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Information on EC 2.6.1.22 - (S)-3-amino-2-methylpropionate transaminase

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EC Tree
     2 Transferases
         2.6 Transferring nitrogenous groups
             2.6.1 Transaminases
                2.6.1.22 (S)-3-amino-2-methylpropionate transaminase
IUBMB Comments
Also acts on beta-alanine and other omega-amino acids having carbon chains between 2 and 5. The two enantiomers of the 2-methyl-3-oxopropanoate formed by the enzyme interconvert by enolization, so that this enzyme, together with EC 2.6.1.40, (R)-3-amino-2-methylpropionate---pyruvate transaminase, provide a route for interconversion of the enantiomers of 3-amino-2-methylpropanoate.
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The enzyme appears in viruses and cellular organisms
Synonyms
aminotransferase, L-3-aminoisobutyrate, beta-aminobutyric transaminase, L-3-aminoisobutyrate transaminase, L-3-aminoisobutyric aminotransferase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
(S)-3-amino-2-methylpropanoate + 2-oxoglutarate = 2-methyl-3-oxopropanoate + L-glutamate
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