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Information on EC 2.5.1.141 - heme o synthase

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IUBMB Comments
The enzyme, found in many archaea, bacteria, and eukaryotes, produces heme o, which in many cases is further modified into heme a. In organisms that produce heme a, the enzyme forms a complex with heme a synthase. In some archaeal species the enzyme transfers a geranylgeranyl group instead of a farnesyl group.
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Word Map
The expected taxonomic range for this enzyme is: Bacteria, Eukaryota
Synonyms
caaE, Cox10, coxD, CtaB, cyoE, CyoE protein, heme A:farnesyltransferase, heme B farnesyltransferase, heme o synthase, HOS, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
(2E,6E)-farnesyl diphosphate + protoheme IX + H2O = diphosphate + ferroheme o
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