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Information on EC 2.5.1.106 - tryprostatin B synthase

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IUBMB Comments
The enzyme from the fungus Aspergillus fumigatus can also prenylate other tryptophan-containing cyclic dipeptides. Prenylation occurs mainly at C-2 , but also at C-3 . Involved in the biosynthetic pathways of several indole alkaloids such as tryprostatins, cyclotryprostatins, spirotryprostatins, fumitremorgins and verruculogen.
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Word Map
The expected taxonomic range for this enzyme is: Aspergillus fumigatus
Synonyms
brevianamide F prenyltransferase, FtmPT1, indole prenyltransferase, tryprostatin B synthase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
dimethylallyl diphosphate + brevianamide F = diphosphate + tryprostatin B
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