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Information on EC 2.4.1.87 - N-acetyllactosaminide 3-alpha-galactosyltransferase

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EC Tree
     2 Transferases
         2.4 Glycosyltransferases
             2.4.1 Hexosyltransferases
                2.4.1.87 N-acetyllactosaminide 3-alpha-galactosyltransferase
IUBMB Comments
Acts on beta-galactosyl-1,4-N-acetylglucosaminyl termini on asialo-alpha1-acid glycoprotein and N-acetyllactosamine (beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosamine), but not on 2'-fucosylated-N-acetyllactosamine. The non-reducing terminal N-acetyllactosamine residues of glycoproteins can also act as acceptor. Now includes EC 2.4.1.124 and EC 2.4.1.151.
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Word Map
The expected taxonomic range for this enzyme is: Eukaryota, Bacteria, Archaea
Synonyms
alpha(1,3)GT, alpha-1,3-galactosyltransferase, alpha-1,3galactosyltransferase, alpha-D-galactosyltransferase, alpha-galactosyltransferase, alpha1,3-galactosyltransferase, alpha1,3-GalT, alpha1,3galactosyltransferase, alpha1,3GalT, alpha1,3GT, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
UDP-alpha-D-galactose + beta-D-galactosyl-(1->4)-beta-N-acetyl-D-glucosaminyl-R = UDP + alpha-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-N-acetylglucosaminyl-R (where R can be OH, an oligosaccharide or a glycoconjugate)
show the reaction diagram
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