Information on EC 3.1.1.25 - 1,4-lactonase

for references in articles please use BRENDA:EC3.1.1.25
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EC Tree
     3 Hydrolases
         3.1 Acting on ester bonds
             3.1.1 Carboxylic-ester hydrolases
                3.1.1.25 1,4-lactonase
IUBMB Comments
The enzyme is specific for 1,4-lactones with 4-8 carbon atoms. It does not hydrolyse simple aliphatic esters, acetylcholine, sugar lactones or substituted aliphatic lactones, e.g. 3-hydroxy-4-butyrolactone; requires Ca2+.
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Word Map
The enzyme appears in viruses and cellular organisms
Synonyms
ahl lactonase, ssopox, vmolac, levo-lactonase, vmut_2255, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
a 1,4-lactone + H2O = a 4-hydroxyacid
show the reaction diagram