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Reference on EC 2.3.3.14 - homocitrate synthase

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Ye, Z.H.; Bhattacharjee, J.K.
Lysine biosynthesis pathway and biochemical blocks of lysine auxotrophs of Schizosaccharomyces pombe
J. Bacteriol.
170
5968-5970
1988
Schizosaccharomyces pombe
Manually annotated by BRENDA team
Schmidt, H.; Bode, R.; Lindner, M.; Birnbaum, D.
Lysine biosynthesis in the yeast Candida maltosa: properties of some enzymes and regulation of the biosynthetic pathway
J. Basic Microbiol.
25
675-681
1985
Candida maltosa
-
Manually annotated by BRENDA team
Strassman, M.; Ceci, L.N.
Enzymatic formation of homocitric acid, an intermediate in lysine biosynthesis
Biochem. Biophys. Res. Commun.
14
262-267
1964
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Hogg, R.W.; Broquist, H.P.
Homocitrate formation in Neurospora crassa
J. Biol. Chem.
243
1839-1845
1968
Neurospora crassa
Manually annotated by BRENDA team
Demain, A.L.; Masurekar, P.S.
Lysine inhibition of in vivo homocitrate biosynthesis in Penicillium chrysogenum
J. Gen. Microbiol.
82
143-151
1974
Penicillium chrysogenum, Penicillium chrysogenum Wis. 54-1255
Manually annotated by BRENDA team
Tucci, A.F.; Ceci, L.N.
Homocitrate synthase from yeast
Arch. Biochem. Biophys.
153
742-750
1972
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Masurekar, P.S.; Demain, A.L.
Insensitivity of homocitrate synthase in extracts of Penicillium chrysogenum to feedback inhibition by lysine
Appl. Microbiol.
28
265-270
1974
Penicillium chrysogenum
Manually annotated by BRENDA team
Gaillardin, C.M.; Poirier, L.; Heslot, H.
A kinetic study of homocitrate synthetase activity in the yeast Saccharomyces lipolytica
Biochim. Biophys. Acta
422
390-406
1976
Saccharomycopsis lipolytica
Manually annotated by BRENDA team
Gray, G.S.; Bhattacharjee, J.K.
Biosynthesis of lysine in Saccharomyces cerevisiae: properties and spectrophotometric determination of homocitrate synthase activity
Can. J. Microbiol.
22
1664-1667
1976
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Gray, G.S.; Bhattacharjee, J.K.
Biosynthesis of lysine in Saccharomyces cerevisiae: Regulation of homocitrate synthase in analogue-resistant mutants
J. Gen. Microbiol.
97
117-120
1976
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Luengo, J.M.; Revilla, G.; Lopez, M.J.; Villanueva, J.R.; Martin, J.M.
Inhibition and repression of homocitrate synthase by lysine in Penicillium chrysogenum
J. Bacteriol.
144
869-876
1980
Penicillium chrysogenum
Manually annotated by BRENDA team
Takenouchi, E.; Tanaka, H.; Soda, K.
Homocitrate synthase of S-(beta-aminoethyl)-L-cysteine resistant mutant of Candida pelliculosa
J. Ferment. Technol.
59
429-433
1981
Wickerhamomyces anomalus
-
Manually annotated by BRENDA team
Shimizu, E.; Yamana, R.; Tanaka, H.; Soda, K.
Effects of a selenium analogue of L-lysine on growth of Candida pelliculosa
Agric. Biol. Chem.
48
2871-2872
1984
Wickerhamomyces anomalus
-
Manually annotated by BRENDA team
Banuelos, O.; Casqueiro, J.; Fierro, F.; Hijarrubia, M.J.; Gutierrez, S.; Matin, J.F.
Characterization and lysine control of expression of the lys1 gene of Penicillium chrysogenum encoding homocitrate synthase
Gene
226
51-59
1999
Penicillium chrysogenum
Manually annotated by BRENDA team
Jaklitsch, W.M.; Kubicek, C.P.
Homocitrate synthase from Penicillium chrysogenum
Biochem. J.
269
247-253
1990
Penicillium chrysogenum
Manually annotated by BRENDA team
Ramos, F.; Verhasselt, P.; Fellers, A.; Peeters, P.; Wach, A.; Dubois, E.; Volckaert, G.
Identification of the gene encoding a homocitrate synthase isoenzyme of Saccharomyces cerevisiae
Yeast
12
1315-1320
1996
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Perez-Campo, F.M.; Nicaud, J.M.; Gaillardin, C.; Dominguez, A.
Cloning and sequencing of the LYS1 gene encoding homocitrate synthase in the yeast Yarrowia lipolytica
Yeast
12
1459-1469
1996
Yarrowia lipolytica
Manually annotated by BRENDA team
Zheng, L.; White, H.R.; Dean, D.R.
Purification of the Acobacter vinelandii nifV-encoded homocitrate synthase
J. Bacteriol.
179
5963-5966
1997
Azotobacter vinelandii
Manually annotated by BRENDA team
Chen, S.; Brockenbrough, J.S.; Dove, J.E.; Aris, P.
Homocitrate synthase is located in the nucleus in the yeast Saccharomyces cerevisiae
J. Biol. Chem.
272
10839-10846
1997
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Feller, A.; Ramos, F.; Pierard, A.; Dubois, E.
In Saccharomyces cerevisiae, feedback inhibition of homocitrate synthase by lysine modulates the activation of LYS gene expression by Lys14p
Eur. J. Biochem.
261
163-170
1999
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Wulandari, A.P.; Miyazaki, J.; Kobashi, N.; Nishiyama, M.; Hoshino, T.; Yamane, H.
Characterization of bacterial homocitrate synthase involved in lysine biosynthesis
FEBS Lett.
522
35-40
2002
Thermus thermophilus
Manually annotated by BRENDA team
Banuelos, O.; Casqueiro, J.; Gutierrez, S.; Martin, J.F.
Overexpression of the lys1 gene in Penicillium chrysogenum: homocitrate synthase levels, alpha-aminoadipic acid pool and penicillin production
Appl. Microbiol. Biotechnol.
54
69-77
2000
Penicillium chrysogenum
Manually annotated by BRENDA team
Banuelos, O.; Casqueiro, J.; Steidl, S.; Gutierrez, S.; Brakhage, A.; Martin, J.F.
Subcellular localization of the homocitrate synthase in Penicillium chrysogenum
Mol. Gen. Genet.
266
711-719
2002
Saccharomyces cerevisiae, Penicillium chrysogenum
Manually annotated by BRENDA team
Andi, B.; West, A.H.; Cook, P.F.
Stabilization and characterization of histidine-tagged homocitrate synthase from Saccharomyces cerevisiae
Arch. Biochem. Biophys.
421
243-254
2004
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Andi, B.; West, A.H.; Cook, P.F.
Kinetic mechanism of histidine-tagged homocitrate synthase from Saccharomyces cerevisiae
Biochemistry
43
11790-11795
2004
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Andi, B.; West, A.H.; Cook, P.F.
Regulatory mechanism of Histidine-tagged homocitrate synthase from Saccharomyces cerevisiae: I. KINETIC STUDIES
J. Biol. Chem.
280
31624-31632
2005
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Andi, B.; Cook, P.F.
Regulatory mechanism of Histidine-tagged homocitrate synthase from Saccharomyces cerevisiae: II. THEORY
J. Biol. Chem.
280
31633-31640
2005
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Qian, J.; West, A.H.; Cook, P.F.
Acid-base chemical mechanism of homocitrate synthase from Saccharomyces cerevisiae
Biochemistry
45
12136-12143
2006
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Li, F.; Hagemeier, C.H.; Seedorf, H.; Gottschalk, G.; Thauer, R.K.
Re-citrate synthase from Clostridium kluyveri is phylogenetically related to homocitrate synthase and isopropylmalate synthase rather than to Si-citrate synthase
J. Bacteriol.
189
4299-4304
2007
Clostridium kluyveri
Manually annotated by BRENDA team
Kwon, E.S.; Jeong, J.H.; Roe, J.H.
Inactivation of homocitrate synthase causes lysine auxotrophy in copper/zinc-containing superoxide dismutase-deficient yeast Schizosaccharomyces pombe
J. Biol. Chem.
281
1345-1351
2006
Schizosaccharomyces pombe
Manually annotated by BRENDA team
Masukawa, H.; Inoue, K.; Sakurai, H.
Effects of disruption of homocitrate synthase genes on Nostoc sp. strain PCC 7120 photobiological hydrogen production and nitrogenase
Appl. Environ. Microbiol.
73
7562-7570
2007
Nostoc sp. PCC 7120 = FACHB-418 (P58637), Nostoc sp. PCC 7120 = FACHB-418
Manually annotated by BRENDA team
Qian, J.; Khandogin, J.; West, A.H.; Cook, P.F.
Evidence for a catalytic dyad in the active site of homocitrate synthase from Saccharomyces cerevisiae
Biochemistry
47
6851-6858
2008
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Quezada, H.; Aranda, C.; DeLuna, A.; Hernandez, H.; Calcagno, M.L.; Marin-Hernandez, A.; Gonzalez, A.
Specialization of the paralogue LYS21 determines lysine biosynthesis under respiratory metabolism in Saccharomyces cerevisiae
Microbiology
154
1656-1667
2008
Saccharomyces cerevisiae (P48570), Saccharomyces cerevisiae (Q12122), Saccharomyces cerevisiae
Manually annotated by BRENDA team
Bulfer, S.L.; Scott, E.M.; Couture, J.F.; Pillus, L.; Trievel, R.C.
Crystal structure and functional analysis of homocitrate synthase, an essential enzyme in lysine biosynthesis
J. Biol. Chem.
284
35769-35780
2009
Schizosaccharomyces pombe
Manually annotated by BRENDA team
Bulfer, S.L.; Scott, E.M.; Pillus, L.; Trievel, R.C.
Structural basis for L-lysine feedback inhibition of homocitrate synthase
J. Biol. Chem.
285
10446-10453
2010
Schizosaccharomyces pombe (Q9Y823), Schizosaccharomyces pombe
Manually annotated by BRENDA team
Okada, T.; Tomita, T.; Wulandari, A.P.; Kuzuyama, T.; Nishiyama, M.
Mechanism of substrate recognition and insight into feedback inhibition of homocitrate synthase from Thermus thermophilus
J. Biol. Chem.
285
4195-4205
2010
Thermus thermophilus
Manually annotated by BRENDA team
Hakoyama, T.; Niimi, K.; Watanabe, H.; Tabata, R.; Matsubara, J.; Sato, S.; Nakamura, Y.; Tabata, S.; Jichun, L.; Matsumoto, T.; Tatsumi, K.; Nomura, M.; Tajima, S.; Ishizaka, M.; Yano, K.; Imaizumi-Anraku, H.; Kawaguchi, M.; Kouchi, H.; Suganuma, N.
Host plant genome overcomes the lack of a bacterial gene for symbiotic nitrogen fixation
Nature
462
514-517
2009
Lotus japonicus (D0VY45), Lotus japonicus
Manually annotated by BRENDA team
Schoebel, F.; Jacobsen, I.D.; Brock, M.
Evaluation of lysine biosynthesis as an antifungal drug target: biochemical characterization of Aspergillus fumigatus homocitrate synthase and virulence studies
Eukaryot. Cell
9
878-893
2010
Aspergillus fumigatus (C7C437), Aspergillus fumigatus, Aspergillus fumigatus CBS 144.89 (C7C437)
Manually annotated by BRENDA team
Scott, E.M.; Pillus, L.
Homocitrate synthase connects amino acid metabolism to chromatin functions through Esa1 and DNA damage
Genes Dev.
24
1903-1913
2010
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Kumar, V.P.; West, A.H.; Cook, P.F.
Kinetic and chemical mechanisms of homocitrate synthase from Thermus thermophilus
J. Biol. Chem.
286
29428-29439
2011
Thermus thermophilus
Manually annotated by BRENDA team
Quezada, H.; Marin-Hernandez, A.; Aguilar, D.; Lopez, G.; Gallardo-Perez, J.C.; Jasso-Chavez, R.; Gonzalez, A.; Saavedra, E.; Moreno-Sanchez, R.
The Lys20 homocitrate synthase isoform exerts most of the flux control over the lysine synthesis pathway in Saccharomyces cerevisiae
Mol. Microbiol.
82
578-590
2011
Saccharomyces cerevisiae, Saccharomyces cerevisiae BY4741
Manually annotated by BRENDA team
Liu, F.; Wang, W.; Chen, B.Z.; Xie, B.G.
Homocitrate synthase expression and lysine content in fruiting body of different developmental stages in Flammulina velutipes
Curr. Microbiol.
70
821-828
2015
Flammulina velutipes (M1U949), Flammulina velutipes, Flammulina velutipes W23 (M1U949)
Manually annotated by BRENDA team
Gabriel, I.; Milewski, S.
Characterization of recombinant homocitrate synthase from Candida albicans
Protein Expr. Purif.
125
7-18
2016
Candida albicans
Manually annotated by BRENDA team
Wang, J.; Wu, Y.; Sun, X.; Yuan, Q.; Yan, Y.
De novo biosynthesis of glutarate via alpha-keto acid carbon chain extension and decarboxylation pathway in Escherichia coli
ACS Synth. Biol.
6
1922-1930
2017
Saccharomyces cerevisiae (P48570), Saccharomyces cerevisiae, Saccharomyces cerevisiae ATCC 204508 (P48570)
Manually annotated by BRENDA team
Suzuki, T.; Akiyama, N.; Yoshida, A.; Tomita, T.; Lassak, K.; Haurat, M.F.; Okada, T.; Takahashi, K.; Albers, S.V.; Kuzuyama, T.; Nishiyama, M.
Biochemical characterization of archaeal homocitrate synthase from Sulfolobus acidocaldarius
FEBS Lett.
594
126-134
2020
Sulfolobus acidocaldarius (Q4J989), Sulfolobus acidocaldarius DSM 639 (Q4J989)
Manually annotated by BRENDA team
Hashimoto, S.; Wongdee, J.; Songwattana, P.; Greetatorn, T.; Goto, K.; Tittabutr, P.; Boonkerd, N.; Teaumroong, N.; Uchiumi, T.
Homocitrate synthase genes of two wide-host-range Bradyrhizobium strains are differently required for symbiosis depending on host plants
Microbes Environ.
34
393-401
2019
Bradyrhizobium sp. SUTN9-2, Bradyrhizobium sp. DOA9 (A0A0S6UXF5), Bradyrhizobium sp. ORS 285 (A0A1Y6KBA1)
Manually annotated by BRENDA team
Nouwen, N.; Arrighi, J.F.; Cartieaux, F.; Chaintreuil, C.; Gully, D.; Klopp, C.; Giraud, E.
The role of rhizobial (NifV) and plant (FEN1) homocitrate synthases in Aeschynomene/photosynthetic Bradyrhizobium symbiosis
Sci. Rep.
7
448
2017
Bradyrhizobium sp. ORS 285 (A0A1Y6KBA1)
Manually annotated by BRENDA team