Reference on EC 2.7.2.8 - acetylglutamate kinase
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Baich, A.; Vogel, H.J.
N-acetyl-gamma-glutamokinase and N-acetylglutamic gamma-semialdehyde dehydrogenase: Repressible enzymes of arginine synthesis in Escherichia coli
Biochem. Biophys. Res. Commun.
7
491-496
1962
Escherichia coli, Escherichia coli Wc2
Abadjieva, A.; Pauwels, K.; Hilven, P.; Crabeel, M.
A new yeast metabolon involving at least the two first enzymes of arginine biosynthesis. Acetylglutamate synthase activity requires complex formation with acetylglutamate kinase
J. Biol. Chem.
276
42869-42880
2001
Saccharomyces cerevisiae
Pauwels, K.; Abadjieva, A.; Hilven, P.; Stankiewicz, A.; Crabeel, M.
The N-acetylglutamate synthase/N-acetylglutamate kinase metabolon of Saccharomyces cerevisiae allows co-ordinated feedback regulation of the first two steps in arginine biosynthesis
Eur. J. Biochem.
270
1014-1024
2003
Saccharomyces cerevisiae
Vogel, H.J.; McLellan, W.L.
N-Acetyl-gamma-glutamokinase (Escherichia coli)
Methods Enzymol.
17A
251-255
1970
Escherichia coli, Escherichia coli W2D / ATCC 25542
-
Farago, A.; Denes, G.
Mechanism of arginine biosynthesis in Chlamydomonas reinhardti. II. Purification and properties of N-acetylglutamate 5-phosphotransferase, the allosteric enzyme of the pathway
Biochim. Biophys. Acta
136
6-18
1967
Chlamydomonas reinhardtii
Denes, G.
N-Acetylglutamate-5-phosphotransferase
The Enzymes,3rd Ed. (Boyer,P. D. ,ed. )
9
511-520
1973
Chlamydomonas reinhardtii, Escherichia coli
-
Haas, D.; Leisinger, T.
N-acetylglutamate 5-phosphotransferase of Pseudomonas aeruginosa. Purification and ligand-directed association-dissociation
Eur. J. Biochem.
52
365-375
1975
Pseudomonas aeruginosa
Haas, D.; Leisinger, T.
N-acetylglutamate 5-phosphotransferase of Pseudomonas aeruginosa. Catalytic and regulatory properties
Eur. J. Biochem.
52
377-383
1975
Pseudomonas aeruginosa
Wolf, E.C.; Weiss, R.L.
Acetylglutamate kinase. A mitochondrial feedback-sensitive enzyme of arginine biosynthesis in Neurospora crassa
J. Biol. Chem.
255
9189-9195
1980
Neurospora crassa
McKay, G.; Shargool, P.D.
Purification and characterization of N-acetylglutamate 5-phosphotransferase from pea (Pisum sativum) cotyledons
Biochem. J.
195
71-81
1981
Pisum sativum
Gil-Ortiz, F.; Ramon-Maiques, S.; Fita, I.; Rubio, V.
The course of phosphorus in the reaction of N-acetyl-L-glutamate kinase, determined from the structures of crystalline complexes, including a complex with an AlF(4)(-) transition state mimic
J. Mol. Biol.
331
231-244
2003
Escherichia coli (P0A6C8)
Fernandez-Murga, M.L.; Ramon-Maiques, S.; Gil-Ortiz, F.; Fita, I.; Rubio, V.
Towards structural understanding of feedback control of arginine biosynthesis: cloning and expression of the gene for the arginine-inhibited N-acetyl-L-glutamate kinase from Pseudomonas aeruginosa, purification and crystallization of the recombinant enzyme and preliminary X-ray studies
Acta Crystallogr. Sect. D
58
1045-1047
2002
Pseudomonas aeruginosa
Ramon-Maiques, S.; Marina, A.; Gil-Ortiz, F.; Fita, I.; Rubio, V.
Structure of acetylglutamate kinase, a key enzyme for arginine biosynthesis and a prototype for the amino acid kinase enzyme family, during catalysis
Structure
10
329-342
2002
Escherichia coli
Fernandez-Murga, M.L.; Gil-Ortiz, F.; Llacer, J.L.; Rubio, V.
Arginine biosynthesis in Thermotoga maritima: characterization of the arginine-sensitive N-acetyl-L-glutamate kinase
J. Bacteriol.
186
6142-6149
2004
Pseudomonas aeruginosa, Thermotoga maritima
Maheswaran, M.; Urbanke, C.; Forchhammer, K.
Complex formation and catalytic activation by the PII signaling protein of N-acetyl-L-glutamate kinase from Synechococcus elongatus strain PCC 7942
J. Biol. Chem.
279
55202-55210
2004
Synechococcus elongatus
Marco-Marin, C.; Ramon-Maiques, S.; Tavarez, S.; Rubio, V.
Site-directed mutagenesis of Escherichia coli acetylglutamate kinase and aspartokinase III probes the catalytic and substrate-binding mechanisms of these amino acid kinase family enzymes and allows three-dimensional modelling of aspartokinase
J. Mol. Biol.
334
459-476
2003
Escherichia coli (P0A6C8), Escherichia coli
Sugiyama, K.; Hayakawa, T.; Kudo, T.; Ito, T.; Yamaya, T.
Interaction of N-acetylglutamate kinase with a PII-like protein in rice
Plant Cell Physiol.
45
1768-1778
2004
Oryza sativa
Shi, D.; Caldovic, L.; Jin, Z.; Yu, X.; Qu, Q.; Roth, L.; Morizono, H.; Hathout, Y.; Allewell, N.M.; Tuchman, M.
Expression, crystallization and preliminary crystallographic studies of a novel bifunctional N-acetylglutamate synthase/kinase from Xanthomonas campestris homologous to vertebrate N-acetylglutamate synthase
Acta Crystallogr. Sect. F
F62
1218-1222
2006
Xanthomonas campestris (Q8P8J6)
Qu, Q.; Morizono, H.; Shi, D.; Tuchman, M.; Caldovic, L.
A novel bifunctional N-acetylglutamate synthase-kinase from Xanthomonas campestris that is closely related to mammalian N-acetylglutamate synthase
BMC Biochem.
8
4
2007
Xanthomonas campestris (Q8P8J6), Xanthomonas campestris
Ferrario-Mery, S.; Besin, E.; Pichon, O.; Meyer, C.; Hodges, M.
The regulatory PII protein controls arginine biosynthesis in Arabidopsis
FEBS Lett.
580
2015-2020
2006
Arabidopsis thaliana (Q9SCL7)
Chen, Y.M.; Ferrar, T.S.; Lohmeir-Vogel, E.; Morrice, N.; Mizuno, Y.; Berenger, B.; Ng, K.K.; Muench, D.G.; Moorhead, G.B.
The PII signal transduction protein of Arabidopsis thaliana forms an arginine-regulated complex with plastid N-acetyl glutamate kinase
J. Biol. Chem.
281
5726-5733
2006
Arabidopsis thaliana (Q9SCL7), Arabidopsis thaliana
Mizuno, Y.; Moorhead, G.B.; Ng, K.K.
Structural basis for the regulation of N-acetylglutamate kinase by PII in Arabidopsis thaliana
J. Biol. Chem.
282
35733-35740
2007
Arabidopsis thaliana, Arabidopsis thaliana (Q9SCL7)
Ramon-Maiques, S.; Fernandez-Murga, M.L.; Gil-Ortiz, F.; Vagin, A.; Fita, I.; Rubio, V.
Structural bases of feed-back control of arginine biosynthesis, revealed by the structures of two hexameric N-acetylglutamate kinases, from Thermotoga maritima and Pseudomonas aeruginosa
J. Mol. Biol.
356
695-713
2006
Pseudomonas aeruginosa (Q9HTN2), Pseudomonas aeruginosa, Thermotoga maritima (Q9X2A4), Thermotoga maritima
Llacer, J.L.; Contreras, A.; Forchhammer, K.; Marco-Marin, C.; Gil-Ortiz, F.; Maldonado, R.; Fita, I.; Rubio, V.
The crystal structure of the complex of PII and acetylglutamate kinase reveals how PII controls the storage of nitrogen as arginine
Proc. Natl. Acad. Sci. USA
104
17644-17649
2007
Synechococcus elongatus (Q6V1L5), Synechococcus elongatus
Wu, C.W.; Li, L.F.; Liu, X.; Gao, X.Z.; Lei, J.; Su, X.D.; Zhao, X.; Liang, Y.H.
Protein preparation, crystallization and preliminary X-ray crystallographic analysis of N-acetylglutamate kinase from Streptococcus mutans
Protein Pept. Lett.
15
541-543
2008
Streptococcus mutans
Fernandez-Murga, M.L.; Rubio, V.
Basis of arginine sensitivity of microbial N-acetyl-L-glutamate kinases: mutagenesis and protein engineering study with the Pseudomonas aeruginosa and Escherichia coli enzymes
J. Bacteriol.
190
3018-3025
2008
Pseudomonas aeruginosa
Feria Bourrellier, A.; Ferrario-Mry, S.; Vidal, J.; Hodges, M.
Metabolite regulation of the interaction between Arabidopsis thaliana PII and N-acetyl-l-glutamate kinase
Biochem. Biophys. Res. Commun.
387
700-704
2009
Arabidopsis thaliana
Min, L.; Jin, Z.; Caldovic, L.; Morizono, H.; Allewell, N.M.; Tuchman, M.; Shi, D.
Mechanism of allosteric inhibition of N-acetyl-L-glutamate synthase by L-arginine
J. Biol. Chem.
284
4873-4880
2009
Arabidopsis thaliana, Pseudomonas aeruginosa (Q9HTN2)
Beez, S.; Fokina, O.; Herrmann, C.; Forchhammer, K.
N-acetyl-L-glutamate kinase (NAGK) from oxygenic phototrophs: P(II) signal transduction across domains of life reveals novel insights in NAGK control
J. Mol. Biol.
389
748-758
2009
Synechococcus elongatus, Arabidopsis thaliana (Q9SCL7), Arabidopsis thaliana
Shi, D.; Li, Y.; Cabrera-Luque, J.; Jin, Z.; Yu, X.; Zhao, G.; Haskins, N.; Allewell, N.M.; Tuchman, M.
A novel N-acetylglutamate synthase architecture revealed by the crystal structure of the bifunctional enzyme from Maricaulis maris
PLoS ONE
6
e28825
2011
Maricaulis maris
Xu, M.; Rao, Z.; Dou, W.; Yang, J.; Jin, J.; Xu, Z.
Site-directed mutagenesis and feedback-resistant N-acetyl-L-glutamate kinase (NAGK) increase Corynebacterium crenatum L-arginine production
Amino Acids
43
255-266
2012
Corynebacterium crenatum
Xu, M.; Rao, Z.; Dou, W.; Jin, J.; Xu, Z.
Site-directed mutagenesis studies on the L-arginine-binding sites of feedback inhibition in N-acetyl-L-glutamate kinase (NAGK) from Corynebacterium glutamicum
Curr. Microbiol.
64
164-172
2012
Corynebacterium glutamicum
Fokina, O.; Chellamuthu, V.R.; Zeth, K.; Forchhammer, K.
A novel signal transduction protein P(II) variant from Synechococcus elongatus PCC 7942 indicates a two-step process for NAGK-P(II) complex formation
J. Mol. Biol.
399
410-421
2010
Synechococcus elongatus
Gil-Ortiz, F.; Ramon-Maiques, S.; Fernandez-Murga, M.L.; Fita, I.; Rubio, V.
Two crystal structures of Escherichia coli N-acetyl-L-glutamate kinase demonstrate the cycling between open and closed conformations
J. Mol. Biol.
399
476-490
2010
Escherichia coli (A0A140NEG9), Escherichia coli
Marcos, E.; Crehuet, R.; Bahar, I.
Changes in dynamics upon oligomerization regulate substrate binding and allostery in amino acid kinase family members
PLoS Comput. Biol.
7(9)
e1002201
2011
Escherichia coli
de Cima, S.; Gil-Ortiz, F.; Crabeel, M.; Fita, I.; Rubio, V.
Insight on an arginine synthesis metabolon from the tetrameric structure of yeast acetylglutamate kinase
PLoS ONE
7
e34734
2012
Saccharomyces cerevisiae (Q01217), Saccharomyces cerevisiae
Van de Casteele, M.; Demarez, M.; Legrain, C.; Glansdorff, N.; Pierard, A.
Pathways of arginine biosynthesis in extreme thermophilic archaeo- and eubacteria
J. Gen. Microbiol.
136
1177-1183
1990
Saccharolobus solfataricus, Saccharolobus solfataricus P1
-
Zhao, G.; Haskins, N.; Jin, Z.; M Allewell, N.; Tuchman, M.; Shi, D.
Structure of N-acetyl-L-glutamate synthase/kinase from Maricaulis maris with the allosteric inhibitor L-arginine bound
Biochem. Biophys. Res. Commun.
437
585-590
2013
Maricaulis maris (Q0ASS9), Maricaulis maris, Maricaulis maris MCS10 (Q0ASS9), Xanthomonas campestris (A0A0H2X8L7), Xanthomonas campestris 8004 (A0A0H2X8L7)
Zhao, Q.; Luo, Y.; Dou, W.; Zhang, X.; Zhang, X.; Zhang, W.; Xu, M.; Geng, Y.; Rao, Z.; Xu, Z.
Controlling the transcription levels of argGH redistributed L-arginine metabolic flux in N-acetylglutamate kinase and ArgR-deregulated Corynebacterium crenatum
J. Ind. Microbiol. Biotechnol.
43
55-66
2016
Corynebacterium crenatum (Q6R6P5), Corynebacterium crenatum, Corynebacterium crenatum SYPA5-5 (Q6R6P5), Corynebacterium crenatum SYPA5-5
Yang, X.
Conformational dynamics play important roles upon the function of N-acetylglutamate kinase
Appl. Microbiol. Biotechnol.
101
3485-3492
2017
Escherichia coli (P0A6C8), Corynebacterium glutamicum (Q59281), Pseudomonas aeruginosa (Q9HTN2), Thermotoga maritima (Q9X2A4), Corynebacterium glutamicum ATCC 13032 (Q59281)
Liu, W.; Xiang, Y.; Zhang, X.; Han, G.; Sun, X.; Sheng, Y.; Yan, J.; Scheller, H.V.; Zhang, A.
Over-expression of a maize N-acetylglutamate kinase gene (ZmNAGK) improves drought tolerance in tobacco
Front. Plant Sci.
9
1902
2018
Zea mays (A0A1D6E3W6), Zea mays
Zhao, Q.; Luo, Y.; Dou, W.; Zhang, X.; Zhang, X.; Zhang, W.; Xu, M.; Geng, Y.; Rao, Z.; Xu, Z.
Controlling the transcription levels of argGH redistributed L-arginine metabolic flux in N-acetylglutamate kinase and ArgR-deregulated Corynebacterium crenatum
J. Ind. Microbiol. Biotechnol.
43
55-66
2016
Corynebacterium crenatum, Corynebacterium crenatum SYPA5-5
Huang, J.; Chen, D.; Yan, H.; Xie, F.; Yu, Y.; Zhang, L.; Sun, M.; Peng, X.
Acetylglutamate kinase is required for both gametophyte function and embryo development in Arabidopsis thaliana
J. Integr. Plant Biol.
59
642-656
2017
Arabidopsis thaliana (Q9SCL7), Arabidopsis thaliana
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