Disease on EC 2.4.1.144 - beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase
Please use the Disease Search for a specific query.
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Abortion, Spontaneous
Altered ?1,6-GlcNAc and bisecting GlcNAc-branched N-glycan on integrin ?1 are associated with early spontaneous miscarriage in humans.
Alzheimer Disease
GLP-1 receptor agonists downregulate aberrant GnT-III expression in Alzheimer's disease models through the Akt/GSK-3?/?-catenin signaling.
Alzheimer Disease
MicroRNA-23b attenuates tau pathology and inhibits oxidative stress by targeting GnT-III in Alzheimer's disease.
beta-1,4-mannosyl-glycoprotein 4-beta-n-acetylglucosaminyltransferase deficiency
Bisecting GlcNAc modification stabilizes BACE1 protein under oxidative stress conditions.
Blast Crisis
Changes of beta-1,4-N-acetylglucosaminyltransferase III (GnT-III) in patients with leukaemia.
Blast Crisis
High expression of UDP-N-acetylglucosamine: beta-D mannoside beta-1,4-N-acetylglucosaminyltransferase III (GnT-III) in chronic myelogenous leukemia in blast crisis.
Breast Neoplasms
Expression of N-Acetylglucosaminyltransferase III Suppresses ?2,3-Sialylation, and Its Distinctive Functions in Cell Migration Are Attributed to ?2,6-Sialylation Levels.
Carcinogenesis
?4-integrin/PI3K Signaling Promotes Tumor Progression through Galectin-3-N-glycan Complex.
Carcinogenesis
Expression of N-acetylglucosaminyltransferase III in hepatic nodules during rat liver carcinogenesis promoted by orotic acid.
Carcinogenesis
Expression of N-acetylglucosaminyltransferase III in hepatic nodules generated by different models of rat liver carcinogenesis.
Carcinoma
Alteration in N -acetylglucosaminyltransferase activities and glycan structure in tissue and bile glycoproteins from extrahepatic bile duct carcinoma.
Carcinoma
N-acetylglucosaminyltransferase III expression is regulated by cell-cell adhesion via the E-cadherin-catenin-actin complex.
Carcinoma
The glycosyltransferase GnT-III activates Notch signaling and drives stem cell expansion to promote the growth and invasion of ovarian cancer.
Carcinoma, Ductal
N-Acetylglucosaminyltransferase III (GnT-III) but not N-Acetylgalactosaminyltransferase-6 and 8 are Differentially Expressed in Invasive and In Situ Ductal Carcinoma of the Breast.
Carcinoma, Hepatocellular
Bisecting GlcNAc structures act as negative sorting signals for cell surface glycoproteins in forskolin-treated rat hepatoma cells.
Carcinoma, Hepatocellular
Caveolin-1 regulates the functional localization of N-acetylglucosaminyltransferase III within the golgi apparatus.
Carcinoma, Hepatocellular
Determination of N-acetylglucosaminyltransferases III, IV and V in normal and hepatoma tissues of rats.
Carcinoma, Hepatocellular
Determination of UDP-N-acetylglucosamine: beta-D-mannoside-1,4-N-acetylglucosaminyltransferase-III in patients sera with chronic hepatitis and liver cirrhosis using a monoclonal antibody.
Carcinoma, Hepatocellular
Elevated expression of bisecting N-acetylglucosaminyltransferase-III gene in a human fetal hepatocyte cell line by hepatitis B virus.
Carcinoma, Hepatocellular
Expression of bisecting N-acetylglucosaminyltransferase-III in human hepatocarcinoma tissues, fetal liver tissues, and hepatoma cell lines of Hep3B and HepG2.
Carcinoma, Hepatocellular
Expression of N-acetylglucosaminyltransferase III in hepatic nodules during rat liver carcinogenesis promoted by orotic acid.
Carcinoma, Hepatocellular
Expression of N-Acetylglucosaminyltransferase III Suppresses ?2,3-Sialylation, and Its Distinctive Functions in Cell Migration Are Attributed to ?2,6-Sialylation Levels.
Carcinoma, Hepatocellular
High expression of an N-acetylglucosaminyltransferase III in 3'-methyl DAB-induced hepatoma and ascites hepatoma.
Carcinoma, Hepatocellular
N-acetylglucosaminyltransferase III and V messenger RNA levels in LEC rats during hepatocarcinogenesis.
Carcinoma, Hepatocellular
N-acetylglucosaminyltransferase III in human serum, and liver and hepatoma tissues: increased activity in liver cirrhosis and hepatoma patients.
Carcinoma, Hepatocellular
Reduced N-acetylglucosaminyltransferase III expression via Smad3 and Erk signaling in TGF-?1-induced HCC EMT model.
Carcinoma, Hepatocellular
Serum N-acetylglucosaminyltransferase III activities in hepatocellular carcinoma.
Carcinoma, Hepatocellular
Transfection of N-acetylglucosaminyltransferase III gene suppresses expression of hepatitis B virus in a human hepatoma cell line, HB611.
Carcinoma, Intraductal, Noninfiltrating
N-Acetylglucosaminyltransferase III (GnT-III) but not N-Acetylgalactosaminyltransferase-6 and 8 are Differentially Expressed in Invasive and In Situ Ductal Carcinoma of the Breast.
Carcinoma, Ovarian Epithelial
The glycosyltransferase GnT-III activates Notch signaling and drives stem cell expansion to promote the growth and invasion of ovarian cancer.
Carcinoma, Renal Cell
Changes in N-acetylglucosaminyltransferase III, IV and V in renal cell carcinoma.
Choriocarcinoma
Unusually high expression of N-acetylglucosaminyltransferase-IVa in human choriocarcinoma cell lines: a possible enzymatic basis of the formation of abnormal biantennary sugar chain.
Colitis
Modulation of N-glycosylation by mesalamine facilitates membranous E-cadherin expression in colon epithelial cells.
Colonic Neoplasms
Cell cycle-dependent regulation of N-acetylglucosaminyltransferase-III in a human colon cancer cell line, Colo201.
Glioma
Expression of N-Acetylglucosaminyltransferase III Suppresses ?2,3-Sialylation, and Its Distinctive Functions in Cell Migration Are Attributed to ?2,6-Sialylation Levels.
Hematologic Diseases
High expression of UDP-N-acetylglucosamine: beta-D mannoside beta-1,4-N-acetylglucosaminyltransferase III (GnT-III) in chronic myelogenous leukemia in blast crisis.
Hematologic Neoplasms
High expression of UDP-N-acetylglucosamine: beta-D mannoside beta-1,4-N-acetylglucosaminyltransferase III (GnT-III) in chronic myelogenous leukemia in blast crisis.
Hepatitis B
Elevated expression of bisecting N-acetylglucosaminyltransferase-III gene in a human fetal hepatocyte cell line by hepatitis B virus.
Hepatitis B
Remodeling of cell surface glycoproteins by N-acetylglucosaminyltransferase III gene transfection: modulation of metastatic potentials and down regulation of hepatitis B virus replication.
Hepatitis B
Selective suppression of N-acetylglucosaminyltransferase III activity in a human hepatoblastoma cell line transfected with hepatitis B virus.
Hepatitis B
The hepatitis B virus X protein inhibits secretion of apolipoprotein B by enhancing the expression of N-acetylglucosaminyltransferase III.
Hepatitis B
Transfection of N-acetylglucosaminyltransferase III gene suppresses expression of hepatitis B virus in a human hepatoma cell line, HB611.
Hepatitis, Chronic
N-acetylglucosaminyltransferase III and V messenger RNA levels in LEC rats during hepatocarcinogenesis.
Hepatitis, Chronic
Serum N-acetylglucosaminyltransferase III activities in hepatocellular carcinoma.
Hepatoblastoma
Selective suppression of N-acetylglucosaminyltransferase III activity in a human hepatoblastoma cell line transfected with hepatitis B virus.
Infections
Elevated expression of bisecting N-acetylglucosaminyltransferase-III gene in a human fetal hepatocyte cell line by hepatitis B virus.
Infections
Sensitivity to human serum of gammaretroviruses produced from pig endothelial cells transduced with glycosyltransferase genes.
Infections
Serum N-acetylglucosaminyltransferase III activities in hepatocellular carcinoma.
Leukemia
Sensitivity to human serum of gammaretroviruses produced from pig endothelial cells transduced with glycosyltransferase genes.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
High expression of UDP-N-acetylglucosamine: beta-D mannoside beta-1,4-N-acetylglucosaminyltransferase III (GnT-III) in chronic myelogenous leukemia in blast crisis.
Liver Cirrhosis
Elevated expression of bisecting N-acetylglucosaminyltransferase-III gene in a human fetal hepatocyte cell line by hepatitis B virus.
Liver Cirrhosis
N-acetylglucosaminyltransferase III in human serum, and liver and hepatoma tissues: increased activity in liver cirrhosis and hepatoma patients.
Liver Cirrhosis
Serum N-acetylglucosaminyltransferase III activities in hepatocellular carcinoma.
Lymphatic Metastasis
N-acetylglucosaminyltransferase III and V messenger RNA levels in LEC rats during hepatocarcinogenesis.
Lymphoma
N-acetylglucosaminyltransferase III, IV and V activities in Novikoff ascites tumour cells, mouse lymphoma cells and hen oviduct. Application of a sensitive and specific assay by use of high-performance liquid chromatography.
Melanoma
Aberrant glycosylation of E-cadherin enhances cell-cell binding to suppress metastasis.
Melanoma
Implication of N-acetylglucosaminyltransferases III and V in cancer: gene regulation and signaling mechanism.
Melanoma
Introduction of bisecting GlcNAc in N-glycans of adenylyl cyclase III enhances its activity.
Melanoma
Overexpression of N-acetylglucosaminyltransferases III and V in human melanoma cells. Implications for MCAM N-glycosylation.
Melanoma
Remodeling of glycoconjugates on CD44 enhances cell adhesion to hyaluronate, tumor growth and metastasis in B16 melanoma cells expressing beta1,4-N-acetylglucosaminyltransferase III.
Melanoma
Suppression of lung metastasis of B16 mouse melanoma by N-acetylglucosaminyltransferase III gene transfection.
Melanoma
The glycomic effect of N-acetylglucosaminyltransferase III overexpression in metastatic melanoma cells. GnT-III modifies highly branched N-glycans.
Melanoma
[Suppression of lung metastasis of B16 mouse melanoma cells by introduction of N-acetylglucosaminyltransferase III gene]
Melanoma, Experimental
Introduction of bisecting GlcNAc into integrin alpha5beta1 reduces ligand binding and down-regulates cell adhesion and cell migration.
Melanoma, Experimental
Remodeling of glycoconjugates on CD44 enhances cell adhesion to hyaluronate, tumor growth and metastasis in B16 melanoma cells expressing beta1,4-N-acetylglucosaminyltransferase III.
Multiple Myeloma
Changes of beta-1,4-N-acetylglucosaminyltransferase III (GnT-III) in patients with leukaemia.
Multiple Myeloma
High expression of UDP-N-acetylglucosamine: beta-D mannoside beta-1,4-N-acetylglucosaminyltransferase III (GnT-III) in chronic myelogenous leukemia in blast crisis.
Neoplasm Metastasis
Aberrant glycosylation of E-cadherin enhances cell-cell binding to suppress metastasis.
Neoplasm Metastasis
Altered ?1,6-GlcNAc and bisecting GlcNAc-branched N-glycan on integrin ?1 are associated with early spontaneous miscarriage in humans.
Neoplasm Metastasis
Downregulated N-acetylglucosaminyltransferase III is involved in attenuating trophoblast migration and invasion under hypoxia-reoxygenation condition.
Neoplasm Metastasis
Expression of N-Acetylglucosaminyltransferase III Promotes Trophoblast Invasion and Migration in Early Human Placenta.
Neoplasm Metastasis
Expression of N-Acetylglucosaminyltransferase III Suppresses ?2,3-Sialylation, and Its Distinctive Functions in Cell Migration Are Attributed to ?2,6-Sialylation Levels.
Neoplasm Metastasis
Glycans and cancer: role of N-glycans in cancer biomarker, progression and metastasis, and therapeutics.
Neoplasm Metastasis
Implication of N-acetylglucosaminyltransferases III and V in cancer: gene regulation and signaling mechanism.
Neoplasm Metastasis
Loss and recovery of Mgat3 and GnT-III Mediated E-cadherin N-glycosylation is a mechanism involved in epithelial-mesenchymal-epithelial transitions.
Neoplasm Metastasis
N-acetylglucosaminyltransferase III and V messenger RNA levels in LEC rats during hepatocarcinogenesis.
Neoplasm Metastasis
N-acetylglucosaminyltransferase III antagonizes the effect of N-acetylglucosaminyltransferase V on alpha3beta1 integrin-mediated cell migration.
Neoplasm Metastasis
Potential of N-glycan in cell adhesion and migration as either a positive or negative regulator.
Neoplasm Metastasis
Remodeling of glycoconjugates on CD44 enhances cell adhesion to hyaluronate, tumor growth and metastasis in B16 melanoma cells expressing beta1,4-N-acetylglucosaminyltransferase III.
Neoplasm Metastasis
Roles of N-acetylglucosaminyltransferase III in epithelial-to-mesenchymal transition induced by transforming growth factor ?1 (TGF-?1) in epithelial cell lines.
Neoplasm Metastasis
Suppression of lung metastasis of B16 mouse melanoma by N-acetylglucosaminyltransferase III gene transfection.
Neoplasm Metastasis
TGF-?1 Causes EMT by regulating N-Acetyl Glucosaminyl Transferases via Downregulation of Non Muscle Myosin II-A through JNK/P38/PI3K pathway in lung cancer.
Neoplasm Metastasis
The Role of N-acetylglucosaminyltransferase III and V in the Post-Transcriptional Modifications of E-cadherin.
Neoplasm Metastasis
[Suppression of lung metastasis of B16 mouse melanoma cells by introduction of N-acetylglucosaminyltransferase III gene]
Neoplasms
?4-integrin/PI3K Signaling Promotes Tumor Progression through Galectin-3-N-glycan Complex.
Neoplasms
A glycomic approach to hepatic tumors in N-acetylglucosaminyltransferase III (GnT-III) transgenic mice induced by diethylnitrosamine (DEN): identification of haptoglobin as a target molecule of GnT-III.
Neoplasms
All-trans-retinoic acid modulates ICAM-1 N-glycan composition by influencing GnT-III levels and inhibits cell adhesion and trans-endothelial migration.
Neoplasms
Alteration in N -acetylglucosaminyltransferase activities and glycan structure in tissue and bile glycoproteins from extrahepatic bile duct carcinoma.
Neoplasms
Altered glycosylation of proteins produced by malignant cells, and application for the diagnosis and immunotherapy of tumours.
Neoplasms
Changes of beta-1,4-N-acetylglucosaminyltransferase III (GnT-III) in patients with leukaemia.
Neoplasms
Downregulated N-acetylglucosaminyltransferase III is involved in attenuating trophoblast migration and invasion under hypoxia-reoxygenation condition.
Neoplasms
E-cadherin and adherens-junctions stability in gastric carcinoma: Functional implications of glycosyltransferases involving N-glycan branching biosynthesis, N-acetylglucosaminyltransferases III and V.
Neoplasms
Expression of N-Acetylglucosaminyltransferase III Promotes Trophoblast Invasion and Migration in Early Human Placenta.
Neoplasms
Expression of N-Acetylglucosaminyltransferase III Suppresses ?2,3-Sialylation, and Its Distinctive Functions in Cell Migration Are Attributed to ?2,6-Sialylation Levels.
Neoplasms
Glycans and cancer: role of N-glycans in cancer biomarker, progression and metastasis, and therapeutics.
Neoplasms
Implication of N-acetylglucosaminyltransferases III and V in cancer: gene regulation and signaling mechanism.
Neoplasms
Modulation of N-glycosylation by mesalamine facilitates membranous E-cadherin expression in colon epithelial cells.
Neoplasms
N-Acetylglucosaminyltransferase III (GnT-III) but not N-Acetylgalactosaminyltransferase-6 and 8 are Differentially Expressed in Invasive and In Situ Ductal Carcinoma of the Breast.
Neoplasms
N-acetylglucosaminyltransferase III and V messenger RNA levels in LEC rats during hepatocarcinogenesis.
Neoplasms
N-acetylglucosaminyltransferase III, IV and V activities in Novikoff ascites tumour cells, mouse lymphoma cells and hen oviduct. Application of a sensitive and specific assay by use of high-performance liquid chromatography.
Neoplasms
New evidence for an extra-hepatic role of N-acetylglucosaminyltransferase III in the progression of diethylnitrosamine-induced liver tumors in mice.
Neoplasms
Potential of N-glycan in cell adhesion and migration as either a positive or negative regulator.
Neoplasms
Reduced hepatocyte proliferation is the basis of retarded liver tumor progression and liver regeneration in mice lacking N-acetylglucosaminyltransferase III.
Neoplasms
Reduced N-acetylglucosaminyltransferase III expression via Smad3 and Erk signaling in TGF-?1-induced HCC EMT model.
Neoplasms
Remodeling of glycoconjugates on CD44 enhances cell adhesion to hyaluronate, tumor growth and metastasis in B16 melanoma cells expressing beta1,4-N-acetylglucosaminyltransferase III.
Neoplasms
Roles of N-acetylglucosaminyltransferase III in epithelial-to-mesenchymal transition induced by transforming growth factor ?1 (TGF-?1) in epithelial cell lines.
Neoplasms
The glycomic effect of N-acetylglucosaminyltransferase III overexpression in metastatic melanoma cells. GnT-III modifies highly branched N-glycans.
Neoplasms
The glycosyltransferase GnT-III activates Notch signaling and drives stem cell expansion to promote the growth and invasion of ovarian cancer.
Neoplasms
Transfection of 2,6 and 2,3-sialyltransferase genes and GlcNAc-transferase genes into human glioma cell line U-373 MG affects glycoconjugate expression and enhances cell death.
Neoplasms
True significance of N-acetylglucosaminyltransferases GnT-III, V and ?1,6 fucosyltransferase in epithelial-mesenchymal transition and cancer.
Neuroblastoma
Introduction of bisecting GlcNAc in N-glycans of adenylyl cyclase III enhances its activity.
Neuroblastoma
N-acetylglucosaminyltransferase III antagonizes the effect of N-acetylglucosaminyltransferase V on alpha3beta1 integrin-mediated cell migration.
Neuroblastoma
Protective effect of N-glycan bisecting GlcNAc residues on {beta}-amyloid production in Alzheimer's disease.
Obesity
Hyperexpression of N-acetylglucosaminyltransferase-III in liver tissues of transgenic mice causes fatty body and obesity through severe accumulation of Apo A-I and Apo B.
Ovarian Neoplasms
Expression of N-Acetylglucosaminyltransferase III Suppresses ?2,3-Sialylation, and Its Distinctive Functions in Cell Migration Are Attributed to ?2,6-Sialylation Levels.
Ovarian Neoplasms
Glycomic analysis of membrane glycoproteins with bisecting glycosylation from ovarian cancer tissues reveals novel structures and functions.
Ovarian Neoplasms
The glycosyltransferase GnT-III activates Notch signaling and drives stem cell expansion to promote the growth and invasion of ovarian cancer.
Pheochromocytoma
Beta1,4-N-Acetylglucosaminyltransferase III down-regulates neurite outgrowth induced by costimulation of epidermal growth factor and integrins through the Ras/ERK signaling pathway in PC12 cells.
Pheochromocytoma
Overexpression of N-acetylglucosaminyltransferase III disrupts the tyrosine phosphorylation of Trk with resultant signaling dysfunction in PC12 cells treated with nerve growth factor.
Pre-Eclampsia
Downregulated N-acetylglucosaminyltransferase III is involved in attenuating trophoblast migration and invasion under hypoxia-reoxygenation condition.
Prion Diseases
Glycosylation differences between the normal and pathogenic prion protein isoforms.
Starvation
beta1,4-N-Acetylglucosaminyltransferase III potentiates beta1 integrin-mediated neuritogenesis induced by serum deprivation in Neuro2a cells.
Stomach Neoplasms
E-cadherin and adherens-junctions stability in gastric carcinoma: Functional implications of glycosyltransferases involving N-glycan branching biosynthesis, N-acetylglucosaminyltransferases III and V.
Stomach Neoplasms
Expression of N-Acetylglucosaminyltransferase III Suppresses ?2,3-Sialylation, and Its Distinctive Functions in Cell Migration Are Attributed to ?2,6-Sialylation Levels.
html completed