Reference on EC 2.7.1.39 - homoserine kinase
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Aarnes, H.
Homoserine kinase from barley seedlings
Plant Sci. Lett.
7
187-194
1976
Hordeum vulgare
-
Thoen, A.; Rognes, S.E.; Aarnes, H.
Biosynthesis of threonine from homoserine in pea seedlings: I. Homoserine kinase
Plant Sci. Lett.
13
103-112
1978
Pisum sativum
-
Baum, H.J.; Madison, J.T.; Thompson, J.F.
Feedback inhibition of homoserine kinase from radish leaves
Phytochemistry
22
2409-2412
1983
Raphanus sativus
-
Shames, S.L.; Wedler, F.C.
Homoserine kinase of Escherichia coli: kinetic mechanism and inhibition by L-aspartate semialdehyde
Arch. Biochem. Biophys.
235
359-370
1984
Escherichia coli
Finkelnburg, B.; Klemme, J.H.
Homoserine kinase from phototrophic bacterium Rhodospirillum rubrum is not sensitive to feedback inhibition by L-Thr
FEMS Microbiol. Lett.
48(1-2)
93-96
1987
Rhodospirillum rubrum, Rhodospirillum rubrum S1
-
Theze, J.; Kleidman, L.; Saint Girons, I.
Homoserine kinase from Escherichia coli K-12: properties, inhibition by L-threonine, and regulation of biosynthesis
J. Bacteriol.
118
577-581
1974
Escherichia coli
Miyajima, R.; Shiio, I.
Regulation of aspartate family amino acid biosynthesis in Brevibacterium flavum. V. Properties of homoserine kinase
J. Biochem.
71
219-226
1972
[Brevibacterium] flavum
Riesmeier, J.; Klonus, A.K.; Pohlenz, H.D.
Purification to homogeneity and characterization of homoserine racemase from wheat germ
Phytochemistry
32
581-584
1993
Triticum aestivum
-
Ramos, C.; Delgado, M.A.; Calderon, I.L.
Inhibition by different amino acids of the aspartate kinase and the homoserine kinase of the yeast Saccharomyces cerevisiae
FEBS Lett.
278
123-126
1991
Saccharomyces cerevisiae
Mannhaupt, G.; Pohlenz, H.D.; Seefluth, A.K.; Pilz, U.; Feldmann, H.
Yeast homoserine kinase. Characteristics of the corresponding gene, THR1, and the purified enzyme, and evolutionary relationships with other enzymes of threonine metabolism
Eur. J. Biochem.
191
115-122
1990
Saccharomyces cerevisiae
Burr, B.; Walker, J.; Truffa-Bachi, P.; Cohen, G.N.
Homoserine kinase from Escherichia coli K12
Eur. J. Biochem.
62
519-526
1976
Escherichia coli
Huo, X.; Viola, R.E.
Substrate specificity and identification of functional groups of homoserine kinase from Escherichia coli
Biochemistry
35
16180-16185
1996
Escherichia coli
Lee, M.; Leustek, T.
Identification of the gene encoding homoserine kinase from Arabidopsis thaliana and characterization of the recombinant enzyme derived from the gene
Arch. Biochem. Biophys.
372
135-142
1999
Arabidopsis thaliana (Q8L7R2), Arabidopsis thaliana
Huo, X.; Viola, R.E.
Functional group characterization of homoserine kinase from Escherichia coli
Arch. Biochem. Biophys.
330
373-379
1996
Escherichia coli
Zhou, T.; Daugherty, M.; Grishin, N.V.; Osterman, A.L.; Zhang, H.
Structure and mechanism of homoserine kinase: prototype for the GHMP kinase superfamily
Structure Fold. Des.
8
1247-1257
2000
Methanocaldococcus jannaschii
Krishna, S.S.; Zhou, T.; Daugherty, M.; Osterman, A.; Zhang, H.
Structural basis for the catalysis and substrate specificity of homoserine kinase
Biochemistry
40
10810-10818
2001
Methanocaldococcus jannaschii (Q58504), Methanocaldococcus jannaschii
Patte, J.C.; Clepet, C.; Bally, M.; Borne, F.; Mejean, V.; Foglino, M.
ThrH, a homoserine kinase isozyme with in vivo phosphoserine phosphatase activity in Pseudomonas aeruginosa
Microbiology
145
845-853
1999
Pseudomonas aeruginosa
Bareich, D.; Koteva, K.; Nazi, I.; Wright, G.D.
Small molecule functional discrimination of the kinases required for the microbial synthesis of threonine and isoleucine
Bioorg. Med. Chem.
12
807-815
2004
Schizosaccharomyces pombe
Fernandez, M.; Cuadrado, Y.; Aparicio, J.F.; Martin, J.F.
Role of homoserine and threonine pathway intermediates as precursors for the biosynthesis of aminoethoxyvinylglycine in Streptomyces sp. NRRL 5331
Microbiology
150
1467-1474
2004
Streptomyces sp., Streptomyces sp. NRRL 5331
Lee, M.; Martin, M.N.; Hudson, A.O.; Lee, J.; Muhitch, M.J.; Leustek, T.
Methionine and threonine synthesis are limited by homoserine availability and not the activity of homoserine kinase in Arabidopsis thaliana
Plant J.
41
685-696
2005
Arabidopsis thaliana (Q8L7R2), Arabidopsis thaliana
Paik, S.; Senty, L.; Das, S.; Noe, J.C.; Munro, C.L.; Kitten, T.
Identification of virulence determinants for endocarditis in Streptococcus sanguinis by signature-tagged mutagenesis
Infect. Immun.
73
6064-6074
2005
Streptococcus sanguinis, Streptococcus sanguinis SK36
Rinder, J.; Casazza, A.P.; Hoefgen, R.; Hesse, H.
Regulation of aspartate-derived amino acid homeostasis in potato plants (Solanum tuberosum L.) by expression of E. coli homoserine kinase
Amino Acids
34
213-222
2008
Escherichia coli
Kingsbury, J.M.; McCusker, J.H.
Threonine biosynthetic genes are essential in Cryptococcus neoformans
Microbiology
154
2767-2775
2008
Cryptococcus neoformans
Stockbridge, R.B.; Wolfenden, R.
The intrinsic reactivity of ATP and the catalytic proficiencies of kinases acting on glucose, N-acetylgalactosamine, and homoserine: a thermodynamic analysis
J. Biol. Chem.
284
22747-22757
2009
Methanocaldococcus jannaschii
van Damme, M.; Zeilmaker, T.; Elberse, J.; Andel, A.; de Sain-van der Velden, M.; van den Ackerveken, G.
Downy mildew resistance in Arabidopsis by mutation of homoserine kinase
Plant Cell
21
2179-2189
2009
Arabidopsis thaliana (Q8L7R2), Arabidopsis thaliana
De Pascale, G.; Griffiths, E.; Shakya, T.; Nazi, I.; Wright, G.
Identification and characterization of new inhibitors of fungal homoserine kinase
ChemBioChem
12
1179-1182
2011
Schizosaccharomyces pombe
Kingsbury, J.M.; McCusker, J.H.
Homoserine toxicity in Saccharomyces cerevisiae and Candida albicans homoserine kinase (thr1Delta) mutants
Eukaryot. Cell
9
717-728
2010
Saccharomyces cerevisiae, Candida albicans, Saccharomyces cerevisiae YJM145
Kingsbury, J.M.; McCusker, J.H.
Fungal homoserine kinase (thr1Delta) mutants are attenuated in virulence and die rapidly upon threonine starvation and serum incubation
Eukaryot. Cell
9
729-737
2010
Saccharomyces cerevisiae, Candida albicans
Brewer, H.C.; Hawkins, N.D.; Hammond-Kosack, K.E.
Mutations in the Arabidopsis homoserine kinase gene DMR1 confer enhanced resistance to Fusarium culmorum and F. graminearum
BMC Plant Biol.
14
317
2014
Arabidopsis thaliana (Q8L7R2)
Petit, C.; Kim, Y.; Lee, S.K.; Brown, J.; Larsen, E.; Ronning, D.R.; Suh, J.W.; Kang, C.M.
Reduction of feedback inhibition in homoserine kinase (ThrB) of Corynebacterium glutamicum enhances L-threonine biosynthesis
ACS omega
3
1178-1186
2018
Corynebacterium glutamicum (P07128), Corynebacterium glutamicum, Corynebacterium glutamicum LMG 3730 (P07128), Corynebacterium glutamicum BCRC 11384 (P07128), Corynebacterium glutamicum ATCC 13032 (P07128), Corynebacterium glutamicum JCM 1318 (P07128), Corynebacterium glutamicum NCIMB 10025 (P07128), Corynebacterium glutamicum DSM 20300 (P07128)
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