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Information on EC 2.6.1.106 - dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucose transaminase

for references in articles please use BRENDA:EC2.6.1.106
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IUBMB Comments
A pyridoxal-phosphate protein. The enzyme is involved in the biosynthesis of dTDP-alpha-D-desosamine, a sugar found in several bacterial macrolide antibiotics including erythromycin, megalomicin A, mycinamicin II, and oleandomycin. The reaction occurs in the reverse direction.
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The expected taxonomic range for this enzyme is: Streptomyces venezuelae
Synonyms
dTDP-3-dehydro-4,6-dideoxy-alpha-D-glucopyranose transaminase, DesV, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucose + 2-oxoglutarate = dTDP-3-dehydro-4,6-deoxy-alpha-D-glucose + L-glutamate
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