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Information on EC 2.7.11.33 - [pyruvate, water dikinase] kinase

for references in articles please use BRENDA:EC2.7.11.33
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EC Tree
IUBMB Comments
The enzyme from the bacterium Escherichia coli is bifunctional and catalyses both the phosphorylation and dephosphorylation of EC 2.7.9.2, pyruvate, water dikinase. cf. EC 2.7.4.28, ([pyruvate, water dikinase] phosphate) phosphotransferase . The enzyme is specific for a reaction intermediate form of EC 2.7.9.2, where it phosphorylates an active site histidine . It has no activity toward EC 2.7.9.1 pyruvate, phosphate dikinase (cf. EC 2.7.11.32, [pyruvate, phosphate dikinase] kinase).
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The enzyme appears in viruses and cellular organisms
Reaction Schemes
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[pyruvate, water dikinase]
=
+
[pyruvate, water dikinase] phosphate
Synonyms
bifunctional ADP-dependent kinase - Pi-dependent pyrophosphorylase, DUF299, PEP synthetase regulatory protein, PEPS kinase, PSRP, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
ADP + [pyruvate, water dikinase] = AMP + [pyruvate, water dikinase] phosphate
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