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Disease on EC 2.8.2.15 - steroid sulfotransferase

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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
3alpha(or 20beta)-hydroxysteroid dehydrogenase deficiency
Premature adrenarche: novel lessons from early onset androgen excess.
Adenocarcinoma
Cholesterol Sulfonation Enzyme, SULT2B1b, Modulates AR and Cell Growth Properties in Prostate Cancer.
Cloning and expression of cDNA encoding human placental estrogen sulfotransferase.
Inhibition of SULT2B1b expression alters effects of 3beta-hydroxysteroids on cell proliferation and steroid hormone receptor expression in human LNCaP prostate cancer cells.
Sulfotransferase 2B1b in human breast: differences in subcellular localization in African American and Caucasian women.
Adenoma
Genetic and Histopathologic Inter-Tumor Heterogeneity in Primary Aldosteronism.
Immunolocalization of dehydroepiandrosterone sulfotransferase in normal and pathologic human adrenal gland.
Adrenocortical Adenoma
Immunolocalization of dehydroepiandrosterone sulfotransferase in normal and pathologic human adrenal gland.
Adrenocortical Carcinoma
Immunolocalization of dehydroepiandrosterone sulfotransferase in normal and pathologic human adrenal gland.
Atherosclerosis
Reduced SULT2B1b expression alleviates ox-LDL-induced inflammation by upregulating miR-148-3P via inhibiting the IKK?/NF-?B pathway in macrophages.
Breast Neoplasms
Different subcellular localization of sulphotransferase 2B1b in human placenta and prostate.
Endocrine steroid sulfotransferases: steroid alcohol sulfotransferase from human breast carcinoma cell line MCF-7.
Enzymatic Inactivation of Oxysterols in Breast Tumor Cells Constraints Metastasis Formation by Reprogramming the Metastatic Lung Microenvironment.
Genetics of androgen metabolism in women with infertility and hypoandrogenism.
High metabolization of catecholestrogens by type 1 estrogen sulfotransferase (hEST1).
Relationship between intratumoral expression of genes coding for xenobiotic-metabolizing enzymes and benefit from adjuvant tamoxifen in estrogen receptor alpha-positive postmenopausal breast carcinoma.
The steroid alcohol and estrogen sulfotransferases in rodent and human mammary tumors.
Carcinogenesis
Hydroxysteroid sulfotransferase 2B1 affects gastric epithelial function and carcinogenesis induced by a carcinogenic agent.
Carcinoma
Different subcellular localization of sulphotransferase 2B1b in human placenta and prostate.
Immunolocalization of dehydroepiandrosterone sulfotransferase in normal and pathologic human adrenal gland.
Overexpression of steroid sulfotransferase genes is associated with worsened prognosis and with immune exclusion in clear cell-renal cell carcinoma.
Carcinoma, Hepatocellular
Down-regulation of dehydroepiandrosterone sulfotransferase gene in human hepatocellular carcinoma.
Hydroxysteroid sulfotransferase SULT2B1b promotes hepatocellular carcinoma cells proliferation in vitro and in vivo.
Overexpression of SULT2B1b Promotes Angiogenesis in Human Gastric Cancer.
Cholangiocarcinoma
Progenitor-derived hepatocyte-like (B-13/H) cells metabolise 1'-hydroxyestragole to a genotoxic species via a SULT2B1-dependent mechanism.
Choriocarcinoma
Characterization of Proline-Serine-Rich Carboxyl Terminus in Human Sulfotransferase 2B1b: Immunogenicity, Subcellular Localization, Kinetic Properties, and Phosphorylation.
Human cytosolic sulfotransferase 2B1: isoform expression, tissue specificity and subcellular localization.
Colorectal Neoplasms
Association study of genetic variants in estrogen metabolic pathway genes and colorectal cancer risk and survival.
Overexpression of SULT2B1b is an independent prognostic indicator and promotes cell growth and invasion in colorectal carcinoma.
Communicable Diseases
Influenza A virus infection activates cholesterol sulfotransferase (SULT2B1b) in the lung of female C57BL/6 mice.
COVID-19
Relationships between hyperinsulinaemia, magnesium, vitamin D, thrombosis and COVID-19: rationale for clinical management.
Cushing Syndrome
Serum levels of dehydroepiandrosterone sulfate in patients with asymptomatic cortisol producing adrenal adenoma: comparison with adrenal Cushing's syndrome and non-functional adrenal tumor.
Endometrial Neoplasms
Disturbed expression of phase I and phase II estrogen-metabolizing enzymes in endometrial cancer: Lower levels of CYP1B1 and increased expression of S-COMT.
Fatty Liver
Inhibition of LXR signaling by SULT2B1b promotes liver regeneration after partial hepatectomy in mouse models of nonalcoholic fatty liver disease.
Glioblastoma
Hydroxysteroid sulfotransferase 2B1b expression and localization in normal human brain.
Glioma
Regulation of SULT2B1a (pregnenolone sulfotransferase) expression in rat C6 glioma cells: relevance of AMPA receptor-mediated NO signaling.
Hepatitis, Chronic
17Beta-hydroxysteroid dehydrogenase type 2 and dehydroepiandrosterone sulfotransferase in the human liver.
Herpes Zoster
Age-dependent increases in adrenal cytochrome b5 and serum 5-androstenediol-3-sulfate.
Dehydroepiandrosterone and dehydroepiandrosterone sulfate production in the human adrenal during development and aging.
Developmental changes in steroidogenic enzymes in human postnatal adrenal cortex: immunohistochemical studies.
Genetic and Histopathologic Inter-Tumor Heterogeneity in Primary Aldosteronism.
Human dehydroepiandrosterone sulfotransferase. Purification, molecular cloning, and characterization.
Immunolocalization of dehydroepiandrosterone sulfotransferase in normal and pathologic human adrenal gland.
Hyperlipidemias
Oxysterol sulfation by cytosolic sulfotransferase suppresses liver X receptor/sterol regulatory element binding protein-1c signaling pathway and reduces serum and hepatic lipids in mouse models of nonalcoholic fatty liver disease.
Hyperthyroidism
Serum dehydroepiandrosterone, dehydroepiandrosterone sulfate, and pregnenolone sulfate concentrations in patients with hyperthyroidism and hypothyroidism.
Ichthyosis
Mutations in SULT2B1 Cause Autosomal-Recessive Congenital Ichthyosis in Humans.
Novel Homozygous Mutations in the Genes TGM1, SULT2B1, SPINK5 and FLG in Four Families Underlying Congenital Ichthyosis.
Infections
Oxysterol sulfation by cytosolic sulfotransferase suppresses liver X receptor/sterol regulatory element binding protein-1c signaling pathway and reduces serum and hepatic lipids in mouse models of nonalcoholic fatty liver disease.
Influenza, Human
Influenza A virus infection activates cholesterol sulfotransferase (SULT2B1b) in the lung of female C57BL/6 mice.
Intellectual Disability
Genetics of androgen metabolism in women with infertility and hypoandrogenism.
Liver Diseases
Inhibition of LXR signaling by SULT2B1b promotes liver regeneration after partial hepatectomy in mouse models of nonalcoholic fatty liver disease.
Lymphatic Metastasis
Overexpression of SULT2B1b is an independent prognostic indicator and promotes cell growth and invasion in colorectal carcinoma.
Neoplasm Metastasis
Overexpression of SULT2B1b is an independent prognostic indicator and promotes cell growth and invasion in colorectal carcinoma.
Neoplasms
Association study of genetic variants in estrogen metabolic pathway genes and colorectal cancer risk and survival.
Cholesterol Sulfonation Enzyme, SULT2B1b, Modulates AR and Cell Growth Properties in Prostate Cancer.
Dehydroepiandrosterone sulfotransferase as a possible shunt for the control of steroid metabolism in human mammary carcinoma.
Distinct expression patterns of SULT2B1b in human prostate epithelium.
Hydroxysteroid sulfotransferase SULT2B1b promotes hepatocellular carcinoma cells proliferation in vitro and in vivo.
Intratumoral heterogeneity of the tumor cells based on in situ cortisol excess in cortisol-producing adenomas; ?An association among morphometry, genotype and cellular senescence?.
Involvement of prostaglandin E2 in the tumor promoter phorbol ester-caused increase in epidermal cholesterol sulfotransferase activity.
Overexpression of SULT2B1b is an independent prognostic indicator and promotes cell growth and invasion in colorectal carcinoma.
Overexpression of SULT2B1b Promotes Angiogenesis in Human Gastric Cancer.
Quantitative Secretomic Analysis Identifies Extracellular Protein Factors That Modulate the Metastatic Phenotype of Non-Small Cell Lung Cancer.
The steroid alcohol and estrogen sulfotransferases in rodent and human mammary tumors.
Tumor Necrosis Factor-Alpha-Nuclear Factor-Kappa B-Signaling Enhances St2b2 Expression during 12-O-Tetradecanoylphorbol-13-acetate-Induced Epidermal Hyperplasia.
Tumor-mediated liver X receptor-alpha activation inhibits CC chemokine receptor-7 expression on dendritic cells and dampens antitumor responses.
Non-alcoholic Fatty Liver Disease
Inhibition of LXR signaling by SULT2B1b promotes liver regeneration after partial hepatectomy in mouse models of nonalcoholic fatty liver disease.
Obesity
Cholesterol sulfate and cholesterol sulfotransferase inhibit gluconeogenesis by targeting hepatocyte nuclear factor 4?.
Obesity genes and diabetes induction in the mouse.
Prostatic Intraepithelial Neoplasia
Cholesterol Sulfonation Enzyme, SULT2B1b, Modulates AR and Cell Growth Properties in Prostate Cancer.
Prostatic Neoplasms
Cholesterol Sulfonation Enzyme, SULT2B1b, Modulates AR and Cell Growth Properties in Prostate Cancer.
Cholesterol Sulfotransferase SULT2B1b Modulates Sensitivity to Death Receptor Ligand TNF? in Castration-Resistant Prostate Cancer.
Different subcellular localization of sulphotransferase 2B1b in human placenta and prostate.
Distinct expression patterns of SULT2B1b in human prostate epithelium.
Inhibition of SULT2B1b expression alters effects of 3beta-hydroxysteroids on cell proliferation and steroid hormone receptor expression in human LNCaP prostate cancer cells.
Inhibitory Interplay of SULT2B1b Sulfotransferase with AKR1C3 Aldo-keto Reductase in Prostate Cancer.
SULT2B1b sulfotransferase: induction by vitamin D receptor and reduced expression in prostate cancer.
Vitamin D in Prostate Cancer.
Sepsis
Dissociation of serum dehydroepiandrosterone and dehydroepiandrosterone sulfate in septic shock.
Squamous Cell Carcinoma of Head and Neck
Inhibition of growth and squamous-cell differentiation markers in cultured human head and neck squamous carcinoma cells by beta-all-trans retinoic acid.
steroid sulfotransferase deficiency
Premature adrenarche: novel lessons from early onset androgen excess.
Stomach Neoplasms
Overexpression of SULT2B1b Promotes Angiogenesis in Human Gastric Cancer.
Uterine Cervical Neoplasms
Verteporfin Promotes the Apoptosis and Inhibits the Proliferation, Migration, and Invasion of Cervical Cancer Cells by Downregulating SULT2B1 Expression.
Viremia
Genetic variations in humans associated with differences in the course of hepatitis C.
Virus Diseases
Influenza A virus infection activates cholesterol sulfotransferase (SULT2B1b) in the lung of female C57BL/6 mice.