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Reference on EC 2.3.3.8 - ATP citrate synthase

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Spector, L.B.
Citrate cleavage and related enzymes
The Enzymes, 3rd Ed. (Boyer, P. D. , ed. )
7
357-389
1972
Bos taurus, Gallus gallus, Columba livia, Oryctolagus cuniculus, Rattus norvegicus, Sus scrofa
-
Manually annotated by BRENDA team
Evans, C.T.; Ratledge, C.
Possible regulatory roles of ATP:citrate lyase, malic enzyme, and AMP deaminase in lipid accumulation by Rhodsporidium toruloides CBS 14
Can. J. Microbiol.
31
1000-1005
1985
Rhodotorula toruloides, Rhodotorula toruloides CBS 13
-
Manually annotated by BRENDA team
Houston, B.; Nimmo, H.G.
Effects of phosphorylation on the kinetic properties of rat liver ATP-citrate lyase
Biochim. Biophys. Acta
844
233-239
1985
Rattus norvegicus
Manually annotated by BRENDA team
Wraight, C.; Day, A.; Hoogenraad, N.; Scopes, R.
A two-step purification of ATP-citrate lyase from rat liver and its use in a fluorometric assay for N-acetylglutamate synthetase
Anal. Biochem.
144
604-609
1985
Rattus norvegicus
Manually annotated by BRENDA team
Houston, B.; Nimmo, H.G.
Purification and some kinetic properties of rat liver ATP citrate lyase
Biochem. J.
224
437-443
1984
Rattus norvegicus
Manually annotated by BRENDA team
Boulton, C.A.; Ratledge, C.
Partial purification and some properties of ATP:citrate lyase from the oleaginous yeast Lipomyces starkeyi
J. Gen. Microbiol.
129
2863-2869
1983
Lipomyces starkeyi, Lipomyces starkeyi CBS 1809
-
Manually annotated by BRENDA team
Szutowicz, A.; Srere, P.A.
Purification and some properties of ATP-citrate lyase from rat brain
Arch. Biochem. Biophys.
221
168-174
1983
Rattus norvegicus
Manually annotated by BRENDA team
Antranikian, G.; Herzberg, C.; Gottschalk, G.
Characterization of ATP citrate lyase from Chlorobium limicola
J. Bacteriol.
152
1284-1287
1982
Chlorobium limicola
Manually annotated by BRENDA team
Redshaw, J.C.; Loten, E.G.
A rapid purification of hepatic ATP citrate lyase using blue Sepharose
FEBS Lett.
123
261-264
1981
Rattus norvegicus
Manually annotated by BRENDA team
Guy, P.S.; Cohen, P.; Hardie, D.G.
Purification and physicochemical properties of ATP citrate (pro-3S) lyase from lactating rat mammary gland and studies of its reversible phosphorylation
Eur. J. Biochem.
114
399-405
1981
Rattus norvegicus
Manually annotated by BRENDA team
Hoffmann, G.E.; Andres, H.; Weiss, L.; Kreisel, C.; Sander, R.
Properties and organ distribution of ATP citrate (pro-3S)-lyase
Biochim. Biophys. Acta
620
151-158
1980
Gallus gallus, Homo sapiens, Rattus norvegicus
Manually annotated by BRENDA team
Hoffmann, G.E.; Kraupe, P.; Weiss, L.; Wittmann, J.
Avian ATP citrate (pro-3S)-lyase
Hoppe-Seyler's Z. Physiol. Chem.
361
1117-1119
1980
Gallus gallus, Columba livia, Rattus norvegicus
Manually annotated by BRENDA team
Ivanovsky, R.N.; Sintsov, N.V.; Kondratieva, E.N.
ATP-linked citrate lyase activity in the green sulfur bacterium Chlorobium limicola forma thiosulfatophilum
Arch. Microbiol.
128
239-241
1980
Chlorobium limicola
-
Manually annotated by BRENDA team
Ranganathan, N.S.; Srere, P.A.; Linn, T.C.
Comparison of phospho- and dephospho-ATP citrate lyase
Arch. Biochem. Biophys.
204
52-58
1980
Rattus norvegicus
Manually annotated by BRENDA team
Janski, A.M.; Cornell, N.W.
Association of ATP citrate lyase with mitochondria
Biochem. Biophys. Res. Commun.
92
305-312
1980
Rattus norvegicus
Manually annotated by BRENDA team
Hoffmann, G.E.; Schiessl, J.; Weiss, L.
ATP citrate (pro-3S)-lyase in the rat; two-step purification procedure, properties, organ distribution
Hoppe-Seyler's Z. Physiol. Chem.
360
1445-1451
1979
Rattus norvegicus
Manually annotated by BRENDA team
Fritsch, H.; Beevers, H.
ATP citrate lyase from germinating castor bean endosperm
Plant Physiol.
63
687-691
1979
Ricinus communis
Manually annotated by BRENDA team
Linn, T.; Srere, P.A.
Identification of ATP citrate lyase as a phosphoprotein
J. Biol. Chem.
254
1691-1698
1979
Rattus norvegicus
Manually annotated by BRENDA team
Singh, M.; Richards, E.G.; Mukherjee, A.; Srere, P.A.
Structure of ATP citrate lyase from rat liver. Physicochemical studies and proteolytic modification
J. Biol. Chem.
251
5242-5250
1976
Rattus norvegicus
Manually annotated by BRENDA team
Osterlund, B.; Bridger, W.A.
Effect of a peptide stabilizing factor on liver ATP citrate lyase
Biochem. Biophys. Res. Commun.
76
1-8
1977
Rattus norvegicus
Manually annotated by BRENDA team
Mahlen, A.
Purification and some properties of ATP citrate lyase from Penicillium spiculisporum
Eur. J. Biochem.
36
342-346
1973
Talaromyces trachyspermus
Manually annotated by BRENDA team
Lenz, H.; Buckel, W.; Wunderwald, P.; Biedermann, G.; Buschmeier, V.; Eggerer, H.; Cornforth, J.W.; Redmond, J.W.; Mallaby, R.
Stereochemistry of si-citrate synthase and ATP-citrate-lyase reactions
Eur. J. Biochem.
24
207-215
1971
Gallus gallus
Manually annotated by BRENDA team
Pentyala, S.N.; Benjamin, W.B.
Effect of oxaloacetate and phosphorylation on ATP-citrate lyase activity
Biochemistry
34
10961-10969
1995
Rattus norvegicus
Manually annotated by BRENDA team
Rider, C.C.; Wilson, A.P.
Inhibition of liver ATP citrate lyase in the presence of L-glutamate
Biochem. Soc. Trans.
13
152-153
1985
Rattus norvegicus
-
Manually annotated by BRENDA team
Choi, J.W.; Kim, K.S.; Park, S.W.; Whang, S.K.; Kim, Y.S.
Purification of ATP-citrate lyase in rat liver and molecular cloning of its cDNA
Korean J. Biochem.
23
223-230
1991
Rattus norvegicus
-
Manually annotated by BRENDA team
Dolle, R.E.; McNair, D.; Hughes, M.J.; Kruse, J.I.; Eggelston, D.; Saxty, B.A.; Wells, T.N.C.; Groot, P.H.E.
ATP-citrate lyase as a target for hypolipidemic intervention. Sulfoximine and 3-hydroxy-beta-lactam containing analogues of citric acid as potential tight-binding inhibitors
J. Med. Chem.
35
4875-4884
1992
Rattus norvegicus
Manually annotated by BRENDA team
Wahlund, T.M.; Tabita, F.R.
The reductive tricarboxylic acid cycle of carbon dioxide assimilation: initial studies and purification of ATP-citrate lyase from the green sulfur bacterium Chlorobium tepidum
J. Bacteriol.
179
4859-4867
1997
Chlorobaculum tepidum
Manually annotated by BRENDA team
Krivanek, J.; Novakova, L.
ATP-citrate lyase is another enzyme the histidine phosphorylation of which is inhibited by vanadate
FEBS Lett.
282
32-34
1991
Rattus norvegicus
Manually annotated by BRENDA team
Ishii, M.; Igarashi, Y.; Kodama, T.
Purification and characterization of ATP:citrate lyase from Hydrogenobacter thermophilus TK-6
J. Bacteriol.
171
1788-1792
1989
Hydrogenobacter thermophilus, Hydrogenobacter thermophilus TK-6 / IAM 12695
Manually annotated by BRENDA team
Wells, T.N.C.; Saxty, B.A.
Redox control of catalysis in ATP-citrate lysate from rat liver
Eur. J. Biochem.
204
249-255
1992
Rattus norvegicus
Manually annotated by BRENDA team
Wells, T.N.C.
ATP-citrate lyase from rat liver. Characterisation of the citryl-enzyme complexes
Eur. J. Biochem.
199
163-168
1991
Rattus norvegicus
Manually annotated by BRENDA team
Wagner, P.D.; Vu, N.D.
Phosphorylation of ATP-citrate lyase by nucleoside diphosphate kinase
J. Biol. Chem.
270
21758-21764
1995
Rattus norvegicus
Manually annotated by BRENDA team
Yu, K.T.; Benjamin, W.B.; Ramakrishna, S.; Khalaf, N.; Czech, M.P.
An insulin-sensitive cytosolic protein kinase accounts for the regulation of ATP citrate-lyase phosphorylation
Biochem. J.
268
539-545
1990
Rattus norvegicus
Manually annotated by BRENDA team
Adams, I.P.; Dack, S.; Dickinson, F.M.; Midgley, M.; Ratledge, C.
ATP: citrate lyase from Aspergillus nidulans
Biochem. Soc. Trans.
25
S670
1997
Aspergillus nidulans, Aspergillus nidulans R21
Manually annotated by BRENDA team
Shashi, K.; Bachhawat, A.K.; Joseph, R.
ATP:citrate lyase of Rhodotorula gracilis: purification and properties
Biochim. Biophys. Acta
1033
23-30
1990
Rhodotorula toruloides
Manually annotated by BRENDA team
Adams, I.P.; Dack, S.; Dickinson, F.M.; Ratledge, C.
The distinctiveness of ATP:citrate lyase from Aspergillus nidulans
Biochim. Biophys. Acta
1597
36-41
2002
Aspergillus nidulans
Manually annotated by BRENDA team
Tosukhowong, P.; Borvonpadungkitti, S.; Prasongwatana, V.; Tungsanga, K.; Jutuporn, S.; Dissayabutr, T.; Reungjui, S.; Sriboonlue, P.
Urinary citrate excretion in patients with renal stone: roles of leucocyte ATP citrate lyase activity and potassium salts therapy
Clin. Chim. Acta
325
71-78
2002
Homo sapiens
Manually annotated by BRENDA team
Ki, S.W.; Ishigami, K.; Kitahara, T.; Kasahara, K.; Yoshida, M.; Horinouchi, S.
Radicicol binds and inhibits mammalian ATP citrate lyase
J. Biol. Chem.
275
39231-39236
2000
Homo sapiens, Rattus norvegicus
Manually annotated by BRENDA team
Potapova, I.A.; El-Maghrabi, M.R.; Doronin, S.V.; Benjamin, W.B.
Phosphorylation of recombinant human ATP:citrate lyase by cAMP-dependent protein kinase abolishes homotropic allosteric regulation of the enzyme by citrate and increases the enzyme activity. Allosteric activation of ATP:citrate lyase by phosphorylated sugars
Biochemistry
39
1169-1179
2000
Homo sapiens, Rattus norvegicus
Manually annotated by BRENDA team
Fatland, B.L.; Ke, J.; Anderson, M.D.; Mentzen, W.I.; Cui, L.W.; Allred, C.C.; Johnston, J.L.; Nikolau, B.J.; Wurtele, E.S.
Molecular characterization of a heteromeric ATP-citrate lyase that generates cytosolic acetyl-coenzyme A in Arabidopsis
Plant Physiol.
130
740-756
2002
Arabidopsis sp., Pisum sativum
Manually annotated by BRENDA team
Rangasamy, D.; Ratledge, C.
Genetic enhancement of fatty acid synthesis by targeting rat liver ATP:citrate lyase into plastids of tobacco
Plant Physiol.
122
1231-1238
2000
Rattus norvegicus
Manually annotated by BRENDA team
Rangasamy, D.; Ratledge, C.
Compartmentation of ATP:citrate lyase in plants
Plant Physiol.
122
1225-1230
2000
Brassica napus, Nicotiana tabacum, Pisum sativum, Spinacia oleracea
Manually annotated by BRENDA team
Kanao, T.; Fukui, T.; Atomi, H.; Imanaka, T.
Kinetic and biochemical analyses on the reaction mechanism of a bacterial ATP-citrate lyase
Eur. J. Biochem.
269
3409-3416
2002
Chlorobium limicola
Manually annotated by BRENDA team
Kanao, T.; Fukui, T.; Atomi, H.; Imanaka, T.
ATP-citrate lyase from the green sulfur bacterium Chlorobium limicola is a heteromeric enzyme composed of two distinct gene products
Eur. J. Biochem.
268
1670-1678
2001
Chlorobium limicola (Q9AQH6), Chlorobium limicola
Manually annotated by BRENDA team
Tosukhowong, P.; Tungsanga, K.; Phongudom, S.; Sriboonlue, P.
Effects of potassium-magnesium citrate supplementation on cytosolic ATP citrate lyase and mitochondrial aconitase activity in leukocytes: a window on renal citrate metabolism
Int. J. Urol.
12
140-144
2005
Homo sapiens
Manually annotated by BRENDA team
Michno, A.; Skibowska, A.; Raszeja-Specht, A.; Cwikowska, J.; Szutowicz, A.
The role of adenosine triphosphate citrate lyase in the metabolism of acetyl coenzyme a and function of blood platelets in diabetes mellitus
Metabolism
53
66-72
2004
Homo sapiens
Manually annotated by BRENDA team
Ma, Y.; Jakowitsch, J.; Maier, T.L.; Bayer, M.G.; Muller, N.E.; Schenk, H.E.; Loffelhardt, W.
ATP citrate lyase in the glaucocystophyte alga Cyanophora paradoxa is a cytosolic enzyme: characterisation of the gene for the large subunit at the cDNA and genomic levels
Mol. Genet. Genomics
266
231-238
2001
Cyanophora paradoxa (Q9XGL5), Cyanophora paradoxa
Manually annotated by BRENDA team
Fatland, B.L.; Nikolau, B.J.; Wurtele, E.S.
Reverse genetic characterization of cytosolic acetyl-CoA generation by ATP-citrate lyase in Arabidopsis
Plant Cell
17
182-203
2005
Arabidopsis thaliana
Manually annotated by BRENDA team
Li, J.J.; Wang, H.; Tino, J.A.; Robl, J.A.; Herpin, T.F.; Lawrence, R.M.; Biller, S.; Jamil, H.; Ponticiello, R.; Chen, L.; Chu, C.H.; Flynn, N.; Cheng, D.; Zhao, R.; Chen, B.; Schnur, D.; Obermeier, M.T.; Sasseville, V.; Padmanabha, R.; Pike, K.; Harrity, T.
2-Hydroxy-N-arylbenzenesulfonamides as ATP-citrate lyase inhibitors
Bioorg. Med. Chem. Lett.
17
3208-3211
2007
Homo sapiens, Mus musculus
Manually annotated by BRENDA team
Hatzivassiliou, G.; Zhao, F.; Bauer, D.E.; Andreadis, C.; Shaw, A.N.; Dhanak, D.; Hingorani, S.R.; Tuveson, D.A.; Thompson, C.B.
ATP citrate lyase inhibition can suppress tumor cell growth
Cancer Cell
8
311-321
2005
Homo sapiens, Mus musculus
Manually annotated by BRENDA team
Kim, W.; Tabita, F.R.
Both subunits of ATP-citrate lyase from Chlorobium tepidum contribute to catalytic activity
J. Bacteriol.
188
6544-6552
2006
Chlorobaculum tepidum
Manually annotated by BRENDA team
Bauer, D.E.; Hatzivassiliou, G.; Zhao, F.; Andreadis, C.; Thompson, C.B.
ATP citrate lyase is an important component of cell growth and transformation
Oncogene
24
6314-6322
2005
Mus musculus
Manually annotated by BRENDA team
MacDonald, M.J.; Hasan, N.M.; Longacre, M.J.
Studies with leucine, beta -hydroxybutyrate and ATP citrate lyase-deficient beta cells support the acetoacetate pathway of insulin secretion
Biochim. Biophys. Acta
1780
966-972
2008
Rattus norvegicus
Manually annotated by BRENDA team
Voordeckers, J.W.; Do, M.H.; Huegler, M.; Ko, V.; Sievert, S.M.; Vetriani, C.
Culture dependent and independent analyses of 16S rRNA and ATP citrate lyase genes: a comparison of microbial communities from different black smoker chimneys on the Mid-Atlantic Ridge
Extremophiles
12
627-640
2008
Chlorobium limicola, Persephonella marina, Sulfurihydrogenibium subterraneum, Nitratifractor salsuginis, Hydrogenimonas thermophila, Candidatus Arcobacter sulfidicus, Sulfurovum lithotrophicum, Sulfurimonas autotrophica, Sulfurimonas denitrificans, Lebetimonas acidiphila, Nautilia sp., Caminibacter hydrogeniphilus, Caminibacter sp., Caminibacter profundus, Caminibacter mediatlanticus, Desulfurobacterium thermolithotrophum, Desulfurobacterium crinifex, Thermovibrio ruber, Balnearium lithotrophicum, Thioreductor micantisoli, Caminibacter sp. TB-1
Manually annotated by BRENDA team
Chavez-Cabrera, C.; Flores-Bustamante, Z.R.; Marsch, R.; Montes, M.d.e.l..C.; Sanchez, S.; Cancino-Diaz, J.C.; Flores-Cotera, L.B.
ATP-citrate lyase activity and carotenoid production in batch cultures of Phaffia rhodozyma under nitrogen-limited and nonlimited conditions
Appl. Microbiol. Biotechnol.
85
1953-1960
2010
Phaffia rhodozyma, Phaffia rhodozyma NRRL Y-10922
Manually annotated by BRENDA team
Migita, T.; Narita, T.; Nomura, K.; Miyagi, E.; Inazuka, F.; Matsuura, M.; Ushijima, M.; Mashima, T.; Seimiya, H.; Satoh, Y.; Okumura, S.; Nakagawa, K.; Ishikawa, Y.
ATP citrate lyase: activation and therapeutic implications in non-small cell lung cancer
Cancer Res.
68
8547-8554
2008
Homo sapiens
Manually annotated by BRENDA team
Wang, Q.; Jiang, L.; Wang, J.; Li, S.; Yu, Y.; You, J.; Zeng, R.; Gao, X.; Rui, L.; Li, W.; Liu, Y.
Abrogation of hepatic ATP-citrate lyase protects against fatty liver and ameliorates hyperglycemia in leptin receptor-deficient mice
Hepatology
49
1166-1175
2009
Mus musculus
Manually annotated by BRENDA team
Beckner, M.E.; Fellows-Mayle, W.; Zhang, Z.; Agostino, N.R.; Kant, J.A.; Day, B.W.; Pollack, I.F.
Identification of ATP citrate lyase as a positive regulator of glycolytic function in glioblastomas
Int. J. Cancer
126
2282-2295
2009
Homo sapiens, Homo sapiens (P53396)
Manually annotated by BRENDA team
Meijer, S.; Nielsen, M.L.; Olsson, L.; Nielsen, J.
Gene deletion of cytosolic ATP: citrate lyase leads to altered organic acid production in Aspergillus niger
J. Ind. Microbiol. Biotechnol.
36
1275-1280
2009
Aspergillus niger
Manually annotated by BRENDA team
Ma, Z.; Chu, C.; Cheng, D.
A novel direct homogeneous assay for ATP citrate lyase
J. Lipid Res.
50
2131-2135
2009
Homo sapiens
Manually annotated by BRENDA team
Wellen, K.; Hatzivassiliou, G.; Sachdeva, U.; Bui, T.; Cross, J.; Thompson, C.
ATP-citrate lyase links cellular metabolism to histone acetylation
Science
324
1076-1080
2009
Homo sapiens
Manually annotated by BRENDA team
Sun, T.; Hayakawa, K.; Fraser, M.E.
ADP-Mg2+ bound to the ATP-grasp domain of ATP-citrate lyase
Acta Crystallogr. Sect. F
67
1168-1172
2011
Homo sapiens (P53396), Homo sapiens
Manually annotated by BRENDA team
Abdul Hamid, A.; Mokhtar, N.; Taha, E.; Omar, O.; Yusoff, W.
The role of ATP citrate lyase, malic enzyme and fatty acid synthase in the regulation of lipid accumulation in Cunninghamella sp. 2A1
Ann. Microbiol.
61
463-468
2011
Cunninghamella sp., Cunninghamella sp. 2A1
-
Manually annotated by BRENDA team
Chypre, M.; Zaidi, N.; Smans, K.
ATP-citrate lyase: a mini-review
Biochem. Biophys. Res. Commun.
422
1-4
2012
Homo sapiens, Mus musculus
Manually annotated by BRENDA team
Fan, F.; Williams, H.J.; Boyer, J.G.; Graham, T.L.; Zhao, H.; Lehr, R.; Qi, H.; Schwartz, B.; Raushel, F.M.; Meek, T.D.
On the catalytic mechanism of human ATP citrate lyase
Biochemistry
51
5198-5211
2012
Homo sapiens
Manually annotated by BRENDA team
Hynes, M.; Murray, S.
ATP-citrate lyase is required for production of cytosolic acetyl coenzyme A and development in Aspergillus nidulans
Eukaryot. Cell
9
1039-1048
2010
Aspergillus nidulans (Q5BAJ4 and Q5BAJ5), Aspergillus nidulans, Aspergillus nidulans 54 (Q5BAJ4 and Q5BAJ5)
Manually annotated by BRENDA team
Son, H.; Lee, J.; Park, A.R.; Lee, Y.W.
ATP citrate lyase is required for normal sexual and asexual development in Gibberella zeae
Fungal Genet. Biol.
48
408-417
2011
Fusarium graminearum, Fusarium graminearum GZ3639
Manually annotated by BRENDA team
Sun, T.; Hayakawa, K.; Bateman, K.S.; Fraser, M.E.
Identification of the citrate-binding site of human ATP-citrate lyase using X-ray crystallography
J. Biol. Chem.
285
27418-27428
2010
Homo sapiens (P53396), Homo sapiens
Manually annotated by BRENDA team
Zaidi, N.; Royaux, I.; Swinnen, J.V.; Smans, K.
ATP citrate lyase knockdown induces growth arrest and apoptosis through different cell- and environment-dependent mechanisms
Mol. Cancer Ther.
11
1925-1935
2012
Homo sapiens
Manually annotated by BRENDA team
Infantino, V.; Iacobazzi, V.; Palmieri, F.; Menga, A.
ATP-citrate lyase is essential for macrophage inflammatory response
Biochem. Biophys. Res. Commun.
440
105-111
2013
Homo sapiens
Manually annotated by BRENDA team
Tajima, A.; Murai, N.; Murakami, Y.; Iwamoto, T.; Migita, T.; Matsufuji, S.
Polyamine regulating protein antizyme binds to ATP citrate lyase to accelerate acetyl-CoA production in cancer cells
Biochem. Biophys. Res. Commun.
471
646-651
2016
Homo sapiens
Manually annotated by BRENDA team
Dulermo, T.; Lazar, Z.; Dulermo, R.; Rakicka, M.; Haddouche, R.; Nicaud, J.M.
Analysis of ATP-citrate lyase and malic enzyme mutants of Yarrowia lipolytica points out the importance of mannitol metabolism in fatty acid synthesis
Biochim. Biophys. Acta
1851
1107-1117
2015
Yarrowia lipolytica
Manually annotated by BRENDA team
Das, S.; Morvan, F.; Jourde, B.; Meier, V.; Kahle, P.; Brebbia, P.; Toussaint, G.; Glass, D.J.; Fornaro, M.
ATP citrate lyase improves mitochondrial function in skeletal muscle
Cell Metab.
21
868-876
2015
Mus musculus
Manually annotated by BRENDA team
Lee, J.H.; Jang, H.; Lee, S.M.; Lee, J.E.; Choi, J.; Kim, T.W.; Cho, E.J.; Youn, H.D.
ATP-citrate lyase regulates cellular senescence via an AMPK- and p53-dependent pathway
FEBS J.
282
361-371
2015
Homo sapiens
Manually annotated by BRENDA team
Chavez-Cabrera, C.; Marsch, R.; Bartolo-Aguilar, Y.; Flores-Bustamante, Z.R.; Hidalgo-Lara, M.E.; Martinez-Cardenas, A.; Cancino-Diaz, J.C.; Sanchez, S.; Flores-Cotera, L.B.
Molecular cloning and characterization of the ATP citrate lyase from carotenogenic yeast Phaffia rhodozyma
FEMS Yeast Res.
15
fov054
2015
Phaffia rhodozyma (A0A0K0NLA0), Phaffia rhodozyma, Phaffia rhodozyma NRRL Y-10922 (A0A0K0NLA0)
Manually annotated by BRENDA team
Chen, H.; He, X.; Geng, H.; Liu, H.
Physiological characterization of ATP-citrate lyase in Aspergillus niger
J. Ind. Microbiol. Biotechnol.
41
721-731
2014
Aspergillus niger, Aspergillus niger ATCC 1015
Manually annotated by BRENDA team
Rodriguez, S.; Denby, C.M.; Van Vu, T.; Baidoo, E.E.; Wang, G.; Keasling, J.D.
ATP citrate lyase mediates cytosolic acetyl-CoA biosynthesis increases mevalonate production in Saccharomyces cerevisiae
Microb. Cell Fact.
15
48
2016
Aspergillus nidulans, Yarrowia lipolytica, Lipomyces starkeyi, Mus musculus, Rhodotorula toruloides
Manually annotated by BRENDA team
Londono Gentile, T.; Lu, C.; Lodato, P.M.; Tse, S.; Olejniczak, S.H.; Witze, E.S.; Thompson, C.B.; Wellen, K.E.
DNMT1 is regulated by ATP-citrate lyase and maintains methylation patterns during adipocyte differentiation
Mol. Cell. Biol.
33
3864-3878
2013
Mus musculus
Manually annotated by BRENDA team
Xing, S.; van Deenen, N.; Magliano, P.; Frahm, L.; Forestier, E.; Nawrath, C.; Schaller, H.; Gronover, C.S.; Pruefer, D.; Poirier, Y.
ATP citrate lyase activity is post-translationally regulated by sink strength and impacts the wax, cutin and rubber biosynthetic pathways
Plant J.
79
270-284
2014
Arabidopsis thaliana
Manually annotated by BRENDA team
Hu, J.; Komakula, A.; Fraser, M.E.
Binding of hydroxycitrate to human ATP-citrate lyase
Acta Crystallogr. Sect. D
73
660-671
2017
Homo sapiens (P53396), Homo sapiens
Manually annotated by BRENDA team
Deb, D.K.; Chen, Y.; Sun, J.; Wang, Y.; Li, Y.C.
ATP-citrate lyase is essential for high glucose-induced histone hyperacetylation and fibrogenic gene upregulation in mesangial cells
Am. J. Physiol. Renal Physiol.
313
F423-F429
2017
Mus musculus (Q91V92)
Manually annotated by BRENDA team
Jernigan, F.E.; Hanai, J.I.; Sukhatme, V.P.; Sun, L.
Discovery of furan carboxylate derivatives as novel inhibitors of ATP-citrate lyase via virtual high-throughput screening
Bioorg. Med. Chem. Lett.
27
929-935
2017
Homo sapiens (P53396)
Manually annotated by BRENDA team
Hossain, A.; Van Gerven, R.; Overkamp, K.; Lbeck, P.; Tasplnar, H.; Trker, M.; Punt, P.
Metabolic engineering with ATP-citrate lyase and nitrogen source supplementation improves itaconic acid production in Aspergillus niger
Biotechnol. Biofuels
12
233
2019
Aspergillus niger
Manually annotated by BRENDA team
Rhee, J.; Solomon, L.A.; DeKoter, R.P.
A role for ATP citrate Lyase in cell cycle regulation during myeloid differentiation
Blood Cells Mol. Dis.
76
82-90
2019
Mus musculus (Q91V92)
Manually annotated by BRENDA team
Icard, P.; Wu, Z.; Fournel, L.; Coquerel, A.; Lincet, H.; Alifano, M.
ATP citrate lyase A central metabolic enzyme in cancer
Cancer Lett.
471
125-134
2020
Homo sapiens (P53396)
Manually annotated by BRENDA team
Lucenay, K.S.; Doostan, I.; Karakas, C.; Bui, T.; Ding, Z.; Mills, G.B.; Hunt, K.K.; Keyomarsi, K.
Cyclin E associates with the lipogenic enzyme ATP-citrate lyase to enable malignant growth of breast cancer cells
Cancer Res.
76
2406-2418
2016
Homo sapiens (P53396), Homo sapiens
Manually annotated by BRENDA team
Zhao, S.; Torres, A.; Henry, R.A.; Trefely, S.; Wallace, M.; Lee, J.V.; Carrer, A.; Sengupta, A.; Campbell, S.L.; Kuo, Y.M.; Frey, A.J.; Meurs, N.; Viola, J.M.; Blair, I.A.; Weljie, A.M.; Metallo, C.M.; Snyder, N.W.; Andrews, A.J.; Wellen, K.E.
ATP-citrate lyase controls a glucose-to-acetate metabolic switch
Cell Rep.
17
1037-1052
2016
Mus musculus (Q91V92)
Manually annotated by BRENDA team
Das, S.; Morvan, F.; Morozzi, G.; Jourde, B.; Minetti, G.C.; Kahle, P.; Rivet, H.; Brebbia, P.; Toussaint, G.; Glass, D.J.; Fornaro, M.
ATP citrate lyase regulates myofiber differentiation and increases regeneration by altering histone acetylation
Cell Rep.
21
3003-3011
2017
Homo sapiens (P53396), Mus musculus (Q91V92), Mus musculus
Manually annotated by BRENDA team
Koerner, S.K.; Hanai, J.I.; Bai, S.; Jernigan, F.E.; Oki, M.; Komaba, C.; Shuto, E.; Sukhatme, V.P.; Sun, L.
Design and synthesis of emodin derivatives as novel inhibitors of ATP-citrate lyase
Eur. J. Med. Chem.
126
920-928
2017
Homo sapiens (P53396)
Manually annotated by BRENDA team
Chen, Y.; Deb, D.K.; Fu, X.; Yi, B.; Liang, Y.; Du, J.; He, L.; Li, Y.C.
ATP-citrate lyase is an epigenetic regulator to promote obesity-related kidney injury
FASEB J.
33
9602-9615
2019
Homo sapiens (P53396), Homo sapiens, Mus musculus (Q91V92)
Manually annotated by BRENDA team
Chen, L.Y.; Lotz, M.; Terkeltaub, R.; Liu-Bryan, R.
Modulation of matrix metabolism by ATP-citrate lyase in articular chondrocytes
J. Biol. Chem.
293
12259-12270
2018
Homo sapiens (P53396), Homo sapiens
Manually annotated by BRENDA team
Bazilevsky, G.A.; Affronti, H.C.; Wei, X.; Campbell, S.L.; Wellen, K.E.; Marmorstein, R.
ATP-citrate lyase multimerization is required for coenzyme-A substrate binding and catalysis
J. Biol. Chem.
294
7259-7268
2019
Homo sapiens (P53396)
Manually annotated by BRENDA team
Khwairakpam, A.D.; Banik, K.; Girisa, S.; Shabnam, B.; Shakibaei, M.; Fan, L.; Arfuso, F.; Monisha, J.; Wang, H.; Mao, X.; Sethi, G.; Kunnumakkara, A.B.
The vital role of ATP citrate lyase in chronic diseases
J. Mol. Med.
98
71-95
2020
Homo sapiens (P53396)
Manually annotated by BRENDA team
Wei, X.; Schultz, K.; Bazilevsky, G.A.; Vogt, A.; Marmorstein, R.
Molecular basis for acetyl-CoA production by ATP-citrate lyase
Nat. Struct. Mol. Biol.
27
33-41
2020
Homo sapiens (P53396), Homo sapiens
Manually annotated by BRENDA team
Wei, J.; Leit, S.; Kuai, J.; Therrien, E.; Rafi, S.; Harwood, H.J.; DeLaBarre, B.; Tong, L.
An allosteric mechanism for potent inhibition of human ATP-citrate lyase
Nature
568
566-570
2019
Homo sapiens (P53396), Homo sapiens
Manually annotated by BRENDA team
Verschueren, K.H.G.; Blanchet, C.; Felix, J.; Dansercoer, A.; De Vos, D.; Bloch, Y.; Van Beeumen, J.; Svergun, D.; Gutsche, I.; Savvides, S.N.; Verstraete, K.
Structure of ATP citrate lyase and the origin of citrate synthase in the Krebs cycle
Nature
568
571-575
2019
Homo sapiens (P53396), Homo sapiens, Chlorobium limicola (Q9AQH6)
Manually annotated by BRENDA team
Bai, W.; Wang, P.; Hong, J.; Kong, W.; Xiao, Y.; Yu, X.; Zheng, H.; You, S.; Lu, J.; Lei, D.; Wang, C.; Wang, Q.; Liu, S.; Liu, X.; Tian, Y.; Chen, L.; Jiang, L.; Zhao, Z.; Wu, C.; Wan, J.
Earlier degraded Tapetum1 (EDT1) encodes an ATP-citrate lyase required for Tapetum programmed cell death
Plant Physiol.
181
1223-1238
2019
Oryza sativa Japonica Group (Q2QZ86)
Manually annotated by BRENDA team
Feng, X.; Zhang, L.; Xu, S.; Shen, A.Z.
ATP-citrate lyase (ACLY) in lipid metabolism and atherosclerosis An updated review
Prog. Lipid Res.
77
101006
2020
Homo sapiens (P53396), Homo sapiens
Manually annotated by BRENDA team
Li, H.; Sartorelli, V.
ATP citrate lyase a new player linking skeletal muscle metabolism and epigenetics
Trends Endocrinol. Metab.
29
202-204
2018
Homo sapiens (P53396)
Manually annotated by BRENDA team
Granchi, C.
Discovery of allosteric inhibition of human ATP-citrate lyase
Trends Pharmacol. Sci.
40
364-366
2019
Homo sapiens (P53396), Homo sapiens
Manually annotated by BRENDA team