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Information on EC 2.6.1.76 - diaminobutyrate-2-oxoglutarate transaminase

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EC Tree
     2 Transferases
         2.6 Transferring nitrogenous groups
             2.6.1 Transaminases
                2.6.1.76 diaminobutyrate-2-oxoglutarate transaminase
IUBMB Comments
A pyridoxal-phosphate protein that requires potassium for activity . In the proteobacterium Acinetobacter baumannii, this enzyme is cotranscribed with the neighbouring ddc gene that also encodes EC 4.1.1.86, diaminobutyrate decarboxylase. Differs from EC 2.6.1.46, diaminobutyrate---pyruvate transaminase, which has pyruvate as the amino-group acceptor. This is the first enzyme in the ectoine-biosynthesis pathway, the other enzymes involved being EC 2.3.1.178, diaminobutyrate acetyltransferase and EC 4.2.1.108, ectoine synthase [3,4].
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Word Map
The expected taxonomic range for this enzyme is: Bacteria, Eukaryota
Synonyms
daba at, l-2,4-diaminobutyrate:2-ketoglutarate 4-aminotransferase, daba aminotransferase, 2,4-diaminobutyrate aminotransferase, more
REACTION
REACTION DIAGRAM
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ORGANISM
UNIPROT
LITERATURE
L-2,4-diaminobutanoate + 2-oxoglutarate = L-aspartate 4-semialdehyde + L-glutamate
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