Reference on EC 2.7.4.22 - UMP kinase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Labesse, G.; Bucurenci, N.; Douguet, D.; Sakamoto, H.; Landais, S.; Gagyi, C.; Gilles, A.M.; Barzu, O.
Comparative modelling and immunochemical reactivity of Escherichia coli UMP kinase
Biochem. Biophys. Res. Commun.
294
173-179
2002
Escherichia coli (P0A7E9), Escherichia coli
Fassy, F.; Krebs, O.; Lowinski, M.; Ferrari, P.; Winter, J.; Collard-Dutilleul, V.; Salahbey Hocini, K.
UMP kinase from Streptococcus pneumoniae: evidence for co-operative ATP binding and allosteric regulation
Biochem. J.
384
619-627
2004
Streptococcus pneumoniae (Q97R83), Streptococcus pneumoniae
Serina, L.; Blondin, C.; Krin, E.; Sismeiro, O.; Danchin, A.; Sakamoto, H.; Gilles, A.M.; Barzu, O.
Escherichia coli UMP-kinase, a member of the aspartokinase family, is a hexamer regulated by guanine nucleotides and UTP
Biochemistry
34
5066-5074
1995
Escherichia coli (P0A7E9), Escherichia coli
Serina, L.; Bucurenci, N.; Gilles, A.M.; Surewicz, W.K.; Fabian, H.; Mantsch, H.H.; Takahashi, M.; Petrescu, I.; Batelier, G.; Barzu, O.
Structural properties of UMP-kinase from Escherichia coli: modulation of protein solubility by pH and UTP
Biochemistry
35
7003-7011
1996
Escherichia coli (P0A7E9), Escherichia coli
Gagyi, C.; Bucurenci, N.; Sirbu, O.; Labesse, G.; Ionescu, M.; Ofiteru, A.; Assairi, L.; Landais, S.; Danchin, A.; Barzu, O.; Gilles, A.M.
UMP kinase from the Gram-positive bacterium Bacillus subtilis is strongly dependent on GTP for optimal activity
Eur. J. Biochem.
270
3196-3204
2003
Bacillus subtilis (O31749), Bacillus subtilis, Escherichia coli (P0A7E9), Escherichia coli
Bucurenci, N.; Serina, L.; Zaharia, C.; Landais, S.; Danchin, A.; Barzu, O.
Mutational analysis of UMP kinase from Escherichia coli
J. Bacteriol.
180
473-477
1998
Escherichia coli (P0A7E9), Escherichia coli
Landais, S.; Gounon, P.; Laurent-Winter, C.; Mazie, J.C.; Danchin, A.; Barzu, O.; Sakamoto, H.
Immunochemical analysis of UMP kinase from Escherichia coli
J. Bacteriol.
181
833-840
1999
Escherichia coli (P0A7E9), Escherichia coli
Ingraham, J.L.; Neuhard, J.
Cold-sensitive mutants of Salmonella typhimurium defective in uridine monophosphate kinase (pyrH)
J. Biol. Chem.
247
6259-6265
1972
Salmonella enterica subsp. enterica serovar Typhimurium (P65933), Salmonella enterica subsp. enterica serovar Typhimurium, Salmonella enterica subsp. enterica serovar Typhimurium JL1220 (P65933), Salmonella enterica subsp. enterica serovar Typhimurium JL1269 (P65933), Salmonella enterica subsp. enterica serovar Typhimurium JL1019 (P65933), Salmonella enterica subsp. enterica serovar Typhimurium JL1219 (P65933), Salmonella enterica subsp. enterica serovar Typhimurium KP1217 (P65933)
Briozzo, P.; Evrin, C.; Meyer, P.; Assairi, L.; Joly, N.; Barzu, O.; Gilles, A.M.
Structure of Escherichia coli UMP kinase differs from that of other nucleoside monophosphate kinases and sheds new light on enzyme regulation
J. Biol. Chem.
280
25533-25540
2005
Escherichia coli (P0A7E9), Escherichia coli
Marco-Marn, C.; Gil-Ortiz, F.; Rubio, V.
The crystal structure of Pyrococcus furiosus UMP kinase provides insight into catalysis and regulation in microbial pyrimidine nucleotide biosynthesis
J. Mol. Biol.
352
438-454
2005
Pyrococcus furiosus (Q8U122), Pyrococcus furiosus
Sakamoto, H.; Landais, S.; Evrin, C.; Laurent-Winter, C.; Barzu, O.; Kelln, R.A.
Structure-function relationships of UMP kinases from pyrH mutants of Gram-negative bacteria
Microbiology
150
2153-2159
2004
Escherichia coli (P0A7E9), Salmonella enterica subsp. enterica serovar Typhimurium (P65933)
Tu, J.L.; Chin, K.H.; Wang, A.H.; Chou, S.H.
The crystallization of apo-form UMP kinase from Xanthomonas campestris is significantly improved in a strong magnetic field
Acta Crystallogr. Sect. F
63
438-442
2007
Xanthomonas campestris, Xanthomonas campestris pv. campestris, Xanthomonas campestris pv. campestris 17
Jensen, K.S.; Johansson, E.; Jensen, K.F.
Structural and enzymatic investigation of the Sulfolobus solfataricus uridylate kinase shows competitive UTP inhibition and the lack of GTP stimulation
Biochemistry
46
2745-2757
2007
Saccharolobus solfataricus, Saccharolobus solfataricus (Q97ZE2)
Lee, S.E.; Kim, S.Y.; Kim, C.M.; Kim, M.K.; Kim, Y.R.; Jeong, K.; Ryu, H.J.; Lee, Y.S.; Chung, S.S.; Choy, H.E.; Rhee, J.H.
The pyrH gene of Vibrio vulnificus is an essential in vivo survival factor
Infect. Immun.
75
2795-2801
2007
Vibrio vulnificus, Vibrio vulnificus MO6-24/O
Evrin, C.; Straut, M.; Slavova-Azmanova, N.; Bucurenci, N.; Onu, A.; Assairi, L.; Ionescu, M.; Palibroda, N.; Barzu, O.; Gilles, A.
Regulatory mechanisms differ in UMP kinases from Gram-negative and Gram-positive bacteria
J. Biol. Chem.
282
7242-7253
2007
Streptococcus pneumoniae, Enterococcus faecalis, Haemophilus influenzae, Staphylococcus aureus, Salmonella enterica subsp. enterica serovar Typhimurium, Escherichia coli (A7ZWB7), Bacillus subtilis (O31749), Neisseria meningitidis (P65932)
Tu, J.L.; Chin, K.H.; Wang, A.H.; Chou, S.H.
The crystallization of apo-form UMP kinase from Xanthomonas campestris is significantly improved in a strong magnetic field
Acta Crystallogr. Sect. F
F63
438-442
2007
Xanthomonas campestris pv. campestris, Xanthomonas campestris pv. campestris 17
Egeblad-Welin, L.; Welin, M.; Wang, L.; Eriksson, S.
Structural and functional investigations of Ureaplasma parvum UMP kinase--a potential antibacterial drug target
FEBS J.
274
6403-6414
2007
Ureaplasma parvum (Q9PPX6), Ureaplasma parvum
Meier, C.; Carter, L.G.; Sainsbury, S.; Mancini, E.J.; Owens, R.J.; Stuart, D.I.; Esnouf, R.M.
The crystal structure of UMP kinase from Bacillus anthracis (BA1797) reveals an allosteric nucleotide-binding site
J. Mol. Biol.
381
1098-1105
2008
Bacillus anthracis, Bacillus anthracis (Q81S73), Bacillus anthracis BA1797, Bacillus anthracis BA1797 (Q81S73)
Chilom, C.; Gazdaru, D.; Bucurenci, N.; Straut, M.; Geanta, C.; Popescu, A.
Fluorescent study of the interaction between Staphylococcus aureus UMP kinase and UTP
J. Optoelectron. Adv. Mater.
9
2585-2588
2007
Staphylococcus aureus
-
Meyer, P.; Evrin, C.; Briozzo, P.; Joly, N.; Barzu, O.; Gilles, A.M.
Structural and functional characterization of Escherichia coli UMP kinase in complex with its allosteric regulator GTP
J. Biol. Chem.
283
36011-36018
2008
Escherichia coli (P0A7E9), Escherichia coli
Marco-Marin, C.; Rubio, V.
The site for the allosteric activator GTP of Escherichia coli UMP kinase
FEBS Lett.
583
185-189
2009
Escherichia coli (P0A7E9), Escherichia coli
Chu, C.H.; Liu, M.H.; Chen, P.C.; Lin, M.H.; Li, Y.C.; Hsiao, C.D.; Sun, Y.J.
Structures of Helicobacter pylori uridylate kinase: insight into release of the product UDP
Acta Crystallogr. Sect. D
68
773-783
2012
Helicobacter pylori (P56106), Helicobacter pylori
Lee, M.J.; Chien-Liang, L.; Tsai, J.Y.; Sue, W.T.; Hsia, W.S.; Huang, H.
Identification and biochemical characterization of a unique Mn2+-dependent UMP kinase from Helicobacter pylori
Arch. Microbiol.
192
739-746
2010
Helicobacter pylori (P56106), Helicobacter pylori
Labesse, G.; Benkali, K.; Salard-Arnaud, I.; Gilles, A.M.; Munier-Lehmann, H.
Structural and functional characterization of the Mycobacterium tuberculosis uridine monophosphate kinase: insights into the allosteric regulation
Nucleic Acids Res.
39
3458-3472
2011
Mycobacterium tuberculosis (P9WHK5), Mycobacterium tuberculosis, Mycobacterium tuberculosis H37Rv (P9WHK5)
Hari Prasad, O.; Nanda Kumar, Y.; Reddy, O.V.; Chaudhary, A.; Sarma, P.V.
Cloning, expression, purification and characterization of UMP kinase from Staphylococcus aureus
Protein J.
31
345-352
2012
Staphylococcus aureus (B8XPY6), Staphylococcus aureus, Staphylococcus aureus ATCC 12600 (B8XPY6)
Doig, P.; Gorseth, E.; Nash, T.; Patten, A.; Gao, N.; Blackett, C.
Screening-based discovery of the first novel ATP competitive inhibitors of the Staphylococcus aureus essential enzyme UMP kinase
Biochem. Biophys. Res. Commun.
437
162-167
2013
Staphylococcus aureus, Staphylococcus aureus ATCC 601055
Arvind, A.; Jain, V.; Saravanan, P.; Mohan, C.G.
Uridine monophosphate kinase as potential target for tuberculosis: from target to lead identification
Interdiscip. Sci. Comput. Life Sci.
5
296-311
2013
Mycobacterium tuberculosis (P9WHK5), Mycobacterium tuberculosis, Mycobacterium tuberculosis H37Rv (P9WHK5)
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