Reference on EC 3.1.1.1 - carboxylesterase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Mentlein, R.; Schumann, M.; Heymann, E.
Comparative chemical and immunological characterization of five lipolytic enzymes (carboxylesterases) from rat liver microsomes
Arch. Biochem. Biophys.
234
612-621
1984
Rattus norvegicus
Hojring, N.; Svensmark, O.
Carboxylesterases of human brain extract. Purification and properties of a butyrylesterase
Biochim. Biophys. Acta
481
500-514
1977
Homo sapiens
Torres, J.L.; Rush, R.S.; Main, A.R.
Physical and chemical characterization of a horse serum carboxylesterase
Arch. Biochem. Biophys.
267
271-279
1988
Equus caballus
Abouakil, N.; Rogalska, E.; Bonicel, J.; Lombardo, D.
Purification of pancreatic carboxylic-ester hydrolase by immunoaffinity and its application of the human bile-salt-stimulated lipase
Biochim. Biophys. Acta
961
299-308
1988
Canis lupus familiaris, Homo sapiens, Rattus norvegicus
Okada, Y.; Wakabayashi, K.
Purification and characterization of esterases D-1 and D-2 from human erythrocytes
Arch. Biochem. Biophys.
263
130-136
1988
Homo sapiens
Saboori, A.M.; Newcombe, D.S.
Human monocyte carboxylesterase. Purification and kinetics
J. Biol. Chem.
265
19792-19799
1990
Homo sapiens
Cain, K.; Reiner, E.; Williams, D.G.
The identification and characterization of two separate carboxylesterases in guinea-pig serum
Biochem. J.
215
91-99
1983
Cavia porcellus
Siddalinga Murthy, K.R.; Veerabhadrappa, P.S.
Purification, characterization and properties of carboxylesterase from the midgut of the silkworm, Bombyx mori L
Insect Biochem. Mol. Biol.
26
287-296
1996
Bombyx mori
-
Hojring, N.; Svensmark, O.
Molecular and catalytic properties of a butyrylesterase from human red cells and brain
Arch. Biochem. Biophys.
260
351-358
1988
Homo sapiens
De Simone, G.; Manco, G.; Galdiero, S.; Lombardi, A.; Rossi, M.; Pavone, V.
Crystallization and preliminary X-ray diffraction studies of the carboxylesterase EST2 from Alicyclobacillus acidocaldarius
Acta Crystallogr. Sect. D
55
1348-1349
1999
Alicyclobacillus acidocaldarius
Oakeshott, J.G.; Collet, C.; Phillis, R.W.; Nielsen, K.M.; Russell, R.J.; Chambers, G.K.; Ross, V.; Richmond, R.C.
Molecular cloning and characterization of esterase-6, a serine hydrolase of Drosophila
Proc. Natl. Acad. Sci. USA
84
3359-3363
1987
Drosophila melanogaster
Cui, W.; Winter, W.T.; Tannenbaum, S.W.; Nakas, J.P.
Purification and characterization of an intracellular carboxylesterase from Arthrobacter viscosus NRRL B-1973
Enzyme Microb. Technol.
24
200-208
1999
Rhizobium viscosum, Rhizobium viscosum NRRL B-1973
-
Tanaka, M.; Lio, T.; Tabata, T.
Purification and characterization of a carboxylesterase from rabbit liver lysosomes
J. Biochem.
101
619-624
1987
Oryctolagus cuniculus
Goullet, P.; Picard, B.; Laget, P.F.
Purification and properties of carboxylesterase B of Escherichia coli
Ann. Microbiol.
135A
375-387
1984
Escherichia coli, Escherichia coli HB17
Krell, H.W.; Sandermann, H.
Plant biochemistry of xenobiotics. Purification and properties of a wheat esterase hydrolyzing the plasticizer chemical, bis(2-ethylhexyl)phthalate
Eur. J. Biochem.
143
57-62
1984
Triticum aestivum
White, K.N.; Hope, D.B.
Partial purification and characterization of a microsomal carboxylesterase specific for salicylate esters from guinea-pig liver
Biochim. Biophys. Acta
785
138-147
1984
Cavia porcellus
Wang, C.S.; Kloer, H.U.
Kinetic properties of human pancreatic carboxylesterase
Biochim. Biophys. Acta
754
142-149
1983
Homo sapiens
Tsujita, T.; Okuda, H.
Human liver carboxylesterase. Properties and comparison with human serum carboxylesterase
J. Biochem.
94
793-797
1983
Homo sapiens
Oehm, H.C.; de Looze, S.; Ronai, A.; von Deimling, O.
Purification and characterization of esterase 6A, a trimeric esterase of the house mouse (Mus musculus)
Eur. J. Biochem.
129
157-163
1982
Mus musculus
Tsujita, T.; Okuda, H.; Yamasaki, N.
Purification and some properties of carboxylesterase of rat adipose tissue
Biochim. Biophys. Acta
715
181-188
1982
Rattus norvegicus
Heymann, E.; Mentlein, R.
Carboxylesterases-amidases
Methods Enzymol.
77
333-344
1981
Rattus norvegicus
Otto, J.; Ronai, A.; von Deimling, O.
Purification and characterization of esterase 1F, the albumin esterase of the house mouse (Mus musculus)
Eur. J. Biochem.
116
285-291
1981
Mus musculus
Miller, S.K.; Main, A.R.; Rush, R.S.
Purification and physical properties of oligomeric and monomeric carboxylesterases from rabbit liver
J. Biol. Chem.
255
7161-7167
1980
Oryctolagus cuniculus
Farb, D.; Jencks, W.P.
Different forms of pig liver esterase
Arch. Biochem. Biophys.
203
214-226
1980
Sus scrofa
Lexow, U.; Ronai, A.; von Deimling, O.
Purification and characterization of esterase 2B of the house mouse, Mus musculus
Eur. J. Biochem.
107
123-130
1980
Mus musculus
Kim, K.K.; Hwang, K.Y.; Jang, W.H.; Lee, H.; Yoo, O.J.; Choi, M.U.; Suh, S.W.
Crystallization and preliminary X-ray crystallographic analysis of carboxylesterase from Pseudomonas fluorescens
Arch. Biochem. Biophys.
302
417-419
1993
Pseudomonas fluorescens
Junge, W.; Heymann, E.
Characterization of the isoenzymes of pig-liver esterase. 2. Kinetic studies
Eur. J. Biochem.
95
519-525
1979
Sus scrofa
Hashinotsume, M.; Higashino, K.; Hada, T.; Yamamura, Y.
Purification and enzymatic properties of rat serum carboxylesterase
J. Biochem.
84
1325-1333
1978
Rattus norvegicus
Lombardo, D.; Guy, O.; Figarella, C.
Purification and characterization of a carboxyl ester hydrolase from human pancreatic juice
Biochim. Biophys. Acta
527
142-149
1978
Homo sapiens
Goeppinger, A.; Riebschlaeger, M.; Ronai, A.; von Deimling, O.
Esterase XXVII. Purification and characterization of esterase-9A of mouse kidney
Biochim. Biophys. Acta
525
74-86
1978
Mus musculus
Devonshire, A.L.
The properties of a carboxylesterase from the peach-potato aphid, Myzus persicae (Sulz.), and its role in conferring insecticide resistance
Biochem. J.
167
675-683
1977
Myzus persicae
Ikeda, Y.; Okamura, K.; Arima, T.; Fujii, S.
Purification and characterization of two types of esterase from rat liver microsomes
Biochim. Biophys. Acta
487
189-203
1977
Rattus norvegicus
Scott, K.; Hamilton, S.E.; Zerner, B.
Purification and properties of a carboxylesterase from the liver of tiger shark (Galeocerdo cuvier)
Can. J. Biochem.
54
453-461
1976
Galeocerdo cuvier
Riefler III, J.F.; Higerd, T.B.
Characterization of intracellular esterase A from Bacillus subtilis
Biochim. Biophys. Acta
429
191-197
1976
Bacillus subtilis, Bacillus subtilis SR22
Coates, P.M.; Edwards, Y.H.; Hopkinson, D.A.
Purification and properties of an esterase B4 from human liver
Eur. J. Biochem.
61
331-335
1976
Homo sapiens
Dudman, N.P.B.; Zerner, B.
Carboxylesterase from pig and ox liver
Methods Enzymol.
35B
190-208
1975
Bos taurus, Sus scrofa
-
Stoops, J.K.; Hamilton, S.E.; Zerner, B.
Carboxylesterases (EC 3.1.1). A comparison of some kinetic properties of horse, sheep, chicken, pig, and ox liver carboxylesterases
Can. J. Biochem.
53
565-573
1975
Bos taurus, Gallus gallus, Equus caballus, Ovis aries, Sus scrofa
Inkerman, P.A.; Scott, K.; Runnegar, M.T.C.; Hamilton, S.E.; Bennett, E.A.; Zerner, B.
Carboxylesterases (EC 3.1.1). Purification and titration of chicken, sheep, and horse liver carboxylesterases
Can. J. Biochem.
53
536-546
1975
Gallus gallus, Equus caballus, Ovis aries
Junge, W.; Heymann, E.; Krisch, K.; Hollandt, H.
Human liver carboxylesterase. Purification and molecular properties
Arch. Biochem. Biophys.
165
749-763
1974
Homo sapiens
Haugen, D.A.; Suttie, J.W.
Purification and properties of rat liver microsomal esterases
J. Biol. Chem.
249
2717-2722
1974
Rattus norvegicus
Arndt, R.; Heymann, E.; Junge, W.; Krisch, K.; Kollandt, H.
Purification and molecular properties of an unspecific carboxylesterase (E1) from rat-liver microsomes
Eur. J. Biochem.
36
120-128
1973
Rattus norvegicus
Arndt, R.; Krisch, K.
Catalytic properties of an unspecific carboxylesterase (E1) from rat-liver microsomes
Eur. J. Biochem.
36
129-134
1973
Rattus norvegicus
McGhee, J.D.
Purification and characterization of a carboxylesterase from the intestine of the nematode Caenorhabditis elegans
Biochemistry
26
4101-4107
1987
Caenorhabditis elegans
Mori, M.; Hosokawa, M.; Ogasawara, Y.; Tsukada, E.; Chiba, K.
cDNA cloning, characterization and stable expression of a novel human brain carboxylesterase
FEBS Lett.
458
17-22
1999
Homo sapiens (P23141), Homo sapiens
Einarsson, J.M.; Sigmundsson, K.; Fillippusson, H.
Purification and some properties of a carboxylesterase from ovine liver
Comp. Biochem. Physiol. B
114
41-48
1996
Ovis aries
Wood, A.N.P.; Fernandez-Lafuente, R.; Cowan, D.A.
Purification and partial characterization of a novel thermophilic carboxylesterase with high mesophilic specific activity
Enzyme Microb. Technol.
17
816-825
1995
Geobacillus stearothermophilus
Manco, G.; di Gennaro, S.; de Rosa, M.; Rossi, M.
Purification and characterization of a thermostable carboxylesterase from the thermoacidophilic eubacterium Bacillus acidocaldarius
Eur. J. Biochem.
221
965-972
1994
Alicyclobacillus acidocaldarius
Mukherjee, J.J.; Jay, F.T.; Choy, P.C.
Purification, characterization and modulation of a microsomal carboxylesterase in rat liver for the hydrolysis of acyl-CoA
Biochem. J.
295
81-86
1993
Rattus norvegicus
Scher, H.; Langmann, T.; Daig, R.; Becker, A.; Aslanidis, C.; Schmitz, G.
Molecular cloning and characterization of a novel putative carboxylesterase, present in human intestine and liver
Biochem. Biophys. Res. Commun.
233
117-120
1997
Homo sapiens
Luan, L.; Sugiyama, T.; Takai, S; Usami, Y.; Adachi, T.; Katagiri, Y.; Hirano, K.
Purification and characterization of pranlukast hydrolase from rat liver microsomes: the hydrolase is identical to carboxylesterase pI 6.2
Biol. Pharm. Bull.
20
71-75
1997
Rattus norvegicus
Kim, Y.S.; Lee, H.B.; Choi, K.D.; Park, S.; Yoo, O.J.
Cloning of Pseudomonas fluorescens carboxylesterase gene and characterization of its product expressed in Escherichia coli
Biosci. Biotechnol. Biochem.
58
111-116
1994
Pseudomonas fluorescens
Sugihara, A.; Shimada, Y.; Nagao, T.; Iizumi, T.; Nakamura, K.; Fukase, T.; Tominaga, Y.
Purification and characterization of a carboxylesterase from Pseudomonas sp. KWI-56
Biosci. Biotechnol. Biochem.
58
752-755
1994
Pseudomonas sp., Pseudomonas sp. KWI-56
Ketterman, A.J.; Jayawardena, K.G.I.; Hemingway, J.
Purification and characterization of a carboxylesterase involved in insecticide resistance from mosquito Culex quinquefasciatus
Biochem. J.
287
355-360
1992
Culex quinquefasciatus
Nishizawa, M.; Gomi, H.; Kishimoto, F.
Purification and some properties of carboxylesterase from Arthrobacter globiformis stereoselective hydrolysis of ethyl chrysanthemate
Biosci. Biotechnol. Biochem.
57
594-598
1993
Arthrobacter globiformis, Arthrobacter globiformis SC-69828
-
Miller, A.D.; Scott, D.F.; Chacko, T.L.; Maywell, D.M.; Schlager, J.J.; Lanclos, K.D.
Expression and partial purification of a recombinant secretory form of human liver carboxylesterase
Protein Expr. Purif.
17
16-25
1999
Homo sapiens (P23141), Homo sapiens
Kim, K.K.; Song, H.K.; Shin, D.H.; Hwang, K.Y.; Choe, S.; Yoo, O.J.; Suh, S.W.
Crystal structure of carboxylesterase from Pseudomonas fluorescens, an alpha/beta hydrolase with broad substrate specificity: Structure of carboxylesterase from Pseudomonas fluorescens, an alpha/beta hydrolase with broad substrate specificity
Structure
15
1571-1584
1997
Pseudomonas fluorescens
Ketterman, A.J.; Jayawardena, K.G.I.; Hemingway, J.
Purification and characterisation of a mosquito carboxylesterase involved in insecticide resistance
Biochem. Soc. Trans.
19
305S
1991
Culex quinquefasciatus
Liu, P.; Wang, Y.F.; Ewis, H.E.; Abdelal, A.; Lu, C.D.; Weber, I.T.
Crystallization and preliminary X-ray diffraction data for the carboxylesterase Est30 from Bacillus stearothermophilus
Acta Crystallogr. Sect. D
59
1472-1473
2003
Geobacillus stearothermophilus
Hennebelle, I.; Terret, C.; Chatelut, E.; Bugat, R.; Canal, P.; Guichard, S.
Characterization of CPT-11 converting carboxylesterase activity in colon tumor and normal tissues: comparison with p-nitro-phenylacetate converting carboxylesterase activity
Anticancer Drugs
11
465-470
2000
Homo sapiens
Kademi, A.; Ait-Abdelkader, N.; Fakhreddine, L.; Baratti, J.
Purification and characterization of a thermostable esterase from the moderate thermophile Bacillus circulans
Appl. Microbiol. Biotechnol.
54
173-179
2000
Niallia circulans
Reiter, B.; Glieder, A.; Talker, D.; Schwab, H.
Cloning and characterization of EstC from Burkholderia gladioli, a novel-type esterase related to plant enzymes
Appl. Microbiol. Biotechnol.
54
778-785
2000
Burkholderia gladioli (Q9LAB8), Burkholderia gladioli
Redinbo, M.R.; Bencharit, S.; Potter, P.M.
Human carboxylesterase 1: from drug metabolism to drug discovery
Biochem. Soc. Trans.
31
620-624
2003
Homo sapiens
Converti, A.; Del Borghi, A.; Gandolfi, R.; Lodi, A.; Molinari, F.; Palazzi, E.
Reactivity and stability of mycelium-bound carboxylesterase from Aspergillus oryzae
Biotechnol. Bioeng.
77
232-237
2002
Aspergillus oryzae
Sehgal, A.C.; Tompson, R.; Cavanagh, J.; Kelly, R.M.
Structural and catalytic response to temperature and cosolvents of carboxylesterase EST1 from the extremely thermoacidophilic archaeon Sulfolobus solfataricus P1
Biotechnol. Bioeng.
80
784-793
2002
Saccharolobus solfataricus, Saccharolobus solfataricus P1
Zhang, J.; Liu, J.; Zhou, J.; Ren, Y.; Dai, X.; Xiang, H.
Thermostable esterase from Thermoanaerobacter tengcongensis: high-level expression, purification and characterization
Biotechnol. Lett.
25
1463-1467
2003
Caldanaerobacter subterraneus subsp. tengcongensis
Humerickhouse, R.; Lohrbach, K.; Li, L.; Bosron, W.F.; Dolan, M.E.
Characterization of CPT-11 hydrolysis by human liver carboxylesterase isoforms hCE-1 and hCE-2
Cancer Res.
60
1189-1192
2000
Homo sapiens
Lange, S.; Musidlowska, A.; Schmidt-Dannert, C.; Schmitt, J.; Bornscheuer, U.T.
Cloning, functional expression, and characterization of recombinant pig liver esterase
ChemBioChem
2
576-582
2001
Sus scrofa, Sus scrofa PLE
Henke, E.; Bornscheuer, U.T.; Schmid, R.D.; Pleiss, J.
A molecular mechanism of enantiorecognition of tertiary alcohols by carboxylesterases
ChemBioChem
4
485-493
2003
Bacillus subtilis, Sus scrofa
Prim, N.; Pastor, F.I.; Diaz, P.
Cloning and characterization of a bacterial cell-bound type B carboxylesterase from Bacillus sp. BP-7
Curr. Microbiol.
42
237-240
2001
Bacillus sp. (in: Bacteria), Bacillus sp. (in: Bacteria) BP-7
Kim, H.E.; Park, K.R.
Purification and characterization of an esterase from Acinetobacter lwoffii I6C-1
Curr. Microbiol.
44
401-405
2002
Acinetobacter lwoffii, Acinetobacter lwoffii I6C-1
Sanghani, S.P.; Davis, W.I.; Dumaual, N.G.; Mahrenholz, A.; Bosron, W.F.
Identification of microsomal rat liver carboxylesterases and their activity with retinyl palmitate
Eur. J. Biochem.
269
4387-4398
2002
Rattus norvegicus (O35535), Rattus norvegicus (O70631), Rattus norvegicus (P16303), Rattus norvegicus (Q63108), Rattus norvegicus (Q64573), Rattus norvegicus (Q8K3R0)
Honda, K.; Kataoka, M.; Ono, H.; Sakamoto, K.; Kita, S.; Shimizu, S.
Purification and characterization of a novel esterase promising for the production of useful compounds from Microbacterium sp. 7-1W
FEMS Microbiol. Lett.
206
221-227
2002
Microbacterium sp., Microbacterium sp. 7-1W
Uchida, H.; Kurakata, Y.; Sawamura, H.; Inamura, N.; Kotani, T.; Uwajima, T.
Purification and properties of an esterase from Aspergillus nomius HS-1 degrading ethylene glycol dibenzoate
FEMS Microbiol. Lett.
223
123-127
2003
Aspergillus nomiae, Aspergillus nomiae HS-1
Valles, S.M.; Oi, F.M.; Strong, C.A.
Purification and characterization of trans-permethrin metabolizing microsomal esterases from workers of the eastern subterranean termite, Reticulitermes flavipes (Kollar)
Insect Biochem. Mol. Biol.
31
715-725
2001
Reticulitermes flavipes
Haubruge, E.; Amichot, M.; Cuany, A.; Berge, J.B.; Arnaud, L.
Purification and characterization of a carboxylesterase involved in malathion-specific resistance from Tribolium castaneum (Coleoptera: Tenebrionidae)
Insect Biochem. Mol. Biol.
32
1181-1190
2002
Tribolium castaneum
Nardi, M.; Fiez-Vandal, C.; Tailliez, P.; Monnet, V.
The EstA esterase is responsible for the main capacity of Lactococcus lactis to synthesize short chain fatty acid esters in vitro
J. Appl. Microbiol.
93
994-1002
2002
Lactococcus lactis (Q8KWI9), Lactococcus lactis
Manco, G.; Mandrich, L.; Rossi, M.
Residues at the active site of the esterase 2 from Alicyclobacillus acidocaldarius involved in substrate specificity and catalytic activity at high temperature
J. Biol. Chem.
276
37482-37490
2001
Alicyclobacillus acidocaldarius
Valkova, N.; Lepine, F.; Labrie, L.; Dupont, M.; Beaudet, R.
Purification and characterization of PrbA, a new esterase from Enterobacter cloacae hydrolyzing the esters of 4-hydroxybenzoic acid (parabens)
J. Biol. Chem.
278
12779-12785
2003
Enterobacter cloacae, Enterobacter cloacae EM
Sanishvili, R.; Yakunin, A.F.; Laskowski, R.A.; Skarina, T.; Evdokimova, E.; Doherty-Kirby, A.; Lajoie, G.A.; Thornton, J.M.; Arrowsmith, C.H.; Savchenko, A.; Joachimiak, A.; Edwards, A.M.
Integrating structure, bioinformatics, and enzymology to discover function. BioH, a new carboxylesterase from Escherichia coli
J. Biol. Chem.
278
26039-26045
2003
Escherichia coli, Escherichia coli (P13001)
De Simone, G.; Mandrich, L.; Menchise, V.; Giordano, V.; Febbraio, F.; Rossi, M.; Pedone, C.; Manco, G.
A Substrate-induced switch in the reaction mechanism of a thermophilic esterase: kinetic evidences and structural basis
J. Biol. Chem.
279
6815-6823
2004
Alicyclobacillus acidocaldarius
Sousa, H.A.; Afonso, C.A.M.; Crespo, J.G.
Kinetic study of the enantioselective hydrolysis of a meso-diester using pig liver Esterase
J. Chem. Technol. Biotechnol.
75
707-714
2000
Sus scrofa
-
Fenster, K.M.; Parkin, K.L.; Steele, J.L.
Intracellular esterase from Lactobacillus casei LILA: nucleotide sequencing, purification, and characterization
J. Dairy Sci.
86
1118-1129
2003
Lactobacillus delbrueckii subsp. lactis, Lacticaseibacillus casei (Q8KT44), Lacticaseibacillus casei, Lactobacillus delbrueckii subsp. lactis MG1363 EstA, Lacticaseibacillus casei LILA EstC (Q8KT44)
De Simone, G.; Menchise, V.; Manco, G.; Mandrich, L.; Sorrentino, N.; Lang, D.; Rossi, M.; Pedone, C.
The crystal structure of a hyper-thermophilic carboxylesterase from the archaeon Archaeoglobus fulgidus
J. Mol. Biol.
314
507-518
2001
Archaeoglobus fulgidus
Suoniemi, A.; Tynkkynen, S.
Cloning and characterization of an esterase from Propionibacterium freudenreichii ssp. shermanii
Lait
82
81-89
2002
Propionibacterium freudenreichii
-
Choi, G.S.; Kim, J.Y.; Kim, J.H.; Ryu, Y.W.; Kim, G.J.
Construction and characterization of a recombinant esterase with high activity and enantioselectivity to (S)-ketoprofen ethyl ester
Protein Expr. Purif.
29
85-93
2003
Pseudomonas fluorescens (Q8VU79), Pseudomonas fluorescens KCTC1767 (Q8VU79)
Suzuki, T.; Nakayama, T.; Choo, D.W.; Hirano, Y.; Kurihara, T.; Nishino, T.; Esaki, N.
Cloning, heterologous expression, renaturation, and characterization of a cold-adapted esterase with unique primary structure from a psychrotroph Pseudomonas sp. strain B11-1
Protein Expr. Purif.
30
171-178
2003
Pseudomonas sp. (Q8GR22), Pseudomonas sp., Pseudomonas sp. B11-1 (Q8GR22)
Kuznetsova, E.; Proudfoot, M.; Sanders, S.A.; Reinking, J.; Savchenko, A.; Arrowsmith, C.H.; Edwards, A.M.; Yakunin, A.F.
Enzyme genomics: Application of general enzymatic screens to discover new enzymes
FEMS Microbiol. Rev.
29
263-279
2005
Escherichia coli (P04335)
Pesaresi, A.; Devescovi, G.; Lamba, D.; Venturi, V.; Degrassi, G.
Isolation, characterization, and heterologous expression of a carboxylesterase of Pseudomonas aeruginosa PAO1
Curr. Microbiol.
50
102-109
2005
Pseudomonas aeruginosa, Pseudomonas aeruginosa PAO1
Wilhelm, S.; Tommassen, J.; Jaeger, K.E.
A novel lipolytic enzyme located in the outer membrane of Pseudomonas aeruginosa
J. Bacteriol.
181
6977-6986
1999
Pseudomonas aeruginosa (O33407), Pseudomonas aeruginosa
Chahinian, H.; Ali, Y.B.; Abousalham, A.; Petry, S.; Mandrich, L.; Manco, G.; Canaan, S.; Sarda, L.
Substrate specificity and kinetic properties of enzymes belonging to the hormone-sensitive lipase family: comparison with non-lipolytic and lipolytic carboxylesterases
Biochim. Biophys. Acta
1738
29-36
2005
Alicyclobacillus acidocaldarius, Archaeoglobus fulgidus, Homo sapiens
Linke, T.; Dawson, H.; Harrison, E.H.
Isolation and characterization of a microsomal acid retinyl ester hydrolase
J. Biol. Chem.
280
23287-23294
2005
Rattus norvegicus
Choi, Y.J.; Miguez, C.B.; Lee, B.H.
Characterization and heterologous gene expression of a novel esterase from Lactobacillus casei CL96
Appl. Environ. Microbiol.
70
3213-3221
2004
Lacticaseibacillus casei (Q840T2), Lacticaseibacillus casei, Lacticaseibacillus casei CL96 (Q840T2)
Wheelock, C.E.; Eder, K.J.; Werner, I.; Huang, H.; Jones, P.D.; Brammell, B.F.; Elskus, A.A.; Hammock, B.D.
Individual variability in esterase activity and CYP1A levels in Chinook salmon (Oncorhynchus tshawytscha) exposed to esfenvalerate and chlorpyrifos
Aquat. Toxicol.
74
172-192
2005
Oncorhynchus tshawytscha
Kuster, E.
Cholin- and carboxylesterase activities in developing zebrafish embryos (Danio rerio) and their potential use for insecticide hazard assessment
Aquat. Toxicol.
75
76-85
2005
Danio rerio
Nishi, K.; Huang, H.; Kamita, S.G.; Kim, I.H.; Morisseau, C.; Hammock, B.D.
Characterization of pyrethroid hydrolysis by the human liver carboxylesterases hCE-1 and hCE-2
Arch. Biochem. Biophys.
445
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Homo sapiens (P23141), Homo sapiens
Kulakova, L.; Galkin, A.; Nakayama, T.; Nishino, T.; Esaki, N.
Cold-active esterase from Psychrobacter sp. Ant300: gene cloning, characterization, and the effects of Gly->Pro substitution near the active site on its catalytic activity and stability
Biochim. Biophys. Acta
1696
59-65
2004
Psychrobacter sp., Psychrobacter sp. Ant300
Stocker, P.; Yousfi, M.; Djerridane, O.; Perrier, J.; Amziani, R.; El Boustani, S.; Moulin, A.
Effect of flavonoids from various Mediterranean plants on enzymatic activity of intestinal carboxylesterase
Biochimie
86
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2004
Rattus norvegicus, Sus scrofa
Mnisi, S.M.; Louw, M.E.; Theron, J.
Cloning and characterization of a carboxylesterase from Bacillus coagulans 81-11
Curr. Microbiol.
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Weizmannia coagulans, Weizmannia coagulans 81-11
Sanghani, S.P.; Quinney, S.K.; Fredenburg, T.B.; Davis, W.I.; Murry, D.J.; Bosron, W.F.
Hydrolysis of irinotecan and its oxidative metabolites, 7-ethyl-10-[4-N-(5-aminopentanoic acid)-1-piperidino] carbonyloxycamptothecin and 7-ethyl-10-[4-(1-piperidino)-1-amino]-carbonyloxycamptothecin, by human carboxylesterases CES1A1, CES2, and a newly expressed carboxylesterase isoenzyme, CES3
Drug Metab. Dispos.
32
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2004
Homo sapiens
Zhang, J.L.; Qiao, C.L.; Lan, W.S.
Detoxification of organophosphorus compounds by recombinant carboxylesterase from an insecticide-resistant mosquito and oxime-induced amplification of enzyme activity
Environ. Toxicol.
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2004
Culex sp.
Zhang, J.L.; Qiao, C.L.; Lan, W.S.
Purification and some characteristics of recombinant insecticide-resistant mosquito carboxylesterase B1 expressed in Escherichia coli
Enzyme Microb. Technol.
36
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2005
Culex sp.
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Vakhlu, J.; Johri, S.; Verma, V.; Koul, S.; Parshad, R.; Taneja, S.C.; Qazi, G.N.
Purification and properties of enantioselective ester hydrolase from a strain of Trichosporon species (DSMZ 11829)
Enzyme Microb. Technol.
37
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2005
Trichosporon sp.
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Canaan, S.; Maurin, D.; Chahinian, H.; Pouilly, B.; Durousseau, C.; Frassinetti, F.; Scappuccini-Calvo, L.; Cambillau, C.; Bourne, Y.
Expression and characterization of the protein Rv1399c from Mycobacterium tuberculosis. A novel carboxyl esterase structurally related to the HSL family
Eur. J. Biochem.
271
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2004
Mycobacterium tuberculosis
Ewis, H.E.; Abdelal, A.T.; Lu, C.D.
Molecular cloning and characterization of two thermostable carboxyl esterases from Geobacillus stearothermophilus
Gene
329
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2004
Geobacillus stearothermophilus
Heidari, R.; Devonshire, A.L.; Campbell, B.E.; Dorrian, S.J.; Oakeshott, J.G.; Russell, R.J.
Hydrolysis of pyrethroids by carboxylesterases from Lucilia cuprina and Drosophila melanogaster with active sites modified by in vitro mutagenesis
Insect Biochem. Mol. Biol.
35
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2005
Drosophila melanogaster, Lucilia cuprina
Wu, P.C.; Liu, Y.H.; Wang, Z.Y.; Zhang, X.Y.; Li, H.; Liang, W.Q.; Luo, N.; Hu, J.M.; Lu, J.Q.; Luan, T.G.; Cao, L.X.
Molecular cloning, purification, and biochemical characterization of a novel pyrethroid-hydrolyzing esterase from Klebsiella sp. strain ZD112
J. Agric. Food Chem.
54
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2006
Klebsiella sp. (Q52NW7), Klebsiella sp., Klebsiella sp. ZD112 (Q52NW7)
Maruyama, K.; Akita, K.; Naitou, C.; Yoshida, M.; Kitamura, T.
Purification and characterization of an esterase hydrolyzing monoalkyl phthalates from Micrococcus sp. YGJ1
J. Biochem.
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2005
Micrococcus sp., Micrococcus sp. YGJ1
Stok, J.E.; Huang, H.; Jones, P.D.; Wheelock, C.E.; Morisseau, C.; Hammock, B.D.
Identification, expression, and purification of a pyrethroid-hydrolyzing carboxylesterase from mouse liver microsomes
J. Biol. Chem.
279
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Mus musculus, Mus musculus (Q8BK48)
Ejima, K.; Liu, J.; Oshima, Y.; Hirooka, K.; Shimanuki, S.; Yokota, Y.; Hemmi, H.; Nakayama, T.; Nishino, T.
Molecular cloning and characterization of a thermostable carboxylesterase from an archaeon, Sulfolobus shibatae DSM5389: non-linear kinetic behavior of a hormone-sensitive lipase family enzyme
J. Biosci. Bioeng.
98
445-451
2004
Saccharolobus shibatae, Saccharolobus shibatae DSM 5389
Mandrich, L.; Merone, L.; Pezzullo, M.; Cipolla, L.; Nicotra, F.; Rossi, M.; Manco, G.
Role of the N terminus in enzyme activity, stability and specificity in thermophilic esterases belonging to the HSL family
J. Mol. Biol.
345
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2004
Alicyclobacillus acidocaldarius, Saccharolobus solfataricus, Saccharolobus solfataricus (Q97VU2), Saccharolobus solfataricus P2 (Q97VU2), Saccharolobus solfataricus P2
Droege, M.J.; Bos, R.; Boersma, Y.L.; Quax, W.J.
Comparison and functional characterization of three homologous intracellular carboxylesterases of Bacillus subtilis
J. Mol. Catal. B
32
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2005
Bacillus subtilis, Bacillus subtilis 168, Bacillus subtilis Thai I-8
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Landowski, C.P.; Lorenzi, P.L.; Song, X.; Amidon, G.L.
Nucleoside ester prodrug substrate specificity of liver carboxylesterase
J. Pharmacol. Exp. Ther.
316
572-580
2006
Sus scrofa
Cummins, I.; Edwards, R.
Purification and cloning of an esterase from the weed black-grass (Alopecurus myosuroides), which bioactivates aryloxyphenoxypropionate herbicides
Plant J.
39
894-904
2004
Alopecurus myosuroides (Q6H8W7), Alopecurus myosuroides
Kaiser, P.; Raina, C.; Parshad, R.; Johri, S.; Verma, V.; Andrabi, K.I.; Qazi, G.N.
A novel esterase from Bacillus subtilis (RRL 1789): purification and characterization of the enzyme
Protein Expr. Purif.
45
262-268
2006
Bacillus subtilis
Zheng, Y.; Lan, W.; Qiao, C.; Mulchandani, A.; Chen, W.
Decontamination of vegetables sprayed with organophosphate pesticides by organophosphorus hydrolase and carboxylesterase (B1)
Appl. Biochem. Biotechnol.
136
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Culex sp.
Elend, C.; Schmeisser, C.; Leggewie, C.; Babiak, P.; Carballeira, J.D.; Steele, H.L.; Reymond, J.; Jaeger, K.; Streit, W.R.
Isolation and biochemical characterization of two novel metagenome-derived esterases
Appl. Environ. Microbiol.
72
3637-3645
2006
unidentified, unidentified soil organism
Boettcher, D.; Bruesehaber, E.; Doderer, K.; Bornscheuer, U.T.
Functional expression of the gamma-isoenzyme of pig liver carboxyl esterase in Escherichia coli
Appl. Microbiol. Biotechnol.
73
1282-1289
2007
Sus scrofa
Kakugawa, S.; Fushinobu, S.; Wakagi, T.; Shoun, H.
Characterization of a thermostable carboxylesterase from the hyperthermophilic bacterium Thermotoga maritima
Appl. Microbiol. Biotechnol.
74
585-591
2007
Thermotoga maritima
Huddleston, S.; Yallop, C.A.; Charalambous, B.M.
The identification and partial characterisation of a novel inducible extracellular thermostable esterase from the archaeon Sulfolobus shibatae.
Biochem. Biophys. Res. Commun.
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Saccharolobus shibatae
Orasmo, G.R.; Oliveira-Collet, S.A.; Lapenta, A.S.; de Fatima P. S. Machado, M.
Biochemical and genetic polymorphisms for carboxylesterase and acetylesterase in grape clones of Vitis vinifera L. (Vitaceae) cultivars
Biochem. Genet.
45
663-670
2007
Vitis vinifera
Sobek, H.; Grisch, H.
Purification and characterization of a heat-stable esterase from the thermoacidophilic archaebacterium Sulfolobus acidocaldarius.
Biochem. J.
250
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1988
Sulfolobus acidocaldarius (Q7M529), Sulfolobus acidocaldarius
Sobek, H.; Grisch, H.
Further kinetic and molecular characterization of an extremely heat-stable carboxylesterase from the thermoacidophilic archaebacterium Sulfolobus acidocaldarius.
Biochem. J.
261
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1989
Sulfolobus acidocaldarius (Q7M529), Sulfolobus acidocaldarius
Ross, M.K.; Borazjani, A.; Edwards, C.C.; Potter, P.M.
Hydrolytic metabolism of pyrethroids by human and other mammalian carboxylesterases
Biochem. Pharmacol.
71
657-669
2006
Oryctolagus cuniculus, Homo sapiens, Rattus norvegicus
Ileperuma, N.R.; Marshall, S.D.; Squire, C.J.; Baker, H.M.; Oakeshott, J.G.; Russell, R.J.; Plummer, K.M.; Newcomb, R.D.; Baker, E.N.
High-resolution crystal structure of plant carboxylesterase AeCXE1, from Actinidia eriantha, and its complex with a high-affinity inhibitor paraoxon
Biochemistry
46
1851-1859
2007
Actinidia eriantha (Q0ZPV7), Actinidia eriantha
Fleming, C.D.; Edwards, C.C.; Kirby, S.D.; Maxwell, D.M.; Potter, P.M.; Cerasoli, D.M.; Redinbo, M.R.
Crystal structures of human carboxylesterase 1 in covalent complexes with the chemical warfare agents soman and tabun
Biochemistry
46
5063-5071
2007
Homo sapiens (P23141), Homo sapiens
Pesaresi, A.; Lambda, D.
Crystallization, X-ray diffraction analysis and phasing of carboxylesterase PA3859 from Pseudomonas aeruginosa
Biochim. Biophys. Acta
1752
197-201
2008
Pseudomonas aeruginosa
Park, Y.; Choi, S.Y.; Lee, H.
A carboxylesterase from the thermoacidophilic archaeon Sulfolobus solfataricus P1; purification, characterization, and expression
Biochim. Biophys. Acta
1760
820-828
2006
Saccharolobus solfataricus, Saccharolobus solfataricus P1
Streit, T.M.; Borazjani, A.; Lentz, S.E.; Wierdl, M.; Potter, P.M.; Gwaltney, S.R.; Ross, M.K.
Evaluation of the side door in carboxylesterase-mediated catalysis and inhibition
Biol. Chem.
389
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Bacillus subtilis
Zhu, Q.G.; Hu, J.H.; Liu, J.Y.; Lu, S.W.; Liu, Y.X.; Wang, J.
Stereoselective characteristics and mechanisms of epidermal carboxylesterase metabolism observed in HaCaT keratinocytes
Biol. Pharm. Bull.
30
532-536
2007
Homo sapiens
Hicks, L.D.; Hyatt, J.L.; Moak, T.; Edwards, C.C.; Tsurkan, L.; Wierdl, M.; Ferreira, A.M.; Wadkins, R.M.; Potter, P.M.
Analysis of the inhibition of mammalian carboxylesterases by novel fluorobenzoins and fluorobenzils
Bioorg. Med. Chem.
15
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2007
Homo sapiens (O00748), Homo sapiens (P23141), Oryctolagus cuniculus (P12337)
Schmidt, M.; Henke, E.; Heinze, B.; Kourist, R.; Hidalgo, A.; Bornscheuer, U.T.
A versatile esterase from Bacillus subtilis: cloning, expression, characterization, and its application in biocatalysis
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Bacillus subtilis (P37967), Bacillus subtilis
Byun, J.; Rhee, J.; Kim, N.D.; Yoon, J.; Kim, D.; Koh, E.; Oh, J.; Cho, H.
Crystal structure of hyperthermophilic esterase EstE1 and the relationship between its dimerization and thermostability properties
BMC Struct. Biol.
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2007
2007
unidentified
Wierdl, M.; Tsurkan, L.; Hyatt, J.L.; Edwards, C.C.; Hatfield, M.J.; Morton, C.L.; Houghton, P.J.; Danks, M.K.; Redinbo, M.R.; Potter, P.M.
An improved human carboxylesterase for enzyme/prodrug therapy with CPT-11
Cancer Gene Ther.
15
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2008
Oryctolagus cuniculus (P12337), Oryctolagus cuniculus, Homo sapiens (P23141), Homo sapiens
Schuette, M.; Fetzner, S.
EstA from Arthrobacter nitroguajacolicus Rue61a, a thermo- and solvent-tolerant carboxylesterase related to class C beta-lactamases
Curr. Microbiol.
54
230-236
2007
Paenarthrobacter nitroguajacolicus
Imai, T.; Taketani, M.; Shii, M.; Hosokawa, M.; Chiba, K.
Substrate specificity of carboxylesterase isozymes and their contribution to hydrolase activity in human liver and small intestine
Drug Metab. Dispos.
34
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2006
Homo sapiens
Wheelock, C.E.; Miller, J.L.; Miller, M.J.; Phillips, B.M.; Huntley, S.A.; Gee, S.J.; Tjeerdema, R.S.; Hammock, B.D.
Use of carboxylesterase activity to remove pyrethroid-associated toxicity to Ceriodaphnia dubia and Hyalella azteca in toxicity identification evaluations
Environ. Toxicol. Chem.
25
973-984
2006
Sus scrofa
Suzuki, Y.; Miyamoto, K.; Ohta, H.
A novel thermostable esterase from the thermoacidophilic archaeon Sulfolobus tokodaii strain 7.
FEMS Microbiol. Lett.
236
97-102
2004
Sulfurisphaera tokodaii (Q976W8), Sulfurisphaera tokodaii 7 (Q976W8)
Morana, A.; Di Prizito, N.; Aurilia, V.; Rossi, M.; Cannio, R.
A carboxylesterase from the hyperthermophilic archaeon Sulfolobus solfataricus: cloning of the gene, characterization of the protein.
Gene
283
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2002
Saccharolobus solfataricus, Saccharolobus solfataricus MT4
Elmi, F.; Lee, H.T.; Huang, J.Y.; Hsieh, Y.C.; Wang, Y.L.; Chen, Y.J.; Shaw, S.Y.; Chen, C.J.
Stereoselective esterase from Pseudomonas putida IFO12996 reveals alpha/beta hydrolase folds for D-beta-acetylthioisobutyric acid synthesis.
J. Bacteriol.
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2005
Pseudomonas putida (Q3HWU8), Pseudomonas putida IFO12996 (Q3HWU8), Pseudomonas putida IFO12996
Wilhelm, S.; Gdynia, A.; Tielen, P.; Rosenau, F.; Jaeger, K.E.
The autotransporter esterase EstA of Pseudomonas aeruginosa is required for rhamnolipid production, cell motility, and biofilm formation
J. Bacteriol.
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2007
Pseudomonas aeruginosa
Ross, M.K.; Crow, J.A.
Human carboxylesterases and their role in xenobiotic and endobiotic metabolism
J. Biochem. Mol. Toxicol.
21
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2007
Homo sapiens
Lun, S.; Bishai, W.R.
Characterization of a novel cell wall-anchored protein with carboxylesterase activity required for virulence in Mycobacterium tuberculosis
J. Biol. Chem.
282
18348-18356
2007
Mycobacterium tuberculosis
Gershater, M.C.; Cummins, I.; Edwards, R.
Role of a carboxylesterase in herbicide bioactivation in Arabidopsis thaliana
J. Biol. Chem.
282
21460-21466
2007
Arabidopsis thaliana
Maqbool, Q.U.; Johri, S.; Rasool, S.; Riyaz-ul-Hassan, S.; Verma, V.; Nargotra, A.; Koul, S.; Qazi, G.N.
Molecular cloning of carboxylesterase gene and biochemical characterization of encoded protein from Bacillus subtilis (RRL BB1)
J. Biotechnol.
125
1-10
2006
Bacillus subtilis (Q4PNS3), Bacillus subtilis
Hyatt, J.L.; Moak, T.; Hatfield, M.J.; Tsurkan, L.; Edwards, C.C.; Wierdl, M.; Danks, M.K.; Wadkins, R.M.; Potter, P.M.
Selective inhibition of carboxylesterases by isatins, indole-2,3-diones
J. Med. Chem.
50
1876-1885
2007
Oryctolagus cuniculus, Homo sapiens (P23141)
Barthel, B.L.; Torres, R.C.; Hyatt, J.L.; Edwards, C.C.; Hatfield, M.J.; Potter, P.M.; Koch, T.H.
Identification of human intestinal carboxylesterase as the primary enzyme for activation of a doxazolidine carbamate prodrug
J. Med. Chem.
51
298-304
2008
Homo sapiens
Park, H.; Kim, Y.; Kim, H.
Expression and characterization of a new esterase cloned directly from Agrobacterium tumefaciens genome
J. Microbiol. Biotechnol.
16
145-148
2006
Agrobacterium tumefaciens
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Bencharit, S.; Edwards, C.C.; Morton, C.L.; Howard-Williams, E.L.; Kuhn, P.; Potter, P.M.; Redinbo, M.R.
Multisite promiscuity in the processing of endogenous substrates by human carboxylesterase 1
J. Mol. Biol.
363
201-214
2006
Homo sapiens
Liu, P.; Ewis, H.E.; Tai, P.C.; Lu, C.D.; Weber, I.T.
Crystal structure of the Geobacillus stearothermophilus carboxylesterase Est55 and its activation of prodrug CPT-11
J. Mol. Biol.
367
212-223
2007
Geobacillus stearothermophilus
Schiel, M.A.; Green, S.L.; Davis, W.I.; Sanghani, P.C.; Bosron, W.F.; Sanghani, S.P.
Expression and characterization of a human carboxylesterase 2 splice variant
J. Pharmacol. Exp. Ther.
323
94-101
2007
Homo sapiens
Taketani, M.; Shii, M.; Ohura, K.; Ninomiya, S.; Imai, T.
Carboxylesterase in the liver and small intestine of experimental animals and human
Life Sci.
81
924-932
2007
Canis lupus familiaris, Oryctolagus cuniculus, Homo sapiens, Rattus norvegicus
Sehgal, A.C.; Callen, W.; Mathur, E.J.; Short, J.M.; Kelly, R.M.
Carboxylesterase from Sulfolobus solfataricus P1.
Methods Enzymol.
330
461-471
2001
Saccharolobus solfataricus, Saccharolobus solfataricus P1
Wadkins, R.M.; Hyatt, J.L.; Edwards, C.C.; Tsurkan, L.; Redinbo, M.R.; Wheelock, C.E.; Jones, P.D.; Hammock, B.D.; Potter, P.M.
Analysis of mammalian carboxylesterase inhibition by trifluoromethylketone-containing compounds
Mol. Pharmacol.
71
713-723
2007
Homo sapiens (O00748), Homo sapiens (P23141), Homo sapiens, Oryctolagus cuniculus (P12337)
Cummins, I.; Landrum, M.; Steel, P.G.; Edwards, R.
Structure activity studies with xenobiotic substrates using carboxylesterases isolated from Arabidopsis thaliana
Phytochemistry
68
811-818
2007
Arabidopsis thaliana
Cummins, I.; Steel, P.G.; Edwards, R.
Identification of a carboxylesterase expressed in protoplasts using fluorescence-activated cell sorting
Plant Biotechnol. J.
5
354-359
2007
Arabidopsis thaliana
Crow, J.A.; Borazjani, A.; Potter, P.M.; Ross, M.K.
Hydrolysis of pyrethroids by human and rat tissues: examination of intestinal, liver and serum carboxylesterases
Toxicol. Appl. Pharmacol.
221
1-12
2007
Homo sapiens, Rattus norvegicus (O70177)
Jewell, C.; Prusakiewicz, J.J.; Ackermann, C.; Payne, N.A.; Fate, G.; Williams, F.M.
The distribution of esterases in the skin of the minipig
Toxicol. Lett.
173
118-123
2007
Sus scrofa
Zhu, H.J.; Patrick, K.S.; Yuan, H.J.; Wang, J.S.; Donovan, J.L.; DeVane, C.L.; Malcolm, R.; Johnson, J.A.; Youngblood, G.L.; Sweet, D.H.; Langaee, T.Y.; Markowitz, J.S.
Two CES1 gene mutations lead to dysfunctional carboxylesterase 1 activity in man: clinical significance and molecular basis
Am. J. Hum. Genet.
82
1241-1248
2008
Homo sapiens (P23141), Homo sapiens
Pena-Montes, C.; Gonzalez, A.; Castro-Ochoa, D.; Farres, A.
Purification and biochemical characterization of a broad substrate specificity thermostable alkaline protease from Aspergillus nidulans
Appl. Microbiol. Biotechnol.
78
603-612
2008
Aspergillus nidulans, Aspergillus nidulans PW1
Yoshimura, M.; Kimura, T.; Ishii, M.; Ishii, K.; Matsuura, T.; Geshi, E.; Hosokawa, M.; Muramatsu, M.
Functional polymorphisms in carboxylesterase 1A2 (CES1A2) gene involves specific protein 1 (Sp1) binding sites
Biochem. Biophys. Res. Commun.
369
939-942
2008
Homo sapiens
Mello, T.; Nakatsuka, A.; Fears, S.; Davis, W.; Tsukamoto, H.; Bosron, W.F.; Sanghani, S.P.
Expression of carboxylesterase and lipase genes in rat liver cell-types
Biochem. Biophys. Res. Commun.
374
460-464
2008
Rattus norvegicus (O70631)
Zhu, H.J.; Appel, D.I.; Johnson, J.A.; Chavin, K.D.; Markowitz, J.S.
Role of carboxylesterase 1 and impact of natural genetic variants on the hydrolysis of trandolapril
Biochem. Pharmacol.
77
1266-1272
2009
Homo sapiens
Yang, D.; Pearce, R.E.; Wang, X.; Gaedigk, R.; Wan, Y.J.; Yan, B.
Human carboxylesterases HCE1 and HCE2: ontogenic expression, inter-individual variability and differential hydrolysis of oseltamivir, aspirin, deltamethrin and permethrin
Biochem. Pharmacol.
77
238-247
2009
Homo sapiens
Crow, J.A.; Middleton, B.L.; Borazjani, A.; Hatfield, M.J.; Potter, P.M.; Ross, M.K.
Inhibition of carboxylesterase 1 is associated with cholesteryl ester retention in human THP-1 monocyte/macrophages
Biochim. Biophys. Acta
1781
643-654
2008
Homo sapiens
Tanino, T.; Nawa, A.; Miki, Y.; Iwaki, M.
Enzymatic stability of 2-ethylcarbonate-linked paclitaxel in serum and conversion to paclitaxel by rabbit liver carboxylesterase for use in prodrug/enzyme therapy
Biopharm. Drug Dispos.
29
259-269
2008
Oryctolagus cuniculus, Homo sapiens, Rattus norvegicus
Tang, X.; Wu, H.; Wu, Z.; Wang, G.; Wang, Z.; Zhu, D.
Carboxylesterase 2 is downregulated in colorectal cancer following progression of the disease
Cancer Invest.
26
178-181
2008
Homo sapiens
Byun, H.M.; Choi, S.H.; Laird, P.W.; Trinh, B.; Siddiqui, M.A.; Marquez, V.E.; Yang, A.S.
2-Deoxy-N4-[2-(4-nitrophenyl)ethoxycarbonyl]-5-azacytidine: a novel inhibitor of DNA methyltransferase that requires activation by human carboxylesterase 1
Cancer Lett.
266
238-248
2008
Homo sapiens
Yano, H.; Kayukawa, S.; Iida, S.; Nakagawa, C.; Oguri, T.; Sanda, T.; Ding, J.; Mori, F.; Ito, A.; Ri, M.; Inagaki, A.; Kusumoto, S.; Ishida, T.; Komatsu, H.; Inagaki, H.; Suzuki, A.; Ueda, R.
Overexpression of carboxylesterase-2 results in enhanced efficacy of topoisomerase I inhibitor, irinotecan (CPT-11), for multiple myeloma
Cancer Sci.
99
2309-2314
2008
Homo sapiens
Pan, Y.; Guo, H.; Gao, X.
Carboxylesterase activity, cDNA sequence, and gene expression in malathion susceptible and resistant strains of the cotton aphid, Aphis gossypii
Comp. Biochem. Physiol. B
152
266-270
2009
Aphis gossypii (O76177), Aphis gossypii
Williams, E.T.; Jones, K.O.; Ponsler, G.D.; Lowery, S.M.; Perkins, E.J.; Wrighton, S.A.; Ruterbories, K.J.; Kazui, M.; Farid, N.A.
The biotransformation of prasugrel, a new thienopyridine prodrug, by the human carboxylesterases 1 and 2
Drug Metab. Dispos.
36
1227-1232
2008
Homo sapiens
Hosokawa, M.; Furihata, T.; Yaginuma, Y.; Yamamoto, N.; Watanabe, N.; Tsukada, E.; Ohhata, Y.; Kobayashi, K.; Satoh, T.; Chiba, K.
Structural organization and characterization of the regulatory element of the human carboxylesterase (CES1A1 and CES1A2) genes
Drug Metab. Pharmacokinet.
23
73-84
2008
Homo sapiens (P23141), Homo sapiens
Laguerre, C.; Sanchez-Hernandez, J.C.; Koehler, H.R.; Triebskorn, R.; Capowiez, Y.; Rault, M.; Mazzia, C.
B-type esterases in the snail Xeropicta derbentina: an enzymological analysis to evaluate their use as biomarkers of pesticide exposure
Environ. Pollut.
157
199-207
2009
Xeropicta derbentina
Sanchez-Hernandez, J.C.; Wheelock, C.E.
Tissue distribution, isozyme abundance and sensitivity to chlorpyrifos-oxon of carboxylesterases in the earthworm Lumbricus terrestris
Environ. Pollut.
157
264-272
2008
Lumbricus terrestris
Cordova, J.; Ryan, J.D.; Boonyaratanakornkit, B.B.; Clark, D.S.
Esterase activity of bovine serum albumin up to 160 C: A new benchmark for biocatalysis
Enzyme Microb. Technol.
42
278-283
2008
Bos taurus
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Esterase SeE of Streptococcus equi ssp. equi is a novel nonspecific carboxylic ester hydrolase
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Oryctolagus cuniculus, Homo sapiens
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Haloarcula marismortui (Q5V5N6), Haloarcula marismortui, Haloarcula marismortui DSM 3752 (Q5V5N6)
Liu, C.; Yang, G.; Wu, L.; Tian, G.; Zhang, Z.; Feng, Y.
Switch of substrate specificity of hyperthermophilic acylaminoacyl peptidase by combination of protein and solvent engineering
Protein Cell
2
497-506
2011
Aeropyrum pernix (Q9YBQ2), Aeropyrum pernix DSM 11879 (Q9YBQ2)
Greenblatt, H.M.; Otto, T.C.; Kirkpatrick, M.G.; Kovaleva, E.; Brown, S.; Buchman, G.; Cerasoli, D.M.; Sussman, J.L.
Structure of recombinant human carboxylesterase 1 isolated from whole cabbage looper larvae
Acta Crystallogr. Sect. F
68
269-272
2012
Homo sapiens (P23141), Homo sapiens
Amissah, F.; Duverna, R.; Aguilar, B.J.; Poku, R.A.; Kiros, G.E.; Lamango, N.S.
Polyisoprenylated methylated protein methyl esterase overexpression and hyperactivity promotes lung cancer progression
Am. J. Cancer Res.
4
116-134
2014
Homo sapiens
Kim, J.; Kim, S.; Yoon, S.; Hong, E.; Ryu, Y.
Improved enantioselectivity of thermostable esterase from Archaeoglobus fulgidus toward (S)-ketoprofen ethyl ester by directed evolution and characterization of mutant esterases
Appl. Microbiol. Biotechnol.
99
6293-301
2015
Archaeoglobus fulgidus
Dou, S.; Kong, X.D.; Ma, B.D.; Chen, Q.; Zhang, J.; Zhou, J.; Xu, J.H.
Crystal structures of Pseudomonas putida esterase reveal the functional role of residues 187 and 287 in substrate binding and chiral recognition
Biochem. Biophys. Res. Commun.
446
1145-1150
2014
Pseudomonas putida, Pseudomonas putida ECU1011
Xiang, D.F.; Kumaran, D.; Swaminathan, S.; Raushel, F.M.
Structural characterization and function determination of a nonspecific carboxylate esterase from the amidohydrolase superfamily with a promiscuous ability to hydrolyze methylphosphonate esters
Biochemistry
53
3476-3485
2014
Cereibacter sphaeroides
Amissah, F.; Duverna, R.; Aguilar, B.J.; Poku, R.A.; Lamango, N.S.
Polyisoprenylated methylated protein methyl esterase is both sensitive to curcumin and overexpressed in colorectal cancer: implications for chemoprevention and treatment
BioMed Res. Int.
2013
416534
2013
Homo sapiens
Xie, Z.; Xu, B.; Ding, J.; Liu, L.; Zhang, X.; Li, J.; Huang, Z.
Heterologous expression and characterization of a malathion-hydrolyzing carboxylesterase from a thermophilic bacterium, Alicyclobacillus tengchongensis
Biotechnol. Lett.
35
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2013
Alicyclobacillus tengchongensis (S4TYB2), Alicyclobacillus tengchongensis, Alicyclobacillus tengchongensis D-1 (S4TYB2)
Wei, Y.; Peng, A.Y.; Huang, J.
Inhibition of porcine liver carboxylesterase by phosphorylated flavonoids
Chem. Biol. Interact.
204
75-79
2013
Sus scrofa
Thomsen, R.; Rasmussen, H.B.; Linnet, K.; Linnet, K.
In vitro drug metabolism by human carboxylesterase 1: focus on angiotensin-converting enzyme inhibitors
Drug Metab. Dispos.
42
126-133
2014
Homo sapiens
Golyshina, O.V.; Golyshin, P.N.; Timmis, K.N.; Ferrer, M.
The 'pH optimum anomaly' of intracellular enzymes of Ferroplasma acidiphilum
Environ. Microbiol.
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2006
Ferroplasma acidiphilum (Q2PCE5), Ferroplasma acidiphilum
Ayuk-Takem, L.; Amissah, F.; Aguilar, B.J.; Lamango, N.S.
Inhibition of polyisoprenylated methylated protein methyl esterase by synthetic musks induces cell degeneration
Environ. Toxicol.
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2014
Homo sapiens, Sus scrofa
Coppin, C.W.; Jackson, C.J.; Sutherland, T.; Hart, P.J.; Devonshire, A.L.; Russell, R.J.; Oakeshott, J.G.
Testing the evolvability of an insect carboxylesterase for the detoxification of synthetic pyrethroid insecticides
Insect Biochem. Mol. Biol.
42
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2012
Lucilia cuprina (Q25252), Lucilia cuprina
He, P.; Zhang, Y.N.; Li, Z.Q.; Yang, K.; Zhu, J.Y.; Liu, S.J.; Dong, S.L.
An antennae-enriched carboxylesterase from Spodoptera exigua displays degradation activity in both plant volatiles and female sex pheromones
Insect Mol. Biol.
23
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2014
Spodoptera exigua
Shao, H.; Xu, L.; Yan, Y.
Biochemical characterization of a carboxylesterase from the archaeon Pyrobaculum sp. 1860 and a rational explanation of its substrate specificity and thermostability
Int. J. Mol. Sci.
15
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2014
Pyrobaculum sp. (G7VG08), Pyrobaculum sp. 1860 (G7VG08)
Ohara, K.; Unno, H.; Oshima, Y.; Hosoya, M.; Fujino, N.; Hirooka, K.; Takahashi, S.; Yamashita, S.; Kusunoki, M.; Nakayama, T.
Structural insights into the low pH adaptation of a unique carboxylesterase from Ferroplasma: altering the pH optima of two carboxylesterases
J. Biol. Chem.
289
24499-24510
2014
Ferroplasma acidiphilum (Q2PCE5), Ferroplasma acidiphilum, Saccharolobus shibatae (Q5NU42), Saccharolobus shibatae, Saccharolobus shibatae DSM 5389 (Q5NU42)
del Loandos, M.H.; Muro, A.C.; Villecco, M.B.; Masman, M.F.; Luiten, P.G.; Andujar, S.A.; Suvirec, F.D.; Enriz, R.D.
Catalytic and molecular properties of rabbit liver carboxylesterase acting on 1,8-cineole derivatives
Nat. Prod. Commun.
7
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2012
Oryctolagus cuniculus
Jackson, C.J.; Liu, J.W.; Carr, P.D.; Younus, F.; Coppin, C.; Meirelles, T.; Lethier, M.; Pandey, G.; Ollis, D.L.; Russell, R.J.; Weik, M.; Oakeshott, J.G.
Structure and function of an insect alpha-carboxylesterase (alphaEsterase7) associated with insecticide resistance
Proc. Natl. Acad. Sci. USA
110
10177-10182
2013
Lucilia cuprina (Q25252)
Hiblot, J.; Bzdrenga, J.; Champion, C.; Chabriere, E.; Elias, M.
Crystal structure of VmoLac, a tentative quorum quenching lactonase from the extremophilic crenarchaeon Vulcanisaeta moutnovskia
Sci. Rep.
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8372
2015
Vulcanisaeta moutnovskia (F0QXN6), Vulcanisaeta moutnovskia 768-28 (F0QXN6)
Zhuang, X.M.; Wei, X.; Tan, Y.; Xiao, W.B.; Yang, H.Y.; Xie, J.W.; Lu, C.; Li, H.
Contribution of carboxylesterase and cytochrome P450 to the bioactivation and detoxification of isocarbophos and its enantiomers in human liver microsomes
Toxicol. Sci.
140
40-48
2014
Homo sapiens
Li, X.J.; Zheng, R.C.; Wu, Z.M.; Ding, X.; Zheng, Y.G.
Thermophilic esterase from Thermomyces lanuginosus molecular cloning, functional expression and biochemical characterization
Protein Expr. Purif.
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2014
Thermomyces lanuginosus (W8DVW0), Thermomyces lanuginosus, Thermomyces lanuginosus DSM 10635 (W8DVW0), Thermomyces lanuginosus DSM 10635
Almeida, R.; Alqueres, S.; Larentis, A.; Rssle, S.; Cardoso, A.; Almeida, W.; Bisch, P.; Alves, T.; Martins, O.
Cloning, expression, partial characterization and structural modeling of a novel esterase from Pyrococcus furiosus
Enzyme Microb. Technol.
39
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2006
Pyrococcus furiosus (Q8TZJ1)
-
Branco, R.; Estrada Gutarra, M.; Freire, D.; Almeida, R.
Immobilization and characterization of a recombinant thermostable lipase (Pf2001) from pyrococcus furiosus on supports with different degrees of hydrophobicity
Enzyme Res.
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180418
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Pyrococcus furiosus (Q8TZJ1)
Varejao, N.; De-Andrade, R.; Almeida, R.; Anobom, C.; Foguel, D.; Reverter, D.
Structural mechanism for the temperature-dependent activation of the hyperthermophilic Pf2001 esterase
Structure
26
199-208.e3
2018
Pyrococcus furiosus (Q8TZJ1), Pyrococcus furiosus
Fucinos, P.; Pastrana, L.; Sanroman, A.; Longo, M.; Hermoso, J.; Rua, M.
An esterase from Thermus thermophilus HB27 with hyper-thermoalkalophilic properties Purification, characterisation and structural modelling
J. Mol. Catal. B
70
127-137
2011
Thermus thermophilus (Q72J75)
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Fucinos, P.; Atanes, E.; Lopez-Lopez, O.; Solaroli, M.; Cerdan, M.; Gonzalez-Siso, M.; Pastrana, L.; Rua, M.
Cloning, expression, purification and characterization of an oligomeric His-tagged thermophilic esterase from Thermus thermophilus HB27
Process Biochem.
49
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2014
Thermus thermophilus (Q72J75)
-
Huang, J.; Zhang, Y.; Hu, Y.
Functional characterization of a marine Bacillus esterase and its utilization in the stereo-selective production of D-methyl lactate
Appl. Biochem. Biotechnol.
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1467-1481
2016
Bacillus sp. SCSIO 15121 (A0A1B2BII0)
Yan, X.; Wang, J.; Sun, Y.; Zhu, J.; Wu, S.
Facilitating the evolution of esterase activity from a promiscuous enzyme (Mhg) with catalytic functions of amide hydrolysis and carboxylic acid perhydrolysis by engineering the substrate entrance tunnel
Appl. Environ. Microbiol.
82
6748-6756
2016
Microbacterium hydrocarbonoxydans, Microbacterium hydrocarbonoxydans NBRC 103074
Adesioye, F.A.; Makhalanyane, T.P.; Vikram, S.; Sewell, B.T.; Schubert, W.D.; Cowan, D.A.
Structural characterization and directed evolution of a novel acetyl xylan esterase reveals thermostability determinants of the carbohydrate esterase 7 family
Appl. Environ. Microbiol.
84
e02695-17
2018
uncultured bacterium
Alves, M.; Lamego, J.; Bandeiras, T.; Castro, R.; Tomas, H.; Coroadinha, A.S.; Costa, J.; Simplicio, A.L.
Human carboxylesterase 2 studies on the role of glycosylation for enzymatic activity
Biochem. Biophys. Rep.
5
105-110
2016
Homo sapiens (O00748), Homo sapiens
Kabeya, T.; Matsumura, W.; Iwao, T.; Hosokawa, M.; Matsunaga, T.
Functional analysis of carboxylesterase in human induced pluripotent stem cell-derived enterocytes
Biochem. Biophys. Res. Commun.
486
143-148
2017
Homo sapiens, Homo sapiens (Q6LAP9)
Sungkeeree, P.; Toewiwat, N.; Whangsuk, W.; Ploypradith, P.; Mongkolsuk, S.; Loprasert, S.
The esterase B from Sphingobium sp. SM42 has the new de-arenethiolase activity against cephalosporin antibiotics
Biochem. Biophys. Res. Commun.
506
231-236
2018
Sphingobium sp. SM42 (A0A0C5DFF8)
Weng, Z.M.; Ge, G.B.; Dou, T.Y.; Wang, P.; Liu, P.K.; Tian, X.H.; Qiao, N.; Yu, Y.; Zou, L.W.; Zhou, Q.; Zhang, W.D.; Hou, J.
Characterization and structure-activity relationship studies of flavonoids as inhibitors against human carboxylesterase 2
Bioorg. Chem.
77
320-329
2018
Homo sapiens (O00748), Homo sapiens
Shchegolkov, E.V.; Makhaeva, G.F.; Boltneva, N.P.; Lushchekina, S.V.; Serebryakova, O.G.; Rudakova, E.V.; Kovaleva, N.V.; Burgart, Y.V.; Saloutin, V.I.; Chupakhin, O.N.; Bachurin, S.O.; Richardson, R.J.
Synthesis, molecular docking, and biological activity of polyfluoroalkyl dihydroazolo[5,1-c][1,2,4]triazines as selective carboxylesterase inhibitors
Bioorg. Med. Chem.
25
3997-4007
2017
Sus scrofa (A0A287BBZ0)
Takahashi, M.; Ogawa, T.; Kashiwagi, H.; Fukushima, F.; Yoshitsugu, M.; Haba, M.; Hosokawa, M.
Chemical synthesis of an indomethacin ester prodrug and its metabolic activation by human carboxylesterase 1
Bioorg. Med. Chem. Lett.
28
997-1000
2018
Homo sapiens (P23141), Homo sapiens
Wang, C.; Qiu, J.; Yang, Y.; Zheng, J.; He, J.; Li, S.
Identification and characterization of a novel carboxylesterase (FpbH) that hydrolyzes aryloxyphenoxypropionate herbicides
Biotechnol. Lett.
39
553-560
2017
Aquamicrobium sp. FPB-1 (A0A024CDT8)
Wang, L.L.; Lu, X.P.; Smagghe, G.; Meng, L.W.; Wang, J.J.
Functional characterization of BdB1, a well-conserved carboxylesterase among tephritid fruit flies associated with malathion resistance in Bactrocera dorsalis (Hendel)
Comp. Biochem. Physiol. C
200
1-8
2017
Bactrocera dorsalis (A0A034VLA7), Bactrocera dorsalis
Park, K.M.; Lee, J.H.; Hong, S.C.; Kwon, C.W.; Jo, M.; Choi, S.J.; Kim, K.; Chang, P.S.
Selective production of 1-monocaprin by porcine liver carboxylesterase-catalyzed esterification Its enzyme kinetics and catalytic performance
Enzyme Microb. Technol.
82
51-57
2016
Sus scrofa
Zou, L.W.; Li, Y.G.; Wang, P.; Zhou, K.; Hou, J.; Jin, Q.; Hao, D.C.; Ge, G.B.; Yang, L.
Design, synthesis, and structure-activity relationship study of glycyrrhetinic acid derivatives as potent and selective inhibitors against human carboxylesterase 2
Eur. J. Med. Chem.
112
280-288
2016
Homo sapiens (O00748), Homo sapiens (P23141), Homo sapiens
Binder, R.J.; Hatfield, M.J.; Chi, L.; Potter, P.M.
Facile synthesis of 1,2-dione-containing abietane analogues for the generation of human carboxylesterase inhibitors
Eur. J. Med. Chem.
149
79-89
2018
Homo sapiens (P23141), Homo sapiens
Yoshida, T.; Fukami, T.; Kurokawa, T.; Gotoh, S.; Oda, A.; Nakajima, M.
Difference in substrate specificity of carboxylesterase and arylacetamide deacetylase between dogs and humans
Eur. J. Pharm. Sci.
111
167-176
2018
Canis lupus familiaris (F1P6W8), Canis lupus familiaris (Q95N05), Canis lupus familiaris
Miwa, S.; Treumann, A.; Bell, A.; Vistoli, G.; Nelson, G.; Hay, S.; von Zglinicki, T.
Carboxylesterase converts Amplex red to resorufin implications for mitochondrial H2O2 release assays
Free Radic. Biol. Med.
90
173-183
2016
Mus musculus (Q8VCC2), Mus musculus C57BL/6 (Q8VCC2)
Li, D.; Li, Z.; Chen, W.; Yang, X.
Imaging and detection of carboxylesterase in living cells and zebrafish pretreated with pesticides by a new near-infrared fluorescence off-on probe
J. Agric. Food Chem.
65
4209-4215
2017
Danio rerio, Homo sapiens
Baker, A.A.; Guo, G.L.; Aleksunes, L.M.; Richardson, J.R.
Isoform-specific regulation of mouse carboxylesterase expression and activity by prototypical transcriptional activators
J. Biochem. Mol. Toxicol.
29
545-551
2015
Mus musculus (P23953), Mus musculus (Q63880), Mus musculus (Q64176), Mus musculus (Q8VCC2), Mus musculus (Q8VCT4), Mus musculus, Mus musculus C57Bl6/J (P23953), Mus musculus C57Bl6/J (Q63880), Mus musculus C57Bl6/J (Q64176), Mus musculus C57Bl6/J (Q8VCC2), Mus musculus C57Bl6/J (Q8VCT4)
Pauly, J.; Groeger, H.; Patel, A.V.
Design, characterisation and application of alginate-based encapsulated pig liver esterase
J. Biotechnol.
280
42-48
2018
Sus scrofa
Imai, T.; Ariyoshi, S.; Ohura, K.; Sawada, T.; Nakada, Y.
Expression of carboxylesterase isozymes and their role in the behavior of a fexofenadine prodrug in rat skin
J. Pharm. Sci.
105
714-721
2016
Rattus norvegicus (O35535), Rattus norvegicus (O70177), Rattus norvegicus Wistar (O35535), Rattus norvegicus Wistar (O70177)
Yang, X.; Dai, J.; Zhao, S.; Li, R.; Goulette, T.; Chen, X.; Xiao, H.
Identification and characterization of a novel carboxylesterase from Phaseolus vulgaris for detection of organophosphate and carbamates pesticides
J. Sci. Food. Agric.
98
5095-5104
2018
Phaseolus vulgaris
Espinosa-Luna, G.; Sanchez-Otero, M.G.; Quintana-Castro, R.; Matus-Toledo, R.E.; Oliart-Ros, R.M.
Gene cloning and characterization of the Geobacillus thermoleovorans CCR11 carboxylesterase CaesCCR11, a new member of family XV
Mol. Biotechnol.
58
37-46
2016
Geobacillus thermoleovorans (W8QMJ2), Geobacillus thermoleovorans CCR11 (W8QMJ2), Geobacillus thermoleovorans CCR11
Mustafa, S.A.
The development of bacterial carboxylesterase biological recognition elements for cocaine detection
Mol. Biotechnol.
60
601-607
2018
Bacillus subtilis subsp. subtilis (P37967), Bacillus licheniformis (Q65MY7), Bacillus licheniformis NCIMB 9375 (Q65MY7), Bacillus licheniformis Gibson 46 (Q65MY7), Bacillus licheniformis JCM 2505 (Q65MY7), Bacillus licheniformis NRRL NRS-1264 (Q65MY7), Bacillus licheniformis NBRC 12200 (Q65MY7), Bacillus licheniformis ATCC 14580 (Q65MY7), Bacillus subtilis subsp. subtilis 168 (P37967), Bacillus licheniformis DSM 13 (Q65MY7)
Igawa, Y.; Fujiwara, S.; Ohura, K.; Hirokawa, T.; Nishizawa, Y.; Uehara, S.; Uno, Y.; Imai, T.
Differences in intestinal hydrolytic activities between cynomolgus monkeys and humans evaluation of substrate specificities using recombinant carboxylesterase 2 isozymes
Mol. Pharm.
13
3176-3186
2016
Macaca fascicularis (A0A2K5V282), Macaca fascicularis, Homo sapiens (O00748), Homo sapiens
Yao, J.; Chen, X.; Zheng, F.; Zhan, C.G.
Catalytic reaction mechanism for drug metabolism in human carboxylesterase-1 cocaine hydrolysis pathway
Mol. Pharm.
15
3871-3880
2018
Homo sapiens (P23141), Homo sapiens
Seo, H.H.; Park, A.R.; Lee, H.H.; Park, S.; Han, Y.J.; Hoang, Q.T.N.; Choi, G.J.; Kim, J.C.; Kim, Y.S.; Kim, J.I.
A fungus-inducible pepper carboxylesterase exhibits antifungal activity by decomposing the outerlayer of fungal cell walls
Mol. Plant Microbe Interact.
31
505-515
2018
Capsicum annuum (Q9LM08)
Igetei, J.E.; Liddell, S.; El-Faham, M.; Doenhoff, M.J.
Purification of a chymotrypsin-like enzyme present on adult Schistosoma mansoni worms from infected mice and its characterization as a host carboxylesterase
Parasitology
143
646-657
2016
Rattus norvegicus (P10959), Mus musculus (P23953), Mus musculus
He, P.; Zhang, Y.N.; Yang, K.; Li, Z.Q.; Dong, S.L.
An antenna-biased carboxylesterase is specifically active to plant volatiles in Spodoptera exigua
Pestic. Biochem. Physiol.
123
93-100
2015
Spodoptera exigua
Wang, A.H.; Tian, X.G.; Cui, Y.L.; Huo, X.K.; Zhang, B.J.; Deng, S.; Feng, L.; Ma, X.C.; Jia, J.M.; Wang, C.
Diterpenoids from the roots of Euphorbia ebracteolata and their inhibitory effects on human carboxylesterase 2
Phytochemistry
146
82-90
2018
Homo sapiens (O00748), Homo sapiens
Chen, C.; Liu, Y.; Shi, X.; Desneux, N.; Han, P.; Gao, X.
Elevated carboxylesterase activity contributes to the lambda-cyhalothrin insensitivity in quercetin fed Helicoverpa armigera (Huebner)
PLoS ONE
12
e0183111
2017
Helicoverpa armigera
Boonyuen, U.; Promnares, K.; Junkree, S.; Day, N.; Imwong, M.
Efficient in vitro refolding and functional characterization of recombinant human liver carboxylesterase (CES1) expressed in E. coli
Protein Expr. Purif.
107
68-75
2015
Homo sapiens (P23141), Homo sapiens
Cai, X.; Wang, W.; Lin, L.; He, D.; Huang, G.; Shen, Y.; Wei, W.; Wei, D.
Autotransporter domain-dependent enzymatic analysis of a novel extremely thermostable carboxylesterase with high biodegradability towards pyrethroid pesticides
Sci. Rep.
7
3461
2017
Pseudomonas synxantha (A0A0K0Q1Y2), Pseudomonas synxantha, Pseudomonas synxantha PS1 (A0A0K0Q1Y2)
Correy, G.J.; Carr, P.D.; Meirelles, T.; Mabbitt, P.D.; Fraser, N.J.; Weik, M.; Jackson, C.J.
Mapping the accessible conformational landscape of an insect carboxylesterase using conformational ensemble analysis and kinetic crystallography
Structure
24
977-987
2016
Lucilia cuprina (Q25252)
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