Reference on EC 2.6.1.16 - glutamine-fructose-6-phosphate transaminase (isomerizing)

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Ghosh, S.; Blumenthal, H.J.; Davidson, E.; Roseman, S.
Glucosamine metabolism.V. Enzymatic synthesis of glucosamine 6-phosphate
J. Biol. Chem.
235
1265-1273
1960
Aspergillus flavus, Aspergillus parasiticus, Colletotrichum gloeosporioides, Escherichia coli, Helminthosporium sativum, Hypomyces rosellus, Neurospora crassa, Neurospora tetrasperma, Penicillium chrysogenum, Penicillium sp., Rattus norvegicus
Manually annotated by BRENDA team
Gryder, R.M.; Pogell, B.M.
Further studies on glucosamine 6-phosphate synthesis by rat liver enzymes
J. Biol. Chem.
235
558-562
1960
Rattus norvegicus
Manually annotated by BRENDA team
Trujillo, J.L.; Gan, J.C.
Purification and some kinetic properties of bovine thyroid gland L-glutamine D-fructose-6-phosphate amidotransferase
Int. J. Biochem.
5
515-523
1974
Bos taurus
-
Manually annotated by BRENDA team
Malathy, K.; Kurup, P.A.
Inhibition of hexosephosphate aminotransferase activity in vitro by tolbutamide
Indian J. Biochem. Biophys.
9
310-312
1972
Rattus norvegicus
Manually annotated by BRENDA team
Ikeda, Y.; Tsuiki, S.
Occurrence and properties of a natural activator of L-glutamine:D-fructose 6-phosphate amidotransferase
Sci. Rep. Res. Inst. Tohoku Univ. Med.
19
53-63
1972
Mus musculus, Rattus norvegicus
Manually annotated by BRENDA team
Chmara, H.; Andruszkiewicz, R.; Borowski, E.
Inactivation of glucosamine-6-phosphate synthetase from Salmonella typhimurium LT 2 SL 1027 by N beta-fumarylcarboxyamido-L-2,3-diamino-propionic acid
Biochem. Biophys. Res. Commun.
120
865-872
1984
Salmonella enterica subsp. enterica serovar Typhimurium, Salmonella enterica subsp. enterica serovar Typhimurium LT2
Manually annotated by BRENDA team
Chmara, H.; Andruszkiewicz, R.; Borowski, E.
Inactivation of glucosamine-6-phosphate synthethase from Salmonella typhimurium LT2 by fumarolyl diaminopropanoic acid derivatives, a novel group of glutamine analogs
Biochim. Biophys. Acta
870
357-366
1985
Salmonella enterica subsp. enterica serovar Typhimurium, Salmonella enterica subsp. enterica serovar Typhimurium LT2
Manually annotated by BRENDA team
Chmara, H.; Zähner, H.
The inactivation of glucosamine synthetase from bacteria by anticapsin, the C-terminal epoxyamino acid of the antibiotic tetaine
Biochim. Biophys. Acta
787
45-52
1984
Bacillus thuringiensis, Escherichia coli, Paenarthrobacter aurescens, Pseudomonas aeruginosa
Manually annotated by BRENDA team
Kikuchi, H.; Ikeda, Y.; Tsuiki, S.
Inhibition of L-glutamine:D-fructose-6-phosphate aminotransferase by methylglyoxal
Biochim. Biophys. Acta
289
303-310
1972
Rattus norvegicus
Manually annotated by BRENDA team
Norrman, J.; Myers, R.B.; Giddings, T.H.; Cantino, E.C.
Partial purification of L-glutamine:D-fructose 6-phosphate aminotransferase from zoospores of Blastocladiella emersonii
Biochim. Biophys. Acta
302
173-177
1973
Blastocladiella emersonii
Manually annotated by BRENDA team
McKnight, G.L.; Mudri, S.L.; Mathewes, S.L.; Traxinger, R.R.; Marshall, S.; Sheppard, P.O.; O'Hara, P.J.
Molecular cloning, cDNA sequence, and bacterial expression of human glutamine:fructose-6-phosphate amidotransferase
J. Biol. Chem.
267
25208-25212
1992
Homo sapiens
Manually annotated by BRENDA team
Hosoi, K.; Kobayashi, S.; Ueha, T.
Affinity adsorption of L-glutamine D-fructose-6-phosphate aminotransferase to Sepharose coupled with p-chloromercuribenzoate
Biochem. Biophys. Res. Commun.
85
558-563
1978
Mus musculus
Manually annotated by BRENDA team
Milewski, S.; Chmara, H.; Andruszkiewicz, R.; Borowski, E.
N3-haloacetyl derivatives of L-2,3-diaminopropanoic acid: novel inactivators of glucosamine-6-phosphate synthase
Biochim. Biophys. Acta
1115
225-229
1992
Bacillus pumilus, Candida albicans, Escherichia coli
Manually annotated by BRENDA team
Badet, B.; Vermoote, P.; Le Goffic, F.
Glucosamine synthetase from Escherichia coli: kinetic mechanism and inhibition by N3-fumaroyl-L-2,3-diaminopropionic derivatives
Biochemistry
27
2282-2287
1988
Escherichia coli
Manually annotated by BRENDA team
Calcagno, M.; Levy, J.A.; Arrambide, E.; Mizraji, E.
L-glutamine:D-fructose 6-phosphate amidotransferase of chick cartilage. Evidence for a random mechanism
Enzymologia
41
175-182
1971
Gallus gallus
-
Manually annotated by BRENDA team
Zalkin, H.
Glucosamine-6-phosphate synthase
Methods Enzymol.
113
278-281
1985
Rattus norvegicus
Manually annotated by BRENDA team
Ellis, D.B.; Sommar, K.M.
Biosynthesis of respiratory tract musins. II. Control of hexosamine metabolism by L-glutamine D-fructose 6-phosphate aminotransferase
Biochim. Biophys. Acta
267
105-112
1972
Bos taurus
Manually annotated by BRENDA team
Moriguchi, M.; Yamamoto, K.; Kawai, H.; Tochikura, T.
The partial purification of by L-glutamine D-fructose 6-phosphate amidotransferase from Baker's yeast
Agric. Biol. Chem.
40
1655-1656
1976
Saccharomyces cerevisiae
-
Manually annotated by BRENDA team
Badet, B.; Vermoote, P.; Haumont, P.Y.; Lederer, F.; Le Goffic, F.
Glucosamine synthetase from Escherichia coli: purification, properties, and glutamine-utilizing site location
Biochemistry
26
1940-1948
1987
Escherichia coli
Manually annotated by BRENDA team
Vessal, M.; Hassid, W.Z.
Partial purification and properties of L-glutamine D-fructose 6-phosphate amidotransferase from Phaseolus aureus
Plant Physiol.
49
977-981
1972
Vigna radiata var. radiata
Manually annotated by BRENDA team
Kikuchi, H.; Tsuiki, S.
Stabilization of glucosaminephosphate synthase from rat liver by hexose 6-phosphates. Properties and interconversion of two molecular forms
Biochim. Biophys. Acta
422
231-240
1976
Rattus norvegicus
Manually annotated by BRENDA team
Kikuchi, H.; Tsuiki, S.
Glucosaminephosphate synthase of human liver
Biochim. Biophys. Acta
422
241-246
1976
Homo sapiens
Manually annotated by BRENDA team
Badet-Denisot, M.A.; Leriche, C.; Massiere, F.; Badet, B.
Nitrogen transfer in E. coli glucosamine-6P synthase. Investigations using substrate and bisubstrate analogs
Bioorg. Med. Chem. Lett.
5
815-820
1995
Escherichia coli
-
Manually annotated by BRENDA team
Bearne, S.L.
Active site-directed inactivation of Escherichia coli glucosamine-6-phosphate synthase. Determination of the fructose 6-phosphate binding constant using a carbohydrate-based inactivator
J. Biol. Chem.
271
3052-3057
1996
Escherichia coli
Manually annotated by BRENDA team
Hebert, L.F., Jr.; Daniels, M.C.; Zhou, J.; Crook, E.D.; Turner, R.L.; Simmons, S.T.; Neidigh, J.L.; Zhu, J.S.; Baron, A.D.; McClain, D.A.
Overexpression of glutamine:fructose-6-phosphate amidotransferase in transgenic mice leads to insulin resistance
J. Clin. Invest.
98
930-936
1996
Rattus norvegicus
Manually annotated by BRENDA team
Leriche, C.; Badet-Denisot, M.A.; Badet, B.
Affinity labeling of Escherichia coli glucosamine-6-phosphate synthase with a fructose 6-phosphate analog. Evidence for proximity between the N-terminal cysteine and the fructose-6-phosphate-binding site
Eur. J. Biochem.
245
418-422
1997
Escherichia coli
Manually annotated by BRENDA team
Teplyakov A.; Galya O.; Badet-Denisot, M.; Badet B.
The mechanism of sugar phosphate isomerization by glucosamine 6-phosphate synthase
Protein Sci.
8
596-602
1999
Escherichia coli
Manually annotated by BRENDA team
Huynh, Q.K.; Gulve, E.A.; Dian, T.
Purification and characterization of glutamine:fructose 6-phosphate amidotransferase from rat liver
Arch. Biochem. Biophys.
379
307-313
2000
Rattus norvegicus
Manually annotated by BRENDA team
Teplyakov, A.; Obmolova, G.; Badet, B.; Badet-Denisot, M.A.
Channeling of ammonia in glucosamine-6-phosphate synthase
J. Mol. Biol.
313
1093-1102
2001
Escherichia coli, Escherichia coli (P17169)
Manually annotated by BRENDA team
Todorova, R.
Isomerase activity of the C-terminal fructose-6-phosphate binding domain of glucosamine-6-phosphate synthase from Escherichia coli
J. Enzyme Inhib.
16
373-380
2001
Escherichia coli
Manually annotated by BRENDA team
Chmara, H.; Zahner, H.; Borowski, E.; Milewski, S.
Inhibition of glucosamine-6-phosphate synthetase from bacteria by anticapsin
J. Antibiot.
37
652-658
1984
Bacteria
Manually annotated by BRENDA team
Wojciechowski, M.; Milewski, S.; Mazerski, J.; Borowski, E.
Glucosamine-6-phosphate synthase, a novel target for antifungal agents. Molecular modelling studies in drug design
Acta Biochim. Pol.
52
647-653
2005
Homo sapiens
Manually annotated by BRENDA team
Olchowy, J.; Jedrzejczak, R.; Milewski, S.; Rypniewski, W.
Crystallization and preliminary X-ray analysis of the isomerase domain of glucosamine-6-phosphate synthase from Candida albicans
Acta Crystallogr. Sect. F
61
994-996
2005
Candida albicans
Manually annotated by BRENDA team
Milewski, S.; Janiak, A.; Wojciechowski, M.
Structural analogues of reactive intermediates as inhibitors of glucosamine-6-phosphate synthase and phosphoglucose isomerase
Arch. Biochem. Biophys.
450
39-49
2006
Candida albicans
Manually annotated by BRENDA team
Olchowy, J.; Gabriel, I.; Milewski, S.
Functional domains and interdomain communication in Candida albicans glucosamine-6-phosphate synthase
Biochem. J.
404
121-130
2007
Candida albicans
Manually annotated by BRENDA team
Deng, M.D.; Grund, A.D.; Wassink, S.L.; Peng, S.S.; Nielsen, K.L.; Huckins, B.D.; Burlingame, R.P.
Directed evolution and characterization of Escherichia coli glucosamine synthase
Biochimie
88
419-429
2006
Escherichia coli
Manually annotated by BRENDA team
Floquet, N.; Richez, C.; Durand, P.; Maigret, B.; Badet, B.; Badet-Denisot, M.A.
Discovering new inhibitors of bacterial glucosamine-6P synthase (GlmS) by docking simulations
Bioorg. Med. Chem. Lett.
17
1966-1970
2007
Escherichia coli (P17169)
Manually annotated by BRENDA team
Floquet, N.; Mouilleron, S.; Daher, R.; Maigret, B.; Badet, B.; Badet-Denisot, M.A.
Ammonia channeling in bacterial glucosamine-6-phosphate synthase (Glms): molecular dynamics simulations and kinetic studies of protein mutants
FEBS Lett.
581
2981-2987
2007
Escherichia coli, Escherichia coli (P17169)
Manually annotated by BRENDA team
Manzari, B.; Kudlow, J.E.; Fardin, P.; Merello, E.; Ottaviano, C.; Puppo, M.; Eva, A.; Varesio, L.
Induction of macrophage glutamine: fructose-6-phosphate amidotransferase expression by hypoxia and by picolinic acid
Int. J. Immunopathol. Pharmacol.
20
47-58
2007
Mus musculus
Manually annotated by BRENDA team
Huang, X.; Tsuji, N.; Miyoshi, T.; Motobu, M.; Islam, M.K.; Alim, M.A.; Fujisaki, K.
Characterization of glutamine: fructose-6-phosphate aminotransferase from the ixodid tick, Haemaphysalis longicornis, and its critical role in host blood feeding
Int. J. Parasitol.
37
383-392
2007
Haemaphysalis longicornis
Manually annotated by BRENDA team
Dummitt, B.; Micka, W.S.; Chang, Y.H.
Yeast glutamine-fructose-6-phosphate aminotransferase (Gfa1) requires methionine aminopeptidase activity for proper function
J. Biol. Chem.
280
14356-14360
2005
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Mouilleron, S.; Badet-Denisot, M.A.; Golinelli-Pimpaneau, B.
Glutamine binding opens the ammonia channel and activates glucosamine-6P synthase
J. Biol. Chem.
281
4404-4412
2006
Escherichia coli (P17169)
Manually annotated by BRENDA team
Kunika, K.; Tanahashi, T.; Kudo, E.; Mizusawa, N.; Ichiishi, E.; Nakamura, N.; Yoshikawa, T.; Yamaoka, T.; Yasumo, H.; Tsugawa, K.; Moritani, M.; Inoue, H.; Itakura, M.
Effect of +36T>C in intron 1 on the glutamine: fructose-6-phosphate amidotransferase 1 gene and its contribution to type 2 diabetes in different populations
J. Hum. Genet.
51
1100-1109
2006
Homo sapiens
Manually annotated by BRENDA team
Olchowy, J.; Kur, K.; Sachadyn, P.; Milewski, S.
Construction, purification, and functional characterization of His-tagged Candida albicans glucosamine-6-phosphate synthase expressed in Escherichia coli
Protein Expr. Purif.
46
309-315
2006
Candida albicans
Manually annotated by BRENDA team
Mouilleron, S.; Golinelli-Pimpaneau, B.
Domain motions of glucosamine-6P synthase: comparison of the anisotropic displacements in the crystals and the catalytic hinge-bending rotation
Protein Sci.
16
485-493
2007
Escherichia coli
Manually annotated by BRENDA team
Li, Y.; Lopez, P.; Durand, P.; Ouazzani, J.; Badet, B.; Badet-Denisot, M.A.
An enzyme-coupled assay for amidotransferase activity of glucosamine-6-phosphate synthase
Anal. Biochem.
370
142-146
2007
Escherichia coli
Manually annotated by BRENDA team
Foley, S.; Stolarczyk, E.; Mouni, F.; Brassart, C.; Vidal, O.; Aissi, E.; Bouquelet, S.; Krzewinski, F.
Characterisation of glutamine fructose-6-phosphate amidotransferase (EC 2.6.1.16) and N-acetylglucosamine metabolism in Bifidobacterium
Arch. Microbiol.
189
157-167
2008
Bifidobacterium longum, Bifidobacterium longum (Q8G545)
Manually annotated by BRENDA team
Li, Y.; Roux, C.; Lazereg, S.; LeCaer, J.P.; Laprevote, O.; Badet, B.; Badet-Denisot, M.A.
Identification of a novel serine phosphorylation site in human glutamine:fructose-6-phosphate amidotransferase isoform 1
Biochemistry
46
13163-13169
2007
Homo sapiens
Manually annotated by BRENDA team
Srinivasan, V.; Sandhya, N.; Sampathkumar, R.; Farooq, S.; Mohan, V.; Balasubramanyam, M.
Glutamine fructose-6-phosphate amidotransferase (GFAT) gene expression and activity in patients with type 2 diabetes: inter-relationships with hyperglycaemia and oxidative stress
Clin. Biochem.
40
952-957
2007
Homo sapiens
Manually annotated by BRENDA team
Raczynska, J.; Olchowy, J.; Konariev, P.V.; Svergun, D.I.; Milewski, S.; Rypniewski, W.
The crystal and solution studies of glucosamine-6-phosphate synthase from Candida albicans
J. Mol. Biol.
372
672-688
2007
Candida albicans, Candida albicans (P53704)
Manually annotated by BRENDA team
Mouilleron, S.; Badet-Denisot, M.A.; Golinelli-Pimpaneau, B.
Ordering of C-terminal loop and glutaminase domains of glucosamine-6-phosphate synthase promotes sugar ring opening and formation of the ammonia channel
J. Mol. Biol.
377
1174-1185
2008
Escherichia coli, Escherichia coli (P17169)
Manually annotated by BRENDA team
Kalamorz, F.; Reichenbach, B.; Maerz, W.; Rak, B.; Goerke, B.
Feedback control of glucosamine-6-phosphate synthase GlmS expression depends on the small RNA GlmZ and involves the novel protein YhbJ in Escherichia coli
Mol. Microbiol.
65
1518-1533
2007
Escherichia coli
Manually annotated by BRENDA team
Nakaishi, Y.; Bando, M.; Shimizu, H.; Watanabe, K.; Goto, F.; Tsuge, H.; Kondo, K.; Komatsu, M.
Structural analysis of human glutamine:fructose-6-phosphate amidotransferase, a key regulator in type 2 diabetes
FEBS Lett.
583
163-167
2009
Homo sapiens, Homo sapiens (Q06210)
Manually annotated by BRENDA team
Luo, C.; Shao, W.; Li, X.; Chen, Z.; Liu, Y.
Molecular cloning, sequencing, and expression of a L-glutamine D-fructose 6-phosphate amidotransferase gene from Volvariella volvacea
Protein J.
28
34-43
2009
Volvariella volvacea (Q6DLZ8), Volvariella volvacea V1-1 (Q6DLZ8)
Manually annotated by BRENDA team
Valerio-Lepiniec, M.; Aumont-Nicaise, M.; Roux, C.; Raynal, B.; England, P.; Badet, B.; Badet-Denisot, M.A.; Desmadril, M.
Analysis of the Escherichia coli glucosamine-6-phosphate synthase activity by isothermal titration calorimetry and differential scanning calorimetry
Arch. Biochem. Biophys.
498
95-104
2010
Escherichia coli
Manually annotated by BRENDA team
Jedrzejczak, R.; Wojciechowski, M.; Andruszkiewicz, R.; Sowieski, P.; Kot-Wasik, A.; Milewski, S.
Inactivation of glucosamine-6-phosphate synthase by N3-oxoacyl derivatives of L-2,3-diaminopropanoic acid
ChemBioChem
13
85-96
2012
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Gong, B.; Klein, D.J.; Ferre-Damare, A.R.; Carey, P.R.
The glmS ribozyme tunes the catalytically critical pK(a) of its coenzyme glucosamine-6-phosphate
J. Am. Chem. Soc.
133
14188-14191
2011
Caldanaerobacter subterraneus subsp. tengcongensis
Manually annotated by BRENDA team
Mouilleron, S.; Badet-Denisot, M.A.; Pecqueur, L.; Madiona, K.; Assrir, N.; Badet, B.; Golinelli-Pimpaneau, B.
Structural basis for morpheein-type allosteric regulation of Escherichia coli glucosamine-6-phosphate synthase: equilibrium between inactive hexamer and active dimer
J. Biol. Chem.
287
34533-34546
2012
Escherichia coli, Escherichia coli (P17169)
Manually annotated by BRENDA team
Czarnecka, J.; Kwiatkowska, K.; Gabriel, I.; Wojciechowski, M.; Milewski, S.
Engineering Candida albicans glucosamine-6-phosphate synthase for efficient enzyme purification
J. Mol. Recognit.
25
564-570
2012
Candida albicans
Manually annotated by BRENDA team
Gaucher-Wieczorek, F.; Guerineau, V.; Touboul, D.; Thetiot-Laurent, S.; Pelissier, F.; Badet-Denisot, M.A.; Badet, B.; Durand, P.
Evaluation of synthase and hemisynthase activities of glucosamine-6-phosphate synthase by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry
Anal. Biochem.
458
61-65
2014
Escherichia coli (P17169)
Manually annotated by BRENDA team
Bennett, A.M.; Shippy, D.C.; Eakley, N.; Okwumabua, O.; Fadl, A.A.
Functional characterization of glucosamine-6-phosphate synthase (GlmS) in Salmonella enterica serovar Enteritidis
Arch. Microbiol.
198
541-549
2016
Salmonella enterica subsp. enterica serovar Enteritidis, Salmonella enterica subsp. enterica serovar Enteritidis E2627
Manually annotated by BRENDA team
Chen, Q.; Mueller, J.S.; Pang, P.C.; Laval, S.H.; Haslam, S.M.; Lochmueller, H.; Dell, A.
Global N-linked glycosylation is not significantly impaired in myoblasts in congenital myasthenic syndromes caused by defective glutamine-fructose-6-phosphate transaminase 1 (GFPT1)
Biomolecules
5
2758-2781
2015
Homo sapiens, Homo sapiens (Q06210)
Manually annotated by BRENDA team
Pawlak, D.; Schielmann, M.; Wojciechowski, M.; Andruszkiewicz, R.
Synthesis and biological activity of novel ester derivatives of N(3)-(4-metoxyfumaroyl)-(S)-2,3-diaminopropanoic acid containing amide and keto function as inhibitors of glucosamine-6-phosphate synthase
Bioorg. Med. Chem. Lett.
26
3586-3589
2016
Candida albicans, Candida albicans ATCC 10231
Manually annotated by BRENDA team
Wang, S.; Li, P.; Su, J.; Wu, X.; Liang, R.
Characterization and expression of glucosamine-6-phosphate synthase from Saccharomyces cerevisiae in Pichia pastoris
Biotechnol. Lett.
36
2023-2028
2014
Saccharomyces cerevisiae (P14742), Saccharomyces cerevisiae
Manually annotated by BRENDA team
Pawlak, D.; Stolarska, M.; Wojciechowski, M.; Andruszkiewicz, R.
Synthesis, anticandidal activity of N(3)-(4-methoxyfumaroyl)-(S)-2,3-diaminopropanoic amide derivatives - novel inhibitors of glucosamine-6-phosphate synthase
Eur. J. Med. Chem.
90
577-582
2015
Candida albicans
Manually annotated by BRENDA team
Hussein, S.; Kubba, A.; Abdula, A.
Docking study of some new 2, 5-disubstituted-1, 3, 4-thiadiazole derivatives against glucosamine-6-phosphate synthase
Int. J. Appl. Chem.
12
1-10
2016
Escherichia coli (P17169)
-
Manually annotated by BRENDA team
Sanchez-Lopez, J.F.; Gonzalez-Ibarra, J.; Alvarez-Vargas, A.; Milewski, S.; Villagomez-Castro, J.C.; Cano-Canchola, C.; Lopez-Romero, E.
Isolation of the GFA1 gene encoding glucosamine-6-phosphate synthase of Sporothrix schenckii and its expression in Saccharomyces cerevisiae
Protein Expr. Purif.
110
57-64
2015
Sporothrix schenckii (D3YIG6), Sporothrix schenckii
Manually annotated by BRENDA team