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Reference on EC 2.6.1.83 - LL-diaminopimelate aminotransferase

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Hudson, A.O.; Singh, B.K.; Leustek, T.; Gilvarg, C.
An LL-diaminopimelate aminotransferase defines a novel variant of the lysine biosynthesis pathway in plants
Plant Physiol.
140
292-301
2006
Arabidopsis thaliana, Arabidopsis thaliana (Q93ZN9)
Manually annotated by BRENDA team
Watanabe, N.; Cherney, M.M.; van Belkum, M.J.; Marcus, S.L.; Flegel, M.D.; Clay, M.D.; Deyholos, M.K.; Vederas, J.C.; James, M.N.
Crystal structure of LL-diaminopimelate aminotransferase from Arabidopsis thaliana: a recently discovered enzyme in the biosynthesis of L-lysine by plants and chlamydia
J. Mol. Biol.
371
685-702
2007
Arabidopsis thaliana (Q93ZN9), Arabidopsis thaliana
Manually annotated by BRENDA team
Hudson, A.O.; Gilvarg, C.; Leustek, T.
Biochemical and phylogenetic characterization of a novel diaminopimelate biosynthesis pathway in prokaryotes identifies a diverged form of LL-diaminopimelate aminotransferase
J. Bacteriol.
190
3256-3263
2008
Syntrophobacter fumaroxidans (A0LEA5), Methanothermobacter thermautotrophicus (O26158), Aquifex aeolicus (O66630), Chlamydia trachomatis (O84395), Desulfitobacterium hafniense (Q18T09), Methanosphaera stadtmanae (Q2NFU1), Moorella thermoacetica (Q2RK33), Trichormus variabilis (Q3MAL4), Trichormus variabilis (Q3MDN5), Synechocystis sp. (Q55828), Bacteroides fragilis (Q5LC03), Candidatus Protochlamydia amoebophila (Q6MDE0), Leptospira interrogans (Q72NJ3), Geobacter sulfurreducens (Q74GT3), Gloeobacter violaceus (Q7NDX4), Methanosarcina acetivorans (Q8TQ40)
Manually annotated by BRENDA team
Fan, C.; Clay, M.D.; Deyholos, M.K.; Vederas, J.C.
Exploration of inhibitors for diaminopimelate aminotransferase
Bioorg. Med. Chem.
18
2141-2151
2010
Arabidopsis thaliana
Manually annotated by BRENDA team
Watanabe, N.; Clay, M.D.; van Belkum, M.J.; Cherney, M.M.; Vederas, J.C.; James, M.N.
Mechanism of substrate recognition and PLP-induced conformational changes in LL-diaminopimelate aminotransferase from Arabidopsis thaliana
J. Mol. Biol.
384
1314-1329
2008
Arabidopsis thaliana (Q93ZN9), Arabidopsis thaliana
Manually annotated by BRENDA team
Hudson, A.O.; Giron, I.; Dobson, R.C.
Crystallization and preliminary X-ray diffraction analysis of L,L-diaminopimelate aminotransferase (DapL) from Chlamydomonas reinhardtii
Acta Crystallogr. Sect. F
67
140-143
2011
Chlamydomonas reinhardtii, Chlamydomonas reinhardtii CC-1690
Manually annotated by BRENDA team
Sobolev, V.; Edelman, M.; Dym, O.; Unger, T.; Albeck, S.; Kirma, M.; Galili, G.
Structure of ALD1, a plant-specific homologue of the universal diaminopimelate aminotransferase enzyme of lysine biosynthesis
Acta Crystallogr. Sect. F
69
84-89
2013
Arabidopsis thaliana (Q9ZQI7), Arabidopsis thaliana
Manually annotated by BRENDA team
Watanabe, N.; James, M.N.
Structural insights for the substrate recognition mechanism of LL-diaminopimelate aminotransferase
Biochim. Biophys. Acta
1814
1528-1533
2011
Arabidopsis thaliana, Chlamydia trachomatis
Manually annotated by BRENDA team
Nachar, V.R.; Savka, F.C.; McGroty, S.E.; Donovan, K.A.; North, R.A.; Dobson, R.C.; Buckley, L.J.; Hudson, A.O.
Genomic and biochemical analysis of the diaminopimelate and lysine biosynthesis pathway in Verrucomicrobium spinosum: Identification and partial characterization of L,L-diaminopimelate aminotransferase and UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-meso-diaminopimelate ligase
Front. Microbiol.
3
183
2012
Verrucomicrobium spinosum, Verrucomicrobium spinosum DSM 4136T
Manually annotated by BRENDA team
Liu, Y.; White, R.H.; Whitman, W.B.
Methanococci use the diaminopimelate aminotransferase (DapL) pathway for lysine biosynthesis
J. Bacteriol.
192
3304-3310
2010
Methanococcus maripaludis
Manually annotated by BRENDA team
Watanabe, N.; Clay, M.D.; van Belkum, M.J.; Fan, C.; Vederas, J.C.; James, M.N.
The structure of LL-diaminopimelate aminotransferase from Chlamydia trachomatis: implications for its broad substrate specificity
J. Mol. Biol.
411
649-660
2011
Chlamydia trachomatis (O84395), Chlamydia trachomatis
Manually annotated by BRENDA team
Fan, C.; Vederas, J.C.
Synthesis and structure-activity relationships of o-sulfonamido-arylhydrazides as inhibitors of LL-diaminopimelate aminotransferase (LL-DAP-AT)
Org. Biomol. Chem.
10
5815-5819
2012
Arabidopsis thaliana
Manually annotated by BRENDA team
Dobson, R.C.; Giron, I.; Hudson, A.O.
L,L-diaminopimelate aminotransferase from Chlamydomonas reinhardtii: a target for algaecide development
PLoS ONE
6
e20439
2011
Chlamydomonas reinhardtii (A8IW39), Chlamydomonas reinhardtii, Chlamydomonas reinhardtii CC-1690 (A8IW39)
Manually annotated by BRENDA team
McKinnie, S.M.; Rodriguez-Lopez, E.M.; Vederas, J.C.; Crowther, J.M.; Suzuki, H.; Dobson, R.C.; Leustek, T.; Triassi, A.J.; Wheatley, M.S.; Hudson, A.O.
Differential response of orthologous L,L-diaminopimelate aminotransferases (DapL) to enzyme inhibitory antibiotic lead compounds
Bioorg. Med. Chem.
22
523-530
2014
Chlamydomonas reinhardtii (A8IW39), Chlamydomonas reinhardtii, Leptospira interrogans (Q72NJ3), Leptospira interrogans, Verrucomicrobium spinosum (WP_009961032), Verrucomicrobium spinosum
Manually annotated by BRENDA team
Weatherhead, A.W.; Crowther, J.M.; Horne, C.R.; Meng, Y.; Coombes, D.; Currie, M.J.; Watkin, S.A.J.; Adams, L.E.; Parthasarathy, A.; Dobson, R.C.J.; Hudson, A.O.
Structure-function studies of the antibiotic target L,L-diaminopimelate aminotransferase from Verrucomicrobium spinosum reveal an unusual oligomeric structure
Biochemistry
59
2274-2288
2020
Verrucomicrobium spinosum (A0A6P3CW87), Verrucomicrobium spinosum
Manually annotated by BRENDA team
Adams, L.E.; Rynkiewicz, P.; Babbitt, G.A.; Mortensen, J.S.; North, R.A.; Dobson, R.C.J.; Hudson, A.O.
Comparative molecular dynamics simulations provide insight into antibiotic interactions a case study using the enzyme L,L-diaminopimelate aminotransferase (DapL)
Front. Mol. Biosci.
7
46
2020
Verrucomicrobium spinosum (A0A6P3CW87), Verrucomicrobium spinosum
Manually annotated by BRENDA team
Sadhasivam, A.; Vetrivel, U.
Identification of potential drugs targeting L,L-diaminopimelate aminotransferase of Chlamydia trachomatis an integrative pharmacoinformatics approach
J. Cell. Biochem.
120
2271-2288
2019
Chlamydia trachomatis
Manually annotated by BRENDA team
Cavalcanti, J.H.F.; Kirma, M.; Barros, J.A.S.; Quinhones, C.G.S.; Pereira-Lima, I.A.; Obata, T.; Nunes-Nesi, A.; Galili, G.; Fernie, A.R.; Avin-Wittenberg, T.; Araujo, W.L.
An L,L-diaminopimelate aminotransferase mutation leads to metabolic shifts and growth inhibition in Arabidopsis
J. Exp. Bot.
69
5489-5506
2018
Arabidopsis thaliana (Q93ZN9), Arabidopsis thaliana Col-0 (Q93ZN9)
Manually annotated by BRENDA team