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Information on EC 2.4.2.54 - beta-ribofuranosylphenol 5'-phosphate synthase

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EC Tree
     2 Transferases
         2.4 Glycosyltransferases
             2.4.2 Pentosyltransferases
                2.4.2.54 beta-ribofuranosylphenol 5'-phosphate synthase
IUBMB Comments
The enzyme is involved in biosynthesis of tetrahydromethanopterin in archaea. It was initially thought to use 4-aminobenzoate as a substrate, but was later shown to utilize 4-hydroxybenzoate . The activity is dependent on Mg2+ or Mn2+ .
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Word Map
The expected taxonomic range for this enzyme is: Archaea, Bacteria
Synonyms
rfap synthase, beta-rfap synthase, beta-rfa-p synthase, ribofuranosylaminobenzene 5'-phosphate synthase, mth0830, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
5-phospho-alpha-D-ribose 1-diphosphate + 4-hydroxybenzoate = 4-(beta-D-ribofuranosyl)phenol 5'-phosphate + CO2 + diphosphate
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