Any feedback?
Please rate this page
(enzyme.php)
(0/150)

BRENDA support

Reference on EC 2.7.7.14 - ethanolamine-phosphate cytidylyltransferase

Please use the Reference Search for a specific query.
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Sundler, R.
Ethanolaminephosphate cytidylyltransferase. Purification and characterization of the enzyme from rat liver
J. Biol. Chem.
250
8585-8590
1975
Rattus norvegicus
Manually annotated by BRENDA team
Visedo-Gonzalez, E.; Dixon, H.B.F.
2-Aminoethylarsonic acid as an analogue of ethanolamine phosphate. Endowment of ethanolamine-phosphate cytidylyltransferase with CTP pyrophosphatase activity
Biochem. J.
260
299-301
1989
Rattus norvegicus
Manually annotated by BRENDA team
Kunishita, T.; Ledeen, R.W.
Phospholipid biosynthesis in myelin: presence of CTP:phosphoethanolamine cytidylyltransferase in purified myelin of rat brain
J. Neurochem.
42
326-333
1984
Rattus norvegicus
Manually annotated by BRENDA team
Plantavid, M.; Maget-Dana, R.; Douste-Blazy, L.
Interactions of phosphorylethanolamine analogs with phosphorylethanolamine-citidylyltransferase
Biochimie
57
951-957
1975
Rattus norvegicus
Manually annotated by BRENDA team
Vermeulen, P.S.; Tijburg, L.B.M.; Geelen, M.J.H.; van Golde, L.M.G.
Immunological characterization, lipid dependence, and subcellular localization of CTP:phosphoethanolamine cytidylyltransferase purified from rat liver. Comparison with CTP:phosphocholine cytidylyltransferase
J. Biol. Chem.
268
7458-7464
1993
Rattus norvegicus
Manually annotated by BRENDA team
Tijburg, L.B.M.; Vermeulen, P.S.; van Golde, L.M.G.
Ethanolamine-phosphate cytidylyltransferase
Methods Enzymol.
209
258-263
1992
Rattus norvegicus
Manually annotated by BRENDA team
Vermeulen, P.S.; Geelen, M.J.H.; van Golde, L.M.G.
Substrate specificity of CTP: phosphoethanolamine cytidylyltransferase purified from rat liver
Biochim. Biophys. Acta
1211
343-349
1994
Rattus norvegicus
Manually annotated by BRENDA team
Gasull, T.; Sarri, E.; DeGregorio-Rocasolano, N.; Trullas, R.
NMDA receptor overactivation inhibits phospholipid synthesis by decreasing choline-ethanolamine phosphotransferase activity
J. Neurosci.
23
4100-4107
2003
Rattus norvegicus
Manually annotated by BRENDA team
Bleijerveld, O.B.; Klein, W.; Vaandrager, A.B.; Helms, J.B.; Houweling, M.
Control of the CDPethanolamine pathway in mammalian cells: effect of CTP:phosphoethanolamine cytidylyltransferase overexpression and the amount of intracellular diacylglycerol
Biochem. J.
379
711-719
2004
Rattus norvegicus
Manually annotated by BRENDA team
Yang, W.; Mason, C.B.; Pollock, S.V.; Lavezzi, T.; Moroney, J.V.; Moore, T.S.
Membrane lipid biosynthesis in Chlamydomonas reinhardtii: expression and characterization of CTP:phosphoethanolamine cytidylyltransferase
Biochem. J.
382
51-57
2004
Chlamydomonas reinhardtii (Q84JV7), Chlamydomonas reinhardtii
Manually annotated by BRENDA team
Ohtsuka, J.; Nagata, K.; Lee, W.C.; Ono, Y.; Fukuda, R.; Ohta, A.; Tanokura, M.
Crystallization and preliminary X-ray analysis of CTP:phosphoethanolamine cytidylyltransferase (ECT) from Saccharomyces cerevisiae
Acta Crystallogr. Sect. F
62
1003-1005
2006
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Bakovic, M.; Fullerton, M.D.; Michel, V.
Metabolic and molecular aspects of ethanolamine phospholipid biosynthesis: the role of CTP:phosphoethanolamine cytidylyltransferase (Pcyt2)
Biochem. Cell Biol.
85
283-300
2007
Saccharomyces cerevisiae, Homo sapiens, Rattus norvegicus, Mus musculus (Q922E4), Mus musculus
Manually annotated by BRENDA team
Fullerton, M.D.; Hakimuddin, F.; Bakovic, M.
Developmental and metabolic effects of disruption of the mouse CTP:phosphoethanolamine cytidylyltransferase gene (Pcyt2)
Mol. Cell. Biol.
27
3327-3336
2007
Mus musculus
Manually annotated by BRENDA team
Mizoi, J.; Nakamura, M.; Nishida, I.
Defects in CTP:phosphorylethanolamine cytidylyltransferase affect embryonic and postembryonic development in Arabidopsis
Plant Cell
18
3370-3385
2006
Arabidopsis thaliana
Manually annotated by BRENDA team
Signorell, A.; Jelk, J.; Rauch, M.; Buetikofer, P.
Phosphatidylethanolamine is the precursor of the ethanolamine phosphoglycerol moiety bound to eukaryotic elongation factor 1A
J. Biol. Chem.
283
20320-20329
2008
Trypanosoma brucei
Manually annotated by BRENDA team
Tie, A.; Bakovic, M.
Alternative splicing of CTP:phosphoethanolamine cytidylyltransferase produces two isoforms that differ in catalytic properties
J. Lipid Res.
48
2172-2181
2007
Mus musculus (Q922E4), Mus musculus
Manually annotated by BRENDA team
Zhu, L.; Johnson, C.; Bakovic, M.
Stimulation of the human CTP:phosphoethanolamine cytidylyltransferase gene by early growth response protein 1
J. Lipid Res.
49
2197-2211
2008
Homo sapiens
Manually annotated by BRENDA team
Ando, H.; Horibata, Y.; Yamashita, S.; Oyama, T.; Sugimoto, H.
Low-density lipoprotein and oxysterols suppress the transcription of CTP:Phosphoethanolamine cytidylyltransferase in vitro
Biochim. Biophys. Acta
1801
487-495
2010
Homo sapiens, Mus musculus
Manually annotated by BRENDA team
Zhu, L.; Michel, V.; Bakovic, M.
Regulation of the mouse CTP: phosphoethanolamine cytidylyltransferase gene Pcyt2 during myogenesis
Gene
447
51-59
2009
Mus musculus
Manually annotated by BRENDA team
Fullerton, M.D.; Hakimuddin, F.; Bonen, A.; Bakovic, M.
The development of a metabolic disease phenotype in CTP:phosphoethanolamine cytidylyltransferase-deficient mice
J. Biol. Chem.
284
25704-25713
2009
Mus musculus
Manually annotated by BRENDA team
Leonardi, R.; Frank, M.W.; Jackson, P.D.; Rock, C.O.; Jackowski, S.
Elimination of the CDP-ethanolamine pathway disrupts hepatic lipid homeostasis
J. Biol. Chem.
284
27077-27089
2009
Mus musculus
Manually annotated by BRENDA team
Gibellini, F.; Hunter, W.N.; Smith, T.K.
The ethanolamine branch of the Kennedy pathway is essential in the bloodstream form of Trypanosoma brucei
Mol. Microbiol.
73
826-843
2009
Trypanosoma brucei (B9WNA0), Trypanosoma brucei
Manually annotated by BRENDA team
Zhu, L.; Bakovic, M.
Breast cancer cells adapt to metabolic stress by increasing ethanolamine phospholipid synthesis and CTP:ethanolaminephosphate cytidylyltransferase-Pcyt2 activity
Biochem. Cell Biol.
90
188-199
2012
Homo sapiens
Manually annotated by BRENDA team
Maheshwari, S.; Lavigne, M.; Contet, A.; Alberge, B.; Pihan, E.; Kocken, C.; Wengelnik, K.; Douguet, D.; Vial, H.; Cerdan, R.
Biochemical characterization of Plasmodium falciparum CTP:phosphoethanolamine cytidylyltransferase shows that only one of the two cytidylyltransferase domains is active
Biochem. J.
450
159-167
2013
Plasmodium falciparum (Q8IDM2), Plasmodium falciparum
Manually annotated by BRENDA team
Pavlovic, Z.; Bakovic, M.
Regulation of phosphatidylethanolamine homeostasis - the critical role of CTP:phosphoethanolamine cytidylyltransferase (Pcyt2)
Int. J. Mol. Sci.
14
2529-2550
2013
Homo sapiens, Mus musculus, Mus musculus C57BL/6, Plasmodium berghei, Rattus norvegicus, Rattus norvegicus Wistar, Saccharomyces cerevisiae, Trypanosoma brucei
Manually annotated by BRENDA team
Tian, S.; Ohtsuka, J.; Wang, S.; Nagata, K.; Tanokura, M.; Ohta, A.; Horiuchi, H.; Fukuda, R.
Human CTP:phosphoethanolamine cytidylyltransferase: enzymatic properties and unequal catalytic roles of CTP-binding motifs in two cytidylyltransferase domains
Biochem. Biophys. Res. Commun.
449
26-31
2014
Homo sapiens (Q99447), Homo sapiens
Manually annotated by BRENDA team
Ando, H.; Aoyama, C.; Horibata, Y.; Satou, M.; Mitsuhashi, S.; Itoh, M.; Hosaka, K.; Sugimoto, H.
Transcriptional suppression of CTP:phosphoethanolamine cytidylyltransferase by 25-hydroxycholesterol is mediated by nuclear factor-Y and Yin Yang 1
Biochem. J.
471
369-379
2015
Mus musculus
Manually annotated by BRENDA team
Pavlovic, Z.; Singh, R.K.; Bakovic, M.
A novel murine CTP:phosphoethanolamine cytidylyltransferase splice variant is a post-translational repressor and an indicator that both cytidylyltransferase domains are required for activity
Gene
543
58-68
2014
Mus musculus (Q540F5), Mus musculus
Manually annotated by BRENDA team
Pavlovic, Z.; Zhu, L.; Pereira, L.; Singh, R.; Cornel, R.; Bakovic, M.
Isoform-specific and protein kinase C-mediated regulation of CTP:phosphoethanolamine cytidylyltransferase phosphorylation
J. Biol. Chem.
289
9053-9064
2014
Homo sapiens (Q99447), Homo sapiens
Manually annotated by BRENDA team
Susila, H.; Nasim, Z.; Gawarecka, K.; Jung, J.Y.; Jin, S.; Youn, G.; Ahn, J.H.
Phosphorylethanolamine cytidyltransferase 1 modulates flowering in a florigen-independent manner by regulating SVP
Development
148
dev193870
2020
Arabidopsis thaliana (Q9ZVI9), Arabidopsis thaliana
Manually annotated by BRENDA team
Ando, H.; Horibata, Y.; Aoyama, C.; Shimizu, H.; Shinohara, Y.; Yamashita, S.; Sugimoto, H.
Side-chain oxysterols suppress the transcription of CTP phosphoethanolamine cytidylyltransferase and 3-hydroxy-3-methylglutaryl-CoA reductase by inhibiting the interaction of p300 and NF-Y, and H3K27 acetylation
J. Steroid Biochem. Mol. Biol.
195
105482
2019
Mus musculus (Q922E4), Homo sapiens (Q99447)
Manually annotated by BRENDA team