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Disease on EC 3.1.1.2 - arylesterase

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DISEASE
TITLE OF PUBLICATION
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Abortion, Habitual
Paraoxonase-1 Polymorphisms (L55M/Q192R) and Activities (PONase/AREase) in Patients with Idiopathic Recurrent Early Pregnancy Loss: A Preliminary Study.
Abortion, Spontaneous
Paraoxonase-1 Polymorphisms (L55M/Q192R) and Activities (PONase/AREase) in Patients with Idiopathic Recurrent Early Pregnancy Loss: A Preliminary Study.
Acne Vulgaris
Oral isotretinoin therapy of acne patients decreases serum paraoxonase-1 activity through increasing oxidative stress.
Acromegaly
Serum paraoxonase level and paraoxonase polymorphism in patients with acromegaly.
Acute Coronary Syndrome
Association between HDL particles size and myeloperoxidase/ paraoxonase-1 (MPO/PON1) ratio in patients with acute coronary syndrome.
Association between Paraoxonase 1 (PON1) Polymorphisms and the Risk of Acute Coronary Syndrome in a North African Population.
Association between paraoxonase 1 activity and severity of coronary artery disease in patients with acute coronary syndromes.
Clinical and Genetic Association of Serum Paraoxonase and Arylesterase Activities With Cardiovascular Risk.
Effects of Cardiac Rehabilitation on High-Density Lipoprotein-mediated Cholesterol Efflux Capacity and Paraoxonase-1 Activity in Patients with Acute Coronary Syndrome.
Influence of high-density lipoprotein and paraoxonase-1 on platelet reactivity in patients with acute coronary syndromes receiving clopidogrel therapy.
Lack of association between serum paraoxonase-1 activity and residual platelet aggregation during dual anti-platelet therapy.
Oxidation and endothelial dysfunction biomarkers of atherosclerotic plaque instability. Studies of the vascular wall and blood.
Serum arylesterase activity is negatively correlated with inflammatory markers in patients with acute coronary syndromes.
[Association between paraoxonase concentration and risk of acute coronary syndrome].
Acute Kidney Injury
Association of paraoxonase 1 and oxidative stress with acute kidney injury in premature asphyxiated neonates.
Effect of continuous renal-replacement therapy on paraoxonase-1-related variables in patients with acute renal failure caused by septic shock.
Adenocarcinoma
Adenocarcinoma of the colon with choriocarcinoma in its metastases.
Adrenocortical Hyperfunction
Serum paraoxonase 1 and butyrylcholinesterase in dogs with hyperadrenocorticism.
alcohol dehydrogenase deficiency
Ecogenetic and pharmacogenetic studies in Hungary.
Ecogenetic studies in Atacameño Indians.
Alopecia Areata
Evaluation of Serum Paraoxonase, Arylesterase, Prolidase Activities and Oxidative Stress in Patients with Alopecia Areata.
Alzheimer Disease
A Meta-Analysis on the Relationship of the PON Genes and Alzheimer Disease.
Alzheimer's Disease and Paraoxonase 1 (PON1) Gene Polymorphisms.
Arylesterase Activity of Paraoxonase-1 in Serum and Cerebrospinal Fluid of Patients with Alzheimer's Disease and Vascular Dementia.
Assessment of Paraoxonase 1 Activity in Patients With Alzheimer's Disease and Vascular Dementia.
Association analysis of the paraoxonase-1 gene with Alzheimer's disease.
Association of adiponectin, leptin and resistin with inflammatory markers and obesity in dementia.
Association study of the paraoxonase 1 gene with the risk of developing Alzheimer's disease.
Codon 311 (Cys --> Ser) polymorphism of paraoxonase-2 gene is associated with apolipoprotein E4 allele in both Alzheimer's and vascular dementias.
Decreased arylesterase activity of paraoxonase-1 (PON-1) might be a common denominator of neuroinflammatory and neurodegenerative diseases.
Different pattern of association of paraoxonase Gln192-->Arg polymorphism with sporadic late-onset Alzheimer's disease and coronary artery disease.
Evaluating the link between Paraoxonase-1 levels and Alzheimer's disease development.
Genetic polymorphisms in older subjects with vascular or Alzheimer's dementia.
Gln192Arg polymorphism in paraoxonase 1 gene is associated with Alzheimer disease in a Chinese Han ethnic population.
Higher Levels of Oxidized Low Density Lipoproteins in Alzheimer's Disease Patients: Roles for Platelet Activating Factor Acetyl Hydrolase and Paraoxonase-1.
Involvement of paraoxonase 1 genetic variants in Alzheimer's disease neuropathology.
Lack of an association between Paraoxonase 1 gene polymorphisms (Q192R, L55M) and Alzheimer's disease: A meta-analysis.
No association of paraoxonase gene polymorphism with atherosclerosis or Alzheimer's disease.
Normalization of gene expression using SYBR green qPCR: A case for paraoxonase 1 and 2 in Alzheimer's disease brains.
Paraoxonase 1 (PON1) gene -108C>T and p.Q192R polymorphisms and arylesterase activity of the enzyme in patients with dementia.
Paraoxonase 1 192/55 gene polymorphisms in Alzheimer's disease.
Paraoxonase 1 decline and lipid peroxidation rise reflect a degree of brain atrophy and vascular impairment in dementia.
Paraoxonase 1 Gene Polymorphisms Do Not Influence the Response to Treatment in Alzheimer's Disease.
Paraoxonase 1, B Vitamins Supplementation, and Mild Cognitive Impairment.
Paraoxonase activity and dementia.
Paraoxonase gene polymorphism and the risk for Alzheimer's disease in the polish population.
Paraoxonase-1 and -3 Protein Expression in the Brain of the Tg2576 Mouse Model of Alzheimer's Disease.
Paraoxonase-1 polymorphisms in Alzheimer's disease, Parkinson's disease, and AD-PD spectrum diseases.
Polymorphisms at the paraoxonase 1 L55M and Q192R loci affect the pathophysiology of Alzheimer's disease: emphasis on the cholinergic system and beta-amyloid levels.
Polymorphisms in the PON gene cluster are associated with Alzheimer disease.
Possible association between Cys311Ser polymorphism of paraoxonase 2 gene and late-onset Alzheimer's disease in Chinese.
Profile of the Paraoxonase 1 (PON1) Gene 192Q/R Polymorphism and Clinical Associations among Older Singaporean Chinese with Alzheimer's and Mixed Dementia.
Serum HDL Associated Antioxidant Activity in Alzheimer's Disease: Paraoxonase1 and Dysfunctional HDL.
Serum paraoxonase activity changes in patients with Alzheimer's disease and vascular dementia.
Serum paraoxonase activity is associated with variants in the PON gene cluster and risk of Alzheimer disease.
Serum paraoxonase and arylesterase activities of paraoxonase-1 (PON-1), mild cognitive impairment, and 2-year conversion to dementia: A pilot study.
Synergistic Epistasis of Paraoxonase 1 (rs662 and rs85460) and Apolipoprotein E4 Genes in Pathogenesis of Alzheimer's Disease and Vascular Dementia.
Urinary 8-hydroxy-2'-deoxyguanosine level and plasma paraoxonase 1 activity with Alzheimer's disease.
[Gln192Arg polymorphism of the paraoxonase-1 gene is not associated with Alzheimer's disease in Chinese]
[Paraoxonase 1 gene Gln192Arg polymorphism in and Alzheimer disease]
Amyloidosis
Serum esterase activity in reactive systemic amyloidosis and its relation to amyloid A degrading activity.
Amyotrophic Lateral Sclerosis
A gene-environment study of the paraoxonase 1 gene and pesticides in amyotrophic lateral sclerosis.
A large-scale international meta-analysis of paraoxonase gene polymorphisms in sporadic ALS.
Association analysis of PON polymorphisms in sporadic ALS in a Chinese population.
Association of paraoxonase gene cluster polymorphisms with ALS in France, Quebec, and Sweden.
Interaction between PON1 and population density in amyotrophic lateral sclerosis.
Lack of association of PON polymorphisms with sporadic ALS in an Italian population.
Motor neuron diseases and neurotoxic substances: a possible link?
Neuropathy target esterase gene mutations cause motor neuron disease.
Paraoxonase 1 (PON1) organophosphate hydrolysis is not reduced in ALS.
Paraoxonase 1 Q192R and L55M polymorphisms and susceptibility to amyotrophic lateral sclerosis: a meta-analysis.
Paraoxonase gene mutations in amyotrophic lateral sclerosis.
Paraoxonase promoter and intronic variants modify risk of sporadic amyotrophic lateral sclerosis.
Paraoxonase-1 Q192R polymorphism and risk of sporadic amyotrophic lateral sclerosis.
Rare and common paraoxonase gene variants in amyotrophic lateral sclerosis patients.
Anemia
Administration of exogenous erythropoietin beta affects lipid peroxidation and serum paraoxonase-1 activity and concentration in predialysis patients with chronic renal disease and anaemia.
Assessment of paraoxonase and arylesterase activities in patients with iron deficiency anemia.
Comparison of serum paraoxonase and arylesterase activities between iron deficiency anemia patients and chronic kidney disease patients with anemia.
Effects of Iron Supplementation With and Without Docosahexaenoic Acid on the Cardiovascular Disease Risk Based on Paraoxonase-1, hs-CRP, and ApoB/ApoA-I Ratio in Women with Iron Deficiency Anemia.
Paraoxonase 1 (PON1) status in gastroesophageal malignancies and associated paraneoplastic syndromes - connection with inflammation.
Paraoxonase and arylesterase activities in children with iron deficiency anemia and vitamin B12 deficiency anemia.
Paraoxonase and arylesterase activity with oxidative status in children with thalassemia major.
Reduced antioxidant capacity in children with iron deficiency and iron-deficiency anemia.
Serum paraoxonase 1 activity in patients with iron deficiency anemia.
Anemia, Iron-Deficiency
Assessment of paraoxonase and arylesterase activities in patients with iron deficiency anemia.
Comparison of serum paraoxonase and arylesterase activities between iron deficiency anemia patients and chronic kidney disease patients with anemia.
Effects of Iron Supplementation With and Without Docosahexaenoic Acid on the Cardiovascular Disease Risk Based on Paraoxonase-1, hs-CRP, and ApoB/ApoA-I Ratio in Women with Iron Deficiency Anemia.
Paraoxonase and arylesterase activities in children with iron deficiency anemia and vitamin B12 deficiency anemia.
Serum paraoxonase 1 activity in patients with iron deficiency anemia.
Anemia, Sickle Cell
Paraoxonases (PON) 1, 2, and 3 Polymorphisms and PON-1 Activities in Patients with Sickle Cell Disease.
Angina Pectoris
Pro-inflammatory Mediators and Oxidative Stress: Therapeutic Markers for Recurrent Angina Pectoris after Coronary Artery Stenting in Elderly Patients.
Anovulation
Estimation of gene-environment interaction by pooling biospecimens.
Anthrax
Serum paraoxonase activity and oxidative stress levels in patients with cutaneous anthrax.
Antiphospholipid Syndrome
Antibodies against beta(2)-glycoprotein I complexed with an oxidised lipoprotein relate to intima thickening of carotid arteries in primary antiphospholipid syndrome.
Antibodies to high-density lipoprotein and beta2-glycoprotein I are inversely correlated with paraoxonase activity in systemic lupus erythematosus and primary antiphospholipid syndrome.
Association between paraoxonase-1 gene Q192R and L55M polymorphisms in systemic lupus erythematosus (SLE) and anti-phospholipid syndrome (APS) in a population from Cairo of Egypt.
Vascular abnormalities, paraoxonase activity, and dysfunctional HDL in primary antiphospholipid syndrome.
Aortic Aneurysm, Abdominal
Paraoxonase-1 overexpression prevents experimental abdominal aortic aneurysm progression.
The Paraoxonase Gene Cluster Protects Against Abdominal Aortic Aneurysm Formation.
Aortic Valve Insufficiency
Decreased paraoxonase 1, arylesterase enzyme activity, and enhanced oxidative stress in patients with mitral and aortic valve insufficiency.
Aortic Valve Stenosis
Expression levels of paraoxonase-1 in aortic valve tissue are associated with the progression of calcific aortic valve stenosis.
Functional SNP in the 3'UTR of PON1 is Associated with the Risk of Calcific Aortic Valve Stenosis via MiR-616.
Paraoxonase activity might be predictive of the severity of aortic valve stenosis.
Appendicitis
Total oxidant status, total antioxidant status, and paraoxonase activity in acute appendicitis.
Arteriosclerosis
Antioxidant and anti-inflammatory role of paraoxonase 1: implication in arteriosclerosis diseases.
Atherosclerosis and arteriosclerosis parameters in stroke patients associate with paraoxonase polymorphism and esterase activities.
Arthritis
Evaluation of paraoxonase and arylesterase activities in Egyptian patients with ankylosing spondylitis.
Arthritis, Psoriatic
HDL associated paraoxonase-1 activity correlates with systemic inflammation, disease activity and cardiovascular risk factors in psoriatic disease.
Arthritis, Rheumatoid
Anti-cyclic citrullinated peptide antibodies and paraoxonase-1 polymorphism in rheumatoid arthritis.
Antibodies to paraoxonase 1 are associated with oxidant status and endothelial activation in rheumatoid arthritis.
Assessment of paraoxonase 1 activity and malondialdehyde levels in patients with rheumatoid arthritis.
Association between activity and genotypes of paraoxonase1 L55M (rs854560) increases the disease activity of rheumatoid arthritis through oxidative stress.
Association of Paraoxonase 1 gene polymorphisms and enzyme activity with carotid plaque in rheumatoid arthritis.
Association of Paraoxonase 1 Polymorphism and Serum 25-Hydroxyvitamin D with the Risk of Cardiovascular Disease in Patients with Rheumatoid Arthritis.
Associations between paraoxonase 1 (PON1) polymorphisms and susceptibility and PON1 activity in rheumatoid arthritis patients, and comparison of PON1 activity in patients and controls: a meta-analysis.
Beta-Carotene, Vitamin E, MDA, Glutathione Reductase and Arylesterase Activity Levels in Patients with Active Rheumatoid Arthritis.
Effect of Fish Oil Supplements on Serum Paraoxonase Activity in Female Patients with Rheumatoid Arthritis: A Double-blind Randomized Controlled Trial.
Functional implications of single nucleotide polymorphisms rs662 and rs854860 on the antioxidative activity of paraoxonase1 (PON1) in patients with rheumatoid arthritis.
Lack of association between paraoxonase-1 Q192R polymorphism and rheumatoid arthritis in southeast Iran.
Paraoxonase 1 Phenotype and Protein N-Homocysteinylation in Patients with Rheumatoid Arthritis: Implications for Cardiovascular Disease.
Paraoxonase and arylesterase levels in rheumatoid arthritis.
Serum esterase activity in reactive systemic amyloidosis and its relation to amyloid A degrading activity.
Serum paraoxonase activity decreases in rheumatoid arthritis.
The L55M polymorphism of paraoxonase-1 is a risk factor for rheumatoid arthritis.
arylesterase deficiency
Paraoxonase 1 deficiency and hyperhomocysteinemia alter the expression of mouse kidney proteins involved in renal disease.
Paraoxonase 1 deficiency in mice is associated with reduced steroid biosynthesis: Effects on HDL binding, cholesteryl ester accumulation and scavenger receptor type BI expression.
Paraoxonase and arylesterase activities in children with iron deficiency anemia and vitamin B12 deficiency anemia.
Paraoxonase promoter polymorphism T(-107)C and relative paraoxonase deficiency as determinants of risk of coronary artery disease.
Paraoxonase-1 deficiency in mice predisposes to vascular inflammation, oxidative stress, and thrombogenicity in the absence of hyperlipidemia.
Paraoxonase-1 Deficiency Is Associated with Severe Liver Steatosis in Mice Fed a High-fat High-cholesterol Diet: A Metabolomic Approach.
Paraoxonase1 deficiency in mice is associated with hypotension and increased levels of 5,6-epoxyeicosatrienoic acid.
Asthma
Association between the oxidative status, Vitamin D levels and respiratory function in asthmatic children.
Evaluation of serum paraoxonase and arylesterase activities in subjects with asthma and chronic obstructive lung disease.
Gene expression profiling of experimental asthma reveals a possible role of paraoxonase-1 in the disease.
Influences of PON1 on airway inflammation and remodeling in bronchial asthma.
Oxidative status and paraoxonase activity in children with asthma.
Plasma paraoxonase activities, lipoprotein oxidation, and trace element interaction in asthmatic patients.
Plasma paraoxonase, oxidative status level, and their relationship with asthma control test in children with asthma.
Plasma protein thiols: an early marker of oxidative stress in asthma and chronic obstructive pulmonary disease.
Astrocytoma
Two common nonsynonymous paraoxonase 1 (PON1) gene polymorphisms and brain astrocytoma and meningioma.
Atherosclerosis
A homogeneous cell-based assay for measurement of endogenous paraoxonase 1 activity.
A multiplex PCR-based DNA assay for the detection of paraoxonase gene cluster polymorphisms.
A variant of human paraoxonase/arylesterase (HUMPONA) gene is a risk factor for coronary artery disease.
Accuracy and biological variation of human serum paraoxonase 1 activity and polymorphism (Q192R) by kinetic enzyme assay.
Activity of paraoxonase 1 (PON1) and its relationship to markers of lipoprotein oxidation in healthy Slovaks.
Activity of paraoxonase 1 and lipid profile in healthy children.
Addressing the link between paraoxonase-1 gene variants and the incidence of early onset myocardial infarction.
Adenovirus mediated expression of human paraoxonase 2 protects against the development of atherosclerosis in apolipoprotein E-deficient mice.
Alpha-tocopherol supplementation prevents the exercise-induced reduction of serum paraoxonase 1/arylesterase activities in healthy individuals.
Alteration of PON1 Activity in Adult and Childhood Obesity and Its Relation to Adipokine Levels.
Altered activities of anti-atherogenic enzymes LCAT, paraoxonase, and platelet-activating factor acetylhydrolase in atherosclerosis-susceptible mice.
Analysis of paraoxonase (PON1) L55M status requires both genotype and phenotype.
Analysis of paraoxonase 1 (PON1) genetic polymorphisms and activities as risk factors for ischemic stroke in Turkish population.
Anti-apolipoprotein A-I antibodies and paraoxonase 1 activity in Systemic Lupus Erythematosus.
Anti-inflammatory properties of paraoxonase-1 in atherosclerosis.
Apolipoprotein J: A New Predictor and Therapeutic Target in Cardiovascular Disease?
Assessment of early atherosclerotic findings in patients with nasal polyposis.
Assessment of paraoxonase activities in patients with knee osteoarthritis.
Assessment of paraoxonase and arylesterase activities in patients with iron deficiency anemia.
Assessment of Small C-Fiber Status for Screening of Oxidative Stress in Patients at Risk of Diabetes.
Assessment of the role of paraoxonase gene polymorphism (Q192R) and paraoxonase activity in the susceptibility to atherosclerosis among lead-exposed workers.
Association between PON1 rs662 polymorphism and coronary artery disease.
Association between the paraoxonase-1 192Q>R allelic variant and coronary endothelial dysfunction in patients with early coronary artery disease.
Association of carotid intima media thickness with atherogenic index of plasma, apo B/apo A-I ratio and paraoxonase activity in patients with non-alcoholic fatty liver disease.
Association of lead, cadmium and mercury with paraoxonase 1 activity and malondialdehyde in a general population in Southern Brazil.
Association of paraoxonase 55 and 192 gene polymorphisms on serum homocysteine concentrations in preeclampsia.
Association of paraoxonase activity and atherosclerosis in patients with chronic hepatitis B.
Association of paraoxonase activity and coronary blood flow.
Association of paraoxonase activity and coronary collateral flow.
Association of paraoxonase polymorphisms with carotid artery atherosclerosis in essential hypertension patients.
Association of paraoxonase-1 L55M and Q192R polymorphisms with PCOS risk and potential risk factors for atherosclerosis.
Atherogenesis: hyperhomocysteinemia interactions with LDL, macrophage function, paraoxonase 1, and exercise.
Atheroprotective mechanisms of HDL.
Atherosclerosis and arteriosclerosis parameters in stroke patients associate with paraoxonase polymorphism and esterase activities.
Atorvastatin effect on high-density lipoprotein-associated paraoxonase activity and oxidative DNA damage.
Atorvastatin effect on the distribution of high-density lipoprotein subfractions and human paraoxonase activity.
Betaine protects chronic alcohol and omega-3 PUFA-mediated down-regulations of PON1 gene, serum PON1 and homocysteine thiolactonase activities with restoration of liver GSH.
Carotid intima-media thickness and paraoxonase activity in patients with ankylosing spondylitis.
Clinical and Genetic Association of Serum Paraoxonase and Arylesterase Activities With Cardiovascular Risk.
Concerning the Significance of Paraoxonase-1 and SR-B1 Genes in Atherosclerosis.
Coronary artery disease risk factors in patients with schizophrenia: effects of short term antipsychotic treatment.
Coronary artery disease risk in Chinese type 2 diabetics: is there a role for paraxonase 1 gene (Q192R) polymorphism?
Decreased arylesterase activity of paraoxonase-1 (PON-1) might be a common denominator of neuroinflammatory and neurodegenerative diseases.
Determinants of homocysteine-thiolactonase activity of the paraoxonase-1 (PON1) protein in humans.
Dietary modifications and gene polymorphisms alter serum paraoxonase activity in healthy women.
Diminished antioxidant activity of high-density lipoprotein-associated proteins in chronic kidney disease.
Diminished antioxidant activity of high-density lipoprotein-associated proteins in systolic heart failure.
Effect of atorvastatin therapy on oxidant-antioxidant status and atherosclerotic plaque formation.
Effect of Eicosapentaenoic Acid Supplementation on Paraoxonase 2 Gene Expression in Patients with Type 2 Diabetes Mellitus: a Randomized Double-blind Clinical Trial.
Effect of glycation of high density lipoproteins on their physicochemical properties and on paraoxonase activity.
Effect of homocysteinylation on high density lipoprotein physico-chemical properties.
Effect of levothyroxine replacement therapy on paraoxonase-1 and carotid intima-media thickness in subclinical hypothyroidism.
Effect of Quercetin on Paraoxonase 2 Levels in RAW264.7 Macrophages and in Human Monocytes--Role of Quercetin Metabolism.
Effects of antiretroviral treatment on paraoxonase 1 (PON1) activity in rats.
Effects of cholesterol supplementation on antioxidant enzyme activities in rat hepatic tissues: possible implications of hepatic paraoxonase in atherogenesis.
Effects of intravenous apolipoprotein A-I/phosphatidylcholine discs on paraoxonase and platelet-activating factor acetylhydrolase in human plasma and tissue fluid.
Efficacy of nobiletin in improving hypercholesterolemia and nonalcoholic fatty liver disease in high-cholesterol diet-fed mice.
Endurance training reduces circulating asymmetric dimethylarginine and myeloperoxidase levels in persons at risk of coronary events.
Evaluation of oxidative stress, the activities of paraoxonase and arylesterase in patients with subclinic hypothyroidism.
Evaluation of the future atherosclerotic heart disease with oxidative stress and carotid artery intima media thickness in gestational diabetes mellitus.
Evidence for a paraoxonase-independent inhibition of low-density lipoprotein oxidation by high-density lipoprotein.
Expression of major HDL-associated antioxidant PON-1 is gender dependent and regulated during inflammation.
Facilitated replacement of Kupffer cells expressing a paraoxonase-1 transgene is essential for ameliorating atherosclerosis in mice.
Frequency of paraoxonase 192/55 polymorphism in an Iranian population.
Functionalized imidazolium and benzimidazolium salts as paraoxonase 1 inhibitors: Synthesis, characterization and molecular docking studies.
Functionally Defective High-Density Lipoprotein and Paraoxonase: A Couple for Endothelial Dysfunction in Atherosclerosis.
Gene activation, apolipoprotein A-I/high density lipoprotein, atherosclerosis prevention and longevity.
Genetic polymorphisms and activity of PON1 in a Mexican population.
Genetic polymorphisms of paraoxonase 1 and susceptibility to atherogenesis.
Genetic variations of the paraoxonase gene in patients with coronary artery disease.
Genetic-dietary regulation of serum paraoxonase expression and its role in atherogenesis in a mouse model.
HDL capacity to inhibit LDL oxidation in well-trained triathletes.
HDL--associated paraoxonase 1 (PON1) and dietary antioxidants attenuate lipoprotein oxidation, macrophage foam cells formation and atherosclerosis development.
Hepatic paraoxonase 1 ameliorates dysfunctional high-density lipoprotein and atherosclerosis in scavenger receptor class B type I deficient mice.
High C-reactive protein and low paraoxonase1 in diabetes as risk factors for coronary heart disease.
High Concentration of Medium-Sized HDL Particles and Enrichment in HDL Paraoxonase 1 Associate With Protection From Vascular Complications in People With Long-standing Type 1 Diabetes.
High prevalence of low serum paraoxonase-1 in subjects with coronary artery disease.
High-dose taurine supplementation increases serum paraoxonase and arylesterase activities in experimental hypothyroidism.
Higher frequency of paraoxonase gene polymorphism and cardiovascular impairment among Brazilian Fabry Disease patients.
Human paraoxonase gene cluster overexpression alleviates angiotensin II-induced cardiac hypertrophy in mice.
Human Paraoxonase Gene Cluster Transgenic Overexpression Represses Atherogenesis and Promotes Atherosclerotic Plaque Stability in ApoE-Null Mice.
Human paraoxonase gene polymorphisms and coronary artery disease risk.
Human paraoxonase-1 (PON1): Gene structure and expression, promiscuous activities and multiple physiological roles.
Human paraoxonase-1 overexpression inhibits atherosclerosis in a mouse model of metabolic syndrome.
Hyperhomocysteinemia, paraoxonase activity and risk of coronary artery disease.
Impact of paraoxonase polymorphism (Q192R) on endothelial function in intact coronary circulation.
Impaired hepatic insulin signaling in PON2 deficient mice - a novel role for the PON2/ApoE axis on macrophage inflammatory response.
Increased immunolocalization of paraoxonase, clusterin, and apolipoprotein A-I in the human artery wall with the progression of atherosclerosis.
Increased levels of anti-heat-shock protein 60 (anti-Hsp60) indicate endothelial dysfunction, atherosclerosis and cardiovascular diseases in patients with mixed connective tissue disease.
Increased levels of high-density lipoprotein cholesterol are ineffective in inhibiting the development of immune responses to oxidized low-density lipoprotein and atherosclerosis in transgenic rabbits expressing human apolipoprotein (apo) A-I with severe hypercholesterolaemia.
Induction of paraoxonase 1 and apolipoprotein A-I gene expression by aspirin.
Infection and inflammation-induced proatherogenic changes of lipoproteins.
Interaction between polyphenols intake and PON1 gene variants on markers of cardiovascular disease: a nutrigenetic observational study.
Interaction of folate intake and the paraoxonase Q192R polymorphism with risk of incident coronary heart disease and ischemic stroke: the atherosclerosis risk in communities study.
Investigation of the relationship between atherosclerosis and paraoxonase or homocysteine thiolactonase activity in patients with type 2 diabetes mellitus using a commercially available assay.
Iron-ascorbic acid-induced oxidant stress and its quenching by paraoxonase 1 in HDL and the liver: comparison between humans and rats.
Is elevated high-density lipoprotein cholesterol always good for coronary heart disease?
Is it just paraoxonase 1 or are other members of the paraoxonase gene family implicated in atherosclerosis?
Is paraoxonase related to atherosclerosis.
Lead exposure is associated with decreased serum paraoxonase 1 (PON1) activity and genotypes.
Light, but not heavy alcohol drinking, stimulates paraoxonase by upregulating liver mRNA in rats and humans.
Low paraoxonase 1 arylesterase activity and high von Willebrand factor levels are associated with severe coronary atherosclerosis in patients with non-diabetic stable coronary artery disease.
Low paraoxonase activity predicts coronary events in the Caerphilly Prospective Study.
Macrophage foam cell formation during early atherogenesis is determined by the balance between pro-oxidants and anti-oxidants in arterial cells and blood lipoproteins.
Macrophage paraoxonase 2 regulates calcium homeostasis and cell survival under endoplasmic reticulum stress conditions and is sufficient to prevent the development of aggravated atherosclerosis in paraoxonase 2 deficiency/apoE(-/-) mice on a Western diet.
Macrophages from alpha 7 nicotinic acetylcholine receptor knockout mice demonstrate increased cholesterol accumulation and decreased cellular paraoxonase expression: A possible link between the nervous system and atherosclerosis development.
Mapping of microsatellite loci and association of aorta atherosclerosis with LG VI markers in the rabbit.
Methionine sulfoxide reductase A attenuates atherosclerosis via repairing dysfunctional HDL in scavenger receptor class B type I deficient mice.
Mildly oxidized LDL induces an increased apolipoprotein J/paraoxonase ratio.
Modulation of paraoxonase 1 (PON1) activity and protein N-homocysteinylation by bisphosphonates in rats.
Modulation of paraoxonase 1 and protein N-homocysteinylation by leptin and the synthetic liver X receptor agonist T0901317 in the rat.
Molecular variant of the human paraoxonase/arylesterase gene is associated with central retinal vein occlusion in the Japanese population.
Myeloperoxidase, paraoxonase-1, and HDL form a functional ternary complex.
Myeloperoxidase-induced modification of HDL by isolevuglandins inhibits paraoxonase-1 activity.
No association of paraoxonase gene polymorphism with atherosclerosis or Alzheimer's disease.
No association of paraoxonase genotype or atherosclerosis with cerebral amyloid angiopathy.
Non-diabetic metabolic syndrome and obesity do not affect serum paraoxonase and arylesterase activities but do affect oxidative stress and inflammation.
Normal lipid metabolism, familial hyperlipidaemia, lipid intervention and their benefits.
Oral small peptides render HDL antiinflammatory in mice and monkeys and reduce atherosclerosis in ApoE null mice.
Oxidation of apolipoprotein B-containing lipoproteins and serum paraoxonase/arylesterase activities in major depressive disorder.
Oxidative status and serum PON1 activity in beta-thalassemia minor.
Oxidative stress in vascular disease and its pharmacological prevention.
Oxidative stress in white coat hypertension; role of paraoxonase.
Oxidized low density lipoprotein: atherogenic and proinflammatory characteristics during macrophage foam cell formation. An inhibitory role for nutritional antioxidants and serum paraoxonase.
Paraoxonase (PON)-1: a brief overview on genetics, structure, polymorphisms and clinical relevance.
Paraoxonase (PON1) activity in patients with subclinical thoracic aortic atherosclerosis.
Paraoxonase (Pon1) Q192R polymorphism and serum Pon1 activity in diabetic patients on maintenance hemodialysis.
Paraoxonase 1 (PON1) and pomegranate influence circadian gene expression and period length.
Paraoxonase 1 (PON1) attenuates macrophage oxidative status: studies in PON1 transfected cells and in PON1 transgenic mice.
Paraoxonase 1 (PON1) polymorphisms, haplotypes and activity in predicting cad risk in North-West Indian Punjabis.
Paraoxonase 1 (Q192R) gene polymorphism, coronary heart disease and the risk of a new acute coronary event.
Paraoxonase 1 Activity, Polymorphism and Atherosclerosis Risk Factors in Patients Undergoing Coronary Artery Surgery.
Paraoxonase 1 and atherosclerosis-related diseases.
Paraoxonase 1 and atherosclerosis: is the gene or the protein more important?
Paraoxonase 1 and HDL maturation.
Paraoxonase 1 concerning dyslipidaemia, cardiovascular diseases, and mortality in haemodialysis patients.
Paraoxonase 1 gene promoter polymorphisms are associated with the extent of stenosis in coronary arteries.
Paraoxonase 1 gene Q192R polymorphism affects stroke and myocardial infarction risk.
Paraoxonase 1 gene transfer lowers vascular oxidative stress and improves vasomotor function in apolipoprotein E-deficient mice with pre-existing atherosclerosis.
Paraoxonase 1 Interactions with HDL, Antioxidants and Macrophages Regulate Atherogenesis - A Protective Role for HDL Phospholipids.
Paraoxonase 1 overexpression in mice and its effect on high-density lipoproteins.
Paraoxonase 1 Phenotype and Protein N-Homocysteinylation in Patients with Rheumatoid Arthritis: Implications for Cardiovascular Disease.
Paraoxonase 1 polymorphism and prenatal pesticide exposure associated with adverse cardiovascular risk profiles at school age.
Paraoxonase 1 polymorphisms as the risk factor of coronary heart disease in a Thai population.
Paraoxonase 1 Q192R (PON1-192) polymorphism is associated with reduced lipid peroxidation in healthy young men on a low-carotenoid diet supplemented with tomato juice.
Paraoxonase 1 Q192R (PON1-192) polymorphism is associated with reduced lipid peroxidation in R-allele-carrier but not in QQ homozygous elderly subjects on a tomato-rich diet.
Paraoxonase 1, atherosclerosis and arterial stiffness in renal patients.
Paraoxonase 192 Gln/Arg gene polymorphism, coronary artery disease, and myocardial infarction in type 2 diabetes.
Paraoxonase 2 Deficiency Alters Mitochondrial Function and Exacerbates the Development of Atherosclerosis.
Paraoxonase 2 Induces a Phenotypic Switch in Macrophage Polarization Favoring an M2 Anti-Inflammatory State.
Paraoxonase activity in glomerulonephritic patients.
Paraoxonase activity in human pericardial fluid: its relationship to coronary artery disease.
Paraoxonase and arylesterase activities in children with iron deficiency anemia and vitamin B12 deficiency anemia.
Paraoxonase and arylesterase activities in fibromyalgia.
Paraoxonase and arylesterase activity with oxidative status in children with thalassemia major.
Paraoxonase and atherosclerosis.
Paraoxonase and other coronary risk factors in a community-based cohort.
Paraoxonase gene polymorphism and serum activity in progressive IgA nephropathy.
Paraoxonase gene polymorphism, serum lipid, and oxidized low-density lipoprotein in preeclampsia.
Paraoxonase gene polymorphisms and stroke severity.
Paraoxonase genotype, LDL-oxidation and carotid atherosclerosis in male life-long smokers.
Paraoxonase is reduced in patients with growth hormone deficiency: A novel risk factor for atherosclerosis.
Paraoxonase producing PON1 gene M/L55 polymorphism is related to autopsy-verified artery-wall atherosclerosis.
Paraoxonase, oxidized low density lipoprotein, monocyte chemoattractant protein-1 and adhesion molecules are associated with macrovascular complications in patients with type 2 diabetes mellitus.
Paraoxonase-1 (PON1) activity as a risk factor for atherosclerosis in chronic renal failure patients.
Paraoxonase-1 activity as a marker of atherosclerosis is not associated with low bone mineral density in healthy postmenopausal women.
Paraoxonase-1 and adipokines: Potential links between obesity and atherosclerosis.
Paraoxonase-1 and oxidative status in common Mediterranean {beta}-thalassaemia mutations trait, and their relations to atherosclerosis.
Paraoxonase-1 and Symptomatic Status in Carotid Artery Disease.
Paraoxonase-1 arylesterase activity is an independent predictor of myeloperoxidase levels in overweight patients with or without cardiovascular complications.
Paraoxonase-1 deficiency in mice predisposes to vascular inflammation, oxidative stress, and thrombogenicity in the absence of hyperlipidemia.
Paraoxonase-1 gene haplotypes are associated with metabolic disturbances, atherosclerosis, and immunologic outcome in HIV-infected patients.
Paraoxonase-1 gene Leu-Met55 and Gln-Arg192 polymorphisms are not associated with carotid artery atherosclerosis in a population-based cohort.
Paraoxonase-1 gene Q192R and L55M polymorphisms and risk of cardiovascular disease in Egyptian patients with type 2 diabetes mellitus.
Paraoxonase-1 is a better indicator than HDL of Atherosclerosis - A pilot study in North Indian population.
Paraoxonase-1: Characteristics and role in atherosclerosis and carotid artery disease.
Paraoxonase-2 Modulates Stress Response of Endothelial Cells to Oxidized Phospholipids and a Bacterial Quorum-Sensing Molecule.
Paraoxonase: biochemistry, genetics and relationship to plasma lipoproteins.
Plasma Paraoxonase-1, Oxidized Low-Density Lipoprotein and Lipid Peroxidation Levels in Gout Patients.
Platelet-activating factor acetylhydrolase, and not paraoxonase-1, is the oxidized phospholipid hydrolase of high density lipoprotein particles.
Polymorphisms and the expression of genes encoding enzymes involved in cardiovascular diseases.
PON gene polymorphisms and ischaemic stroke: a systematic review and meta analysis.
PON1 and Mediterranean Diet.
PON1 lactonase activity and its association with cardiovascular disease.
PON1, a new biomarker of cardiovascular disease, is low in patients with systemic vasculitis.
PON2 gene variants are associated with clinical manifestations of cardiovascular disease in familial hypercholesterolemia patients.
Potential Association of Paraoxonase 1, Type 2 Diabetes Mellitus and Periodontitis.
Protective effects of Xiongshao Capsule () on anti-inflammatory function of high-density lipoprotein in atherosclerosis rabbit model.
Q192R polymorphism in the PON1 gene and familial hypercholesterolemia in a Saudi population.
R192Q paraoxonase gene variant is associated with a change in HDL-cholesterol level during dietary caloric restriction in nondiabetic healthy males.
Racial differences in paraoxonase-1 (PON1): a factor in the health of southerners?
Reduced antioxidant capacity in children with iron deficiency and iron-deficiency anemia.
Reduced paraoxonase 1 activity as a marker for severe coronary artery disease.
Reduced paraoxonase1 activity is a risk for atherosclerosis in patients with systemic lupus erythematosus.
Reduced postprandial serum paraoxonase activity after a meal rich in used cooking fat.
Relationship between rs854560
Relationship between selected oxidative stress markers and lipid risk factors for cardiovascular disease in middle-aged adults and its possible clinical relevance.
Relationship between serum paraoxonase and homocysteine thiolactonase activity, adipokines, and asymmetric dimethyl arginine concentrations in renal transplant patients.
Relationship between the esterase paraoxonase-1 (PON1) and metal concentrations in the whole blood of Inuit in Canada.
Relationship of endogenous hyperleptinemia to serum paraoxonase 1, cholesteryl ester transfer protein, and lecithin cholesterol acyltransferase in obese individuals.
Relationship of human paraoxonase-1 serum activity and genotype with atherosclerosis in individuals from the Deep South.
Relationship of paraoxonase-1, malondialdehyde and mean platelet volume with markers of atherosclerosis in familial Mediterranean fever: an observational study.
Relationship of serum resistin level to traits of metabolic syndrome and serum paraoxonase 1 activity in a population with a broad range of body mass index.
Renal cortical thickness and PON1 activity both decrease in chronic renal failure.
Role of JNK and c-Jun signaling pathway in regulation of human serum paraoxonase-1 gene transcription by berberine in human HepG2 cells.
Rosiglitazone modulates fasting and post-prandial paraoxonase 1 activity in type 2 diabetic patients.
Serum Amyloid A, Paraoxonase-1 Activity, and Apolipoprotein Concentrations as Biomarkers of Subclinical Atherosclerosis Risk in Adrenal Incidentaloma Patients.
Serum cystatin C is a determinant of paraoxonase activity in hemodialyzed and renal transplanted patients.
Serum Paraoxonase (PON1) Activity in North-West Indian Punjabi's with Acute Myocardial Infarction.
Serum paraoxonase 1 activity and oxidant/antioxidant status in Saudi women with polycystic ovary syndrome.
Serum paraoxonase 1 activity in women with metabolic syndrome.
Serum paraoxonase activities in hemodialyzed uremic patients: cohort study.
Serum paraoxonase activity and oxidative stress in patients with adult nephrotic syndrome.
Serum paraoxonase activity in familial hypercholesterolaemia and insulin-dependent diabetes mellitus.
Serum paraoxonase activity is associated with epicardial fat tissue in renal transplant recipients.
Serum paraoxonase activity is decreased in uremic patients.
Serum paraoxonase enzyme activity and oxidative stress in obese subjects.
Serum Paraoxonase Levels are Correlated with Impaired Aortic Functions in Patients with Chronic Kidney Disease.
Serum paraoxonase-1 (PON1) activities (PONase/AREase) and polymorphisms in patients with type 2 diabetes mellitus in a North-West Indian population.
Serum paraoxonase-1 gene polymorphism and enzyme activity in patients with urolithiasis.
Serum Paraoxonase-1 Levels are Significantly Decreased in the Presence of Insulin Resistance.
Shift of the interconnection from the reaction system of paraoxonase 1 to the peroxidation reaction system of myeloperoxidase with HDL-C levels: a marker of atherosclerosis in patients with normal cholesterol levels.
Some cardiovascular therapeutics inhibit paraoxonase 1 (PON1) from human serum.
Some indazoles reduced the activity of human serum paraoxonase 1, an antioxidant enzyme: in vitro inhibition and molecular modeling studies.
Sonographic evaluation of atherosclerosis burden in carotid arteries of ischemic stroke patients and its relation to paraoxonase 1 and 2, MTHFR and AT1R genetic variants.
Studies on protective effects of human paraoxonases 1 and 3 on atherosclerosis in apolipoprotein E knockout mice.
Study on molecular mechanisms of nattokinase in pharmacological action based on label-free liquid chromatography-tandem mass spectrometry.
Synergism between apolipoprotein E ?4 allele and paraoxonase (PON1) 55-M allele is associated with risk of systemic lupus erythematosus.
Synergistic effect of polymorphisms of paraoxonase gene cluster and arsenic exposure on electrocardiogram abnormality.
Targeting paraoxonase-1 in atherosclerosis.
The associations between serum paraoxonase 1 activity and carotid atherosclerosis in renal transplant patients.
The behaviour of some antihypertension drugs on human serum paraoxonase-1: an important protector enzyme against atherosclerosis.
The correlation of homocysteine-thiolactonase activity of the paraoxonase (PON1) protein with coronary heart disease status.
The effect of atorvastatin therapy on lecithin:cholesterol acyltransferase, cholesteryl ester transfer protein and the antioxidant paraoxonase.
The effect of HDL-bound and free PON1 on copper-induced LDL oxidation.
The Gln/Arg polymorphism of human paraoxonase (PON 192) is not related to myocardial infarction in the ECTIM Study.
The growing importance of PON1 in cardiovascular health: a review.
The Human Paraoxonase Gene Cluster as a Target in the Treatment of Atherosclerosis.
The human paraoxonase-1 phenotype modifies the effect of statins on paraoxonase activity and lipid parameters.
The paraoxonase gene family and atherosclerosis.
The paraoxonase gene family and coronary heart disease.
The paraoxonase gene polymorphism in stroke patients and lipid profile.
The relationship between lipoprotein-associated phospholipase A2 with cardiovascular risk factors in testosterone deficiency.
The role of cholesterol-enriched diet and paraoxonase 1 inhibition in atherosclerosis progression.
The synergistic inhibition of atherogenesis in apoE-/- mice between pravastatin and the sPLA2 inhibitor varespladib (A-002).
Ticagrelor induces paraoxonase-1 (PON1) and better protects hypercholesterolemic mice against atherosclerosis compared to clopidogrel.
Tobacco smoking modifies association between Gln-Arg192 polymorphism of human paraoxonase gene and risk of myocardial infarction.
Treatment of atherosclerosis by transplantation of bone endothelial progenitor cells over-expressed paraoxonase-1 gene by recombinant adeno-associated virus in rat.
Urokinase-type plasminogen activator downregulates paraoxonase 1 expression in hepatocytes by stimulating peroxisome proliferator-activated receptor-? nuclear export.
Variation in paraoxonase-1 activity and atherosclerosis.
[Biochemical studies on experimental atherosclerosis of the rabbit. Cholinesterases and arylesterase in the plasma and aortic wall. I. Technics and results in normal rabbits]
[Biochemical studies on experimental atherosclerosis of the rabbit. Cholinesterases and arylesterase in the plasma and aortic wall. II. Results in a rabbit given an atherogenic diet]
[Cholesterol oxidation, macrophage foam cells and atherosclerosis: importance of antioxidants and paraoxonase]
[From organophosphate compound toxicity to atherosclerosis: role of paraoxonase 1]
[The relation of serum paraoxonase-1 activity with isolated coronary artery ectasia: an observational study].
Autoimmune Diseases
Immunological manifestations in type I diabetic children.
The Antioxidant Role of Paraoxonase 1 and Vitamin E in Three Autoimmune Diseases.
Babesiosis
Plasma biomarkers of SIRS and MODS associated with canine babesiosis.
Relationship between paraoxonase 1 activity and high density lipoprotein concentration during naturally occurring babesiosis in dogs.
Bacteriuria
Erratum to: Preliminary study on serum paraoxonase-1 status and chemokine (C-C motif) ligand 2 in hospitalized elderly patients with catheter-associated asymptomatic bacteriuria.
Preliminary study on serum paraoxonase-1 status and chemokine (C-C motif) ligand 2 in hospitalized elderly patients with catheter-associated asymptomatic bacteriuria.
Behcet Syndrome
Paraoxonase and Arylesterase Levels in Behcet's Disease and Their Relations with the Disease Activity.
Purification of Paraoxonase Enzyme From the Sera of Patients with Behcet's Disease and Analyzing the Effects of the Drugs Containing Imuran (Azathioprine), Prednisolone (Methylprednisolone) and Colchium (Colchicine).
beta-Thalassemia
Oxidative status and serum PON1 activity in beta-thalassemia minor.
Paraoxonase and arylesterase activity with oxidative status in children with thalassemia major.
Paraoxonase and platelet-activating factor acetylhydrolase activities in lipoproteins of beta-thalassemia/hemoglobin E patients.
Blindness
Serum paraoxonase 1 activity and lipid peroxidation levels in patients with age-related macular degeneration.
Bone Diseases, Metabolic
Paraoxonase-1 activity as a marker of atherosclerosis is not associated with low bone mineral density in healthy postmenopausal women.
Brain Neoplasms
Risk of brain tumors in children and susceptibility to organophosphorus insecticides: the potential role of paraoxonase (PON1).
Breast Neoplasms
Association of L55M and Q192R polymorphisms in paraoxonase 1 (PON1) gene with breast cancer risk and their clinical significance.
Association of polymorphisms in the paraoxonase 1 gene with breast cancer incidence in the CPS-II Nutrition Cohort.
Association of PON1, LEP and LEPR Polymorphisms with Susceptibility to Breast Cancer: A Meta-Analysis.
Association of Serum Paraoxonase 1 Activities, Polymorphisms and Oxidative Stress in Breast Cancer Patients with Type 2 Diabetes Mellitus.
Effect of radiotherapy on activity and concentration of serum paraoxonase-1 in breast cancer patients.
Genetic Polymorphisms of Paraoxonase 1 (PON1) Gene: Association Between L55M or Q192R with Breast Cancer Risk and Clinico-Pathological Parameters.
Liver X Receptor (LXR)-regulated Genes of Cholesterol Trafficking and Breast Cancer Severity.
Paired measurement of serum amyloid A (SAA) and paraoxonase 1 (PON1) as useful markers in breast cancer recurrence.
Paraoxonase 1 (PON1) as a marker of short term death in breast cancer recurrence.
Paraoxonase 1 gene polymorphisms are associated with an increased risk of breast cancer in a population of Chinese women.
Paraoxonase 1 genetic polymorphisms and susceptibility to breast cancer: A meta-analysis.
Polymorphisms in three obesity-related genes (LEP, LEPR, and PON1) and breast cancer risk: a meta-analysis.
Serum paraoxonase and arylesterase can be useful markers to predict neoadjuvant chemotherapy requirement in patients with breast cancer.
Bronchiectasis
Total oxidant and antioxidant status and paraoxonase 1 levels of children with noncystic fibrosis bronchiectasis
Calcinosis
Oxidative and antioxidant changes during formation of unstable atherosclerotic plaque.
Carcinoma
192R allele of paraoxanase 1 (PON1) gene as a new marker for susceptibility to bladder cancer.
Acute phase proteins and biomarkers of oxidative status in feline spontaneous malignant mammary tumours.
Arylesterase in serum: elaboration and clinical application of a fixed-incubation method.
Assessment of PPARGC1A, PPARGC1B, and PON1 Genetic Polymorphisms in Esophageal Squamous Cell Carcinoma Susceptibility in the Eastern Chinese Han Population: A Case-Control Study Involving 2351 Subjects.
Genetic polymorphisms in the Paraoxonase 1 gene and risk of ovarian epithelial carcinoma.
Investigating paraoxonase-1 gene Q192R and L55M polymorphism in patients with renal cell cancer.
Serum paraoxonase-1 enzyme activities and oxidative stress levels in patients with esophageal squamous cell carcinoma.
Carcinoma, Hepatocellular
Amphenicol and Macrolide Derived Antibiotics Inhibit Paraoxonase Enzyme Activity in Human Serum and Human Hepatoma Cells (HepG2) in vitro.
Arylesterase isoenzymes and activity in normal healthy adults and in patients with cancer and with other diseases.
Differential effects of some antibiotics on paraoxonase enzyme activity on human hepatoma cells (HepG2) in vitro.
Effect of lipoic acid on paraoxonase-1 and paraoxonase-3 protein levels, mRNA expression and arylesterase activity in liver hepatoma cells.
Evaluation of the prognostic value of paraoxonase 1 in the recurrence and metastasis of hepatocellular carcinoma and establishment of a liver-specific predictive model of survival.
Hypermethylation reduces the expression of PNPLA7 in hepatocellular carcinoma.
Lead inhibits paraoxonase 2 but not paraoxonase 1 activity in human hepatoma HepG2 cells.
Quantitative Proteomic Analysis Identified Paraoxonase 1 as a Novel Serum Biomarker for Microvascular Invasion in Hepatocellular Carcinoma.
Serum fucosylated paraoxonase 1 as a potential glycobiomarker for clinical diagnosis of early hepatocellular carcinoma using ELISA Index.
Carcinoma, Non-Small-Cell Lung
Association of genetic polymorphisms in the paraoxonase 1 gene with the risk and prognosis of non-small cell lung cancer in chinese han population.
Carcinoma, Ovarian Epithelial
Genetic polymorphisms in the Paraoxonase 1 gene and risk of ovarian epithelial carcinoma.
Serum paraoxonase and arylesterase activities in patients with epithelial ovarian cancer.
Carcinoma, Renal Cell
Investigating paraoxonase-1 gene Q192R and L55M polymorphism in patients with renal cell cancer.
Cardiomegaly
Human paraoxonase gene cluster overexpression alleviates angiotensin II-induced cardiac hypertrophy in mice.
Cardiomyopathies
A Genetic Biomarker of Oxidative Stress, the Paraoxonase-1 Q192R Gene Variant, Associates with Cardiomyopathy in CKD: A Longitudinal Study.
FGF21 ameliorates diabetic cardiomyopathy by activating the AMPK-paraoxonase 1 signaling axis in mice.
Cardiotoxicity
Propolis relieves the cardiotoxicity of chlorpyrifos in diabetic rats via alleviations of paraoxonase-1 and xanthine oxidase genes expression.
Cardiovascular Diseases
A half-marathon and a marathon run induce oxidative DNA damage, reduce antioxidant capacity to protect DNA against damage and modify immune function in hobby runners.
A meta-analysis on relationship between paraoxonase 1 polymorphisms and atherosclerotic cardiovascular diseases.
A new method for the determination of arylesterase activity in human serum using simulated body fluid.
A paraoxonase gene polymorphism, PON 1 (55), as an independent risk factor for increased carotid intima-media thickness in middle-aged women.
A variant of paraoxonase (PON1) gene is associated with diabetic retinopathy in IDDM.
Activity of Antioxidant Enzymes and Their Association with Lipid Profile in Mexican People without Cardiovascular Disease: An Analysis of Interactions.
Additional Common Polymorphisms in the PON Gene Cluster Predict PON1 Activity but Not Vascular Disease.
Alterations of HDL Particles in Children with End-stage Renal Disease.
An improved polymerase chain reaction-restriction fragment length polymorphism assay for the detection of a PON2 gene polymorphism.
Arylesterase activity and antioxidant status depend on PON1-Q192R and PON1-L55M polymorphisms in subjects with increased risk of cardiovascular disease consuming walnut-enriched meat.
Arylesterase activity is associated with antioxidant intake and paraoxonase-1 (PON1) gene methylation in metabolic syndrome patients following an energy restricted diet.
Association of carotid intima media thickness with atherogenic index of plasma, apo B/apo A-I ratio and paraoxonase activity in patients with non-alcoholic fatty liver disease.
Association of lead, cadmium and mercury with paraoxonase 1 activity and malondialdehyde in a general population in Southern Brazil.
Association of oxidative stress and paraoxonase status with PROCAM risk score.
Association of Paraoxonase 1 Polymorphism and Serum 25-Hydroxyvitamin D with the Risk of Cardiovascular Disease in Patients with Rheumatoid Arthritis.
Astaxanthin prevents changes in the activities of thioredoxin reductase and paraoxonase in hypercholesterolemic rabbits.
Carotid artery intima media thickness associates with skin autofluoresence in non-diabetic subjects without clinically manifest cardiovascular disease.
Codon 311 (Cys --> Ser) polymorphism of paraoxonase-2 gene is associated with apolipoprotein E4 allele in both Alzheimer's and vascular dementias.
Common paraoxonase gene variants, mortality risk and fatal cardiovascular events in elderly subjects.
Dietary Selenium (Se) and Vitamin E (V(E)) Supplementation Modulated Methylmercury-Mediated Changes in Markers of Cardiovascular Diseases in Rats.
Downregulation of paraoxonase 3 contributes to aggressive human hepatocellular carcinoma progression and associates with poor prognosis.
Effect of efavirenz on high-density lipoprotein antioxidant properties in HIV-infected patients.
Effect of rosuvastatin versus atorvastatin treatment on paraoxonase-1 activity in men with established cardiovascular disease and a low HDL-cholesterol.
Effect of statin therapy on paraoxonase-1 status: A systematic review and meta-analysis of 25 clinical trials.
Effects of Calcineurin Inhibitors on Paraoxonase and Arylesterase Activity After a Kidney Transplant.
Effects of Iron Supplementation With and Without Docosahexaenoic Acid on the Cardiovascular Disease Risk Based on Paraoxonase-1, hs-CRP, and ApoB/ApoA-I Ratio in Women with Iron Deficiency Anemia.
Effects of red wine consumption on serum paraoxonase/arylesterase activities and on lipoprotein oxidizability in healthy-men.
Effects of selenium supplementation on paraoxonase-1 and myeloperoxidase activity in subjects with cardiovascular disease: the Selenegene study, a double-blind randomized controlled trial.
Exogenous (Pomegranate Juice) or Endogenous (Paraoxonase1) Antioxidants Decrease Triacylglycerol Accumulation in Mouse Cardiovascular Disease-Related Tissues.
Factors Associated with Paraoxonase Genotypes and Activity in a Diverse, Young, Healthy Population: The Coronary Artery Risk Development in Young Adults (CARDIA) Study.
Functional genomic of the paraoxonase (PON1) polymorphisms: effects on pesticide sensitivity, cardiovascular disease, and drug metabolism.
Genetic and environmental determinants of the PON-1 phenotype.
Genetic factors associated with the absence of atherosclerosis in octogenarians.
Genotype and phenotype of salt-stimulated paraoxonase 1 (PON1) is associated with atherogenic indices in type 2 diabetes.
HDL associated paraoxonase-1 activity correlates with systemic inflammation, disease activity and cardiovascular risk factors in psoriatic disease.
HDL-Associated Paraoxonase 1 as a Bridge between Postmenopausal Osteoporosis and Cardiovascular Disease.
HDL3-related decreased serum paraoxonase (PON) activity in uremic patients: comparison with the PON1 allele polymorphism.
Homocysteine threshold value based on cystathionine beta synthase and paraoxonase 1 activities in mice.
Hypertension in children (12-14 years)--a case-control study in Bursa, Turkey.
Incident type 2 diabetes is associated with HDL, but not with its anti-oxidant constituent - paraoxonase-1: The prospective cohort PREVEND study.
Indications that paraoxonase-1 contributes to plasma high density lipoprotein levels in familial hypercholesterolemia.
Indices of paraoxonase and oxidative status do not enhance the prediction of subclinical cardiovascular disease in mixed-ancestry South Africans.
Induction of the paraoxonase-1 gene expression by resveratrol.
Influence of Human Paraoxonase-1 Polymorphism (Q192R) on Serum Levels of Clinical Biomarkers Indicatives of Cardiovascular Diseases Risk in Mexican Women.
Interaction between polyphenols intake and PON1 gene variants on markers of cardiovascular disease: a nutrigenetic observational study.
Interaction of folate intake and the paraoxonase Q192R polymorphism with risk of incident coronary heart disease and ischemic stroke: the atherosclerosis risk in communities study.
Low Serum Paraoxonase-1 Activity Associates with Incident Cardiovascular Disease Risk in Subjects with Concurrently High Levels of High-Density Lipoprotein Cholesterol and C-Reactive Protein.
Lower paraoxonase 1 activity in Tunisian bipolar I patients.
Methylmercury exposure, PON1 gene variants and serum paraoxonase activity in Eastern James Bay Cree adults.
Myeloperoxidase and paraoxonase-1 in type 2 diabetic patients.
Naphthoquinones, benzoquinones, and anthraquinones: Molecular docking, ADME and inhibition studies on human serum paraoxonase-1 associated with cardiovascular diseases.
No influence of increased intake of orange and blackcurrant juices and dietary amounts of vitamin E on paraoxonase-1 activity in patients with peripheral arterial disease.
No or only population-specific effect of PON1 on human longevity: A comprehensive meta-analysis.
Ocular distribution of antioxidant enzyme paraoxonase & its alteration in cataractous lens & diabetic retina.
Oxidative status and prevalent cardiovascular disease in patients with chronic renal failure treated by hemodialysis.
Paraoxonase (PON1) and the risk for coronary heart disease and myocardial infarction in a general population of Dutch women.
Paraoxonase 1 (PON1) Q192R genotypes and their interaction with smoking strongly increase atherogenicity and the Framingham risk score.
Paraoxonase 1 activity as a predictor of cardiovascular disease in type 2 diabetes.
Paraoxonase 1 activity in subchronic low-level inorganic arsenic exposure through drinking water.
Paraoxonase 1 activity, concentration and genotype in cardiovascular disease.
Paraoxonase 1 concerning dyslipidaemia, cardiovascular diseases, and mortality in haemodialysis patients.
Paraoxonase 1 Gene L55M Polymorphism and Paraoxonase 1 Activity in Obstructive Sleep Apnea Patients.
Paraoxonase 1 gene polymorphisms and dementia in humans.
Paraoxonase 1 Phenotype and Protein N-Homocysteinylation in Patients with Rheumatoid Arthritis: Implications for Cardiovascular Disease.
Paraoxonase 192 polymorphism and its relationship to serum lipids in Turkish renal transplant recipients.
Paraoxonase activity in athletic adolescents.
Paraoxonase activity in high-density lipoproteins: a comparison between healthy and obese females.
Paraoxonase and arylesterase activities in children with iron deficiency anemia and vitamin B12 deficiency anemia.
Paraoxonase and arylesterase activities in coronary artery disease.
Paraoxonase and arylesterase activities in dipper and non-dipper prehypertensive subjects.
Paraoxonase and arylesterase activities in patients with cardiac syndrome X, and their relationship with oxidative stress markers.
Paraoxonase and arylesterase activities in untreated dipper and non-dipper hypertensive patients.
Paraoxonase and atherosclerosis-related cardiovascular diseases.
Paraoxonase as a risk marker for cardiovascular disease: facts and hypotheses.
Paraoxonase genotype and carotid intima-media thickness in children with familial hypercholesterolemia.
Paraoxonase levels in women with polycystic ovary syndrome.
Paraoxonase polymorphism Met-Leu54 is associated with modified serum concentrations of the enzyme. A possible link between the paraoxonase gene and increased risk of cardiovascular disease in diabetes.
Paraoxonase polymorphisms are not associated with cardiovascular risk in renal transplant recipients.
Paraoxonase-1 gene Q192R and L55M polymorphisms and risk of cardiovascular disease in Egyptian patients with type 2 diabetes mellitus.
Paraoxonase2 C311S polymorphism and low levels of HDL contribute to a higher mortality risk after acute myocardial infarction in elderly patients.
Paraoxonase: another factor in NIDDM cardiovascular disease.
Pharmacological interactions of paraoxonase 1 (PON1): A HDL-bound antiatherogenic enzyme.
Phenol-enriched olive oils modify paraoxonase-related variables: A randomized, crossover, controlled trial.
Polymorphisms of human paraoxonase 1 gene (PON1) and susceptibility to diabetic nephropathy in type I diabetes mellitus.
PON3 is upregulated in cancer tissues and protects against mitochondrial superoxide-mediated cell death.
PONI and its association with oxidative stress in type I and type II diabetes mellitus.
Population differences in DNA sequence variation and linkage disequilibrium at the PON1 gene.
Preferential inhibition of paraoxonase activity of human paraoxonase 1 by negatively charged lipids.
Preservation of paraoxonase activity by wine flavonoids: possible role in protection of LDL from lipid peroxidation.
Review: The role of paraoxonase in cardiovascular diseases.
Salt overload in fructose-fed insulin-resistant rats decreases paraoxonase-1 activity.
Serum Levels of Anti-PON1 and Anti-HDL Antibodies as Potential Biomarkers of Premature Atherosclerosis in Systemic Lupus Erythematosus.
Serum paraoxonase-1 activity and risk of incident cardiovascular disease: The PREVEND study and meta-analysis of prospective population studies.
Serum paraoxonase-1 activity is associated with light to moderate alcohol consumption: the PREVEND cohort study.
Serum paraoxonase-1 activity is inversely related to free thyroxine in euthyroid subjects: The PREVEND Cohort Study.
Sex difference: an important issue to consider in epidemiological and clinical studies dealing with serum paraoxonase-1.
Solubilization and humanization of paraoxonase-1.
The epigenetic regulation of paraoxonase 1 (PON1) as an important enzyme in HDL function: The missing link between environmental and genetic regulation.
The paraoxonase Leu-Met54 and Gln-Arg191 gene polymorphisms are not associated with the risk of coronary heart disease.
The role of paraoxonase 1 activity in cardiovascular disease: potential for therapeutic intervention.
Carotid Artery Diseases
Evaluation of single nucleotide polymorphisms in 6 candidate genes and carotid intima-media thickness in community-dwelling residents.
Genetic factors associated with the absence of atherosclerosis in octogenarians.
Paraoxonase activity, but not haplotype utilizing the linkage disequilibrium structure, predicts vascular disease.
Paraoxonase genotype, LDL-oxidation and carotid atherosclerosis in male life-long smokers.
Paraoxonase PON1 polymorphism leu-Met54 is associated with carotid atherosclerosis: results of the Austrian Stroke Prevention Study.
Paraoxonase-1 and Symptomatic Status in Carotid Artery Disease.
Paraoxonase-1: Characteristics and role in atherosclerosis and carotid artery disease.
Relationship between high-density lipoprotein paraoxonase gene M/L55 polymorphism and carotid atherosclerosis differs in smoking and nonsmoking men.
The relationship between serum paraoxonase levels and carotid atherosclerotic plaque formation in Alzheimer's patients.
Carotid Stenosis
Polymorphisms in the PON gene cluster are associated with Alzheimer disease.
The Association of Paraoxonase-1 Polymorphism with Carotid Artery Stenosis among Elderly Chinese Population.
Cataract
Assessment of paraoxonase activity and lipid peroxidation levels in diabetic and senile subjects suffering from cataract.
Expression and activity of paraoxonase 1 in human cataractous lens tissue.
Paraoxonase-1 is associated with corneal endothelial cell alterations in patients with chronic obstructive pulmonary disease.
Q192R paraoxonase1 polymorphism is a risk factor for cataract in Pakistani population.
Celiac Disease
Lipid peroxidation and paraoxonase-1 activity in celiac disease.
The Role of Oxidative Stress in the Etiopathogenesis of Gluten-sensitive Enteropathy Disease.
Cerebral Amyloid Angiopathy
No association of paraoxonase genotype or atherosclerosis with cerebral amyloid angiopathy.
Cerebral Hemorrhage
Association Between Paraoxonase Gene Polymorphisms and Intracerebral Hemorrhage in a Korean Population.
Lack of association between the paraoxonase 1 Q/R192 single nucleotide polymorphism and stroke in a Chinese cohort.
Cerebral Infarction
Lack of association between the paraoxonase 1 Q/R192 single nucleotide polymorphism and stroke in a Chinese cohort.
Paraoxonase1 polymorphism Leu-Met55 is associated with cerebral infarction in Japanese population.
PON1 Hypermethylation and PON3 Hypomethylation are Associated with Risk of Cerebral Infarction.
Role of Paraoxonase 1 Activity and Oxidative/Antioxidative Stress Markers in Patients with Acute Cerebral Infarction.
Cerebrovascular Disorders
An improved polymerase chain reaction-restriction fragment length polymorphism assay for the detection of a PON2 gene polymorphism.
Association between PON1 5'-regulatory region polymorphisms, PON1 activity and ischemic stroke.
Paraoxonase 1 192 Gln/Arg gene polymorphism and cerebrovascular disease: interaction with type 2 diabetes.
Polymorphism of apoprotein E (APOE), methylenetetrahydrofolate reductase (MTHFR) and paraoxonase (PON1) genes in patients with cerebrovascular disease.
Rare coding variation in paraoxonase-1 is associated with ischemic stroke in the NHLBI Exome Sequencing Project.
Cholecystolithiasis
A longitudinal analysis of alteration in lecithin-cholesterol acyltransferase and paraoxonase activities following laparoscopic cholecystectomy relative to other parameters of HDL function and the acute phase response.
Cholelithiasis
Evaluation of paraoxonase, malondialdehyde, and lipoprotein levels in patients with asymptomatic cholelithiasis.
Cholestasis, Intrahepatic
Placental ADAMTS-12 Levels in the Pathogenesis of Preeclampsia and Intrahepatic Cholestasis of Pregnancy.
Cholesteatoma
Oxidative stress in chronic otitis media.
Chorioamnionitis
Evaluation of Maternal Serum 25-Hydroxyvitamin D, Paraoxonase 1 Levels, and Neutrophil-to-Lymphocyte Ratio in Spontaneous Preterm Birth.
Choriocarcinoma
Adenocarcinoma of the colon with choriocarcinoma in its metastases.
Cleft Lip
Interactions between superoxide dismutase and paraoxonase polymorphic variants in nonsyndromic cleft lip with or without cleft palate in the Brazilian population.
Cleft Palate
Interactions between superoxide dismutase and paraoxonase polymorphic variants in nonsyndromic cleft lip with or without cleft palate in the Brazilian population.
Coinfection
Candida albicans increases the pathogenicity of Staphylococcus aureus during polymicrobial infection of Galleria mellonella larvae.
Colic
Menstruation distress is strongly associated with hormone-immune-metabolic biomarkers.
Colitis
Paraoxonase-1 suppresses experimental colitis via the inhibition of IFN-? production from CD4 T cells.
Colitis, Ischemic
Paraoxonase and arylesterase activities, lipid profile, and oxidative damage in experimental ischemic colitis model.
Colitis, Ulcerative
In vivo effects of curcumin on the paraoxonase, carbonic anhydrase, glucose-6-phosphate dehydrogenase and ?-glucosidase enzyme activities in dextran sulphate sodium-induced ulcerative colitis mice.
miR-155 targets Est-1 and induces ulcerative colitis via the IL-23/17/6-mediated Th17 pathway.
Paraoxonase (PON)1 192R allele carriage is associated with reduced risk of inflammatory bowel disease.
Paraoxonase-1 and arylesterase levels in patients with ulcerative colitis.
Paraoxonase-1 status in Crohn's disease and ulcerative colitis.
Serum paraoxonase 1 activity and malondialdehyde levels in patients with ulcerative colitis.
Colorectal Neoplasms
Changes in lecithin: cholesterol acyltransferase, cholesteryl ester transfer protein and paraoxonase-1 activities in patients with colorectal cancer.
Diagnostic value of thiols, paraoxonase 1, arylesterase and oxidative balance in colorectal cancer in human.
No association between genetic polymorphisms in NAD(P)H oxidase p22phox and paraoxonase 1 and colorectal cancer risk.
Paraoxonase-1 and arylesterase activities in patients with colorectal cancer.
Serum lipid hydroperoxide levels and paraoxonase activity in patients with lung, breast, and colorectal cancer.
Communicable Diseases
Effect of continuous renal-replacement therapy on paraoxonase-1-related variables in patients with acute renal failure caused by septic shock.
Congenital Abnormalities
Genetic polymorphism of paraoxonase 1 (PON1) and susceptibility to Parkinson's disease.
Coronary Artery Disease
A 192Arg variant of the human paraoxonase (HUMPONA) gene polymorphism is associated with an increased risk for coronary artery disease in the Japanese.
A preliminary study of human paraoxonase and PON 1 L/M55-PON 1 Q/R 192 polymorphisms in Turkish patients with coronary artery disease.
A prospective study of paraoxonase gene Q/R192 polymorphism and severity, progression and regression of coronary atherosclerosis, plasma lipid levels, clinical events and response to fluvastatin.
A variant of human paraoxonase/arylesterase (HUMPONA) gene is a risk factor for coronary artery disease.
Association between HDL particles size and myeloperoxidase/ paraoxonase-1 (MPO/PON1) ratio in patients with acute coronary syndrome.
Association between paraoxonase 1 activity and severity of coronary artery disease in patients with acute coronary syndromes.
Association between paraoxonase activity and lipid levels in patients with premature coronary artery disease.
Association between paraoxonase-1 activity and lipid peroxidation indicator levels in people living in the Antalya region with angiographically documented coronary artery disease.
Association between PON1 rs662 polymorphism and coronary artery disease.
Association between the paraoxonase-1 192Q>R allelic variant and coronary endothelial dysfunction in patients with early coronary artery disease.
Association between the severity of angiographic coronary artery disease and paraoxonase gene polymorphisms in the National Heart, Lung, and Blood Institute-sponsored Women's Ischemia Syndrome Evaluation (WISE) study.
Association of angiotensin-converting enzyme, methylene tetrahydrofolate reductase and paraoxonase gene polymorphism and coronary artery disease in an Indian population.
Association of elevated apoA-I glycation and reduced HDL-associated paraoxonase1, 3 activity, and their interaction with angiographic severity of coronary artery disease in patients with type 2 diabetes mellitus.
Association of genetic variants in Methylenetetrahydrofolate Reductase and Paraoxonase-1 genes with homocysteine, folate and vitamin B12 in coronary artery disease.
Association of lipids, lipoproteins, apolipoproteins and paraoxonase enzyme activity with premature coronary artery disease.
Association of paraoxonase-1 activity and concentration with angiographic severity and extent of coronary artery disease.
Association of paraoxonase-1 M55L genotype and alcohol consumption with coronary atherosclerosis: the Helsinki Sudden Death Study.
Association of paraoxonase1 gene Q192R polymorphism and apolipoprotein B in Asian Indian women with coronary artery disease risk.
Associations between genetic polymorphisms of paraoxonase genes and coronary artery disease in a Taiwanese population.
Both paraoxonase-1 genotype and activity do not predict the risk of future coronary artery disease; the EPIC-Norfolk Prospective Population Study.
Cigarette smoking is associated with dose-dependent adverse effects on paraoxonase activity and fibrinogen in young women.
Clinical and Genetic Association of Serum Paraoxonase and Arylesterase Activities With Cardiovascular Risk.
Combined impact of matrix metalloproteinase-3 and paraoxonase 1 55/192 gene variants on coronary artery disease in Turkish patients.
Common paraoxonase gene variants, mortality risk and fatal cardiovascular events in elderly subjects.
Coronary artery disease is associated with the ratio of apolipoprotein A-I/B and serum concentration of apolipoprotein B, but not with paraoxonase enzyme activity in Iranian subjects.
Coronary artery disease risk factors in patients with schizophrenia: effects of short term antipsychotic treatment.
Different pattern of association of paraoxonase Gln192-->Arg polymorphism with sporadic late-onset Alzheimer's disease and coronary artery disease.
Diminished serum paraoxonase activity in patients with coronary artery calcification.
Effects of cytochrome P450 2C19 and paraoxonase 1 polymorphisms on antiplatelet response to clopidogrel therapy in patients with coronary artery disease.
Effects of PON1 Gene Promoter DNA Methylation and Genetic Variations on the Clinical Outcomes of Dual Antiplatelet Therapy for Patients Undergoing Percutaneous Coronary Intervention.
Evaluation of the paraoxonases as candidate genes for stroke: Gln192Arg polymorphism in the paraoxonase 1 gene is associated with increased risk of stroke.
Frequency distribution of the single-nucleotide -108C/T polymorphism at the promoter region of the PON1 gene in Asian Indians and its relationship with coronary artery disease.
Gender-specific correlation between plasma myeloperoxidase levels and serum high-density lipoprotein-associated paraoxonase-1 levels in patients with stable and unstable coronary artery disease.
Genetic polymorphism in paraoxonase is a risk factor for childhood focal segmental glomerulosclerosis.
Genetic variations of the paraoxonase gene in patients with coronary artery disease.
Genotypes of Common Polymorphisms in the PON1 Gene Associated with Paraoxonase Activity as Cardiovascular Risk Factor.
Glycation impairs high-density lipoprotein function.
High prevalence of low serum paraoxonase-1 in subjects with coronary artery disease.
Human paraoxonase gene cluster overexpression alleviates angiotensin II-induced cardiac hypertrophy in mice.
Human paraoxonase gene polymorphisms and coronary artery disease risk.
Hyperhomocysteinemia, paraoxonase activity and risk of coronary artery disease.
Improved risk assessment of coronary artery disease by substituting paraoxonase 1 activity for HDL-C: Novel cardiometabolic biomarkers based on HDL functionality.
Inhibitory effect of the paraoxonase gene on the formation of rabbit coronary atherosclerosis.
Interaction of paraoxonase-192 polymorphism with low HDL-cholesterol in coronary artery disease risk.
Isolation and complete covalent structure of liver microsomal paraoxonase.
Low paraoxonase 1 arylesterase activity and high von Willebrand factor levels are associated with severe coronary atherosclerosis in patients with non-diabetic stable coronary artery disease.
Low serum paraoxonase1 activity levels predict coronary artery disease severity.
Low serum PON1 activity: An independent risk factor for coronary artery disease in North-West Indian type 2 diabetics.
Mutations in the human paraoxonase 1 gene: frequencies, allelic linkages, and association with coronary artery disease.
Oxidation and endothelial dysfunction biomarkers of atherosclerotic plaque instability. Studies of the vascular wall and blood.
Oxidized-LDL and Paraoxonase-1 as biomarkers of Coronary Artery Disease in Patients with Sleep-Disordered Breathing.
Paraoxonase (PON1) activity in north west Indian Punjabis with coronary artery disease & type 2 diabetes mellitus.
Paraoxonase 1 gene (Q192R) polymorphism confers susceptibility to coronary artery disease in type 2 diabetes patients: Evidence from case-control studies.
Paraoxonase 1 gene polymorphisms and enzyme activities in coronary artery disease and its relationship to serum lipids and glycemia.
Paraoxonase 1 gene polymorphisms contribute to coronary artery disease risk among north Indians.
Paraoxonase 1 gene polymorphisms in angiographically assessed coronary artery disease: evidence for gender interaction among Brazilians.
Paraoxonase 1 polymorphisms and ischemic stroke risk: A systematic review and meta-analysis.
Paraoxonase 192 Gln/Arg gene polymorphism, coronary artery disease, and myocardial infarction in type 2 diabetes.
Paraoxonase 3: Structure and Its Role in Pathophysiology of Coronary Artery Disease.
Paraoxonase activity following exercise-based cardiac rehabilitation program.
Paraoxonase activity in human pericardial fluid: its relationship to coronary artery disease.
Paraoxonase and arylesterase activities in coronary artery disease.
Paraoxonase and arylesterase activities in stent restenosis in bare metal stent.
Paraoxonase Arg 192 allele is an independent risk factor for three-vessel stenosis of coronary artery disease.
Paraoxonase gene polymorphism and coronary artery disease in Indian subjects.
Paraoxonase promoter polymorphism T(-107)C and relative paraoxonase deficiency as determinants of risk of coronary artery disease.
Paraoxonase variants relate to 10-year risk in coronary artery disease: impact of a high-density lipoprotein-bound antioxidant in secondary prevention.
Paraoxonase-1 (PON1) activity, but not PON1(Q192R) phenotype, is a predictor of coronary artery disease in a middle-aged Serbian population.
Paraoxonase-1 activity and pleiotropic properties of simvastatin in obese and non-obese patients with stable coronary artery disease (CAD).
Paraoxonase-1 and Simvastatin Treatment in Patients with Stable Coronary Artery Disease.
Paraoxonase-1 Q192R polymorphism and its association with hs-CRP and fasting blood glucose levels and risk of coronary artery disease.
Paraoxonase1, its Q192R polymorphism and HDL-cholesterol in relation to intensive cardiac care unit stay in ischemic heart disease.
Polymorphisms in the PON gene cluster are associated with Alzheimer disease.
PON gene polymorphisms and ischaemic stroke: a systematic review and meta analysis.
PON-1 Activity and Plasma 8-Isoprostane Concentration in Patients with Angiographically Proven Coronary Artery Disease.
PON1 activity is inversely related to LDL apoB carbonyl content in patients with coronary artery disease.
Q192R polymorphism in the PON1 gene and familial hypercholesterolemia in a Saudi population.
R/R genotype of human paraoxonase (PON1) is more protective against lipoprotein oxidation and coronary artery disease in Japanese subjects.
Reduced paraoxonase 1 activity as a marker for severe coronary artery disease.
Relation between butyrylcholinesterase K variant, paraoxonase 1 (PON1) Q and R and apolipoprotein E epsilon 4 genes in early-onset coronary artery disease.
Relationship between paraoxonase-1 (PON1) activity and lipoprotein (a) levels in Turkish coronary artery disease patients living in the Antalya region.
Relationship between rs854560
Relationship of microRNA 616 gene polymorphism with prognosis of patients with premature coronary artery disease.
Relationship of PON1 192 and 55 gene polymorphisms to calcific valvular aortic stenosis.
Smoking-dependent association between paraoxonase 1 M/L55 genotype and coronary atherosclerosis in males: an autopsy study.
Strawberries Added to the Usual Diet Suppress Fasting Plasma Paraoxonase Activity and Have a Weak Transient Decreasing Effect on Cholesterol Levels in Healthy Nonobese Subjects.
Synergism between paraoxonase Arg 192 and the angiotensin converting enzyme D allele is associated with severity of coronary artery disease.
Synergistic effects between Q192R polymorphism of paraoxonase 1 gene and some conventional risk factors in premature coronary artery disease.
The association of paraoxonase 1 gene L55M polymorphism with the extent and severity of coronary artery disease in the Turkish population and its dependence on gender.
The combined utility of myeloperoxidase (MPO) and paraoxonase 1 (PON1) as two important HDL-associated enzymes in coronary artery disease: Which has a stronger predictive role?
The Gln-Arg 191 polymorphism of the human paraoxonase gene is not associated with the risk of coronary artery disease among Chinese in Taiwan.
The Gln-Arg191 polymorphism of the human paraoxonase gene (HUMPONA) is not associated with the risk of coronary artery disease in Finns.
The gln-Arg192 polymorphism of human paraoxonase gene is not associated with coronary artery disease in italian patients.
The human paraoxonase Gln-Argl92 (Q/R) polymorphism in turkish patients with coronary artery disease.
The Q192R polymorphism of the paraoxonase 1 gene is a risk factor for coronary artery disease in Saudi subjects.
The relationship between paraoxonase-1 activity and coronary artery disease in patients with metabolic syndrome.
The risk of coronary artery disease in population of Taiwan is associated with Cys-Ser 311 polymorphism of human paraoxonase (PON)-2 gene.
The role of paraoxonase (PON) enzyme in the extent and severity of the coronary artery disease in type-2 diabetic patients.
The Role of Paraoxonase 1 (PON1) Gene Polymorphisms in Coronary Artery Disease: A Systematic Review and Meta-Analysis.
Tobacco smoking, paraoxonase-1 (PON1) activity and pleiotropic effects of simvastatin treatment in patients with stable coronary artery disease (CAD).
Two- and three-locus haplotypes of the paraoxonase (PON1) gene are associated with coronary artery disease in Asian Indians.
[Low paraoxonase and arylesterase plasma activities in Mexican patients with coronary artery disease]
[Relationship between paraoxonase 1 55 Met/Leu, paraoxonase 2 148 Ala/Gly genetic polymorphisms and coronary artery disease]
[Smoking enhances the decrease of adiponectin level in patients with coronary artery disease, carriers of MTHFR 677T and PON1 55M alleles].
[The relation of serum paraoxonase-1 activity with isolated coronary artery ectasia: an observational study].
[The role of myeloperoxidase, paraoxonase and nitric oxide system in blood and pericardial fluid in patients with IHD who underwent direct myocardial revascularization.]
Coronary Disease
Allelic variants of the human scavenger receptor class B type 1 and paraoxonase 1 on coronary heart disease: genotype-phenotype correlations.
An alternative pseudolikelihood method for multivariate random-effects meta-analysis.
Association Between Paraoxonase 2 Ser311Cys Polymorphism and Coronary Heart Disease Risk: A Meta-Analysis.
Associations of HDL phospholipids and paraoxonase activity with coronary heart disease in postmenopausal women.
Associations of the PON1 rs662 polymorphism with circulating oxidized low-density lipoprotein and lipid levels: a systematic review and meta-analysis.
Autopsy and postmortem examination case study on genetic risk factors for cardiac death: polymorphisms of endothelial nitric oxide synthase gene Glu298Asp variant and T-786C mutation, human paraoxonase 1 (PON1) gene and alpha2beta-adrenergic receptor gene.
Characterization of paraoxonase activity in pericardial fluid: usefulness as a marker of coronary disease.
Codon 311 (Cys --> Ser) polymorphism of paraoxonase-2 gene is associated with apolipoprotein E4 allele in both Alzheimer's and vascular dementias.
Diabetes mellitus and the late complications: influence of the genetic factors.
Differential effects of smoking on myocardial infarction risk according to the Gln/Arg 192 variants of the human paraoxonase gene.
Distribution of paraoxon hydrolytic activity in the serum of patients after myocardial infarction.
DNA polymorphisms in two paraoxonase genes (PON1 and PON2) are associated with the risk of coronary heart disease.
Do PON1-Q192R and PON1-L55M polymorphisms modify the effects of hypoxic training on paraoxonase and arylesterase activity?
Does paraoxonase play a role in susceptibility to cardiovascular disease?
Effect of statin therapy on plasma high-density lipoprotein-cholesterol levels is modified by paraoxonase 1 in Chinese patients with coronary heart disease.
Four genetic polymorphisms of paraoxonase gene and risk of coronary heart disease: a meta-analysis based on 88 case-control studies.
Four paraoxonase gene polymorphisms in 11212 cases of coronary heart disease and 12786 controls: meta-analysis of 43 studies.
Gene:environment interaction in lipid metabolism and effect on coronary heart disease risk.
Genetic polymorphism of paraoxonase and the risk of coronary heart disease.
Genetic variation in the paraoxonase-3 (PON3) gene is associated with serum PON1 activity.
Gln-Arg192 polymorphism of paraoxonase and coronary heart disease in type 2 diabetes.
High C-reactive protein and low paraoxonase1 in diabetes as risk factors for coronary heart disease.
High-density lipoprotein cholesterol and paraoxonase 1 (PON1) genetics and serum PON1 activity in prepubertal children in Spain.
Human paraoxonase 1 gene polymorphisms and the risk of coronary heart disease: a community-based study.
Human paraoxonase gene cluster polymorphisms as predictors of coronary heart disease risk in the prospective Northwick Park Heart Study II.
Inflammatory biomarkers and the prediction of coronary events among people at intermediate risk: the EPIC-Norfolk prospective population study.
Interaction effects between Paraoxonase 1 variants and cigarette smoking on risk of coronary heart disease in a Singaporean Chinese population.
Interaction of folate intake and the paraoxonase Q192R polymorphism with risk of incident coronary heart disease and ischemic stroke: the atherosclerosis risk in communities study.
LL-paraoxonase genotype is associated with a more severe degree of homeostasis model assessment IR in healthy subjects.
Mercury, eicosapentanoic acid and docosahexaenoic acid demonstrate limited effect on plasma paraoxonase-1 activity and blood pressure among avid seafood consumers in the Long Island Study of Seafood Consumption, NY, USA.
Molecular characterization and expression analysis of the porcine paraoxonase 3 (PON3) gene.
New chemiluminescent substrates of paraoxonase 1 with improved specificity: synthesis and properties.
Paraoxonase (PON1) and the risk for coronary heart disease and myocardial infarction in a general population of Dutch women.
Paraoxonase 1 (Q192R) gene polymorphism, coronary heart disease and the risk of a new acute coronary event.
Paraoxonase 1 activity, concentration and genotype in cardiovascular disease.
Paraoxonase 1 Activity, Lipid Profile, and Atherogenic Indexes Status in Coronary Heart Disease.
Paraoxonase 1 Activity, Polymorphism and Atherosclerosis Risk Factors in Patients Undergoing Coronary Artery Surgery.
Paraoxonase 1 Polymorphisms and Risk of Myocardial Infarction in Women and Men.
Paraoxonase 1 polymorphisms and survival.
Paraoxonase 1 polymorphisms as the risk factor of coronary heart disease in a Thai population.
Paraoxonase activity and coronary heart disease risk in healthy middle-aged males: the PRIME study.
Paraoxonase activity in two healthy populations with differing rates of coronary heart disease.
Paraoxonase activity is dramatically decreased in patients positive for anticardiolipin antibodies.
Paraoxonase and coronary heart disease risk: language misleads, linkage misinforms, function clarifies.
Paraoxonase and coronary heart disease.
Paraoxonase and other coronary risk factors in a community-based cohort.
Paraoxonase gene cluster variations associated with coronary heart disease in Chinese Han women.
Paraoxonase gene polymorphism and serum activity in progressive IgA nephropathy.
Paraoxonase gene polymorphism in Japanese subjects with coronary heart disease.
Paraoxonase gene Q192R & L55M polymorphisms in Indians with acute myocardial infarction & association with oxidized low density lipoprotein.
Paraoxonase Gln-Arg(192) and Leu-Met(55) gene polymorphisms and enzyme activity in a population with a low rate of coronary heart disease.
Paraoxonase polymorphism (Gln192-Arg) is associated with coronary heart disease in Japanese noninsulin-dependent diabetes mellitus.
Paraoxonase polymorphisms and coronary heart disease.
Paraoxonase PON1 polymorphism leu-Met54 is associated with carotid atherosclerosis: results of the Austrian Stroke Prevention Study.
Paraoxonase promoter polymorphism T(-107)C and relative paraoxonase deficiency as determinants of risk of coronary artery disease.
Paraoxonase status in coronary heart disease: are activity and concentration more important than genotype?
Paraoxonase-1 (PON1) promoter region polymorphisms, serum PON1 status and coronary heart disease.
Paraoxonase-1 L55M polymorphism is associated with an abnormal oral glucose tolerance test and differentiates high risk coronary disease families.
Paraoxonase-1 promoter polymorphism C--107T and serum apolipoprotein AI interact to modulate serum paraoxonase-1 status.
Paraoxonase: biochemistry, genetics and relationship to plasma lipoproteins.
Polymorphisms of pon1 and pon2 genes in hemodialyzed patients.
PON2 and PPARG polymorphisms as biomarkers of risk for coronary heart disease.
Positive Clinical Response to Clopidogrel is Independent of Paraoxonase 1 Q192R and CYP2C19 Genetic Variants.
Promoter polymorphism T(-107)C of the paraoxonase PON1 gene is a risk factor for coronary heart disease in type 2 diabetic patients.
Quantitative Assessment of the Influence of Paraoxonase 1 Activity and Coronary Heart Disease Risk.
Risk of myocardial infarction associated with Gln/Arg 192 polymorphism in the human paraoxonase gene and diabetes mellitus. The REGICOR Investigators.
Role of angiotensin converting enzyme, paraoxonase 1 55, 192 gene polymorphisms in syndrome X and coronary heart disease.
Serum apolipoprotein j in health, coronary heart disease and type 2 diabetes mellitus.
Serum paraoxonase activity and phenotype distribution in Turkish subjects with coronary heart disease and its relationship to serum lipids and lipoproteins.
Significant association between paraoxonase 1 rs662 polymorphism and coronary heart disease : A meta-analysis in the Chinese population.
Smoking is associated with reduced serum paraoxonase activity and concentration in patients with coronary artery disease.
The codon 55 polymorphism in the paraoxonase 1 gene is not associated with the risk of coronary heart disease in Asian Indians and Chinese.
The correlation of homocysteine-thiolactonase activity of the paraoxonase (PON1) protein with coronary heart disease status.
The effect of micronised fenofibrate on paraoxonase activity in patients with coronary heart disease.
The Gln/Arg polymorphism of human paraoxonase (PON 192) is not related to myocardial infarction in the ECTIM Study.
The impact of cytochrome 450 and Paraoxonase polymorphisms on clopidogrel resistance and major adverse cardiac events in coronary heart disease patients after percutaneous coronary intervention.
The paraoxonase gene family and coronary heart disease.
The paraoxonase Leu-Met54 and Gln-Arg191 gene polymorphisms are not associated with the risk of coronary heart disease.
The relationships between PON1 activity as well as oxLDL levels and coronary artery lesions in CHD patients with diabetes mellitus or impaired fasting glucose.
Unexpectedly higher diazoxon hydrolysis by serum paraoxonase-1 in coronary heart disease.
[Age related decrease of high density lipoproteins (HDL) in women after menopause. Quantification of HDL with genetically determined HDL arylesterase in women with healthy coronary vessels and in women with angiographically verified coronary heart disease]
[Association of paraoxonase polymorphisms and serum homocysteine thiolactone complex with coronary heart disease]
[Low paraoxonase and arylesterase plasma activities in Mexican patients with coronary artery disease]
[Paraoxonase, something more than an enzyme?]
[Relationships between PON1 L55M polymorphism and coronary heart diseases complicated with fasting hyperglycemia in Han populations in Guangdong]
[Study of the association between paraoxonase1 55 Met/Leu, paraoxonase2 148 Ala/Gly and manganese superoxide dismutase (MnSOD) 9 Ala/Val genetic polymorphisms and coronary heart disease]
[The paraoxonase Gln-Arg192 polymorphism in patients with coronary heart disease in Chinese population]
Coronary Stenosis
Matrix metalloproteinase-9 and paraoxonase 1 Q/R192 gene polymorphisms and the risk of coronary artery stenosis in Iranian subjects.
Paraoxonase gene polymorphism in Japanese subjects with coronary heart disease.
COVID-19
Altered high-density lipoprotein composition and functions during severe COVID-19.
Crohn Disease
Correlation of Paraoxonase-1 with the Severity of Crohn's Disease.
P074. Circulating adipokynes and Paraoxonase-1 activity in overweight Crohn's disease patients.
Paraoxonase (PON)1 192R allele carriage is associated with reduced risk of inflammatory bowel disease.
Paraoxonase-1 status in Crohn's disease and ulcerative colitis.
Cushing Syndrome
CONDITIONING FACTORS FOR HIGH CARDIOVASCULAR RISK IN PATIENTS WITH CUSHING SYNDROME.
cystathionine beta-synthase deficiency
Lipid, Oxidative and Inflammatory Profile and Alterations in the Enzymes Paraoxonase and Butyrylcholinesterase in Plasma of Patients with Homocystinuria Due CBS Deficiency: The Vitamin B12 and Folic Acid Importance.
Paraoxonase-1 expression is up-regulated in Down syndrome fetal liver.
Cystic Fibrosis
An improved method for phenotyping individuals for the human serum paraoxonase arylesterase polymorphism.
Characteristics of the genetically determined allozymic forms of human serum paraoxonase/arylesterase.
Expression of PPAR? and Paraoxonase 2 Correlated with Pseudomonas aeruginosa Infection in Cystic Fibrosis.
Identification and analysis of the salt tolerant property of AHL lactonase (AiiATSAWB ) of Bacillus species.
Linkage between the loci for cystic fibrosis and paraoxonase.
Linkage relationships of paraoxonase (PON) with other markers: indication of PON-cystic fibrosis synteny.
Molecular basis for the polymorphic forms of human serum paraoxonase/arylesterase: glutamine or arginine at position 191, for the respective A or B allozymes.
Plasminogen activator inhibitor type 1 gene is located at region q21.3-q22 of chromosome 7 and genetically linked with cystic fibrosis.
The Sweat Metabolome of Screen-Positive Cystic Fibrosis Infants: Revealing Mechanisms beyond Impaired Chloride Transport.
Cystitis
Evaluation of oxidative stress status and antioxidant capacity in patients with painful bladder syndrome/interstitial cystitis: preliminary results of a randomised study.
Cysts
Esterase activity in the guinea pig thyroid under normal and pathological conditions (vitamin A deficiency) with special regard to cyst-like structures.
Dementia
Association of adiponectin, leptin and resistin with inflammatory markers and obesity in dementia.
Catalytic properties and distribution profiles of paraoxonase and cholinesterase phenotypes in human sera.
Codon 311 (Cys --> Ser) polymorphism of paraoxonase-2 gene is associated with apolipoprotein E4 allele in both Alzheimer's and vascular dementias.
Genetic polymorphisms in older subjects with vascular or Alzheimer's dementia.
Paraoxonase 1 (PON1) gene -108C>T and p.Q192R polymorphisms and arylesterase activity of the enzyme in patients with dementia.
Paraoxonase 1 decline and lipid peroxidation rise reflect a degree of brain atrophy and vascular impairment in dementia.
Paraoxonase 1 gene polymorphisms and dementia in humans.
Paraoxonase activity and dementia.
PON-1 and ferroxidase activities in older patients with mild cognitive impairment, late onset Alzheimer's disease or vascular dementia.
Positive correlation of paraoxonase 1 (PON1) activity with serum insulin level and HOMA-IR in dementia. A possible advantageous role of PON1 in dementia development.
Profile of the Paraoxonase 1 (PON1) Gene 192Q/R Polymorphism and Clinical Associations among Older Singaporean Chinese with Alzheimer's and Mixed Dementia.
Serum paraoxonase and arylesterase activities of paraoxonase-1 (PON-1), mild cognitive impairment, and 2-year conversion to dementia: A pilot study.
The relationship between serum paraoxonase levels and carotid atherosclerotic plaque formation in Alzheimer's patients.
[The early diagnosis and differential diagnosis of Alzheimer's disease with clinical methods]
Dementia, Vascular
Arylesterase Activity of Paraoxonase-1 in Serum and Cerebrospinal Fluid of Patients with Alzheimer's Disease and Vascular Dementia.
Assessment of Paraoxonase 1 Activity in Patients With Alzheimer's Disease and Vascular Dementia.
Association of adiponectin, leptin and resistin with inflammatory markers and obesity in dementia.
Codon 311 (Cys --> Ser) polymorphism of paraoxonase-2 gene is associated with apolipoprotein E4 allele in both Alzheimer's and vascular dementias.
Decreased arylesterase activity of paraoxonase-1 (PON-1) might be a common denominator of neuroinflammatory and neurodegenerative diseases.
Genetic polymorphisms in older subjects with vascular or Alzheimer's dementia.
Paraoxonase 1 decline and lipid peroxidation rise reflect a degree of brain atrophy and vascular impairment in dementia.
Serum paraoxonase activity changes in patients with Alzheimer's disease and vascular dementia.
Serum paraoxonase and arylesterase activities of paraoxonase-1 (PON-1), mild cognitive impairment, and 2-year conversion to dementia: A pilot study.
Synergistic Epistasis of Paraoxonase 1 (rs662 and rs85460) and Apolipoprotein E4 Genes in Pathogenesis of Alzheimer's Disease and Vascular Dementia.
Diabetes Complications
Association between PON 1 polymorphisms, PON activity and diabetes complications.
Evaluation of paraoxonase 1 arylesterase activity and lipid peroxide levels in patients with type 1 diabetes.
Paraoxonase 1 polymorphisms (L55M and Q192R) as a genetic marker of diabetic nephropathy in youth with type 1 diabetes.
PON1 55 and 192 Gene Polymorphisms in Type 2 Diabetes Mellitus Patients in a Turkish Population.
Diabetes Mellitus
Antioxidant potential, paraoxonase 1, ceruloplasmin activity and C-reactive protein concentration in diabetic retinopathy.
Association between M/L55-polymorphism of paraoxonase enzyme and oxidative DNA damage in patients with type 2 diabetes mellitus and in control subjects.
Association between paraoxonase 1 activity and severity of coronary artery disease in patients with acute coronary syndromes.
Association of cholesteryl ester transfer protein genotypes with paraoxonase-1 activity, lipid profile and oxidative stress in type 2 diabetes mellitus: A study in San Luis, Argentina.
Association of elevated apoA-I glycation and reduced HDL-associated paraoxonase1, 3 activity, and their interaction with angiographic severity of coronary artery disease in patients with type 2 diabetes mellitus.
Association of PON2 Gene Polymorphisms (Ser311Cys and Ala148Gly) With the Risk of Developing Type 2 Diabetes Mellitus in the Chinese Population.
Association of RAGE gene polymorphism with circulating AGEs level and paraoxonase activity in relation to macro-vascular complications in Indian type 2 diabetes mellitus patients.
Association of the novel cardiovascular risk factors paraoxonase 1 and cystatin C in type 2 diabetes.
Carotid artery intima media thickness associates with skin autofluoresence in non-diabetic subjects without clinically manifest cardiovascular disease.
Catalase and paraoxonase in hypertensive type 2 diabetes mellitus: correlation with glycemic control.
Correlation between the activities of lipoprotein lipase and paraoxonase in type 2 diabetes mellitus.
Cross-sectional correlates of paraoxonase 1 and soluble intercellular adhesion molecule-1 in metabolic syndrome patients with and without diabetes.
Decrease of serum paraoxonase activity in chronic renal failure.
Effect of Eicosapentaenoic Acid Supplementation on Paraoxonase 2 Gene Expression in Patients with Type 2 Diabetes Mellitus: a Randomized Double-blind Clinical Trial.
Effect of insulin resistance on serum paraoxonase activity in a nondiabetic population.
Effect of Lipoic Acid on Serum Paraoxonase-1 and Paraoxonase-3 Protein Levels and Activities in Diabetic Rats.
Effects of n-3 Polyunsaturated Fatty Acids (PUFAs) on Circulating Adiponectin and Leptin in Subjects with Type 2 Diabetes Mellitus.
Effects of rosiglitazone on serum paraoxonase activity and metabolic parameters in patients with type 2 diabetes mellitus.
Effects of vitamin A, C and E, or omega-3 fatty acid supplementation on the level of paraoxonase and arylesterase activity in streptozotocin-induced diabetic rats: an investigation of activities in plasma, and heart and liver homogenates.
Ethnic variations in paraoxonase1 polymorphism in the Malaysian population.
European versus Asian differences for the associations between paraoxonase-1 genetic polymorphisms and susceptibility to type 2 diabetes mellitus.
Evaluation of Relationship Between Arylesterase-Based Activity and Genetic Variants of Paraoxonase1 in T2DM Patients within Golestan Province.
Gender differences in the association of gene polymorphisms with type 2 diabetes mellitus.
Genetic risk for restenosis after coronary balloon angioplasty.
Gln-Arg192 polymorphism of paraoxonase 1 is associated with carotid intima-media thickness in patients of type 2 diabetes mellitus of Chinese.
Glycation impairs high-density lipoprotein function.
HDL oxidability and its protective effect against LDL oxidation in Type 2 diabetic patients.
Investigation of the relationship between atherosclerosis and paraoxonase or homocysteine thiolactonase activity in patients with type 2 diabetes mellitus using a commercially available assay.
Lack of association between carotid intima-media thickness and paraoxonase gene polymorphism in non-insulin dependent diabetes mellitus.
Low paraoxonase activity in type II diabetes mellitus complicated by retinopathy.
Modulation by blood glucose levels of activity and concentration of paraoxonase in young patients with type 1 diabetes mellitus.
Paraoxonase (PON)-1: a brief overview on genetics, structure, polymorphisms and clinical relevance.
Paraoxonase (PON1) 55 and 192 polymorphism and its effects to oxidant-antioxidant system in turkish patients with type 2 diabetes mellitus.
Paraoxonase (PON1) activity in north west Indian Punjabis with coronary artery disease & type 2 diabetes mellitus.
Paraoxonase 1 activities and its gene promoter single nucleotide polymorphisms (-108, -126, and -162) in diabetes mellitus.
Paraoxonase 1 activity as a predictor of cardiovascular disease in type 2 diabetes.
Paraoxonase 1 Activity, Polymorphism and Atherosclerosis Risk Factors in Patients Undergoing Coronary Artery Surgery.
Paraoxonase 1 gene (Q192R) polymorphism confers susceptibility to coronary artery disease in type 2 diabetes patients: Evidence from case-control studies.
Paraoxonase 1 gene polymorphisms and enzyme activities in diabetes mellitus.
Paraoxonase 1 Gln/Arg polymorphism is associated with the risk of microangiopathy in Type 2 diabetes mellitus.
Paraoxonase 1: a better atherosclerotic risk predictor than HDL in type 2 diabetes mellitus.
Paraoxonase 55 and 192 polymorphism and its relationship to serum paraoxonase activity and serum lipids in Turkish patients with non-insulin dependent diabetes mellitus.
Paraoxonase and arylesterase activities in the serum of two hyperlipoproteinaemic patients after repeated extracorporal lipid precipitation.
Paraoxonase lactonase activity, inflammation and antioxidant status in plasma of patients with type 1 diabetes mellitus.
Paraoxonase, oxidized low density lipoprotein, monocyte chemoattractant protein-1 and adhesion molecules are associated with macrovascular complications in patients with type 2 diabetes mellitus.
Paraoxonase-1 activities in children and adolescents with type 1 diabetes mellitus.
Paraoxonase-1 activity is positively related to phospholipid transfer protein activity in type 2 diabetes mellitus: Role of large HDL particles.
Paraoxonase-1 gene Q192R and L55M polymorphisms and risk of cardiovascular disease in Egyptian patients with type 2 diabetes mellitus.
Paraoxonase/arylesterase in serum of patients with type II diabetes mellitus.
Pharmacological interactions of paraoxonase 1 (PON1): A HDL-bound antiatherogenic enzyme.
Potential Association of Paraoxonase 1, Type 2 Diabetes Mellitus and Periodontitis.
Prevalence of paraoxonase-1 polymorphisms in diabetes mellitus type 2 Greek patients.
Relations of lysophosphatidylcholine in low-density lipoprotein with serum lipoprotein-associated phospholipase A2, paraoxonase and homocysteine thiolactonase activities in patients with type 2 diabetes mellitus.
Risk of myocardial infarction associated with Gln/Arg 192 polymorphism in the human paraoxonase gene and diabetes mellitus. The REGICOR Investigators.
Serum paraoxonase (PON1) 55 and 192 polymorphism and paraoxonase activity and concentration in non-insulin dependent diabetes mellitus.
Serum paraoxonase activity and paraoxonase gene polymorphism in type 2 diabetic patients with or without vascular complications.
Serum paraoxonase activity, concentration, and phenotype distribution in diabetes mellitus and its relationship to serum lipids and lipoproteins.
Serum paraoxonase-1 (PON1) activities (PONase/AREase) and polymorphisms in patients with type 2 diabetes mellitus in a North-West Indian population.
Serum paraoxonase-1 activity is more closely related to HDL particle concentration and large HDL particles than to HDL cholesterol in Type 2 diabetic and non-diabetic subjects.
Study on paraoxonase 1 in type 2 diabetes mellitus.
The association between paraoxonase 1 activity and the susceptibilities of diabetes mellitus, diabetic macroangiopathy and diabetic microangiopathy.
The Effect of Eicosapentaenoic Acid on the Serum Levels and Enzymatic Activity of Paraoxonase 1 in the Patients With Type 2 Diabetes Mellitus.
The most effective polymorphisms of paraoxonase-1 gene on enzyme activity and concentration of paraoxonase-1 protein in type 2 diabetes mellitus patients and non-diabetic individuals: A systematic review and meta-analysis.
The relationship of oral disturbances of diabetes mellitus patients with paraoxonase gene polymorphisms.
Vitamin E Improves Serum Paraoxonase-1 Activity and Some Metabolic Factors in Patients with Type 2 Diabetes: No Effects on Nitrite/Nitrate Levels.
[A search for association between the polymorphic markers of PON1 and PON2 genes and diabetic nephropathy in patients with type I diabetes mellitus]
[Genetic polymorphism of pyruvate dehydrogenase kinase 4 (PDK4), paraoxonase 2 (PON2), and fatty acid binding protein 2 (FABP2) in the NIDDM population of Senegal]
[Relationships between PON1 L55M polymorphism and coronary heart diseases complicated with fasting hyperglycemia in Han populations in Guangdong]
[Study of SOD and PON-1 expression in type 2 diabetes mellitus nephropathy and its clinical significance].
[The association of paraoxonase 2 gene C311S variant with ischemic stroke in Chinese type 2 diabetes mellitus patients]
[The effects of paraoxonase-1 and oxidized low density lipoprotein on nephropathy in type-2 diabetes mellitus]
Diabetes Mellitus, Type 1
A variant of paraoxonase (PON1) gene is associated with diabetic retinopathy in IDDM.
Association between p.Leu54Met polymorphism at the paraoxonase-1 gene and plantar fascia thickness in young subjects with type 1 diabetes.
Association between PON 1 polymorphisms, PON activity and diabetes complications.
Can paraoxonase 1 polymorphisms (L55 M and Q192 R) protect children with type 1 diabetes against lipid abnormalities?
Evaluation of paraoxonase 1 arylesterase activity and lipid peroxide levels in patients with type 1 diabetes.
High Concentration of Medium-Sized HDL Particles and Enrichment in HDL Paraoxonase 1 Associate With Protection From Vascular Complications in People With Long-standing Type 1 Diabetes.
Modulation by blood glucose levels of activity and concentration of paraoxonase in young patients with type 1 diabetes mellitus.
Paraoxonase 1 polymorphisms (L55M and Q192R) as a genetic marker of diabetic nephropathy in youth with type 1 diabetes.
Paraoxonase gene cluster is a genetic marker for early microvascular complications in type 1 diabetes.
Paraoxonase lactonase activity, inflammation and antioxidant status in plasma of patients with type 1 diabetes mellitus.
Paraoxonase-1 activities in children and adolescents with type 1 diabetes mellitus.
Serum paraoxonase activity in patients with type 1 diabetes compared to healthy controls.
Serum paraoxonase activity, concentration, and phenotype distribution in diabetes mellitus and its relationship to serum lipids and lipoproteins.
[A search for association between the polymorphic markers of PON1 and PON2 genes and diabetic nephropathy in patients with type I diabetes mellitus]
Diabetes Mellitus, Type 2
Abnormalities in the relationship of paraoxonase 1 with HDL and apolipoprotein A1 and their possible connection to HDL dysfunctionality in type 2 diabetes.
Arylesterase activity but not PCSK9 levels is associated with chronic kidney disease in type 2 diabetes.
Association between Genetic Variants and Diabetes Mellitus in Iranian Populations: A Systematic Review of Observational Studies.
Association between M/L55-polymorphism of paraoxonase enzyme and oxidative DNA damage in patients with type 2 diabetes mellitus and in control subjects.
Association between promoter polymorphism (-108C>T) of paraoxonase1 gene and it(')s paraoxonase activity in patients with Type2 diabetes in northern Iran.
Association of elevated apoA-I glycation and reduced HDL-associated paraoxonase1, 3 activity, and their interaction with angiographic severity of coronary artery disease in patients with type 2 diabetes mellitus.
Association of PON2 Gene Polymorphisms (Ser311Cys and Ala148Gly) With the Risk of Developing Type 2 Diabetes Mellitus in the Chinese Population.
Association of RAGE gene polymorphism with circulating AGEs level and paraoxonase activity in relation to macro-vascular complications in Indian type 2 diabetes mellitus patients.
Association of Serum Paraoxonase 1 Activities, Polymorphisms and Oxidative Stress in Breast Cancer Patients with Type 2 Diabetes Mellitus.
Association of the novel cardiovascular risk factors paraoxonase 1 and cystatin C in type 2 diabetes.
Catalase and paraoxonase in hypertensive type 2 diabetes mellitus: correlation with glycemic control.
Correlation between the activities of lipoprotein lipase and paraoxonase in type 2 diabetes mellitus.
Cross-sectional correlates of paraoxonase 1 and soluble intercellular adhesion molecule-1 in metabolic syndrome patients with and without diabetes.
Decreased paraoxonase 2 enzymatic activity in monocyte/macrophages cells. A comparative in vivo and in vitro study for diabetes.
Distribution of Paraoxonase-1 (PON-1) and Lipoprotein Phospholipase A2 (Lp-PLA2) across Lipoprotein Subclasses in Subjects with Type 2 Diabetes.
Effect of Eicosapentaenoic Acid Supplementation on Paraoxonase 2 Gene Expression in Patients with Type 2 Diabetes Mellitus: a Randomized Double-blind Clinical Trial.
Effect of insulin resistance on serum paraoxonase activity in a nondiabetic population.
Effect of pomegranate juice on paraoxonase enzyme activity in patients with type 2 diabetes.
Effects of n-3 Polyunsaturated Fatty Acids (PUFAs) on Circulating Adiponectin and Leptin in Subjects with Type 2 Diabetes Mellitus.
Effects of rosiglitazone on serum paraoxonase activity and metabolic parameters in patients with type 2 diabetes mellitus.
European versus Asian differences for the associations between paraoxonase-1 genetic polymorphisms and susceptibility to type 2 diabetes mellitus.
Gender differences in the association of gene polymorphisms with type 2 diabetes mellitus.
Genotype and phenotype of salt-stimulated paraoxonase 1 (PON1) is associated with atherogenic indices in type 2 diabetes.
Gln-Arg192 polymorphism of paraoxonase 1 is associated with carotid intima-media thickness in patients of type 2 diabetes mellitus of Chinese.
Gln-Arg192 polymorphism of paraoxonase and coronary heart disease in type 2 diabetes.
HDL oxidability and its protective effect against LDL oxidation in Type 2 diabetic patients.
Hormone-replacement therapy increases serum paraoxonase arylesterase activity in diabetic postmenopausal women.
Importance of paraoxonase 1 (PON1) as an antioxidant and antiatherogenic enzyme in the cardiovascular complications of type 2 diabetes: Genotypic and phenotypic evaluation.
Incident type 2 diabetes is associated with HDL, but not with its anti-oxidant constituent - paraoxonase-1: The prospective cohort PREVEND study.
Investigation of the relationship between atherosclerosis and paraoxonase or homocysteine thiolactonase activity in patients with type 2 diabetes mellitus using a commercially available assay.
Leisure time physical activity is associated with improved HDL functionality in high cardiovascular risk individuals: a cohort study.
Low human paraoxonase predicts cardiovascular events in Japanese patients with type 2 diabetes.
Lower Serum Paraoxonase-1 Activity Is Related to Linoleic and Docosahexanoic Fatty Acids in Patients with Type 2 Diabetes.
Myeloperoxidase and paraoxonase-1 in type 2 diabetic patients.
Paraoxonase (PON1) 55 and 192 polymorphism and its effects to oxidant-antioxidant system in turkish patients with type 2 diabetes mellitus.
Paraoxonase (PON1) activity in north west Indian Punjabis with coronary artery disease & type 2 diabetes mellitus.
Paraoxonase 1 (PON1)-L55M among common variants in the coding region of the paraoxonase gene family may contribute to the glycemic control in type 2 diabetes.
Paraoxonase 1 192 Gln/Arg gene polymorphism and cerebrovascular disease: interaction with type 2 diabetes.
Paraoxonase 1 activity as a predictor of cardiovascular disease in type 2 diabetes.
Paraoxonase 1 Activity in Chylomicrons and VLDL: The Effect of Type 2 Diabetes and Meals Rich in Saturated Fat and Oleic Acid.
Paraoxonase 1 gene (Q192R) polymorphism confers susceptibility to coronary artery disease in type 2 diabetes patients: Evidence from case-control studies.
Paraoxonase 1 gene polymorphisms concerning non-insulin-dependent diabetes mellitus nephropathy in hemodialysis patients.
Paraoxonase 1 Gln/Arg polymorphism is associated with the risk of microangiopathy in Type 2 diabetes mellitus.
Paraoxonase 1 phenotype distribution and activity differs in subjects with newly diagnosed Type 2 diabetes (the CODAM Study).
Paraoxonase 192 Gln/Arg gene polymorphism, coronary artery disease, and myocardial infarction in type 2 diabetes.
Paraoxonase 1: a better atherosclerotic risk predictor than HDL in type 2 diabetes mellitus.
Paraoxonase 2 (PON2) polymorphisms and development of renal dysfunction in type 2 diabetes: UKPDS 76.
Paraoxonase 55 and 192 polymorphism and its relationship to serum paraoxonase activity and serum lipids in Turkish patients with non-insulin dependent diabetes mellitus.
Paraoxonase polymorphism (Gln192-Arg) is associated with coronary heart disease in Japanese noninsulin-dependent diabetes mellitus.
Paraoxonase, oxidized low density lipoprotein, monocyte chemoattractant protein-1 and adhesion molecules are associated with macrovascular complications in patients with type 2 diabetes mellitus.
Paraoxonase-1 activity is positively related to phospholipid transfer protein activity in type 2 diabetes mellitus: Role of large HDL particles.
Paraoxonase-1 gene Q192R and L55M polymorphisms and risk of cardiovascular disease in Egyptian patients with type 2 diabetes mellitus.
Paraoxonase-1 is not associated with coronary artery calcification in type 2 diabetes: Results from the PREDICT study.
Paraoxonase: another factor in NIDDM cardiovascular disease.
Plasma markers of endothelial dysfunction in type 2 diabetics.
Potential Association of Paraoxonase 1, Type 2 Diabetes Mellitus and Periodontitis.
Reduction of paraoxonase-1 activity may contribute the qualitative impairment of HDL particles in patients with type 2 diabetes.
Relations of lysophosphatidylcholine in low-density lipoprotein with serum lipoprotein-associated phospholipase A2, paraoxonase and homocysteine thiolactonase activities in patients with type 2 diabetes mellitus.
Relationship of High-Density Lipoprotein-Associated Arylesterase Activity to Systolic Heart Failure in Patients with and without Type 2 Diabetes.
Serum arylesterase/diazoxonase activity and genetic polymorphisms in patients with type 2 diabetes.
Serum paraoxonase activity and paraoxonase gene polymorphism in type 2 diabetic patients with or without vascular complications.
Serum paraoxonase activity, concentration, and phenotype distribution in diabetes mellitus and its relationship to serum lipids and lipoproteins.
Serum paraoxonase-1 (PON1) activities (PONase/AREase) and polymorphisms in patients with type 2 diabetes mellitus in a North-West Indian population.
Serum paraoxonase-1 activity is more closely related to HDL particle concentration and large HDL particles than to HDL cholesterol in Type 2 diabetic and non-diabetic subjects.
Sex Difference Impacts on the Relationship between Paraoxonase-1 (PON1) and Type 2 Diabetes.
Study on paraoxonase 1 in type 2 diabetes mellitus.
The anti-inflammatory function of HDL is impaired in type 2 diabetes: role of hyperglycemia, paraoxonase-1 and low grade inflammation.
The common variant Q192R at the paraoxonase 1 (PON1) gene and its activity are responsible for a portion of the altered antioxidant status in type 2 diabetes.
The Effect of Eicosapentaenoic Acid on the Serum Levels and Enzymatic Activity of Paraoxonase 1 in the Patients With Type 2 Diabetes Mellitus.
The effect of meals rich in thermally stressed olive and safflower oils on postprandial serum paraoxonase activity in patients with diabetes.
The effect of resveratrol supplementation on serum levels of asymmetric de-methyl-arginine and paraoxonase 1 activity in patients with type 2 diabetes: A randomized, double-blind controlled trial.
The gene-treatment interaction of paraoxonase-1 gene polymorphism and statin therapy on insulin secretion in Japanese patients with type 2 diabetes: Fukuoka diabetes registry.
The Met54Leu polymorphism of paraoxonase (PON) enzyme gene is not a genetic risk factor for non-insulin-dependent diabetes mellitus in Finns.
The most effective polymorphisms of paraoxonase-1 gene on enzyme activity and concentration of paraoxonase-1 protein in type 2 diabetes mellitus patients and non-diabetic individuals: A systematic review and meta-analysis.
The Q192R polymorphism of the paraoxonase-1 (PON1) gene is associated with susceptibility to gestational diabetes mellitus in the Greek population.
The Ser311Cys variation in the paraoxonase 2 gene increases the risk of type 2 diabetes in northern Chinese.
Vitamin E Improves Serum Paraoxonase-1 Activity and Some Metabolic Factors in Patients with Type 2 Diabetes: No Effects on Nitrite/Nitrate Levels.
[Genetic polymorphism of pyruvate dehydrogenase kinase 4 (PDK4), paraoxonase 2 (PON2), and fatty acid binding protein 2 (FABP2) in the NIDDM population of Senegal]
[Relationships between PON1 L55M polymorphism and coronary heart diseases complicated with fasting hyperglycemia in Han populations in Guangdong]
[Study of SOD and PON-1 expression in type 2 diabetes mellitus nephropathy and its clinical significance].
[The association of paraoxonase 2 gene C311S variant with ischemic stroke in Chinese type 2 diabetes mellitus patients]
Diabetes, Gestational
Decreased paraoxonase and arylesterase activities in the pathogenesis of future atherosclerotic heart disease in women with gestational diabetes mellitus.
Evaluation of the future atherosclerotic heart disease with oxidative stress and carotid artery intima media thickness in gestational diabetes mellitus.
Lactonase activity and status of paraoxonase 1 and oxidative stress in neonates of women with gestational diabetes mellitus.
Lactonase Activity, Status, and Genetic Variations of Paraoxonase 1 in Women with Gestational Diabetes Mellitus.
Protein oxidation markers in women with and without gestational diabetes mellitus: a possible relation with paraoxonase activity.
Relationship between the paraoxonase 1 gene glutamine 192 to arginine polymorphism and gestational diabetes mellitus in Saudi women.
The Q192R polymorphism of the paraoxonase-1 (PON1) gene is associated with susceptibility to gestational diabetes mellitus in the Greek population.
Diabetic Angiopathies
The association between paraoxonase 1 activity and the susceptibilities of diabetes mellitus, diabetic macroangiopathy and diabetic microangiopathy.
The Associations between Paraoxonase 1 L55M/Q192R Genetic Polymorphisms and the Susceptibilities of Diabetic Macroangiopathy and Diabetic Microangiopathy: A Meta-Analysis.
Diabetic Foot
Diet and paraoxonase 1 enzymatic activity in diabetic foot patients from romania and belgium: favorable association of high flavonoid dietary intake with arylesterase activity.
Investigation of ischemia-modified albumin levels and some atherosclerosis-related serum parameters in patients with diabetic foot.
Diabetic Nephropathies
Association of paraoxonase gene polymorphisms with diabetic nephropathy and retinopathy.
Comment--to: Pinizzotto M, Castillo E, Fiaux M, Temler E, Gaillard RC, Ruiz J (2001) Paraoxonase 2 polymorphisms are associated with diabetic nephropathy in Type II diabetes. Diabetologia 44: 104-107.
Evaluation of Paraoxonase, Arylesterase, and Homocysteine Thiolactonase Activities in Patients with Diabetes and Incipient Diabetes Nephropathy.
Lovastatin enhances paraoxonase enzyme activity and quells low-density lipoprotein susceptibility to oxidation in type 2 diabetic nephropathy.
Paraoxonase 1 polymorphisms (L55M and Q192R) as a genetic marker of diabetic nephropathy in youth with type 1 diabetes.
Paraoxonase2 polymorphisms are associated with nephropathy in Type II diabetes.
Polymorphisms of human paraoxonase 1 gene (PON1) and susceptibility to diabetic nephropathy in type I diabetes mellitus.
Protective effect of paraoxonase 1 of high-density lipoprotein in type 2 diabetic patients with nephropathy.
Relations of lysophosphatidylcholine in low-density lipoprotein with serum lipoprotein-associated phospholipase A2, paraoxonase and homocysteine thiolactonase activities in patients with type 2 diabetes mellitus.
[A search for association between the polymorphic markers of PON1 and PON2 genes and diabetic nephropathy in patients with type I diabetes mellitus]
[The effects of paraoxonase-1 and oxidized low density lipoprotein on nephropathy in type-2 diabetes mellitus]
Diabetic Retinopathy
A variant of paraoxonase (PON1) gene is associated with diabetic retinopathy in IDDM.
Antioxidant potential, paraoxonase 1, ceruloplasmin activity and C-reactive protein concentration in diabetic retinopathy.
Association of paraoxonase gene polymorphisms with diabetic nephropathy and retinopathy.
Homocysteinethiolactone and paraoxonase: novel markers of diabetic retinopathy.
Disorders of Excessive Somnolence
Sleepiness, inflammation and oxidative stress markers in middle-aged males with obstructive sleep apnea without metabolic syndrome: a cross-sectional study.
Down Syndrome
Paraoxonase-1 expression is up-regulated in Down syndrome fetal liver.
Drug Resistant Epilepsy
An evaluation of serum paraoxonase together with arylesterase activities and oxidative stress in children with intractable epilepsy: a cross-sectional study.
Dyslipidemias
Accelerated atherosclerosis in rheumatoid arthritis.
Association of lipid profile with serum PON1 concentration in patients with chronic kidney disease.
Association of midgestation paraoxonase 1 activity and pregnancies complicated by preterm birth.
Curcumin combined with metformin decreases glycemia and dyslipidemia, and increases paraoxonase activity in diabetic rats.
Effect of yerba mate and green tea on paraoxonase and leptin levels in patients affected by overweight or obesity and dyslipidemia: a randomized clinical trial.
Hypertension in children (12-14 years)--a case-control study in Bursa, Turkey.
Increased low-density lipoprotein oxidation and impaired high-density lipoprotein antioxidant defense are associated with increased macrophage homing and atherosclerosis in dyslipidemic obese mice: LCAT gene transfer decreases atherosclerosis.
Molecular characterization and expression analysis of the porcine paraoxonase 3 (PON3) gene.
Paraoxonase enzyme activity and dyslipidemia in chronic kidney disease patients.
Q192R Polymorphism of Paraoxonase 1 Gene Associated with Insulin Resistance in Mexican Children.
Serum lipid profile paraoxonase and arylesterase activities in psoriasis.
The effects of lipid-lowering therapy on paraoxonase activities and their relationships with the oxidant-antioxidant system in patients with dyslipidemia.
[Fish by-products oil corrects dyslipidemia, improves reverse cholesterol transport and stimulates paraoxonase-1 activity in obese rat].
Echinococcosis
Oxidant/Antioxidant Status, PON1 and ARES Activities, Trace Element Levels, and Histological Alterations in Sheep with Cystic Echinococcosis.
Endometrial Neoplasms
Assessment of serum paraoxonase and arylesterase activity in patients with endometrial cancer.
Serum paraoxonase 1 activity and protein N-homocysteinylation in primary human endometrial cancer.
Endometriosis
Association between Serum Paraoxonase 1 Activities (PONase/AREase) and L55M Polymorphism in Risk of Female Infertility.
Atherosclerotic cardiovascular disease in women with endometriosis: a systematic review of risk factors and prospects for early surveillance.
Serum paraoxonase-1 activity in women with endometriosis and its relationship with the stage of the disease.
Serum tumor necrosis factor-?, interleukin-6, monocyte chemotactic protein-1 and paraoxonase-1 profiles in women with endometriosis, PCOS, or unexplained infertility.
There is no relationship between Paraoxonase serum level activity in women with endometriosis and the stage of the disease: an observational study.
Endotoxemia
Serial measurements of Paraoxonase-1 (PON-1) activity in horses with experimentally induced endotoxemia.
Serum butyrylcholinesterase and paraoxonase 1 in a canine model of endotoxemia: Effects of choline administration.
Enteritis
Inflammatory and oxidative biomarkers of disease severity in dogs with parvoviral enteritis.
Epilepsy
Changes in the anti-oxidant system in adult epilepsy patients receiving anti-epileptic drugs.
Erectile Dysfunction
Assessment of the acute effects of tadalafil on the cardiovascular system based on examination of serum oxidative status and paraoxonase activity in men with erectile dysfunction: a preliminary study.
Paraoxonase activity in patients with erectile dysfunction.
Esophageal Neoplasms
Paraoxonase 3 is involved in the multi-drug resistance of esophageal cancer.
Esophageal Squamous Cell Carcinoma
Assessment of PPARGC1A, PPARGC1B, and PON1 Genetic Polymorphisms in Esophageal Squamous Cell Carcinoma Susceptibility in the Eastern Chinese Han Population: A Case-Control Study Involving 2351 Subjects.
Serum paraoxonase-1 enzyme activities and oxidative stress levels in patients with esophageal squamous cell carcinoma.
Essential Hypertension
Association of paraoxonase 1 (PON1) gene polymorphisms and concentration with essential hypertension.
Association of paraoxonase polymorphisms with carotid artery atherosclerosis in essential hypertension patients.
Q192R Paraoxonase (PON)1 Polymorphism, Insulin Sensitivity, and Endothelial Function in Essential Hypertensive Men.
Essential Tremor
Paraoxonase 1 (PON1) polymorphisms and risk for essential tremor.
Exfoliation Syndrome
Evaluation of oxidative stress and paraoxonase phenotypes in pseudoexfoliation syndrome and pseudoexfoliation glaucoma.
Paraoxonase 1 (PON1) promoter (-107T/C) and coding region (192Q/R and 55L/M) genetic variations in pseudoexfoliation syndrome and pseudoexfoliative glaucoma risk.
The Activities of Paraoxonase, Xanthine Oxidase, Adenosine Deaminase and the Level of Nitrite in Pseudoexfoliation Syndrome.
Total oxidative stress, paraoxonase and arylesterase levels at patients with pseudoexfoliation syndrome and pseudoexfoliative glaucoma.
Fabry Disease
Higher frequency of paraoxonase gene polymorphism and cardiovascular impairment among Brazilian Fabry Disease patients.
Paraoxonase (PON1) Gene Polymorphisms in Fabry Disease: Correlation with Renal Disease.
Familial Mediterranean Fever
Cu/Zn-superoxide dismutase, paraoxonase and arylesterase activities and malondialdehyde levels in patients with familial mediterranean fever.
Genetic polymorphisms of paraoxonase1 192 and glutathione peroxidase1 197 enzymes in familial Mediterranean fever.
Paraoxonase 1 and arylesterase levels in children with familial mediterranean fever.
Relationship of paraoxonase-1, malondialdehyde and mean platelet volume with markers of atherosclerosis in familial Mediterranean fever: an observational study.
Fatty Liver
A new marker for lipid peroxidation: Serum paraoxonase activity in non-alcoholic steatohepatitis.
A targeted multi-omics approach reveals paraoxonase-1 as a determinant of obesity-associated fatty liver disease.
Association of carotid intima media thickness with atherogenic index of plasma, apo B/apo A-I ratio and paraoxonase activity in patients with non-alcoholic fatty liver disease.
Chemokine ligand 2 and paraoxonase-1 in non-alcoholic fatty liver disease: The search for alternative causative factors.
Cytokines, paraoxonase-1, periostin and non-invasive liver fibrosis scores in patients with non-alcoholic fatty liver disease and persistently elevated aminotransferases: A pilot study.
Paraoxonase 1 and Non-Alcoholic Fatty Liver Disease: A Meta-Analysis.
Paraoxonase 1 and oxidative stress in paediatric non-alcoholic steatohepatitis.
Paraoxonase activity in sera of patients with non-alcoholic fatty liver disease.
Paraoxonase-1 activity, malondialdehyde and glutathione peroxidase in non-alcoholic fatty liver disease and the effect of atorvastatin.
Paraoxonase-1 Deficiency Is Associated with Severe Liver Steatosis in Mice Fed a High-fat High-cholesterol Diet: A Metabolomic Approach.
Paraoxonase-1 Serum Concentration and PON1 Gene Polymorphisms: Relationship with Non-Alcoholic Fatty Liver Disease.
Serum paraoxonase activity and oxidative stress and their relationship with obesity-related metabolic syndrome and non-alcoholic fatty liver disease in obese children and adolescents.
Serum Paraoxonase as an Indicator for Fatty Liver in Sheep.
Serum paraoxonase-1 as biomarker for improved diagnosis of fatty liver in dairy cows.
Feline Infectious Peritonitis
Role of paraoxonase-1 as a diagnostic marker for feline infectious peritonitis.
Serum biomarkers of oxidative stress in cats with feline infectious peritonitis.
Fibromyalgia
Paraoxonase and arylesterase activities in fibromyalgia.
Fibrosarcoma
Genome-wide association scan identifies candidate polymorphisms associated with differential response to anti-TNF treatment in rheumatoid arthritis.
Gaucher Disease
Severe systemic immune response syndrome, low plasma paraoxonase activity, and a new albumin species in a traumatized patient with Gaucher's disease.
Glaucoma
Decreased paraoxonase1 activity and increased malondialdehyde and oxidative DNA damage levels in primary open angle glaucoma.
Evaluation of oxidative stress and paraoxonase phenotypes in pseudoexfoliation syndrome and pseudoexfoliation glaucoma.
Higher serum lipids and oxidative stress in patients with normal tension glaucoma, but not pseudoexfoliative glaucoma.
Paraoxonase 1 (PON1) promoter (-107T/C) and coding region (192Q/R and 55L/M) genetic variations in pseudoexfoliation syndrome and pseudoexfoliative glaucoma risk.
Total oxidative stress, paraoxonase and arylesterase levels at patients with pseudoexfoliation syndrome and pseudoexfoliative glaucoma.
Glaucoma, Open-Angle
Decreased paraoxonase1 activity and increased malondialdehyde and oxidative DNA damage levels in primary open angle glaucoma.
Paraoxonase 1 gene polymorphisms influence clinical features of open-angle glaucoma.
Glioblastoma
Valproic acid inhibits glioblastoma multiforme cell growth via paraoxonase 2 expression.
Glioma
Paraoxonase 192 gene polymorphism and serum paraoxonase activity in high grade gliomas and meningiomas.
The Paraoxonase 1 Gene c.-108C>T SNP in the Promoter Is Associated with Risk for Glioma in Mexican Patients, but Not the p.L55M or p.Q192R Polymorphisms in the Coding Region.
Glomerulonephritis
Paraoxonase 1 polymorphisms in patients with primary glomerulonephritis: a single-center study in Turkey.
Paraoxonase activity in glomerulonephritic patients.
Glomerulonephritis, IGA
Paraoxonase gene polymorphism and serum activity in progressive IgA nephropathy.
Glomerulonephritis, Membranoproliferative
Is paraoxonase 192 gene polymorphism a risk factor for membranoproliferative glomerulonephritis in children?
Glomerulosclerosis, Focal Segmental
Genetic polymorphism in paraoxonase is a risk factor for childhood focal segmental glomerulosclerosis.
Glucose Intolerance
Adaptive response of rat pancreatic ?-cells to insulin resistance induced by monocrotophos: Biochemical evidence.
Effect of taurine supplementation on hyperhomocysteinemia and markers of oxidative stress in high fructose diet induced insulin resistance.
Serum oxidized low density lipoprotein, paraoxonase 1 and lipid peroxidation levels during oral glucose tolerance test.
glucose-6-phosphate dehydrogenase (nadp+) deficiency
Genetic polymorphisms in paraoxonase 1 and G protein-coupled receptor 77, and the risk of glucose-6-phosphate dehydrogenase deficiency in a Saudi population.
Glucosephosphate Dehydrogenase Deficiency
Genetic polymorphisms in paraoxonase 1 and G protein-coupled receptor 77, and the risk of glucose-6-phosphate dehydrogenase deficiency in a Saudi population.
Gout
Plasma Paraoxonase-1, Oxidized Low-Density Lipoprotein and Lipid Peroxidation Levels in Gout Patients.
Head and Neck Neoplasms
Serum Paraoxonase-1-Related Variables and Lipoprotein Profile in Patients with Lung or Head and Neck Cancer: Effect of Radiotherapy.
Hearing Loss, Noise-Induced
Association between Paraoxonase 2 Gene Polymorphisms and Noise-induced Hearing Loss in the Chinese Population.
Paraoxonase 3 gene polymorphisms are associated with occupational noise-induced deafness: A matched case-control study from China.
Paraoxonase and superoxide dismutase gene polymorphisms and noise-induced hearing loss.
Hearing Loss, Sensorineural
Prognostic value of serum anti-heat-shock protein 70 and paraoxonase levels in idiopathic sudden sensorineural hearing loss.
The relationship between thiol-disulfide balance and idiopathic sudden sensorineural hearing loss.
Heart Diseases
Decreased paraoxonase and arylesterase activities in the pathogenesis of future atherosclerotic heart disease in women with gestational diabetes mellitus.
Effects of paraoxonase 1 gene polymorphisms on heart diseases: Systematic review and meta-analysis of 64 case-control studies.
HDL associated paraoxonase-1 activity correlates with systemic inflammation, disease activity and cardiovascular risk factors in psoriatic disease.
Immunobiochemical analysis of Paraoxonase1 (anti-oxidant), xanthine oxidase (oxidant) enzymes and lipid profile of cardiac disease patients in Lahore Metropolitan, Pakistan.
Independent predictive roles of eotaxin Ala23Thr, paraoxonase 2 Ser311Cys and beta-adrenergic receptor Trp64Arg polymorphisms on cardiac disease in Type 2 Diabetes--an 8-year prospective cohort analysis of 1297 patients.
Paraoxonase PON1 polymorphism leu-Met54 is associated with carotid atherosclerosis: results of the Austrian Stroke Prevention Study.
Phenotype distribution of the paraoxonase gene in patients with cardiac disease.
The paraoxonase Gln-Arg 192 polymorphism in subjects with ischaemic heart disease.
[Age related decrease of high density lipoproteins (HDL) in women after menopause. Quantification of HDL with genetically determined HDL arylesterase in women with healthy coronary vessels and in women with angiographically verified coronary heart disease]
Heart Failure
High-density lipoprotein-associated paraoxonase-1 activity for prediction of adverse outcomes in outpatients with chronic heart failure.
Paraoxonase 2 prevents the development of heart failure.
[Congestive heart failure and paraoxonase]
Heart Failure, Systolic
Diminished antioxidant activity of high-density lipoprotein-associated proteins in systolic heart failure.
Relationship of High-Density Lipoprotein-Associated Arylesterase Activity to Systolic Heart Failure in Patients with and without Type 2 Diabetes.
Hemangioma, Cavernous, Central Nervous System
GLYOXALASE I A111E, PARAOXONASE 1 Q192R AND L55M POLYMORPHISMS IN ITALIAN PATIENTS WITH SPORADIC CEREBRAL CAVERNOUS MALFORMATIONS: A PILOT STUDY.
Hemochromatosis
Paraoxonase-1 status in patients with hereditary hemochromatosis.
Hemorrhagic Fever, Crimean
Effects of Paraoxonase-1 variants on course of severity and mortality of Crimean-Congo hemorrhagic fever.
Hemorrhagic Stroke
Apolipoprotein A-I and Paraoxonase-1 Are Potential Blood Biomarkers for Ischemic Stroke Diagnosis.
Hepatitis
Paraoxonase-1 activity is related to Trichinella spiralis-induced hepatitis in rats.
[Enteric sorbents potentiate hepatoprotective effect of eplir in experimental toxic hepatitis]
[Oxidative stress and semen parameters in the serum and seminal plasma of infertile men with chronic viral hepatitis].
[Serum arylesterase activity in patients with acute viral hepatitis]
Hepatitis B
Association of Paraoxonase 1 Gene Polymorphisms With the Risk of Hepatitis B Virus-related Liver Diseases in a Guangxi Population: A Case-control Study.
Serum lactonase and arylesterase activities in alcoholic hepatitis and hepatitis B.
Serum paraoxonase and arylesterase activities in various forms of hepatitis B virus infection.
Hepatitis B, Chronic
Association of paraoxonase activity and atherosclerosis in patients with chronic hepatitis B.
Maternal chronic hepatitis B virus is implicated with low neonatal paraoxonase/arylesterase activities.
Hepatitis C
Oxidant and antioxidant of arylesterase and paraoxonase as biomarkers in patients with hepatitis C virus.
Paraoxonase 1 gene (PON1) variants concerning hepatitis C virus (HCV) spontaneous clearance in hemodialysis individuals: a case-control study.
PON1 status in haemodialysis patients and the impact of hepatitis C infection.
Hepatitis C, Chronic
Genetic association of paraoxonase-1 polymorphisms and chronic hepatitis C virus infection.
[Investigation of the association between paraoxonase-1 gene polymorphisms and response to therapy in chronic hepatitis C patients].
Hepatitis, Alcoholic
Serum lactonase and arylesterase activities in alcoholic hepatitis and hepatitis B.
Hepatitis, Chronic
Genetic association of paraoxonase-1 polymorphisms and chronic hepatitis C virus infection.
Paraoxonase-1 is associated with oxidative stress, fibrosis and FAS expression in chronic liver diseases.
Serum arylesterase and paraoxonase activity in patients with chronic hepatitis.
Serum arylesterase isoenzymes in chronic hepatitis.
Serum Basal Paraoxonase 1 Activity as an Additional Liver Function Test for the Evaluation of Patients with Chronic Hepatitis.
Serum paraoxonase and arylesterase activities for the evaluation of patients with chronic hepatitis.
[Proceedings: Correlation between histological data and arylesterase isoenzyme behavior in chronic hepatitis]
Hepatomegaly
[Serum cholinesterase and arylesterase in cirrhosis and steatosic hepatomegaly]
Hepatopulmonary Syndrome
Nitric oxide metabolites, nitrative stress, and paraoxonase activity in hepatopulmonary syndrome.
HIV Infections
Serum paraoxonase-1 activity and concentration are influenced by human immunodeficiency virus infection.
Homocystinuria
Lipid, Oxidative and Inflammatory Profile and Alterations in the Enzymes Paraoxonase and Butyrylcholinesterase in Plasma of Patients with Homocystinuria Due CBS Deficiency: The Vitamin B12 and Folic Acid Importance.
Paraoxonase-1 expression is up-regulated in Down syndrome fetal liver.
Hydatidiform Mole
No association between serum paraoxonase, arylesterase activities, and hydatidiform mole.
Hyperandrogenism
Association of the polycystic ovary syndrome with genomic variants related to insulin resistance, type 2 diabetes mellitus, and obesity.
The role of chronic inflammation and Leu55Met PON1 polymorphism in the pathogenesis of polycystic ovary syndrome.
Hypercholesterolemia
Anthocyanin supplementation improves HDL-associated paraoxonase 1 activity and enhances cholesterol efflux capacity in subjects with hypercholesterolemia.
Atherosclerotic cardiovascular disease in women with endometriosis: a systematic review of risk factors and prospects for early surveillance.
Bovine lactoferrin ameliorates antioxidant esterase activity and 8-isoprostane levels in high-cholesterol-diet fed rats.
Decreased macrophage paraoxonase 2 expression in patients with hypercholesterolemia is the result of their increased cellular cholesterol content: effect of atorvastatin therapy.
Effect of taurine supplementation on hyperhomocysteinemia and markers of oxidative stress in high fructose diet induced insulin resistance.
Genetic risk for restenosis after coronary balloon angioplasty.
Oxysterols Increase Inflammation, Lipid Marker Levels and Reflect Accelerated Endothelial Dysfunction in Experimental Animals.
Hyperemesis Gravidarum
Paraoxonase-1 activity in patients with hyperemesis gravidarum.
Serum lipid profile, oxidative status, and paraoxonase 1 activity in hyperemesis gravidarum.
Hyperglycemia
An aqueous extract of Murraya koenigii leaves induces paraoxonase 1 activity in streptozotocin induced diabetic mice.
Effect of insulin resistance on serum paraoxonase activity in a nondiabetic population.
Glabridin, an isoflavan from licorice root, upregulates paraoxonase 2 expression under hyperglycemia and protects it from oxidation.
Serum oxidized low density lipoprotein, paraoxonase 1 and lipid peroxidation levels during oral glucose tolerance test.
The anti-inflammatory function of HDL is impaired in type 2 diabetes: role of hyperglycemia, paraoxonase-1 and low grade inflammation.
[Fish by-products oil corrects dyslipidemia, improves reverse cholesterol transport and stimulates paraoxonase-1 activity in obese rat].
[Relationships between PON1 L55M polymorphism and coronary heart diseases complicated with fasting hyperglycemia in Han populations in Guangdong]
Hyperhomocysteinemia
Altered gene expression in liver from a murine model of hyperhomocysteinemia.
Atherogenesis: hyperhomocysteinemia interactions with LDL, macrophage function, paraoxonase 1, and exercise.
Corrective effects of hepatotoxicity by hepatic Dyrk1a gene delivery in mice with intermediate hyperhomocysteinemia.
Effect of red wine polyphenol dietary supplementation on two phase II enzymes in liver of hyperhomocysteinemic mice.
Effect of taurine supplementation on hyperhomocysteinemia and markers of oxidative stress in high fructose diet induced insulin resistance.
Effects of catechin on homocysteine metabolism in hyperhomocysteinemic mice.
Effects of red wine polyphenolic compounds on paraoxonase-1 and lectin-like oxidized low-density lipoprotein receptor-1 in hyperhomocysteinemic mice.
Hyperhomocysteinemia, paraoxonase activity and risk of coronary artery disease.
Hyperhomocysteinemia, paraoxonase concentration and cardiovascular complications in Tunisian patients with nondiabetic renal disease.
Mouse liver paraoxonase-1 gene expression is downregulated in hyperhomocysteinemia.
Paraoxonase 1 and dietary hyperhomocysteinemia modulate the expression of mouse proteins involved in liver homeostasis.
Paraoxonase 1 deficiency and hyperhomocysteinemia alter the expression of mouse kidney proteins involved in renal disease.
Paraoxonase-1 activity determination via paraoxon substrate yields no significant difference in mild hyperhomocysteinemia.
Paraoxonase-1 expression is up-regulated in Down syndrome fetal liver.
Role of Genetic Background in Cardiovascular Risk Markers Changes in Water Polo Players.
Hyperinsulinism
Adaptive response of rat pancreatic ?-cells to insulin resistance induced by monocrotophos: Biochemical evidence.
Effect of insulin resistance on serum paraoxonase activity in a nondiabetic population.
Hyperlipidemia, Familial Combined
An omega-3 polyunsaturated fatty acid concentrate increases plasma high-density lipoprotein 2 cholesterol and paraoxonase levels in patients with familial combined hyperlipidemia.
Associations between HDL oxidation and paraoxonase-1 and paraoxonase-1 gene polymorphisms in families affected by familial combined hyperlipidemia.
Paraoxonase (PON1) is associated with familial combined hyperlipidemia.
Hyperlipidemias
An omega-3 polyunsaturated fatty acid concentrate increases plasma high-density lipoprotein 2 cholesterol and paraoxonase levels in patients with familial combined hyperlipidemia.
Associations between HDL oxidation and paraoxonase-1 and paraoxonase-1 gene polymorphisms in families affected by familial combined hyperlipidemia.
Can Carob-Fruit-Extract-Enriched Meat Improve the Lipoprotein Profile, VLDL-Oxidation, and LDL Receptor Levels Induced by an Atherogenic Diet in STZ-NAD-Diabetic Rats?
Elevated HDL2-paraoxonase and reduced CETP activity are associated with a dramatically lower ratio of LDL-cholesterol/total cholesterol in a hypercholesterolemic and hypertriglyceridemic patient.
Hyperlipidemia-induced hepatic and small intestine ER stress and decreased paraoxonase 1 expression and activity is associated with HDL dysfunction in Syrian hamsters.
Paraoxonase (PON1) is associated with familial combined hyperlipidemia.
Paraoxonase and arylesterase activities in stent restenosis in bare metal stent.
Paraoxonase-1 deficiency in mice predisposes to vascular inflammation, oxidative stress, and thrombogenicity in the absence of hyperlipidemia.
Single intravenous injection of plasmid DNA encoding human paraoxonase-1 inhibits hyperlipidemia in rats.
The effect of fenofibrate on serum paraoxonase activity and inflammatory markers in patients with combined hyperlipidemia.
The effect of red grape seed extract on serum paraoxonase activity in patients with mild to moderate hyperlipidemia.
Hyperlipoproteinemia Type II
Decrease of serum paraoxonase activity in chronic renal failure.
Decreased serum PON1 arylesterase activity in familial hypercholesterolemia patients with a mutated LDLR gene.
Erratum: Decreased serum PON1 arylesterase activity in familial hypercholesterolemia patients with a mutated LDLR gene.
Indications that paraoxonase-1 contributes to plasma high density lipoprotein levels in familial hypercholesterolemia.
Paraoxonase gene polymorphisms are associated with carotid arterial wall thickness in subjects with familial hypercholesterolemia.
Paraoxonase genotype and carotid intima-media thickness in children with familial hypercholesterolemia.
Paraoxonase-1 and linoleic acid oxidation in familial hypercholesterolemia.
Variation at the paraoxonase gene locus contributes to carotid arterial wall thickness in subjects with familial hypercholesterolemia.
Hyperlipoproteinemias
Changes in paraoxonase and apolipoprotein A-I, B, C-III and E in subjects with combined familiar hyperlipoproteinemia treated with ciprofibrate.
Hypertension
Atherosclerotic cardiovascular disease in women with endometriosis: a systematic review of risk factors and prospects for early surveillance.
Distribution of Paraoxonase-1 (PON-1) and Lipoprotein Phospholipase A2 (Lp-PLA2) across Lipoprotein Subclasses in Subjects with Type 2 Diabetes.
Effect of valsartan, an angiotensin II receptor blocker, on markers of oxidation and glycation in Japanese type 2 diabetic subjects: blood pressure-independent effect of valsartan.
Genetic background in apolipoprotein A-I and cystathionine beta-synthase deficiency.
Genetic risk for restenosis after coronary balloon angioplasty.
HDL associated paraoxonase-1 activity correlates with systemic inflammation, disease activity and cardiovascular risk factors in psoriatic disease.
Hypertension in children (12-14 years)--a case-control study in Bursa, Turkey.
Identification of differential gene expression profile from peripheral blood cells of military pilots with hypertension by RNA sequencing analysis.
Oxidative stress in white coat hypertension; role of paraoxonase.
Paraoxonase (PON1) 55 Polymorphism and Association with Systemic Lupus Erythematosus.
Paraoxonase and arylesterase activities in dipper and non-dipper prehypertensive subjects.
Paraoxonase and arylesterase activities in stent restenosis in bare metal stent.
Roles of Paraoxonase and Oxidative Stress in Adolescents with Uraemic, Essential or Obesity-Induced Hypertension.
The inverse association of HDL-cholesterol with future risk of hypertension is not modified by its antioxidant constituent, paraoxonase-1: The PREVEND prospective cohort study.
The paraoxonase Gln-Arg 192 polymorphism in subjects with ischaemic heart disease.
The PON1192RR genotype is associated with a higher prevalence of arterial hypertension.
Hyperthyroidism
Association between thyroid function and lipid profiles, apolipoproteins, and high-density lipoprotein function.
Hypertriglyceridemia
Effect of taurine supplementation on hyperhomocysteinemia and markers of oxidative stress in high fructose diet induced insulin resistance.
Interrelationships of serum paraoxonase, serum lipids and apolipoproteins in normal pregnancy. A longitudinal study.
Paraoxonase 1 and platelet-activating factor acetylhydrolase activities in patients with low hdl-cholesterol levels with or without primary hypertriglyceridemia.
The BB-paraoxonase genotype is associated with impaired brachial reactivity after acute hypertriglyceridemia in healthy subjects.
[The paraoxonase Gln-Arg 192 polymorphism in patients with endogenous hypertriglyceridemia in Chinese population]
Hypoalbuminemia
Serum esterase activity in reactive systemic amyloidosis and its relation to amyloid A degrading activity.
Hypoalphalipoproteinemias
Paraoxonase-1 activities in individuals with different HDL circulating levels: Implication in reverse cholesterol transport and early vascular damage.
Targeted Proteomics Identifies Paraoxonase/Arylesterase 1 (PON1) and Apolipoprotein Cs as Potential Risk Factors for Hypoalphalipoproteinemia in Diabetic Subjects Treated with Fenofibrate and Rosiglitazone.
Hypogonadism
The relationship between lipoprotein-associated phospholipase A2 with cardiovascular risk factors in testosterone deficiency.
Hypotension
Paraoxonase1 deficiency in mice is associated with hypotension and increased levels of 5,6-epoxyeicosatrienoic acid.
Hypothyroidism
Effect of levothyroxine replacement therapy on paraoxonase-1 and carotid intima-media thickness in subclinical hypothyroidism.
Effects of Short-Term Hypothyroidism on the Lipid Transfer to High-Density Lipoprotein and Other Parameters Related to Lipoprotein Metabolism in Patients Submitted to Thyroidectomy for Thyroid Cancer.
Evaluation of oxidative stress, the activities of paraoxonase and arylesterase in patients with subclinic hypothyroidism.
Evaluation of oxidative stress, the activities of paraoxonase and arylesterase in patients with subclinical hypothyroidism.
High-dose taurine supplementation increases serum paraoxonase and arylesterase activities in experimental hypothyroidism.
Levothyroxine improves Paraoxonase (PON-1) serum levels in patients with primary hypothyroidism: Case-control study.
Oxidative stress and enzymatic antioxidant status in patients with hypothyroidism before and after treatment.
Oxidative stress and serum paraoxonase activity in experimental hypothyroidism: effect of vitamin E supplementation.
Serum oxidative stress parameters of women with hypothyroidism.
Infections
A preliminary study of paraoxonase-1 in infected patients with an indwelling central venous catheter.
Airborne particulate matter PM2.5 from Mexico City affects the generation of reactive oxygen species by blood neutrophils from asthmatics: an in vitro approach.
Cardiovascular Insufficiency, Abdominal Sepsis, and Patients' Age Are Associated with Decreased Paraoxonase-1 (PON1) Activity in Critically Ill Patients with Multiple Organ Dysfunction Syndrome (MODS).
Decreased serum paraoxonase-1 activity during intestinal nematode (Nippostrongylus brasiliensis) infection in rats.
Effect of continuous renal-replacement therapy on paraoxonase-1-related variables in patients with acute renal failure caused by septic shock.
Effect of propolis and N-acetylcysteine supplementation on lipoprotein subclasses distribution and paraoxonase 1 activity in subjects with acute respiratory infection.
Expression of PPAR? and Paraoxonase 2 Correlated with Pseudomonas aeruginosa Infection in Cystic Fibrosis.
Genetic association of paraoxonase-1 polymorphisms and chronic hepatitis C virus infection.
High-density lipoprotein loses its anti-inflammatory properties during acute influenza a infection.
Human apolipoprotein AI mimetic peptides for the treatment of atherosclerosis.
Identification and analysis of the salt tolerant property of AHL lactonase (AiiATSAWB ) of Bacillus species.
Influenza infection promotes macrophage traffic into arteries of mice that is prevented by D-4F, an apolipoprotein A-I mimetic peptide.
Nippostrongylus brasiliensis: infection decreases plasma butyrylcholinesterase activity in rats.
Paraoxonase 1, Quorum Sensing, and P. aeruginosa Infection: A Novel Model.
Paraoxonase-1 activity is related to Trichinella spiralis-induced hepatitis in rats.
Plasma Paraoxonase, Sphingosine-1-phosphate, Total Sialic Acid, and Heat Shock Protein-27 in the Liver of the Sheep Naturally Infected with Cysticercus Tenuicollis: Evidence on Pathological Changes.
PON1 activity and total oxidant status in patients with active pulmonary tuberculosis.
PON1 status in haemodialysis patients and the impact of hepatitis C infection.
Preliminary study on serum paraoxonase-1 status and chemokine (C-C motif) ligand 2 in hospitalized elderly patients with catheter-associated asymptomatic bacteriuria.
Quantitative Proteomics and Lipidomics Analysis of Endoplasmic Reticulum of Macrophage Infected with Mycobacterium tuberculosis.
Schistosoma mansoni: Effect of dietary zinc supplement on egg granuloma in Swiss mice treated with praziqantel.
Serum ferritin and paraoxonase-1 in canine leishmaniosis.
Serum paraoxonase activity, total thiols levels, and oxidative status in patients with acute brucellosis.
Serum paraoxonase and arylesterase activities in various forms of hepatitis B virus infection.
Serum platelet-activating factor acetylhydrolase and paraoxonase-1 activity in horses infected with Leptospira spp.
The Sweat Metabolome of Screen-Positive Cystic Fibrosis Infants: Revealing Mechanisms beyond Impaired Chloride Transport.
Trichinella spiralis: infection changes serum paraoxonase-1 levels, lipid profile, and oxidative status in rats.
Trypanosoma congolense: paraoxonase 1 prolongs survival of infected mice.
Infertility
Gene-environment interactions: a review of effects on reproduction and development.
Serum tumor necrosis factor-?, interleukin-6, monocyte chemotactic protein-1 and paraoxonase-1 profiles in women with endometriosis, PCOS, or unexplained infertility.
Two new loci for hybrid sterility in cultivated rice (Oryza sativa L.).
Infertility, Female
Association between Serum Paraoxonase 1 Activities (PONase/AREase) and L55M Polymorphism in Risk of Female Infertility.
Paraoxonase-1 in female infertility: a possible role against oxidative stress-induced inflammation.
Infertility, Male
Paraoxonase-1 is only present in traceable amounts in seminal fluid and does not show any relationship with male subfertility.
[Clinical value of seminal paraoxonase-1 activity evaluation in the diagnosis of male infertility].
[Correlation of the single nucleotide polymorphism rs662 of PON1 with the risk of male infertility].
Inflammatory Bowel Diseases
Paraoxonase (PON)1 192R allele carriage is associated with reduced risk of inflammatory bowel disease.
Paraoxonase 1, 2 and 3 DNA variants and susceptibility to childhood inflammatory bowel disease.
Influenza, Human
High-density lipoprotein loses its anti-inflammatory properties during acute influenza a infection.
Human apolipoprotein AI mimetic peptides for the treatment of atherosclerosis.
Insulin Resistance
Adaptive response of rat pancreatic ?-cells to insulin resistance induced by monocrotophos: Biochemical evidence.
Adiponectin is a link among inflammation, insulin resistance, and high-density lipoprotein cholesterol but is not associated with paraoxonase activity in premenopausal women.
Association of paraoxonase-1 gene polymorphisms with insulin resistance in South Indian population.
Association of serum paraoxonase activity with insulin sensitivity and oxidative stress in hyperthyroid and TSH-suppressed nodular goitre patients.
Association of the polycystic ovary syndrome with genomic variants related to insulin resistance, type 2 diabetes mellitus, and obesity.
Associations of HDL phospholipids and paraoxonase activity with coronary heart disease in postmenopausal women.
Beneficial effect of low ethanol intake on the cardiovascular system: possible biochemical mechanisms.
Beneficial effects of curcumin on hyperlipidemia and insulin resistance in high-fat-fed hamsters.
Carotid artery intima media thickness associates with skin autofluoresence in non-diabetic subjects without clinically manifest cardiovascular disease.
CONDITIONING FACTORS FOR HIGH CARDIOVASCULAR RISK IN PATIENTS WITH CUSHING SYNDROME.
Diabetes and dyslipidaemia are associated with oxidative stress independently of inflammation in long-term antiretroviral-treated HIV-infected patients.
Effect of insulin resistance on serum paraoxonase activity in a nondiabetic population.
Effect of taurine supplementation on hyperhomocysteinemia and markers of oxidative stress in high fructose diet induced insulin resistance.
Hemodynamics and metabolism at low versus moderate altitudes.
Impaired paraoxonase-1 status in obese children. Relationships with insulin resistance and metabolic syndrome.
Increased low-density lipoprotein oxidation and impaired high-density lipoprotein antioxidant defense are associated with increased macrophage homing and atherosclerosis in dyslipidemic obese mice: LCAT gene transfer decreases atherosclerosis.
Paraoxonase-1 (PON1) Status in Pancreatic Cancer: Relation to Clinical Parameters.
Paraoxonase-1 is not affected in polycystic ovary syndrome without metabolic syndrome and insulin resistance, but oxidative stress is altered.
Paraoxonase1 (PON1) reduces insulin resistance in mice fed a high-fat diet, and promotes GLUT4 overexpression in myocytes, via the IRS-1/Akt pathway.
Pentoxifylline mitigates renal glycoxidative stress in obese mice by inhibiting AGE/RAGE signaling and increasing glyoxalase levels.
PON1-108 TT and PON1-192 RR genotypes are more frequently encountered in Greek PCOS than non-PCOS women, and are associated with hyperandrogenemia.
Q192R Paraoxonase (PON)1 Polymorphism, Insulin Sensitivity, and Endothelial Function in Essential Hypertensive Men.
Q192R Polymorphism of Paraoxonase 1 Gene Associated with Insulin Resistance in Mexican Children.
Role of Various Gene Expressions in Etiopathogenesis of Type 2 Diabetes Mellitus.
Serum paraoxonase-1 activity in children: the effects of obesity and insulin resistance.
Serum Paraoxonase-1 Levels are Significantly Decreased in the Presence of Insulin Resistance.
The effect of ginger (Zingiber officinale) on glycemic markers in patients with type 2 diabetes.
The effect of sumac (Rhus coriaria L.) powder on insulin resistance, malondialdehyde, high sensitive C-reactive protein and paraoxonase 1 activity in type 2 diabetic patients.
The paraoxonase PON1 promoter polymorphism C(-107)T is associated with increased serum glucose concentrations in non-diabetic patients.
The role of chronic inflammation and Leu55Met PON1 polymorphism in the pathogenesis of polycystic ovary syndrome.
[Combined analyses of paraoxonase-1 and IGF-2 polymorphism in polycystic ovary syndrome]
[Smoking enhances the decrease of adiponectin level in patients with coronary artery disease, carriers of MTHFR 677T and PON1 55M alleles].
Intervertebral Disc Degeneration
Paraoxonase 1 Was Negatively Associated With Intervertebral Disc Degeneration.
Iron Deficiencies
Reduced antioxidant capacity in children with iron deficiency and iron-deficiency anemia.
Irritable Bowel Syndrome
Evaluation of paraoxonase and arylesterase activities in patients with irritable bowel syndrome.
Ischemic Stroke
Analysis of paraoxonase 1 (PON1) genetic polymorphisms and activities as risk factors for ischemic stroke in Turkish population.
Apolipoprotein A-I and Paraoxonase-1 Are Potential Blood Biomarkers for Ischemic Stroke Diagnosis.
Association between paraoxonase 2 Ser311Cys polymorphism and ischemic stroke risk: a meta-analysis involving 5,008 subjects.
Decreased paraoxonase-1 activity is a risk factor for ischemic stroke in Koreans.
Genetic polymorphisms of Chinese patients with ischemic stroke and concurrent stenoses of extracranial and intracranial vessels.
Interaction of folate intake and the paraoxonase Q192R polymorphism with risk of incident coronary heart disease and ischemic stroke: the atherosclerosis risk in communities study.
Oxidative stress and paraoxonase 1 status in acute ischemic stroke patients.
Paraoxonase 1 and 2 gene variants and the ischemic stroke risk in Gran Canaria population: an association study and meta-analysis.
Paraoxonase 1 polymorphisms and ischemic stroke risk: A systematic review and meta-analysis.
Paraoxonase 192 Gln-->Arg polymorphism: an independent risk factor for nonfatal arterial ischemic stroke among young adults.
Paraoxonase gene polymorphisms and haplotype analysis in a stroke population.
Paraoxonase genes and the susceptibilty to ischemic stroke.
Paraoxonase-1 polymorphisms and cerebral ischemic stroke: a pilot study in mexican patients.
Paraoxonase/arylesterase ratio, PON1 192Q/R polymorphism and PON1 status are associated with increased risk of ischemic stroke.
Polymorphisms of MTHFR, eNOS, ACE, AGT, ApoE, PON1, PDE4D, and Ischemic Stroke: Meta-Analysis.
PON gene polymorphisms and ischaemic stroke: a systematic review and meta analysis.
Prognostic importance of paraoxonase, arylesterase and mean platelet volume efficiency in acute ischaemic stroke.
Rare coding variation in paraoxonase-1 is associated with ischemic stroke in the NHLBI Exome Sequencing Project.
Relation of Paraoxonase1, Arylesterase and Lipid Profile in Ischemic Stroke Patients.
Response to letter to the editor: paraoxonase genes and the susceptibility to ischemic stroke.
Serum paraoxonase/arylesterase activity affects outcome in ischemic stroke patients.
Sonographic evaluation of atherosclerosis burden in carotid arteries of ischemic stroke patients and its relation to paraoxonase 1 and 2, MTHFR and AT1R genetic variants.
The combined effect of paraoxonase promoter and coding region polymorphisms on the risk of arterial ischemic stroke among young adults.
[Relationship between Q192R polymorphisms in paraoxonase 1 gene and young ischemic stroke]
[The association of paraoxonase 2 gene C311S variant with ischemic stroke in Chinese type 2 diabetes mellitus patients]
[The effect of cigarette smoking on serum activities of paraoxonase and arylesterase in stroke patients]
Joint Diseases
HDL associated paraoxonase-1 activity correlates with systemic inflammation, disease activity and cardiovascular risk factors in psoriatic disease.
Keratoconus
Paraoxonase 1 status in keratoconus: a preliminary study of activity and polymorphism.
Ketosis
Predictive Value of Plasma Parameters in the Risk of Postpartum Ketosis in Dairy Cows.
Serum paraoxonase-1 activity in tail and mammary veins of ketotic dairy cows.
Kidney Diseases
Can keto/amino acids reduce oxidative stress in peritoneal dialysis patients with hypoalbuminemia?
Paraoxonase 1 deficiency and hyperhomocysteinemia alter the expression of mouse kidney proteins involved in renal disease.
Kidney Failure, Chronic
Acrolein inactivates paraoxonase 1: changes in free acrolein levels after hemodialysis correlate with increases in paraoxonase 1 activity in chronic renal failure patients.
Activity of paraoxonase 1 (PON1) on HDL2 and HDL3 subclasses in renal disease.
Decreased paraoxonase 1 (PON1) lactonase activity in hemodialyzed and renal transplanted patients. A novel cardiovascular biomarker in end-stage renal disease.
Effect of nutritional status on human paraoxonase-1 activity in patients with chronic kidney disease.
Increased carbamylation level of HDL in end-stage renal disease: carbamylated-HDL attenuated endothelial cell function.
Increased oxidized-LDL levels and arylesterase activity/HDL ratio in ESRD patients treated with hemodialysis.
Levels of asymmetric dimethylarginine, nitric oxide and lipid peroxidation markers in patients with end-stage renal disease having peritoneal dialysis treatment.
Low High-Density Lipoprotein Cholesterol Is Not Responsible for Decreased Paraoxonase Activity in Chronic Renal Failure.
Paraoxonase 1 in chronic kidney failure.
Paraoxonase activity and antibodies to oxidized-LDL in chronic renal failure patients on renal replacement therapy.
Paraoxonase activity stimulation by salts is higher in chronic renal failure patients than in controls.
Paraoxonase, anti-oxidant response and oxidative stress in children with chronic renal failure.
Paraoxonase-1 (PON1) activity as a risk factor for atherosclerosis in chronic renal failure patients.
Paraoxonase-1 and ischemia-modified albumin in patients with end-stage renal disease.
Paraoxonase-1 concentrations in end-stage renal disease patients increase after hemodialysis: correlation with low molecular AGE adduct clearance.
Paraoxonase: Its antiatherogenic role in chronic renal failure.
Renal cortical thickness and PON1 activity both decrease in chronic renal failure.
Salutary effects of hemodialysis on low-density lipoprotein proinflammatory and high-density lipoprotein anti-inflammatory properties in patient with end-stage renal disease.
Serum paraoxonase activity and protein thiols in chronic renal failure patients.
The free fraction of paraoxonase 1 is not increased in patients with end stage renal disease undergoing hemodialysis.
The Protective Role of Adiponectin for Lipoproteins in End-Stage Renal Disease Patients: Relationship with Diabetes and Body Mass Index.
The serum paraoxonase activity in patients with chronic renal failure and hyperlipidemia.
[From organophosphate compound toxicity to atherosclerosis: role of paraoxonase 1]
Language Development Disorders
Reevaluation of Serum Arylesterase Activity in Neurodevelopmental Disorders.
Laryngeal Neoplasms
Alterations in oxidative stress markers in laryngeal carcinoma patients.
Lecithin Cholesterol Acyltransferase Deficiency
Low A-esterase activity in serum of patients with fish-eye disease.
Targeted disruption of the murine lecithin:cholesterol acyltransferase gene is associated with reductions in plasma paraoxonase and platelet-activating factor acetylhydrolase activities but not in apolipoprotein J concentration.
Leiomyoma
Oxidative stress and prolidase activity in women with uterine fibroids.
Q192R variant in paraoxonase 1 gene confers susceptibility to leiomyoma.
Leishmaniasis
Influence of domperidone supplementation on short-term changes in C-reactive protein and paraoxonase-1 in dogs with leishmaniasis undergoing meglumine antimoniate and allopurinol therapy.
Paraoxonase activity as a tool for clinical monitoring of dogs treated for canine leishmaniasis.
Leukemia, Lymphocytic, Chronic, B-Cell
Paraoxonase 1 (PON1) Q192R and L55M Polymorphisms as Potential Predisposition Factors for Chronic Lymphocytic Leukemia.
Q192R and L55M Polymorphisms of Paraoxonase 1 Gene in Chronic Myelogenous Leukemia and Chronic Lymphocytic Leukemia.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Q192R and L55M Polymorphisms of Paraoxonase 1 Gene in Chronic Myelogenous Leukemia and Chronic Lymphocytic Leukemia.
Leukemia, Myeloid, Acute
The activities of serum paraoxonase and arylesterase and lipid profile in acute myeloid leukemia: preliminary results.
Lipid Metabolism Disorders
Association of a polymorphism in PON-1 gene with steroid-induced osteonecrosis of femoral head in Chinese Han population.
Lipodystrophy
Effects of rosiglitazone and metformin on postprandial paraoxonase-1 and monocyte chemoattractant protein-1 in human immunodeficiency virus-infected patients with lipodystrophy.
Liver Cirrhosis
2-Oxo-1,3-dioxoles as specific substrates for measurement of arylesterase activity.
Combination of serum paraoxonase/arylesterase 1 and antithrombin-III is a promising non-invasion biomarker for discrimination of AFP-negative HCC versus liver cirrhosis patients.
Cytokines, paraoxonase-1, periostin and non-invasive liver fibrosis scores in patients with non-alcoholic fatty liver disease and persistently elevated aminotransferases: A pilot study.
ELISA using monoclonal antibody to human serum arylesterase.
Paraoxonase-1 is associated with oxidative stress, fibrosis and FAS expression in chronic liver diseases.
Therapeutic HNF4A mRNA attenuates liver fibrosis in a preclinical model.
Liver Diseases
A targeted multi-omics approach reveals paraoxonase-1 as a determinant of obesity-associated fatty liver disease.
Açai (Euterpe oleracea Mart.) Upregulates Paraoxonase 1 Gene Expression and Activity with Concomitant Reduction of Hepatic Steatosis in High-Fat Diet-Fed Rats.
Association between moderately oxidized low-density lipoprotein and high-density lipoprotein particle subclass distribution in hemodialyzed and post-renal transplant patients.
Association of carotid intima media thickness with atherogenic index of plasma, apo B/apo A-I ratio and paraoxonase activity in patients with non-alcoholic fatty liver disease.
Association of Paraoxonase 1 Gene Polymorphisms With the Risk of Hepatitis B Virus-related Liver Diseases in a Guangxi Population: A Case-control Study.
Baseline and salt-stimulated paraoxonase and arylesterase activities in patients with chronic liver disease: relation to disease severity.
Baseline and Salt-stimulated Paraoxonase and Arylesterase Activities in Patients with Chronic Liver Disease: Relation with Disease Severity.
Chemokine ligand 2 and paraoxonase-1 in non-alcoholic fatty liver disease: The search for alternative causative factors.
Cytokines, paraoxonase-1, periostin and non-invasive liver fibrosis scores in patients with non-alcoholic fatty liver disease and persistently elevated aminotransferases: A pilot study.
Early effects of sodium valproate monotherapy on serum paraoxonase/arylesterase activities.
Interrelationships between paraoxonase-1 and monocyte chemoattractant protein-1 in the regulation of hepatic inflammation.
Involvement of xanthine oxidase and paraoxonase 1 in the process of oxidative stress in nonalcoholic fatty liver disease.
New chemiluminescent substrates of paraoxonase 1 with improved specificity: synthesis and properties.
Paraoxonase 1 and Non-Alcoholic Fatty Liver Disease: A Meta-Analysis.
Paraoxonase activity and expression is modulated by therapeutics in experimental rat nonalcoholic Fatty liver disease.
Paraoxonase activity in sera of patients with non-alcoholic fatty liver disease.
Paraoxonase-1 activity, malondialdehyde and glutathione peroxidase in non-alcoholic fatty liver disease and the effect of atorvastatin.
Paraoxonase-1 is associated with oxidative stress, fibrosis and FAS expression in chronic liver diseases.
Paraoxonase-1 is related to inflammation, fibrosis and PPAR delta in experimental liver disease.
Paraoxonase-1 Serum Concentration and PON1 Gene Polymorphisms: Relationship with Non-Alcoholic Fatty Liver Disease.
Serum esterase activity in reactive systemic amyloidosis and its relation to amyloid A degrading activity.
Serum lactonase and arylesterase activities in alcoholic hepatitis and hepatitis B.
Serum paraoxonase 1 activity is paradoxically maintained in nonalcoholic fatty liver disease despite low HDL cholesterol.
Serum paraoxonase activity and oxidative stress and their relationship with obesity-related metabolic syndrome and non-alcoholic fatty liver disease in obese children and adolescents.
Serum paraoxonase and arylesterase activities in Iranian patients with nonalcoholic fatty liver disease.
Serum paraoxonase levels in patients with acute liver disease.
Serum paraoxonase-1 in chronic alcoholics: relationship with liver disease.
Serum proteomic analysis of diet-induced steatohepatitis and metabolic syndrome in the Ossabaw miniature swine.
[Arylesterase isoenzymes in the diagnosis of liver diseases]
Liver Diseases, Alcoholic
Identification and preliminary validation of novel biomarkers of acute hepatic ischaemia/reperfusion injury using dual-platform proteomic/degradomic approaches.
Serum paraoxonase-1 in chronic alcoholics: relationship with liver disease.
Liver Neoplasms
Hypermethylation reduces the expression of PNPLA7 in hepatocellular carcinoma.
Transcriptomic characterization reveals prognostic molecular signatures of sorafenib resistance in hepatocellular carcinoma.
Low Tension Glaucoma
Higher serum lipids and oxidative stress in patients with normal tension glaucoma, but not pseudoexfoliative glaucoma.
Lung Diseases
Assessing the relationship of paraoxonase-1 Q192R polymorphisms and the severity of lung disease in SM-exposed patients.
Serum paraoxonase and arylesterase activities in patients with pulmonary tuberculosis.
Lung Neoplasms
Association of genetic polymorphisms in the paraoxonase 1 gene with the risk and prognosis of non-small cell lung cancer in chinese han population.
Interactions between Paraoxonase 1 Genetic Polymorphisms and Smoking and Their Effects on Oxidative Stress and Lung Cancer Risk in a Korean Population.
Paraoxonase-1 (PON1) induces metastatic potential and apoptosis escape via its antioxidative function in lung cancer cells.
Paraoxonase-1 192/55 polymorphisms and the risk of lung cancer in a Turkish population.
Serum paraoxonase and arylesterase activities in patients with lung cancer in a Turkish population.
Serum Paraoxonase-1-Related Variables and Lipoprotein Profile in Patients with Lung or Head and Neck Cancer: Effect of Radiotherapy.
[Effects of oxidative DNA damage induced by polycyclic aromatic hydrocarbons and genetic polymorphism of the paraoxonase-1 (PON1) gene on lung cancer]
Lupus Erythematosus, Systemic
Anti-apolipoprotein A-I antibodies and paraoxonase 1 activity in Systemic Lupus Erythematosus.
Antibodies to high-density lipoprotein and beta2-glycoprotein I are inversely correlated with paraoxonase activity in systemic lupus erythematosus and primary antiphospholipid syndrome.
Antibodies toward high-density lipoprotein components inhibit paraoxonase activity in patients with systemic lupus erythematosus.
Association between paraoxonase-1 gene Q192R and L55M polymorphisms in systemic lupus erythematosus (SLE) and anti-phospholipid syndrome (APS) in a population from Cairo of Egypt.
Associations between paraoxonase-1 and systemic lupus erythematosus.
Genetic variation in the paraoxonase-3 (PON3) gene is associated with serum PON1 activity.
High-density lipopoprotein antioxidant capacity, subpopulation distribution and paraoxonase-1 activity in patients with systemic lupus erythematosus.
Paraoxonase (PON1) 55 Polymorphism and Association with Systemic Lupus Erythematosus.
Reduced paraoxonase1 activity is a risk for atherosclerosis in patients with systemic lupus erythematosus.
Relationship of serum paraoxonase 1 activity and paraoxonase 1 genotype to risk of systemic lupus erythematosus.
Serum Levels of Anti-PON1 and Anti-HDL Antibodies as Potential Biomarkers of Premature Atherosclerosis in Systemic Lupus Erythematosus.
Synergism between apolipoprotein E ?4 allele and paraoxonase (PON1) 55-M allele is associated with risk of systemic lupus erythematosus.
Synergistic effects of BuChE non-UU phenotype and paraoxonase (PON1) 55 M allele on the risk of systemic lupus erythematosus: influence on lipid and lipoprotein metabolism and oxidative stress, preliminary report.
Lymphocytosis
Immunopotentiating activity of abrin, a lectin from Abrus precatorius Linn.
Macular Degeneration
Association between the L55M and Q192R polymorphisms of the paraoxonase-1 gene and age-related macular degeneration: a meta-analysis.
ASSOCIATION OF PARAOXONASE 1 L55M AND Q192R SINGLE-NUCLEOTIDE POLYMORPHISMS WITH AGE-RELATED MACULAR DEGENERATION.
Association of the M55L and Q192R paraoxonase gene polymorphisms with age-related macular degeneration.
Paraoxonase gene polymorphisms and plasma oxidized low-density lipoprotein level as possible risk factors for exudative age-related macular degeneration.
Protective effect of paraoxonase 1 gene variant Gln192Arg in age-related macular degeneration.
Regulatory regions of the paraoxonase 1 (PON1) gene are associated with neovascular age-related macular degeneration (AMD).
Serum paraoxonase 1 activity and lipid peroxidation levels in patients with age-related macular degeneration.
Malnutrition
Leptin and adiponectin as new markers of undernutrition in cancer.
Paraoxonase, total antioxidant activity and peroxide levels in marasmic children: relationships with leptin.
Mania
Towards a new model and classification of mood disorders based on risk resilience, neuro-affective toxicity, staging, and phenome features using the nomothetic network psychiatry approach.
Mastitis
Paraoxonase 1 in bovine milk and blood as marker of subclinical mastitis caused by Staphylococcus aureus.
Relationship between California mastitis test reaction and leucocyte count, catalase activity, and A-esterase activity of milk from opposite quarters.
Meningioma
Paraoxonase 192 gene polymorphism and serum paraoxonase activity in high grade gliomas and meningiomas.
Two common nonsynonymous paraoxonase 1 (PON1) gene polymorphisms and brain astrocytoma and meningioma.
Mesenteric Ischemia
Early Elevation of Cell-free DNA After Acute Mesenteric Ischemia in Rats.
Metabolic Syndrome
ABCA1 gene R1587K polymorphism could be associated with metabolic syndrome and increased plasma triglyceride concentration in adults from northern Mexico.
Antioxidant paraoxonase 1 activity in the metabolic syndrome.
Arylesterase activity is associated with antioxidant intake and paraoxonase-1 (PON1) gene methylation in metabolic syndrome patients following an energy restricted diet.
Association between paraoxonase-1 gene polymorphisms and risk of metabolic syndrome.
Carotid artery intima media thickness associates with skin autofluoresence in non-diabetic subjects without clinically manifest cardiovascular disease.
Ciprofibrate increases paraoxonase activity in patients with metabolic syndrome.
Circulating levels of adiponectin, orexin-A, ghrelin and the antioxidant paraoxonase-1 in metabolic syndrome.
Cross-sectional correlates of paraoxonase 1 and soluble intercellular adhesion molecule-1 in metabolic syndrome patients with and without diabetes.
Does metformin increase paraoxonase activity in patients with the metabolic syndrome? Additional data from the MEFISTO study.
HDL associated paraoxonase-1 activity correlates with systemic inflammation, disease activity and cardiovascular risk factors in psoriatic disease.
Human paraoxonase-1 overexpression inhibits atherosclerosis in a mouse model of metabolic syndrome.
Impaired paraoxonase-1 status in obese children. Relationships with insulin resistance and metabolic syndrome.
Lower serum paraoxonase-1 activity is related to higher serum amyloid a levels in metabolic syndrome.
Non-diabetic metabolic syndrome and obesity do not affect serum paraoxonase and arylesterase activities but do affect oxidative stress and inflammation.
Paraoxonase (PON)1 Q192R functional genotypes and PON1 Q192R genotype by smoking interactions are risk factors for the metabolic syndrome, but not overweight or obesity.
Paraoxonase 1 (PON1) in French HIV-Infected Patients under Antiretroviral Therapy: Relationship with the Metabolic Syndrome and Inflammation.
Paraoxonase 1 genotype-phenotype correlation in patients with metabolic syndrome.
Paraoxonase activity in metabolic syndrome in children and adolescents.
Paraoxonase responses to exercise and niacin therapy in men with metabolic syndrome.
Paraoxonase-1 is not affected in polycystic ovary syndrome without metabolic syndrome and insulin resistance, but oxidative stress is altered.
Paraoxonase-1 promoter polymorphism C--107T and serum apolipoprotein AI interact to modulate serum paraoxonase-1 status.
Persistent elevation of paraoxonase-1 specific enzyme activity after weight reduction in obese non-diabetic men with metabolic syndrome.
Positive correlation of paraoxonase 1 (PON1) activity with serum insulin level and HOMA-IR in dementia. A possible advantageous role of PON1 in dementia development.
Serum paraoxonase activity and oxidative stress and their relationship with obesity-related metabolic syndrome and non-alcoholic fatty liver disease in obese children and adolescents.
Serum paraoxonase and arylesterase activities in metabolic syndrome in Zahedan, southeast Iran.
Serum paraoxonase-1 activities and oxidative status in patients with plaque-type psoriasis with/without metabolic syndrome.
Serum paraoxonase/arylesterase activity and oxidative stress status in children with metabolic syndrome.
Small, dense lipoprotein particles and reduced paraoxonase-1 in patients with the metabolic syndrome.
Soft drink consumption is associated with fatty liver disease independent of metabolic syndrome.
The positive relationship of serum paraoxonase-1 activity with apolipoprotein E is abrogated in metabolic syndrome.
The relationship between paraoxonase-1 activity and coronary artery disease in patients with metabolic syndrome.
[Sedentary lifestyle: physical activity duration versus percentage of energy expenditure]
Microvascular Angina
Paraoxonase and arylesterase activities in patients with cardiac syndrome X, and their relationship with oxidative stress markers.
Migraine Disorders
Paraoxonase 1 (PON1) polymorphisms and risk for migraine.
Paraoxonase 1 gene polymorphisms, paraoxonase/arylesterase activities and oxidized low-density lipoprotein levels in patients with migraine.
Mixed Connective Tissue Disease
Endothelial cell markers reflecting endothelial cell dysfunction in patients with mixed connective tissue disease.
Evaluation of paraoxonase activity in patients with mixed connective tissue disease.
Increased levels of anti-heat-shock protein 60 (anti-Hsp60) indicate endothelial dysfunction, atherosclerosis and cardiovascular diseases in patients with mixed connective tissue disease.
Motor Neuron Disease
Neuropathy target esterase gene mutations cause motor neuron disease.
Rare and common paraoxonase gene variants in amyotrophic lateral sclerosis patients.
Multiple Myeloma
Associations of common variants in genes involved in metabolism and response to exogenous chemicals with risk of multiple myeloma.
Decreased HDL-dependent paraoxonase and arylesterase enzyme activity may indicate a worse prognosis in multiple myeloma.
Serum 8-isoprostane levels and paraoxonase 1 activity in patients with stage I multiple myeloma.
Multiple Sclerosis
Association between serum paraoxonase 1 activity and its polymorphisms with multiple sclerosis: a systematic review.
Increased levels of lipid hydroperoxides in plasma of patients with multiple sclerosis: a relationship with paraoxonase activity.
Lack of association between paraoxonase 1 Q192R polymorphism and multiple sclerosis in relapse phase: A case-control study.
Paraoxonase 1 activity in different types of multiple sclerosis.
Paraoxonase 1 activity in multiple sclerosis patients during mitoxantrone therapy.
Paraoxonase 1 Polymorphisms Are Not Related with the Risk for Multiple Sclerosis.
Polymorphisms of paraoxonase 1 and 2 genes and the risk of multiple sclerosis in the Polish population.
Serum paraoxonase and arylesterase activity and oxidative status in patients with multiple sclerosis.
Multiple Sclerosis, Relapsing-Remitting
Serum paraoxonase and arylesterase activity and oxidative status in patients with multiple sclerosis.
Muscular Diseases
Histopathology is required to identify and characterize myopathies in high-throughput phenotype screening of genetically engineered mice.
[Muscular, plasma and globular cholinesterases and arylesterase in experimental myopathy in rabbits due to diet deficient in choline]
Myocardial Infarction
Acetylcholine esterase protects LDL against oxidation.
Addressing the link between paraoxonase-1 gene variants and the incidence of early onset myocardial infarction.
Association between paraoxonase-1 and paraoxonase-2 polymorphisms and the risk of acute myocardial infarction.
Cardiovascular risk factors in elderly normolipidemic acute myocardial infarct patients--a case controlled study from India.
Characterization of paraoxonase activity in pericardial fluid: usefulness as a marker of coronary disease.
Clinical and Genetic Association of Serum Paraoxonase and Arylesterase Activities With Cardiovascular Risk.
Decrease of serum paraoxonase activity in chronic renal failure.
Differential effects of smoking on myocardial infarction risk according to the Gln/Arg 192 variants of the human paraoxonase gene.
Distribution of paraoxon hydrolytic activity in the serum of patients after myocardial infarction.
Effect of paraoxonase-1 polymorphism on clinical outcomes in patients treated with clopidogrel after an acute myocardial infarction.
Interactions and associations of paraoxonase gene cluster polymorphisms with myocardial infarction in a Pakistani population.
Oxidative Stress and Paraoxonase 1 Activity Predict Contrast-Induced Nephropathy in Patients With ST-Segment Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention.
Paraoxonase (PON1) and the risk for coronary heart disease and myocardial infarction in a general population of Dutch women.
Paraoxonase (PON1) Gene Polymorphisms in Fabry Disease: Correlation with Renal Disease.
Paraoxonase 1 gene Q192R polymorphism affects stroke and myocardial infarction risk.
Paraoxonase 1 Polymorphisms and Risk of Myocardial Infarction in Women and Men.
Paraoxonase 192 Gln/Arg gene polymorphism, coronary artery disease, and myocardial infarction in type 2 diabetes.
Paraoxonase gene Q192R & L55M polymorphisms in Indians with acute myocardial infarction & association with oxidized low density lipoprotein.
Paraoxonase Gln-Arg(192) and Leu-Met(55) gene polymorphisms and enzyme activity in a population with a low rate of coronary heart disease.
Paraoxonase-1 55 LL Genotype Is Associated with No ST-Elevation Myocardial Infarction and with High Levels of Myoglobin.
Paraoxonase-1 activity and oxidative stress in patients with anterior ST elevation myocardial infarction undergoing primary percutaneous coronary intervention with and without no-reflow.
Polymorphism in high density lipoprotein paraoxonase gene and risk of acute myocardial infarction in men: prospective nested case-control study.
Polymorphisms in the paraoxonase and endothelial nitric oxide synthase genes and the risk of early-onset myocardial infarction.
Relationship between Paraoxonase-1 and Arylesterase Enzyme Activities and SYNTAX I and II Scores in Patients with ST-Elevation Myocardial Infarction.
Relationship of age-related myocardial infarction risk and Gln/Arg 192 variants of the human paraoxonase1 gene: the REGICOR study.
Risk of myocardial infarction associated with Gln/Arg 192 polymorphism in the human paraoxonase gene and diabetes mellitus. The REGICOR Investigators.
Serum arylesterase (paraoxonase) activity following myocardial infarction.
Smoking is associated with reduced serum paraoxonase, antioxidants and increased oxidative stress in normolipidaemic acute myocardial infarct patients.
The Gln/Arg polymorphism of human paraoxonase (PON 192) is not related to myocardial infarction in the ECTIM Study.
The influence of renal function on the association of rs854560 polymorphism of paraoxonase 1 gene with long-term prognosis in patients after myocardial infarction.
The paraoxonase Gln-Arg 192 polymorphism in subjects with ischaemic heart disease.
The paraoxonase L55M and Q192R gene polymorphisms and myocardial infarction in a Tunisian population.
Tobacco smoking modifies association between Gln-Arg192 polymorphism of human paraoxonase gene and risk of myocardial infarction.
[Association between paraoxonase-1 and paraoxonase-2 polymorphisms and the risk of acute myocardial infarction]
[Genetic risk factors for development of myocardial infarction in young men living in North-West region of Russia]
Myocardial Ischemia
Cytochrome 2C19 and paraoxonase-1 polymorphisms and clopidogrel resistance in ischemic heart disease patients.
Effect of statins on serum apolipoprotein j and paraoxonase-1 levels in patients with ischemic heart disease undergoing coronary angiography.
Ischemic heart disease as deficiency disease.
Paraoxonase activity following exercise-based cardiac rehabilitation program.
Paraoxonase1, its Q192R polymorphism and HDL-cholesterol in relation to intensive cardiac care unit stay in ischemic heart disease.
Nasal Polyps
Serum paraoxonase, arylesterase activity, and oxidative status in patients with nasal polyp.
Nematode Infections
An atherogenic lipid profile with low serum paraoxonase-1 activity during nematode infection in rats.
Decreased serum paraoxonase-1 activity during intestinal nematode (Nippostrongylus brasiliensis) infection in rats.
Neonatal Sepsis
Total Antioxidan Level, Total Oxidan Level and Serum Paraoxonase-1 Levels in Neonatal Sepsis.
Neoplasm Metastasis
Adenocarcinoma of the colon with choriocarcinoma in its metastases.
Collapsing the Metabolic PON2zi Scheme in Pancreatic Ductal Adenocarcinoma.
Evaluation of the prognostic value of paraoxonase 1 in the recurrence and metastasis of hepatocellular carcinoma and establishment of a liver-specific predictive model of survival.
Paraoxonase 2 Facilitates Pancreatic Cancer Growth and Metastasis by Stimulating GLUT1-Mediated Glucose Transport.
Neoplasms
A meta-analysis of the relationship between paraoxonase 1 polymorphisms and cancer.
Accelerated atherosclerosis in rheumatoid arthritis.
Age-Related Adverse Inflammatory and Metabolic Changes Begin Early in Adulthood.
Ambient ultrafine particles alter lipid metabolism and HDL anti-oxidant capacity in LDLR-null mice.
Arylesterase isoenzymes and activity in normal healthy adults and in patients with cancer and with other diseases.
Association between inflammatory markers and serum paraoxonase and arylesterase activities in the general population: a cross-sectional study.
Association between L55M polymorphism in Paraoxonase 1 and cancer risk: a meta-analysis based on 21 studies.
Association between moderately oxidized low-density lipoprotein and high-density lipoprotein particle subclass distribution in hemodialyzed and post-renal transplant patients.
Association of cadmium, lead and mercury with paraoxonase 1 activity in women.
Association of candidate gene polymorphisms with diabetic retinopathy in Chinese patients with type 2 diabetes.
Association of L55M and Q192R polymorphisms in paraoxonase 1 (PON1) gene with breast cancer risk and their clinical significance.
Association of Paraoxonase 1 Gene Polymorphisms With the Risk of Hepatitis B Virus-related Liver Diseases in a Guangxi Population: A Case-control Study.
Association of Paraoxonase-1(Q192R and L55M) Gene Polymorphisms and Activity with Colorectal Cancer and Effect of Surgical Intervention.
Association of PON1-L55M Genetic Variation and Breast Cancer Risk: A Case-Control Trial.
Barnidipine compared to lercanidipine in addition to losartan on endothelial damage and oxidative stress parameters in patients with hypertension and type 2 diabetes mellitus.
Biochemical effects, hypolipidemic and anti-inflammatory activities of Artemisia vulgaris extract in hypercholesterolemic rats.
Common genetic variants in the myeloperoxidase and paraoxonase genes and the related cancer risk: a review.
Complex Coronary Instent Chronic Total Occlusion Lesions: Oxidative Stress, Inflammation, and Coronary Stent Lengths.
Concentric vs. eccentric remodelling in heart failure with reduced ejection fraction: clinical characteristics, pathophysiology and response to treatment.
Coronary artery disease risk factors in patients with schizophrenia: effects of short term antipsychotic treatment.
Crosstalk Between Adipokines and Paraoxonase 1: A New Potential Axis Linking Oxidative Stress and Inflammation.
Cytokines, paraoxonase-1, periostin and non-invasive liver fibrosis scores in patients with non-alcoholic fatty liver disease and persistently elevated aminotransferases: A pilot study.
Decreased HDL-dependent paraoxonase and arylesterase enzyme activity may indicate a worse prognosis in multiple myeloma.
Differential effects of paraoxonase 1 (PON1) polymorphisms on cancer risk: evidence from 25 published studies.
Do CO2 and oxidative stress induce cancer?: a brief study about the evaluation of PON 1, CAT, CA and XO enzyme levels on head and neck cancer patients.
Effect of dapagliflozin and/or L-arginine on solid tumor model in mice: The interaction between nitric oxide, transforming growth factor-beta 1, autophagy, and apoptosis.
Effects of improved fat meat products consumption on emergent cardiovascular disease markers of male volunteers at cardiovascular risk.
Efficacy of oral rosuvastatin intervention on HDL and its associated proteins in men with type 2 diabetes mellitus.
Endothelial dysfunction and atherosclerosis in rheumatoid arthritis: a multiparametric analysis using imaging techniques and laboratory markers of inflammation and autoimmunity.
Epigenetic patterns of two gene promoters (TNF-? and PON) in stroke considering obesity condition and dietary intake.
Evaluation of the prognostic value of paraoxonase 1 in the recurrence and metastasis of hepatocellular carcinoma and establishment of a liver-specific predictive model of survival.
Exogenous supplement of N-acetylneuraminic acid ameliorates atherosclerosis in apolipoprotein E-deficient mice.
Expression and Intracellular Localization of Paraoxonase 2 in Different Types of Malignancies.
Gene expression signature of primary imatinib-resistant chronic myeloid leukemia patients.
Genetic polymorphism of paraoxonase 1 (PON1) and susceptibility to Parkinson's disease.
Hesperidin attenuates altered redox homeostasis in an experimental hyperlipidaemic model of rat.
Histological and biochemical investigation of the renoprotective effects of metformin in diabetic and prostate cancer model.
Human paraoxonase-1 gene expression by HepG2 cells is downregulated by interleukin-1beta and tumor necrosis factor-alpha, but is upregulated by interleukin-6.
Increased inflammatory markers with altered antioxidant status persist after clinical recovery from severe sepsis: a correlation with low HDL cholesterol and albumin.
Increased Levels of Plasma Tumor Necrosis Factor-? Mediate Schizophrenia Symptom Dimensions and Neurocognitive Impairments and Are Inversely Associated with Natural IgM Directed to Malondialdehyde and Paraoxonase 1 Activity.
Indolyl-chalcone derivatives induce hepatocellular carcinoma cells apoptosis through oxidative stress related mitochondrial pathway in vitro and in vivo.
Inflammation and Oxidative Stress in Deficit Schizophrenia.
Influence of heredity on human sensitivity to environmental chemicals.
Investigating paraoxonase-1 gene Q192R and L55M polymorphism in patients with renal cell cancer.
Investigation of anti-inflammatory effects of bee venom in experimentally induced adjuvant arthritis.
Is there a relation between genetic susceptibility with cancer? A study about paraoxanase (PON1) enzyme activity in breast cancer cases.
Liver X Receptor (LXR)-regulated Genes of Cholesterol Trafficking and Breast Cancer Severity.
Molecular and biochemical evidence on the protective effects of embelin and carnosic acid in isoproterenol-induced acute myocardial injury in rats.
N-(3-oxo-acyl) homoserine lactone inhibits tumor growth independent of Bcl-2 proteins.
Neuroprotective effects of bee venom acupuncture therapy against rotenone-induced oxidative stress and apoptosis.
New paraoxonase 1 polymorphism I102V and the risk of prostate cancer in Finnish men.
p-Cymene Modulate Oxidative Stress and Inflammation in Murine Macrophages: Potential Implication in atherosclerosis.
Paraoxonase 1 (PON1) polymorphisms and prostate cancer in the CPS-II Nutrition Cohort.
Paraoxonase 1 (PON1) Q192R Gene Polymorphism and Cancer Risk: A Meta-Analysis Based on 30 Publications.
Paraoxonase 1 (PON1) status in gastroesophageal malignancies and associated paraneoplastic syndromes - connection with inflammation.
Paraoxonase 2 overexpression inhibits tumor development in a mouse model of ovarian cancer.
Paraoxonase 2 Serves a Proapopotic Function in Mouse and Human Cells in Response to the Pseudomonas aeruginosa Quorum-sensing Molecule N-(3-Oxododecanoyl)-homoserine Lactone.
Paraoxonase-1 (PON1) induces metastatic potential and apoptosis escape via its antioxidative function in lung cancer cells.
Paraoxonase-1 (PON1) Status in Pancreatic Cancer: Relation to Clinical Parameters.
Paraoxonase-1 activity in patients with cancer: A systematic review and meta-analysis.
Persistence of an atherogenic lipid profile after treatment of acute infection with Brucella.
Persistent organic pollutants distribution in lipoprotein fractions in relation to cardiovascular disease and cancer.
Pharmacological interactions of paraoxonase 1 (PON1): A HDL-bound antiatherogenic enzyme.
Plasminogen Activator Inhibitor-1 Level Correlates with Lipoprotein Subfractions in Obese Nondiabetic Subjects.
Pro-inflammatory Mediators and Oxidative Stress: Therapeutic Markers for Recurrent Angina Pectoris after Coronary Artery Stenting in Elderly Patients.
Regulatory effects of dioxin-like and non-dioxin-like PCBs and other AhR ligands on the antioxidant enzymes paraoxonase 1/2/3.
Relationship between the paraoxonase 1 (PON1) M55L and Q192R polymorphisms and lymphohaematopoietic cancers in a Greek agricultural population.
Relationship of classical and non-classical risk factors with genetic variants relevant to coronary heart disease.
Serum arylesterase and paraoxonase activities in patients with ovarian tumors.
Serum paraoxonase 1 activity and protein N-homocysteinylation in primary human endometrial cancer.
Serum paraoxonase and arylesterase activities in patients with epithelial ovarian cancer.
Serum Paraoxonase-1 Concentration as a Potential Predictor of Urinary Bladder Cancer Recurrence. A Five Year Follow-Up Study.
Serum tumor necrosis factor-?, interleukin-6, monocyte chemotactic protein-1 and paraoxonase-1 profiles in women with endometriosis, PCOS, or unexplained infertility.
Single nucleotide polymorphisms in obesity-related genes and all-cause and cause-specific mortality: a prospective cohort study.
The investigation of the relationships of demodex density with inflammatory response and oxidative stress in rosacea.
The Role of Oxidative Stress and Inflammatory Mediators in Benign Paroxysmal Positional Vertigo.
The role of paraoxonase in cancer.
Therapeutic effect of simvastatin on DMBA-induced breast cancer in mice.
Transcriptomic characterization reveals prognostic molecular signatures of sorafenib resistance in hepatocellular carcinoma.
Vascular reactivity and biomarkers of endothelial function in healthy subjects exposed to acute hypobaric hypoxia.
[Studies on serum esterases in cancer. Cholinesterase and arylesterase activity]
Nephrotic Syndrome
Evaluation of paraoxonase activity in children with nephrotic syndrome.
Paraoxonase Activity and Lipid Profile in Paediatric Nephrotic Syndrome: A Cross-sectional Study.
Paraoxonase, total antioxidant response, and peroxide levels in children with steroid-sensitive nephrotic syndrome.
Serum paraoxonase activity and oxidative stress in patients with adult nephrotic syndrome.
Nervous System Diseases
Paraoxonase 1 in neurological disorders.
Pharmacological interactions of paraoxonase 1 (PON1): A HDL-bound antiatherogenic enzyme.
Neural Tube Defects
Amniotic fluid paraoxonase-1 activity, thyroid hormone concentration and oxidant status in neural tube defects.
Neurodegenerative Diseases
Decreased arylesterase activity of paraoxonase-1 (PON-1) might be a common denominator of neuroinflammatory and neurodegenerative diseases.
Paraoxonase 1 in neurological disorders.
Paraoxonase Role in Human Neurodegenerative Diseases.
Role of paraoxonase 1 (PON1) in organophosphate metabolism: Implications in neurodegenerative diseases.
Neurologic Manifestations
Activity of Paraoxonase/Arylesterase and Butyrylcholinesterase in Peripheral Blood of Gulf War Era Veterans With Neurologic Symptom Complexes or Post-Traumatic Stress Disorder.
Activity of Paraoxonase/Arylesterase and Butyrylcholinesterase in Peripheral Blood of Gulf War Era Veterans With Neurologic Symptom Complexes or Post-Traumatic Stress Disorder: Erratum.
Association of low PON1 type Q (type A) arylesterase activity with neurologic symptom complexes in Gulf War veterans.
Newcastle Disease
Ameliorative effect of synthetic ?-aminobutyric acid (GABA) on performance traits, antioxidant status and immune response in broiler exposed to cyclic heat stress.
Non-alcoholic Fatty Liver Disease
Açai (Euterpe oleracea Mart.) Upregulates Paraoxonase 1 Gene Expression and Activity with Concomitant Reduction of Hepatic Steatosis in High-Fat Diet-Fed Rats.
Association of carotid intima media thickness with atherogenic index of plasma, apo B/apo A-I ratio and paraoxonase activity in patients with non-alcoholic fatty liver disease.
Chemokine ligand 2 and paraoxonase-1 in non-alcoholic fatty liver disease: The search for alternative causative factors.
Cytokines, paraoxonase-1, periostin and non-invasive liver fibrosis scores in patients with non-alcoholic fatty liver disease and persistently elevated aminotransferases: A pilot study.
Fatty Liver Is Associated with Recurrent Bacterial Infections Independent of Metabolic Syndrome.
Involvement of xanthine oxidase and paraoxonase 1 in the process of oxidative stress in nonalcoholic fatty liver disease.
Paraoxonase 1 and Non-Alcoholic Fatty Liver Disease: A Meta-Analysis.
Paraoxonase activity and expression is modulated by therapeutics in experimental rat nonalcoholic Fatty liver disease.
Paraoxonase activity in sera of patients with non-alcoholic fatty liver disease.
Paraoxonase-1 activity, malondialdehyde and glutathione peroxidase in non-alcoholic fatty liver disease and the effect of atorvastatin.
Paraoxonase-1 Serum Concentration and PON1 Gene Polymorphisms: Relationship with Non-Alcoholic Fatty Liver Disease.
Pleiotropic Effects of Statins in the Light of Non-Alcoholic Fatty Liver Disease and Non-Alcoholic Steatohepatitis.
Protective effect of soy isoflavones and activity levels of plasma paraoxonase and arylesterase in the experimental nonalcoholic steatohepatitis model.
Serum paraoxonase 1 activity is paradoxically maintained in nonalcoholic fatty liver disease despite low HDL cholesterol.
Serum paraoxonase activity and oxidative stress and their relationship with obesity-related metabolic syndrome and non-alcoholic fatty liver disease in obese children and adolescents.
Serum paraoxonase and arylesterase activities in Iranian patients with nonalcoholic fatty liver disease.
Serum proteomic analysis of diet-induced steatohepatitis and metabolic syndrome in the Ossabaw miniature swine.
Soft drink consumption is associated with fatty liver disease independent of metabolic syndrome.
Suppressed hepatic bile acid signalling despite elevated production of primary and secondary bile acids in NAFLD.
Non-ST Elevated Myocardial Infarction
Association between paraoxonase 1 activity and severity of coronary artery disease in patients with acute coronary syndromes.
Nutrition Disorders
Effect of homocysteinylation on high density lipoprotein physico-chemical properties.
Obesity
African walnut (Tetracarpidium conophorum) modulates hepatic lipid accumulation in obesity via reciprocal actions on HMG-CoA reductase and paraoxonase.
Alteration of PON1 Activity in Adult and Childhood Obesity and Its Relation to Adipokine Levels.
Associations of PON1 and genetic ancestry with obesity in early childhood.
Changes in leptin, plasminogen activator factor and oxidative stress in morbidly obese patients following open and laparoscopic Swedish adjustable gastric banding.
Effect of yerba mate and green tea on paraoxonase and leptin levels in patients affected by overweight or obesity and dyslipidemia: a randomized clinical trial.
Genotypes of Common Polymorphisms in the PON1 Gene Associated with Paraoxonase Activity as Cardiovascular Risk Factor.
Letter to the editor: methodological approach to paraoxonase-1 activity in obesity complicated by obstructive sleep apnea.
Molecular characterization and expression analysis of the porcine paraoxonase 3 (PON3) gene.
Non-diabetic metabolic syndrome and obesity do not affect serum paraoxonase and arylesterase activities but do affect oxidative stress and inflammation.
Obesity and Breast Cancer: Molecular Interconnections and Potential Clinical Applications.
Overweight and Obesity in Polycystic Ovary Syndrome: Association with Inflammation, Oxidative Stress and Dyslipidemia.
Paraoxonase (PON)1 Q192R functional genotypes and PON1 Q192R genotype by smoking interactions are risk factors for the metabolic syndrome, but not overweight or obesity.
Paraoxonase 1: The Lectin-Like Oxidized LDL Receptor Type I and Oxidative Stress in the Blood of Men with Type II Obesity.
Paraoxonase activity in high-density lipoproteins: a comparison between healthy and obese females.
Paraoxonase-1 and adipokines: Potential links between obesity and atherosclerosis.
Pharmacological interactions of paraoxonase 1 (PON1): A HDL-bound antiatherogenic enzyme.
Q192R Polymorphism of Paraoxonase 1 Gene Associated with Insulin Resistance in Mexican Children.
Q192R polymorphism of the paraoxonase-1 gene as a risk factor for obesity in Portuguese women.
Relation of Paraoxonase 1 Activity with Biochemical Variables, Brachial Artery Intima-Media Thickness in Patients with Diabetes with or without Obesity.
Relationship between the paraoxonase (PON1) L55M and Q192R polymorphisms and obesity in a Mexican population: a pilot study.
Serum concentrations of trace elements and their relationships with paraoxonase-1 in morbidly obese women.
Serum paraoxonase-1 activity in children: the effects of obesity and insulin resistance.
Sex difference: an important issue to consider in epidemiological and clinical studies dealing with serum paraoxonase-1.
Obesity, Abdominal
Anti-atherogenic properties of high-density lipoproteins in psychiatric patients before and after two months of atypical anti-psychotic therapy.
Sex difference: an important issue to consider in epidemiological and clinical studies dealing with serum paraoxonase-1.
The Relation between Eating Habits and Abdominal Fat, Anthropometry, PON1 and IL-6 Levels in Patients with Multiple Sclerosis.
Osteoarthritis
Assessment of paraoxonase activities in patients with knee osteoarthritis.
Effects of Oral Hyaluronic Acid Administration in Dogs Following Tibial Tuberosity Advancement Surgery for Cranial Cruciate Ligament Injury.
Evaluation of selected parameters of lipid peroxidation and paraoxonase activity in blood of patients with joint osteoarthritis.
Expression of proteins in serum, synovial fluid, synovial membrane, and articular cartilage samples obtained from dogs with stifle joint osteoarthritis secondary to cranial cruciate ligament disease and dogs without stifle joint arthritis.
The concentration of thiobarbituric acid reactive substances (TBARS) and paraoxonase activity in blood of patients with osteoarthrosis after endoprosthesis implantation.
Osteoarthritis, Knee
Assessment of paraoxonase activities in patients with knee osteoarthritis.
Paraoxonase-1 activity and oxidative status in patients with knee osteoarthritis and their relationship with radiological and clinical parameters.
Osteomyelitis
The activity of paraoxonase and arylesterase in patients with osteomyelitis.
Osteonecrosis
Paraoxonase 1 gene polymorphisms in patients with osteonecrosis of the femoral head with and without cerebral white matter lesions.
The genetic association between PON1 polymorphisms and osteonecrosis of femoral head: A case-control study.
Osteoporosis
Association of serum paraoxonase concentration with serum lipid levels and bone mineral density measurements in early postmenopausal women.
Effects of paraoxonase 1 on the cytodifferentiation and mineralization of periodontal ligament cells.
Modulation of paraoxonase 1 (PON1) activity and protein N-homocysteinylation by bisphosphonates in rats.
Osteoporosis, Postmenopausal
HDL-Associated Paraoxonase 1 as a Bridge between Postmenopausal Osteoporosis and Cardiovascular Disease.
Osteosarcoma
Paraoxonase 1 192 and 55 polymorphisms in osteosarcoma.
Otitis Media
Serum paraoxonase and arylesterase activities in patients with chronic otitis media.
Otosclerosis
Oxidative stress in otosclerosis.
Ovarian Neoplasms
Paraoxonase 2 overexpression inhibits tumor development in a mouse model of ovarian cancer.
Serum paraoxonase and arylesterase activities in patients with epithelial ovarian cancer.
Overweight
Changes on the physiological lactonase activity of serum paraoxonase 1 by a diet intervention for weight loss in healthy overweight and obese women.
Effect of Quercetin on Paraoxonase 2 Levels in RAW264.7 Macrophages and in Human Monocytes--Role of Quercetin Metabolism.
Effect of yerba mate and green tea on paraoxonase and leptin levels in patients affected by overweight or obesity and dyslipidemia: a randomized clinical trial.
P074. Circulating adipokynes and Paraoxonase-1 activity in overweight Crohn's disease patients.
Paraoxonase (PON)-1 activity in overweight and obese children and adolescents: association with obesity-related inflammation and oxidative stress.
Paraoxonase (PON)1 Q192R functional genotypes and PON1 Q192R genotype by smoking interactions are risk factors for the metabolic syndrome, but not overweight or obesity.
Paraoxonase 1 Activity in Chylomicrons and VLDL: The Effect of Type 2 Diabetes and Meals Rich in Saturated Fat and Oleic Acid.
Paraoxonase, arylesterase and lactonase activities of paraoxonase-1 (PON1) in obese and severely obese women.
Paraoxonase-1 and myeloperoxidase correlate with vascular biomarkers in overweight patients with newly diagnosed untreated hyperlipidaemia.
Paraoxonase-1 arylesterase activity is an independent predictor of myeloperoxidase levels in overweight patients with or without cardiovascular complications.
Pancreatic Neoplasms
Paraoxonase 2 Facilitates Pancreatic Cancer Growth and Metastasis by Stimulating GLUT1-Mediated Glucose Transport.
Paraoxonase-1 (PON1) Status in Pancreatic Cancer: Relation to Clinical Parameters.
Pancreatitis
Association between antioxidants and mild acute pancreatitis.
Decreases in Paraoxonase-1 Activities Promote a Pro-inflammatory Effect of Lipids Peroxidation Products in Non-smoking and Smoking Patients with Acute Pancreatitis.
Serum paraoxonase (a high-density lipoprotein-associated lipophilic antioxidant) activity and lipid profile in experimental acute pancreatitis.
Pancreatitis, Chronic
Paraoxonase 1-192Q allele is a risk factor for idiopathic chronic pancreatitis.
Paraneoplastic Syndromes
Paraoxonase 1 (PON1) status in gastroesophageal malignancies and associated paraneoplastic syndromes - connection with inflammation.
Parkinson Disease
Association of a protective paraoxonase 1 (PON1) polymorphism in Parkinson's disease.
Association of paraoxonase 1 gene polymorphisms with risk of Parkinson's disease: a meta-analysis.
Association of Paraoxonse1 (PON1) Genotypes with the Activity of PON1 in Patients with Parkinson's Disease.
Functional paraoxonase 1 variants modify the risk of Parkinson's disease due to organophosphate exposure.
Further evidence for an association of the paraoxonase 1 (PON1) Met-54 allele with Parkinson's disease.
Genetic polymorphism of paraoxonase 1 (PON1) and susceptibility to Parkinson's disease.
Gln --> Arg 191 polymorphism of paraoxonase and Parkinson's disease.
Identification of brain proteins that interact with 2-methylnorharman. An analog of the parkinsonian-inducing toxin, MPP+.
No association between paraoxonase 1 (PON1) gene polymorphisms and susceptibility to Parkinson's disease in a Chinese population.
Novel Redox-Dependent Esterase Activity (EC 3.1.1.2) for DJ-1: Implications for Parkinson's Disease.
Paraoxonase 1 (PON1) gene polymorphisms and Parkinson's disease in a Finnish population.
Paraoxonase 1 Met--Leu 54 polymorphism is associated with Parkinson's disease.
Paraoxonase 1 polymorphisms L55M and Q192R were not risk factors for Parkinson's disease: a HuGE review and meta-analysis.
Paraoxonase 1 promoter and coding region polymorphisms in Parkinson's disease.
Paraoxonase 1, agricultural organophosphate exposure, and Parkinson disease.
Paraoxonase and arylesterase activity and total oxidative/anti-oxidative status in patients with idiopathic Parkinson's disease.
Paraoxonase polymorphisms, pesticide exposure and Parkinson's disease in a Caucasian population.
Paraoxonase-1 polymorphisms in Alzheimer's disease, Parkinson's disease, and AD-PD spectrum diseases.
Pesticides exposure and genetic polymorphism of paraoxonase in the susceptibility of Parkinson's disease.
Serological Profiles of Urate, Paraoxonase-1, Ferritin and Lipid in Parkinson's Disease: Changes Linked to Disease Progression.
[Polymorphisms in the genes of cytochrome oxidase P450 2D6 (CYP2D6), paraoxonase 1 (PON1) and apolipoprotein E (APOE) as risk factors for Parkinson's disease]
Pediatric Obesity
Favorable effect of short-term lifestyle intervention on human paraoxonase-1 activity and adipokine levels in childhood obesity.
Human paraoxonase-1 activity in childhood obesity and its relation to leptin and adiponectin levels.
Impaired paraoxonase-1 status in obese children. Relationships with insulin resistance and metabolic syndrome.
Paraoxonase 1 activities and genetic variation in childhood obesity.
Periodontitis
Effects of paraoxonase 1 on the cytodifferentiation and mineralization of periodontal ligament cells.
Potential Association of Paraoxonase 1, Type 2 Diabetes Mellitus and Periodontitis.
Peripheral Arterial Disease
No influence of increased intake of orange and blackcurrant juices and dietary amounts of vitamin E on paraoxonase-1 activity in patients with peripheral arterial disease.
Paraoxonase-1 activity modulates endothelial function in patients with peripheral arterial disease.
Peripheral Nervous System Diseases
Serum paraoxonase activity, concentration, and phenotype distribution in diabetes mellitus and its relationship to serum lipids and lipoproteins.
Peritonitis
Role of paraoxonase-1 as a diagnostic marker for feline infectious peritonitis.
Serum biomarkers of oxidative stress in cats with feline infectious peritonitis.
Persian Gulf Syndrome
Low paraoxonase in Persian Gulf War Veterans self-reporting Gulf War Syndrome.
Placenta Accreta
Decreased oxidative stress may contribute to the disease process in placenta accreta
Pneumonia
Zootechnical and health performance of Holstein x Gir crossbred calves.
[Arylesterase activity and total serum esterolytic activity in infants with pneumonia]
Pneumoperitoneum
Total oxidant status, total antioxidant status, and paraoxonase and arylesterase activities during laparoscopic cholecystectomy.
Polycystic Ovary Syndrome
Assessment of paraoxonase 1, xanthine oxidase and glutathione peroxidase activities, nitric oxide and thiol levels in women with polycystic ovary syndrome.
Association of Paraoxonase 1 Gene Polymorphisms and Polycystic Ovarian Syndrome Susceptibility: A Systematic Review and Meta-Analysis.
Association of PON1 gene polymorphisms with polycystic ovarian syndrome risk: a meta-analysis of case-control studies.
Association of SOD2 A16V and PON2 S311C polymorphisms with polycystic ovary syndrome in Chinese women.
Cardiovascular evaluation and serum paraoxonase-1 levels in adolescents with polycystic ovary syndrome.
Evaluation of endothelial dysfunction, lipid metabolism in women with polycystic ovary syndrome: relationship of paraoxonase 1 activity, malondialdehyde levels, low-density lipoprotein subfractions, and endothelial dysfunction.
Evidence for association between paraoxonase 1 gene polymorphisms and polycystic ovarian syndrome (PCOS) in south-west Chinese women.
Lactonase activity and status of paraoxonase 1 in Chinese women with polycystic ovarian syndrome.
Paraoxonase levels in women with polycystic ovary syndrome.
Paraoxonase single nucleotide variants show associations with polycystic ovary syndrome: a meta-analysis.
Paraoxonase-1 is not affected in polycystic ovary syndrome without metabolic syndrome and insulin resistance, but oxidative stress is altered.
PON1 polymorphisms are associated with polycystic ovary syndrome susceptibility, related traits, and PON1 activity in Indian women with the syndrome.
PON1-108 TT and PON1-192 RR genotypes are more frequently encountered in Greek PCOS than non-PCOS women, and are associated with hyperandrogenemia.
Serum paraoxonase 1 activity, asymmetric dimethylarginine levels, and brachial artery flow-mediated dilatation in women with polycystic ovary syndrome.
The association between paraoxonase 1 gene polymorphisms and polycystic ovarian syndrome.
The platelet activating factor acetyl hydrolase, oxidized low-density lipoprotein, paraoxonase 1 and arylesterase levels in treated and untreated patients with polycystic ovary syndrome.
The PON1-108C/T polymorphism, and not the polycystic ovary syndrome, is an important determinant of reduced serum paraoxonase activity in premenopausal women.
The role of proprotein convertase subtilisin/kexin type-9 concentration and paraoxonase 1 activities in the blood of women with polycystic ovary syndrome.
[Combined analyses of paraoxonase-1 and IGF-2 polymorphism in polycystic ovary syndrome]
[The -108 C/T polymorphism in paraoxonase 1 gene in Chinese patients with polycystic ovary syndrome].
Polyneuropathies
Bovine chromaffin cell cultures as model to study organophosporus neurotoxicity.
The relevance of inhibitor-substrate interactions when measuring neuropathy target esterase inhibition.
Prader-Willi Syndrome
Altered inflammation, paraoxonase-1 activity and HDL physicochemical properties in obese humans with and without Prader-Willi syndrome.
Pre-Eclampsia
Association of L55M and Q192R Polymorphisms of Paraoxonase-1 Gene with Preeclampsia.
Association of Midgestational Paraoxonase 1 Activity with Pregnancies Complicated by Preeclampsia.
Association of paraoxonase 55 and 192 gene polymorphisms on serum homocysteine concentrations in preeclampsia.
Changes of serum paraoxonase (an HDL-cholesterol-associated lipophilic antioxidant) and arylesterase activities in severe preeclamptic women.
Circulating oxidized low-density lipoprotein and paraoxonase activity in preeclampsia.
High-density lipoproteins (HDL) composition and function in preeclampsia.
Oxidative stress markers in severe preeclampsia and preeclampsia-related perinatal morbidity - preliminary report.
Oxidizability of apolipoprotein B-containing lipoproteins and serum paraoxonase/arylesterase activities in preeclampsia.
Paraoxonase and arylesterase activities in patients with preeclampsia.
Paraoxonase gene polymorphism, serum lipid, and oxidized low-density lipoprotein in preeclampsia.
Placental ADAMTS-12 Levels in the Pathogenesis of Preeclampsia and Intrahepatic Cholestasis of Pregnancy.
Serum levels of lipids, lipoproteins and paraoxonase activity in pre-eclampsia.
Prediabetic State
Potential Association of Paraoxonase 1, Type 2 Diabetes Mellitus and Periodontitis.
Serum Paraoxonase-1 Levels are Significantly Decreased in the Presence of Insulin Resistance.
Small high-density lipoprotein (HDL) subclasses are increased with decreased activity of HDL-associated phospholipase A? in subjects with prediabetes.
Pregnancy Complications
Paraoxonase gene polymorphism and vitamin levels during pregnancy: Relationship with maternal oxidative stress and neonatal birthweights.
Premature Birth
Association of midgestation paraoxonase 1 activity and pregnancies complicated by preterm birth.
Evaluation of Maternal Serum 25-Hydroxyvitamin D, Paraoxonase 1 Levels, and Neutrophil-to-Lymphocyte Ratio in Spontaneous Preterm Birth.
Presbycusis
The relationship between metabolic presbycusis and serum paraoxonase/arylesterase activity.
prostaglandin-endoperoxide synthase deficiency
A novel anti-atherogenic role for COX-2--potential mechanism for the cardiovascular side effects of COX-2 inhibitors.
Prostatic Hyperplasia
Increased Antioxidant Quality Versus Lower Quantity of High Density Lipoprotein in Benign Prostatic Hyperplasia.
Lipid associated antioxidants: arylesterase and paraoxonase-1 in benign prostatic hyperplasia treatment-naïve patients.
Prostatic Neoplasms
A pilot study assessing the association between paraoxonase 1 gene polymorphism and prostate cancer.
An alternative pseudolikelihood method for multivariate random-effects meta-analysis.
Comparison of serum acetyl hydrolase (PAF-AH) and paraoxonase 1 (PON1) values between prostate cancer patients and a control group.
Enhanced HDL-cholesterol-associated anti-oxidant PON-1 activity in prostate cancer patients.
New paraoxonase 1 polymorphism I102V and the risk of prostate cancer in Finnish men.
Paraoxonase 1 (PON1) polymorphisms and prostate cancer in the CPS-II Nutrition Cohort.
Proteinuria
Association of the novel cardiovascular risk factors paraoxonase 1 and cystatin C in type 2 diabetes.
Clinical leishmaniosis in a captive Eurasian otter (Lutra lutra) in Spain: a case report.
Increased HDL Size and Enhanced Apo A-I Catabolic Rates Are Associated With Doxorubicin-Induced Proteinuria in New Zealand White Rabbits.
Lipid profile among girls with systemic lupus erythematosus.
Serum ferritin and paraoxonase-1 in canine leishmaniosis.
Serum paraoxonase activity and oxidative stress in patients with adult nephrotic syndrome.
[Cholinesterase, arylesterase and proteinuria. A clinical trial in glomerular and tubular proteinuria (author's transl)]
[Is there a relationship between cystatin C and inflammatory status, oxidative stress and other cardiovascular risk factors in non-diabetic patients with chronic kidney disease?]
Pseudomonas Infections
Expression of PPAR? and Paraoxonase 2 Correlated with Pseudomonas aeruginosa Infection in Cystic Fibrosis.
Identification and analysis of the salt tolerant property of AHL lactonase (AiiATSAWB ) of Bacillus species.
Psoriasis
Antipsoriatic treatment extends beyond the skin: recovering of high-density lipoprotein function.
Association of paraoxonase 1 (PON1) L55M and PON1 Q192R gene polymorphisms and risk of psoriasis.
Biological anti-psoriatic therapy profoundly affects high-density lipoprotein function.
Correlation between Lp(a) and lipid peroxidation in psoriasis: role of the enzyme paraoxonase-1.
Effect of the systemic use of methotrexate on the oxidative stress and paraoxonase enzyme in psoriasis patients.
HDL associated paraoxonase-1 activity correlates with systemic inflammation, disease activity and cardiovascular risk factors in psoriatic disease.
Paraoxonase (PON1) 55 polymorphism, lipid profiles and psoriasis.
Paraoxonase-1 and other factors related to oxidative stress in psoriasis.
Paraoxonases and psoriasis: negative imbalance of anti--oxidant endogenous mechanisms.
Plasma oxidation status and antioxidant capacity in psoriatic children.
Psoriasis decreases the anti-oxidation and anti-inflammation properties of high-density lipoprotein.
Serum lipid profile paraoxonase and arylesterase activities in psoriasis.
Serum paraoxonase-1 activities and oxidative status in patients with plaque-type psoriasis with/without metabolic syndrome.
The relationship between oxidative stress, smoking and the clinical severity of psoriasis.
Pulmonary Disease, Chronic Obstructive
Arginines Plasma Concentration and Oxidative Stress in Mild to Moderate COPD.
Authors' Reply: Evaluation of Paraoxonase 1 Activity in Chronic Obstructive Pulmonary Disease.
Evaluation of Paraoxonase-1 Activity in Chronic Obstructive Pulmonary Disease.
Evaluation of serum paraoxonase and arylesterase activities in subjects with asthma and chronic obstructive lung disease.
Identification of Prognostic Value of Rs3735590 Polymorphism in 3'-Untranslated Region (3'-UTR) of Paraoxonase 1 (PON-1) in Chronic Obstructive Pulmonary Disease Patients who Received Coronary Artery Bypass Grafting (CABG).
Paraoxonase 1 activity in patients with chronic obstructive pulmonary disease.
Paraoxonase Activity and Phenotype Distribution in Patients with Chronic Obstructive Pulmonary Disease.
Paraoxonase-1 gene in patients with chronic obstructive pulmonary disease investigation Q192R and L55M polymorphisms.
Paraoxonase-1 is associated with corneal endothelial cell alterations in patients with chronic obstructive pulmonary disease.
Plasma protein thiols: an early marker of oxidative stress in asthma and chronic obstructive pulmonary disease.
PON1 gene polymorphisms in patients with chronic obstructive pulmonary disease.
Trace elements and oxidative stress in chronic obstructive pulmonary disease.
Pulmonary Embolism
The evaluation of two genetic polymorphisms of paraoxonase 1 in patients with pulmonary embolism.
Purpura
Effect of paraoxonase 1 gene polymorphisms on clinical course of Henoch-Schönlein purpura.
Pyometra
The plasma proteome and the acute phase protein response in canine pyometra.
Rectal Neoplasms
Identification of potential metabolic biomarkers of rectal cancer and of the effect of neoadjuvant radiochemotherapy.
Reflex, Abnormal
Prenatal organophosphate metabolite and organochlorine levels and performance on the Brazelton Neonatal Behavioral Assessment Scale in a multiethnic pregnancy cohort.
Renal Insufficiency
Activation of paraoxonase 1 after hemodialysis is associated with HDL remodeling and its increase in the HDL2 fraction and VLDL.
Decrease of serum paraoxonase activity in chronic renal failure.
Decreased paraoxonase 1 (PON1) lactonase activity in hemodialyzed and renal transplanted patients. A novel cardiovascular biomarker in end-stage renal disease.
Effect of continuous renal-replacement therapy on paraoxonase-1-related variables in patients with acute renal failure caused by septic shock.
Paraoxonase (PON1) Gene Polymorphisms in Fabry Disease: Correlation with Renal Disease.
The serum paraoxonase activity in patients with chronic renal failure and hyperlipidemia.
Renal Insufficiency, Chronic
Administration of exogenous erythropoietin beta affects lipid peroxidation and serum paraoxonase-1 activity and concentration in predialysis patients with chronic renal disease and anaemia.
Arylesterase activity but not PCSK9 levels is associated with chronic kidney disease in type 2 diabetes.
Association of lipid profile with serum PON1 concentration in patients with chronic kidney disease.
Comparison of serum paraoxonase and arylesterase activities between iron deficiency anemia patients and chronic kidney disease patients with anemia.
Diminished antioxidant activity of high-density lipoprotein-associated proteins in chronic kidney disease.
Discordance in human paraoxonase-1 gene between phenotypes and genotypes in chronic kidney disease.
Effect of nutritional status on human paraoxonase-1 activity in patients with chronic kidney disease.
Effect of oxidative stress on antioxidant enzyme activities, homocysteine and lipoproteins in chronic kidney disease.
Enhanced Angiotensin II type 1 receptor expression in leukocytes of patients with chronic kidney disease.
Genetic polymorphisms of paraoxonase-1 are associated with chronic kidney disease in Japanese women.
Hyperhomocysteinemia, paraoxonase concentration and cardiovascular complications in Tunisian patients with nondiabetic renal disease.
Paraoxonase enzyme activity and dyslipidemia in chronic kidney disease patients.
Serum Endocan Levels are Associated With Paraoxonase 1 Concentration in Patients With Chronic Kidney Disease.
Serum Paraoxonase Levels are Correlated with Impaired Aortic Functions in Patients with Chronic Kidney Disease.
Reperfusion Injury
Paraoxonase 2 protects against acute myocardial ischemia-reperfusion injury by modulating mitochondrial function and oxidative stress via the PI3K/Akt/GSK-3? RISK pathway.
Retinal Vein Occlusion
Molecular variant of the human paraoxonase/arylesterase gene is associated with central retinal vein occlusion in the Japanese population.
Protective effect of paraoxonase 1 gene variant L55M in retinal vein occlusion.
Rheumatic Diseases
Relationship of paraoxonase-1, malondialdehyde and mean platelet volume with markers of atherosclerosis in familial Mediterranean fever: an observational study.
Rhinitis, Allergic
Plasma paraoxonase activity and oxidative stress and their relationship to disease severity in children with allergic rhinitis.
Rosacea
Decreased serum paraoxonase and arylesterase activities in patients with rosacea.
Sarcoidosis
Association of serum amyloid A and oxidative stress with paraoxonase 1 in sarcoidosis patients.
Levels of paraoxonase, an index of antioxidant defense, in patients with active sarcoidosis.
Schistosomiasis mansoni
Schistosoma mansoni: Effect of dietary zinc supplement on egg granuloma in Swiss mice treated with praziqantel.
Scleroderma, Systemic
Plasma paraoxonase activity in patients with systemic sclerosis.
Seizures
Capsaicin Exerts Anti-convulsant and Neuroprotective Effects in Pentylenetetrazole-Induced Seizures.
Sepsis
Arylesterase Activity of HDL Associated Paraoxonase as a Potential Prognostic Marker in Patients With Sepsis and Septic Shock-A Prospective Pilot Study.
Cardiovascular Insufficiency, Abdominal Sepsis, and Patients' Age Are Associated with Decreased Paraoxonase-1 (PON1) Activity in Critically Ill Patients with Multiple Organ Dysfunction Syndrome (MODS).
Comparison of Protein Carbonyl (PCO), Paraoxonase-1 (PON1) and C-Reactive Protein (CRP) as Diagnostic and Prognostic Markers of Septic Inflammation in Dogs.
Decreased paraoxonase activity in critically ill patients with sepsis.
Early Elevation of Cell-free DNA After Acute Mesenteric Ischemia in Rats.
Effect of continuous renal-replacement therapy on paraoxonase-1-related variables in patients with acute renal failure caused by septic shock.
Effects of paraoxonase, arylesterase, ceruloplasmin, catalase, and myeloperoxidase activities on prognosis in pediatric patients with sepsis.
HDL Cholesterol Efflux is Impaired in Older Patients with Early Sepsis: A Subanalysis of a Prospective Pilot Study.
Identification of Protein Carbonyls (PCOs) in Canine Serum by Western Blot Technique and Preliminary Evaluation of PCO Concentration in Dogs With Systemic Inflammation.
Low paraoxonase 1 activity predicts mortality in surgical patients with sepsis.
Monocyte chemoattractant protein-1 and paraoxonase-1 and 3 levels in patients with sepsis treated in an intensive care unit: a preliminary report.
Paraoxonase 1 Activity and Survival in Sepsis Patients.
Prognostic value of serum paraoxonase and arylesterase activity in patients with sepsis.
Shock, Septic
Effect of continuous renal-replacement therapy on paraoxonase-1-related variables in patients with acute renal failure caused by septic shock.
Silicosis
[Serum myeloperoxidase activity and serum paraoxonase-1 activity in patients with silicosis and observation subjects and their clinical significance].
Sleep Apnea Syndromes
Oxidized-LDL and Paraoxonase-1 as biomarkers of Coronary Artery Disease in Patients with Sleep-Disordered Breathing.
Sleep Apnea, Obstructive
Letter to the editor: methodological approach to paraoxonase-1 activity in obesity complicated by obstructive sleep apnea.
Paraoxonase 1 Gene L55M Polymorphism and Paraoxonase 1 Activity in Obstructive Sleep Apnea Patients.
Reduced paraoxonase 1/arylesterase activity and its post-therapeutic increase in obstructive sleep apnea syndrome: a preliminary study.
Serum paraoxonase, arylesterase activity and oxidative status in patients with obstructive sleep apnea syndrome (OSAS).
Sleep Initiation and Maintenance Disorders
Serum paraoxonase, arylesterase activities and oxidative status in patients with insomnia.
Spasm
First survey of the three gene polymorphisms (PON1 Q192R, eNOS E298D and eNOS C-786T) potentially associated with coronary artery spasm in African populations and comparison with worldwide data.
Ischemic heart disease as deficiency disease.
Paraoxonase gene Gln192Arg (Q192R) polymorphism is associated with coronary artery spasm.
Variant angina and coronary artery spasm: the clinical spectrum, pathophysiology, and management.
Specific Language Disorder
Reevaluation of Serum Arylesterase Activity in Neurodevelopmental Disorders.
Spinal Cord Injuries
Effects of prostaglandin E1, melatonin, and oxytetracycline on lipid peroxidation, antioxidant defense system, paraoxonase (PON1) activities, and homocysteine levels in an animal model of spinal cord injury.
Medroxyprogesterone acetate, enoxaparin and pentoxyfylline cause alterations in lipid peroxidation, paraoxonase (PON1) activities and homocysteine levels in the acute oxidative stress in an experimental model of spinal cord injury.
Spinal Dysraphism
Paraoxonase 1 polymorphisms and haplotypes and the risk for having offspring affected with spina bifida in Southeast Mexico.
Spondylitis, Ankylosing
Carotid intima-media thickness and paraoxonase activity in patients with ankylosing spondylitis.
Correlation of PON1 polymorphisms with ankylosing spondylitis susceptibility: A case-control study in Chinese Han population.
Evaluation of paraoxonase and arylesterase activities in Egyptian patients with ankylosing spondylitis.
Evaluation of serum paraoxonase and arylesterase activities in ankylosing spondylitis patients.
ST Elevation Myocardial Infarction
Association between paraoxonase 1 activity and severity of coronary artery disease in patients with acute coronary syndromes.
Oxidative Stress and Paraoxonase 1 Activity Predict Contrast-Induced Nephropathy in Patients With ST-Segment Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention.
Paraoxonase-1 activity and oxidative stress in patients with anterior ST elevation myocardial infarction undergoing primary percutaneous coronary intervention with and without no-reflow.
Status Asthmaticus
Airborne particulate matter PM2.5 from Mexico City affects the generation of reactive oxygen species by blood neutrophils from asthmatics: an in vitro approach.
Status Epilepticus
Capsaicin Exerts Anti-convulsant and Neuroprotective Effects in Pentylenetetrazole-Induced Seizures.
Stomach Neoplasms
Association between paraoxonase-1 gene Q192R and L55M polymorphisms and risk of gastric cancer: A case-control study from Iran.
The clinical and prognostic significance of paraoxonase-2 in gastric cancer patients: immunohistochemical analysis.
The predictive role of Paraoxonase 1 (PON1) activity on survival in patients with metastatic and nonmetastatic gastric cancer.
Stomatitis, Aphthous
Serum prolidase and oxidative stress levels in patients with recurrent aphthous stomatitis: a prospective, controlled study.
Total serum oxidant/antioxidant status and arylesterase activity in recurrent aphthous stomatitis.
Stroke
A functional polymorphism of PON1 interferes with microRNA binding to increase the risk of ischemic stroke and carotid atherosclerosis.
Analysis of paraoxonase 1 (PON1) genetic polymorphisms and activities as risk factors for ischemic stroke in Turkish population.
Apolipoprotein A-I and Paraoxonase-1 Are Potential Blood Biomarkers for Ischemic Stroke Diagnosis.
Association between paraoxonase gene and stroke in the Han Chinese population.
Atherosclerosis and arteriosclerosis parameters in stroke patients associate with paraoxonase polymorphism and esterase activities.
Epigenetic patterns of two gene promoters (TNF-? and PON) in stroke considering obesity condition and dietary intake.
Evaluation of the paraoxonases as candidate genes for stroke: Gln192Arg polymorphism in the paraoxonase 1 gene is associated with increased risk of stroke.
Lack of association between the paraoxonase 1 Q/R192 single nucleotide polymorphism and stroke in a Chinese cohort.
Lipid peroxidation in stroke patients.
Meta-analysis of genetic studies from journals published in China of ischemic stroke in the Han Chinese population.
MRI cerebral white matter lesions and paraoxonase PON1 polymorphisms : three-year follow-up of the austrian stroke prevention study.
Paraoxonase 1 (PON1) and stroke; the dilemma of genetic variation.
Paraoxonase 1 gene Q192R polymorphism affects stroke and myocardial infarction risk.
Paraoxonase 1 in neurological disorders.
Paraoxonase 2 gene C311S polymorphism is associated with a risk of large vessel disease stroke in a Polish population.
Paraoxonase gene polymorphisms and haplotype analysis in a stroke population.
Paraoxonase gene polymorphisms and stroke severity.
Paraoxonase PON1 polymorphism leu-Met54 is associated with carotid atherosclerosis: results of the Austrian Stroke Prevention Study.
Paraoxonase-1 polymorphisms and cerebral ischemic stroke: a pilot study in mexican patients.
Paraoxonase-1 Q192R polymorphism is not associated with clopidogrel response in Chinese stroke patients.
PON1 55/192 polymorphism, oxidative stress, type, prognosis and severity of stroke.
Relationship between Paraoxonase 1 (PON1) gene polymorphisms and susceptibility of stroke: a meta-analysis.
Study of the relationship between gene polymorphisms of paraoxonase 2 and stroke in a Chinese population.
Systemic inflammation, endothelial dysfunction, dietary fatty acids and micronutrients as risk factors for stroke: a selective review.
The paraoxonase gene polymorphism in stroke patients and lipid profile.
[Relationship between single nucleotide polymorphisms of paraoxonase 2 and stroke]
[The effect of cigarette smoking on serum activities of paraoxonase and arylesterase in stroke patients]
Stroke, Lacunar
Serum paraoxonase and arylesterase activities in patients with lacunar infarction: a case control study.
Systemic Vasculitis
PON1, a new biomarker of cardiovascular disease, is low in patients with systemic vasculitis.
Takayasu Arteritis
Altered flow-mediated vasodilatation, low paraoxonase-1 activity, and abnormal high-density lipoprotein subclass distribution in Takayasu's arteritis.
Homocysteine levels in takayasu arteritis -- a risk factor for arterial ischemic events.
Teratozoospermia
Oxidative stress and phenotype frequencies of paraoxonase-1 in teratozoospermia.
Thalassemia
Serum Paraoxonase Activity and Malondialdehyde Serum Levels Remain Unaffected in Response to Hydroxyurea Therapy in ?-Thalassemia Patients.
Thrombosis
Circulating Fibroblast Growth Factor-23 Level and Paraoxonase-1 Lactonase Activity in Chronic Hemodialysis Patients: Their Impact on the Incidence of Native AV Fistula Thrombosis.
Ischemic heart disease as deficiency disease.
No association of paraoxonase-1 Q192R genotypes with platelet response to clopidogrel and risk of stent thrombosis after coronary stenting.
Paraoxonase-1 is not a major determinant of stent thrombosis in a Taiwanese population.
Polymorphisms of the paraoxonase gene and risk of preterm delivery.
The association of the PON1 Q192R polymorphism with complications and outcomes of pregnancy: findings from the British Women's Heart and Health cohort study.
Thyroid Cancer, Papillary
Paraoxonase and arylesterase activities in patients with papillary thyroid cancer.
Thyroid Diseases
Paraoxonase and arylesterase levels in autoimmune thyroid diseases.
Thyroid Neoplasms
Association between thyroid function and lipid profiles, apolipoproteins, and high-density lipoprotein function.
Thyroiditis
Increased paraoxonase and arylesterase activity in thyroiditis patients compared to healthy individuals: PS137.
Tinnitus
Paraoxonase Activity and Oxidative Status in Patients with Tinnitus.
Trauma, Nervous System
Three patients with probable aerotoxic syndrome.
Trichinellosis
Effect of cyclosporin A on trichinosis. A histochemical study.
Tuberculosis
PON1 activity and total oxidant status in patients with active pulmonary tuberculosis.
Serum paraoxonase and arylesterase activities in patients with pulmonary tuberculosis.
Tuberculosis, Pulmonary
PON1 activity and total oxidant status in patients with active pulmonary tuberculosis.
Serum paraoxonase 1 activity and oxidative stress in pediatric patients with pulmonary tuberculosis.
Serum paraoxonase and arylesterase activities in patients with pulmonary tuberculosis.
Uremia
Paraoxonase activity and paraoxonase 1 gene polymorphism in patients with uremia.
PON-1 carbamylation is enhanced in HDL of uremia patients.
Serum paraoxonase activity in uremic predialysis and hemodialysis patients.
Urinary Bladder Neoplasms
Alterations of Antioxidant Enzymes and Biomarkers of Nitro-oxidative Stress in Tissues of Bladder Cancer.
Diminished arylesterase enzyme activity and total thiol levels in bladder cancer patients.
Paraoxonase and arylesterase activity in bladder cancer.
Serum Paraoxonase-1 Concentration as a Potential Predictor of Urinary Bladder Cancer Recurrence. A Five Year Follow-Up Study.
Urolithiasis
Serum paraoxonase-1 gene polymorphism and enzyme activity in patients with urolithiasis.
Vascular Diseases
Accelerated atherosclerosis in rheumatoid arthritis.
Effect of paraoxonase 1 polymorphisms on the response of lipids and lipoprotein-associated enzymes to treatment with fluvastatin.
High expressor paraoxonase PON1 gene promoter polymorphisms are associated with reduced risk of vascular disease in younger coronary patients.
Lipoprotein trafficking in vascular cells. Molecular Trojan horses and cellular saboteurs.
Paraoxonase (PON1) phenotype is a better predictor of vascular disease than is PON1(192) or PON1(55) genotype.
Paraoxonase activity, but not haplotype utilizing the linkage disequilibrium structure, predicts vascular disease.
Paraoxonase-1 (PON1) activity as a risk factor for atherosclerosis in chronic renal failure patients.
Paraoxonase-1 expression is up-regulated in Down syndrome fetal liver.
Paraoxonase/arylesterase ratio, PON1 192Q/R polymorphism and PON1 status are associated with increased risk of ischemic stroke.
Postprandial modulation of serum paraoxonase activity and concentration in diabetic and non-diabetic subjects.
Serum paraoxonase 1 (PON1) measurement: an update.
TagSNP analyses of the PON gene cluster: effects on PON1 activity, LDL oxidative susceptibility, and vascular disease.
The correlation of paraoxonase (PON1) activity with lipid and lipoprotein levels differs with vascular disease status.
The role of 'paraoxonase-1 activity' as an antioxidant in coronary artery diseases.
Vascular Malformations
GLYOXALASE I A111E, PARAOXONASE 1 Q192R AND L55M POLYMORPHISMS IN ITALIAN PATIENTS WITH SPORADIC CEREBRAL CAVERNOUS MALFORMATIONS: A PILOT STUDY.
Venous Thromboembolism
The Diagnostic Value of Oxidative/Antioxidative Balance Parameters in Venous Thromboembolism.
Virus Diseases
Genetic association of paraoxonase-1 polymorphisms and chronic hepatitis C virus infection.
Maternal chronic hepatitis B virus is implicated with low neonatal paraoxonase/arylesterase activities.
Serum paraoxonase-1 activity and concentration are influenced by human immunodeficiency virus infection.
Vitamin B 12 Deficiency
Paraoxonase and arylesterase activities in adults with vitamin B12 deficiency.
Paraoxonase and arylesterase activities in children with iron deficiency anemia and vitamin B12 deficiency anemia.
Vitiligo
Reduced serum paraoxonase-1 levels in vitiligo: further evidence of oxidative stress.
White Coat Hypertension
Oxidative stress in white coat hypertension; role of paraoxonase.