the structure of the protein is a homodimer that adopts the type I fold of pyridoxal 5'-phosphate-dependent aminotransferases. The structure reveals the PLP cofactor covalently bound in the active site to the active-site lysine in the internal aldimine form
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1.8 A resolution. The structure of the Sulfolobus solfataricus enzyme is determined with an amino form of the cofactor pyridoxamine 5'-phosphate bound in the active site and in complex with gabaculine, an aminotransferase inhibitor. These structures show the changes in the enzyme active site during the course of the catalytic reaction