Characterization of a platelet-activating factor acetylhydrolase secreted by the nematode parasite Nippostrongylus brasiliensis
Biochem. J.
317
541-547
1996
Nippostrongylus brasiliensis
Manually annotated by BRENDA team
Karasawa, K.; Kuge, O.; Kawasaki, K.; Nishijima, M.; Nakano, Y.; Tomita, M.; Yokoyama, K.; Setaka, M.; Nojima, S.
Cloning, expression and characterization of plasma platelet-activating factor-acetylhydrolase from guinea pig
J. Biochem.
120
838-844
1996
Cavia porcellus
Manually annotated by BRENDA team
Triggiani, M.; De Marino, V.; Sofia, M.; Faraone, S.; Ambrosio, G.; Carratu, L.; Marone, G.
Characterization of platelet-activating factor acetylhydrolase in human bronchoalveolar lavage
Am. J. Respir. Crit. Care Med.
156
94-100
1997
Homo sapiens
Manually annotated by BRENDA team
Svetlov, S.; Howard, K.M.; Debuysere, M.S.; Olson, M.S.
Secretory PAF-acetylhydrolase of the rat hepatobiliary system: characterization and partial purification
Am. J. Physiol.
274
G891-G900
1998
Rattus norvegicus
Manually annotated by BRENDA team
Tew, D.G.; Boyd, H.F.; Ashman, S.A.; Theobald, C.; Leach, C.A.
Mechanism of inhibition of LDL phospholipase A2 by monocyclic-beta-lactams. Burst kinetics and the effect of stereochemistry
Biochemistry
1998
10087-10093
1998
Homo sapiens
-
Manually annotated by BRENDA team
Maya, H.; Aoki, J.; Kato, H.; Ishii, J.; Hino, S.; Arai, H.; Inoue, K.
Biochemical characterization of various catalytic complexes of the brain platelet-activating factor acetylhydrolase
J. Biol. Chem.
274
31827-31832
1999
Bos taurus
Manually annotated by BRENDA team
Stafforini, D.M.; Prescott, S.M.; McIntyre, T.M.
Human plasma platelet-activating factor acetylhydrolase. Purification and properties
J. Biol. Chem.
262
4223-4230
1987
Homo sapiens
Manually annotated by BRENDA team
Moon, T.C.; Kim, M.S.; Lee, S.J.; Lee, T.Y.; Kwon, S.H.; Baek, S.H.; Chang, H.W.
Detection and characterization of 45 kDa platelet activating factor acetylhydrolase in cerebrospinal fluid of children with meningitis
Arch. Pharm. Res.
26
554-558
2003
Homo sapiens
Manually annotated by BRENDA team
Tsoukatos, D.C.; Liapikos, T.A.; Tselepis, A.D.; Chapman, M.J.; Ninio, E.
Platelet-activating factor acetylhydrolase and transacetylase activities in human plasma low-density lipoprotein
Biochem. J.
357
457-464
2001
Homo sapiens
Manually annotated by BRENDA team
Eisaf, M.; Tselepis, A.D.
Effect of hypolipidemic drugs on lipoprotein-associated platelet activating factor acetylhydrolase. Implication for atherosclerosis
Biochem. Pharmacol.
66
2069-2073
2003
Homo sapiens
Manually annotated by BRENDA team
Min, J.H.; Wilder, C.; Aoki, J.; Arai, H.; Inoue, K.; Paul, L.; Gelb, M.H.
Platelet-activating factor acetylhydrolases: broad substrate specificity and lipoprotein binding does not modulate the catalytic properties of the plasma enzyme
Biochemistry
40
4539-4549
2001
Homo sapiens, Physarum sp.
Manually annotated by BRENDA team
Tjoelker, L.W.; Stafforini, D.M.
Platelet-activating factor acetylhydrolases in health and disease
Biochim. Biophys. Acta
1488
102-123
2000
Oryctolagus cuniculus, Cricetinae, Homo sapiens, Mus musculus, Rattus norvegicus
Manually annotated by BRENDA team
Jehle, R.; Schlame, M.; Buttner, C.; Frey, B.; Sinha, P.; Rustow, B.
Platelet-activating factor (PAF)-acetylhydrolase and PAF-like compounds in the lung: effects of hyperoxia
Biochim. Biophys. Acta
1532
60-66
2001
Rattus norvegicus
Manually annotated by BRENDA team
Yasuda, K.; Okumura, T.; Okada, H.; Nakajima, T.; Aoki, J.; Arai, H.; Inoue, K.; Nishizawa, M.; Ito, S.; Kanzaki, H.
Platelet-activating factor acetylhydrolase isoforms I and II in human uterus. Comparisons with pregnant uterus and myoma
Biol. Reprod.
64
339-344
2001
Homo sapiens
Manually annotated by BRENDA team
Biancone, L.; Cantaluppi, V.; Del Sorbo, L.; Russo, S.; Tjoelker, L.W.; Camussi, G.
Platelet-activating factor inactivation by local expression of platelet-activating factor acetyl-hydrolase modifies tumor vascularization and growth
Clin. Cancer Res.
9
4214-4220
2003
Homo sapiens, Mus musculus
Manually annotated by BRENDA team
Caslake, M.J.; Packard, C.J.
Lipoprotein-associated phospholipase A2 (platelet-activating factor acetylhydrolase) and cardiovascular disease
Curr. Opin. Lipidol.
14
347-352
2003
Homo sapiens
Manually annotated by BRENDA team
Arai, H.; Koizumi, H.; Aoki, J.; Inoue, K.
Platelet-activating factor acetylhydrolase (PAF-AH)
J. Biochem.
131
635-640
2002
Bos taurus, Homo sapiens, Mus musculus, Rattus norvegicus
Manually annotated by BRENDA team
Howard, K.M.; Olson, M.S.
The expression and localization of plasma platelet-activating factor acetylhydrolase in endotoxemic rats
J. Biol. Chem.
275
19891-19896
2000
Rattus norvegicus
Manually annotated by BRENDA team
Bae, K.; Longobardi, L.; Karasawa, K.; Malone, B.; Inoue, T.; Aoki, J.; Arai, H.; Inoue, K.; Lee, T.
Platelet-activating factor (PAF)-dependent transacetylase and its relationship with PAF acetylhydrolases
J. Biol. Chem.
275
26704-26709
2000
Rattus norvegicus
Manually annotated by BRENDA team
Serban, M.; Tanaseanu, C.; Kosaka, T.; Vidulescu, C.; Stoian, I.; Marta, D.S.; Tanaseanu, S.; Moldoveanu, E.
Significance of platelet-activating factor acetylhydrolase in patients with non-insulin-dependent (type 2) diabetes mellitus
J. Cell. Mol. Med.
6
643-647
2002
Homo sapiens
Manually annotated by BRENDA team
Al-Darmaki, S.; Schenkein, H.A.; Tew, J.G.; Barbour, S.E.
Differential expression of platelet-activating factor acetylhydrolase in macrophages and monocyte-derived dendritic cells
J. Immunol.
170
167-173
2003
Homo sapiens
Manually annotated by BRENDA team
Marques, M.; Pei, Y.; Southall, M.D.; Johnston, J.M.; Arai, H.; Aoki, J.; Inoue, T.; Seltmann, H.; Zouboulis, C.C.; Travers, J.B.
Identification of platelet-activating factor acetylhydrolase II in human skin
J. Invest. Dermatol.
119
913-919
2002
Homo sapiens
Manually annotated by BRENDA team
Tsimihodimos, V.; Karabina, S.A.; Tambaki, A.P.; Bairaktari, E.; Miltiadous, G.; Goudevenos, J.A.; Cariolou, M.A.; Chapman, M.J.; Tselepis, A.D.; Elisaf, M.
Altered distribution of platelet-activating factor-acetylhydrolase activity between LDL and HDL as a function of the severity of hypercholesterolemia
J. Lipid Res.
43
256-263
2002
Homo sapiens
Manually annotated by BRENDA team
Chroni, A.; Mavri-Vavayanni, M.
Characterization of a platelet activating factor acetylhydrolase from rat adipocyte
Life Sci.
67
2807-2825
2000
Rattus norvegicus
Manually annotated by BRENDA team
Karasawa, K.; Harada, A.; Satoh, N.; Inoue, K.; Setaka, M.
Plasma platelet activating factor-acetylhydrolase (PAF-AH)
Prog. Lipid Res.
42
93-114
2003
Cavia porcellus, Homo sapiens
Manually annotated by BRENDA team
Tiemann, U.; Tomek, W.; Schneider, F.; Wollenhaupt, K.; Kanitz, W.; Becker, F.; Pohland, R.; Alm, H.
Platelet-activating factor (PAF)-like activity, localization of PAF receptor (PAF-R) and PAF-acetylhydrolase (PAF-AH) activity in bovine endometrium at different stages of the estrous cycle and early pregnancy
Prostaglandins
65
125-141
2001
Bos taurus
Manually annotated by BRENDA team
McMullen, T.W.; Li, J.; Sheffield, P.J.; Aoki, J.; Martin, T.W.; Arai, H.; Inoue, K.; Derewenda, Z.S.
The functional implications of the dimerization of the catalytic subunits of the mammalian brain platelet-activating factor acetylhydrolase (Ib)
Protein Eng.
13
865-871
2000
Bos taurus
Manually annotated by BRENDA team
Sheffield, P.J.; McMullen, T.W.; Li, J.; Ho, Y.S.; Garrard, S.M.; Derewenda, U.; Derewenda, Z.S.
Preparation and crystal structure of the recombinant alpha(1)/alpha(2) catalytic heterodimer of bovine brain platelet-activating factor acetylhydrolase Ib
Protein Eng.
14
513-519
2001
Bos taurus (Q29460), Bos taurus
Manually annotated by BRENDA team
Sumita, C.; Maeda, M.; Fujio, Y.; Kim, J.; Fujitsu, J.; Kasayama, S.; Yamamoto, I.; Azuma, J.
Pioglitazone induces plasma platelet activating factor-acetylhydrolase and inhibits platelet activating factor-mediated cytoskeletal reorganization in macrophage
Biochim. Biophys. Acta
1673
115-121
2004
Homo sapiens
Manually annotated by BRENDA team
Lee, E.; Lee, S.J.; Lee, T.Y.; Chang, H.W.
cDNA cloning and expression of biologically active platelet activating factor-acetylhydrolase (PAF-AH) from bovine mammary gland
Biol. Pharm. Bull.
28
580-583
2005
Bos taurus
Manually annotated by BRENDA team
Nakos, G.; Kitsiouli, E.; Hatzidaki, E.; Koulouras, V.; Touqui, L.; Lekka, M.E.
Phospholipases A2 and platelet-activating-factor acetylhydrolase in patients with acute respiratory distress syndrome
Crit. Care Med.
33
772-779
2005
Homo sapiens
Manually annotated by BRENDA team
Karasawa, K.; Shirakura, M.; Harada, A.; Satoh, N.; Yokoyama, K.; Setaka, M.; Inoue, K.
Red blood cells highly express type I platelet-activating factor-acetylhydrolase (PAF-AH) which consists of the alpha1/alpha2 complex
J. Biochem.
138
509-517
2005
Sus scrofa
Manually annotated by BRENDA team
Bonin, F.; Ryan, S.D.; Migahed, L.; Mo, F.; Lallier, J.; Franks, D.J.; Arai, H.; Bennett, S.A.
Anti-apoptotic actions of the platelet-activating factor acetylhydrolase I alpha2 catalytic subunit
J. Biol. Chem.
279
52425-52436
2004
Rattus norvegicus (P83006)
Manually annotated by BRENDA team
Stafforini, D.M.; Sheller, J.R.; Blackwell, T.S.; Sapirstein, A.; Yull, F.E.; McIntyre, T.M.; Bonventre, J.V.; Prescott, S.M.; Roberts, L.J.2nd.
Release of free F2-isoprostanes from esterified phospholipids is catalyzed by intracellular and plasma platelet-activating factor acetylhydrolases
J. Biol. Chem.
281
4616-4623
2006
Homo sapiens
Manually annotated by BRENDA team
Ishihara, M.; Iwasaki, T.; Nagano, M.; Ishii, J.; Takano, M.; Kujiraoka, T.; Tsuji, M.; Hattori, H.; Emi, M.
Functional impairment of two novel mutations detected in lipoprotein-associated phospholipase A2 (Lp-PLA2) deficiency patients
J. Hum. Genet.
49
302-307
2004
Homo sapiens
Manually annotated by BRENDA team
Vinson, S.M.; Rickard, A.; Ryerse, J.S.; McHowat, J.
Neutrophil adherence to bladder microvascular endothelial cells following platelet-activating factor acetylhydrolase inhibition
J. Pharmacol. Exp. Ther.
314
1241-1247
2005
Homo sapiens
Manually annotated by BRENDA team
Papavasiliou, E.C.; Gouva, C.; Siamopoulos, K.C.; Tselepis, A.D.
Erythrocyte PAF-acetylhydrolase activity in various stages of chronic kidney disease: effect of long-term therapy with erythropoietin
Kidney Int.
68
246-255
2005
Homo sapiens
Manually annotated by BRENDA team
Inoue, T.; Sugimoto, A.; Suzuki, Y.; Yamamoto, M.; Tsujimoto, M.; Inoue, K.; Aoki, J.; Arai, H.
Type II platelet-activating factor-acetylhydrolase is essential for epithelial morphogenesis in Caenorhabditis elegans
Proc. Natl. Acad. Sci. USA
101
13233-13238
2004
Caenorhabditis elegans, Caenorhabditis elegans (Q22943)
Manually annotated by BRENDA team
Rizos, E.; Tambaki, A.P.; Gazi, I.; Tselepis, A.D.; Elisaf, M.
Lipoprotein-associated PAF-acetylhydrolase activity in subjects with the metabolic syndrome
Prostaglandins Leukot. Essent. Fatty Acids
72
203-209
2005
Homo sapiens
Manually annotated by BRENDA team
Quistad, G.B.; Fisher, K.J.; Owen, S.C.; Klintenberg, R.; Casida, J.E.
Platelet-activating factor acetylhydrolase: selective inhibition by potent n-alkyl methylphosphonofluoridates
Toxicol. Appl. Pharmacol.
205
149-156
2005
Homo sapiens, Mus musculus
Manually annotated by BRENDA team
Mitsios, J.V.; Vini, M.P.; Stengel, D.; Ninio, E.; Tselepis, A.D.
Human platelets secrete the plasma type of platelet-activating factor acetylhydrolase primarily associated with microparticles
Arterioscler. Thromb. Vasc. Biol.
26
1907-1913
2006
Homo sapiens
Manually annotated by BRENDA team
Karabina, S.; Ninio, E.
Plasma PAF-acetylhydrolase: An unfulfilled promise?
Biochim. Biophys. Acta
1761
1351-1358
2006
Homo sapiens
Manually annotated by BRENDA team
Karasawa, K.
Clinical aspects of plasma platelet-activating factor-acetylhydrolase
Biochim. Biophys. Acta
1761
1359-1372
2006
Homo sapiens
Manually annotated by BRENDA team
Moon, T.C.; Son, S.Y.; Chang, H.W.
Purification and characterization of 45 kDa PAF acetylhydrolase from bovine colostrum
Biol. Pharm. Bull.
30
1668-1673
2007
Bos taurus (Q29460 and P68401), Bos taurus
Manually annotated by BRENDA team
Seo, H.S.; Kim, J.H.; Nahm, M.H.
Platelet-activating factor-acetylhydrolase can monodeacylate and inactivate lipoteichoic acid
Clin. Vaccine Immunol.
13
452-458
2006
Homo sapiens
Manually annotated by BRENDA team
Grypioti, A.D.; Mykoniatis, M.; Demopoulos, C.A.; Kostopanagiotou, G.
Recombinant platelet-activating factor-acetylhydrolase attenuates paracetamol-induced liver oxidative stress, injury, and regeneration
Digest. Dis. Sci.
52
192-199
2007
Rattus norvegicus (O35264 and O35263), Rattus norvegicus
Manually annotated by BRENDA team
MacRitchie, A.N.; Gardner, A.A.; Prescott, S.M.; Stafforini, D.M.
Molecular basis for susceptibility of plasma platelet-activating factor acetylhydrolase to oxidative inactivation
FASEB J.
21
1164-1176
2007
Homo sapiens, Mus musculus (A0JNU3 and Q61206 and Q61205)
Manually annotated by BRENDA team
Zhu, J.; Massey, J.B.; Mitchell-Leef, D.; Elsner, C.W.; Kort, H.I.; Roudebush, W.E.
Platelet-activating factor acetylhydrolase activity affects sperm motility and serves as a decapacitation factor
Fertil. Steril.
85
391-394
2006
Homo sapiens
Manually annotated by BRENDA team
Yamaguchi, N.; Koizumi, H.; Aoki, J.; Natori, Y.; Nishikawa, K.; Natori, Y.; Takanezawa, Y.; Arai, H.
Type I platelet-activating factor acetylhydrolase catalytic subunits over-expression induces pleiomorphic nuclei and centrosome amplification
Genes Cells
12
1153-1161
2007
Mus musculus
Manually annotated by BRENDA team
Kono, N.; Inoue, T.; Yoshida, Y.; Sato, H.; Matsusue, T.; Itabe, H.; Niki, E.; Aoki, J.; Arai, H.
Protection against oxidative stress-induced hepatic injury by intracellular type II platelet-activating factor acetylhydrolase by metabolism of oxidized phospholipids in vivo
J. Biol. Chem.
283
1628-1636
2008
Mus musculus (Q8VDG7), Mus musculus
Manually annotated by BRENDA team
Davis, B.; Koster, G.; Douet, L.J.; Scigelova, M.; Woffendin, G.; Ward, J.M.; Smith, A.; Humphres, J.; Burnand, K.G.; Macphee, C.H.; Postle, A.D.
Electrospray ionization mass spectrometry identifies substrates and products of lipoprotein-associated phospholipase A2 in oxidized human low density lipoprotein
J. Biol. Chem.
283
6428-6437
2007
Homo sapiens
Manually annotated by BRENDA team
Chen, J.; Yang, L.; Foulks, J.M.; Weyrich, A.S.; Marathe, G.K.; McIntyre, T.M.
Intracellular PAF catabolism by PAF acetylhydrolase counteracts continual PAF synthesis
J. Lipid Res.
48
2365-2376
2007
Homo sapiens
Manually annotated by BRENDA team
Caini, P.; Guerra, C.T.; Giannini, C.; Giannelli, F.; Gragnani, L.; Petrarca, A.; Solazzo, V.; Monti, M.; Laffi, G.; Zignego, A.L.
Modifications of plasma platelet-activating factor (PAF)-acetylhydrolase/PAF system activity in patients with chronic hepatitis C virus infection
J. Viral Hepat.
14
22-28
2007
Homo sapiens
Manually annotated by BRENDA team
Scott, B.T.; Olson, N.; Long, G.L.; Bovill, E.G.
Novel isoforms of intracellular platelet activating factor acetylhydrolase (PAFAH1b2) in human testis; encoded by alternatively spliced mRNAs
Prostaglandins Other Lipid Mediat.
85
69-80
2007
Homo sapiens, Homo sapiens (P68402)
Manually annotated by BRENDA team
Umemura, K.; Kato, I.; Hirashima, Y.; Ishii, Y.; Inoue, T.; Aoki, J.; Kono, N.; Oya, T.; Hayashi, N.; Hamada, H.; Endo, S.; Oda, M.; Arai, H.; Kinouchi, H.; Hiraga, K.
Neuroprotective role of transgenic PAF-acetylhydrolase II in mouse models of focal cerebral ischemia
Stroke
38
1063-1068
2007
Homo sapiens (Q99487), Homo sapiens
Manually annotated by BRENDA team
Lerman, A.; McConnell, J.P.
Lipoprotein-associated phospholipase A2: a risk marker or a risk factor?
Am. J. Cardiol.
101
11F-22F
2008
Homo sapiens
Manually annotated by BRENDA team
Anderson, J.L.
Lipoprotein-associated phospholipase A2: an independent predictor of coronary artery disease events in primary and secondary prevention
Am. J. Cardiol.
101
23F-33F
2008
Homo sapiens
Manually annotated by BRENDA team
Turk, R.; Juretic, D.; Geres, D.; Bacic, G.; Milesevic, M.; Flegar-Mestric, Z.; Turk, N.; Svetina, A.
Bovine platelet-activating factor acetylhydrolase (PAF-AH) activity related to fertility
Anim. Reprod. Sci.
105
344-353
2008
Bos taurus
Manually annotated by BRENDA team
Schmidt, E.B.; Koenig, W.; Khuseyinova, N.; Christensen, J.H.
Lipoprotein-associated phospholipase A2 concentrations in plasma are associated with the extent of coronary artery disease and correlate to adipose tissue levels of marine n-3 fatty acids
Atherosclerosis
196
420-424
2008
Homo sapiens
Manually annotated by BRENDA team
Rosenson, R.S.; Vracar-Grabar, M.; Helenowski, I.
Lipoprotein associated phospholipase A2 inhibition reduces generation of oxidized fatty acids: Lp-LPA2 reduces oxidized fatty acids
Cardiovasc. Drugs Ther.
22
55-58
2008
Homo sapiens
Manually annotated by BRENDA team
Stafforini, D.M.
Biology of platelet-activating factor acetylhydrolase (PAF-AH, lipoprotein associated phospholipase A2)
Cardiovasc. Drugs Ther.
23
73-83
2009
Homo sapiens
Manually annotated by BRENDA team
Brilakis, E.S.; Khera, A.; Saeed, B.; Banerjee, S.; McGuire, D.K.; Murphy, S.A.; de Lemos, J.A.
Association of lipoprotein-associated phospholipase A2 mass and activity with coronary and aortic atherosclerosis: findings from the Dallas Heart Study
Clin. Chem.
54
1975-1981
2008
Homo sapiens
Manually annotated by BRENDA team
Lavi, S.; Herrmann, J.; Lavi, R.; McConnell, J.P.; Lerman, L.O.; Lerman, A.
Role of lipoprotein-associated phospholipase A2 in atherosclerosis
Curr. Atheroscler. Rep.
10
230-235
2008
Homo sapiens
Manually annotated by BRENDA team
Foulks, J.M.; Weyrich, A.S.; Zimmerman, G.A.; McIntyre, T.M.
A yeast PAF acetylhydrolase ortholog suppresses oxidative death
Free Radic. Biol. Med.
45
434-442
2008
Schizosaccharomyces pombe
Manually annotated by BRENDA team
Gardner, A.A.; Reichert, E.C.; Topham, M.K.; Stafforini, D.M.
Identification of a domain that mediates association of platelet-activating factor acetylhydrolase with high density lipoprotein
J. Biol. Chem.
283
17099-17106
2008
Homo sapiens, Mus musculus
Manually annotated by BRENDA team
Samanta, U.; Bahnson, B.J.
Crystal structure of human plasma platelet-activating factor acetylhydrolase: structural implication to lipoprotein binding and catalysis
J. Biol. Chem.
283
31617-31624
2008
Homo sapiens (Q13093), Homo sapiens
Manually annotated by BRENDA team
Figueiredo, M.B.; Genta, F.A.; Garcia, E.S.; Azambuja, P.
Lipid mediators and vector infection: Trypanosoma rangeli inhibits Rhodnius prolixus hemocyte phagocytosis by modulation of phospholipase A2 and PAF-acetylhydrolase activities
J. Insect Physiol.
54
1528-1537
2008
Rhodnius prolixus
Manually annotated by BRENDA team
Tsoukatos, D.C.; Brocheriou, I.; Moussis, V.; Panopoulou, C.P.; Christofidou, E.D.; Koussissis, S.; Sismanidis, S.; Ninio, E.; Siminelakis, S.
Platelet-activating factor acetylhydrolase and transacetylase activities in human aorta and mammary artery
J. Lipid Res.
49
2240-2249
2008
Homo sapiens
Manually annotated by BRENDA team
McIntyre, T.M.; Prescott, S.M.; Stafforini, D.M.
The emerging roles of PAF acetylhydrolase
J. Lipid Res.
50
S255-S259
2009
Mammalia
Manually annotated by BRENDA team
Gomes, M.d.e..B.; Cobas, R.A.; Nunes, E.; Nery, M.; Castro-Faria-Neto, H.C.; Tibirica, E.
Serum platelet-activating factor acetylhydrolase activity: a novel potential inflammatory marker in type 1 diabetes
Prostaglandins Other Lipid Mediat.
87
42-46
2008
Homo sapiens
Manually annotated by BRENDA team
Samanta, U.; Wilder, C.; Bahnson, B.J.
Crystallization and preliminary X-ray crystallographic analysis of human plasma platelet activating factor acetylhydrolase
Protein Pept. Lett.
16
97-100
2009
Homo sapiens
Manually annotated by BRENDA team
Turk, R.; Habus, J.; Flegar-Mestric, Z.; Svetina, A.; Mojcec, V.; Perkov, S.; Belis, M.; Staresina, V.; Turk, N.
Serum platelet-activating factor acetylhydrolase and paraoxonase-1 activity in horses infected with Leptospira spp
Acta Trop.
118
97-100
2011
Equus caballus
Manually annotated by BRENDA team
Gardner, A.A.; Reichert, E.C.; Alexander, T.S.; Topham, M.K.; Stafforini, D.M.
Novel mechanism for regulation of plasma platelet-activating factor acetylhydrolase expression in mammalian cells
Biochem. J.
428
269-279
2010
Homo sapiens, Mus musculus
Manually annotated by BRENDA team
Pande, A.H.; Tillu, V.A.
Membrane lipid composition differentially modulates the function of human plasma platelet activating factor-acetylhydrolase
Biochim. Biophys. Acta
1811
46-56
2011
Homo sapiens
Manually annotated by BRENDA team
Liu, J.; Chen, R.; Marathe, G.K.; Febbraio, M.; Zou, W.; McIntyre, T.M.
Circulating platelet-activating factor is primarily cleared by transport, not intravascular hydrolysis by lipoprotein-associated phospholipase A2/PAF acetylhydrolase
Circ. Res.
108
469-477
2011
Mus musculus, Mus musculus BL6
Manually annotated by BRENDA team
Howard, K.M.; Abdel-Al, M.; Ditmyer, M.; Patel, N.
Lipopolysaccharide and platelet-activating factor stimulate expression of platelet-activating factor acetylhydrolase via distinct signaling pathways
Inflamm. Res.
60
735-744
2011
Homo sapiens
Manually annotated by BRENDA team
Zhou, G.; Marathe, G.K.; Willard, B.; McIntyre, T.M.
Intracellular erythrocyte PAF acetylhydrolase 1 inactivates aspirin in blood
J. Biol. Chem.
286
34820-34829
2011
Homo sapiens
Manually annotated by BRENDA team
Corte-Real, R.; Gomes, R.N.; Castro-Faria-Neto, H.C.; Azambuja, P.; Garcia, E.S.
The activity of platelet activating factor-acetyl hydrolase (PAF-AH) in the salivary glands of Rhodnius prolixus
J. Insect Physiol.
57
825-829
2011
Rhodnius prolixus
Manually annotated by BRENDA team
Wojcicka, G.; Jamroz-Wisniewska, A.; Marciniak, A.; Lowicka, E.; Beltowski, J.
The differentiating effect of glimepiride and glibenclamide on paraoxonase 1 and platelet-activating factor acetylohydrolase activity
Life Sci.
87
126-132
2010
Rattus norvegicus
Manually annotated by BRENDA team
Lu, J.; Pierce, M.; Franklin, A.; Jilling, T.; Stafforini, D.M.; Caplan, M.
Dual roles of endogenous platelet-activating factor acetylhydrolase in a murine model of necrotizing enterocolitis
Pediatr. Res.
68
225-230
2010
Mus musculus, Mus musculus C57/BL6J
Manually annotated by BRENDA team