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Information on EC 2.7.8.33 - UDP-N-acetylglucosamine-undecaprenyl-phosphate N-acetylglucosaminephosphotransferase

for references in articles please use BRENDA:EC2.7.8.33
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IUBMB Comments
This enzyme catalyses the synthesis of N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol, an essential lipid intermediate for the biosynthesis of various bacterial cell envelope components. The enzyme also initiates the biosynthesis of enterobacterial common antigen and O-antigen lipopolysaccharide in certain Escherichia coli strains, including K-12 and of teichoic acid in certain Gram-positive bacteria .
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The expected taxonomic range for this enzyme is: Bacteria, Eukaryota
Synonyms
weca transferase, glcnac-p-p-und synthase, undecaprenyl-phosphate-glcnac-1-phosphate transferase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
UDP-N-acetyl-alpha-D-glucosamine + ditrans,octacis-undecaprenyl phosphate = UMP + N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol
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