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Disease on EC 2.8.2.9 - tyrosine-ester sulfotransferase

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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Acute Kidney Injury
Hepatic sulfotransferase as a nephropreventing target by suppression of the uremic toxin indoxyl sulfate accumulation in ischemic acute kidney injury.
Suppressed Hepatic Production of Indoxyl Sulfate Attenuates Cisplatin-Induced Acute Kidney Injury in Sulfotransferase 1a1-Deficient Mice.
Adenocarcinoma
Analysis of A4gnt Knockout Mice Reveals an Essential Role for Gastric Sulfomucins in Preventing Gastritis Cystica Profunda.
Association of elevated sulfatides and sulfotransferase activities with human renal cell carcinoma.
Cloning and expression of cDNA encoding human placental estrogen sulfotransferase.
Human uterine endometrial adenocarcinoma: characteristic acquirement of synthetic potentials for II3SO3-LacCer and ganglio series sulfoglycosphingolipids after transfer of the cancer cells to culture.
O-glycan biosynthesis in human colorectal adenoma cells during progression to cancer.
Adenocarcinoma, Mucinous
Specificities of N-acetylglucosamine-6-O-sulfotransferases in relation to L-selectin ligand synthesis and tumor-associated enzyme expression.
Alopecia
Characterization of follicular minoxidil sulfotransferase activity in a cohort of pattern hair loss patients from the Indian Subcontinent.
Doppler laser imaging predicts response to topical minoxidil in the treatment of female pattern hair loss.
Microneedling improves minoxidil response in androgenetic alopecia patients by upregulating follicular sulfotransferase enzymes.
Novel topical booster enhances follicular sulfotransferase activity in patients with androgenetic alopecia: a new strategy to improve minoxidil response.
Oral minoxidil bio-activation by hair follicle outer root sheath cell sulfotransferase enzymes predicts clinical efficacy in female pattern hair loss.
Sulfotransferase activity in plucked hair follicles predicts response to topical minoxidil in the treatment of female androgenetic alopecia.
Sulfotransferase activity in plucked hair follicles predicts response to topical minoxidil treatment in Brazilian female pattern hair loss patients.
The effect of topical minoxidil treatment on follicular sulfotransferase enzymatic activity.
Tretinoin enhances minoxidil response in androgenetic alopecia patients by upregulating follicular sulfotransferase enzymes.
Alzheimer Disease
Reduced sulfotransferase SULT2A1 activity in patients with Alzheimer's disease.
Arthritis, Rheumatoid
A HEV-restricted sulfotransferase is expressed in rheumatoid arthritis synovium and is induced by lymphotoxin-alpha/beta and TNF-alpha in cultured endothelial cells.
Asthma
Analyses of shared genetic factors between asthma and obesity in children.
Brain Diseases
Molecular analysis of carbohydrate N-acetylgalactosamine 4-O sulfotransferase 8 (CHST8) as a candidate gene for bovine spongiform encephalopathy susceptibility.
Breast Neoplasms
Association between SULT1A1 Arg213His (rs9282861) Polymorphism and Risk of Breast Cancer: A Systematic Review and Meta-Analysis.
Association of sulfotransferase SULT1A1 with breast cancer risk: a meta-analysis of case-control studies with subgroups of ethnic and menopausal statue.
Biological effects of progestins in breast cancer.
Biological responses of progestogen metabolites in normal and cancerous human breast.
Biotransformation of melatonin in human breast cancer cell lines: role of sulfotransferase 1A1.
Breast cancer treatment and sulfotransferase.
Chondroitin sulfates play a major role in breast cancer metastasis: a role for CSPG4 and CHST11 gene expression in forming surface P-selectin ligands in aggressive breast cancer cells.
Control of sulfatase and sulfotransferase activities by medrogestone in the hormone-dependent MCF-7 and T-47D human breast cancer cell lines.
Correlation of estrogen sulfotransferase activity and proliferation in normal and carcinomatous human breast. A hypothesis.
CYP2D6 genotype, antidepressant use, and tamoxifen metabolism during adjuvant breast cancer treatment.
Differential expression pattern of estrogen receptors, aromatase, and sulfotransferase in breast cancer tissue and corresponding lymph node metastases.
Effect of nomegestrol acetate on estrogen biosynthesis and transformation in MCF-7 and T47-D breast cancer cells.
Effect of nomegestrol acetate on human estrogen sulfotransferase activity in the hormone-dependent MCF-7 and T-47D breast cancer cell lines.
Estradiol-17beta sulfotransferase activity in canine osteosarcoma D17 cells.
Estrogen sulfotransferases in breast and endometrial cancers.
Estrone sulfatase versus estrone sulfotransferase in human breast cancer: potential clinical applications.
Expression of aromatase and estrogen sulfotransferase in preinvasive and invasive breast cancer.
Expression of sulfotransferase isoform 1A1 (SULT1A1) in breast cancer cells significantly increases 4-hydroxytamoxifen-induced apoptosis.
Genetic polymorphisms of drug-metabolising enzymes and drug transporters in the chemotherapeutic treatment of cancer.
Human estrogen sulfotransferase (hEST1) activities and its mRNA in various breast cancer cell lines. Effect of the progestin, promegestone (R-5020).
Intratumoural mRNA expression of genes from the oestradiol metabolic pathway and clinical and histopathological parameters of breast cancer.
New developments in intracrinology of human breast cancer: estrogen sulfatase and sulfotransferase.
Phenol sulfotransferases: hormonal regulation, polymorphism, and age of onset of breast cancer.
Progestins and breast cancer.
Recent insight on the control of enzymes involved in estrogen formation and transformation in human breast cancer.
Resveratrol modulates human mammary epithelial cell O-acetyltransferase, sulfotransferase, and kinase activation of the heterocyclic amine carcinogen N-hydroxy-PhIP.
Selective spatial upregulation of intratumoral stromal aromatase in breast cancer patients: evidence for imbalance of local estrogen metabolism.
Sex-specific expression mechanism of hepatic estrogen inactivating enzyme and transporters in diabetic women.
Sulfation through the looking glass--recent advances in sulfotransferase research for the curious.
Sulfotransferase 1A2*2 is a risk factor for early-onset breast cancer.
The metabolism and analysis of isoflavones and other dietary polyphenols in foods and biological systems.
The SEEM: selective estrogen enzyme modulators in breast cancer.
The selective estrogen enzyme modulator (SEEM) in breast cancer.
The selective estrogen enzyme modulators in breast cancer: a review.
UDP-glucuronosyltransferase and sulfotransferase polymorphisms, sex hormone concentrations, and tumor receptor status in breast cancer patients.
Carcinogenesis
2-Acetylaminofluorene-mediated alteration in the level of liver arylsulfotransferase IV during rat hepatocarcinogenesis.
Aryl sulfotransferase IV deficiency in rat liver carcinogenesis initiated with diethylnitrosamine and promoted with N-2-fluorenylacetamide or its C-9-oxidized metabolites.
Detection and Quantification of Specific DNA Adducts by Liquid Chromatography-Tandem Mass Spectrometry in the Livers of Rats Given Estragole at the Carcinogenic Dose.
Hypomethylation of the rat aryl sulfotransferase IV gene and amplification of a DNA sequence during multistage 2-acetylaminofluorene hepatocarcinogenesis.
N-hydroxy-2-acetylaminofluorene sulfotransferase: its probable role in carcinogenesis and in protein-(methion-S-yl) binding in rat liver.
SULT1E1 inhibits cell proliferation and invasion by activating PPAR? in breast cancer.
The natural basil flavonoid nevadensin protects against a methyleugenol-induced marker of hepatocarcinogenicity in male F344 rat.
Carcinoma
All-trans retinoic acid induction of sulfotransferases.
Arsenic methylation capability, myeloperoxidase and sulfotransferase genetic polymorphisms, and the stage and grade of urothelial carcinoma.
Association of elevated sulfatides and sulfotransferase activities with human renal cell carcinoma.
Cancer-associated expression of glycolipid sulfotransferase gene in human renal cell carcinoma cells.
Elevated serum level of glycolipid sulfotransferase in patients with hepatocellular carcinoma.
Hepatocyte growth factor elevates the activity levels of glycolipid sulfotransferases in renal cell carcinoma cells.
Human uterine endometrial adenocarcinoma: characteristic acquirement of synthetic potentials for II3SO3-LacCer and ganglio series sulfoglycosphingolipids after transfer of the cancer cells to culture.
Inhibitory effects of sulfation inhibitors on initiation of pancreatic ductal carcinogenesis by N-nitrosobis(2-oxopropyl)amine in hamsters.
Potential tumor markers for human gastric cancer: an elevation of glycan:sulfotransferases and a concomitant loss of alpha1,2-fucosyltransferase activities.
Quantitative analysis of the association between sulfotransferase isoform 1A1 polymorphism and risk of urothelial carcinoma.
[Characterization of glycolipid sulfotransferase fractionated from rat kidney and involvement of the enzyme in human cancer]
Carcinoma, Hepatocellular
2-Acetylaminofluorene-mediated alteration in the level of liver arylsulfotransferase IV during rat hepatocarcinogenesis.
Basil extract inhibits the sulfotransferase mediated formation of DNA adducts of the procarcinogen 1'-hydroxyestragole by rat and human liver S9 homogenates and in HepG2 human hepatoma cells.
Characterization of a complementary DNA for rat liver aryl sulfotransferase IV and use in evaluating the hepatic gene transcript levels of rats at various stages of 2-acetylaminofluorene-induced hepatocarcinogenesis.
Development and application of test methods for the detection of dietary constituents which protect against heterocyclic aromatic amines.
Development of a competitive reverse-transcription polymerase chain reaction for quantitative measurement of sulfotransferase subfamily 1A enzyme in human hepatoma cells.
Dopamine-induced SULT1A3/4 promotes EMT and cancer stemness in hepatocellular carcinoma.
Down-regulation of dehydroepiandrosterone sulfotransferase gene in human hepatocellular carcinoma.
Hypomethylation of the rat aryl sulfotransferase IV gene and amplification of a DNA sequence during multistage 2-acetylaminofluorene hepatocarcinogenesis.
Inconsistent expression of glycolipid sulfotransferase activity between hepatoma and serum.
Investigation of the genotoxic effects of 2-amino-9H-pyrido[2,3-b]indole in different organs of rodents and in human derived cells.
LC-MS/MS quantification of sulfotransferases is better than conventional immunogenic methods in determining human liver SULT activities: implication in precision medicine.
[Characterization of glycolipid sulfotransferase fractionated from rat kidney and involvement of the enzyme in human cancer]
Carcinoma, Intraductal, Noninfiltrating
Expression of aromatase and estrogen sulfotransferase in preinvasive and invasive breast cancer.
Intracrinology of sex steroids in ductal carcinoma in situ (DCIS) of human breast: comparison to invasive ductal carcinoma (IDC) and non-neoplastic breast.
Carcinoma, Renal Cell
Association of elevated sulfatides and sulfotransferase activities with human renal cell carcinoma.
Cancer-associated expression of glycolipid sulfotransferase gene in human renal cell carcinoma cells.
Elevated serum level of glycolipid sulfotransferase in patients with hepatocellular carcinoma.
Hepatocyte growth factor elevates the activity levels of glycolipid sulfotransferases in renal cell carcinoma cells.
Sulfolipids and glycolipid sulfotransferase activities in human renal cell carcinoma cells.
[Characterization of glycolipid sulfotransferase fractionated from rat kidney and involvement of the enzyme in human cancer]
Carcinoma, Squamous Cell
Human uterine endometrial adenocarcinoma: characteristic acquirement of synthetic potentials for II3SO3-LacCer and ganglio series sulfoglycosphingolipids after transfer of the cancer cells to culture.
Cardiovascular Diseases
Metabolism, Protein Binding, and Renal Clearance of Microbiota-Derived p-Cresol in Patients with CKD.
Cerebral Infarction
Effect of the combination of astragaloside IV and Panax notoginseng saponins on pyroptosis and necroptosis in rat models of cerebral ischemia-reperfusion.
Chondrosarcoma
Epigenetics: methylation-associated repression of heparan sulfate 3-O-sulfotransferase gene expression contributes to the invasive phenotype of H-EMC-SS chondrosarcoma cells.
Choriocarcinoma
Human uterine endometrial adenocarcinoma: characteristic acquirement of synthetic potentials for II3SO3-LacCer and ganglio series sulfoglycosphingolipids after transfer of the cancer cells to culture.
Colonic Neoplasms
Metabolic differences and their impact on human disease Sulfotransferase and colorectal cancer.
Colorectal Neoplasms
A pharmacogenetic study to investigate the role of dietary carcinogens in the etiology of colorectal cancer.
Chemical Tumor Biology of Heparan Sulfate Proteoglycans.
Metabolic differences and their impact on human disease Sulfotransferase and colorectal cancer.
[A case-control study on the association between the genetic polymorphism of sulfotransferase 1A1, diet and susceptibility of colorectal cancer]
Communicable Diseases
Strategies for drug discovery by targeting sulfation pathways.
Congenital Abnormalities
Regulation of expression of the rodent cytosolic sulfotransferases.
Corneal Dystrophies, Hereditary
Measurement of activities of human serum sulfotransferases which transfer sulfate to the galactose residues of keratan sulfate and to the nonreducing end N-acetylglucosamine residues of N-acetyllactosamine trisaccharide: comparison between normal controls and patients with macular corneal dystrophy.
Serum sulfotransferase levels in patients with macular corneal dystrophy type I.
COVID-19
Relationships between hyperinsulinaemia, magnesium, vitamin D, thrombosis and COVID-19: rationale for clinical management.
Cystic Fibrosis
Regulation of hepatic sulfotransferase (SULT) 1E1 expression and effects on estrogenic activity in cystic fibrosis (CF).
Repression of CFTR activity in human MMNK-1 cholangiocytes induces sulfotransferase 1E1 expression in co-cultured HepG2 hepatocytes.
Dehydration
Crystallization of retinol dehydratase from Spodoptera frugiperda: improvement of crystal quality by modification by ethylmercurythiosalicylate.
Sungeidines from a Non-canonical Enediyne Biosynthetic Pathway.
Encephalopathy, Bovine Spongiform
Molecular analysis of carbohydrate N-acetylgalactosamine 4-O sulfotransferase 8 (CHST8) as a candidate gene for bovine spongiform encephalopathy susceptibility.
Endometrial Neoplasms
Aberrant pre-receptor regulation of estrogen and progesterone action in endometrial cancer.
Effective Selection of a Well-Differentiated Type of Human Uterine Endometrial Carcinoma Cells by Transfection of the Sulfotransferase Gene and Possible Association of Sulfoglycolipids With Well-Differentiated Phenotypes.
Estrogen productivity of endometrium and endometrial cancer tissue; influence of aromatase on proliferation of endometrial cancer cells.
Expression analysis of estrogen-metabolizing enzymes in human endometrial cancer.
SULT1E1 inhibits cell proliferation and invasion by activating PPAR? in breast cancer.
Endometriosis
AXIN1 in Plasma or Serum Is a Potential New Biomarker for Endometriosis.
Eosinophilia
Astragaloside IV attenuates allergic inflammation by regulation Th1/Th2 cytokine and enhancement CD4(+)CD25(+)Foxp3 T cells in ovalbumin-induced asthma.
Erectile Dysfunction
Sulfation of apomorphine by human sulfotransferases: evidence of a major role for the polymorphic phenol sulfotransferase, SULT1A1.
Exanthema
12-OH-nevirapine sulfate, formed in the skin, is responsible for nevirapine-induced skin rash.
Investigating the Mechanism of Trimethoprim-Induced Skin Rash and Liver Injury.
Nevirapine bioactivation and covalent binding in the skin.
Fatty Liver
Astragaloside IV inhibits protein tyrosine phosphatase 1B and improves insulin resistance in insulin-resistant HepG2 cells and triglyceride accumulation in oleic acid (OA)-treated HepG2 cells.
Gastritis
Sulfation of glycolipids by human gastric mucosa in disease.
Glioma
Effects of methyl mercury and triethyllead on Na+K+ATPase and pyruvate dehydrogenase activities in glioma C6 cells.
Herpes Simplex
Biosynthesis of 3-O-sulfated heparan sulfate: unique substrate specificity of heparan sulfate 3-O-sulfotransferase isoform 5.
Structural analysis of the sulfotransferase (3-o-sulfotransferase isoform 3) involved in the biosynthesis of an entry receptor for herpes simplex virus 1.
Sulfotransferase and Heparanase: Remodeling Engines in Promoting Virus Infection and Disease Development.
Zebrafish 3-O-Sulfotransferase-4 Generated Heparan Sulfate Mediates HSV-1 Entry and Spread.
Herpes Zoster
McCune-Albright Syndrome with Male Premature Pubarche of Unusual Origin.
Hirsutism
Androsterone sulfate: physiology and clinical significance in hirsute women.
Huntington Disease
Acetaminophen sulfation in patients with Parkinson's disease or Huntington's disease is not impaired.
Hyperthyroidism
Serum concentration of androstenediol and androstenediol sulfate in patients with hyperthyroidism and hypothyroidism.
Infections
Glycosylation-related gene expression profiling in brain and spleen of scrapie-affected mouse.
Molecular cloning of a sulfotransferase in Arabidopsis thaliana and regulation during development and in response to infection with pathogenic bacteria.
Insulin Resistance
Astragaloside IV inhibits protein tyrosine phosphatase 1B and improves insulin resistance in insulin-resistant HepG2 cells and triglyceride accumulation in oleic acid (OA)-treated HepG2 cells.
Regulation of expression of the rodent cytosolic sulfotransferases.
Intellectual Disability
Platelet abnormalities in aggressive subjects with mental deficiency.
Ischemic Stroke
Epistasis analysis for estrogen metabolic and signaling pathway genes on young ischemic stroke patients.
Joint Dislocations
Further delineation of CANT1 phenotypic spectrum and demonstration of its role in proteoglycan synthesis.
Kidney Neoplasms
Cancer-associated alternative usage of multiple promoters of human GalCer sulfotransferase gene.
Purification and characterization of 3'-phosphoadenosine-5'-phosphosulfate:GalCer sulfotransferase from human renal cancer cells.
Pyridoxal 5'-phosphate binds to a lysine residue in the adenosine 3'-phosphate 5'-phosphosulfate recognition site of glycolipid sulfotransferase from human renal cancer cells.
Regulation of activity levels of glycolipid sulfotransferases by transforming growth factor alpha in renal cell carcinoma cells.
[Studies on the regulation of glycolipid sulfotransferase activity in human renal cancer cells]
Leiomyoma
[Study on the local estrogen biosynthesis in human uterine leiomyoma]
Leukemia
Changes in heparan sulfate sulfotransferases and cell-surface heparan sulfate during SKM-1 cells granulocytic differentiation and A549 cells epithelial-mesenchymal transition.
Principal drug-metabolizing enzyme systems in L1210 leukemia sensitive or resistant to BCNU in vivo.
Leukemia, Lymphocytic, Chronic, B-Cell
Deregulation of the carbohydrate (chondroitin 4) sulfotransferase 11 (CHST11) gene in a B-cell chronic lymphocytic leukemia with a t(12;14)(q23;q32).
Liver Cirrhosis
Elevated serum level of glycolipid sulfotransferase in patients with hepatocellular carcinoma.
Liver Diseases
Altered UDP-glucuronosyltransferase and sulfotransferase expression and function during progressive stages of human nonalcoholic fatty liver disease.
Astragaloside IV inhibits protein tyrosine phosphatase 1B and improves insulin resistance in insulin-resistant HepG2 cells and triglyceride accumulation in oleic acid (OA)-treated HepG2 cells.
Downregulation of sulfotransferase expression and activity in diseased human livers.
Liver Neoplasms
2-Acetylaminofluorene-mediated alteration in the level of liver arylsulfotransferase IV during rat hepatocarcinogenesis.
Reaction product inactivation of aryl sulfotransferase IV following electrophilic substitution by the sulfuric acid ester of N-hydroxy-2-acetylaminofluorene.
Lung Neoplasms
Changes in heparan sulfate sulfotransferases and cell-surface heparan sulfate during SKM-1 cells granulocytic differentiation and A549 cells epithelial-mesenchymal transition.
Impact of polymorphism in sulfotransferase gene on the risk of lung cancer.
Sulfotransferase (SULT) 1A1 polymorphism as a predisposition factor for lung cancer: a case-control analysis.
Lymphatic Metastasis
Differential expression pattern of estrogen receptors, aromatase, and sulfotransferase in breast cancer tissue and corresponding lymph node metastases.
Mastocytoma
Functional analysis of conserved cysteines in heparan sulfate N-deacetylase-N-sulfotransferases.
Melanoma
Human Natural Killer-1 Sulfotransferase (HNK-1ST)-induced Sulfate Transfer Regulates Laminin-binding Glycans on ?-Dystroglycan.
Human uterine endometrial adenocarcinoma: characteristic acquirement of synthetic potentials for II3SO3-LacCer and ganglio series sulfoglycosphingolipids after transfer of the cancer cells to culture.
Melanoma Cell Adhesion and Migration Is Modulated by the Uronyl 2-O Sulfotransferase.
Myocardial Infarction
HIF-1? signaling activation by post-ischemia treatment with astragaloside IV attenuates myocardial ischemia-reperfusion injury.
Neoplasm Metastasis
Differential expression pattern of estrogen receptors, aromatase, and sulfotransferase in breast cancer tissue and corresponding lymph node metastases.
Mechanism of regulation and suppression of melanoma invasiveness by novel retinoic acid receptor-gamma target gene carbohydrate sulfotransferase 10.
Neoplasms
2-Acetylaminofluorene-mediated alteration in the level of liver arylsulfotransferase IV during rat hepatocarcinogenesis.
Aryl sulfotransferase IV deficiency in rat liver carcinogenesis initiated with diethylnitrosamine and promoted with N-2-fluorenylacetamide or its C-9-oxidized metabolites.
Changes in heparan sulfate sulfotransferases and cell-surface heparan sulfate during SKM-1 cells granulocytic differentiation and A549 cells epithelial-mesenchymal transition.
Characterization of a complementary DNA for rat liver aryl sulfotransferase IV and use in evaluating the hepatic gene transcript levels of rats at various stages of 2-acetylaminofluorene-induced hepatocarcinogenesis.
Chemical Tumor Biology of Heparan Sulfate Proteoglycans.
Comparison of mouse and human colon tumors with regard to phase I and phase II drug-metabolizing enzyme systems.
Cytochrome P450 (CYP) 1A2, sulfotransferase (SULT) 1A1, and N-acetyltransferase (NAT) 2 polymorphisms and susceptibility to urothelial cancer.
Dehydroepiandrosterone sulfotransferase as a possible shunt for the control of steroid metabolism in human mammary carcinoma.
Differential expression pattern of estrogen receptors, aromatase, and sulfotransferase in breast cancer tissue and corresponding lymph node metastases.
Discovery of Carbohydrate Sulfotransferase Inhibitors from a Kinase-Directed Library We thank Sharon Long and Dave Keating for providing both the NodH sulfotransferase and APS Kinase during our preliminary experiments and Jack Kirsch for numerous helpful conversations. J.I.A. and K.G.B were supported by NIH Molecular Biophysics Training Grant (No. T32GM0895). This research was funded by grants to C.R.B. from the Pew Scholars Program, the W. M. Keck Foundation and the American Cancer Society (Grant No. RPG9700501BE).
Distinctive glycolipid patterns in Wilms' tumor and renal cell carcinoma.
Effects of partial hepatectomy and dietary phenobarbital on liver and mammary tumorigenesis by two N-hydroxy-N-acylaminobiphenyls in female CD rats.
Estrogen-metabolizing gene polymorphisms in the assessment of female hormone-dependent cancer risk.
Expanding the view of breast cancer metabolism: Promising molecular targets and therapeutic opportunities.
Expression of aromatase and estrogen sulfotransferase in preinvasive and invasive breast cancer.
Expression of sulfotransferase SULT1A1 in cancer cells predicts susceptibility to the novel anticancer agent NSC-743380.
Feminization as a result of both peripheral conversion of androgens and direct estrogen production from an adrenocortical carcinoma.
Genetic polymorphism in the sulfotransferase SULT1A1 gene in cancer.
Human uterine endometrial adenocarcinoma: characteristic acquirement of synthetic potentials for II3SO3-LacCer and ganglio series sulfoglycosphingolipids after transfer of the cancer cells to culture.
Inflammatory cues modulate the expression of secretory product genes, Golgi sulfotransferases and sulfomucin production in LS174T cells.
Inhibition by pentachlorophenol of the initiating and promoting activities of 1'-hydroxysafrole for the formation of enzyme-altered foci and tumors in rat liver.
Malabaricone C-containing mace extract inhibits safrole bioactivation and DNA adduct formation both in vitro and in vivo.
Paclitaxel inhibits N-acetyltransferase activity and gene expression in human stomach tumor cells (SC-M1).
Phylogenomic approaches to common problems encountered in the analysis of low copy repeats: the sulfotransferase 1A gene family example.
Polymorphisms in hormone metabolism and growth factor genes and mammographic density in Norwegian postmenopausal hormone therapy users and non-users.
Principal xenobiotic-metabolizing enzyme systems in human head and neck squamous cell carcinoma.
Regulation of expression of the rodent cytosolic sulfotransferases.
Species differences of glucuronidation and sulfation in relation to hepatocarcinogenesis.
Strategies for drug discovery by targeting sulfation pathways.
Strong evidence from studies with brachymorphic mice and pentachlorophenol that 1'-sulfoöxysafrole is the major ultimate electrophilic and carcinogenic metabolite of 1'-hydroxysafrole in mouse liver.
Structure of a human carcinogen-converting enzyme, SULT1A1. Structural and kinetic implications of substrate inhibition.
Sulfolipids and glycolipid sulfotransferase activities in human renal cell carcinoma cells.
Sulfotransferase genetic variation: from cancer risk to treatment response.
Sulfotransferase SULT1A1 Arg213His polymorphism with cancer risk: a meta-analysis of 53 case-control studies.
Tandem mass spectrometry analysis of N2-(trans-Isoestragol-3'-yl)-2'-deoxyguanosine as a strategy to study species differences in sulfotransferase conversion of the proximate carcinogen 1'-hydroxyestragole.
The pattern of glycosyl- and sulfotransferase activities in cancer cell lines: a predictor of individual cancer-associated distinct carbohydrate structures for the structural identification of signature glycans.
UDP-glucuronosyltransferase and sulfotransferase polymorphisms, sex hormone concentrations, and tumor receptor status in breast cancer patients.
[Characterization of glycolipid sulfotransferase fractionated from rat kidney and involvement of the enzyme in human cancer]
Neuralgia
Regulation of the KATP-JNK gap junction signaling pathway by immunomodulator astragaloside IV attenuates neuropathic pain.
Neuroblastoma
Proteomic study of amyloid beta (25-35) peptide exposure to neuronal cells: Impact on APE1/Ref-1's protein-protein interaction.
Neurodegenerative Diseases
Sulfotransferase 1A3/4 copy number variation is associated with neurodegenerative disease.
Neuronal Ceroid-Lipofuscinoses
Chromosome 16 microdeletion in a patient with juvenile neuronal ceroid lipofuscinosis (Batten disease).
Non-alcoholic Fatty Liver Disease
Altered UDP-glucuronosyltransferase and sulfotransferase expression and function during progressive stages of human nonalcoholic fatty liver disease.
Astragaloside IV inhibits protein tyrosine phosphatase 1B and improves insulin resistance in insulin-resistant HepG2 cells and triglyceride accumulation in oleic acid (OA)-treated HepG2 cells.
Obesity
Analyses of shared genetic factors between asthma and obesity in children.
Drug-metabolizing enzyme and transporter expression in a mouse model of diabetes and obesity.
Osteochondrodysplasias
Further delineation of CANT1 phenotypic spectrum and demonstration of its role in proteoglycan synthesis.
Spondyloepiphyseal dysplasia, chondroitin sulfate type: a possible defect of PAPS--chondroitin sulfate sulfotransferase in humans.
Osteosarcoma
Estradiol-17beta sulfotransferase activity in canine osteosarcoma D17 cells.
Parkinson Disease
Acetaminophen sulfation in patients with Parkinson's disease or Huntington's disease is not impaired.
Sulfation of apomorphine by human sulfotransferases: evidence of a major role for the polymorphic phenol sulfotransferase, SULT1A1.
Pheochromocytoma
Proteomic study of amyloid beta (25-35) peptide exposure to neuronal cells: Impact on APE1/Ref-1's protein-protein interaction.
Phyllodes Tumor
Selective spatial upregulation of intratumoral stromal aromatase in breast cancer patients: evidence for imbalance of local estrogen metabolism.
Polycystic Kidney Diseases
Decreased sulfotransferase SULT1C2 gene expression in DPT-induced polycystic kidney.
Polycystic Ovary Syndrome
Effect of insulin and testosterone on androgen production and transcription of SULT2A1 in the NCI-h295r adrenocortical cell line.
Prostatic Neoplasms
Androgen deprivation by activating the liver X receptor.
Inhibitory Interplay of SULT2B1b Sulfotransferase with AKR1C3 Aldo-keto Reductase in Prostate Cancer.
SULT2B1b sulfotransferase: induction by vitamin D receptor and reduced expression in prostate cancer.
TNF? enhances the motility and invasiveness of prostatic cancer cells by stimulating the expression of selective glycosyl- and sulfotransferase genes involved in the synthesis of selectin ligands.
Pulmonary Disease, Chronic Obstructive
Increased levels of enzymes involved in local estradiol synthesis in chronic obstructive pulmonary disease.
Rhinitis, Allergic
miR-487b mitigates allergic rhinitis through inhibition of the IL-33/ST2 signaling pathway.
Sarcoma
Human uterine endometrial adenocarcinoma: characteristic acquirement of synthetic potentials for II3SO3-LacCer and ganglio series sulfoglycosphingolipids after transfer of the cancer cells to culture.
Potential tumor markers for human gastric cancer: an elevation of glycan:sulfotransferases and a concomitant loss of alpha1,2-fucosyltransferase activities.
Seizures
Elevated sulfatide levels in neurons causes lethal audiogenic seizures in mice.
Sepsis
Astragaloside IV attenuates inflammatory reaction via activating immune function of regulatory T-cells inhibited by HMGB1 in mice.
Sleep Deprivation
Gene expression in the brain across the sleep-waking cycle.
Spinal Cord Injuries
The Adhesion Molecule-Characteristic HNK-1 Carbohydrate Contributes to Functional Recovery After Spinal Cord Injury in Adult Zebrafish.
Starvation
[Effect of starvation and acetone on the enzyme systems of biotransformation and toxicity of xenobiotics--CYP2E1 substrates in rats]
Stomach Diseases
Sulfation of glycolipids by human gastric mucosa in disease.
Stomach Neoplasms
Sulfation of glycolipids by human gastric mucosa in disease.
Stomach Ulcer
Sulfation of glycolipids by human gastric mucosa in disease.
Thymoma
Sulfated syndecan 1 is critical to preventing cellular senescence by modulating fibroblast growth factor receptor endocytosis.
Tuberculosis
Biotransformation and bioactivation reactions - 2015 literature highlights.
Molecular cloning and expression of a novel glycolipid sulfotransferase in Mycobacterium tuberculosis.
Overproduction, purification and preliminary X-ray diffraction analysis of a sulfotransferase from Mycobacterium tuberculosis H37Rv.
tyrosine-ester sulfotransferase deficiency
Aryl sulfotransferase IV deficiency in rat liver carcinogenesis initiated with diethylnitrosamine and promoted with N-2-fluorenylacetamide or its C-9-oxidized metabolites.
Upregulation of UGT2B4 Expression by 3'-Phosphoadenosine-5'-Phosphosulfate Synthase Knockdown: Implications for Coordinated Control of Bile Acid Conjugation.
Urinary Bladder Neoplasms
Polymorphisms for aromatic amine metabolism in humans: relevance for human carcinogenesis.
Virus Diseases
Sulfotransferase and Heparanase: Remodeling Engines in Promoting Virus Infection and Disease Development.
Wilms Tumor
[Characterization of glycolipid sulfotransferase fractionated from rat kidney and involvement of the enzyme in human cancer]
[Glycolipid alterations in human kidney carcinoma]