Reference on EC 2.4.1.83 - dolichyl-phosphate beta-D-mannosyltransferase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Riedell, W.E.; Miernyk, J.A.
Glycoprotein synthesis in maize endosperm cells. The nucleoside diphosphate-sugar:dolichol-phosphate glycosyltransferase
Plant Physiol.
87
420-426
1988
Zea mays
Babczinski, P.; Haselbeck, A.; Tanner, W.
Yeast mannosyl transferases requiring dolichyl phosphate and dolichyl phosphate mannose as substrate. Partial purification and characterization of the solubilized enzyme
Eur. J. Biochem.
105
509-515
1980
Saccharomyces cerevisiae
Palamarczyk, G.; Lehle, L.; Mankowski, T.; Chojnacki, T.; Tanner, W.
Specificity of solubilized yeast glycosyl transferases for polyprenyl derivatives
Eur. J. Biochem.
105
517-523
1980
Saccharomyces cerevisiae
Haselbeck, A.
Purification of GDP mannose:dolichyl-phosphate O-beta-D-mannosyltransferase from Saccharomyces cerevisiae
Eur. J. Biochem.
181
663-668
1989
Saccharomyces cerevisiae
Bretthauer, R.K.; Wu, S.; Irwin, W.E.
Enzymatic transfer of mannose from guanosine diphosphate mannose to dolichol phosphate in yeast (Hansenula holstii). A possible step in mannan synthesis
Biochim. Biophys. Acta
304
736-747
1973
Nakazawaea holstii
Richards, J.B.; Hemming, F.W.
The transfer of mannose from guanosine diphosphate mannose to dolichol phosphate and protein by pig liver endoplasmic reticulum
Biochem. J.
130
77-93
1972
Sus scrofa
Jensen, J.W.; Schutzbach, J.S.
Characterization of mannosyl-transfer reactions catalyzed by dolichyl-mannosyl-phosphate-synthase
Carbohydr. Res.
149
199-208
1986
Rattus norvegicus
Jensen, J.W.; Schutzbach, J.S.
Activation of dolichyl-phospho-mannose synthase by phospholipids
Eur. J. Biochem.
153
41-48
1985
Rattus norvegicus
Gasnier, F.; Rousson, R.; Lerme, F.; Vaganay, E.; Louisot, P.; Gateau-Roesch, O.
Mitochondrial dolichyl-phosphate mannose synthase. Purification and immunogold localization by electron microscopy
Eur. J. Biochem.
206
853-858
1992
Mus musculus
Gasnier, F.; Louisot, P.; Gateau-Roesch, O.
Topological orientation of mitochondrial GDPmannose: dolichyl-monophosphate mannosyltransferase in the outer membrane
Biochim. Biophys. Acta
980
339-347
1989
Mus musculus
Kruszewska, J.; Palamarczyk, G.; Kubicek, C.P.
Mannosyl-phospho-dolichol synthase from Trichoderma reesei is activated by protein kinase dependent phosphorylation in vitro
FEMS Microbiol. Lett.
80
81-86
1991
Trichoderma reesei, Trichoderma reesei QM 9414
-
McDowell, W.; Schwarz, R.T.
Specificity of GDP-Man:dolichyl-phosphate mannosyltransferase for the guanosine diphosphate esters of mannose analogues containing deoxy and deoxyfluoro substituents
FEBS Lett.
243
413-416
1989
Gallus gallus
Gasnier, F.; Morelis, R.; Louisot, P.; Gateau, O.
Purification and properties of a mannosyltransferase solubilized from mitochondrial outer membranes
Biochim. Biophys. Acta
925
297-304
1987
Mus musculus
Tomita, Y.; Motokawa, Y.
GDPmannose dolicholphosphate mannosyltransferase of chicken liver mitochondria
Biochim. Biophys. Acta
842
176-183
1985
Gallus gallus
Carlo, P.L.; Villemez, C.L.
Solubilization and properties of polyprenyl phosphate: GDP-D-mannose mannosyl transferase
Arch. Biochem. Biophys.
198
117-123
1979
Acanthamoeba castellanii
Wilson, I.B.H.; Taylor, J.P.; Webberley, M.C.; Turner, N.J.; Flitsch, S.L.
A novel mono-branched lipid phosphate acts as a substrate for dolichyl phosphate mannose synthetase
Biochem. J.
295
195-201
1993
Saccharomyces cerevisiae
-
Schutzbach, J.S.; Zimmerman, J.W.; Forsee, W.T.
The purification and characterization of recombinant yeast dolichyl-phosphate-mannose synthase. Site-directed mutagenesis of the putative dolichol recognition sequence
J. Biol. Chem.
268
24190-24196
1993
Saccharomyces cerevisiae
Banerjee, D.K.; Kousvelari, E.E.; Baum, B.J.
cAMP-mediated protein phosphorylation of microsomal membranes increases mannosylphosphodolichol synthase activity
Proc. Natl. Acad. Sci. USA
84
6389-6393
1987
Rattus norvegicus
Colussi, P.A.; Taron, C.H.; Mack, J.C.; Orlean, P.
Human and Saccharomyces cerevisiae dolichol phosphate mannose synthases represent two classes of the enzyme, but both function in Schizosaccharomyces pombe
Proc. Natl. Acad. Sci. USA
94
7873-7878
1997
Saccharomyces cerevisiae, Homo sapiens (O60762), Homo sapiens
Maeda, Y.; Tanaka, S.; Hino, J.; Kangawa, K.; Kinoshita, T.
Human dolichol-phosphate-mannose synthase consists of three subunits, DPM1, DPM2 and DPM3
EMBO J.
19
2475-2482
2000
Homo sapiens
Xing, J.; Forsee, W.T.; Lamani, E.; Maltsev, S.D.; Danilov, L.L.; Shibaev, V.N.; Schutzbach, J.S.; Cheung, H.C.; Jedrzejas, M.J.
Investigations of the active site of Saccharomyces cerevisiae dolichyl-phosphate-mannose synthase using fluorescent labeled dolichyl-phosphate derivatives
Biochemistry
39
7886-7894
2000
Saccharomyces cerevisiae
Villagomez-Castro, J.C.; Calvo-Mendez, C.; Flores-Carreon, A.; Lopez-Romero, E.
Partial purification and characterization of dolichol phosphate mannose synthase from Entamoeba histolytica
Glycobiology
10
1311-1316
2000
Entamoeba histolytica
Tempone, A.J.; Furtado, D.R.; Gimba, E.R.T.; Oliveira, F.M.B.; Rumjanek, F.D.
Dolichol phosphate mannose synthase is differentially expressed in male and female worms of Schistosoma mansoni
Comp. Biochem. Physiol. B
131B
465-474
2002
Schistosoma mansoni
-
Zimmerman, J.W.; Robbins, P.W.
The hydrophobic domain of dolichyl-phosphate-mannose synthase is not essential for enzyme activity or growth in Saccharomyces cerevisiae
J. Biol. Chem.
268
16746-16753
1993
Saccharomyces cerevisiae
Mazhari-Tabrizi, R.; Eckert, V.; Blank, M.; Mueller, R.; Mumberg, D.; Funk, M.; Schwarz, R.T.
Cloning and functional expression of glycosyltransferases from parasitic protozoans by heterologous complementation in yeast: the dolichol phosphate mannose synthase from Trypanosoma brucei brucei
Biochem. J.
316
853-858
1996
Trypanosoma brucei brucei
-
Arroyo-Flores, B.L.; Calvo-Mendez, C.; Flores-Carreon, A.; Lopez-Romero, E.
Biosynthesis of glycoproteins in Candida albicans: solubilization and partial characterization of dolichol phosphate mannose synthase and protein mannosyl transferases
Antonie van Leeuwenhoek
73
289-297
1998
Candida albicans
Villagomez-Castro, J.C.; Calvo-Mendez, C.; Vargas-Rodriguez, L.; Flores-Carreon, A.; Lopez-Romero, E.
Entamoeba histolytica: solubilization and biochemical characterization of dolichol phosphate mannose synthase, an essential enzyme in glycoprotein biosynthesis
Exp. Parasitol.
88
111-120
1998
Entamoeba histolytica
Arroyo-Flores, B.L.; Calvo-Mendez, C.; Flores-Carreon, A.; Lopez-Romero, E.
Biosynthesis of glycoproteins in Candida albicans: activity of dolichol phosphate mannose synthase and protein mannosylation in a mixed membrane fraction
Microbiology
141
2289-2294
1995
Candida albicans
-
Kruszewska, J.; Kubicek, C.P.; Palamarczyk, G.
Modulation of mannosylphosphodolichol synthase and dolichol kinase activity in Trichoderma, related to protein secretion
Acta Biochim. Pol.
41
331-337
1994
Trichoderma reesei
Kruszewska, J.S.; Perlinska-Lenart, U.; Palamarczyk, G.
Solubilization and one-step purification of mannosylphosphodolichol synthase from Trichoderma reesei
Acta Biochim. Pol.
43
397-401
1996
Trichoderma reesei
Zhu, B.C.; Laine, R.A.
Dolichyl-phosphomannose synthase from the archae Thermoplasma acidophilum
Glycobiology
6
811-816
1996
Thermoplasma acidophilum
Forsee, W.T.; McPherson, D.; Schutzbach, J.S.
Characterization of recombinant yeast dolichyl mannosyl phosphate synthase and site-directed mutagenesis of its cysteine residues
Eur. J. Biochem.
244
953-958
1997
Saccharomyces cerevisiae
Janik, A.; Sosnowska, M.; Kruszewska, J.; Krotkiewski, H.; Lehle, L.; Palamarczyk, G.
Overexpression of GDP-mannose pyrophosphorylase in Saccharomyces cerevisiae corrects defects in dolichol-linked saccharide formation and protein glycosylation
Biochim. Biophys. Acta
1621
22-30
2003
Saccharomyces cerevisiae
Pu, L.; Scocca, J.R.; Walker, B.K.; Krag, S.S.
A single point mutation resulting in an adversely reduced expression of DPM2 in the Lec15.1 cells
Biochem. Biophys. Res. Commun.
312
555-561
2003
Cricetulus griseus
Arroyo-Flores, B.L.; Calvo-Mendez, C.; Flores-Carreon, A.; Lopez-Romero, E.
Biosynthesis of glycoproteins in the pathogenic fungus Candida albicans: activation of dolichol phosphate mannose synthase by cAMP-mediated protein phosphorylation
FEMS Immunol. Med. Microbiol.
45
429-434
2005
Candida albicans
Banerjee, D.K.; Aponte, E.; Dasilva, J.J.
Low expression of lipid-linked oligosaccharide due to a functionally altered Dol-P-Man synthase reduces protein glycosylation in cAMP-dependent protein kinase deficient Chinese hamster ovary cells
Glycoconj. J.
21
479-486
2004
Cricetulus griseus
Banerjee, D.K.; Carrasquillo, E.A.; Hughey, P.; Schutzbach, J.S.; Martinez, J.A.; Baksi, K.
In vitro phosphorylation by cAMP-dependent protein kinase up-regulates recombinant Saccharomyces cerevisiae mannosylphosphodolichol synthase
J. Biol. Chem.
280
4174-4181
2005
Saccharomyces cerevisiae (P14020), Saccharomyces cerevisiae
Orlowski, J.; Machula, K.; Janik, A.; Zdebska, E.; Palamarczyk, G.
Dissecting the role of dolichol in cell wall assembly in the yeast mutants impaired in early glycosylation reactions
Yeast
24
239-252
2007
Saccharomyces cerevisiae
Flores-Carreon, A.; Lopez-Romero, E.
Biosynthesis of glycoproteins in the human pathogenic fungus Sporothrix schenckii: synthesis of dolichol phosphate mannose and mannoproteins by membrane-bound and solubilized mannosyl transferases
Antonie van Leeuwenhoek
88
221-230
2005
Sporothrix schenckii
Perlinska-Lenart, U.; Orlowski, J.; Laudy, A.E.; Zdebska, E.; Palamarczyk, G.; Kruszewska, J.S.
Glycoprotein hypersecretion alters the cell wall in Trichoderma reesei strains expressing the Saccharomyces cerevisiae dolichylphosphate mannose synthase gene
Appl. Environ. Microbiol.
72
7778-7784
2006
Saccharomyces cerevisiae
Salgado, M.; Villagomez-Castro, J.C.; Rocha-Rodriguez, R.; Sabanero-Lopez, M.; Ramos, M.A.; Alagon, A.; Lopez-Romero, E.; Sanchez-Lopez, R.
Entamoeba histolytica: biochemical and molecular insights into the activities within microsomal fractions
Exp. Parasitol.
110
363-373
2005
Entamoeba histolytica
Lamani, E.; Mewbourne, R.B.; Fletcher, D.S.; Maltsev, S.D.; Danilov, L.L.; Veselovsky, V.V.; Lozanova, A.V.; Grigorieva, N.Y.; Pinsker, O.A.; Xing, J.; Forsee, W.T.; Cheung, H.C.; Schutzbach, J.S.; Shibaev, V.N.; Jedrzejas, M.J.
Structural studies and mechanism of Saccharomyces cerevisiae dolichyl-phosphate-mannose synthase: insights into the initial step of synthesis of dolichyl-phosphate-linked oligosaccharide chains in membranes of endoplasmic reticulum
Glycobiology
16
666-678
2006
Saccharomyces cerevisiae
Ashida, H.; Maeda, Y.; Kinoshita, T.
DPM1, the catalytic subunit of dolichol-phosphate mannose synthase, is tethered to and stabilized on the endoplasmic reticulum membrane by DPM3
J. Biol. Chem.
281
896-904
2006
Cricetulus griseus
Shams-Eldin, H.; de Macedo, C.S.; Niehus, S.; Dorn, C.; Kimmel, J.; Azzouz, N.; Schwarz, R.T.
Plasmodium falciparum dolichol phosphate mannose synthase represents a novel clade
Biochem. Biophys. Res. Commun.
370
388-393
2008
Plasmodium falciparum
Baksi, K.; Tavarez-Pagan, J.J.; Martinez, J.A.; Banerjee, D.K.
Unique structural motif supports mannosylphospho dolichol synthase: an important angiogenesis regulator
Curr. Drug Targets
9
262-271
2008
Bos taurus
Urushibata, Y.; Ebisu, S.; Matsui, I.
A thermostable dolichol phosphoryl mannose synthase responsible for glycoconjugate synthesis of the hyperthermophilic archaeon Pyrococcus horikoshii
Extremophiles
12
665-676
2008
Pyrococcus horikoshii
Zhang, Z.; Banerjee, A.; Baksi, K.; Banerjee, D.
Mannosylphosphodolichol synthase overexpression supports angiogenesis
Biocatal. Biotransform.
28
90-98
2010
synthetic construct
Smith, T.K.; Young, B.L.; Denton, H.; Hughes, D.L.; Wagner, G.K.
First small molecular inhibitors of T. brucei dolicholphosphate mannose synthase (DPMS), a validated drug target in African sleeping sickness
Bioorg. Med. Chem. Lett.
19
1749-1752
2009
Trypanosoma brucei
Baksi, K.; Zhang, Z.; Banerjee, A.; Banerjee, D.K.
Cloning and expression of mannosylphospho dolichol synthase from bovine adrenal medullary capillary endothelial cells
Glycoconj. J.
26
635-645
2009
Bos taurus
Yamamoto, A.; Nakatsu, S.; Kondo, A.; Asato, T.; Okabe, M.; Fukuzawa, M.; Miyagawa, S.
A newly cloned pig dolichyl-phosphate mannosyl-transferase for preventing the transmission of porcine endogenous retrovirus to human cells
Transpl. Int.
23
424-431
2010
Sus scrofa
Calo, D.; Guan, Z.; Eichler, J.
Glyco-engineering in Archaea: differential N-glycosylation of the S-layer glycoprotein in a transformed Haloferax volcanii strain
Microb. Biotechnol.
4
461-470
2011
Haloferax volcanii, Haloferax volcanii WR536 (H53)
Zembek, P.; Perlinska-Lenart, U.; Brunner, K.; Reithner, B.; Palamarczyk, G.; Mach, R.L.; Kruszewska, J.S.
Elevated activity of dolichyl phosphate mannose synthase enhances biocontrol abilities of Trichoderma atroviride
Mol. Plant Microbe Interact.
24
1522-1529
2011
Saccharomyces cerevisiae
Jadid, N.; Mialoundama, A.S.; Heintz, D.; Ayoub, D.; Erhardt, M.; Mutterer, J.; Meyer, D.; Alioua, A.; Van Dorsselaer, A.; Rahier, A.; Camara, B.; Bouvier, F.
Dolichol phosphate mannose synthase1 mediates the biogenesis of isoprenyl-linked glycans and influences development, stress response, and ammonium hypersensitivity in Arabidopsis
Plant Cell
23
1985-2005
2011
Arabidopsis thaliana
Marchese, M.; Pappalardo, A.; Baldacci, J.; Verri, T.; Doccini, S.; Cassandrini, D.; Bruno, C.; Fiorillo, C.; Garcia-Gil, M.; Bertini, E.; Pitto, L.; Santorelli, F.M.
Dolichol-phosphate mannose synthase depletion in zebrafish leads to dystrophic muscle with hypoglycosylated alpha-dystroglycan
Biochem. Biophys. Res. Commun.
477
137-143
2016
Danio rerio (Q6DEJ9 and Q561S6 and Q1LXA2)
Labeau, A.; Simon-Loriere, E.; Hafirassou, M.L.; Bonnet-Madin, L.; Tessier, S.; Zamborlini, A.; Dupre, T.; Seta, N.; Schwartz, O.; Chaix, M.; Delaugerre, C.; Amara, A.; Meertens, L.
A genome-wide CRISPR-Cas9 screen identifies the dolichol-phosphate mannose synthase complex as a host dependency factor for dengue virus infection
J. Virol.
94
e01751
2020
Homo sapiens (O60762 and Q9P2X0)
Gandini, R.; Reichenbach, T.; Tan, T.; Divne, C.
Structural basis for dolichylphosphate mannose biosynthesis
Nat. Commun.
8
120
2017
Pyrococcus furiosus (Q8U4M3), Pyrococcus furiosus, Pyrococcus furiosus ATCC 43587 (Q8U4M3), Pyrococcus furiosus Vc1 (Q8U4M3), Pyrococcus furiosus JCM 8422 (Q8U4M3)
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