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(2E,6E)-farnesyl diphosphate + 6 isopentenyl diphosphate
6 diphosphate + all-trans-nonaprenyl diphosphate
(2E,6E)-farnesyl diphosphate + 6 isopentenyl diphosphate
6 diphosphate + nonaprenyl diphosphate
-
17% of the activity with geranylgeranyl diphosphate
-
-
?
dimethylallyl diphosphate + 8 isopentenyl diphosphate
8 diphosphate + all-trans-nonaprenyl diphosphate
geranyl diphosphate + 7 isopentenyl diphosphate
7 diphosphate + all-trans-nonaprenyl diphosphate
geranylgeranyl diphosphate + 5 isopentenyl diphosphate
5 diphosphate + all-trans-nonaprenyl diphosphate
additional information
?
-
(2E,6E)-farnesyl diphosphate + 6 isopentenyl diphosphate
6 diphosphate + all-trans-nonaprenyl diphosphate
At-SPS2 prefers geranylgeranyl diphosphate to farnesyl diphosphate as the allylic substrate
the main product is nonaprenyl diphosphate, considerable amounts of intermediates, such as geranylgeranyl diphosphate are formed
-
?
(2E,6E)-farnesyl diphosphate + 6 isopentenyl diphosphate
6 diphosphate + all-trans-nonaprenyl diphosphate
geranylgeranyl diphosphate is preferred over farnesyl diphosphate as allylic substrate
the main product is nonaprenyl diphosphate, considerable amounts of geranylgeranyl diphosphate are formed
-
?
(2E,6E)-farnesyl diphosphate + 6 isopentenyl diphosphate
6 diphosphate + all-trans-nonaprenyl diphosphate
-
-
-
?
dimethylallyl diphosphate + 8 isopentenyl diphosphate
8 diphosphate + all-trans-nonaprenyl diphosphate
-
-
-
?
dimethylallyl diphosphate + 8 isopentenyl diphosphate
8 diphosphate + all-trans-nonaprenyl diphosphate
low activity
-
-
?
geranyl diphosphate + 7 isopentenyl diphosphate
7 diphosphate + all-trans-nonaprenyl diphosphate
-
39% of the activity with geranylgeranyl diphosphate
-
-
?
geranyl diphosphate + 7 isopentenyl diphosphate
7 diphosphate + all-trans-nonaprenyl diphosphate
-
-
-
?
geranylgeranyl diphosphate + 5 isopentenyl diphosphate
5 diphosphate + all-trans-nonaprenyl diphosphate
-
-
-
?
geranylgeranyl diphosphate + 5 isopentenyl diphosphate
5 diphosphate + all-trans-nonaprenyl diphosphate
-
-
-
?
geranylgeranyl diphosphate + 5 isopentenyl diphosphate
5 diphosphate + all-trans-nonaprenyl diphosphate
-
-
-
?
geranylgeranyl diphosphate + 5 isopentenyl diphosphate
5 diphosphate + all-trans-nonaprenyl diphosphate
-
-
-
?
geranylgeranyl diphosphate + 5 isopentenyl diphosphate
5 diphosphate + all-trans-nonaprenyl diphosphate
At-SPS1 contributes to the biosynthesis of the plastoquinone side-chain in Arabidopsis thaliana
-
-
?
geranylgeranyl diphosphate + 5 isopentenyl diphosphate
5 diphosphate + all-trans-nonaprenyl diphosphate
At-SPS1 contributes to the biosynthesis of the ubiquinone side-chain in Arabidopsis thaliana
-
-
?
geranylgeranyl diphosphate + 5 isopentenyl diphosphate
5 diphosphate + all-trans-nonaprenyl diphosphate
At-SPS1 contributes to the biosynthesis of the ubiquinone side-chain in Arabidopsis thaliana
-
-
?
geranylgeranyl diphosphate + 5 isopentenyl diphosphate
5 diphosphate + all-trans-nonaprenyl diphosphate
At-SPS2 supplies the precursor of the plastoquinone side-chain in Arabidopsis thaliana
-
-
?
geranylgeranyl diphosphate + 5 isopentenyl diphosphate
5 diphosphate + all-trans-nonaprenyl diphosphate
At-SPS2 prefers geranylgeranyl diphosphate to farnesyl diphosphate as the allylic substrate
a large amount of nonaprenyl diphosphate is formed
-
?
geranylgeranyl diphosphate + 5 isopentenyl diphosphate
5 diphosphate + all-trans-nonaprenyl diphosphate
geranylgeranyl diphosphate is preferred over farnesyl diphosphate as allylic substrate
nonaprenyl diphosphate is almost exclusively formed
-
?
geranylgeranyl diphosphate + 5 isopentenyl diphosphate
5 diphosphate + all-trans-nonaprenyl diphosphate
-
geranylgeranyl diphosphate is the preferred allylic substrate
-
-
?
geranylgeranyl diphosphate + 5 isopentenyl diphosphate
5 diphosphate + all-trans-nonaprenyl diphosphate
-
enzyme SlSPS extends the prenyl chain length of the endogenous ubiquinone to nine isoprene units
-
-
?
geranylgeranyl diphosphate + 5 isopentenyl diphosphate
5 diphosphate + all-trans-nonaprenyl diphosphate
geranylgeranyl diphosphate is the preferred allylic substrate
-
-
?
geranylgeranyl diphosphate + 5 isopentenyl diphosphate
5 diphosphate + all-trans-nonaprenyl diphosphate
the enzyme is involved in synthesis of ubiquinone-9
-
-
?
additional information
?
-
no activity with dimethylallyl diphosphate and geranyl diphosphate, recombinant His6-tagged At-SPS2 fusion protein and truncated from of At-SPS2 (At-SPS2DELTA, in which the 30 N-terminal residues of the putative signal-peptide are removed and, instead the His6 tag is attached to the N-terminus)
-
-
?
additional information
?
-
no activity with dimethylallyl diphosphate and geranyl diphosphate, recombinant His6-tagged At-SPS2 fusion protein and truncated from of At-SPS2 (At-SPS2DELTA, in which the 30 N-terminal residues of the putative signal-peptide are removed and, instead the His6 tag is attached to the N-terminus)
-
-
?
additional information
?
-
-
no activity with dimethylallyl diphosphate and geranyl diphosphate, recombinant His6-tagged At-SPS2 fusion protein and truncated from of At-SPS2 (At-SPS2DELTA, in which the 30 N-terminal residues of the putative signal-peptide are removed and, instead the His6 tag is attached to the N-terminus)
-
-
?
additional information
?
-
no activity with farnesyl diphosphate and dimethylallyl diphosphate
-
-
?
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
dimethylallyl diphosphate + 8 isopentenyl diphosphate
8 diphosphate + all-trans-nonaprenyl diphosphate
-
-
-
?
geranylgeranyl diphosphate + 5 isopentenyl diphosphate
5 diphosphate + all-trans-nonaprenyl diphosphate
geranylgeranyl diphosphate + 5 isopentenyl diphosphate
5 diphosphate + all-trans-nonaprenyl diphosphate
-
-
-
?
geranylgeranyl diphosphate + 5 isopentenyl diphosphate
5 diphosphate + all-trans-nonaprenyl diphosphate
-
-
-
?
geranylgeranyl diphosphate + 5 isopentenyl diphosphate
5 diphosphate + all-trans-nonaprenyl diphosphate
-
-
-
?
geranylgeranyl diphosphate + 5 isopentenyl diphosphate
5 diphosphate + all-trans-nonaprenyl diphosphate
-
-
-
?
geranylgeranyl diphosphate + 5 isopentenyl diphosphate
5 diphosphate + all-trans-nonaprenyl diphosphate
At-SPS1 contributes to the biosynthesis of the plastoquinone side-chain in Arabidopsis thaliana
-
-
?
geranylgeranyl diphosphate + 5 isopentenyl diphosphate
5 diphosphate + all-trans-nonaprenyl diphosphate
At-SPS1 contributes to the biosynthesis of the ubiquinone side-chain in Arabidopsis thaliana
-
-
?
geranylgeranyl diphosphate + 5 isopentenyl diphosphate
5 diphosphate + all-trans-nonaprenyl diphosphate
At-SPS1 contributes to the biosynthesis of the ubiquinone side-chain in Arabidopsis thaliana
-
-
?
geranylgeranyl diphosphate + 5 isopentenyl diphosphate
5 diphosphate + all-trans-nonaprenyl diphosphate
At-SPS2 supplies the precursor of the plastoquinone side-chain in Arabidopsis thaliana
-
-
?
geranylgeranyl diphosphate + 5 isopentenyl diphosphate
5 diphosphate + all-trans-nonaprenyl diphosphate
the enzyme is involved in synthesis of ubiquinone-9
-
-
?
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0.00689 - 5.73
(2E,6E)-farnesyl diphosphate
0.00459 - 0.00512
farnesyl diphosphate
0.0548
geranyl diphosphate
pH 7.4, 37°C
0.000565 - 1.61
geranylgeranyl diphosphate
0.0192 - 151
isopentenyl diphosphate
0.00689
(2E,6E)-farnesyl diphosphate
pH 8.0, 30°C, truncated from of At-SPS2 (At-SPS2DELTA, in which the 30 N-terminal residues of the putative signal-peptide are removed and, instead the His6 tag is attached to the N-terminus)
5.73
(2E,6E)-farnesyl diphosphate
pH 8.0, 30°C
0.00459
farnesyl diphosphate
pH 7.4, 37°C
0.00512
farnesyl diphosphate
pH 8.0, 30°C, His6-tagged At-SPS2 fusion protein
0.000565
geranylgeranyl diphosphate
pH 8.0, 30°C, His6-tagged At-SPS2 fusion protein
0.000843
geranylgeranyl diphosphate
pH 8.0, 30°C, truncated from of At-SPS2 (At-SPS2DELTA, in which the 30 N-terminal residues of the putative signal-peptide are removed and, instead the His6 tag is attached to the N-terminus), truncated from of At-SPS2 (At-SPS2DELTA, in which the 30 N-terminal residues of the putative signal-peptide are removed and, instead the His6 tag is attached to the N-terminus)
0.00707
geranylgeranyl diphosphate
pH 7.4, 37°C
1.61
geranylgeranyl diphosphate
pH 8.0, 30°C
0.0192
isopentenyl diphosphate
pH 7.4, 37°C, cosubstrate: geranyl diphosphate
0.0243
isopentenyl diphosphate
pH 7.4, 37°C, cosubstrate: geranylgeranyl diphosphate
0.0289
isopentenyl diphosphate
pH 8.0, 30°C, cosubstrate: geranylgeranyl diphosphate, truncated from of At-SPS2 (At-SPS2DELTA, in which the 30 N-terminal residues of the putative signal-peptide are removed and, instead the His6 tag is attached to the N-terminus)
0.0307
isopentenyl diphosphate
pH 7.4, 37°C, cosubstrate: farnesyl diphosphate
0.0377
isopentenyl diphosphate
pH 8.0, 30°C, cosubstrate: geranylgeranyl diphosphate, His6-tagged At-SPS2 fusion protein
0.182
isopentenyl diphosphate
pH 8.0, 30°C, cosubstrate: farnesyl diphosphate, truncated from of At-SPS2 (At-SPS2DELTA, in which the 30 N-terminal residues of the putative signal-peptide are removed and, instead the His6 tag is attached to the N-terminus)
0.248
isopentenyl diphosphate
pH 8.0, 30°C, cosubstrate: farnesyl diphosphate, His6-tagged At-SPS2 fusion protein
20
isopentenyl diphosphate
pH 8.0, 30°C, cosubstrate: geranylgeranyl diphosphate
151
isopentenyl diphosphate
pH 8.0, 30°C, cosubstrate: farnesyl diphosphate
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
0.032 - 3.77
(2E,6E)-farnesyl diphosphate
29.7
farnesyl diphosphate
pH 8.0, 30°C
0.065
geranyl diphosphate
pH 7.4, 37°C
0.087 - 21
geranylgeranyl diphosphate
0.043 - 15
isopentenyl diphosphate
0.032
(2E,6E)-farnesyl diphosphate
pH 7.4, 37°C
3.77
(2E,6E)-farnesyl diphosphate
pH 8.0, 30°C, truncated from of At-SPS2 (At-SPS2DELTA, in which the 30 N-terminal residues of the putative signal-peptide are removed and, instead the His6 tag is attached to the N-terminus)
0.087
geranylgeranyl diphosphate
pH 7.4, 37°C
2.33
geranylgeranyl diphosphate
pH 8.0, 30°C, truncated from of At-SPS2 (At-SPS2DELTA, in which the 30 N-terminal residues of the putative signal-peptide are removed and, instead the His6 tag is attached to the N-terminus), truncated from of At-SPS2 (At-SPS2DELTA, in which the 30 N-terminal residues of the putative signal-peptide are removed and, instead the His6 tag is attached to the N-terminus)
21
geranylgeranyl diphosphate
pH 8.0, 30°C
0.043
isopentenyl diphosphate
pH 7.4, 37°C, cosubstrate: farnesyl diphosphate
0.131
isopentenyl diphosphate
pH 7.4, 37°C, cosubstrate: geranyl diphosphate
0.217
isopentenyl diphosphate
pH 7.4, 37°C, cosubstrate: geranylgeranyl diphosphate
1.72
isopentenyl diphosphate
pH 8.0, 30°C, cosubstrate: geranylgeranyl diphosphate, truncated from of At-SPS2 (At-SPS2DELTA, in which the 30 N-terminal residues of the putative signal-peptide are removed and, instead the His6 tag is attached to the N-terminus)
2.83
isopentenyl diphosphate
pH 8.0, 30°C, cosubstrate: farnesyl diphosphate, truncated from of At-SPS2 (At-SPS2DELTA, in which the 30 N-terminal residues of the putative signal-peptide are removed and, instead the His6 tag is attached to the N-terminus)
14.7
isopentenyl diphosphate
pH 8.0, 30°C, cosubstrate: farnesyl diphosphate
15
isopentenyl diphosphate
pH 8.0, 30°C, cosubstrate: geranylgeranyl diphosphate
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
0.00701 - 547
(2E,6E)-farnesyl diphosphate
0.00119
geranyl diphosphate
pH 7.4, 37°C
0.012 - 2770
geranylgeranyl diphosphate
0.0014 - 595
isopentenyl diphosphate
0.00701
(2E,6E)-farnesyl diphosphate
pH 7.4, 37°C
5.19
(2E,6E)-farnesyl diphosphate
pH 8.0, 30°C
547
(2E,6E)-farnesyl diphosphate
pH 8.0, 30°C, truncated from of At-SPS2 (At-SPS2DELTA, in which the 30 N-terminal residues of the putative signal-peptide are removed and, instead the His6 tag is attached to the N-terminus)
0.012
geranylgeranyl diphosphate
pH 7.4, 37°C
13.1
geranylgeranyl diphosphate
pH 8.0, 30°C
2770
geranylgeranyl diphosphate
pH 8.0, 30°C, truncated from of At-SPS2 (At-SPS2DELTA, in which the 30 N-terminal residues of the putative signal-peptide are removed and, instead the His6 tag is attached to the N-terminus), truncated from of At-SPS2 (At-SPS2DELTA, in which the 30 N-terminal residues of the putative signal-peptide are removed and, instead the His6 tag is attached to the N-terminus)
0.0014
isopentenyl diphosphate
pH 7.4, 37°C, cosubstrate: farnesyl diphosphate
0.00685
isopentenyl diphosphate
pH 7.4, 37°C, cosubstrate: geranyl diphosphate
0.00893
isopentenyl diphosphate
pH 7.4, 37°C, cosubstrate: geranylgeranyl diphosphate
0.0968
isopentenyl diphosphate
pH 8.0, 30°C, cosubstrate: farnesyl diphosphate
0.752
isopentenyl diphosphate
pH 8.0, 30°C, cosubstrate: geranylgeranyl diphosphate
15.5
isopentenyl diphosphate
pH 8.0, 30°C, cosubstrate: farnesyl diphosphate, truncated from of At-SPS2 (At-SPS2DELTA, in which the 30 N-terminal residues of the putative signal-peptide are removed and, instead the His6 tag is attached to the N-terminus)
595
isopentenyl diphosphate
pH 8.0, 30°C, cosubstrate: geranylgeranyl diphosphate, truncated from of At-SPS2 (At-SPS2DELTA, in which the 30 N-terminal residues of the putative signal-peptide are removed and, instead the His6 tag is attached to the N-terminus)
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
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evolution
co-expression network of the Arabidopsis thaliana solanesyl-diphosphate synthase family
malfunction
in contrast to other plastochromanol-8 biosynthetic mutants, neither the single atsps knock-outs nor the atsps1 atsps2 double knock-out display any defects in tocopherols accumulation or germination
malfunction
knockout of genes AtSPS1 and AtSPS2 causes a reduction in plastoquinone-9 content in leaves, and the leaves exhibit light suppression of photosynthetic system II under high-intensity light
malfunction
leaves of the atsps2 knock-out are devoid of plastochromanol-8 and display severe losses of both non-photoactive and photoactive plastoquinone-9, resulting in near complete photoinhibition at high light intensity. The photoinhibition is paralleled by significant damage to photosystem II but not to photosystem I. In contrast to other plastochromanol-8 biosynthetic mutants, neither the single atsps knock-outs nor the atsps1 atsps2 double knock-out display any defects in tocopherols accumulation or germination
malfunction
-
plants silenced for SlSPS are photobleached and accumulate phytoene
malfunction
RNAi-mediated depletion of TbSPPS leads to severe growth inhibition. Ablation of TbSPPS by RNAi will decrease the function of the glycerol-3-phosphate shuttle, which is cured by application of glycerol. The viability of the BSF cells is compromised upon RNAi induction, phenotype overview. Addition of ubiquinone to the medium alleviates the effect of RNAi-mediated depletion of TbSPPS
metabolism
FBN5-B is required for plastoquinone-9 biosynthesis through its interaction with enzyme SPS
metabolism
-
requirement for two long-chain prenyl diphosphate synthases in the tomato, i.e. SlSPS and SlDPS, a decaprenyl diphosphate synthase, EC 2.5.1.86
metabolism
the enzyme is involved in the biosynthesis of solanesyl diphosphate and plastoquinone-9
metabolism
the enzyme is involved in the biosynthesis of solanesyl diphosphate and plastoquinone-9. FBN5-B is required for plastoquinone-9 biosynthesis through its interaction with enzyme SPS
metabolism
the enzyme interacts with the plastid lipid binding protein fibrillin5 for synthesis of the solanesyl diphosphate tail in plastoquinone-9
metabolism
-
FBN5-B is required for plastoquinone-9 biosynthesis through its interaction with enzyme SPS
-
metabolism
-
the enzyme is involved in the biosynthesis of solanesyl diphosphate and plastoquinone-9
-
metabolism
-
the enzyme is involved in the biosynthesis of solanesyl diphosphate and plastoquinone-9. FBN5-B is required for plastoquinone-9 biosynthesis through its interaction with enzyme SPS
-
physiological function
Arabidopsis thaliana SPS1-overexpressing lines are much more resistant to photooxidative stress than the wild-type, showing marked decreases in leaf bleaching, lipid peroxidation and PSII photoinhibition under excess light. Comparison of the SPS1 overexpressors with other prenyl quinone mutants indicates that the enhanced phototolerance of the former plants is directly related to their increased capacities for plastoquinone-9 biosynthesis, phenotype, overview
physiological function
-
enzyme SlSPS is necessary for normal chloroplast structure and function
physiological function
plastid isoforms of solanesyl-diphosphate synthase catalyze the elongation of the prenyl side chain involved in the plastoquinone-9 and plastochromanol-8 biosynthesis, plastochromanol-8 originates from a subfraction of the non-photoactive pool of plastoquinone-9
physiological function
solanesyl diphosphate synthase is an enzyme of the ubiquinone synthetic pathway required throughout the life cycle of Trypanosoma brucei
physiological function
-
solanesyl diphosphate synthase, Sps, is a key enzyme in the metabolic pathways of solanesol and plastoquinone biosynthesis
physiological function
solanesyl diphosphate synthase, Sps, is a key enzyme in the metabolic pathways of solanesol and plastoquinone biosynthesis
physiological function
-
Arabidopsis thaliana SPS1-overexpressing lines are much more resistant to photooxidative stress than the wild-type, showing marked decreases in leaf bleaching, lipid peroxidation and PSII photoinhibition under excess light. Comparison of the SPS1 overexpressors with other prenyl quinone mutants indicates that the enhanced phototolerance of the former plants is directly related to their increased capacities for plastoquinone-9 biosynthesis, phenotype, overview
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
SPS1_ARATH
406
0
44468
Swiss-Prot
Chloroplast (Reliability: 5)
NPPPS_MYCTU
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
335
0
35560
Swiss-Prot
-
SPS2_ARATH
417
0
46045
Swiss-Prot
Chloroplast (Reliability: 3)
SPS3_ARATH
422
0
46401
Swiss-Prot
Mitochondrion (Reliability: 2)
A0A2H9ZV36_9ASPA
93
0
10770
TrEMBL
other Location (Reliability: 3)
A0A5B7ALR6_DAVIN
219
0
24003
TrEMBL
Secretory Pathway (Reliability: 3)
A0A2I0AV43_9ASPA
93
0
10889
TrEMBL
other Location (Reliability: 3)
A0A2I0AIC1_9ASPA
623
0
71908
TrEMBL
other Location (Reliability: 5)
U5DMZ8_9CHRO
323
0
35265
TrEMBL
-
A0A2I0AZ11_9ASPA
107
0
12445
TrEMBL
Secretory Pathway (Reliability: 4)
A0A2I0AX06_9ASPA
179
0
20450
TrEMBL
other Location (Reliability: 1)
A0A2G9HY61_9LAMI
421
0
46441
TrEMBL
Mitochondrion (Reliability: 2)
A0A6J4KNN4_9CYAN
uncultured Leptolyngbya sp
323
0
35480
TrEMBL
-
A0A2I0A5Y1_9ASPA
199
0
22415
TrEMBL
other Location (Reliability: 5)
A0A2G9G967_9LAMI
316
0
35454
TrEMBL
other Location (Reliability: 5)
A0A1G4G3I9_9BACT
324
0
36501
TrEMBL
-
A0A5B7CD13_DAVIN
524
0
58451
TrEMBL
other Location (Reliability: 3)
A0A3Q8IA74_LEIDO
359
0
39041
TrEMBL
Mitochondrion (Reliability: 2)
A0A2I0A351_9ASPA
93
0
10803
TrEMBL
other Location (Reliability: 3)
A0A2I0AK16_9ASPA
199
0
22090
TrEMBL
other Location (Reliability: 2)
A0A2I0B481_9ASPA
174
0
19834
TrEMBL
other Location (Reliability: 1)
A0A2I0AFP0_9ASPA
196
0
22209
TrEMBL
Mitochondrion (Reliability: 3)
A0A2H9ZRM9_9ASPA
195
0
21817
TrEMBL
other Location (Reliability: 5)
A0A2I0AE87_9ASPA
93
0
10656
TrEMBL
other Location (Reliability: 3)
A0A087C4Y4_9BIFI
324
0
35714
TrEMBL
-
A0A086CGW8_9CHRO
323
0
35837
TrEMBL
-
A0A2H9ZUD5_9ASPA
99
0
11699
TrEMBL
other Location (Reliability: 2)
A0A2I0A4V6_9ASPA
188
0
21503
TrEMBL
Mitochondrion (Reliability: 4)
A0A1G4I7J5_TRYEQ
359
0
39253
TrEMBL
Mitochondrion (Reliability: 5)
A0A2I0BAA3_9ASPA
174
0
18746
TrEMBL
Chloroplast (Reliability: 3)
A0A072UQ86_MEDTR
417
0
46088
TrEMBL
Mitochondrion (Reliability: 2)
A0A5B7C0P0_DAVIN
744
0
82437
TrEMBL
other Location (Reliability: 1)
A0A2I0ANN3_9ASPA
195
0
21893
TrEMBL
other Location (Reliability: 2)
A0A5B7BWM1_DAVIN
402
0
43965
TrEMBL
other Location (Reliability: 5)
A0A088RLX1_9TRYP
359
0
39376
TrEMBL
Mitochondrion (Reliability: 5)
A0A2K8WN78_9CHRO
323
0
35543
TrEMBL
-
A0A2I0AXE3_9ASPA
107
0
11992
TrEMBL
Secretory Pathway (Reliability: 4)
A0A2I0ABF8_9ASPA
134
0
15013
TrEMBL
Secretory Pathway (Reliability: 4)
A0A2I0BHE0_9ASPA
110
0
12461
TrEMBL
other Location (Reliability: 4)
A0A2G9GUN9_9LAMI
423
0
46170
TrEMBL
Mitochondrion (Reliability: 2)
A0A2I0B7S0_9ASPA
130
0
14902
TrEMBL
Secretory Pathway (Reliability: 2)
A0A5B7ALG0_DAVIN
423
0
46505
TrEMBL
other Location (Reliability: 3)
A0A2H9ZU38_9ASPA
200
0
22903
TrEMBL
Mitochondrion (Reliability: 5)
A0A5B7AQD6_DAVIN
421
0
46157
TrEMBL
other Location (Reliability: 5)
Q38EX7_TRYB2
Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
359
0
39253
TrEMBL
-
Q964Q8_TRYCR
363
0
39373
TrEMBL
-
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expression in Escherichia coli
-
expression in Escherichia coli, His6-tagged At-SPS2 fusion protein and the truncated from of At-SPS2 (At-SPS2DELTA, in which the 30 N-terminal residues of the putative signal-peptide are removed and, instead the His6 tag is attached to the N-terminus)
expression of TcSPPS is able to complement an Escherichia coli ispB mutant
gene AtSPS1, overexpressing of the plastoquinone-9 biosynthesis gene SPS1 in Arabidopsis thaliana generating plants that specifically accumulate plastoquinone-9 and its derivative plastochromanol-8
gene AtSPS1, phylogenetic analysis, recombinant expression of N-terminally GST-tagged enzyme in Nicotiana benthamiana epidermis cell endoplasmic reticulum using Agrobacterium tumefaciens strain C58C1 for transfection
gene AtSPS2, phylogenetic analysis, recombinant expression of N-terminally GST-tagged enzyme in Nicotiana benthamiana leaf chloroplasts using Agrobacterium tumefaciens strain C58C1 for transfection
gene SlSPS, constitutive overexpression of SlSPS in immature tobacco leaves elevates the plastoquinone content in the leaves
-
gene SlSPS, recombinant expression in Escherichia coli. In planta, constitutive overexpression of SlSPS elevates the plastoquinone content of immature tobacco leaves
-
heterologous expression of either SPS1 allows the generation of UQ-9 in a decaprenyl diphosphate synthase-defective strain of fission yeast and also in wild-type Escherichia coli
heterologous expression of SPS1 allows the generation of UQ-9 in a decaprenyl diphosphate synthase-defective strain of fission yeast and also in wild-type Escherichia coli
heterologously expressed in Escherichia coli as as His6-tagged fusion protein
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Hirooka, K.; Bamba, T.; Fukusaki, E.I.; Kobayashi, A.
Cloning and kinetic characterization of Arabidopsis thaliana solanesyl diphosphate synthase
Biochem. J.
370
679-686
2003
Arabidopsis thaliana (Q8S948)
brenda
Hirooka, K.; Izumi, Y.; An, C.I.; Nakazawa, Y.; Fukusaki, E.; Kobayashi, A.
Functional analysis of two solanesyl diphosphate synthases from Arabidopsis thaliana
Biosci. Biotechnol. Biochem.
69
592-601
2005
Arabidopsis thaliana (Q76FS5), Arabidopsis thaliana (Q8S948), Arabidopsis thaliana
brenda
Jun, L.; Saiki, R.; Tatsumi, K.; Nakagawa, T.; Kawamukai, M.
Identification and subcellular localization of two solanesyl diphosphate synthases from Arabidopsis thaliana
Plant Cell Physiol.
45
1882-1888
2004
Arabidopsis thaliana (Q76FS5), Arabidopsis thaliana (Q8S948)
brenda
Ferella, M.; Montalvetti, A.; Rohloff, P.; Miranda, K.; Fang, J.; Reina, S.; Kawamukai, M.; Bua, J.; Nilsson, D.; Pravia, C.; Katzin, A.; Cassera, M.B.; Aslund, L.; Andersson, B.; Docampo, R.; Bontempi, E.J.
A solanesyl-diphosphate synthase localizes in glycosomes of Trypanosoma cruzi
J. Biol. Chem.
281
39339-39348
2006
Trypanosoma cruzi (Q964Q8), Trypanosoma cruzi
brenda
Phatthiya, A.; Takahashi, S.; Chareonthiphakorn, N.; Koyama, T.; Wititsuwannakul, D.; Wititsuwannakul, R.
Cloning and expression of the gene encoding solanesyl diphosphate synthase from Hevea brasiliensis
Plant Sci.
172
824-831
2007
Hevea brasiliensis
brenda
Jones, M.; Perez-Fons, L.; Robertson, F.; Bramley, P.; Fraser, P.
Functional characterization of long-chain prenyl diphosphate synthases from tomato
Biochem. J.
449
729-740
2013
Solanum lycopersicum
brenda
Lai, D.H.; Bontempi, E.J.; Lukes, J.
Trypanosoma brucei solanesyl-diphosphate synthase localizes to the mitochondrion
Mol. Biochem. Parasitol.
183
189-192
2012
Trypanosoma brucei (Q38EX7)
brenda
Lai, D.H.; Poropat, E.; Pravia, C.; Landoni, M.; Couto, A.S.; Rojo, F.G.; Fuchs, A.G.; Dubin, M.; Elingold, I.; Rodriguez, J.B.; Ferella, M.; Esteva, M.I.; Bontempi, E.J.; Lukes, J.
Solanesyl diphosphate synthase, an enzyme of the ubiquinone synthetic pathway, is required throughout the life cycle of Trypanosoma brucei
Eukaryot. Cell
13
320-328
2014
Trypanosoma brucei (Q38EX7), Trypanosoma brucei
brenda
Block, A.; Fristedt, R.; Rogers, S.; Kumar, J.; Barnes, B.; Barnes, J.; Elowsky, C.G.; Wamboldt, Y.; Mackenzie, S.A.; Redding, K.; Merchant, S.S.; Basset, G.J.
Functional modeling identifies paralogous solanesyl-diphosphate synthases that assemble the side chain of plastoquinone-9 in plastids
J. Biol. Chem.
288
27594-27606
2013
Arabidopsis thaliana (Q76FS5), Arabidopsis thaliana (Q8S948)
brenda
Yan, N.; Liu, Y.; Gong, D.; Du, Y.; Zhang, H.; Zhang, Z.
Solanesol: a review of its resources, derivatives, bioactivities, medicinal applications, and biosynthesis
Phytochem. Rev.
14
403-417
2015
Solanum lycopersicum, Arabidopsis thaliana (Q76FS5), Arabidopsis thaliana (Q8S948)
-
brenda
Kim, E.H.; Lee, Y.; Kim, H.U.
Fibrillin 5 is essential for plastoquinone-9 biosynthesis by binding to solanesyl diphosphate synthases in Arabidopsis
Plant Cell
27
2956-2971
2015
Arabidopsis thaliana (Q76FS5), Arabidopsis thaliana (Q8S948), Arabidopsis thaliana Col-0 (Q76FS5), Arabidopsis thaliana Col-0 (Q8S948)
brenda
Ksas, B.; Becuwe, N.; Chevalier, A.; Havaux, M.
Plant tolerance to excess light energy and photooxidative damage relies on plastoquinone biosynthesis
Sci. Rep.
5
10919
2015
Arabidopsis thaliana (Q8S948), Arabidopsis thaliana Col-0 (Q8S948)
brenda
Kim, E.H.; Lee, D.W.; Lee, K.R.; Jung, S.J.; Jeon, J.S.; Kim, H.U.
Conserved function of fibrillin5 in the plastoquinone-9 biosynthetic pathway in Arabidopsis and rice
Front. Plant Sci.
8
1197
2017
Arabidopsis thaliana (Q76FS5), Arabidopsis thaliana (Q8S948)
brenda
Kahlau, S.; Schroeder, F.; Freigang, J.; Laber, B.; Lange, G.; Passon, D.; Kleessen, S.; Lohse, M.; Schulz, A.; von Koskull-Doering, P.; Klie, S.; Gille, S.
Aclonifen targets solanesyl diphosphate synthase, representing a novel mode of action for herbicides
Pest Manag. Sci.
76
3377-3388
2020
Arabidopsis thaliana (Q76FS5), Arabidopsis thaliana (Q8S948)
brenda